Relevant bibliographies by topics / Radioisotope tracers in biochemistry

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Radioisotope tracers in biochemistry'

Author: Grafiati
Published: 4 June 2021
Last updated: 13 February 2022

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Journal articles on the topic "Radioisotope tracers in biochemistry"

1

Lappin, Graham. "A historical perspective on radioisotopic tracers in metabolism and biochemistry." Bioanalysis 7, no. 5 (2015): 531–40. http://dx.doi.org/10.4155/bio.14.286.

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Patterson, Kristine Y., and Claude Veillon. "Stable Isotopes of Minerals as Metabolic Tracers in Human Nutrition Research." Experimental Biology and Medicine 226, no. 4 (2001): 271–82. http://dx.doi.org/10.1177/153537020122600403.

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Enriched stable isotopes used as tracers have proven to be valuable in studies of the absorption and metabolism of minerals. Unlike radioisotopes, they can be used in high-risk population groups such as infants, children, and pregnant or lactating women. Estimates of mineral absorption can be made from the oral administration of a single tracer or from two tracers, one given orally and the other intravenously (IV). It is possible to determine the metabolism of the mineral with modeling based on the amount of the tracer or tracers in different biological samples. One of the key decisions in stu
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3

Bala, Gezim, Maxine Crauwels, Anneleen Blykers, et al. "Radiometal-labeled anti-VCAM-1 nanobodies as molecular tracers for atherosclerosis – impact of radiochemistry on pharmacokinetics." Biological Chemistry 400, no. 3 (2019): 323–32. http://dx.doi.org/10.1515/hsz-2018-0330.

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Abstract Radiolabeling of nanobodies with radiometals by chelation has the advantage of being simple, fast and easy to implement in clinical routine. In this study, we validated 68Ga/111In-labeled anti-VCAM-1 nanobodies as potential radiometal-based tracers for molecular imaging of atherosclerosis. Both showed specific targeting of atherosclerotic lesions in ApoE−/− mice. Nevertheless, uptake in lesions and constitutively VCAM-1 expressing organs was lower than previously reported for the 99mTc-labeled analog. We further investigated the impact of different radiolabeling strategies on the in v
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Papathemelis, Thomas, Evi Jablonski, Anton Scharl, et al. "Sentinel Lymph Node Biopsy in Breast Cancer Patients by Means of Indocyanine Green Using the Karl Storz VITOM® Fluorescence Camera." BioMed Research International 2018 (2018): 1–8. http://dx.doi.org/10.1155/2018/6251468.

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Currently, the use of radioisotope and blue dye for sentinel lymph node biopsy (SLNB) for axillary staging in breast cancer is common. Recently, indocyanine green (ICG) has been proposed as an alternative sentinel lymph node (SLN) tracking agent. We evaluated the clinical value of ICG as an additional tracer in combination with Technetium99mand as an alternative to Technetium99mfor the identification of SLN in 104 breast cancer patients. 21 patients had at least 1 histologically tumor-positive SLN. All 21 patients were detected by ICG; in one of these 21 sentinel-positive patients, Technetium9
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Kuemmerle, S. C., G. L. Boltinghouse, S. M. Delby, T. L. Lane, and R. P. Simondsen. "Automated Assay of Vitamin B-12 by the Abbott IMx® Analyzer." Clinical Chemistry 38, no. 10 (1992): 2073–77. http://dx.doi.org/10.1093/clinchem/38.10.2073.

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Abstract A nonisotopic assay of vitamin B-12 in human serum or plasma is described, performed with the Abbott IMx analyzer. The sample is first treated at pH > 12.5 to release bound vitamin B-12 and to convert all forms to cyanocobalamin. Next, the analyte is bound, at lower pH, by vitamin B-12-specific binding protein, immobilized to a solid phase of polymeric microspheres. Detection involves monitoring the activity of the tracer enzyme (alkaline phosphatase) coupled to a derivative of cyanocobalamin. Total assay precision is 7.9% for vitamin B-12 at 200 ng/L, 6.6% at 400 ng/L, and 6.7
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Donhoffer, D. K. "Guidebook on radioisotope tracers in industry." International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes 42, no. 8 (1991): 777. http://dx.doi.org/10.1016/0883-2889(91)90184-3.

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Smith, D. B. "Guide book on radioisotope tracers in industry." Journal of Hydrology 125, no. 1-2 (1991): 159. http://dx.doi.org/10.1016/0022-1694(91)90089-z.

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Wilson, Mark. "Radioisotope Tracers Reveal Extensive Melting in Earth’s Distant Past." Physics Today 58, no. 9 (2005): 19–21. http://dx.doi.org/10.1063/1.2117809.

