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Journal articles on the topic 'Radioisotopes'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Kilian, Krzysztof, and Krystyna Pyrzyńska. "Scandium Radioisotopes—Toward New Targets and Imaging Modalities." Molecules 28, no. 22 (2023): 7668. http://dx.doi.org/10.3390/molecules28227668.

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The concept of theranostics uses radioisotopes of the same or chemically similar elements to label biological ligands in a way that allows the use of diagnostic and therapeutic radiation for a combined diagnosis and treatment regimen. For scandium, radioisotopes -43 and -44 can be used as diagnostic markers, while radioisotope scandium-47 can be used in the same configuration for targeted therapy. This work presents the latest achievements in the production and processing of radioisotopes and briefly characterizes solutions aimed at increasing the availability of these radioisotopes for resear

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2

Motahari, Sayed Mahdi, and Fatemah Alemzada. "Radiopharmaceuticals: Production, Physics, and Clinical Applications in Nuclear Medicine: A Short Review." Afghanistan Journal of Basic Medical Science 2, no. 2 (2024): 43–52. http://dx.doi.org/10.62134/ajbms/v2.i2.khatamuni.6.

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Introduction: The use of radioactive atoms in medicine is growing, particularly in nuclear medicine, where radiation is emitted from the body. Radiopharmaceuticals or radiotracers are artificial short-living radioisotopes labeled with special pharmaceuticals. There are around 1800 radioisotopes, but only around 200 are suitable for general applications. There are four methods for generating radioisotopes: reactor-producing, neutron activation, charged acceleration, and radioisotope generators. Cyclotrons are used to produce many other radioisotopes for medical applications. Physical and biomed

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3

Pimlott, Sally L. "Radioisotopes for medical imaging." International Journal of Modern Physics A 29, no. 14 (2014): 1441003. http://dx.doi.org/10.1142/s0217751x14410036.

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4

Nunes, Bruno Silveira, Enio Rodrigo Fernandes Rodrigues, Jonathan Alexander Prestes Fruscalso, Roger Pizzato Nunes, Alexandre Bonatto, and Mirko Salomón Alva-Sánchez. "Highly Enriched Uranium-Free Medical Radioisotope Production Methods: An Integrative Review." Applied Sciences 12, no. 24 (2022): 12569. http://dx.doi.org/10.3390/app122412569.

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The ever-growing need for radiopharmaceuticals, i.e., compounds containing pharmaceutical drugs and radioisotopes used for medical diagnostic imaging (SPECT/PET scan) and treating neoplasms, is significantly leading to an increased demand for such substances in hospitals and clinics worldwide. Currently, most large-scale productions of radioisotopes required for radiopharmaceuticals are carried out in research reactors, via the fission of highly enriched uranium. However, because large amounts of radioactive waste are produced as byproducts in this process, new greener methods are needed for r

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Perini, Efrain Araujo, Mikhail Skopchenko, Tran Thu Hong, et al. "Pre-feasibility Study for Establishing Radioisotope and Radiopharmaceutical Production Facilities in Developing Countries." Current Radiopharmaceuticals 12, no. 3 (2019): 187–200. http://dx.doi.org/10.2174/1874471012666190328164253.

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Background:A significant number of developing countries have no facilities to produce medical radioisotopes and radiopharmaceuticals.Objective:In this paper we show that access to life-saving radioisotopes and radiopharmaceuticals and the geographical distribution of corresponding infrastructure is highly unbalanced worldwide.Methods:We discuss the main issues which need to be addressed in order to establish the production of radioisotopes and radiopharmaceuticals, which are especially important for developing countries as newcomers in the field. The data was gathered from several sources, inc

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Noori-Asl, Mahsa, and Maryam Eghbal. "Comparing the Performance of Scatter Correction Methods in Cardiac SPECT Imaging with Technetium-99m and Thallium-201 Radioisotopes." Journal of Medical Physics 49, no. 3 (2024): 464–72. http://dx.doi.org/10.4103/jmp.jmp_40_24.

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Purpose: This study aims to evaluate the performance of dual-energy window (DEW) and triple-energy window (TEW) scatter correction methods in cardiac SPECT imaging with technetium-99m (Tc-99m) and thallium-201 (Tl-201) radioisotopes. Materials and Methods: The SIMIND Monte Carlo program was used to simulate the imaging system and produce the required projections. Two phantoms, including the simple cardiac phantom and the NCAT phantom, were used to evaluate the scatter correction methods. The simulations were repeated 5 times for each phantom and finally, the mean values obtained from these 5 t

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Konefał, Adam, Andrzej Orlef, and Maria Sokół. "Application of therapeutic linear accelerators for the production of radioisotopes used in nuclear medicine." Polish Journal of Medical Physics and Engineering 28, no. 3 (2022): 107–16. http://dx.doi.org/10.2478/pjmpe-2022-0013.

