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1

Simopoulos, Thomas T. "Response to Pulsed and Continuous Radiofrequency Lesioning of the Dorsal Root Ganglion and Segmental Nerves in Patients with Chronic Lumbar Radicular Pain." Pain Physician 2;11, no. 3;2 (March 14, 2008): 137–44. http://dx.doi.org/10.36076/ppj.2008/11/137.

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Objectives: We aimed to prospectively evaluate the response and safety of pulsed and continuous radiofrequecy lesioning of the dorsal root ganglion/segmental nerves in patients with chronic lumbosacral radicular pain. Methods: Seventy-six patients with chronic lumbosacral radicular pain refractory to conventional therapy met the inclusion criteria and were randomly assigned to one of 2 types of treatment, pulsed radiofrequency lesioning of the dorsal root ganglion/segmental nerve or pulsed radiofrequency followed immediately by continuous radiofrequency. Patients were carefully evaluated for neurologic deficits and side effects. The response was evaluated at 2 months and was then tracked monthly. A Kaplan-Meier analysis was used to illustrate the probability of success over time and a Box-Whisker analysis was applied to determine the mean duration of a successful analgesic effect. Results: Two months after undergoing radiofrequency treatment, 70% of the patients treated with pulsed radiofrequency and 82% treated with pulsed and continuous radiofrequency had a successful reduction in pain intensity. The average duration of successful analgesic response was 3.18 months (± 2.81) in the group treated with pulsed radiofrequency and 4.39 months (±3.50) in those patients treated with pulsed and continuous radiofrequency lesioning. A Kaplan-Meier analysis illustrated that in both treatment groups the chance of success approached 50% in each group at 3 months. The vast majority of patients had lost any beneficial effects by 8 months. There was no statistical difference between the 2 treatment groups. No side effects or neurological deficits were found in either group. Conclusion: Pulsed mode radiofrequency of the dorsal root ganglion of segmental nerves appears to be a safe treatment for chronic lumbosacral radicular pain. A significant number of patients can derive at least a short-term benefit. The addition of heat via continuous radiofrequency does not offer a significant advantage. A randomized controlled trial is now required to determine the effectiveness of pulsed radiofrequency. Key words: Pulsed radiofrequency lesioning, dorsal root ganglion, segmental nerve, continuous radiofrequency lesioning, chronic lumbosacral radicular pain
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Chang, Stephen KY, Wah Wah Hlaing, Liangjing Yang, and Chee Kong Chui. "Current Technology in Navigation and Robotics for Liver Tumours Ablation." Annals of the Academy of Medicine, Singapore 40, no. 5 (May 15, 2011): 231–36. http://dx.doi.org/10.47102/annals-acadmedsg.v40n5p231.

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Radiofrequecy ablation is the most widely used local ablative therapy for both primary and metastatic liver tumours. However, it has limited application in the treatment of large tumours (tumours >3cm) and multicentric tumours. In recent years, many strategies have been developed to extend the application of radiofrequency ablation to large tumours. A promising approach is to take advantage of the rapid advancement in imaging and robotic technologies to construct an integrated surgical navigation and medical robotic system. This paper presents a review of existing surgical navigation methods and medical robots. We also introduce our current developed model — Transcutaneous Robot-assisted Ablation-device Insertion Navigation System (TRAINS). The clinical viability of this prototyped integrated navigation and robotic system for large and multicentric umors is demonstrated using animal experiments. Keywords: Computer aided surgery, Liver, Radiofrequency ablation
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Huang, Yuelong, Yujun Zhang, Xiaoquan Ding, Songyang Liu, and Tiezheng Sun. "Working conditions of bipolar radiofrequency on human articular cartilage repair following thermal injury during arthroscopy." Chinese Medical Journal 127, no. 22 (November 20, 2014): 3881–86. http://dx.doi.org/10.3760/cma.j.issn.0366-6999.20141833.

