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1

Pereira, Daniel Albuquerque. "Quorum sensing em cianobactérias." Universidade Federal de Minas Gerais, 2014. http://hdl.handle.net/1843/BUOS-9NFKZN.

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The terminology quorum sensing is used to identify a cellular communication phenomenon in the bacterial domain, which happens when a bacteria population reaches a defined cellular density. During the activation of the phenomenon changes in the expression of several genes and consequently in the physiology of the cell are triggered. Concerning cyanobacteria, there is a lack of information about quorum sensing. Some studies show that quorum sensing inducer compounds may alter physiological characteristics of certain cyanobacteria strains. Besides that, indirect evidences have shown that cellular
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2

Teplitski, Max I. "Quorum sensing in Sinorhizobium meliloti and effect of plant signals on bacterial quorum sensing." The Ohio State University, 2002. http://rave.ohiolink.edu/etdc/view?acc_num=osu1029777185.

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Teplitski, Maxim Igorevich. "Quorum sensing in Sinorhizobium meliloti and effect of plant signals on bacterial quorum sensing /." The Ohio State University, 2002. http://rave.ohiolink.edu/etdc/view?acc_num=osu1486463803600062.

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Teplitski, Maxim I. "Quorum sensing in Sinorhizobium meliloti and effect of plant signals on bacterial quorum sensing." Columbus, Ohio : Ohio State University, 2002. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1029777185.

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Thesis (Ph. D.)--Ohio State University, 2002.<br>Title from first page of PDF file. Document formatted into pages; contains xi, 148 p.; also includes graphics (some col.). Includes abstract and vita. Advisor: Wolfgang D. Bauer, Dept. of Horticulture and Crop Science. Includes bibliographical references (p. 127-148).
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5

Weber, Marc. "Stochastic Effects in Quorum Sensing." Doctoral thesis, Universitat de Barcelona, 2014. http://hdl.handle.net/10803/276154.

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Stochastic fluctuations, or noise, are ubiquitous in biological systems and play an important role in many cellular processes. Experimental evidences have shown that noise affects the reliability of cell coordination in populations of communicating cells. In this thesis, we study the effects of stochasticity in the emergence of collective behavior in populations of bacteria communicating by QS. We focus on the genetic switch as a paradigm of cellular decision making in both natural and synthetic bacterial systems. Our approach is based on mathematical modeling and stochastic simulations, both
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Lewenza, William Shawn. "Quorum sensing in Burkholderia cepacia." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0017/NQ54796.pdf.

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7

Isherwood, Karen Elizabeth. "Quorum sensing in Yersinia pestis." Thesis, University of Nottingham, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.364667.

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Atkinson, Steven. "Quorum sensing in Yersinia pseudotuberculosis." Thesis, University of Nottingham, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.287185.

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Hardman, Andrea M. "Quorum sensing in vibrio anguillarum." Thesis, University of Nottingham, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.363936.

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10

Buckley, Catherine M. F. "Quorum sensing in Yersinia pseudotuberculosis." Thesis, University of Nottingham, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.273108.

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11

Chalker, Victoria J. "Quorum sensing in Vibrio anguillarum." Thesis, University of Nottingham, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.325714.

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12

Sung, Julia Mei Li. "Quorum sensing in Staphylococcus intermedius." Thesis, Royal Veterinary College (University of London), 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.420706.

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13

Christie, Joseph Martin. "The search for quorum sensing inhibitors." Thesis, University of Ulster, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.529557.

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14

Nieto, Penalver Carlos Gabriel. "Quorum sensing chez Methylobacterium extorquens AM1." Toulouse 3, 2006. http://www.theses.fr/2006TOU30082.