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Abstract This review paper summarizes the possibilities of the use of therapeutic linear electron accelerators for the production of radioisotopes for nuclear medicine. This work is based on our published results and the thematically similar papers by other authors, directly related to five medical radioisotopes as 99Mo/99mTc, 198Au, 186Re, 188Re, 117mSn, produced using therapeutic linacs. Our unpublished data relating to the issues discussed have also been used here. In the experiments, two types of radiation were included in the analysis of the radioisotope production process, i.e. the thera

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Kambali, Imam, Indra Saptiama, and Hari Suryanto. "Residual Radioisotopes Generated from Neutron Irradiated Aluminum Capsules." Aceh International Journal of Science and Technology 6, no. 3 (2017): 104–10. http://dx.doi.org/10.13170/aijst.6.3.8116.

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Aluminum (Al) is often used to house a molybdenum oxide (MoO3) target for neutron or proton-produced technetium-99m (99mTc) radioisotope. During neutron or proton bombardment of an Al body, residual radioisotopes could be generated following nuclear reactions between the incoming particles and the Al body. In this research, residual radioisotopes produced following nuclear reactor based-neutron irradiation of Al body were experimentally measured using a portable gamma ray spectroscopy system; whereas TALYS 2015 calculated data were used to evaluate various nuclear reactions for the by-product

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9

Lapi, Suzanne E., and Jonathan W. Engle. "Radiochlorine: an underutilized halogen tool." Radiochimica Acta 107, no. 9-11 (2019): 1027–31. http://dx.doi.org/10.1515/ract-2019-0015.

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Abstract Halogen radioisotopes have a variety of physical half-lives which are suitable for probing a wide variety of pharmacokinetic processes. Compared with other radiohalogens, relatively little work has been done with radiochlorine. However, high specific activity radioisotopes of chlorine are available from low energy cyclotron production in quantities suitable for positron emission tomography (PET) and fundamental research. In particular, the sole radioisotope of chlorine which may be used for PET imaging, 34mCl, has achieved a state of development that permits imaging in clinical settin

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Pellico, Juan, Jordi Llop, Irene Fernández-Barahona, Riju Bhavesh, Jesús Ruiz-Cabello, and Fernando Herranz. "Iron Oxide Nanoradiomaterials: Combining Nanoscale Properties with Radioisotopes for Enhanced Molecular Imaging." Contrast Media & Molecular Imaging 2017 (2017): 1–24. http://dx.doi.org/10.1155/2017/1549580.

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The combination of the size-dependent properties of nanomaterials with radioisotopes is emerging as a novel tool for molecular imaging. There are numerous examples already showing how the controlled synthesis of nanoparticles and the incorporation of a radioisotope in the nanostructure offer new features beyond the simple addition of different components. Among the different nanomaterials, iron oxide-based nanoparticles are the most used in imaging because of their versatility. In this review, we will study the different radioisotopes for biomedical imaging, how to incorporate them within the

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11

Usman, Ahmed Rufai, and Ibrahim Abdullahi Lawal. "PROGRESS IN NICKEL TARGET DESIGNS FOR DEUTERON IRRADIATION: A MILESTONE IN RADIOISOTOPE PRODUCTION OPTIMIZATION." FUDMA JOURNAL OF SCIENCES 6, no. 5 (2022): 211–14. http://dx.doi.org/10.33003/fjs-2022-0605-1484.

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Medical radioisotopes play significant roles in nuclear medicine, particularly in tumor diagnosis and its therapy. Optimization in production of these important isotopes is very essential for the overall health of the target patients. In this work, we analyzed general trends in the use of various forms of nickel metal as target for radioisotopes production in nuclear accelerators. A careful study of all previously used forms of nickel metal in the literature up to 2016 indicate that different physical forms of the metal, such as its very high purity and impure forms, alloys, compounds and powd

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Usman, Ahmed Rufai, and Ibrahim Abdullahi Lawal. "PROGRESS IN NICKEL TARGET DESIGNS FOR DEUTERON IRRADIATION: A MILESTONE IN RADIOISOTOPE PRODUCTION OPTIMIZATION." FUDMA JOURNAL OF SCIENCES 7, no. 2 (2023): 121–24. http://dx.doi.org/10.33003/fjs-2023-0702-1718.