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Background The thermal injury during bipolar radiofrequercy results in chondrocyte death that limits cartilage repair. The purpose was to determine the effects of various factors of bipolar radiofrequency on human articular cartilage after thermal injury, offering suitable working conditions for bipolar radiofrequency during arthroscopy. Methods Osteochondral explants from 28 patients undergoing total knee arthroplasty (TKA) in Department of Orthopaedic, Peking University Reople's Hospital from October 2013 to May 2014, were harvested and treated using bipolar radiofrequency in a light contact mode under the following conditions: various power setting of levels 2, 4 and 6; different durations of 2 seconds, 5 seconds and 10 seconds; irrigation with fluids of different temperatures of 4°C, 22°C, and 37°C; two different bipolar radiofrequency probes ArthroCare TriStar 50 and Paragon T2. The percentage of cell death and depth of cell death were quantified with laser confocal microscopy. The content of proteoglycan elution at different temperatures was determined by spectrophotometer at 530 nm. Results Chondrocyte mortality during the treatment time of 2 seconds and power setting of level 2 was significantly lower than that with long duration or in higher level groups (time: P=0.001; power: P=0.001). The percentage of cell death after thermal injury was gradually reduced by increasing the temperature of the irrigation solutions (P=0.003), the depth of dead chondrocytes in the 37°C solution group was significantly less than those in the 4°C and 22°C groups (P=0.001). The proteoglycan elution was also gradually reduced by increasing the temperature (P=0.004). Compared with the ArthroCare TriStar 50 group, the percentage of cell death in the Paragon T2 group was significantly decreased (P=0.046). Conclusions Thermal chondroplasty with bipolar radiofrequency resulted in defined margins of chondrocyte death under controlled conditions. The least cartilage damage during thermal chondroplasty could be achieved with lower power, shorter duration, suitable temperature of irrigation solutions and chondroprotective probes. The recommendations for the use of bipolar radiofrequency to minimize cartilage damage could be achieved with a power setting of level 2, treatment duration of 2 seconds, suitable fluid temperature (closer to body temperature of 37°C) and chondroprotective Paragon T2 probes.
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Shah, Neha. "Applications of Radiofrequency in Ent." Journal of Clinical Otorhinolaryngology 2, no. 1 (June 19, 2020): 01–02. http://dx.doi.org/10.31579/2692-9562/003.

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Radiofrequency proves to be a useful tool for snoring and obstructive sleep apnoea cases. Its advantages include relative precision in incision making, relatively bloodless fields if used appropriately, decrease postoperative pain and excellent healing with fibrosis which aids in stiffening tissues. Radiofrequency is high frequency alternating current used to ablate (cut/coagulate) tissues. Radiofrequency ablation treatment can be applied to nasal turbinates, soft palate, tongue base, tonsils etc and it can be used in various surgeries in the cutting mode to improve obstructive sleep disordered breathing.
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Sabanovic, Jusuf, Samir Muhovic, Ajdin Rovcanin, Safet Musanovic, Salem Bajramagic, and Edin Kulovic. "Radiofrequency Assisted Hepatic Parenchyma Resection Using Radiofrequent Generator (RF) Generator." Acta Informatica Medica 26, no. 4 (2018): 265. http://dx.doi.org/10.5455/aim.2018.26.265-268.

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6

Scholtz, Leonie. "Radiofrequency ablation." South African Journal of Radiology 8, no. 1 (June 5, 2004): 2. http://dx.doi.org/10.4102/sajr.v8i1.134.

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Cha, Young Deog. "Pulsed Radiofrequency." Korean Journal of Pain 17, Suppl (2004): S74. http://dx.doi.org/10.3344/kjp.2004.17.s.s74.

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SHIINA, Shuichiro, Takuma TERATANI, Hideo YOSHIDA, Masatoshi AKAMATSU, Mikio YANASE, and Masao OMATA. "Radiofrequency Ablation." JOURNAL OF JAPAN SOCIETY FOR CLINICAL ANESTHESIA 26, no. 3 (2006): 281–88. http://dx.doi.org/10.2199/jjsca.26.281.

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9

Tan, Marcus G., Shilpi Khetarpal, and Jeffrey S. Dover. "Radiofrequency Microneedling." Advances in Cosmetic Surgery 5, no. 1 (May 2022): 17–25. http://dx.doi.org/10.1016/j.yacs.2021.12.005.

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Racz, G. B., and R. Ruiz-Lopez. "Radiofrequency Procedures." Pain Practice 6, no. 1 (March 2006): 46–50. http://dx.doi.org/10.1111/j.1533-2500.2006.00058.x.

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11

Shea, Martha C. "Radiofrequency ablation." Nursing 34, no. 12 (December 2004): 32hn1–32hn4. http://dx.doi.org/10.1097/00152193-200412000-00029.

