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1

Dr., Preeti Patanjali. "A Culture that Communicates: An Ethnographic Study of Haryana's Traditional Food 'Raabdi'." Literary Druid 5, no. 3 (2023): 10–14. https://doi.org/10.5281/zenodo.8243108.

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<em>India is a vault of diverse cultures, languages, rituals and traditions. Every state has its own ethnic individuality evident in its material and non-material culture, viz. food, clothes, jewellery, customs, etc. Primitively, food is a basic biological necessity for sustenance, but, symbolically, it is enmeshed with varied connotations that are, more or less, indicative of a specific ethnicity. Thus, the present research study would closely look at &lsquo;raabdi&rsquo;, the traditional food of Haryana, to bring forth the semiotic and symbolic implications in terms of social, regional and c
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2

Isengard, Laura. "Katastrophe und Rettung bei Stifter und Raabe." Literatur für Leser 44, no. 3 (2021): 235–50. http://dx.doi.org/10.3726/lfl.2021.03.03.

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Abstract Die folgenden Überlegungen befragen die beiden Branderzählungen Kazensilber von Adalbert Stifter und Frau Salome von Wilhelm Raabe auf spezifisch Poetiken der Katastrophe. Stifters Kazensilber fängt zwei katastrophale Ereignisse in Rettung auf. Dies gelingt über die Figur des braunen Mädchens, das innerhalb der realistischen Erzählung ebenso rätselhaft wie stumm bleibt. Die an keine transzendentale Instanz mehr gebundene Rettung markiert eine Leerstelle im Text, die zunächst durch die Zunahme des Erzähltempos kaschiert wird, schlussendlich jedoch aus der (Text-)Ordnung exkludiert werd
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3

Haas, Rosemarie. "Raabe, der Rabe, „The Raven“. Beobachtungen zur Intertextualität in Raabes Erzählung „Das Odfeld“." Jahrbuch der Raabe-Gesellschaft 33, no. 1 (1992): 139–64. http://dx.doi.org/10.1515/9783110243819.139.

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4

McCormick, Ian, Robert Butcher, Jacqueline Ramke, et al. "The Rapid Assessment of Avoidable Blindness survey: Review of the methodology and protocol for the seventh version (RAAB7)." Wellcome Open Research 9 (March 8, 2024): 133. http://dx.doi.org/10.12688/wellcomeopenres.20907.1.

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The Rapid Assessment of Avoidable Blindness (RAAB) is a population-based cross-sectional survey methodology used to collect data on the prevalence of vision impairment and its causes and eye care service indicators among the population 50 years and older. RAAB has been used for over 20 years with modifications to the protocol over time reflected in changing version numbers; this paper describes the latest version of the methodology–RAAB7. RAAB7 is a collaborative project between the International Centre for Eye Health and Peek Vision with guidance from a steering group of global eye health sta
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Scheuermann, Barbara. "Immermanns „Münchhausen“ als Subtext von Raabes „Stopfkuchen“? Zu einem Konstrukt und seinem Weiterleben in der Raabe-Philologie." Jahrbuch der Raabe-Gesellschaft 53, no. 1 (2012): 27–50. http://dx.doi.org/10.1515/raabe-2012-0004.

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6

Tufa, Milkessa Edae, and Hessan Nagesso Gafarso. "The Magic Beyond Ritual”- Exploring Raaba Ritual and Ritualization Among Arsi Oromos of Ethiopia." International Journal of Multicultural and Multireligious Understanding 5, no. 2 (2018): 24. http://dx.doi.org/10.18415/ijmmu.v5i2.227.

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The purpose of this (mega) research project is to investigate the Raabaa Ritual and ritualization, one of the indigenous beliefs and Gada system practices in Oromo culture, among the Arsi Oromo. The Raabaa ritual is indigenous ritual practices which exercised by Arsi Oromo according to their Baalli. To this end, the researchers observed the ritual sites where the Raabaa ritual takes place. Besides, an interview with 13 key informants and 5 FGDs were conducted to collect wider data on the subject matter. Methodological the researchers’ were employee qualitative approach. The study found out tha
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7

Oh, Shintaek. "Inspecting Peter B. Raabe’s Philosophical Counseling." Journal of Humanities and Social sciences 21 12, no. 6 (2021): 3013–22. http://dx.doi.org/10.22143/hss21.12.6.212.

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8

Kloner, Robert A., Coleman Gross, Jinwei Yuan, Ansgar Conrad, and Pablo E. Pergola. "Effect of Patiromer in Hyperkalemic Patients Taking and Not Taking RAAS Inhibitors." Journal of Cardiovascular Pharmacology and Therapeutics 23, no. 6 (2018): 524–31. http://dx.doi.org/10.1177/1074248418788334.