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Le quorum sensing est un mécanisme de régulation physiologique des bactéries en réponse à des fluctuations de densité de population. Ce projet vise à déterminer si le quorum sensing existe chez la bactérie méthylotrophe facultative et à caractériser ce système. Il est établi que M. Extorquens AM1 possède un système de quorum sensing hiérarchisé. L'enzyme MlaI catalyse la synthèse des molécules signal C14:1-HSL et C14:2-HSL. MsaI, une seconde enzyme, catalyse la synthèse des C8-HSL et C6-HSL. MsaI est impliquée dans le contrôle positif de l'expression de mlaI et la production concomitante des C
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15

Montagut, Cañete Enrique José. "Immunochemical diagnostic strategies based on Quorum Sensing." Doctoral thesis, Universitat de Barcelona, 2021. http://hdl.handle.net/10803/670762.

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The final goal of the thesis was to improve the diagnostic of infections caused by P. aeruginosa and S. aureus through a better understanding of the bacterial communication process known as Quorum Sensing (QS) and its implication on the pathogenesis. Subsequently, this objective was based on the development of immunochemical methods to profile the expression of different QS signalling molecules, as tools to investigate the mechanisms involved in the pathogenesis of S. aureus and P. aeruginosa and also to assess the potential role of these molecules as biomarkers of infection. In this thesis
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16

Hasegawa, Hiroaki. "Quorum sensing in soft-rotting Erwinia carotovora." Diss., Columbia, Mo. : University of Missouri-Columbia, 2005. http://hdl.handle.net/10355/5815.

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Thesis (Ph. D.)--University of Missouri-Columbia, 2005.<br>The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Title from title screen of research.pdf file viewed on (May 22, 2006) Vita. Includes bibliographical references.
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Kotte, Ann-Katherine. "RNPP-type quorum sensing in Clostridium acetobutylicum." Thesis, University of Nottingham, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.606841.

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Clostridium acetobutylicum is a Gram-type positive, strictly fennentative, endospore-forming bacterium. It gains energy by converting sugars into organic acids during the first part of its life cycle and into solvents during the second part. This work investigated whether RNPP-type quorum sensing is involved in the regulation of key features such as solventogenesis and sporulation. It identified eight putative RNPP-type Quorum ,S,ensing ,S,ystems (qssA to qssH) in the genome of C. acetobutylicul11, each consisting of a putative Quorum ,S,ensing Regulator (qsr) and Quorum ,S,ensing E.eptide (qs
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Harty, Christopher. "Bacterial quorum sensing molecules as immune modulators." Thesis, University of Nottingham, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.422737.

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Lynch, Martin J. "Quorum sensing in Aeromonas hydrophila biofilm formation." Thesis, University of Nottingham, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.324695.

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Wilson, Michael P. "Protein secretion and quorum sensing in Salmonella." Thesis, University of Newcastle Upon Tyne, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.275515.

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Muharram, Siti Hanna. "Antagonism of quorum sensing in Staphylococcus aureus." Thesis, University of Nottingham, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.438365.

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Paiva, Franciely Paula Toniolo de. "Quorum sensing em Escherichia coli enteropatogênica atípica." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/87/87131/tde-23032011-172812/.

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Escherichia coli enteropatogênica atípica (aEPEC) faz parte de um grupo de patógenos capazes de formar um tipo de lesão característica em cultura de tecidos epiteliais, denominada attaching and effacing (A/E). Os genes que são necessários para produção da lesão A/E estão localizados em uma ilha de patogenicidade denominada região LEE (locus of enterocyte effacement). A transcrição de genes da região LEE está sujeita a regulação por vários fatores, entre eles quorum sensing, termo utilizado para designar um mecanismo de regulação gênica dependente da concentração celular. Esse mecanismo é usado
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23

Mamani, Flores Sigde Karina. "Régulation par le quorum sensing chez la bactérie biolixiviante Acidithiobacillus ferrooxidans." Thesis, Aix-Marseille, 2016. http://www.theses.fr/2016AIXM4117.