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Van Boxem, Koen, Marc Huntoon, Jan Van Zundert, Jacob Patijn, Maarten van Kleef, and Elbert A. Joosten. "Pulsed Radiofrequency." Regional Anesthesia and Pain Medicine 39, no. 2 (2014): 149–59. http://dx.doi.org/10.1097/aap.0000000000000063.

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Cohen, Steven P., and Jan Van Zundert. "Pulsed Radiofrequency." Regional Anesthesia and Pain Medicine 35, no. 1 (January 2010): 8–10. http://dx.doi.org/10.1097/aap.0b013e3181c7705f.

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14

Sluijter, Menno E. "Pulsed Radiofrequency." Anesthesiology 103, no. 6 (December 1, 2005): 1313. http://dx.doi.org/10.1097/00000542-200512000-00029.

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Rathmell, James P., Timothy J. Brennan, and Philippe Richebé. "Pulsed Radiofrequency." Anesthesiology 103, no. 6 (December 1, 2005): 1313–14. http://dx.doi.org/10.1097/00000542-200512000-00030.

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Sluijter, Menno E. "Pulsed Radiofrequency." Anesthesiology 103, no. 6 (December 2005): 1313. http://dx.doi.org/10.1097/00000542-200512010-00029.

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Rathmell, James P., Timothy J. Brennan, and Philippe Richeb?? "Pulsed Radiofrequency." Anesthesiology 103, no. 6 (December 2005): 1313–14. http://dx.doi.org/10.1097/00000542-200512010-00030.

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18

Kwan, O. "Radiofrequency neurotomy." Journal of Neurology, Neurosurgery & Psychiatry 74, no. 8 (August 1, 2003): 1164—a—1165. http://dx.doi.org/10.1136/jnnp.74.8.1164-a.

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Brunello, Franco, Alessandro Cantamessa, Silvia Gaia, Patrizia Carucci, Emanuela Rolle, Anna Castiglione, Giovannino Ciccone, and Mario Rizzetto. "Radiofrequency ablation." European Journal of Gastroenterology & Hepatology 25, no. 7 (July 2013): 842–49. http://dx.doi.org/10.1097/meg.0b013e32835ee5f1.

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Bogduk, Nikolai. "Pulsed Radiofrequency." Pain Medicine 7, no. 5 (September 2006): 396–407. http://dx.doi.org/10.1111/j.1526-4637.2006.00210.x.

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Sluijter, Menno E., and Maarten van Kleef. "Pulsed Radiofrequency." Pain Medicine 8, no. 4 (May 2007): 388–89. http://dx.doi.org/10.1111/j.1526-4637.2007.00304.x.

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Munavalli, Girish (Gilly), James Childs, and Edward Victor Ross. "Radiofrequency Microneedling." Advances in Cosmetic Surgery 3, no. 1 (June 2020): 25–38. http://dx.doi.org/10.1016/j.yacs.2020.02.001.

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Golovac, Stanley. "Radiofrequency Neurolysis." Neuroimaging Clinics of North America 20, no. 2 (May 2010): 203–14. http://dx.doi.org/10.1016/j.nic.2010.02.007.

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Curley, Steven A., and Francesco Izzo. "Laparoscopic Radiofrequency." Annals of Surgical Oncology 7, no. 2 (March 2000): 78–79. http://dx.doi.org/10.1007/s10434-000-0078-x.

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Polder, Kristel D., and Suzanne Bruce. "Radiofrequency: Thermage." Facial Plastic Surgery Clinics of North America 19, no. 2 (May 2011): 347–59. http://dx.doi.org/10.1016/j.fsc.2011.04.006.

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Weiner, Steven F. "Radiofrequency Microneedling." Facial Plastic Surgery Clinics of North America 27, no. 3 (August 2019): 291–303. http://dx.doi.org/10.1016/j.fsc.2019.03.002.

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Alexiades, Macrene. "Microneedle Radiofrequency." Facial Plastic Surgery Clinics of North America 28, no. 1 (February 2020): 9–15. http://dx.doi.org/10.1016/j.fsc.2019.09.013.

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Rosenthal, Daniel I. "Radiofrequency Treatment." Orthopedic Clinics of North America 37, no. 3 (July 2006): 475–84. http://dx.doi.org/10.1016/j.ocl.2006.05.004.

