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Journal articles on the topic 'Radiation-induced complications'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Aggarwal, Himanshi, and Pradeep Kumar. "Radiation stents: Minimizing radiation-induced complications." South Asian Journal of Cancer 03, no. 03 (2014): 185. http://dx.doi.org/10.4103/2278-330x.136812.

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Peterson, Eric C., Kalpana M. Kanal, Renee L. Dickinson, Brent K. Stewart, and Louis J. Kim. "Radiation-Induced Complications in Endovascular Neurosurgery." Neurosurgery 72, no. 4 (2012): 566–72. http://dx.doi.org/10.1227/neu.0b013e318283c9a5.

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Abstract BACKGROUND: The incidence of radiation-induced complications is increasingly part of the informed consent process for patients undergoing neuroendovascular procedures. Data guiding these discussions in the era of modern radiation-minimizing equipment is lacking. OBJECTIVE: To quantify the rates of skin and hair effects at a modern high-volume neurovascular center, and to assess the feasibility of accurately quantifying the risk of future central nervous system (CNS) tumor formation. METHODS: We reviewed a prospectively collected database of endovascular procedures performed at our ins

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3

Mahid, S. S., M. Turina, C. Yashar, and S. Galandiuk. "Radiation-induced complications requiring surgical treatment." Journal of Clinical Oncology 23, no. 16_suppl (2005): 8266. http://dx.doi.org/10.1200/jco.2005.23.16_suppl.8266.

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Sycheva, I. V. "TREATMENT OF RADIATION-INDUCED PELVIC DAMAGE AFTER RADIATION THERAPY FOR PROSTATE CANCER." Siberian journal of oncology 17, no. 3 (2018): 64–71. http://dx.doi.org/10.21294/1814-4861-2018-17-3-64-71.

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Background. Radiation-induced damage to the pelvic organs (post-radiation proctitis, cystitis, urethritis) is a frequent complication after radiotherapy for prostate cancer. The reported frequency of late radiation damage to the pelvic organs is up to 30 %.Material and methods. The paper presents treatment outcomes of 149 with radiation-induced pelvic injuries caused by brachitherapy (15 patients) and combination treatment including brachitherapy and external beam radiation therapy (28 patients) for stage T1–3N0M0 prostate cancer. Radiationinduced rectitis (proctitis) was revealed in 149 patie

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Joubert, Kelley Sue. "The use of acupuncture in radiation-induced complications among cancer patients." Complementary Medicine: Education and Research 1, no. 1 (2023): 14–29. http://dx.doi.org/10.62415/vmij7249.

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Background: Radiation-induced complications commonly occur among patients who receive radiation therapy. Various research reports that acupuncture treatment significantly reduces radiation-induced complications experienced by patients undergoing radiation therapy. However, there is a lack of review on the use of acupuncture in the treatment of radiation-induced complications among cancer patients. Aim: The aim of this study was to conduct a narrative review on the use of acupuncture in the treatment of radiation-induced complications among cancer patients. Methodology: A narrative review was c

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Chattopadhyay, Jayanta, Subhalakshmi Sen, and Rakshith Shetty. "Current Concepts on the Pathogenesis and Management of Radiation-Induced Oral Mucositis: A Literature Review." International Journal of Health Sciences and Research 15, no. 4 (2025): 65–72. https://doi.org/10.52403/ijhsr.20250410.

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Radiation-induced mucositis (RIM) is a significant complication of cancer treatment, particularly for patients undergoing radiation therapy for head and neck cancers. Radiation-induced oral mucositis (RIOM) causes severe pain, difficulty in swallowing, and may lead to dose reduction or treatment delays, adversely impacting patient outcomes. This review compiles current literature on the pathophysiology, prevention, and management of RIOM, with a focus on pharmacologic, non-pharmacologic, and emerging therapeutic interventions. Understanding these concepts is essential for advancing care strate

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Gretskikh, K. V., L. B. Zavaliy, O. L. Evdokimova, N. A. Shamalov, and S. S. Petrikov. "Early and late facial neuropathy after radiosurgery of vestibulocochlear schwannomas." Vestnik nevrologii, psihiatrii i nejrohirurgii (Bulletin of Neurology, Psychiatry and Neurosurgery), no. 7 (July 20, 2023): 525–35. http://dx.doi.org/10.33920/med-01-2307-05.