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Introduction: Hyperkalemia (potassium &gt;5.0 mEq/L) affects heart failure patients with renal disease regardless of the use of renin–angiotensin–aldosterone system inhibitors (RAASi). The open-label TOURMALINE study showed that patiromer, a sodium-free, nonabsorbed potassium binder, lowers serum potassium of hyperkalemic patients similarly when given with or without food; unlike prior studies, patients were not required to be taking RAASi. We conducted post hoc analyses to provide the first report of patiromer in patients not taking RAASi. Methods: Hyperkalemic patients received patiromer, 8.
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9

Rosano, Giuseppe MC, Ilaria Spoletini, Cristiana Vitale, and Stefan Agewall. "Hyperkalemia and Renin–Angiotensin–Aldosterone System Inhibitors Dose Therapy in Heart Failure With Reduced Ejection Fraction." Cardiac Failure Review 5, no. 3 (2019): 130–32. http://dx.doi.org/10.15420/cfr.2019.8.2.

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Renin–angiotensin–aldosterone system inhibitors (RAASi) are known to improve outcomes in patients who have heart failure with reduced ejection fraction (HFrEF). To reduce mortality in these patients, RAASi should be uptitrated to the maximally tolerated dose. However, RAASi may also cause hyperkalemia. As a result of this side-effect, doses of RAASi are reduced, discontinued and seldom reinstated. Thus, the therapeutic target needed in these patients is often not reached because of hyperkalemia. Also, submaximal dosing of RAASi may be a result of symptomatic hypotension, syncope, hypoperfusion
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10

Jamison, Robert L. ""Die besten Bissen vom Kuchen". Wilhelm Raabes Erzählwerk: Kontexte, Subtexte, Anschlüsse, and: Wilhelm Raabe: Global Themes—International Perspectives, and: Erkundungen im Überseeischen. Wilhelm Raabe und die Füllung der Welt." Monatshefte 103, no. 1 (2011): 126–31. http://dx.doi.org/10.1353/mon.2011.0029.

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11

van den Belt, Sophie M., Hiddo J. L. Heerspink, Marietta Kirchner, et al. "Discontinuation of RAAS Inhibition in Children with Advanced CKD." Clinical Journal of the American Society of Nephrology 15, no. 5 (2020): 625–32. http://dx.doi.org/10.2215/cjn.09750819.

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Background and objectivesAlthough renin-angiotensin-aldosterone system inhibition (RAASi) is a cornerstone in the treatment of children with CKD, it is sometimes discontinued when kidney function declines. We studied the reasons of RAASi discontinuation and associations between RAASi discontinuation and important risk markers of CKD progression and on eGFR decline in the Cardiovascular Comorbidity in Children with CKD study.Design, setting, participants, &amp; measurementsIn this study, 69 children with CKD (67% male, mean age 13.7 years, mean eGFR 27 ml/min per 1.73 m2) who discontinued RAASi
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12

Hundemer, Gregory L., Robert Talarico, Navdeep Tangri, et al. "Ambulatory Treatments for RAAS Inhibitor–Related Hyperkalemia and the 1-Year Risk of Recurrence." Clinical Journal of the American Society of Nephrology 16, no. 3 (2021): 365–73. http://dx.doi.org/10.2215/cjn.12990820.

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Background and objectiveThe optimal ambulatory management of renin-angiotensin-aldosterone system inhibitor (RAASi)–related hyperkalemia to reduce the risk of recurrence is unknown. We examined the risk of hyperkalemia recurrence on the basis of outpatient pharmacologic changes following an episode of RAASi-related hyperkalemia.DesignWe performed a population-based, retrospective cohort study of older adults (n=49,571; mean age 79 years) who developed hyperkalemia (potassium ≥5.3 mEq/L) while on a RAASi and were grouped as follows: no intervention, RAASi discontinuation, RAASi dose decrease, n
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13

Wang, Angela Yee-Moon. "Optimally managing hyperkalemia in patients with cardiorenal syndrome." Nephrology Dialysis Transplantation 34, Supplement_3 (2019): iii36—iii44. http://dx.doi.org/10.1093/ndt/gfz225.

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Abstract Renin–angiotensin–aldosterone system inhibitors (RAASi) are now a standard treatment in most patients with cardiovascular disease, especially in those with heart failure (HF). The European Society of Cardiology and the American College of Cardiology/American Heart Association gave a Class IA recommendation for the use of RAASi in the treatment of Classes II–IV symptomatic HF with reduced ejection fraction (HFREF), based on their strong clinical benefits of lowering all-cause mortality and HF hospitalizations in these subjects. However, RAASi therapy or adding mineralocorticoid recepto
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14

Chiang, Cho Hung, Cho Han Chiang, YUANPING HSIA, Cho Hsien Chiang, and Her-Shyong Shiah. "The impact of renin-angiotensin-aldosterone system inhibitors on immune checkpoint inhibitor-associated adverse cardiovascular events." Journal of Clinical Oncology 41, no. 16_suppl (2023): 2605. http://dx.doi.org/10.1200/jco.2023.41.16_suppl.2605.