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Smith, Timothy L., and James M. Smith. "Radiofrequency electrosurgery." Operative Techniques in Otolaryngology-Head and Neck Surgery 11, no. 1 (March 2000): 66–70. http://dx.doi.org/10.1016/s1043-1810(00)80016-0.

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Meknas, Khaled, Åshild Odden-Miland, James B. Mercer, Miguel Castillejo, and Oddmund Johansen. "Radiofrequency Microtenotomy." American Journal of Sports Medicine 36, no. 10 (June 16, 2008): 1960–65. http://dx.doi.org/10.1177/0363546508318045.

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Background Recalcitrant lateral epicondylitis (elbow tendinosis) is a common cause of elbow pain. There are many forms of treatment, none being superior. Hypothesis The main hypothesis tested in this study is that radiofrequency microtenotomy offers better results than the extensor tendon release and repair operation for elbow tendinosis, especially earlier recovery. Study Design Randomized controlled trial; Level of evidence, 1. Methods Twenty-four patients were randomized into 2 treatment groups, extensor tendon release and repair, and microtenotomy. Dynamic infrared thermography (DIRT) was employed as an objective method to verify the diagnosis as well as to document the outcome 3 months after the surgical procedure. Results Visual analog scale pain scores in the microtenotomy but not in the release group decreased significantly after 3 weeks. There was no statistically significant difference in pain scores between the 2 groups at 3, 6, and 12 weeks, and at 10 to 18 months. At 12 weeks, grip strength had improved significantly in the microtenotomy but not in the release group. The functional score was significantly increased in both groups. The DIRT group showed significant differences in epicondyle skin temperature between diseased and normal elbows both pre- and postoperatively. Abnormal DIRT images correlated well with elevated pain scores. Conclusions Radiofrequency microtenotomy provides a promising alternative to the release operation for elbow tendinosis. Dynamic infrared thermography provides a reliable, noninvasive, objective method for the diagnosis of elbow tendinosis, as well as for evaluation of the outcome following treatment.
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JONES, TERRY L. "Radiofrequency Identification." CIN: Computers, Informatics, Nursing 30, no. 9 (September 2012): 463–72. http://dx.doi.org/10.1097/nxn.0b013e3182545418.

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&NA;. "Radiofrequency Identification." CIN: Computers, Informatics, Nursing 30, no. 9 (September 2012): 473–74. http://dx.doi.org/10.1097/nxn.0b013e31826fa162.

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Healey, Terrance T., and Damian E. Dupuy. "Radiofrequency Ablation." Cancer Journal 17, no. 1 (January 2011): 33–37. http://dx.doi.org/10.1097/ppo.0b013e318209176f.

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Wu, Hanping, Agata A. Exner, Tianyi M. Krupka, Brent D. Weinberg, Ravi Patel, and John R. Haaga. "Radiofrequency Ablation." Academic Radiology 16, no. 3 (March 2009): 321–31. http://dx.doi.org/10.1016/j.acra.2008.09.008.

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35

Klitzner, Thomas S. "Radiofrequency Ablation." American Journal of Diseases of Children 147, no. 7 (July 1, 1993): 769. http://dx.doi.org/10.1001/archpedi.1993.02160310071021.

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Tanabe, Kenneth K., Steven A. Curley, Gerald D. Dodd, Allan E. Siperstein, and S. Nahum Goldberg. "Radiofrequency ablation." Cancer 100, no. 3 (2004): 641–50. http://dx.doi.org/10.1002/cncr.11919.

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Cheng, Yu-Chung Norman, and E. Mark Haacke. "Radiofrequency Excitation." Current Protocols in Magnetic Resonance Imaging 14, no. 1 (December 2007): B2.2.1—B2.2.11. http://dx.doi.org/10.1002/0471142719.mib0202s14.

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Carruthers, Alastair. "Radiofrequency Resurfacing." Facial Plastic Surgery Clinics of North America 9, no. 2 (May 2001): 311–19. http://dx.doi.org/10.1016/s1064-7406(23)00405-4.

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Kozlovaitė, Vilma, Pranas Grybauskas, Jūratė Cimbolaitytė, Aušra Mongirdienė, Vytautas Šileikis, Vytautas Zabiela, Joana Kažanienė, and Julius Ptašekas. "Coagulation alterations in treating arrhythmias with radiofrequency ablation." Medicina 45, no. 9 (September 8, 2009): 706. http://dx.doi.org/10.3390/medicina45090092.