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Stereotactic radiosurgery (SRS) is the method of choice for the treatment of vestibular schwannomas, due to its high frequency of tumor growth control and low complication rate. According to the world scientific literature, one of the rare late radiation induced complications is facial nerve paralysis. It is extremely rare to find reports of cases of prosoparesis that occurred during the first week after performing SRS. The potential etiology, pathogenesis, and management of this type of complication still remain a subject for discussion. As potential risk factors for the development of radiat

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Letschert, J. G. J. "The prevention of radiation-induced small bowel complications." European Journal of Cancer 31, no. 7-8 (1995): 1361–65. http://dx.doi.org/10.1016/0959-8049(95)00179-m.

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9

Bockel, S., A. Vallard, A. Lévy, et al. "Pharmacological modulation of radiation-induced oral mucosal complications." Cancer/Radiothérapie 22, no. 5 (2018): 429–37. http://dx.doi.org/10.1016/j.canrad.2017.11.006.

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Karseladze, N. D., O. A. Tiganova, L. I. Ilyenko, N. V. Orlova, and S. Z. Danelyan. "Long-term effects of radiation therapy in outpatient practice." Medical alphabet, no. 13 (May 13, 2024): 34–41. http://dx.doi.org/10.33667/2078-5631-2024-13-34-41.

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Moscow multidisciplinary clinical center «Kommunarka», Moscow, Russia SUMMARY Radiation therapy is one of the main methods of treating malignant neoplasms. Along with high efficiency, radiation therapy leads to complications in the early and late period. General practitioners and therapists are insufficiently familiar with long-term radiation-induced complications. The article presents data on the pathogenesis, clinical manifestations, diagnosis and treatment of radiation lesions of the bone system, lungs, myocardium, gastrointestinal tract, genitourinary system, hematopoiesis system, as well

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Friedman, William A., Frank J. Bova, Sirisha Bollampally, and Patrick Bradshaw. "Analysis of Factors Predictive of Success or Complications in Arteriovenous Malformation Radiosurgery." Neurosurgery 52, no. 2 (2003): 296–308. http://dx.doi.org/10.1227/01.neu.0000043692.51385.91.

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Abstract OBJECTIVE This study was undertaken to determine which factors were statistically predictive of radiological and clinical outcomes in the radiosurgical treatment of arteriovenous malformations (AVMs). METHODS The computerized dosimetric and clinical data for 269 patients were reviewed. The AVM nidus was hand-contoured on successive enhanced computed tomographic slices through the nidus, to allow detailed determinations of nidus volume, target miss, normal brain tissue treated, dose conformality, and dose gradient. In addition, a number of patient and treatment factors, including Spetz

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Quintero-Martinez, Juan A., Sandra N. Cordova-Madera, and Hector R. Villarraga. "Radiation-Induced Heart Disease." Journal of Clinical Medicine 11, no. 1 (2021): 146. http://dx.doi.org/10.3390/jcm11010146.

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Cancer incidence and survivorship have had a rising tendency over the last two decades due to better treatment modalities. One of these is radiation therapy (RT), which is used in 20–55% of cancer patients, and its basic principle consists of inhibiting proliferation or inducing apoptosis of cancer cells. Classically, photon beam RT has been the mainstay therapy for these patients, but, in the last decade, proton beam has been introduced as a new option. This newer method focuses more on the tumor and affects less of the surrounding normal tissue, i.e., the heart. Radiation to the heart is a c

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Kordzińska-Cisek, Izabela, and Ludmiła Grzybowska-Szatkowska. "Complications of radio- and radiochemotherapy in patients undergoing major salivary gland cancer surgery." Otolaryngologia Polska 73, no. 3 (2019): 26–31. http://dx.doi.org/10.5604/01.3001.0013.0508.

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Purpose: The aim of this retrospective study was to present the prevalence of early and late radiation-induced reaction and factors affecting its formation and severity in patients after adjuvant radio- or radiochemotherapy in salivary gland cancer. Material and methods: A total of 113 patients with early and 91 with late radiation-induced reaction, irradiated in 2006-2016 were enrolled in the study. The frequency of acute mucosal radiation-induced reaction, time of onset, intensity, healing time, as well as the incidence of late radiation-induced reaction from the skin and subcutaneous tissue

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Muratov, R. M., S. I. Babenko, and M. N. Sorkomov. "Current view on radiation-induced heart disease and methods of its diagnosis." Russian Journal of Transplantology and Artificial Organs 24, no. 4 (2022): 39–45. http://dx.doi.org/10.15825/1995-1191-2022-4-39-45.

