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Dissertations / Theses on the topic 'Radioisotopes'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

PUPILLO, Gaia. "Radioisotopes production via accelerator for nuclear medicine applications." Doctoral thesis, Università degli studi di Ferrara, 2014. http://hdl.handle.net/11392/2388938.

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2

Egorov, Oleg B. "Automation of radionuclide separations and analysis by flow injection techniques /." Thesis, Connect to this title online; UW restricted, 1998. http://hdl.handle.net/1773/11617.

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3

Hou, Xinchi. "Cyclotron-based production of radioisotopes for medical imaging studies." Thesis, University of British Columbia, 2014. http://hdl.handle.net/2429/50862.

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The cyclotron-based ¹⁰⁰Mo(p,2n)⁹⁹mTc reaction has been proposed as an alternative method for solving the recent shortage of ⁹⁹mTc, which is the most commonly used radioisotope in nuclear medicine. With this production method, however, even if highly enriched molybdenum is used, various radioactive and stable isotopes can be produced simultaneously with ⁹⁹mTc and they may affect the diagnostic outcome and radiation dosimetry in human studies. The objective of this thesis was to investigate the feasibility of the cyclotron-based production of ⁹⁹mTc. Towards this aim, theoretical predictions and

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4

Sitarz, Mateusz. "Research on production of new medical radioisotopes with cyclotron." Thesis, Nantes, 2019. http://www.theses.fr/2019NANT4050.

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Aujourd’hui, les radio-isotopes sont fréquemment utilises en médecine, pour le diagnostic et la thérapie. Cependant, le développement constant de la médecine nucléaire provoque l’application de nouveaux radio-isotopes médicaux. La recherche sur leur production possible a grande échelle est la première étape d’un long processus d’études avant de pouvoir de les utilise dans des essais cliniques. Dans cette thèse, les voies de production ont été étudiées pour la formation de médicalement intéressants 43Sc, 44m,gSc, 47Sc, 97Ru et 105Rh en utilisant de cyclotrons. Les radioisotopes de scandium ont

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5

de, Sousa Fernando Nuno. "Movement of radionuclides through unsaturated soils." Diss., Georgia Institute of Technology, 1985. http://hdl.handle.net/1853/17875.

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6

Pan, Xiaodi. "Radioisotopes in Domestic Wastewater and Their Fate in Wastewater Treatment." Digital WPI, 2016. https://digitalcommons.wpi.edu/etd-theses/1247.

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"Modern medical therapies involving radioisotopes provide radionuclide contamination in wastewater. These radioisotopes present in wastewater increase the possibility of human exposure to radiation. The objective of this work was to study the fate of radionuclides of medical sources in wastewater, and to determine the distribution of various radionuclides in different stages of wastewater treatment. Influent, return activated sludge and effluent samples were collected from four wastewater facilities in Massachusetts. Samples were collected approximately twice a month over 4 months. The radionu

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7

Naidoo, Clive. "Selective separation of elements and radioisotopes by ion exchange chromatography." Thesis, Stellenbosch : Stellenbosch University, 2002. http://hdl.handle.net/10019.1/53046.

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Thesis (PhD)--Stellenbosch University, 2002.<br>ENGLISH ABSTRACT: The equilibrium distribution coefficients of 32 metal ions [Al(llI), As(V), CdïIl), Ce(III), Ce(IV), Co(n), Cr(III), Cu(II), Fe(III), Ga(III), Ge(IV), !n(III), La(III), Mn(II), Mo(VI), Nb(V), Ni(II), Pr(III), Sb(V), Sc(III), Se(IV), Sn(IV), Ta(V), Tb(III), Te(IV), Ti(IV), Vev), W(VI), Y(III), Yb(III), Zn(lI) and Zr(IV)] on a cation exchanger (Bio- Rad® AG50W-X8) and an anion exchanger (Bio-Rad® AG1-X8) in varying oxalic acid - sulphuric acid mixtures were successfully determined. The equilibrium distribution coefficients o

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8

MARTINI, Petra. "High-Yield Cyclotron Production of Metallic Radioisotopes for Nuclear Medicine." Doctoral thesis, Università degli studi di Ferrara, 2018. http://hdl.handle.net/11392/2487885.