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Objective. To determine an influence of radiofrequency ablation on changes in coagulation system. Material and methods. We investigated 30 patients with cardiac arrhythmias. Platelet aggregation, fibrinogen and D-dimer level were analyzed before, right after, 24 and 72 h after radiofrequency ablation. Platelet aggregation was explored in whole blood and platelet-rich plasma using adenosine diphosphate (ADP), epinephrine, and collagen for induction. Results. Platelet aggregation induced by ADP and collagen in whole blood plasma increased significantly (P<0.01) (by 45% and 43%, respectively) in 24 h after radiofrequency ablation and remained increased in 72 h after radiofrequency ablation (by 11% and 35%, respectively) (P<0.01) as compared with baseline results. Spontaneous aggregation of platelet-rich plasma as well as ADP- and collagen-induced platelet aggregation tended to decrease right after radiofrequency ablation. Epinephrine-induced platelet aggregation significantly decreased by 17.5% after radiofrequency ablation (P<0.01) and started to increase in 24 h after radiofrequency ablation. In 72 h after radiofrequency ablation, platelet aggregation induced by different agonists increased by 7–45% significantly (P<0.05), and values were higher than baseline ones. Fibrinogen level after radiofrequency ablation did not differ from that of the baseline (3.08±0.7 g/L), but D-dimer level increased significantly (from 0.39±0.3 to 1.29±2.4 mg/L, P<0.01). In 24 h after radiofrequency ablation, an increase in fibrinogen level and a decrease in D-dimer level were found. Fibrinogen level increased to 3.32±0.6 g/L significantly in 72 h after radiofrequency ablation (P<0.05). Meanwhile, D-dimer concentration decreased to 0.78±0.8 mg/L, but it was still significantly higher (P<0.05) than the baseline value. Conclusion. Despite diminished platelet aggregation and increased D-dimer level right after radiofrequency ablation, a risk of thrombosis increased in the next few days after radiofrequency ablation.
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Arsanious, David. "Pulsed Dose Radiofrequency Before Ablation of Medial Branch of the Lumbar Dorsal Ramus for Zygapophyseal Joint Pain Reduces Postprocedural Pain." Pain Physician 7;19, no. 7;9 (September 14, 2016): 477–84. http://dx.doi.org/10.36076/ppj/2016.19.477.

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Background: One of the potential side effects with radiofrequency ablation (RFA) includes painful cutaneous dysesthesias and increased pain due to neuritis or neurogenic inflammation. This pain may require the prescription of opioids or non-opioid analgesics to control post-procedural pain and discomfort. Objectives: The goal of this study is to compare post-procedural pain scores and post-procedural oral analgesic use in patients receiving continuous thermal radiofrequency ablation versus patients receiving pulsed dose radiofrequency immediately followed by continuous thermal radiofrequency ablation for zygopophaseal joint disease. Study Design: This is a prospective, double-blinded, randomized, controlled trial. Patients who met all the inclusion criteria and were not subject to any of the exclusion criteria were required to have two positive diagnostic medial branch blocks prior to undergoing randomization, intervention, and analysis. Setting: University hospital. Methods: Eligible patients were randomized in a 1:1 ratio to either receive thermal radiofrequency ablation alone (standard group) or pulsed dose radiofrequency (PDRF) immediately followed by thermal radiofrequency ablation (investigational group), all of which were performed by a single Board Certified Pain Medicine physician. Post-procedural pain levels between the two groups were assessed using the numerical pain Scale (NPS), and patients were contacted by phone on postprocedural days 1 and 2 in the morning and afternoon regarding the amount of oral analgesic medications used in the first 48 hours following the procedure. Results: Patients who received pulsed dose radiofrequency followed by continuous radiofrequency neurotomy reported statistically significantly lower post-procedural pain scores in the first 24 hours compared to patients who received thermal radiofrequency neurotomy alone. These patients also used less oral analgesic medication in the post-procedural period. Limitations: These interventions were carried out by one board accredited pain physician at one center. The procedures were exclusively performed using one model of radiofrequency generator, at one setting for the PDRF and RFA. The difference in the number of levels of ablation was not considered in the analysis of the results. Conclusion: Treating patients with pulsed dose radiofrequency prior to continuous thermal radiofrequency ablation can provide patients with less post-procedural pain during the first 24 hours and also reduce analgesic requirements. Furthermore, the addition of PDRF to standard thermal RFA did not prolong the time of standard thermal radiofrequency ablation procedures, as it was performed during the typically allotted time for local anesthetic action. Key words: Low back pain, facet joint disease, medial branch block, Radiofrequency ablation, thermal radiofrequency, pulsed dose radiofrequency, PDRF, zygapophyseal joint
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Kääb, Max J., Herman J. Bail, Andreas Rotter, Pierre Mainil-Varlet, Iolo apGwynn, and Andreas Weiler. "Monopolar Radiofrequency Treatment of Partial-Thickness Cartilage Defects in the Sheep Knee Joint Leads to Extended Cartilage Injury." American Journal of Sports Medicine 33, no. 10 (October 2005): 1472–78. http://dx.doi.org/10.1177/0363546505275013.