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2605 Background: Immune checkpoint inhibitors (ICIs) are associated with adverse cardiovascular events that impair patient outcomes. Previous observational studies showed that renin-angiotensin-aldosterone system inhibitors (RAASi) may mitigate the cardiotoxicity associated with chemotherapeutic agents. However, the effects of RAASi on ICI-associated adverse cardiovascular events are unknown. Methods: We conducted a 1:1 propensity score-matched cohort study involving ICI-treated patients at two tertiary referral centers in Taiwan. The propensity score matching model includes age, sex, hyperten
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15

Shahil-Feroz, Anam, Haleema Yasmin, Sarah Saleem, Zulfiqar Bhutta, and Emily Seto. "Remote Moderated Usability Testing of a Mobile Phone App for Remote Monitoring of Pregnant Women at High Risk of Preeclampsia in Karachi, Pakistan." Informatics 10, no. 4 (2023): 79. http://dx.doi.org/10.3390/informatics10040079.

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This study assessed the usability of the smartphone app, named “Raabta” from the perspective of pregnant women at high risk of preeclampsia to improve the Raabta app for future implementation. Think-aloud and task-completion techniques were used with a purposive sample of 14 pregnant women at high risk of preeclampsia. The sessions were audio-recorded and later professionally transcribed for thematic analysis. The study generated learnings associated with four themes: improving the clarity of instructions, messaging, and terminology; accessibility for non-tech savvy and illiterate Urdu users;
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16

Simon, Ralf. "Raabes literarische Historik." Jahrbuch der Raabe-Gesellschaft 50, no. 2009 (2009): 7–21. http://dx.doi.org/10.1515/9783484339194.7.

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17

Silva-Cardoso, José, Dulce Brito, João Miguel Frazão, et al. "Management of RAASi-associated hyperkalemia in patients with cardiovascular disease." Heart Failure Reviews 26, no. 4 (2021): 891–96. http://dx.doi.org/10.1007/s10741-020-10069-3.

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AbstractRenin–angiotensin–aldosterone system inhibitors (RAASi) reduce morbidity and mortality in heart failure (HF) with reduced ejection fraction in a dose-dependent manner. They also have a positive impact in other cardiovascular diseases (CVDs). However, RAASi may induce hyperkalemia, a potentially life-threatening disorder. This risk is further increased in those with concomitant chronic kidney disease, diabetes mellitus, and/or in patients with hypertension. Current treatment guidelines recommend maximal RAASi dosing to improve clinical outcomes; however, this is often limited by the dev
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18

Lindinger, Stefan. "Wieland's Frogs, Raabe's Geese: Animals in Christoph Martin Wieland's History of the Abderites and in Wilhelm Raabe's The Geese of Bützow." Kronstädter Beiträge zur germanistischen Forschung 22 (May 20, 2022): 175–92. http://dx.doi.org/10.31926/kbzgf.2022.22.11.

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In diesem Beitrag wird die Rolle von Tieren in zwei intertextuell aufeinander bezogenen Erzählwerken untersucht, in denen jene den Menschen im Sinne einer satirischen Spiegelung gegenübergestellt sind. Die Parallele zur Gesellschaft (in beiden Fällen eine provinzielle Kleinstadt) bildet jeweils ein Tierkollektiv: (quakende) Frösche und (schnatternde) Gänse, auf deren Tradition in Literatur- und Kulturgeschichte zunächst kurz eingegangen wird. Sowohl in Christoph Martin Wielands Geschichte der Abderiten (1774-1780/1781) als auch in Wilhelm Raabes Die Gänse von Bützow (1866/1869) liegt der Schwe
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19

Jones, Sarah L., Maria Johnson, Bronwen Alty, and Marios Adamou. "The Effectiveness of RAADS-R as a Screening Tool for Adult ASD Populations." Autism Research and Treatment 2021 (September 11, 2021): 1–6. http://dx.doi.org/10.1155/2021/9974791.

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Adult referrals to specialist autism spectrum disorder diagnostic services have increased in recent years, placing strain on existing services. It was proposed that the Ritvo Autism Asperger’s Diagnostic Scale could be used as a screening tool, in order to identify and prioritise patients most likely to receive an ASD diagnosis. This study evaluates the validity of the RAADS-R as a screening tool for ASD in an adult population. Retrospective case note analysis was used to evaluate the efficacy of the RAADS-R as a screening tool to predict ASD diagnostic outcomes in 50 service users of a NHS sp
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20

Udell, Jacob A., David A. Morrow, Eugene Braunwald, et al. "Inhibition of the Renin-Angiotensin System Reduces the Rise in Serum Aldosterone in Acute Coronary Syndrome Patients with Preserved Left Ventricular Function: Observations from the AVANT GARDE-TIMI 43 Trial." Clinical Chemistry 59, no. 6 (2013): 959–67. http://dx.doi.org/10.1373/clinchem.2012.199729.