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Medical radioisotopes play significant roles in nuclear medicine, particularly in tumor diagnosis and its therapy. Optimization in production of these important isotopes is very essential for the overall health of the target patients. In this work, we analyzed general trends in the use of various forms of nickel metal as target for radioisotopes production in nuclear accelerators. A careful study of all previously used forms of nickel metal in the literature up to 2016 indicate that different physical forms of the metal, such as its very high purity and impure forms, alloys, compounds and powd

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13

Abdur Rahim. "Quality Control Procedure of Clinical Nuclear Medicine Instruments and Comparisons with Standard Protocol (At DINAR Cancer Hospital D. I. Khan)." Tuijin Jishu/Journal of Propulsion Technology 45, no. 04 (2024): 1126–38. http://dx.doi.org/10.52783/tjjpt.v45.i04.8353.

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Quality control of clinical Nuclear medicine instruments” i.e. used, used in this research work i.e. radioisotope dose calibrator and SPECT gamma camera is most important for reliable operational characteristics in this research work different tests has been done taking data from “ GE- Infinia Hawkeye” SPECT Gamma camera at “DINAR” Cancer hospital D.I.Khan.Auto zero, background, linearity, geometry, constancy and accuracy tests were performed in the case of radioisotopes dose calibrator while tests performed in case of SPECT gamma camera includes background, energy peak, C.O.R and uniformity t

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Abdur Rahim. "Quality Control Procedure of Clinical Nuclear Medicine Instruments and Comparisons with Standard Protocol (At DINAR Cancer Hospital D. I. Khan)." Tuijin Jishu/Journal of Propulsion Technology 45, no. 04 (2024): 1126–38. http://dx.doi.org/10.52783/tjjpt.v45.i04.8270.

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Quality control of clinical Nuclear medicine instruments” i.e. used, used in this research work i.e. radioisotope dose calibrator and SPECT gamma camera is most important for reliable operational characteristics in this research work different tests has been done taking data from “ GE- Infinia Hawkeye” SPECT Gamma camera at “DINAR” Cancer hospital D.I.Khan.Auto zero, background, linearity, geometry, constancy and accuracy tests were performed in the case of radioisotopes dose calibrator while tests performed in case of SPECT gamma camera includes background, energy peak, C.O.R and uniformity t

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15

Acosta, Luis, Paulina Amador-Valenzuela, Eduardo Andrade, et al. "The AMS technique as an important tool for the measurement of astrophysical cross sections." EPJ Web of Conferences 252 (2021): 05003. http://dx.doi.org/10.1051/epjconf/202125205003.

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Accelerator Mass Spectrometry is a technique commonly used to approach low concentrations of certain long half-life radioisotopes. The most important contribution of the technique is the accurate measure of organic sample ages, by separating masses 12,13 and 14 in the case of carbon allocated in such samples. However, the reach of AMS could cover many other scientiﬁc scopes, since it can give us a precise measure of a very small concentration of a radioisotope. On this direction, AMS can be used to approach reactions of interest for astrophysics, if we spot an specific radioisotope which conce

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16

LaBrecque, J. J., and P. A. Rosales. "The Application of P-32 and Sn-113 Radionuclides for the Determination of Noble Metals." Advances in X-ray Analysis 32 (1988): 255–59. http://dx.doi.org/10.1154/s0376030800020553.

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Recently, a new radioisotope X-ray fluorescence technique was reported in which a small quantity (100μCi) of a selected radioisotope was directly mixed with a small amount of the sample, as a source-sample. Many different types of excitation radiation from various radioisotopes have been previously studied: Na-22, S-35, Fe-55, Co-57, Hi-63, Zn-65, Cd-109, 1-125, Cs-137, Pa-147 and Ara-241.

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17

KARPUZ DEMİR, Nurdan. "Investigation of the Cross Sections and Effect of Level Density Models for Platinum Element." Afyon Kocatepe University Journal of Sciences and Engineering 22, no. 6 (2022): 1256–70. http://dx.doi.org/10.35414/akufemubid.1143137.

