Academic literature on the topic 'Quinoxaline'

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Journal articles on the topic "Quinoxaline"

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El-Telbani, Emad M., Ibrahim Radini, and Sameh R. Elgogary. "Syntheses of tricyclic fused quinoxaline ring systems: Pyrazoloquinoxalines (a-review)." INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY 35, no. 02 (2025): 279. https://doi.org/10.59467/ijhc.2025.35.279.

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Quinoxaline derivatives have gained significant interest due to their diverse pharmacological activity and have been included in numerous marketed drugs used to treat of various diseases. Examples include glecaprevir (Mavyret), voxilaprevir (Vosevi), Balversa (L01EX16) (erdafitinib), carbadox, XK469R (NSC698215), and becampanel (AMP397). Among the five-membered fused tricyclic quinoxalines ring systems, the pyrazoloquinolines belong to the azaheterocyclic group as derivatives of quinoxalines and pyrazoles and have characterized by many biological and pharmaceutical properties. There are three
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Elgogary, Sameh R., Emad M. El-Telbani, and Ibrahim Radini. "Syntheses and Biological Activities of Tricyclic-fused Quinoxaline Ring Systems (A Review). Part I: Thienoquinoxalines." INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY 34, no. 02 (2024): 173. http://dx.doi.org/10.59467/ijhc.2024.34.173.

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Quinoxaline derivatives are an interesting class of heterocyclic compounds in drug discovery. It is rare in natural state, but their synthesis is easy to perform coupling between benzene and pyrazine rings. In addition, quinoxaline nucleus has received notable attention as an important pharmacophore that has broad-spectrum applications, especially in the fields of pharmaceutics and medicine. This review spotlights the biological activities and the different methods of preparation of three isomers of thienoquinoxalines, namely thieno[2,3-b]quinoxaline, thieno[3,4-b]quinoxaline, and thieno[2,3-g
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Soleymani, Mousa, and Mahdieh Chegeni. "The Chemistry and Applications of the Quinoxaline Compounds." Current Organic Chemistry 23, no. 17 (2019): 1789–827. http://dx.doi.org/10.2174/1385272823666190926094348.

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The quinoxaline derivatives are beneficial compounds because of their various medicinal and industrial applications. They are well-known for application in organic light emitting devices, polymers and pharmaceutical agents. The quinoxaline-containing polymers are applicable in optical devices due to their thermal stability and low band gap. There are many reported procedures for the synthesis of bis- and polyquinoxalines and quinoxaline-containing macrocycles. The quinoxaline-based compounds as fascinating structures are important subjects of interest in either basic or applied sciences. This
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El-Sawy, Eslam, Fatma Bassyouni, Sherifa Abu-Bakr, Hanaa Rady, and Mohamed Abdlla. "Synthesis and biological activity of some new 1-benzyl and 1-benzoyl-3-heterocyclic indole derivatives." Acta Pharmaceutica 60, no. 1 (2010): 55–71. http://dx.doi.org/10.2478/v10007-010-0004-0.

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Synthesis and biological activity of some new 1-benzyl and 1-benzoyl-3-heterocyclic indole derivativesStarting from 1-benzyl- (2a) and 1-benzoyl-3-bromoacetyl indoles (2b) new heterocyclic, 2-thioxoimidazolidine (4a, b), imidazolidine-2,4-dione (5a, b), pyrano(2,3-d)imida-zole (8a, band9a, b), 2-substituted quinoxaline (11a, b-17a, b) and triazolo(4,3-a)quinoxaline derivatives (18a, band19a, b) were synthesized and evaluated for their antimicrobial and anticancer activities. Antimicrobial activity screening performed with concentrations of 0.88, 0.44 and 0.22 μg mm-2showed that 3-(1-substitute
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Wu, Degui, Jian Zhang, Jianhai Cui, Wei Zhang, and Yunkui Liu. "AgNO2-mediated direct nitration of the quinoxaline tertiary benzylic C–H bond and direct conversion of 2-methyl quinoxalines into related nitriles." Chem. Commun. 50, no. 74 (2014): 10857–60. http://dx.doi.org/10.1039/c4cc01327a.