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BACKGROUND Acute coronary syndrome (ACS) activates neurohormonal pathways, including elevations in circulating aldosterone, with deleterious cardiovascular effects. We aimed to determine if early, more complete renin-angiotensin-aldosterone system inhibition (RAASI) in post-ACS patients without ventricular dysfunction or heart failure would result in a graded reduction in aldosterone concentrations. METHODS We performed serial measurement of serum aldosterone within the Aliskiren and Valsartan to Reduce NT-proBNP via Renin-Angiotensin-Aldosterone-System Blockade (AVANT GARDE)–Thrombolysis in M
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21

Ruppelt, Georg. "Paul Raabes letztes Buch." Zeitschrift für Bibliothekswesen und Bibliographie 60, no. 5 (2013): 255–56. http://dx.doi.org/10.3196/186429501360550.

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22

Süselbeck, Jan. "Wilhelm Raabes ›schöne Jüdinnen‹." Zeitschrift für interkulturelle Germanistik 5, no. 1 (2014): 51–68. http://dx.doi.org/10.14361/zig-2014-0105.

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23

Parr, Rolf. "Raabes Effekte des Realen." Jahrbuch der Raabe-Gesellschaft 52, no. 2011 (2011): 21–38. http://dx.doi.org/10.1515/9783110236705.21.

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24

Yang, Ya-Zi, Li-Jun Liu, Su-Fang Shi, et al. "Effects of Hydroxychloroquine on Proteinuria in Immunoglobulin A Nephropathy." American Journal of Nephrology 47, no. 3 (2018): 145–52. http://dx.doi.org/10.1159/000487330.

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Background: Hydroxychloroquine (HCQ) is a well-known immunomodulator that is useful as in the treatment for lupus because of its inhibitory effect on toll-like receptors and cytokines, which are speculated to play a role in the pathogenesis of Immunoglobulin A (IgA) nephropathy (IgAN). However, there was only one study that investigated the effect of HCQ on proteinuria in patients with IgAN. Methods: Ninety patients with IgAN who received HCQ in addition to optimized dosage of renin-angiotensin-aldosterone system inhibitors (RAASi) were recruited for this study, and 90 matched historical contr
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Masanetz, Michael. "Raabe-Rapporte." Jahrbuch der Raabe-Gesellschaft 44, no. 1 (2003): 162–68. http://dx.doi.org/10.1515/9783484339033.162.

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Schwarz, Robert, and Thomas Strittmatter. "Raabe Baikal." World Literature Today 65, no. 4 (1991): 698. http://dx.doi.org/10.2307/40147678.

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Lotz, Niklas, and Katharina Marguc. "Raabe-Bibliographie." Jahrbuch der Raabe-Gesellschaft 64, no. 1 (2024): 362–98. https://doi.org/10.1515/raabe-2023-0026.

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28

Denkler, Horst. "PANIER AUFWERFEN FÜR RAABE. Zur Geschichte der ‚Raabe-Pflege‛ im Bannkreis der Raabe-Gesellschaft." Jahrbuch der Raabe-Gesellschaft (1987) 28 (January 31, 1987): 11–23. http://dx.doi.org/10.1515/9783110243765.11.

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29

Kohsaka, Shun, Suguru Okami, Naru Morita, and Toshitaka Yajima. "Risk–Benefit Balance of Renin–Angiotensin–Aldosterone Inhibitor Cessation in Heart Failure Patients with Hyperkalemia." Journal of Clinical Medicine 11, no. 19 (2022): 5828. http://dx.doi.org/10.3390/jcm11195828.

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Background: Whether to continue renin–angiotensin–aldosterone system inhibitor (RAASi) therapy in patients with hyperkalemia remains a clinical challenge, particularly in patients with heart failure (HF), where RAASis remain the cornerstone of treatment. We investigated the incidence of dose reduction or the cessation of RAASis and evaluated the threshold of serum potassium at which cessation alters the risk–benefit balance. Methods: This retrospective analysis of a Japanese nationwide claims database investigated treatment patterns of RAASis over 12 months after the initial hyperkalemic episo
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Skorokhodov, Ivan V., Ksenia P. Radygina, Elena Y. Skorokhodova, Svetlana P. Firsova, Galina V. Portnova, and Anton A. Varlamov. "Development and Initial Validation of the Russian Version of the RAADS-14: A Self-Report Questionnaire to Assess Autistic Traits." European Journal of Investigation in Health, Psychology and Education 13, no. 11 (2023): 2724–35. http://dx.doi.org/10.3390/ejihpe13110188.