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In recent years, cardiologists and cardiovascular surgeons are increasingly encountering radiation-induced heart disease (RIHD) in their practice. This complication is described in literature but is poorly understood and clinically challenging. Radiation therapy (RT) is widely used in the treatment of many cancers. Despite the considerable risk of RT complications, it is used in 20–55% of cancer patients. Radiation-associated cardiotoxicity appears to be delayed, typically 10 to 30 years following treatment. Mediastinal irradiation significantly increases the risk of non-ischemic cardiomyopath

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Meidarlina, Ista, and Adji Kusumadjati. "Head and Neck Cancer Patient’s Radiation-induced Oral and Temporomandibular Joint Complications: A Review." Journal of International Oral Health 16, no. 6 (2024): 432–38. https://doi.org/10.4103/jioh.jioh_46_24.

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Abstract Aims: This study describes complications that transpired inside the mouth and the temporomandibular joint (TMJ) after radiotherapy treatment in individuals with cancer of the head and neck. Materials and Methods: The PubMed database of the United States National Library of Medicine and ProQuest were used as electronic databases of articles published from 2012 to 2022 by using keywords “radiotherapy-induced oral complication,” “radiotherapy induced temporomandibular joint disorders,” and “complication post-radiotherapy for head and neck cancer (HNC) patient.” Articles were filtered aft

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G, Rupam, Balaji O, Sereen Rt, and Navin Patil. "RADIATION THERAPY-INDUCED SUBACUTE INTESTINAL OBSTRUCTION." Asian Journal of Pharmaceutical and Clinical Research 10, no. 7 (2017): 7. http://dx.doi.org/10.22159/ajpcr.2017.v10i7.18520.

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Radiation therapy is an important treatment modality for malignancies of the cervix, uterus, prostate, bladder, testes, and rectum. The incidence of clinically significant radiation-related complications is about 5-20%. Radiation insult to gastrointestinal tract includes damage to the small bowel, colon, and rectum. Predisposing risk factors such as previous surgery, hypertension, diabetes, smoking, hyperbaric oxygen increases the severity of damage as well as the use of other chemotherapeutic agents increases the sensitivity to radiation. Radiation-induced injury can be acute or chronic depen

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Kozhukhov, S., O. Bazyka, N. Dovganych, O. Yarynkina, and N. Tkhor. "RADIOTHERAPY-ASSOCIATED CARDIOVASCULAR COMPLICATIONS IN CANCER (review)." Проблеми радіаційної медицини та радіобіології = Problems of Radiation Medicine and Radiobiology 25 (2020): 56–74. http://dx.doi.org/10.33145/2304-8336-2020-25-56-74.

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The review is devoted to the current issues of radiation-induced cardiovascular complications, their diagnostics and incidence depending on the radiation doses and exposure regimens, potential efficiency of the screening strategies for cardiotoxicity monitoring after radiotherapy in cancer patients by analyzing the data from literature and clinical trials, based on recommendations of European Society of Cardiology and European Society of Medical Oncology. Key words: cardiovascular complications, radiation therapy.

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Karlsson, Bengt, Lars Kihlström, Christer Lindquist, Kaj Ericson, and Ladislau Steiner. "Radiosurgery for cavernous malformations." Journal of Neurosurgery 88, no. 2 (1998): 293–97. http://dx.doi.org/10.3171/jns.1998.88.2.0293.

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Object. The authors examined 22 patients with cavernous malformations (CMs) who had undergone gamma knife radiosurgery (GKRS) to assess the value of this procedure in treating these lesions. Methods. At the Karolinska Hospital, GKRS was used to treat 23 patients with CMs during the period of 1985 through 1996. One of the patients was lost to follow up and the treatment results of the 22 remaining patients were analyzed. In the first half of the series, the CMs were treated with high doses of radiation (> 15-Gy dose to the periphery); in the second half of the series, lower doses were used.

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Skitioui, Ihsane, Rachida Laraichi, Salma Ichou, et al. "RADIATION INDUCED SUBACUTE SPONTANEOUS BLADDER RUPTURE IN CERVICAL CANCER PATIENT: A CASE REPORT AND REVIEW OF THE LITERATURE." International Journal of Advanced Research 13, no. 01 (2025): 1023–34. https://doi.org/10.21474/ijar01/20289.

