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Relevant bibliographies by topics / Rabbit animal model

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Academic literature on the topic 'Rabbit animal model'

Author: Grafiati

Published: 4 June 2021

Last updated: 3 February 2022

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Journal articles on the topic "Rabbit animal model"

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Calasans-Maia, Mônica Diuana, Maria Lucia Monteiro, Fábio Oliveira Áscoli, and José Mauro Granjeiro. "The rabbit as an animal model for experimental surgery." Acta Cirurgica Brasileira 24, no. 4 (2009): 325–28. http://dx.doi.org/10.1590/s0102-86502009000400014.

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The white New Zealand rabbit (Oryctolagus cuniculus) is frequently used as a model for in vivo studies. However, information on precautions when using this animal as an experimental model is limited. This review of the literature covers the gamut from the selection of the animal model all the way to its death, and describes procedures for transporting, raising, breeding, housing, administering anesthesia and handling so as to rationalize the utilization of this species while exploiting its unique characteristics. Based upon the literature and our own experience with white New Zealand rabbits,

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Gugołek, Andrzej, and Dorota Kowalska. "Animal Fats in Rabbit Feeding – A Review." Annals of Animal Science 20, no. 4 (2020): 1185–215. http://dx.doi.org/10.2478/aoas-2020-0091.

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Abstract The purpose of this article is to overview the history of feeding rabbits with different types of animal fats, and to discuss their effects on rabbit performance and quality of their products. Other aspects of the inclusion of various animal fats in rabbit diets are also described. This article is based on the analysis of relevant scientific literature and presents animal fats fed to rabbits, such as beef tallow, butter, pork lard, poultry fat, fish oil, krill oil, oil extracted from insect larvae, mixtures of various animal fats, and mixtures of animal and vegetable fats. The reporte

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Miller, Andrew J., Jacob Tulipan, Mark Wang, Pedro Beredjiklian, Andrzej Fertala, and Michael Rivlin. "A PERIPHERAL NERVE INJURY MODEL UTILIZING A SIMPLE TISSUE SPARING APPROACH TO THE RABBIT SCIATIC NERVE." Journal of Musculoskeletal Research 21, no. 01 (2018): 1850002. http://dx.doi.org/10.1142/s0218957718500021.

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Background & Aims: Peripheral nerve injury models require a reproducible surgical technique that provides a simple and extensile peripheral nerve exposure. We present a muscle sparing apprach to the sciatic nerve in a rabbit model. A combination of general anestheia, sedative and perioperative analgesics was given to minimize animal discomfort. Methods: A posterior lateral dissection of the rabbit hind leg was performed to expose the proximal sciatic nerve. This facilitated an extensile dissection of both the proximal and distal sciatic nerve. Results: The described dissection is atraumati

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Stahnke, T., S. Siewert, E. Walther, et al. "Adopting oculopressure tonometry as a transient in vivo rabbit glaucoma model." Current Directions in Biomedical Engineering 1, no. 1 (2015): 127–30. http://dx.doi.org/10.1515/cdbme-2015-0033.

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AbstractGlaucoma represents a group of eye disorders partly related to raised intraocular pressure (IOP) leading to progressive optic nerve damage resulting in impaired vision and possibly blindness. To assess the suitability of new IOP lowering therapeutic strategies, such as the implantation of glaucoma drainage devices, appropriate animal models have to be used. Currently, a number of rodent glaucoma models are available [1], however, especially for surgical interventions rodent eyes are too small. Rabbits are much more suitable with respect to dimension. Unfortunately, rabbit glaucoma mode

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Harvey, Stephen B., Nancy M. Cladel, Lynn R. Budgeon, et al. "Rabbit Genital Tissue Is Susceptible to Infection by Rabbit Oral Papillomavirus: an Animal Model for a Genital Tissue-Targeting Papillomavirus." Journal of Virology 72, no. 6 (1998): 5239–44. http://dx.doi.org/10.1128/jvi.72.6.5239-5244.1998.