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Autism is a relatively common neurodevelopmental condition that affects social communication and behavior, affecting the overall quality of life. The prevalence of autism is constantly increasing, but timely diagnosis allows for effective treatment. The aim of our research was to construct a Russian version of the RAADS-14, a brief self-report questionnaire originally designed for autism screening, and to perform its initial validation to provide a reference point in developing autism self-assessment tools for the Russian-speaking population. Psychometric properties of the RAADS-14 Rus were ev
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Schnaubelt, Sebastian, Anna Jakobljevich, Roman Brock, et al. "The Relation of Angiotensin-Converting Enzyme 2, Renin-Angiotensin-Aldosterone System Inhibitors, and Arterial Stiffness in Acute COVID-19 Emergency Department Patients—A Prospective Observational Study." Journal of Clinical Medicine 14, no. 7 (2025): 2233. https://doi.org/10.3390/jcm14072233.

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Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing coronavirus disease 2019 (COVID-19) can damage the endothelium and increase arterial stiffness, potentially leading to adverse cardiovascular events. In parallel, systemic inflammation in COVID-19 also impacts endothelial function. Angiotensin-converting enzyme 2 (ACE2) promotes vasodilation and anti-inflammatory effects, but also facilitates SARS-CoV-2 entry into human cells. Thus, concerns have been raised about the use of RAAS inhibitors (RAASi) in COVID-19 patients due to potential ACE2 upregulation. However,
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Halima, Halima, Laelah Azizah, and Fauziyah Bachtiar. "Efektivitas Metode Mimicry Memorization dalam Meningkatkan Penguasaan Kosa Kata (Mufrodat) Bahasa Arab Siswa Kelas IX Smp Islam Ar-Raafi’ Kota Makassar." Al-Fashahah: Journal of Arabic Education, Linguistics, and Literature 3, no. 1 (2023): 69. http://dx.doi.org/10.59562/al-fashahah.v3i1.46701.

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Penelitian ini adalah penelitian Nonequivalent Control Group Design yang bertujuan untuk mengetahui efektivitas penggunaan metode mimicry memorization dalam meningkatkan penguasaan kosakata (mufrodat) Bahasa arab siswa kelas IX SMP Islam Ar-Raafi’ kota Makassar. Variabel bebas dalam penelitian ini adalah penggunaan metode mimicry memorization, sedangkan variabel terikatnya adalah penguasaan kosakata (mufrodat). Populasi dalam penelitian ini adalah seluruh siswa kelas IX SMP Islam Ar-Raafi’ yang berjumlah 40 orang siswa, Adapun sampel dalam penelitian ini adalah seluruh siswa kelas IX SMP Islam
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Sahu, Ananta Basudev, Jatin Tiwari, Prasannakumar P. N., and R. N. Mohanty. "Bridging vision gaps: a comprehensive study of the RAAHI programme for improving truckers' eye health in India." International Journal Of Community Medicine And Public Health 11, no. 5 (2024): 1942–48. http://dx.doi.org/10.18203/2394-6040.ijcmph20241192.

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Background: Visual impairment presents a significant public health concern globally, with a notable impact on individuals' quality of life. Despite efforts to address this issue, unmet eye health needs persist, particularly in vulnerable populations such as truck drivers in low and middle-income countries like India. The RAAHI (National truckers eye health programme) initiative aims to fill this gap by providing essential eye care services in India. Methods: This research manuscript delves into the journey of the RAAHI programme from 2017 to 2022, assessing its achievements, challenges, and le
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"Trichodina raabei." CABI Compendium CABI Compendium (January 7, 2022). http://dx.doi.org/10.1079/cabicompendium.60559.

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Shahil-Feroz, Anam, Andaz Riaz, Haleema Yasmin, Sarah Saleem, Zulfiqar Bhutta, and Emily Seto. "Perceived barriers and facilitators of implementing a sustained smartphone-based telemonitoring program for pregnant women at high-risk for pre-eclampsia in the public and private sectors in Pakistan." DIGITAL HEALTH 10 (January 2024). https://doi.org/10.1177/20552076241292682.