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A unique method for AgNO<sub>2</sub>-mediated direct nitration of the quinoxaline tertiary C–H bond and direct conversion of 2-methyl quinoxalines into 2-quinoxaline nitriles under oxidative conditions has been developed.
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Kasatkina, Svetlana O., Ekaterina E. Stepanova, Maksim V. Dmitriev, Ivan G. Mokrushin, and Andrey N. Maslivets. "Synthesis of pyrimido[1,6-a]quinoxalines via intermolecular trapping of thermally generated acyl(quinoxalin-2-yl)ketenes by Schiff bases." Beilstein Journal of Organic Chemistry 14 (July 11, 2018): 1734–42. http://dx.doi.org/10.3762/bjoc.14.147.

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Acyl(quinoxalin-2-yl)ketenes generated by thermal decarbonylation of 3-acylpyrrolo[1,2-a]quinoxaline-1,2,4(5H)-triones react regioselectively with Schiff bases under solvent-free conditions to form pyrimido[1,6-a]quinoxaline derivatives in good yields.
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Chaouiki, Abdelkarim, Maryam Chafiq, Mohamed Rbaa, et al. "New 8-Hydroxyquinoline-Bearing Quinoxaline Derivatives as Effective Corrosion Inhibitors for Mild Steel in HCl: Electrochemical and Computational Investigations." Coatings 10, no. 9 (2020): 811. http://dx.doi.org/10.3390/coatings10090811.

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There has been substantial research undertaken on the role of green synthesized corrosion inhibitors as a substantial approach to inhibit the corrosion of metals and their alloys in acidic environments. Herein, electrochemical studies, surface characterization, and theoretical modeling were adopted to investigate the corrosion inhibition proprieties of novel synthesized quinoxaline derivatives bearing 8-Hydroxyquinoline, namely 1-((8-hydroxyquinolin-5-yl) methyl)-3,6-dimethylquinoxalin-2(1H)-one (Q1) and 1-((8-hydroxyquinolin-5-yl)methyl) quinoxalin-2(1H)-one (Q2) on mild steel corrosion in 1
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Ridhima, Chauhan, S. Chundawat N., and Pal Singh Girdhar. "Quinoxaline Derivatives: Synthesis and Biological Significance." Pharmaceutical and Chemical Journal 10, no. 3 (2023): 137–47. https://doi.org/10.5281/zenodo.13995628.

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Quinoxaline is a well-known and important nitrogen-containing heterocyclic compound with a complex ring consisting of a benzene ring and a pyrazine ring. Different modified quinoxalines and their derivatives with various functional groups are an important part of biological science, and important research projects are introduced in this course. Many methods have been developed to combine them. The demonstration that many quinoxaline derivatives have many biological activities encourages research in this field. There are many useful drugs such as antibiotics, antibiotics, antibiotics, antibioti
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Ruiz, Diego M., Juan C. Autino, Nancy Quaranta, Patricia G. Vázquez, and Gustavo P. Romanelli. "An Efficient Protocol for the Synthesis of Quinoxaline Derivatives at Room Temperature Using Recyclable Alumina-Supported Heteropolyoxometalates." Scientific World Journal 2012 (2012): 1–8. http://dx.doi.org/10.1100/2012/174784.

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We report a suitable quinoxaline synthesis using molybdophosphovanadates supported on commercial alumina cylinders as catalysts. These catalysts were prepared by incipient wetness impregnation. The catalytic test was performed under different reaction conditions in order to know the performance of the synthesized catalysts. The method shows high yields of quinoxaline derivatives under heterogeneous conditions. Quinoxaline formation was obtained using benzyl,o-phenylenediamine, and toluene as reaction solvent at room temperature. The CuH2PMo11VO40supported on alumina showed higher activity in t
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Yadav, Deepika, Surendra Nath Pandeya, Sachin Kumar, and Shewta Sinha. "Biological Activity of Quinoxaline Derivatives." International Journal of Current Pharmaceutical Review and Research 2, no. 1 (2011): 34–46. https://doi.org/10.5281/zenodo.12699293.