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ABSTRACT Rabbit oral papillomavirus (ROPV) is a mucosatropic papillomavirus which naturally infects oral mucosal sites of domestic rabbits. In this study, we tested the hypothesis that rabbit genital mucosa is also susceptible to ROPV infection by using the athymic mouse xenograft system and adult immunocompetent rabbits. Subrenal xenografts of ROPV-infected rabbit vulvar and penile sheath tissues were strongly positive for ROPV infection by histologic, in situ hybridization, and Southern analyses. Direct inoculation of adult rabbit penises with infectious ROPV produced small raised lesions of

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Yang, Shuo, Jie Chen, Yingmo Shen, Minggang Wang, Zhenyu Zou, and Cuihong Jin. "Establishment of a Rabbit Model of Giant Abdominal Wall Hernia." Surgical Innovation 26, no. 3 (2018): 376–80. http://dx.doi.org/10.1177/1553350618814090.

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Purpose. Animal models play an important role in abdominal wall hernia research. However, there is still no standard animal models for abdominal wall hernia. This study aimed to introduce a novel rabbit model of giant abdominal wall hernia. Methods. Sixteen 1-year-old New Zealand rabbits weighing 3 to 5 kg were used. After general anesthesia, a 5-cm longitudinal incision was made 2 cm lateral to the ventral midline, and a full-thickness laparotomy incision was made en bloc including the peritoneum (except skin). A full-thickness defect of the abdominal wall with a diameter of 3 cm was created.

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Lambert, R. K., R. Ramchandani, X. Shen, S. J. Gunst, and R. S. Tepper. "Computational model of airway narrowing: mature vs. immature rabbit." Journal of Applied Physiology 93, no. 2 (2002): 611–19. http://dx.doi.org/10.1152/japplphysiol.00063.2002.

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Immature rabbits have greater maximal airway narrowing and greater maximal fold increases in airway resistance during bronchoconstriction than mature animals. We have previously demonstrated that excised immature rabbit lungs have more distensible airways, a lower shear modulus, and structural differences in the relative composition and thickness of anatomically similar airways. In the present study, we incorporated anatomic and physiological data for mature and immature rabbits into a computational model of airway narrowing. We then investigated the relative importance of maturational differe

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Babar, Abdul Mannan, and Abdul Hannan Nagi. "KELOID." Professional Medical Journal 23, no. 09 (2016): 1157–62. http://dx.doi.org/10.29309/tpmj/2016.23.09.2479.

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Keloids and hypertrophic scars are basically an overabundance of fibrosis in cutaneous healing process. Unfortunately, keloids are only found in human beings. So far no successful animal model of keloid has been reported. Objectives: To produce an animal model of keloid. Main Outcome Measure: Animal model of keloid. Design: Prospective quasiexperimental trial. Setting: Department of Pathology and Experimental Research Laboratory, University of Health Sciences, Lahore, Pakistan. Duration: One year. Sample Size: Twelve albino animals i.e. three mice, three rats, three Guinea pigs, and three rabb

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Kurniawati, Eighty M., Tri HS Hadi, Nur AR Widiatmoko, et al. "New vesicovaginal fistula formation in a rabbit model." Majalah Obstetri & Ginekologi 27, no. 3 (2020): 114. http://dx.doi.org/10.20473/mog.v27i32019.114-118.

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Objective: To create an animal model of vesicovaginal fistula as a modality to develop therapy.Material and Methods: This study was an preliminary experimental study to create new fistula vesicovaginal formation in a rabbit model. Six female New Zealand white rabbits of Stem Cell Research and Development Center of Universitas Airlangga were used in this study and were divided into 3 groups in which there were 2 rabbits in each group. Vesicovaginal fistula formation was performed through laparotomy surgery. After the abdomen is opened, the Nasogastric tube is inserted vaginally into the anterio

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Verbicaro, Thalyta, Allan Fernando Giovanini, Joao Cesar Zielak, Flares Baratto Filho, Melissa Rodrigues de Araujo, and Tatiana Miranda Deliberador. "Osteocalcin Immunohistochemical Expression During Repair of Critical-Sized Bone Defects Treated with Subcutaneous Adipose Tissue in Rat and Rabbit Animal Model." Brazilian Dental Journal 24, no. 6 (2013): 559–64. http://dx.doi.org/10.1590/0103-6440201302362.

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The aim of this study was to evaluate the osteocalcin immunoexpression during the bone repair treated with subcutaneous adipose tissue in rats and rabbits. Fourteen rats and 14 rabbits were used in the study. A critical-sized calvarial defect was created in each animal. The animals were divided into 4 experimental groups: RC (rat control), RbC (rabbit control), RAT (rat adipose tissue), RbAT (rabbit adipose tissue). In the groups RC and RbC the defect was filled with a blood clot. In groups RAT and RbAT, the defect was filled with macerated subcutaneous adipose tissue. The euthanasia was perfo

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Dissertations / Theses on the topic "Rabbit animal model"

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Xi, Jin [Verfasser], and Thomas [Akademischer Betreuer] Iftner. "An Out-bred Animal Model of Cottontail Rabbit Papillomavirus Latent Infection / Jin Xi ; Betreuer: Thomas Iftner." Tübingen : Universitätsbibliothek Tübingen, 2019. http://d-nb.info/1197610812/34.