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Background In Pakistan, a smartphone-based telemonitoring (TM) program (Raabta) has been designed to support pregnant women with high risk for preeclampsia (HRPE) in Pakistan. However, implementing TM interventions is often challenging, particularly in low-resource settings, given the complexity of healthcare environments and variations in public and private health sectors. This study explores the potential barriers and facilitators for a sustained implementation of the Raabta program in public and private sector hospitals in Pakistan. Methods Using a qualitative description design, 57 semi-st
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Azmal Ali, Syed, Ashish Kumar Singh, Sudhir K. Tomar, and Pradip Behare. "Genome Sequence of Lacticaseibacillus rhamnosus Strain NCDC610, Isolated from a Traditional Cereal-Based Fermented Milk Product (Raabadi)." Microbiology Resource Announcements 10, no. 45 (2021). http://dx.doi.org/10.1128/mra.00672-21.

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We announce the draft genome sequence of Lacticaseibacillus rhamnosus NCDC610, an isolate from an Indian traditional cereal-based fermented milk product (Raabadi). The genome size of Lacticaseibacillus rhamnosus NCDC610 is 2.91 Mb with the assembled sequence, and the genome consists of 67 contigs.
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Agiro, Abiy, Alpesh Amin, Fan Mu, et al. "Abstract 10620: Real-World Use of Renin-Angiotensin-Aldosterone System Inhibitors in Patients with Heart Failure and Hypertension Initiating Sodium Zirconium Cyclosilicate: The Optimize Study." Circulation 144, Suppl_1 (2021). http://dx.doi.org/10.1161/circ.144.suppl_1.10620.

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Introduction: Renin-angiotensin-aldosterone system inhibitors (RAASis) in patients (pts) with heart failure (HF) and hypertension (HTN) are associated with a reduced risk of death or disease progression, but increased risk of hyperkalemia (HK) with RAASis may lead to discontinuation and reduced benefit. This real-world study evaluated RAASi use patterns in pts who initiated sodium zirconium cyclosilicate (SZC) for HK. Methods: Adult (≥18 years) outpatients who initiated SZC (index date) while on RAASis were retrospectively identified from a large US claims database (Jan 2018 to Jun 2020). Anal
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Lee, Seung Hun, Tae-Min Rhee, Doosup Shin, et al. "Prognosis after discontinuing renin angiotensin aldosterone system inhibitor for heart failure with restored ejection fraction after acute myocardial infarction." Scientific Reports 13, no. 1 (2023). http://dx.doi.org/10.1038/s41598-023-30700-1.

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AbstractPrognostic effect of discontinuing renin–angiotensin–aldosterone-system-inhibitor (RAASi) for patients with heart failure (HF) after acute myocardial infarction (AMI) whose left ventricular (LV) systolic function was restored during follow-up is unknown. To investigate the outcome after discontinuing RAASi in post-AMI HF patients with restored LV ejection fraction (EF). Of 13,104 consecutive patients from the nationwide, multicenter, and prospective Korea Acute Myocardial Infarction-National Institutes of Health (KAMIR-NIH) registry, HF patients with baseline LVEF &lt; 50% that was res
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Gant, C. M., M. M. Oosterwijk, S. H. Binnenmars, et al. "Use of maximal dosage renin-angiotensin-aldosterone system inhibitors in a real life population of complicated type 2 diabetes – contraindications and opportunities." BMC Nephrology 24, no. 1 (2023). http://dx.doi.org/10.1186/s12882-023-03205-2.

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Abstract Objective Pharmacological inhibition of the renin-angiotensin-aldosterone-system (RAASi) is the cornerstone of hypertension treatment, renoprotection and secondary prevention of cardiovascular disease in patients with type 2 diabetes. Although there is a dose-dependent effect of RAASi with optimum protection when using maximal dose, little is known on actual use of maximal dosage RAASi in clinical practice. Here we investigate prevalence of maximal dosage RAASi, and contraindications for, optimizing RAASi dosage, in patients with complicated type 2 diabetes in a real-life clinical set
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January, Spenser E., Julie Hubbard, Keith A. Fester, et al. "Impact of Angiotensin Blockade on Development of Chronic Lung Allograft Dysfunction." Journal of Pharmacy Practice, November 3, 2023. http://dx.doi.org/10.1177/08971900231213699.

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Background: The renin-angiotensin-aldosterone system (RAAS) is responsible for a multitude of physiological functions, including immunological effects such as promotion of TGF-β and upregulation of IL-6 and IL-8 which are also implicated in the development of chronic lung allograft dysfunction (CLAD). Blockade of the RAAS pathway in pre-clinical models has demonstrated a decrease in these cytokines and pulmonary neutrophil recruitment. Objective: This study sought to evaluate whether use of RAAS inhibitor (RAASi) in lung transplant recipients impacted CLAD-free survival. Methods: In this retro
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Diaz Acevedo, Jesus, Greilys Lazcano, Mariana Soto, et al. "Abstract 10533: Cardiorenal Effects of Sglt2 Inhibitors and Finerenone in Type 2 Diabetes and Chronic Kidney Disease. Single, Dual or Triple Therapy? A Network Meta-Analysis." Circulation 146, Suppl_1 (2022). http://dx.doi.org/10.1161/circ.146.suppl_1.10533.