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The main purpose of LARAMED project (LAboratoty of Radioisotopes for MEDicine), founded at LNL-INFN, is the R&D on cyclotron production of conventional, such as Tc-99m (TECHN-OSP projects), and emerging, such as Cu-67 (COME project), metallic medical radioisotopes. The aim of my PhD has been the development, optimization and automation of post-irradiation target processing systems, enabling to recover in high yield highly pure radioisotopes (RI), one of the most critical steps in the RI cyclotron production. The possibility of a reactor-produced molybdenum-99 shortage, used as parent nuclide o

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9

Curtis, Nicola. "Tritium NMR studies of protein-ligand interactions." Thesis, University of Surrey, 1994. http://epubs.surrey.ac.uk/842983/.

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Tritium NMR studies provide a convenient way of obtaining detailed information about conformational equilibria, dynamic processes and specific interactions in protein-ligand complexes provided that suitably 3H-labelled molecules are available. In this study [7,9-3H]- and [3',5',7-3H]folic acid, and [3',5',7-3H]methotrexate were synthesised and the NMR spectra of their complexes with Lactobacillus casei dihydrofolate reductase (DHFR) were assigned and analysed as a function of pH (DHFR-folate complexes) and temperature (DHFR-methotrexate complexes). From these data it was possible to obtain fur

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10

Valsborg, Jacob Stenmann. "Design and synthesis of radioligands in drug development /." [Cph.] : Royal danish School of Pharmacy, Department of Medicinal Chemistry, 2002. http://www.dfh.dk/phd/defences/jacobvalsborg.htm.

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11

Majibur, Rahman Mohammad. "Development of Analytical Strategies to Measure Radioisotopes of Tin in the Environment." Thesis, Université d'Ottawa / University of Ottawa, 2018. http://hdl.handle.net/10393/38606.

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Quantification of tin isotopes in environmental samples, particularly the radioactive 126Sn, is important for processes such as the biomonitoring of organotin species, long-term nuclear waste storage and treatment planning. The detection of 126Sn by mass spectrometric methods is, however, hampered by the presence of the stable 126Te isotope. Therefore, separation of tin from tellurium is crucial to minimize isobaric interferences that limit the quantification of 126Sn by Accelerator Mass Spectrometry (AMS) and other instrumental techniques. In the present study, three major accomplishments are

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12

Jensen, M., T. Eriksson, G. Severin, M. Parnaste, and J. Norling. "Experimental yields of PET radioisotopes from a prototype 7.8 MeV cyclotron." Helmholtz-Zentrum Dresden - Rossendorf, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:d120-qucosa-166159.

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Introduction The worldwide use of PET has proven beyond dispute the importance for both routine diagnosis and physiological, oncological and pharmacological research. In many ways the present success of PET relies on the mature technology of PET compact medical cyclotrons. As long time developers of new targets, isotopes and com-pounds, we have been inclined to look for new block-buster applications, high power targets and sustainable ways of embracing the GMP and regional distribution, but recent pioneering development [1] around very small cyclotrons and “embedded synthesis and qc” has point

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13

Lerner, Paul (Paul Edmund). "Scavenging and transport of thorium radioisotopes in the North Atlantic Ocean." Thesis, Massachusetts Institute of Technology, 2018. http://hdl.handle.net/1721.1/119989.

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Thesis: Ph. D., Joint Program in Oceanography/Applied Ocean Science and Engineering (Massachusetts Institute of Technology, Department of Earth, Atmospheric, and Planetary Sciences; and the Woods Hole Oceanographic Institution), 2018.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (pages 321-351).<br>Many chemical constituents are removed from the ocean by attachment to settling particles, a process referred to as "scavenging." Radioisotopes of thorium, a highly particle-reactive element, have been used extensively to study scavenging in the ocean. However, thi

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14

Remonato, Isabelle. "Les radioisotopes et leurs utilisations thérapeutiques : applications dans les explorations fonctionnelles." Strasbourg 1, 1988. http://www.theses.fr/1988STR15089.

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15

Chen, Ji. "Quantitative cardiac spect in the presence of changing radionuclide distributions." Diss., Georgia Institute of Technology, 2002. http://hdl.handle.net/1853/17941.

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16

Vermeulen, Christiaan. "The production of ¹³⁹Pr and ¹³⁹Ce in proton-induced reactions /." Link to the online version, 2007. http://hdl.handle.net/10019/728.

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17

Manuel, Y. Keenoy Maria Begona. "Use of radioisotopes in the study of glucose metabolism: the erythrocyte model." Doctoral thesis, Universite Libre de Bruxelles, 1993. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/212873.