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Cervical cancer is the fourth most common cancer among women worldwide, with locally advanced cases often necessitating multimodal treatment, in which radiation therapy remains the mainstay. Although effective, radiation therapy can lead to severe, albeit rare, complications such as spontaneous bladder rupture (SBR). This report presents a case of a 47-year-old woman with FIGO Stage IVa cervical adenocarcinoma who developed SBR following external beam radiation therapy (EBRT) without the inclusion of brachytherapy due to the tumors size. Initially managed with conservative treatment, her condi

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O[apos ]Donnell, Thomas F., Gordon R. Phillips, Richard M. Peer, and James F. Upson. "Late complications of revascularization for radiation-induced arterial disease." Journal of Vascular Surgery 16, no. 6 (1992): 0921–25. http://dx.doi.org/10.1067/mva.1992.41751.

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Phillips, Gordon R., Richard M. Peer, James F. Upson, and John J. Ricotta. "Late complications of revascularization for radiation-induced arterial disease." Journal of Vascular Surgery 16, no. 6 (1992): 921–25. http://dx.doi.org/10.1016/0741-5214(92)90055-d.

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22

Blesl, Andreas, Iva Brcic, Werner Jaschke, Dietmar Öfner, Peter Fickert, and Johannes Plank. "Chronic gastric ulcer disease complicating selective internal radiation therapy (SIRT) in a patient with cholangiocellular carcinoma." Zeitschrift für Gastroenterologie 57, no. 11 (2019): 1304–8. http://dx.doi.org/10.1055/a-1016-3698.

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AbstractSelective internal radiation therapy (SIRT) is a therapeutic option for primary and metastatic liver tumors. Microspheres containing Yttrium 90, a beta-emitting radionuclide, are administered into the hepatic artery allowing selective internal radiation of a liver tumor. SIRT-related complications may appear due to migration of the radiation microspheres to organs distant from the tumor site. In order to prevent these complications, unintended non target embolization of Yttrium microspheres has to be avoided. However, data from external-beam radiation therapy (EBRT) suggests that the s

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Süslü, Hikmet Turan, and Mustafa Bozbuga. "Frontal Meningioma After Postoperative Cranial Irradiation for Posterior Fossa Medulloblastoma." Sinir Sistemi Cerrahisi Dergisi 2, no. 4 (2009): 183–87. https://doi.org/10.54306/sscd.2009.51.

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The development of cranial neoplasms subsequent to therapeutic radiation therapy (RT) is a rare entity but a serious complication. Radiation induced meningiomas are late complications in patients who have received high dose irradiation for brain tumors and the most common form of radiation-induced neoplasm. Radiation- induced meningiomas occuring after treatment of a medulloblastoma are rarely seen. We present a case of a 21-year-old male with frontal meningioma developed after 13 years from neuroaxis radiation therapy for medulloblastoma. Surgical resection and RT was applied for our patient

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Nishio, S., T. Morioka, T. Inamura, et al. "Radiation-Induced Brain Tumours: Potential Late Complications of Radiation Therapy for Brain Tumours." Acta Neurochirurgica 140, no. 8 (1998): 763–70. http://dx.doi.org/10.1007/s007010050177.

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Kumar, Dheeraj, and Namrata Rastogi. "Oral Complications and Its Management during Radiotherapy." International Journal of Head and Neck Surgery 2, no. 2 (2011): 109–13. http://dx.doi.org/10.5005/jp-journals-10001-1062.

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ABSTRACT Cancer is a class of diseases in which a cell or a group of cells display uncontrolled growth, invasion, and sometimes metastasis. The term head and neck cancer refers to a group of biologically similar cancers originating from the upper aerodigestive tract, including the lip, oral cavity, nasal cavity, paranasal sinuses, pharynx and larynx. About 90% of head and neck cancers are squamous cell carcinomas, originating from the mucosal lining (epithelium) of these regions. Radiation therapy is the most common form of treatment along with surgery and chemotherapy. There are different for

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Loginova, I. Yu, O. V. Kamenskaya, S. O. Danilenko, et al. "Radiation-induced lung injury in malignant thoracic neoplasms: current state of the problem, trends in prevention and rehabilitation." PULMONOLOGIYA 34, no. 4 (2024): 471–77. http://dx.doi.org/10.18093/0869-0189-2024-34-4-471-477.