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Oh, Min-Seok, Sung-Hee Jung, and Seong-Ho Choi. "Synthesis and characterization of coordination polymer nanoparticles as radioisotope tracers." Applied Radiation and Isotopes 85 (February 2014): 19–22. http://dx.doi.org/10.1016/j.apradiso.2013.11.026.

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10

Reichard, George. "Tracers in Metabolic Research: Radioisotope and Stable Isotope/Mass Spectromctry Methods." Clinical Nuclear Medicine 10, no. 4 (1985): 315–16. http://dx.doi.org/10.1097/00003072-198504000-00023.

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Dissertations / Theses on the topic "Radioisotope tracers in biochemistry"

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Chai, Yingtao. "Study of particle movement in the nearshore region of Lake Superior with radioisotope tracers /." Available online. Click here, 2005. http://sunshine.lib.mtu.edu/ETD/DISS/chaiy/ChaiDiss.pdf.

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Correchel, Vladia. ""Avaliação de índices de erodibilidade do solo através da técnica da análise da redistribuição do "fallout" do 137Cs"." Universidade de São Paulo, 2004. http://www.teses.usp.br/teses/disponiveis/64/64132/tde-13042004-111210/.

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Entre os parâmetros da USLE (Universal Soil Loss Equation), método mais utilizado na estimativa das perdas de solo por erosão hídrica, a erodibilidade do solo, representada pelo fator K e definida como a taxa de solo perdida por unidade de índice de erosividade, em parcela unitária considerada como padrão (Wischmeier et al., 1971), é o único intrínseco ao solo. Nessas condições padrão o valor encontrado é considerado como o real valor de K. Pelas dificuldades experimentais para obtenção do valor de K para todos os solos, esse fator é geralmente estimado por equações matemáticas empíricas com b
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Buchheister, Andre. "Stable Isotope Dynamics in Summer Flounder Tissues, with Application to Dietary Assessments in Chesapeake Bay." W&M ScholarWorks, 2008. http://www.vims.edu/library/Theses/Buchheister08.pdf.

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DeTurk, Kenneth Wayne. "Optimum ¹¹¹In okine labelled autologous leukocytes." Scholarly Commons, 1989. https://scholarlycommons.pacific.edu/uop_etds/2187.

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The purpose of this study is to determine the optimum conditions for obtaining a leukocyte button which most effectively will be subsequently labelled with 111In oxine. As in all radiopharmaceuticals, the highest radiopharmaceutical purity, or the fraction of total radioactivity in the desired radiopharmaceutical form (111In oxine leukocyte), the better the product. Many 111In ocine labelled leukocytes are contaminated by labelled platelets, red cells, and proteins, resulting in a “dirty” product. But with careful leukocyte culturing, sedimentation, centrifugation, and labelling, as demonstrat
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Andersson, Ken G. "Combinatorial Protein Engineering Of Affibody Molecules Using E. Coli Display And Rational Design Of Affibody-Based Tracers For Medical Imaging." Doctoral thesis, KTH, Proteinteknologi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-213451.

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Directed evolution is today an established strategy for generation of new affinity proteins. This thesis describes the development of a cell-display method using Escherichia coli for directed evolution of Affibody molecules. Further, the thesis describes rational design of Affibody-based tracers, intended for future patient stratification using medical imaging. Fusing recombinant proteins to various autotransporters is a promising approach for efficient surface display on the surface of E. coli, as well as for construction of high-complexity libraries. In paper I, we successfully engineered an
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Grimaldo, Morón José Teófilo. "Contribution à la synthèse de macrocycles tétraphosphorés : ligands polydentates présentant un intérêt biomédical." Grenoble 1, 1987. http://www.theses.fr/1987GRE10161.

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Synthese de ligands macrocycles tetraphores, complexants potentiels de cations paramagnetiques (gd**(3+), fe**(3+)) et de nucleide radioactifs. Etude de la reactivite de ces ligands et des essais de complexation
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Fine, David Robert. "The use of anatomically based models for the analysis of imaged tracer experiments in humans." Thesis, 1994. https://hdl.handle.net/10539/23778.

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A thesis submitted to the faculty of Engineering, University of the Witwatersrand, Johannesburg , in fulfillment of the requirements for the degree of Doctor of Philosophy. Johannesburg, November 1994<br>Organ function is often characterised using imaging techniques. In particular a tracer is often used which does not react with tissue, is low in concentration, follows body fluid flows and is distinguishable from the observed system and thus measurable. These requirements ensure linear characteristics of the tracer. In this thesis, these linear characteristics are used to develop a genera
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Books on the topic "Radioisotope tracers in biochemistry"

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N, Shamin A., ed. Mechenye atomy v biokhimii: Istoricheskiĭ ocherk. "Nauka", 1988.