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Background The application of radiofrequency energy to smooth and stabilize the cartilage surface has become increasingly controversial. There is little knowledge on extended-term effects, such as cartilage viability. Purpose To analyze the effect of radiofrequency treatment on artificially created partial-thickness defects in the femoral cartilage of sheep knee joints 24 weeks after surgery. Study Design Controlled laboratory study. Methods Grade II cartilage surface defects on the medial and lateral femoral condyles were artificially created in sheep for in vivo analysis. The cartilage lesions were treated alternately on the lateral or the medial condyle using a monopolar radiofrequency probe. Radiofrequency treatment was performed in a freehand technique until surface smoothing without change of cartilage color was seen. At 24 weeks after surgery, cartilage samples were harvested and were processed for macroscopic and histological evaluation. To analyze the effect of radiofrequency at time zero, samples of sheep femoral condyle cartilage with and without artificially created clefts were treated in vitro with radiofrequency. Evaluation was performed by scanning electron and confocal microscopy. Results At 24 weeks after surgery, grade IV cartilage defects were detected in all radiofrequency-treated samples. The histological findings showed a central ulcer and dead chondrocytes in the radiofrequency-treated regions. The radiofrequency-treated cartilage revealed partial surface irregularities with partial-defect repair. After radiofrequency treatment in vitro, samples at time zero showed smoothing of the artificially created clefts, as seen by scanning electron microscopy. Confocal microscopy showed necrosis of chondrocytes over approximately one fourth of the upper cartilage thickness. Conclusion Even if chondrocyte death is seen only in approximately one fourth of the upper cartilage layers in the sheep femur after in vitro application, radiofrequency treatment can cause damage to cartilage 24 weeks after application. Clinical Relevance Caution is recommended in the application of monopolar radiofrequency energy by visual control to partialthickness cartilage defects. Irregular fronds of chondromalacia may be unattractive but represent viable articular cartilage. Using radiofrequency to obtain a more visually pleasing smooth surface may be counterproductive.
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Yang, Aaron J., Graham Wagner, Taylor Burnham, Zachary L. McCormick, and Byron J. Schneider. "Radiofrequency Ablation for Chronic Posterior Sacroiliac Joint Complex Pain: A Comprehensive Review." Pain Medicine 22, Supplement_1 (July 1, 2021): S9—S13. http://dx.doi.org/10.1093/pm/pnab021.

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Abstract Radiofrequency ablation of the sacral lateral branches targets the innervation of the posterior sacroiliac ligaments and posterior portion of the sacroiliac joint. These structures are also collectively referred to as the posterior sacroiliac joint complex. This review will discuss current diagnostic block paradigms and selection criteria for sacral lateral branch radiofrequency ablation, varying techniques and technologies utilized for sacral lateral branch radiofrequency ablation, and updates on the clinical outcome literature. The current evidence suggests that sacral lateral branch radiofrequency ablation can provide relief for posterior sacroiliac joint complex pain, but the literature is limited by variability in selection criteria, the specific nerves targeted by radiofrequency ablation, and the types of radiofrequency ablation technology and techniques utilized in clinical outcome studies.
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Alzahrani, Meshari A., Omar Safar, Muath Almurayyi, Abdulaziz Alahmadi, Abdulrahman M. Alahmadi, Muhannad Aljohani, Abdalah E. Almhmd, et al. "Pulsed Radiofrequency Ablation for Orchialgia—A Literature Review." Diagnostics 12, no. 12 (November 27, 2022): 2965. http://dx.doi.org/10.3390/diagnostics12122965.