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Quinoxaline derivatives constitute an important class of heterocycles in drug discovery. They areclinically effective as antibacterial, antifungal, anti-inflammatory, anticancer, anti-tubercular andantineoplastic agents. Interestingly, it also shows hypoglycemic and antiglaucoma activity.Modification in their structure has offered a high degree of diversity that has proven useful for thedevelopment of new therapeutic agents having improved potency and lesser toxicity. Consideringthe extensive research on quinoxaline in the past, it was essential to review the wide spectrum ofbiological activit
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Dissertations / Theses on the topic "Quinoxaline"

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Coez, Arnaud. "Synthèse de quinoxaline-2,3-dione." Paris 5, 1992. http://www.theses.fr/1992PA05P117.

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Guillon, Jean. "Contribution à l'étude de nouvelles pyrrolo [1,2-α] quinoxalines : potentiels antagonistes non-peptidiques du récepteur au glucagon". Caen, 1996. http://www.theses.fr/1996CAEN4058.

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Blache, Yves. "Hétérocyclisation en séries quinoxalinique et pyrido[2,3-b]pyrazinique : synthèse, structure, réactivité." Montpellier 1, 1991. http://www.theses.fr/1991MON13508.

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Horton, Aaron Michael. "Novel Reactive Dyes Based on Pyrimidine and Quinoxaline Systems." NCSU, 2009. http://www.lib.ncsu.edu/theses/available/etd-04302009-143537/.

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Fitzsimmons, Sara Ann. "Enzymology and structure-activity relationships of quinoxaline bioreductive cytotoxins." Thesis, University of Glasgow, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.295320.

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Ihara, Eiji. "Synthesis and Structure Analysis of Poly (2,3-quinoxaline)s." Kyoto University, 1992. http://hdl.handle.net/2433/74625.

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Desvignes, Nicole. "Etude physico-chimique et diélectrique de polymères thermostables pour condensateurs." Dijon, 1988. http://www.theses.fr/1988DIJOS017.

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Etude des propriétés physicochimiques et diélectriques de deux polymères thermostables solubles: les polyphénylquinoxalines et les polyhydantoïnes dans le but de les utiliser comme diélectriques pour condensateurs à haute capacité volumique et a haute stabilité thermique
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Ahmad, Abid Rafiq. "Studies of novel diazanaphthoquinones and ion-responsive fluorescent quinoxaline derivatives." Thesis, Brunel University, 1994. http://bura.brunel.ac.uk/handle/2438/7130.

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The work reported is divided into two parts: fIrstly a section dealing with the preparation of some novel diazanaphthoquinones and their reactions, especially the Diels-Alder reaction, and secondly an account of some quinoxaline derivatives and their fluorescence properties. Quinoxaline quinones containing electron-donating groups at both the 2- and 3- position have shown a difference in their stability and their behaviour in the Diels-Alder reaction compared to the stability and the reactions of quinoxaline quinone. Symmetrical dienes in the Diels-Alder reaction yielded the initial addition p
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Vieira, Mónica Andreia Almeida. "Monitoring antibiotics in the environment. Study of Quinoxaline derivatives bioactivity." Doctoral thesis, Faculdade de Ciências e Tecnologia, 2013. http://hdl.handle.net/10362/11350.

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Dissertação para obtenção do Grau de Doutor em Química Sustentável<br>Antimicrobial agents have revolutionized medicine and promoted an increase in average life expectancy of human populations worldwide. These drugs are used not only in human medicine but also in veterinary practice, in the treatment and prevention of infections, and in some regions in the world, as well as growth promoters, ensuring a greater and better animal production. The use of antimicrobial agents in animal production causes contamination of the final product with drug residues that are eventually distributed in human
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Poola, Bhaskar. "Synthesis and characterization of quinoxaline-functionalized, cage-annulated oxa- and thiacrown ethers and reaction chemistry of the diphosphine ligand 2,3-bis(diphenylphosphino)-N-p-tolylmaleimide (bmi) at triosmium carbonyl clusters." Thesis, University of North Texas, 2006. https://digital.library.unt.edu/ark:/67531/metadc5608/.