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Radiation-induced lung injury is one of the most serious complications of radiation therapy in patients with malignant thoracic neoplasms. It results from accumulation of radiation dose in the lung tissue and can lead to development of various pathological changes in the lungs, such as fibrosis, pneumonitis and pulmonary hypertension. Post-radiation lung injury can significantly reduce the patient’s quality of life and worsen the prognosis. Aim. This literature review analyzes the causes of radiation-induced lung injury, describes the main clinical manifestations and diagnostic methods, and al

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Gibbs, Iris C., Chirag Patil, Peter C. Gerszten, John R. Adler, and Steven A. Burton. "DELAYED RADIATION-INDUCED MYELOPATHY AFTER SPINAL RADIOSURGERY." Neurosurgery 64, suppl_2 (2009): A67—A72. http://dx.doi.org/10.1227/01.neu.0000341628.98141.b6.

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Abstract OBJECTIVE Spinal cord injury is arguably the most feared complication in radiotherapy and has historically limited the aggressiveness of spinal tumor treatment. We report a case series of 6 patients treated with radiosurgery who developed delayed myelopathy. METHODS Between 1996 and 2005, 1075 patients with benign or malignant spinal tumors were treated by CyberKnife (Accuray, Inc., Sunnyvale, CA) robotic radiosurgery at Stanford University Medical Center and the University of Pittsburgh Medical Center. Patients were followed prospectively with clinical and radiographic assessments at

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Paul, Manu, Bhavya Kumar, Deepa Philip, and Bhaskar Sugath. "Radiation induced osteosarcoma of clavicle: A case report." Journal of Medical and Allied Sciences 14, no. 1 (2023): 61. http://dx.doi.org/10.5455/jmas.88064.

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Radiation induced sarcomas (RIS) are the most dreaded long-term complications of head and neck irradiation. RISs are usually high grade and aggressive in nature. Although osteosarcoma is a common RIS in head and neck region, radiation induced osteosarcoma of the clavicle is rarely reported and generalized outcome is poor. Here we report a case of radiation induced osteosarcoma of the clavicle following neck irradiation for a carcinoma of tongue.

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Pereira, Luiz Claudio Modesto, Valeria Patricia De Araujo, and Thiago Henrique de Moraes Modesto. "The Downside of Radiosurgery, Possible Complications." JBNC - JORNAL BRASILEIRO DE NEUROCIRURGIA 25, no. 3 (2018): 286–99. http://dx.doi.org/10.22290/jbnc.v25i3.1141.

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As a consequence of various last century scientific and technological advances radiotherapy and stereotactic radiosurgery (SRS) have emerged as safe and efficacious techniques for the treatment of various intracranial pathologies. Recent improvements such as in brain and tumor imaging, patient immobilization, 3D planning and radiation delivery allow it to target lesions more accurately and minimize radiation delivered to normal brain, leading to drastic improvements in terms of safety and post-therapy complication. Despite that SRS still implies in moderate to severe side effects in one fifth

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Odlum, O. "Preventive Resins in the Management of Radiation-Induced Xerostomia Complications." Journal of Esthetic and Restorative Dentistry 3, no. 6 (1991): 227–29. http://dx.doi.org/10.1111/j.1708-8240.1991.tb00820.x.

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Isaev, I. G., F. A. Guliev, K. S. Akperov, and N. R. Alieva. "Analysis of the frequency of radiation therapy complications in patients with prostate cancer." Kazan medical journal 98, no. 5 (2017): 680–86. http://dx.doi.org/10.17750/kmj2017-680.

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Aim. Study of the frequency of radiation therapy complications in patients with prostate cancer.  Methods. The study included 142 patients who underwent radiation therapy combined with hormonal therapy in 2001-2015. Average age of patients was 68 years. All of them received 3D-conformal radiotherapy by linear accelerators with 6 to 15 MV photon beams. Single boost dose was 2 Gy, total boost dose was 75 Gy. We studied frequency and severity of acute hematological toxicity and early and late gastroenterological and urological complications of the treatment. Treatment-related toxicity was a

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Korytov, Oleg, Luiza Korytova, Artur Akhtemzyanov, Valentina Sokurenko, Mikhail Shkolnik, and Yelizaveta Maslyukova. "EXPERIMENTAL MODELS OF RADIATION-INDUCED CYSTITIS IN LABORATORY ANIMALS (LITERATURE REVIEW)." Problems in oncology 65, no. 3 (2019): 337–41. http://dx.doi.org/10.37469/0507-3758-2019-65-3-337-341.