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18

Shaheen, Tahira. "Influence of speciation on the uptake of radioisotopes by zeolite cation exhangers." Thesis, University of Salford, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.315385.

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19

Long, Mark. "Application of radioisotopes to polymer chemistry : investigation of radiolabelled atom transfer polymerization." Thesis, University of Manchester, 2016. https://www.research.manchester.ac.uk/portal/en/theses/application-of-radioisotopes-to-polymer-chemistryinvestigation-of-radiolabelled-atom-transfere-polymerization(deb5aaf4-1bcf-423b-99c2-f9f319f2049a).html.

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The use of the radioisotope 14C in polymer chemistry has been reviewed, showing how it has been used to investigate the mechanistic aspects of free radical polymerizations, and the use of polymers in other scientific disciplines such as environmental, physical, chemical and medical sciences. An overview of the application of fluorescent spectroscopy to polymer chemistry is also reported. It covers the fundamentals of fluorescence chemistry, its application and the potential problems of the use of fluorescent labels in polymer chemistry. The application of radioisotopes to atom transfer radical

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20

Garrido, Eric. "Production de radioisotopes : de la mesure de la section efficace à la production." Phd thesis, Université de Nantes, 2011. http://tel.archives-ouvertes.fr/tel-00662649.

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De nouveaux radio-isotopes pour la médecine nucléaire peuvent être produits par des accélérateurs de particules. C'est l'un des buts d'Arronax, un cyclotron de hautes énergies - 70 MeV - et hautes intensités - 2*350 µA - installé à Nantes. Une liste d'émetteurs b- - 47Sc, 67Cu - b+ - 44Sc, 64Cu, 82Sr/82Rb, 68Ge/68Ga - et a - 211At - à étudier en priorité a été établie. Parmi ceux là, le 47Sc et le 67Cu présentent un intérêt en thérapie ciblée. L'optimisation de leurs productions nécessite la bonne connaissance de leurs sections efficaces, mais aussi de celles de tous les contaminants créés. No

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21

Yoo, Kyung Yeong. "A model for dispersion and deposition of radioisotopes in the planetary boundary layer." Thesis, Queen Mary, University of London, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.283242.

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22

Stokes, Lee [Verfasser], and Tobias [Akademischer Betreuer] Lachenmaier. "Cosmogenic Radioisotopes in the Double Chooz Far Detector / Lee Stokes ; Betreuer: Tobias Lachenmaier." Tübingen : Universitätsbibliothek Tübingen, 2017. http://d-nb.info/1167248015/34.

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23

Stephenson, Karin A. Valliant John Fitzmaurice. "New approaches for the preparation of peptide-targeted radiotracers." *McMaster only, 2005.

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24

Sandell, Johan. "Development of radioligands for the serotonergic neurotransmission system for use in positron emission tomography /." Stockholm, 2001. http://diss.kib.ki.se/2001/91-628-4818-6/.

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25

Ghosh, Sarba Bijoy. "Factors affecting the mobility of selected radionuclides codisposed with municipal refuse within landfills." Thesis, Georgia Institute of Technology, 1987. http://hdl.handle.net/1853/20752.

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26

Shang, Zhaorong. "A study of Ag-110m in aquatic and terrestrial ecosystems and the development of a radioecological model /." Hong Kong : University of Hong Kong, 2001. http://sunzi.lib.hku.hk/hkuto/record.jsp?B23768782.

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27

Moustapha, Moustapha Eid. "A comparative study between no-carrier-added ¹⁸⁶Re, carrier-added ¹⁸⁶Re and no-carrier-added ¹⁸⁸Re for radiolabeling of N₃S-5Ava-BBN(7-14)NH₂ conjugate /." free to MU campus, to others for purchase, 2004. http://wwwlib.umi.com/cr/mo/fullcit?p1422946.

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28

Engle, J. W., T. E. Barnhart, H. F. Valdovinos, S. Graves, P. A. Ellison, and R. J. Nickles. "Making high-value, long-lived isotopes to balance a sustainable radiotracer production facility." Helmholtz-Zentrum Dresden - Rossendorf, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:d120-qucosa-164889.