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Le Quorum sensing (QS) est un système de communication bactérienne capable de réguler divers processus cellulaires qui dépendent de la densité de la population microbienne. Chez les bactéries à Gram négatif, cela se produit par production de molécules de signalisation auto-inductrices (AI), les acyl homosérine lactones (AHL). La libération d´AHL à l'extérieur de la cellule est détectée par la population bactérienne provoquant en réponse la régulation de l'expression de certains gènes (régulon QS).Notre laboratoire a étudié et identifié un système QS fonctionnel dans la souche Acidithiobacillus
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De, Vizio Daniela. "Investigation of quorum sensing process in Bacillus licheniformis." Thesis, University of Westminster, 2011. https://westminsterresearch.westminster.ac.uk/item/8zxw2/investigation-of-quorum-sensing-process-in-bacillus-licheniformis.

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Quorum sensing is a well-established system of communication adopted by a number of bacterial, and some fungal, populations. This cell density dependent phenomenon is based on the accumulation of small diffusible molecules, termed as quorum sensing molecules, in the extracellular milieu until a threshold concentration triggers alteration in the expression of specific genes culminating in variety of responses including virulence, bioluminescence, sporulation, biofilm formation and secondary metabolites production. In Bacilli, quorum sensing is mediated by small peptides that control competence,
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25

Yuan, Lihui. "Quorum sensing regulated gene expression in Porphyromonas gingivalis." [Gainesville, Fla.] : University of Florida, 2005. http://purl.fcla.edu/fcla/etd/UFE0010043.

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Thesis (Ph.D.)--University of Florida, 2005.<br>Typescript. Title from title page of source document. Document formatted into pages; contains 134 pages. Includes Vita. Includes bibliographical references.
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26

Li, Jun. "Systematic investigation of quorum sensing in Escherichia coli." College Park, Md. : University of Maryland, 2007. http://hdl.handle.net/1903/6742.

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Thesis (Ph. D.) -- University of Maryland, College Park, 2007.<br>Thesis research directed by: Chemical Engineering. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.
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27

Popat, Roman. "Communication, cooperation & conflict in quorum sensing bacteria." Thesis, University of Nottingham, 2012. http://eprints.nottingham.ac.uk/12468/.

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The scientific community has gathered an extremely detailed and sophisticated understanding of the genetic and molecular underpinnings of microbial communication. How these microbial communication systems arise and are maintained over evolutionary time-scales however has received relatively little attention. Some major questions remain unanswered such as; what is the function of small diffusible molecules? How does population structure affect the dynamics of social communication and what is the link between the ecology of communication and the virulence of a pathogenic population? Borrowing co
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Jahan, Nasrin. "Structural studies of Vibrio cholerae quorum sensing proteins." Thesis, University of St Andrews, 2011. http://hdl.handle.net/10023/2565.

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The spread of cholera is always associated with contaminated food or water and this is the reason this disease has been endemic in developing countries for centuries due to their lack of proper sanitation facilities and poor or no infrastructure for sewage systems. Cholera can spread quickly and sporadically after any natural disaster that destroys the sewage system or safe drinking water supply of both developed and undeveloped countries. In Southeast Asia in December 2004 and in Pakistan and Haiti 2010, cholera outbreaks followed the natural disasters; with most of the cholera victims being
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Stavroulakis, Georgios. "Attenuation of quorum sensing using computationally designed polymers." Thesis, Cranfield University, 2010. http://dspace.lib.cranfield.ac.uk/handle/1826/4578.

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It is generally accepted that the majority of Gram-negative and Gram-positive bacteria communicate via production and sensing of small signal molecules, autoinducers. The ability of bacteria to sense their population density is termed quorum sensing (QS). Quorum sensing controls certain phenotypic traits, particularly virulence factors and biofilm formation. In this project a new solution for the attenuation of quorum sensing which involves selective sequestering of the signal molecules using rationally designed synthetic polymers was explored.
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Kirke, David F. "Protein-nucleic acid interactions regulating bacterial quorum sensing." Thesis, University of Nottingham, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.364668.