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Introduction: Sodium-glucose co-transporter 2 inhibitors (SGLT2i) and a non-steroidal mineralocorticoid receptor antagonist, finerenone, have demonstrated their efficacy in slowing CKD progression and preventing cardiovascular events in diabetic kidney disease (DKD). However, it is unclear which one is more effective or whether a combination could provide additional benefits. Methods: A network meta-analysis (NMA) was conducted on RCTs of DKD, which evaluated the cardiovascular and renal effects of SGLT2i and finerenone. The primary outcome was a cardiorenal outcome composed of GFR decline as
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Kohsaka, Shun, Tomoko Ishizu, Suguru Okami, Takashi Kikuchi, Rashad Mogalli, and Toshitaka Yajima. "Abstract 13365: Risk-benefit Evaluation in Cessation of Renin-angiotensin-aldosterone Inhibitors in Hyperkalemic Heart Failure Patients: A Japanese Real-world Study From Nationwide Administrative Database." Circulation 142, Suppl_3 (2020). http://dx.doi.org/10.1161/circ.142.suppl_3.13365.

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Introduction: Hyperkalemia (HK) is frequently encountered in patients treated with renin-angiotensin-aldosterone system inhibitors (RAASi), and is associated with increased mortality in heart failure (HF). While cessation of RAASi is considered an option in HK patients, the serum potassium (sK) threshold for RAASi cessation in HF patients remains unclear . Herein, we sought to assess the impact of RAASi cessation or continuation on risk-benefit balance of hyperkalemic HF patients using propensity score (PS)-matched and cubic spline regression analysis in a nationwide administrative database. M
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Alcoberro, L., S. Jimenez-Marrero, M. Cainzos-Achirica, et al. "Factors associated to renin-angiotensin-aldosterone system inhibitors discontinuation or down-titration due to hyperkalaemia in patients with chronic cardiovascular conditions." European Heart Journal 43, Supplement_2 (2022). http://dx.doi.org/10.1093/eurheartj/ehac544.2694.

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Abstract Background/Introduction The renin-angiotensin-aldosterone system inhibitors (RAASI) are one of the keystones of the medical treatment in chronic cardiovascular disorders and have shown improvements in clinical outcomes in many clinical trials. Hyperkalaemia is a well-defined non-desirable effect of RAASI that occasionally forces to interrupt these medications. That enforced RAASI discontinuation or down-titration due to hyperkalaemia may have adverse prognostic consequences. Purpose Describe the demographical, clinical and pharmacological variables associated to a higher risk of RAASI
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Agiro, Abiy, Jingyi Chen, Ali Greatsinger, et al. "#1481 Renin-angiotensin-aldosterone system inhibitor (RAASi) optimisation after initiating outpatient SZC therapy: the GALVANIZE RAASi real-world study." Nephrology Dialysis Transplantation 39, Supplement_1 (2024). http://dx.doi.org/10.1093/ndt/gfae069.712.

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Abstract Background and Aims Hyperkalaemia often occurs in patients with comorbidities that are treated with renin-angiotensin-aldosterone system inhibitors (RAASi), e.g., chronic kidney disease (CKD), heart failure or resistant hypertension. However, RAASi use can exacerbate hyperkalaemia. The GALVANIZE RAASi real-world study evaluated RAASi dose optimisation or maximisation following initiation of sodium zirconium cyclosilicate (SZC) therapy in the outpatient setting. Method A large US insurance claims database (from HealthVerity), spanning July 2018–December 2022, was used to identify adult
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Packham, David, Philip Lavin, Pablo Pergola, et al. "P0189SODIUM ZIRCONIUM CYCLOSILICATE CORRECTS HYPERKALAEMIA WITHIN 72 HOURS AMONG OUTPATIENTS WITH SEVERE HYPERKALAEMIA (BASELINE SERUM POTASSIUM ≥6 MMOL/L) REGARDLESS OF RENAL FUNCTION LEVEL OR RAASI USE: POST HOC SUBGROUP ANALYSIS OF A PHASE 3 TRIAL." Nephrology Dialysis Transplantation 35, Supplement_3 (2020). http://dx.doi.org/10.1093/ndt/gfaa142.p0189.

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Abstract Background and Aims Most patients with severe hyperkalaemia are treated in hospital settings and are often receiving renin–angiotensin–aldosterone system inhibitors (RAASi) and/or have chronic kidney disease. Sodium zirconium cyclosilicate (SZC; formerly ZS-9) is an orally-administered, non-absorbable, inorganic, selective potassium (K+) binder for the treatment of adults with hyperkalaemia. SZC entraps K+ throughout the gastrointestinal tract in exchange for hydrogen and sodium ions and significantly reduces serum K+ within one hour of administration. We report time to achievement of
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Svensson, Maria K., Toyoaki Murohara, Eva Lesén, et al. "Hyperkalaemia-related reduction of RAASi treatment associates with more subsequent inpatient care." Nephrology Dialysis Transplantation, January 22, 2024. http://dx.doi.org/10.1093/ndt/gfae016.