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Introduction The embrace of PET by medical clinicians has been reluctant (ΔT ≈ 20 yr) primarily due to the scale of the infrastructure that is needed. The capital cost of a cyclotron (≈ 106 USD) is now dwarfed by the demand for compliance to recent regulatory standards. This is a recurring expense, not only imposing an order-of-magnitude increase in staffing and operating costs, but damping the enthusiasm of researchers recalling the brisk pace of research in earlier days. Now an academic site, with little interest or opportunity to scale up production for wider distribution, is burdened by th

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29

Moysey, Stephen. "Meteoric 36-Cl in the Contiguous United States." Thesis, The University of Arizona, 1999. http://etd.library.arizona.edu/etd/GetFileServlet?file=file:///data1/pdf/etd/azu_etd_hy0121_sip1_w.pdf&type=application/pdf.

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30

Adil-Smith, Iran. "Structural analysis of thyroid hormones by EXAFS and molecular simulation : biological effects of '1'2'5I." Thesis, Brunel University, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.362488.

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31

Sridhara, Bangalore Sitaramiah. "Clinical evaluation of '9'9'mTc tetrofosmin in the detection of ischaemic heart disease." Thesis, University of Surrey, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.259561.

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32

Jia, Wei. "The production of high specific activity radionuclides for radiotherapy application /." free to MU campus, to others for purchase, 1996. http://wwwlib.umi.com/cr/mo/fullcit?p9720538.

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33

Dufford, Christopher Allyn. "Feasibility of angular correlation measurements using clinical nuclear medicine equipment." Oklahoma City : [s.n.], 2009.

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34

Xu, Yue. "Electrochemical treatment of metal-bearing aqueous wastes based on novel forms of carbon." Morgantown, W. Va. : [West Virginia University Libraries], 1999. http://etd.wvu.edu/templates/showETD.cfm?recnum=433.

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Thesis (Ph. D.)--West Virginia University, 1999.<br>Title from document title page. Document formatted into pages; contains xv, 207 p. : ill. (some col.) Includes abstract. Includes bibliographical references (p. 203-207).

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35

Davenport, Bradley P. "Advanced thermophotovoltaic cells modeling, optimized for use in rRadioisotope Thermoelectric Generators (RTGS) for Mars and deep space missions /." Monterey, Calif. : Springfield, Va. : Naval Postgraduate School ; Available from National Technical Information Service, 2004. http://library.nps.navy.mil/uhtbin/hyperion/04Jun%5FDavenport.pdf.

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36

Morisset, Natalie Carleton University Dissertation Geology. "Stableisotope and radioisotope geochemistry of the Panda Hill carbonatite, Tanzania." Ottawa, 1992.

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37

Younis, Abdul-Redha Sahib. "Biophysical damage in metallo-enzyme and mammalian cells by Cu-K X-rays and radioisotopes." Thesis, University of St Andrews, 1989. http://hdl.handle.net/10023/14089.

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In the fields of radiobiology and nuclear medicine there is considerable interest in the important role played by Auger electron cascades caused by inner-shell ionisation in realistic risk. It is necessary to quantify this risk when radionuclides are used on a routine basis as investigative, diagnostic and radiotherapeutic tools, whether the applications involve incorporated electron capture radionuclides or K-shell ionisation of selected stable nuclides by X-rays, as in "photon activation therapy". Relevant published survival data on biological damage caused by the internal emitters 125I, 77B

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38

LIMA, CLARICE M. de. "Estudo da marcação e biodistribuição da substância P utilizando lutécio-177 como radiotraçãdor." reponame:Repositório Institucional do IPEN, 2011. http://repositorio.ipen.br:8080/xmlui/handle/123456789/9991.

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39

PERES, ANA C. "Modelo para o estabelecimento de valores orientadores para elementos radioativos no solo." reponame:Repositório Institucional do IPEN, 2007. http://repositorio.ipen.br:8080/xmlui/handle/123456789/11591.

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40

Patel, Amina. "An experimental investigation to assess the feasibility of imaging medical radioisotopes with the ProSPECTus Compton Camera." Thesis, University of Liverpool, 2016. http://livrepository.liverpool.ac.uk/3003463/.

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An experimental investigation into the feasibility of imaging multiple medical radioisotopes with the ProSPECTus Compton camera is presented. The aim of the project is to develop a Compton imaging system configured with segmented solid state detectors, for the purpose of alleviating the limitations of conventional Single Photon Emission Computed Tomography (SPECT) systems. The ProSPECTus system consists of a Si(Li) and HPGe planar detector housed in a magnetic field compatible custom made cryostat. The investigation presented in this thesis has been undertaken with a prototype ProSPECTus syste

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41

Huet-Dales, Aline. "Développement de nouvelles espèces organométalliques pour le marquage par des radioisotopes de courte durée de vie." Bordeaux 1, 2003. http://www.theses.fr/2003BOR12735.