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Over the past 20 years, there has been a trend towards an increase in cancer morbidity in most states, in particular in the US and Russia, for a number of localizations, for example, prostate cancer, uterus, rectum and bladder cancer [6]. These localizations require radiation therapy at least as a part of multi-modal approach, or, quite often, as an independent method of treatment. However, frequency of acute radiation cystitis, according to current publications, after irradiation of the pelvis, remains high 5 to 80% for 100 days)/ Frequency of late radiation complications, which can occur fro

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Topuzov, E. E., T. T. Agishev, K. A. Fedorov, et al. "Transcutaneous oxegen measurement in the area of soft tissue radiation-induced fibrosis in patients with breast cancer." HERALD of North-Western State Medical University named after I.I. Mechnikov 10, no. 2 (2018): 58–63. http://dx.doi.org/10.17816/mechnikov201810258-63.

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Late radiation injury in the form of radiation-induced fibrosis is one of the many complications of radiation therapy.In current literature, pathogenesis of radiation-induced fibrosis is considered from several angles. According to one of the hypotheses, the main cause of pathogenesis of radiation-induced fibrosis is damage of the blood vessels caused by radiation. Another hypothesis insists that radiation causes depletion of specific cell populations in the irradiated area, reducing the number of stem cells (mostly, fibroblasts). (For citation: Topuzov EE, Agishev TT, Fedorov КА, et al. Trans

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Baranyai, Zsolt, Dániel Sinkó, Valéria Jósa, Attila Zaránd, and Dániel Teknős. "Therapy of radiation enteritis – current challenges." Orvosi Hetilap 152, no. 28 (2011): 1120–24. http://dx.doi.org/10.1556/oh.2011.29141.

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Radiation enteritis is one of the most feared complications after abdominal and pelvic radiation therapy. The incidence varies from 0.5 to 5%. It is not rare that the slowly progressing condition will be fatal. During a period of 13 years 24 patients were operated due to the complication of radiation enteritis. Despite different types of surgery repeated operation was required in 25% of cases and finally 4 patients died. Analyzing these cases predisposing factors and different therapeutic options of this condition are discussed. Treatment options of radiation induced enteritis are limited; how

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Zanoni, Cortesi, Zamagni, and Tesei. "The Role of Mesenchymal Stem Cells in Radiation-Induced Lung Fibrosis." International Journal of Molecular Sciences 20, no. 16 (2019): 3876. http://dx.doi.org/10.3390/ijms20163876.

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Radiation therapy is one of the most important treatment modalities for thoracic tumors. Despite significant advances in radiation techniques, radiation-induced lung injury (RILI) still occurs in up to 30% of patients undergoing thoracic radiotherapy, and therefore remains the main dose-limiting obstacle. RILI is a potentially lethal clinical complication of radiotherapy that has 2 main stages: an acute stage defined as radiation pneumonitis, and a late stage defined as radiation-induced lung fibrosis. Patients who develop lung fibrosis have a reduced quality of life with progressive and irrev

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Kilic, Diclehan, Seren Ozenirler, Ibrahim Egehan, and Ayse Dursun. "Sulfasalazine Decreases Acute Gastrointestinal Complications Due to Pelvic Radiotherapy." Annals of Pharmacotherapy 35, no. 7-8 (2001): 806–10. http://dx.doi.org/10.1345/aph.10055.

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BACKGROUND: Radiation-induced gastrointestinal toxicity is a significant concern for patients who are treated with this modality for pelvic malignancies. Eicosanoids and free radicals are thought to be among the reasons for this effect. Sulfasalazine is an inhibitor of their synthesis in the mucosa. OBJECTIVE: To determine whether sulfasalazine can reduce the radiation-induced acute gastrointestinal complications. METHODS: In this prospective, double-blind study, 31 patients receiving pelvic radiotherapy were randomized to receive two sulfasalazine 500-mg tablets twice daily or placebo, admini

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Hoeltgen, Line, Eva Meixner, Philipp Hoegen-Saßmannshausen, et al. "Helium Ion Therapy for Advanced Juvenile Nasopharyngeal Angiofibroma." Cancers 16, no. 11 (2024): 1993. http://dx.doi.org/10.3390/cancers16111993.