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Stewart, Kenneth J. "Morphological and biomechanical effects of distraction rate and Insulin-like Growth Factor-1 in distraction osteogenesis of the rabbit mandible." Thesis, University of Aberdeen, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.297465.

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The effects of the rate of distraction and of local infusion of IGF-1 upon bone deposition during mandibular distraction osteogenesis was studied in a rabbit model. Five groups of rabbits were studied. All rabbits, except sham operated controls, underwent distraction to 15 mm. The variables studied were the rate of distraction (0.5 mm twice a day versus 1.5 mm twice a day) and the effects of local IGF-1 infusion via osmotic infusion pumps. Analysis by DEXA scanning and three point bending 28 days after the end of distraction demonstrated no difference in density or strength of bone between the

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Yehia, Ali. "Wenckebach rhythms and [1:1<->2:1] bistability in single rabbit ventricular cells and in a ventricular ionic model." Thesis, McGill University, 1999. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=36738.

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Stimulating a rabbit ventricular cell with a train of current pulses at a long basic cycle length (BCL) and high pulse amplitude (PA) leads to a 1:1 rhythm, where each injected pulse generates an action potential. With a fixed BCL (BCL = 300 ms at 34--36°C and BCL = 1000 ms at 22--24°C), as PA is decreased, there is a transition from 1:1 rhythm to Wenckebach rhythms. These rhythms are characterized by a beat-to-beat increment in latency and action potential duration (APD) culminating in a skipped beat. Using voltage and action potential clamp, as well as a specific channel blocker, I show that

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Haynes, Rashade Ameir Hakim II. "Studies of the early immunological and virological events following Human T Lymphotropic Virus Type 1 infection in the rabbit model." The Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=osu1243527169.

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Oliveira, Ivanilson Alves de. "Desenvolvimento de novo modelo experimental de aneurisma sacular mediante a incubação intra-arterial de papaína em coelhos (Oryctolagus cuniculus)." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/5/5151/tde-24112010-173937/.

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INTRODUÇÃO: O modelo eslastase-induzido de aneurismas tem se destacado, nos últimos anos, porque simula as características geométricas dos aneurismas intracranianos humanos. A elastase destrói as fibras elásticas e dilata as artérias. A papaína é uma enzima que ainda não foi usada com esta finalidade. Os objetivos deste estudo foram determinar se a papaína produz aneurismas saculares em coelhos, e comparar suas características macroscópicas e histológicas com as dos aneurismas elastase-induzidos. MÉTODO: Dezoito coelhos brancos Nova Zelândia (1,9-3,2 kg) foram divididos em 3 grupos: I- elastas

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Zhu, Yinghua, and 朱穎華. "Establishment of osteolysis model in rabbit and evaluation of bisphosphonate intervention." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2004. http://hub.hku.hk/bib/B31246369.

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Meirelles, Rafael Panisi de Campos [UNIFESP]. "Modelo Experimental de Radiodermatite em Coelhos." Universidade Federal de São Paulo (UNIFESP), 2015. http://repositorio.unifesp.br/handle/11600/39335.

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Vuckovic, Aline. "Prenatal modulation of the developing lung in congenital diaphragmatic hernia: functional, morphological, and biological consequences for the neonatal lung." Doctoral thesis, Universite Libre de Bruxelles, 2016. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/228906.

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INTRODUCTION. Congenital diaphragmatic hernia (CDH) combines a congenital malformation of the diaphragm with lung hypoplasia, leading to severe respiratory distress and intractable pulmonary hypertension of the newborn. Despite advances in prenatal diagnosis and neonatal intensive care, CDH is associated with high mortality and devastating morbidities. In the absence of curative treatment, numerous prenatal therapies have been used experimentally with varying success. So far, only fetal tracheal occlusion has been tested in clinical trials, but the consequences for the human lung are poorly kn

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Zuccon, Alexandre. "Análise do ligamento redondo na instabilidade não traumática do quadril estudo experimental em coelhos /." Universidade Estadual Paulista (UNESP), 2018. http://hdl.handle.net/11449/153010.