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Viegas, Ana. "Quorum sensing na prática clínica: mito ou realidade." Master's thesis, [s.n.], 2013. http://hdl.handle.net/10284/4087.

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Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Ciências Farmacêuticas<br>Este trabalho tem como objetivo analisar, através desta revisão bibliográfica, a possibilidade de se estudar mais detalhadamente o fenómeno de QS e avaliar a hipótese de se utilizar este mecanismo a favor do tratamento de algumas patologias. A influência dos microrganismos na saúde e/ou enfermidade da população, é uma questão incontornável. É de facto relevante que se efetuem estudos acerca do modo como estes seres sobrevivem, c
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Koziski, Jessica Marie. "Genetic Analysis of the Quorum Sensing Regulator EsaR." Thesis, Virginia Tech, 2008. http://hdl.handle.net/10919/34229.

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Pantoea stewartii subsp. stewartii is the causative agent of Stewartâ s wilt disease in maize plants. The bacteria are injected into the plant by corn flea beetles during feeding. They colonize the xylem and overproduce a capsular exopolysaccharide (EPS) at high cell densities. The production of EPS is regulated by an EsaI/EsaR quorum sensing mechanism, homologous to the LuxI/R system. Although activation of the EPS encoding genes by EsaR occurs after it complexes to the AHL (3-oxo-C6-HSL), unlike the LuxI/R system, this activation occurs by a different mechanism. At low cell densities, dimer
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Jones, Faye-Ellen. "Inhibition of N-acyl-homoserine lactone quorum sensing." Thesis, University of Aberdeen, 2000. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU602017.

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Quorum-sensing amongst Gram-negative bacteria is an important method of intercellular communication required for conveying information about population density. The extracellular accumulation of the signal molecule involved, N-acyl homoserine lactone (AHL), leading to increases in internal physiological concentration, allows phenotypic switching to occur that is beneficial to the bacterial population. In our laboratory, analysis of the effect of AHL on phenotype currently involves creating null mutants unable to produce AHL, then reintroducing the signal molecule exogenously. With the increasi
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Sharif, Dilara Islam. "Quorum sensing in the cyanobacterium Gloeothece PCC 6909." Thesis, Swansea University, 2008. https://cronfa.swan.ac.uk/Record/cronfa42295.

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The thesis sought to study whether cyanobacteria utilise the process of quorum sensing during their growth, to identify any quorum sensing molecules produced by the cyanobacteria Gloeothece PCC 6909/1 and to study the effect of any such molecules in aexenic cultures of the organism. The study presents the first evidence of N-octanoyl homoserine lactone (C8-HSL) quorum sensing molecule from axenic cultures of the cyanobacterium PCC 6909 and its sheathless mutant PCC 6909/1 and that the production of this molecule followed a density dependent accumulation, a common feature of many quorum sensing
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Portela, Gislaine Simões. "Bioprospecção de plantas medicinais Com atividade antimicrobiana e anti-quorum sensing." Universidade Federal da Paraí­ba, 2011. http://tede.biblioteca.ufpb.br:8080/handle/tede/6650.

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Made available in DSpace on 2015-05-14T12:56:01Z (GMT). No. of bitstreams: 1 arquivototal.pdf: 944601 bytes, checksum: c211a613a7ca088bee34c901c685111c (MD5) Previous issue date: 2011-12-16<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES<br>The objective of this research was to investigate the existence of antimicrobial plant compounds and anti-quorum sensing in oral biofilms. The plants used in this study were: Schinus terebinthifolius Raddi (aroeira da praia); Lippia sidoides Scham (alecrim pimenta); Abarema cochiliacarpos (Gomes) B. & J.W. Grimes (barbatimão); Ana
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Pietschke, Cleo I. [Verfasser]. "Inter-kingdom communication : quorum sensing and quorum quenching in the metaorganism Hydra / Cleo I. Pietschke." Kiel : Universitätsbibliothek Kiel, 2018. http://d-nb.info/1173163190/34.