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Helium ion therapy (HRT) is a promising modality for the treatment of pediatric tumors and those located close to critical structures due to the favorable biophysical properties of helium ions. This in silico study aimed to explore the potential benefits of HRT in advanced juvenile nasopharyngeal angiofibroma (JNA) compared to proton therapy (PRT). We assessed 11 consecutive patients previously treated with PRT for JNA in a definitive or postoperative setting with a relative biological effectiveness (RBE) weighted dose of 45 Gy (RBE) in 25 fractions at the Heidelberg Ion-Beam Therapy Center. H

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Korymasov, E. A., M. A. Medvedchikov-Ardiia, and A. S. Benian. "A clinical case of stepwise correction of the chest wall complications after combined treatment for breast cancer." Almanac of Clinical Medicine 47, no. 8 (2020): 740–44. http://dx.doi.org/10.18786/6/2072-0505-2019-47-076.

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Radiation-induced sternal osteomyelitis as a complication of combined therapy for breast cancer is quite rare. As a rule, these patients are treated not by oncologists, but by thoracic and general surgeons. We present a clinical case report of successful treatment of chronic radiation-induced sternal osteomyelitis in a 52-yearold woman, who developed it at 2 years after radical mastectomy for breast cancer. The patient recovered after long-term, stepwise treatment including surgical procedures. The infectious process was stopped by wound debridement and vacuum-assisted dressings. The reconstru

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Wood, J., J. Ver Halen, S. Samant, and N. Florendo. "Radiation-induced sarcoma masquerading as osteoradionecrosis: case report and literature review." Journal of Laryngology & Otology 129, no. 3 (2015): 279–82. http://dx.doi.org/10.1017/s0022215114003326.

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AbstractBackground:Radiation therapy is a commonly used treatment in head and neck oncology, whether used alone or as an adjunct to other treatments. Osteoradionecrosis and radiation-induced malignancy are both rare, late complications of radiation therapy.Methods:This paper describes a case of radiation-induced sarcoma of the mandible initially presenting as osteoradionecrosis. In addition, the literature on the identification and treatment of these entities is reviewed.Results:The patient underwent excision and reconstruction of the presumed osteoradionecrosis. Final pathology demonstrated r

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Yi, Ann, Hak Hee Kim, Hee Jung Shin, Mi Ock Huh, Seung Do Ahn, and Bo Kyeong Seo. "Radiation-Induced Complications after Breast Cancer Radiation Therapy: a Pictorial Review of Multimodality Imaging Findings." Korean Journal of Radiology 10, no. 5 (2009): 496. http://dx.doi.org/10.3348/kjr.2009.10.5.496.

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Lan, Fujun, Jean Jeudy, Suresh Senan, et al. "Should regional ventilation function be considered during radiation treatment planning to prevent radiation-induced complications?" Medical Physics 43, no. 9 (2016): 5072–79. http://dx.doi.org/10.1118/1.4960367.

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Eldweik, Luai. "Radiation induced tissue necrosis mimicking orbital apex syndrome." SAGE Open Medical Case Reports 10 (January 2022): 2050313X2211232. http://dx.doi.org/10.1177/2050313x221123292.

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We are reporting a unique case with findings resembling orbital apex syndrome due to radiation-induced ischemic tissue necrosis following the treatment of meningiomatosis. In our patient, radiation injury caused multiple neuropathies including: 2nd, 3rd, 4th, 5th, and 6th neuropathies with oculosympathetic pathway involvement. To our knowledge, our patient has some unique features of complications related to radiation necrosis. Describing this case will help clinicians to have a better understanding of the extent of ocular manifestations secondary to radiation necrosis.

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Sterling, Joshua, Syed N. Rahman, Ajin Varghese, Javier C. Angulo, and Dmitriy Nikolavsky. "Complications after Prostate Cancer Treatment: Pathophysiology and Repair of Post-Radiation Urethral Stricture Disease." Journal of Clinical Medicine 12, no. 12 (2023): 3950. http://dx.doi.org/10.3390/jcm12123950.

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Radiation therapy (RT) in the management of pelvic cancers remains a clinical challenge to urologists given the sequelae of urethral stricture disease secondary to fibrosis and vascular insults. The objective of this review is to understand the physiology of radiation-induced stricture disease and to educate urologists in clinical practice regarding future prospective options clinicians have to deal with this condition. The management of post-radiation urethral stricture consists of conservative, endoscopic, and primary reconstructive options. Endoscopic approaches remain an option, but with l

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D’Andrea, Marco, Marcello Benassi, and Lidia Strigari. "Modeling Radiotherapy Induced Normal Tissue Complications: An Overview beyond Phenomenological Models." Computational and Mathematical Methods in Medicine 2016 (2016): 1–9. http://dx.doi.org/10.1155/2016/2796186.