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La réactivité d'organoétains originaux et non polluants a été étudiée lors du couplage de Stille dans des conditions rapides, compatibles avec l'utilisation de radioisotopes de courte durée de vie. Dans un premier temps, les conditions réactionnelles ont été développées afin de transférer un groupement méthyle par couplage de Stille, via la formation du monoorganoétain correspondant. Le temps de réaction a été optimisé sur des modèles, puis les conditions réactionnelles ont été appliquées en chimie du carbone-11. Dans un second temps, la méthodologie mise au point a été utilisée afin de synthé

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42

Speed, Mark. "The isotope hydrology of the River Dee, North East Scotland." Thesis, University of Aberdeen, 2011. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=182254.

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Identifying how the dominant runoff processes of sub-catchments integrate to determine hydrological responses at larger scales (> 1000 km2) remains a major challenge in hydrology. At these larger scales, major environmental differences such as climate, geology and land use may have increased influence on runoff dynamics. While process investigations at smaller scales (< 10km2) have been important in establishing the influence of topography and soils on runoff generation, more research at larger spatial scales is needed, since it is at such scales where important water management decisions are

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43

Livieratos-Petratos, George N. "Neural networks for computer aided diagnosis of pulmonary images in nuclear medicine." Thesis, University of Southampton, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.295017.

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44

Van, Rooy Milton William. "An investigation of a possible effect of reactor antineutrinos on the decay rate of 22Na." Thesis, Stellenbosch : Stellenbosch University, 2015. http://hdl.handle.net/10019.1/97145.

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Thesis (PhD)--Stellenbosch University, 2015.<br>ENGLISH ABSTRACT: Reported claims of a solar neutrino influence on radioactive β - -decay rates prompted a series of three long term measurements that were carried out at the Koeberg nuclear power plant North of Cape Town to investigate the mirror reaction of reactor antineutrinos with a β + - source. The β + -emitter 22Na was exposed to a changing reactor antineutrino flux of the order of ~1012 cm-2 s -1 through the various phases of reactor operation, from off to on or vice versa, to investigate the antineutrino effect on its decay

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45

Adams, B. K. "The role of imaging with iodine-131-meta-iodobenzylguanidine in the diagnosis and localisation of suspected phaeochromocytoma." Thesis, University of Cape Town, 1987. http://hdl.handle.net/11427/25826.

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46

Duringer, Cathy. "La contamination de la thyroide par les radioisotopes de l'iode en cas d'accident nucleaire : methodes de prevention." Université Louis Pasteur (Strasbourg) (1971-2008), 1989. http://www.theses.fr/1989STR1M007.

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47

Dess, Brian William. "Signal processing and pattern recognition methods for the remote, airborne detection of radioisotopes by gamma-ray spectroscopy." Diss., University of Iowa, 2016. https://ir.uiowa.edu/etd/2068.

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The U.S Environmental Protection Agency (USEPA) Airborne Spectral Photometric Environmental Collection Technology (ASPECT) program is designed in part to provide first responders with radiological mapping of potentially hazardous locations. This program utilizes an aircraft fitted with a gamma-ray spectrometer capable of remote detection of radioisotopes. The challenges present in detecting a radioisotope signal remotely are strongly tied to the signal-to-noise ratio of the collected gamma-ray spectra and the specific sign

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48

MADUAR, MARCELO F. "Desenvolvimento de um codigo computacional aberto de analise quantitativa para determinacao de radionuclideos por espectrometria gama com detectores semicondutores." reponame:Repositório Institucional do IPEN, 2010. http://repositorio.ipen.br:8080/xmlui/handle/123456789/9534.

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49

Leigh, Sasha Naomi Bharier. "A study of the dynamics of the British Ice Sheet during Marine Isotope Stages 2 and 3, focusing on Heinrich Events 2 and 4 and their relationship to the North Atlantic glaciological and climatological conditions /." St Andrews, 2007. http://hdl.handle.net/10023/525.

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50

Shang, Zhaorong, and 商照榮. "A study of Ag-110m in aquatic and terrestrial ecosystems and the development of a radioecological model." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2001. http://hub.hku.hk/bib/B29747326.

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