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Bergonzi, Céline. "Étude, caractérisation et ingénierie de lactonases pour l'inhibition de la virulence et des biofilms bactériens." Thesis, Aix-Marseille, 2018. http://www.theses.fr/2018AIXM0241.

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Certains microorganismes sont capables de communiquer en utilisant des molécules et d’utiliser ce système pour réguler des comportements en fonction de la densité cellulaire. Ce système de communication, appelé quorum sensing (QS), régule des comportements bactériens, tels que la virulence et la formation de biofilm. Les molécules signal les plus étudiées sont les acyle-homosérine lactones (AHLs). Les enzymes qui sont capables de dégrader ces molécules peuvent couper la communication bactérienne, et se comportent ainsi comme des inhibiteurs de virulence et de biofilm. Ce phénomène, appelé quor
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Rémy, Benjamin. "Développement d'une nouvelle génération de pansements antimicrobiens à base d'enzyme à activité lactonase." Thesis, Aix-Marseille, 2018. http://www.theses.fr/2018AIXM0391.

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Des bactéries utilisent un système de communication, quorum sensing (QS), qui leur permet de synchroniser leur comportement proportionnellement à la densité de population. Des bactéries pathogènes utilisent le QS pour coordonner leur virulence et la formation de biofilm. Bloquer le QS, quorum quenching (QQ), constitue donc une piste pour étendre l'arsenal thérapeutique antibactérien. Durant cette thèse, SsoPox, une lactonase hyperstable hydrolysant les acyl homosérine lactones (AHL) impliquées dans le QS de bactéries à Gram négative pathogènes comme P. aeruginosa, a été étudiée. Son utilisatio
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Doberva, Margot. "Le quorum sensing bactérien dans l'environnement marin : diversité moléculaire et génétique des auto-inducteurs." Thesis, Paris 6, 2016. http://www.theses.fr/2016PA066049/document.

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L'environnement marin est constitué d'écosystèmes nombreux et variés, qui sont habités par des organismes appartenant aux trois domaines du vivant dont celui des bactéries. La coopération bactérienne est basée sur un mécanisme moléculaire appelé quorum sensing (QS). Ce système est dépendant de la densité cellulaire de la communauté, ce qui permet aux bactéries de synchroniser leur expression génétique, pour coordonner certaines de leurs activités physiologiques. Les bactéries produisent plusieurs types de molécules signal dont les acyl-homosérines lactones (AHLs ou AI-1) et le furanosyl dieste
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Huedo, Moreno Pol. "Fatty acid-mediated quorum sensing systems in stenotrophomonas maltophilia." Doctoral thesis, Universitat Autònoma de Barcelona, 2014. http://hdl.handle.net/10803/285570.

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Els sistemes de comunicació bacteriana -coneguts com quorum sensing (QS)- a través de molècules senyalitzadores del tipus àcid gras han despertat molt d’interès en els darrers anys ja que s’ha vist que molts bacteris patògens els utilitzen per regular funcions relacionades amb la virulència. Es coneix que Stenotrophomonas maltophilia presenta el sistema de QS DSF (Diffusible Signal Factor) el qual és controlat pels gens que conformen el clúster rpf (Regulation of Pathogenecity Factors). No obstant, no està clar els mecanismes pels quals S. maltophilia sintetitza i sensa les molècules senyal ai
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Schmidt, Silvia. "Biological control activity and quorum sensing in Burkholderia sp /." [S.l.] : [s.n.], 2009. http://opac.nebis.ch/cgi-bin/showAbstract.pl?sys=000278486.

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Lupp, Claudia. "Quorum sensing in the Vibrio fischeri-Euprymna scolopes symbiosis." Thesis, University of Hawaii at Manoa, 2003. http://hdl.handle.net/10125/1260.