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Submitted by ALEXANDRE ZUCCON null (alexandre.zuccon@gmail.com) on 2018-03-13T18:43:03Z No. of bitstreams: 1 ZucconA_tese.pdf: 2380193 bytes, checksum: edc82ec834fe6990d8e85db3314e4696 (MD5)<br>Approved for entry into archive by Luciana Pizzani null (luciana@btu.unesp.br) on 2018-03-13T20:34:25Z (GMT) No. of bitstreams: 1 zuccon_a_dr_bot.pdf: 2380193 bytes, checksum: edc82ec834fe6990d8e85db3314e4696 (MD5)<br>Made available in DSpace on 2018-03-13T20:34:25Z (GMT). No. of bitstreams: 1 zuccon_a_dr_bot.pdf: 2380193 bytes, checksum: edc82ec834fe6990d8e85db3314e4696 (MD5) Previous issue date: 201

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Leung, Hon-bong. "Consequence of paraspinal muscle after posterior lumbar spinal fusion the histology and electromyography findings in a rabbit model /." Click to view the E-thesis via HKUTO, 2003. http://sunzi.lib.hku.hk/hkuto/record/B31971179.

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Books on the topic "Rabbit animal model"

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The laboratory rabbit, guinea pig, hamster, and other rodents. Academic Press/Elsevier, 2012.

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Allen, Arthur W. Habitat suitability index models: Swamp rabbit. Western Energy and Land Use Team, Division of Biological Services, Research and Development, Fish and Wildlife Service, U.S. Dept. of the Interior, 1985.

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Allen, Arthur W. Habitat suitability index models. National Ecology Center, Fish and Wildlife Service, U.S. Dept. of the Interior, 1987.

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Allen, Arthur W. Habitat suitability index models. National Ecology Center, Fish and Wildlife Service, U.S. Dept. of the Interior, 1987.

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Allen, Arthur W. Habitat suitability index models: Mink. National Ecology Center, Division of Wildlife and Contaminant Research, Fish and Wildlife Service, U.S. Dept. of the Interior, 1986.

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Allen, Arthur W. Habitat suitability index models: Gray partridge. Western Energy and Land Use Team, Division of Biological Services, Research and Development, Fish and Wildlife Service, U.S. Dept. of the Interior, 1985.

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Allen, Arthur W. Habitat suitability index models: American coot. Western Energy and Land Use Team, Division of Biological Services, Research and Development, Fish and Wildlife Service, U.S. Dept. of the Interior, 1985.

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Allen, Arthur W. Habitat suitability index models: Moose, Lake Superior region. U.S. Dept. of the Interior, Fish and Wildlife Service, Research and Development, 1988.

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Allen, Arthur W. Habitat suitability index models: Mallard (winter habitat, lower Mississippi Valley). National Ecology Center, Division of Wildlife and Contaminant Research, Fish and Wildlife Service, U.S. Dept. of the Interior, 1987.

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Pathogenesis of Human Pulmonary Tuberculosis: Insights from the Rabbit Model. ASM Press, 2006.

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Book chapters on the topic "Rabbit animal model"

1

Lukáčová, Nadežda, Jaroslav Pavel, and Ján Gálik. "Spinal Cord Injury: The Rabbit Model." In Animal Models of Spinal Cord Repair. Humana Press, 2012. http://dx.doi.org/10.1007/978-1-62703-197-4_7.

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Ballabh, Praveen. "Preterm Rabbit Model of Glycerol-Induced Intraventricular Hemorrhage." In Animal Models of Neurodevelopmental Disorders. Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-2709-8_4.

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Luo, Kehuan, Jessica Baker, Matthew Derrick, and Sidhartha Tan. "The Rabbit as a Model of Cerebral Palsy." In Animal Models of Neurodevelopmental Disorders. Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-2709-8_9.

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Korte, Gary E., Ayala Pollack, and Paul Henkind. "Animal Model of RPE-Choriocapillaris Interactions: Sodium Iodate Retinopathy in the Rabbit." In Documenta Ophthalmologica Proceedings Series. Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-009-3337-8_67.

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Butler, D. G. "Rabbits and Severe Combined Immunodeficient (SCID) Mice as Animal Models for Mycobacteria in Crohn’s Disease." In Is Crohn’s Disease a Mycobacterial Disease? Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-011-1830-9_6.