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Pulsed radiofrequency, short bursts of radiofrequency energy, has been used by pain practitioners as a non- or minimally neurodestructive technique, an alternative to radiofrequency heat lesions. The clinical advantages and mechanisms of this treatment remain unclear. To review the current clinical implication of the pulsed radiofrequency technique for male patients with chronic scrotal pain. We systematically searched the English literature available at the EMBASE, MEDLINE/PubMed, Google Scholar, and Cochrane Library from inception to 22 November 2022. Only reports on a pulsed radiofrequency application on male patients with chronic scrotal pain were included. The final analysis yielded six reports on the clinical use of pulsed radiofrequency applications in male patients with chronic scrotal pain: six full publications, three case reports, one case series, one prospective uncontrolled pilot study, and one prospective randomized, controlled clinical trial. The accumulation of these data shows that using pulsed radiofrequency generates an increasing interest in pain physicians, radiologists, and urologists for managing chronic scrotal pain. No side effects related to the pulsed radiofrequency technique were reported to date. Further research on the clinical and biological effects is justified. Large sample sizes and randomized clinical trials are warranted.
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Vallejo, Ricardo, Ramsin M. Benyamin, and Luis Aliaga. "Radiofrequency vs. pulse radiofrequency: The end of the controversy." Techniques in Regional Anesthesia and Pain Management 14, no. 3 (July 2010): 128–32. http://dx.doi.org/10.1053/j.trap.2010.06.003.

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Häcker, A., F. Risse, K. Peters, S. Vallo, P. Alken, J. Jenne, and M. S. Michel. "BIPOLAR RADIOFREQUENCY ABLATION: A TECHNICAL ADVANCEMENT IN RADIOFREQUENCY TECHNOLOGY." European Urology Supplements 5, no. 2 (April 2006): 218. http://dx.doi.org/10.1016/s1569-9056(06)60789-6.

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Van Zundert, Jan, Anton J. A. de Louw, Elbert A. J. Joosten, Alfons G. H. Kessels, Wiel Honig, Pieter J. W. C. Dederen, Jan G. Veening, Johan S. H. Vles, and Maarten van Kleef. "Pulsed and Continous Radiofrequency Current Adjacent to the Cervical Dorsal Root Ganglion of the Rat Induces Late Cellular Activity in the Dorsal Horn." Anesthesiology 102, no. 1 (January 1, 2005): 125–31. http://dx.doi.org/10.1097/00000542-200501000-00021.

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Background Pulsed radiofrequency treatment has recently been described as a non-neurodestructive or minimally neurodestructive alternative to radiofrequency heat lesions. In clinical practice long-lasting results of pulsed radiofrequency treatment adjacent to the cervical dorsal root ganglion for the management of chronic radicular spinal pain have been reported without neurologic complications. However, the mode of action is unclear. An early (3 h) effect of pulsed radiofrequency as measured by an increase of c-Fos in the pain-processing neurons of the dorsal horn of rats has been described in the literature. This effect was not mediated by tissue heating. The authors investigated a possible late or long-term effect of three different radiofrequency modalities. Methods Cervical laminectomy was performed in 19 male Wistar rats. The cervical dorsal root ganglion was randomly exposed to one of the four interventions: sham, continuous radiofrequency current at 67 centigrades, or pulsed radiofrequency current for 120 s or 8 min. The animals were sacrificed and the spinal cord was prepared for c-Fos labeling 7 days after the intervention. Results The number of c-Fos immunoreactive cells in the dorsal horn was significantly increased in the three different radiofrequency modalities as compared with sham. No significant difference was demonstrated between the three active intervention groups. Conclusions The authors demonstrated a late neuronal activity in the dorsal horn after exposure of the cervical dorsal root ganglion to different radiofrequency modalities, which was not temperature dependent.
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47

Tayyaba Wasim, Syed Mehmood Ali, Zahra Asad, Anum Zeb, Muhammad Oun, and Zulqarnain Butt. "Treatment of chronic sacroiliac joint pain using Conventional Radiofrequency (CRF) and Pulsed Radiofrequency (PRF): A randomized control study." Professional Medical Journal 31, no. 04 (April 1, 2024): 537–44. http://dx.doi.org/10.29309/tpmj/2024.31.04.8026.