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Quorum sensing is a cell density-dependent bacterial gene regulatory mechanism used for the expression of colonization-related genes. The symbiotic relationship between the luminescent bacterium Vibrio fischeri and the Hawaiian bobtail squid Euprymna scolopes serves as a model system to study the molecular processes underlying bacterial colonization. This system is especially well-suited for the investigation of the impact of quorum sensing on colonization because (i) it is an easily accessible, natural, two-species colonization model, and (ii) quorum sensing regulates luminescence expression
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Fagerlind, Magnus Biotechnology &amp Biomolecular Sciences Faculty of Science UNSW. "Mathematical modelling of bacterial quorum sensing and biofilm formation." Awarded by:University of New South Wales. Biotechnology & Biomolecular Sciences, 2008. http://handle.unsw.edu.au/1959.4/43095.

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To date, bacterial resistance to antibiotics is an increasing problem and there is a growing appreciation that biofilm formation is a significant contributor to antibiotic resistance. This has led to .increased research on ways to reduce/control biofilm formation. One such target is bacterial cell-cell communication that allows bacteria to coordinate gene expression, and that has been shown to be involved in biofilm formation and production of virulence factors. By interfering with this communication system it should be possible to control gene expression and thus inhibit production of virulen
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Peng, Hanjing. "Development of Bacterial Quorum Sensing Inhibitors and Molecular Probes." Digital Archive @ GSU, 2012. http://digitalarchive.gsu.edu/chemistry_diss/73.

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Bacterial quorum sensing is regarded as a novel target for the design of antimicrobials. Based on lead structures identified from HTS, 39 analogues have been synthesized and evaluated in Vibrio haveyi. Potent inhibitors with IC50 values at single-digit micromolar concentrations for AI-2 mediated quorum sensing have been identified. On the second project, post-synthesis modifications of DNA provide easy functionalizations for expanded applications such as aptamer selection. A CBT-modified thymidine analogue (CBT-TTP) has been synthesized and used for enzymatic incorporation into DNA. Post-synth
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Lam, Howard Andrew. "Cranberry derived materials modulate quorum sensing in Pseudomonas aeruginosa." Thesis, McGill University, 2013. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=114290.

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Cranberry-derived materials (CDMs) have recently been shown to block the group associated swarming motility in Pseudomonas aeruginosa without blocking swimming or twitching motilities. However, their mechanism of action is as of yet unknown. We hypothesized that these CDMs interfere with communication pathways important in swarming called quorum sensing (QS) and measured the impact of the CDMs on QS at three levels: QS signalling gene transcription, QS signal production, and activity/production of QS-controlled virulence factors. Crude cranberry powder extract (CP) repressed the las and rhl sy
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Ruparell, Avika. "Interplay between quorum sensing and metabolism in Pseudomonas aeruginosa." Thesis, University of Nottingham, 2012. http://eprints.nottingham.ac.uk/12690/.

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The important human pathogen Pseudomonas aeruginosa causes a broad-spectrum of diseases including life threatening infections. A cell density-dependent regulatory network termed quorum sensing (QS) is pivotal in the control of P. aeruginosa pathogenicity, and the signal molecules employed are N-acyl-L-homoserine lactones (AHLs) and the Pseudomonas quinolone signal (PQS). Production of these QS signal molecules (QSSMs) requires precursors including fatty acids, S-adenosyl-L-methionine (SAM) and aromatic amino acids. SAM is derived from the activated methyl cycle (AMC) which is an important path
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Williams, Headley St Edward. "Investigation of a Quorum sensing molecule in Aspergillus Nidulans." Thesis, University of Westminster, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.507844.

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Hale, Lisa Ann. "The Role of Quorum Sensing in Rhodobacter sphaeroides WS8N." Thesis, Oxford Brookes University, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.515275.

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Middleton, Barry John. "Quorum sensing cross-talk in cystic fibrosis lung pathogens." Thesis, University of Nottingham, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.288998.

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Enfield, Catherine L. "Quorum sensing, DNA replication and virulence in Escherichia coli." Thesis, University of Nottingham, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.435397.

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