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Abstract Background Hyperkalaemia is a barrier to achieving optimal, guideline-directed treatment with renin-angiotensin-aldosterone system inhibitors (RAASi) in patients with chronic kidney disease (CKD) and/or heart failure (HF). This study describes the association between hyperkalaemia-related RAASi treatment reduction and number of hospitalized days in patients with CKD and/or HF in Sweden and Japan. Methods Using data from health registers and hospital medical records, patients with CKD and/or HF currently receiving RAASi who experienced an index hyperkalaemia episode were identified and
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Varga, Mária. "Familiennamen deutscher Herkunft in der Raabau (Rábaköz)/Westungarn." Namenkundliche Informationen, May 1, 2011, 124–44. http://dx.doi.org/10.58938/ni469.

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Im Nachfolgenden werden einige Ausschnitt e aus den Untersuchungen der historischen Familiennamen in der Raabau angeführt. Die Raabau liegt in Nordwest-Transdanubien in Ungarn. Das Zentrum des Forschungsgebietes ist die Kleinstadt Kapuvár. Im 18. Jahrhundert befanden sich hier kleine Siedlungen mit ungefähr je Tausend Einwohnern. In diesem Gebiet wurde Personennamenforschung in 26 Siedlungen durchgeführt. Die Zusammensetz ung der Bevölkerung zeichnet sich durch ihre Homogenität aus. Die Bewohner der Raabau gehörten der katholischen Kirche an, und nach ihrer Herkunft waren sie Ungarn. Diese let
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Westermann, Lukas, Janis M. Nolde, Johannes Wiegel, Georg Büchler, Frederic Arnold, and Thomas Welte. "Impact of Renin-Angiotensin-Aldosterone System Inhibition on Advanced Chronic Kidney Disease Progression - a Retrospective Observational Study." American Journal of Nephrology, February 26, 2025, 1–15. https://doi.org/10.1159/000543487.

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Introduction: Maintaining renin-angiotensin-aldosterone system inhibition (RAASi) in advanced chronic kidney disease (CKD) to delay CKD progression is still controversial. This is due to potential side effects associated with RAASi, such as a decline in glomerular filtration rate (GFR) and hyperkalemia. This study aims to examine the effect of RAASi on progression of advanced CKD to kidney failure (eGFR &lt;15 ml/min/1.73 m2, CKD stage 5) in a real-life outpatient cohort. Methods: This single-center retrospective observational study presents data from 954 individuals with advanced CKD (estimat
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Svensson, Maria K., Michael Fischereder, Paul R. Kalra, et al. "Hyperkalemia-Related RAASi Reduction and Estimated Number Needed to Treat to Avoid a First Hospitalization by Maintaining RAASi." Kidney360, August 21, 2024. http://dx.doi.org/10.34067/kid.0000000000000561.

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Background: Renin-angiotensin-aldosterone system inhibitor (RAASi) therapy provides cardiorenal protection but is often down-titrated or discontinued following a hyperkalemia episode. This observational study describes the extent of hyperkalemia-related RAASi reduction in patients with chronic kidney disease (CKD) and/or heart failure (HF), and estimates the number needed to treat (NNT) to avoid a first hospitalization if RAASi had been maintained at the prior dose. Methods: Healthcare registers and claims data from Germany, Spain, Sweden, and the UK were used to identify non-dialysis patients
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Ellis, Hugh Logan, Mohammad Al-Agil, Philip A. Kelly, James Teo, Claire Sharpe, and Martin B. Whyte. "Impact of hyperkalaemia on renin–angiotensin–aldosterone (RAAS) inhibitor reduction or withdrawal following hospitalisation." Clinical and Experimental Medicine 25, no. 1 (2024). https://doi.org/10.1007/s10238-024-01531-9.

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Abstract Background Inhibitors of the renin–angiotensin–aldosterone system (RAAS), such as ACE inhibitors (ACEi), angiotensin-II receptor blockers and mineralocorticoid receptor antagonists, reduce morbidity and mortality in hypertension, congestive heart failure and chronic kidney disease. However, their use can lead to hyperkalaemia. We examined the proportions of RAAS inhibitor (RAASi) reduction or withdrawal, across GFR strata, following hospitalisation and the effect on patient mortality. Methods This was a retrospective cohort study of adult patients hospitalised from 1 January2017 to 31
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