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An overview of radiotherapy (RT) induced normal tissue complication probability (NTCP) models is presented. NTCP models based on empirical and mechanistic approaches that describe a specific radiation induced late effect proposed over time for conventional RT are reviewed with particular emphasis on their basic assumptions and related mathematical translation and their weak and strong points.

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Tuan, Hoang, Vu Vinh, Tran Anh, Tong Hai, Tran Phu, and Trinh Dung. "Flap Application in Reconstructive Surgery to Manage Severe Radiation-induced Ulcers: A Case Series." Wounds: a compendium of clinical research and practice 35, no. 1 (2023): e7-e13. http://dx.doi.org/10.25270/wnds/21090.

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Introduction. Radiation-induced ulceration is a late-stage skin reaction after RT for cancer treatment. Objective. The present study examined the use of a single-stage reconstructive procedure to manage radiation-related wounds. Materials and Methods. Nine patients with radiation-induced chronic ulcer with accompanying severe complications were admitted to the Plastic, Reconstructive, and Regenerative Center of Viet Nam National Burn Hospital between October 2015 and September 2019. The patients ranged in age from 49 to 77 years. Complications included exposed cheekbone (n = 1), exposed trache

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Ghezzi, Fabio, Antonella Cromi, Maurizio Serati, et al. "Radiation-Induced Bowel Complications: Laparoscopic Versus Open Staging of Gynecologic Malignancy." Annals of Surgical Oncology 18, no. 3 (2010): 782–91. http://dx.doi.org/10.1245/s10434-010-1382-8.

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Erickson, B. A., K. J. Murray, S. J. Erickson, and G. F. Carrera. "Radiation-induced pelvic bone complications: An underestimated sequelae of pelvic irradiation." International Journal of Radiation Oncology*Biology*Physics 48, no. 3 (2000): 126. http://dx.doi.org/10.1016/s0360-3016(00)80048-6.

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Pikarsky, A. J., J. Efron, E. G. Weiss, J. J. Nogueras, S. D. Wexner, and B. Belin. "Complications following formalin installation in the treatment of radiation induced proctitis." International Journal of Colorectal Disease 15, no. 2 (2000): 96–99. http://dx.doi.org/10.1007/s003840050240.

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LEONTIEV, ALEXANDER V., ELENA A. GRISHINA, MIKHAIL A. DANILOV, NIKOLAY S. KARNAUKHOV, and KIRILL V. SHISHIN. "USING AUTOLOGOUS MICROFRAGMENTED ADIPOSE TISSUE IN THE TREATMENT OF RADIATION-INDUCED ULCERATIVE PROCTITIS." Bulletin of Contemporary Clinical Medicine 16, suppl.2 (2023): 91–96. http://dx.doi.org/10.20969/vskm.2023.16(suppl.2).91-96.

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Abstract. Introduction. Radiation-induced ulcerative proctitis is a serious complication of cancer radiotherapy for prostate, cervix, uterine body, anal canal, and other pelvic tumors. Given the development pattern, there are currently no pathogenetic methods for the treatment of radiation-induced ulcerative proctitis. Aim: To develop a technique for and evaluate its eﬀectiveness in the treatment of patients with radiation-induced rectal ulcers using autologous microfragmented adipose tissue. Materials and Methods. The study included 30 patients, of which 24 (80.0%) were women and 6 (20.0%) we

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Midena, Giulia, Raffaele Parrozzani, Luisa Frizziero, and Edoardo Midena. "Chorioretinal Side Effects of Therapeutic Ocular Irradiation: A Multimodal Imaging Approach." Journal of Clinical Medicine 9, no. 11 (2020): 3496. http://dx.doi.org/10.3390/jcm9113496.

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Radiation chorioretinopathy, radiation maculopathy, and radiation optic neuropathy are the major complications of ophthalmic radiotherapy. Optical coherence tomography (OCT) and OCT angiography (OCTA) are revolutionary imaging methods, allowing the visualization of the retinal cellular architecture and the retinal vascular system, respectively. In recent years this multimodal imaging approach has been applied to several retinal disease, but its role in the clinical characterization of retinal complications secondary to ophthalmic radiotherapy has not yet been defined. The purpose of this revie

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