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Quinoxaline-functionalized, cage-annulated oxa- and thiacrown ethers have been synthesized as possible specific metal host systems. The synthesis and characterization of quinoxaline-functionalized, cage-annulated oxa- and thiacrown ethers have been described. The characterization of these host systems have been fully achieved in solution by using various techniques such as IR, 1H NMR, and 13C NMR spectroscopic methods, high-resolution mass spectrometry (HRMS), elemental microanalysis, and X-ray crystallographic analysis in case of one quinoxaline-functionalized, cage-annulated oxacrown ether c
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Books on the topic "Quinoxaline"

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Ashcroft, Martin John. Quinoxaline-2,3-dithiolate and its metal complexes. University of Manchester, 1994.

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Ahmad, Abid Rafiq. Studies of novel diazanaphthoquinones and ion-responsive fluorescent quinoxaline derivatives. Brunel University, 1994.

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Brown, D. J. Quinoxalines. John Wiley & Sons, Inc., 2004. http://dx.doi.org/10.1002/0471533408.

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Mamedov, Vakhid A. Quinoxalines. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-29773-6.

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Howells, Ian Robert. Synthetic studies on 1H-azepines benzimidazoles and quinoxalines. University of Salford, 1996.

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Synthesis and Design of Unsymmetrical Quinoxaline-Based Oligomer with Tunable Backbone. Logos Verlag Berlin, 2023.

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Quinoxalines. Wiley, 2004.

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Taylor, Edward C., Desmond J. Brown, and Jonathan A. Ellman. Quinoxalines Vol. 61. Wiley & Sons, Incorporated, John, 2004.

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Taylor, Edward C., Desmond J. Brown, and Jonathan A. Ellman. Quinoxalines, Spplement 2. Wiley & Sons, Incorporated, John, 2004.

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Taylor, Edward C., Desmond J. Brown, and Jonathan A. Ellman. Quinoxalines, Spplement 2. Wiley & Sons, Incorporated, John, 2008.

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Book chapters on the topic "Quinoxaline"

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Mamedov, Vakhid A. "Synthesis of Quinoxaline Macrocycles." In Quinoxalines. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-29773-6_5.

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Mamedov, Vakhid A. "Quinoxaline–As a Parent Heterocycle." In Quinoxalines. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-29773-6_1.

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Waring, Michael J. "Echinomycin and Related Quinoxaline Antibiotics." In Molecular Aspects of Anticancer Drug-DNA Interactions. Macmillan Education UK, 1993. http://dx.doi.org/10.1007/978-1-349-12356-8_7.

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Plé, Nelly, and Corinne Fruit. "Metalation of Pyrazine and Quinoxaline." In Topics in Heterocyclic Chemistry. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/7081_2012_95.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of ruthenium(III) complex with dihydroxy-quinoxaline." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54231-6_351.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of cobalt(II) benzoate adduct with quinoxaline." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54231-6_412.

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Mamedov, Vakhid A. "Synthesis of Quinoxalines." In Quinoxalines. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-29773-6_2.

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Mamedov, Vakhid A. "Synthesis of Pyrrolo[l,2-a]quinoxalines." In Quinoxalines. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-29773-6_3.

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Mamedov, Vakhid A. "Synthesis of Imidazo[1,5-a]- and Imidazo[1,2-a]quinoxalines." In Quinoxalines. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-29773-6_4.

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Mamedov, Vakhid A. "Rearrangements of Quinoxalin(on)es for the Synthesis of Benzimidazol(on)es." In Quinoxalines. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-29773-6_6.

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Conference papers on the topic "Quinoxaline"

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Ouedghiri-Idrissi, I. E., Z. Sofiani, A. Talbi, et al. "Photophysical study of 2,3-Diphenyl Quinoxaline thin films for potential applications in optoelectronic devices." In 2024 24th International Conference on Transparent Optical Networks (ICTON). IEEE, 2024. http://dx.doi.org/10.1109/icton62926.2024.10647382.

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Knorr, Erica S., Jordan C. Kelly, Daniel P. Harrison, and Thomas N. Rohrabaugh. "Effect of electron-donating and -withdrawing groups on the photophysical properties of iridium (iii) diphenyl quinoxaline complexes." In Organic Photonic Materials and Devices XXVII, edited by Ileana Rau, Okihiro Sugihara, and William M. Shensky. SPIE, 2025. https://doi.org/10.1117/12.3047905.