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2

1965-, Chinkes David L., and Wolfe Robert R, eds. Isotope tracers in metabolic research: Principles and practice of kinetic analysis. 2nd ed. Wiley-Liss, 2005.

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R, Wolfe Robert, ed. Radioactive and stable isotope tracers in biomedicine: Principles and practice of kinetic analysis. Wiley-Liss, 1992.

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David, Foster, and Toffolo Gianna, eds. Tracer kinetics in biomedical research: From data to model. Kluwer Academic/Plenum, 2000.

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1946-, Burns H. Donald, ed. Nuclear imaging in drug discovery, development, and approval. Birkhäuser, 1993.

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6

Anthony, Evans E., Oldham K. G, and Society of Chemical Industry (Great Britain), eds. Radiochemicals in biomedical research. Published on behalf of the Society of Chemical Industry by Wiley, 1988.

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7

Guidebook on radioisotope tracers in industry. International Atomic Energy Agency, 1990.

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8

BUNCEL, E. Synthesis And Applications Of Isotopically Labelled Compounds 1991. Elsevier Science Publishing Company, 1992.

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9

Synthesis and applications of isotopically labelled compounds, 1991: Proceedings of the fourth international symposium, Toronto, Canada, 3-7 September 1991. Elsevier, 1992.

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10

International Atomic Energy Agency; IAEA. Guidebook on Radioisotope Tracers in Industry (Technical Reports Series (International Atomic Energy Agency)). Intl Atomic Energy Agency, 1990.

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Book chapters on the topic "Radioisotope tracers in biochemistry"

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Johnson, P. "Measurement of flow using radioactive tracers." In Radioisotope Techniques for Problem-Solving in Industrial Process Plants. Springer Netherlands, 1986. http://dx.doi.org/10.1007/978-94-009-4073-4_8.

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2

Suman, Shishu Kant, Rohit Sharma, and Chandan Kumar. "Principle and Applications of Immunodiagnostics Using Radioisotope as Tracers." In Immunodiagnostic Technologies from Laboratory to Point-Of-Care Testing. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-5823-8_3.

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Slater, R. J. "Radioisotope techniques." In Principles and Techniques of Biochemistry and Molecular Biology. Cambridge University Press, 2005. http://dx.doi.org/10.1017/cbo9780511813412.015.

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"IMMUNOLOGICAL AND RADIOISOTOPE TECHNIQUES." In Clinical Biochemistry: Techniques and Instrumentation. WORLD SCIENTIFIC, 2001. http://dx.doi.org/10.1142/9789812810236_0013.

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Provan, Drew. "Nuclear medicine." In Oxford Handbook of Clinical and Laboratory Investigation, edited by Drew Provan. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198766537.003.0014.

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Nuclear medicine is a rapidly evolving branch of medical imaging, which uses radionuclides or radiopharmaceuticals for diagnostic and therapeutic purposes. Nuclear medicine techniques employ a carrier molecule, selected to target the organ/tissue of interest, tagged with a gamma-emitting radioisotope. Nuclear medicine procedures can detect early physiological responses to disease processes, generally before structural changes have taken place. Characterization of abnormalities often relies upon pattern recognition within a particular clinical setting. In this chapter, various procedures and tracers (single photon emission computed tomography (SPECT) and positron emission tomography (PET)) used in nuclear medicine are described in a systematic way, including their common indications, interpretation criteria, advantages, and pitfalls with classical examples.
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Conference papers on the topic "Radioisotope tracers in biochemistry"

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Ugolini, Daniele, Francesco Rossi, and Francesco Basile. "Decommissioning of the Radio Chemical Hot Laboratory of the European Commission Joint Research Centre of Ispra." In ASME 2011 14th International Conference on Environmental Remediation and Radioactive Waste Management. ASMEDC, 2011. http://dx.doi.org/10.1115/icem2011-59207.

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The construction of the Radio Chemical Hot Laboratory (RCHL) of the Joint Research Centre (JRC) of Ispra began in the early 1960s while the laboratory activities started in 1964. In 1976 an annex to the main building was built. At this time the RCHL main research activities were in environment and biochemistry by means of radioactive tracers; neutron activation analyses; extraction of actinides from radioactive liquid waste coming from the nuclear fuel reprocessing plants; and analyses of U, Pu, and Th in samples from the nuclear fuel cycle in order to determine the isotopic ratio and the burn
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