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Etheridge, M. E. "Rabbit Model of Shigellosis." In Handbook of Animal Models of Infection. Elsevier, 1999. http://dx.doi.org/10.1016/b978-012775390-4/50167-6.

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Motschmann, M., and W. Behrens-Baumann. "Rabbit Model of Bacterial Conjunctivitis." In Handbook of Animal Models of Infection. Elsevier, 1999. http://dx.doi.org/10.1016/b978-012775390-4/50179-2.

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Lefort, A., and B. Fantin. "Rabbit Model of Bacterial Endocarditis." In Handbook of Animal Models of Infection. Elsevier, 1999. http://dx.doi.org/10.1016/b978-012775390-4/50211-6.

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Tureen, J., and E. Tuomanen. "Rabbit Model of Bacterial Meningitis." In Handbook of Animal Models of Infection. Elsevier, 1999. http://dx.doi.org/10.1016/b978-012775390-4/50214-1.

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Motschmann, M., and W. Behrens-Baumann. "Rabbit Model of Candida Keratomycosis." In Handbook of Animal Models of Infection. Elsevier, 1999. http://dx.doi.org/10.1016/b978-012775390-4/50224-4.

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Conference papers on the topic "Rabbit animal model"

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Czerchaujski, L., V. Hornsey, C. Prowse, and H. Bessos. "CROSS-REACTIV7E Fl/III :C IN THE RABBIT: A POTENTIAL ANIMAL MODEL FOR FUIII:C STUDIES." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644036.

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A one step Enzyme-linked immunosorbent assay (ELISA) incorporating two anti-human FVIII :Ag monoclonal antibodies (MAbs) was used to determine FUIIIrAg in rabbits. Initial examinations showed the presence of cross-reactive FUIII:C in rabbit serum, plasma, and homogenates of normal rabbit liver, lung and spleen. Detailed investigation of normal rabbit plasma, and plasma depleted with Sephacryl S1000-anti FVIII :C MAbs and irrelevant MAbs (as control) using the ELISA, a chromogenic Fl/III:C activity assay, an immunoradiometric assay (IRMA) using human antibody, and fast protein liquid chromatogr

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Zeng, Zijing, David F. Kallmes, Yong Hong Ding, et al. "Hemodynamics of Elastase-Induced Aneurysms in Rabbit: A New High Flow Bifurcation Model." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53819.

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An intracranial aneurysm (IA) is a pathological condition of cerebral arteries characterized by local enlargements of the arterial wall, typically into a saccular shape. Rupture of the aneurysm sac can result in devastating cerebral hemorrhage. Hemodynamic factors are believed to play an important role in initiation, development and rupture of IAs [1–3]. However, the coupling between hemodynamics and aneurysm pathophysiology is complex and remains poorly understood. Patient specific diagnostics regarding risk of rupture can be substantially advanced by improving our understanding of the in-viv

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Khraiche, Massoud L., Sharif El Emam, Abraham Akinin, Gert Cauwenberghs, William Freeman, and Gabriel A. Silva. "Visual evoked potential characterization of rabbit animal model for retinal prosthesis research." In 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2013. http://dx.doi.org/10.1109/embc.2013.6610306.

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Hotchkiss, A., C. Refino, L. DeGuzman, B. Rigter, and W. Eisert. "A NEW PAN SPECIES MODEL FOR THE MEASUREMENT OF IN VIVO THROMBOLYSIS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643176.

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A new model suitable for the quantitation of Li vivo thrombolytic efficacy was developed which has significant advantages over currently available models. This model allows animals to be used repeatedly and produces data that are less variable.This is a species-independent model utilizing an arterio-venous shunt (AVS). This model was used in rabbits (3 kg) and beagle dogs (13 kg). Each animal was used repeatedly during a 7 day experimental period without evidence of antibody formation. Clot lysis data are less variable than the rabbit jugular vein clot lysis model (RJV). The average coefficien

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DeLeo, Michael J., Matthew J. Gounis, Ajay K. Wakhloo, and Alexei A. Bogdanov. "Validation of Di-5-HT-Gd-DTPA, an Enzyme-Specific MR Contrast Agent for Myeloperoxidase, in the Rabbit Elastase Model of Cerebrovascular Aneurysm." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-206346.