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Objective: To determine the effectiveness of conventional radiofrequency (CRF) and pulsed radiofrequency (PRF) in treatment of chronic sacroiliac joint pain. Study Design: Randomized Controlled Trial. Setting: Shaikh Zayed Hospital, Lahore. Period: 2nd August 2022 to 10th February 2023. Methods: A total sample of 60 patients with SIJ pain was screened for this study. This sample was divided equally but randomly into both study groups; conventional radiofrequency (CRF) and pulsed radiofrequency (PRF). Pre-procedure general information on Visual analogue score (VAS) and revised Oswestry Disability Index (ODI) were used to measure the main outcome variables; pain score and physical disability index. Post-procedure information on these two outcome variables was also recorded after 1, 3 and 6 months duration. Paired samples t-test and independent samples t-test was used to assess the effectiveness of these two treatment methods for SIJ pain treatment. Results: The mean pain score in the conventional radiofrequency (CRF) group was reduced to 3.02 ± 0.9 from 8.02 ± 1.13 which is more substantial and statistically significant than pulsed radiofrequency where it was 4.2± 1.31 from 7.98 ± 1.20. Similarly, the conventional radiofrequency (CRF) group showed better performance on average scores of the ODI index (20.2± 6.9) as compared to pulsed radiofrequency (31.2± 8.9) in reducing physical disability in SIJ patients. Conclusion: This study concludes that the existing conventional radiofrequency (CRF) method of treatment can be effectively used in treatment of SIJ with its slight complications.
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48

Trinidad, José Manuel, Ana Isabel Carnota, Inmaculada Failde, and Luis Miguel Torres. "Radiofrequency for the Treatment of Lumbar Radicular Pain: Impact on Surgical Indications." Pain Research and Treatment 2015 (August 16, 2015): 1–6. http://dx.doi.org/10.1155/2015/392856.

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Study Design. Quasiexperimental study. Objective. To investigate whether radiofrequency treatment can preclude the need for spinal surgery in both the short term and long term. Background. Radiofrequency is commonly used to treat lumbosacral radicular pain. Only few studies have evaluated its effects on surgical indications. Methods. We conducted a quasiexperimental study of 43 patients who had been scheduled for spinal surgery. Radiofrequency was indicated for 25 patients. The primary endpoint was the decision of the patient to reject spinal surgery 1 month and 1 year after treatment (pulsed radiofrequency of dorsal root ganglion, 76%; conventional radiofrequency of the medial branch, 12%; combined technique, 12%). The primary endpoint was the decision of the patient to reject spinal surgery 1 month and 1 year after treatment. In addition, we also evaluated adverse effects, ODI, NRS. Results. We observed after treatment with radiofrequency 80% of patients rejected spinal surgery in the short term and 76% in the long term. We conclude that radiofrequency is a useful treatment strategy that can achieve very similar outcomes to spinal surgery. Patients also reported a very high level of satisfaction (84% satisfied/very satisfied). We also found that optimization of the electrical parameters of the radiofrequency improved the outcome of this technique.
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Wang, Feng, Gang Chen, and Lin Wu. "Late effects of radiofrequency ablation lesions resulting in a progressive mitral valve perforation in a 2-month-old infant." Cardiology in the Young 29, no. 10 (September 2, 2019): 1297–99. http://dx.doi.org/10.1017/s1047951119001926.

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AbstractThere has been great concern with the use of radiofrequency ablation in infants since radiofrequency ablation lesions were shown to have a progressing nature in immature myocardium of animals. In this report, we present a 2-month-old infant with life-threatening medically refractory supraventricular tachycardia. Radiofrequency ablation successfully cured arrhythmia; however, late effects of radiofrequency ablation lesions resulted in a progressive mitral valve perforation requiring surgical repair.
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50

Tanigawa, N., S. Sawada, N. Morioka, T. Iwamiya, T. Senda, M. Kobayashi, Y. Okuda, and Y. Ohta. "Intraarterial Occlusion by Radiofrequency." Acta Radiologica 35, no. 6 (November 1994): 626–28. http://dx.doi.org/10.1177/028418519403500621.

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Arterial occlusion using radiofrequency energy was performed. The length of the noninsulated part of the guidewire was 10 mm and the duration of radiofrequency supply was 20 s. Animal experiments were carried out in 17 canine arteries; 4 out of 6 arteries less than 2.3 mm in diameter were completely occluded during the 20 s radiofrequency supply. A clinical application was also successfully performed without any complications. Arterial occlusion with radiofrequency can be applied to vessels less than about 2 mm in diameter.
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