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"SEARCH FOR DRUG PROTOTYPES FOR NMDA- AND AMPA-RECEPTOR ANTAGONISTS AMONG QUINOXALINE AND PYRAZINOBENZIMIDAZOLE DERIVATIVES." In XI МЕЖДУНАРОДНАЯ КОНФЕРЕНЦИЯ МОЛОДЫХ УЧЕНЫХ: БИОИНФОРМАТИКОВ, БИОТЕХНОЛОГОВ, БИОФИЗИКОВ, ВИРУСОЛОГОВ, МОЛЕКУЛЯРНЫХ БИОЛОГОВ И СПЕЦИАЛИСТОВ ФУНДАМЕНТАЛЬНОЙ МЕДИЦИНЫ. IPC NSU, 2024. https://doi.org/10.25205/978-5-4437-1691-6-319.

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The project is dedicated to screening of ionotropic glutamate receptors inhibitors among pyrazinobenzimidazole and quinoxaline derivatives. The pyramidal neurons of the hippocampus of Wistar rat brain were used for the study. With the patch clamp technique, we found the most active compound — this is a representative of the quinoxaline class with the code name ZDM-15.
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Sushma, G. N., M. Suma, A. G. Pramod, and Y. F. Nadaf. "Structural, thermal, chemical and optoelectronic properties of the quinoxaline with DFT." In 3RD INTERNATIONAL CONFERENCE ON CONDENSED MATTER AND APPLIED PHYSICS (ICC-2019). AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0002148.

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Popović-Nikolić, Marija R., Katarina Nikolić, and Mara Aleksić. "DFT approach of the redox properties of brimonidine and varenicline." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.423pn.

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The redox properties of two quinoxaline derivatives, brimonidine and varenicline, previously studied electrochemically, were evaluated by performing a computational study. On the basis of some useful quantum chemical parameters the differences and similarities between their redox features were explained. The obtained results support the experimental findings that the redox processes of both compounds are under strong influence of the solution pH, whereas the reduction of brimonidine occurs easier than the reduction of varenicline, at corresponding pH values.
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Deva, Liliia, Iryna Yaremchuk, Tetiana Bulavinets, et al. "Yellow-green high-efficiency TADF OLED with phenoxazine and quinoxaline as emitter." In RAD Conference. RAD Centre, 2023. http://dx.doi.org/10.21175/rad.abstr.book.2023.14.3.

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Chatterjee, Rana, Sachinta Mahato, Anindita Mukherjee, Grigory V. Zyryanov, and Adinath Majee. "Synthesis of quinoxaline derivatives catalyzed by Brønsted acidic ionic liquid under solvent-free conditions." In PROCEEDINGS OF INTERNATIONAL CONFERENCE ON RECENT TRENDS IN MECHANICAL AND MATERIALS ENGINEERING: ICRTMME 2019. AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0018532.

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Pokladko-Kowar, Monika, Andrzej Danel, and Łukasz Chacaga. "Single-layer electroluminescent devices based on fluorene-1H-pyrazolo[3,4-b]quinoxaline co-polymers." In 8th Ibero American Optics Meeting/11th Latin American Meeting on Optics, Lasers, and Applications, edited by Manuel Filipe P. C. Martins Costa. SPIE, 2013. http://dx.doi.org/10.1117/12.2027574.

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Buravchenko, G., I. Treshchalin, S. Alexander, and A. Shchekotikhin. "PO-413 Estimation of antitumor activity of amino derivatives of quinoxaline-2-carbonitrile 1,4-dioxide." In Abstracts of the 25th Biennial Congress of the European Association for Cancer Research, Amsterdam, The Netherlands, 30 June – 3 July 2018. BMJ Publishing Group Ltd, 2018. http://dx.doi.org/10.1136/esmoopen-2018-eacr25.439.

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Ghattass, Khaled I., Sally El Sitt, Kazem Zibara, Makhlouf MJ Haddadin, Marwan El-Sabban, and Hala Ghali-Muhtasib. "Abstract A99: DCQ is a hypoxia-activated quinoxaline 1,4-dioxide that reduces breast cancer metastasis." In Abstracts: AACR Special Conference on Tumor Invasion and Metastasis - January 20-23, 2013; San Diego, CA. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.tim2013-a99.

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