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Characterization of molecular imaging probes in multiple animal models of disease is essential to increase their diagnostic potential. For example, we recently demonstrated visualization of active inflammation in a rabbit model saccular aneurysm using clinical field strength MRI and the paramagnetic MR contrast agent di-5-HT-GdDTPA, which has been shown in vitro to be sensitive and specific for the enzyme myeloperoxidase (MPO). While the use of transgenic mice (MPO−/−) has demonstrated specificity of di-5-HT-GdDTPA for MPO in a model of myocardial infarction [1], MPO-deficient rabbits are not

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Bauman, J. E., J. H. Joist, G. Vogler, and S. P. Sutera. "HIGH SUSCEPTIBILITY OF RABBIT, DOG, AND PIG PLATELETS TO SHEAR-INDUCED INJURY." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642846.

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In an attempt to develop an animal model for the study of the effects of fluid shear stress on platelet in vivo survival we examined the effects of repetitive short-duration (5 sec) and continuous prolonged (5 min) shear exposure in a cone-plate viscometer and Couette rotational viscometer on platelets (in citrated platelet-rich plasma) from humans, rabbits, dogs, and pigs. Comparable platelet aggregation (PAG = loss of single platelets) (18-64%) was observed with platelets from all species, associated with dense granule release, as a function of shear stress amplitude (25-50 dyn/cm2) under th

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Ditter, H., Fr R. Matthias, R. Voss, and P. Rottger. "PROSTACYCLIN IMPROVES SURVIVAL AND REDUCES MICROCLOT FORMATION IN RABBIT ENDOTOXEMIA." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644691.

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Arachidonic acid metabolites seem to play a pivotal role in the pathophysiology of endotoxin (ET) shock. Therefore, attempts to intervene into the balance of eicosanoids may affect the course of ET shock. Several studies had shown a reduction of ET-induced mortality by non-steroidal antiinflammatory drugs in various animal species.We investigated whether an infusion of prostacyclin (PGI2) has an effect on survival rates and on the incidence of renal microclots in a rabbit shock model, which is based on an intravenous infusion of ET over 4 hours. Thirty animals being exposed to 75 μg/kg x h of

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Cornelli, U., J. M. Welena, J. Fareed, X. Huan, and D. Hoppensteadt. "ANTITHROMBOTIC ACTIONS OF A SULFOMUCOPOLYSACCHARIDE MIXTURE (ATERIOD) IN ANIMAL MODELS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644160.

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Ateriod obtained from beef mucosal lining is a sulfomuco-polysaccharide mixture of various glycosaminoglycans which contains derma tans, heparatans and traces of heparin. It has been used in the treatment ofatherosclerosis and related vaso-oclusive disorders. Ateriod is standardized in terms of its lipoprotein lipase activation actions. Ateriod contains signfi-cant in vitro anticoagulant and antiprotease (anti-factor Xa and anti-factor Ila) activities as measured by clot-based and chromr ogenic substrate methods. However, this in vitro activity is 7-10 times lesser than heparin. In order to st

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O’Brien, Michael, Yifei Dai, and Glen L. Niebur. "Mechanical Validation of Computed Tomographic Quantification of Posterolateral Intertransverse Lumbar Fusion." In ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-192279.

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The New Zealand White (NZW) rabbit is often used as an animal model in posterolateral intrertransverse lumbar fusions [1]. Qualitative measures, such as manual palpation and radiographs, have been used to assess fusion mass [1]. However, an evaluation by sacrifice and biomechanical testing is the gold standard for quantitative data. A non-invasive approach to quantitatively assess the mechanics of spinal fusion could allow longitudinal studies with decreased need for animal sacrifice.

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Refino, C. J., B. Hultgren, S. Hollenbach, and A. Hotchkiss. "COMPARISON OF A BOLUS AND A INFUSION DOSE REGIMEN OF RECOMBINANT TISSUE TYPE PLASMINOGEN ACTIVATOR (rt-PA) ON THE RATE OF THROMBOLYSIS IN THE RABBIT JUGULAR VEIN MODEL (RJVM)." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643034.

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The success of intravenous infusion of rt-PA in the treatment of myocardial infarction, along with new applications in deep vein thrombosis and pulmonary embolism has stimulated interest in optimizing dosage regimens. Dosage strategies should be tested in a relevant animal model before clinical use. In the RJVM, net lysis is calculated frcm the difference in 1-125 fibrinogen present in a rabbit jugular vein thrombus, pre and post thrombolytic therapy, therefore changes in the rate of lysis would not be detected. To continuously monitor rates of lysis in the RJVM, a flat surface garrma detector

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