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In cases where experimental studies cannot be carried out and there is no experimental data with it, studies carried out with theoretical models shed light on the researchers' knowledge of different data. The most important of this data is the measurable or calculatable influence cross-section value, which is defined as the probability of a reaction occurrence. Examining the possible effects of different models in the calculation of the effect section is important for the correct calculation of this value. The most important data, the cross section of influence, has taken its place in the radi

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18

Khan, Hamda, Umair Aziz, and Zafar Ullah Koreshi. "Radiation dose delivered by 125I, 103Pd and 131Cs and dose enhancement by gold nanoparticle (GNP) solution in prostate brachytherapy: a comparative analysis by Monte Carlo simulation." IIUM Engineering Journal 20, no. 2 (2019): 176–87. http://dx.doi.org/10.31436/iiumej.v20i2.1136.

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: The energy deposition and radiation dose from commonly used radioisotopes, 125I,103Pd, and 131Cs, used for brachytherapy of cancers is estimated using Monte Carlo (MC) simulations. To enhance the dose, gold nanoparticle (GNP) solutions are injected into the tumor; this results in more effective and shorter therapy duration. It is thus important to estimate the dose enhancement factor (DEF) achievable by a radioisotope. The research presented in this paper thus focuses on a comparative analysis of radioisotopes. To estimate the radiation dose, the Monte Carlo N-particle code MCNP5 was used fo

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Setiawan, Duyeh, and Titin Sri Mulyati. "PEMBUATAN DAN ANALISIS FISIKO-KIMIA RADIOISOTOP SKANDIUM-47 (47Sc) DARI BAHAN SASARAN TITANIUM OKSIDA ALAM." Jurnal Sains dan Teknologi Nuklir Indonesia 16, no. 2 (2015): 63. http://dx.doi.org/10.17146/jstni.2015.16.2.2379.

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Radioisotop skandium-47 (47Sc) memiliki waktu paruh 3,35 hari, pemancar energi beta, Eβmax 0,441 MeV (68 %) dan 0,601 MeV (32 %), serta pemancar energi gamma, Eγ 159 keV (68 %). Radioisotop 47Sc dihasilkan oleh iradiasi neutron cepat dari target titanium berdasarkan reaksi inti 47Ti (n, p) 47Sc. Metode pemisahan 47Sc menggunakan cara kromatografi kolom dengan matriks Dowex AG 50W-x4 dalam bentuk kation (H+), selanjutnya 47Sc dielusi dengan HCl 4 M. Radioisotop 47Sc digunakan dalam bidang kedokteran nuklir untuk radioterapi dengan metode pencitraan. Karakteristik fisiko-kimia suatu sediaan radi

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Martini, Petra, Andrea Adamo, Neilesh Syna, et al. "Perspectives on the Use of Liquid Extraction for Radioisotope Purification." Molecules 24, no. 2 (2019): 334. http://dx.doi.org/10.3390/molecules24020334.

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The reliable and efficient production of radioisotopes for diagnosis and therapy is becoming an increasingly important capability, due to their demonstrated utility in Nuclear Medicine applications. Starting from the first processes involving the separation of 99mTc from irradiated materials, several methods and concepts have been developed to selectively extract the radioisotopes of interest. Even though the initial methods were based on liquid-liquid extraction (LLE) approaches, the perceived difficulty in automating such processes has slowly moved the focus towards resin separation methods,

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Duong, Van Dong, Ngoc Dien Pham, Van Cuong Bui, Phuoc Tho Mai, Thi Thu Nguyen, and Cam Hoa Vo Thi. "Production of Radioisotopes and Radiopharmaceuticals at the Dalat Nuclear Research Reactor." Nuclear Science and Technology 4, no. 1 (2014): 46–56. http://dx.doi.org/10.53747/jnst.v4i1.213.

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After reconstruction, the Dalat Nuclear Research Reactor (DNRR) was inaugurated on March 20th, 1984 with the nominal power of 500 kW. Since then the production of radioisotopes and labelled compounds for medical use was started. Up to now, DNRR is still the unique one in Vietnam. The reactor has been operated safely and effectively with the total of about 37,800 hrs (approximately 1,300 hours per year). More than 90% of its operation time and over 80% of its irradiation capacity have been exploited for research and production of radioisotopes. This paper gives an outline of the radioisotope pr

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22

Islam, Md Rafiqul, Mehrdad Shahmohammadi Beni, Shigeki Ito, Shinichi Gotoh, Taiga Yamaya, and Hiroshi Watabe. "An Analysis Scheme for 3D Visualization of Positron Emitting Radioisotopes Using Positron Emission Mammography System." Applied Sciences 12, no. 2 (2022): 823. http://dx.doi.org/10.3390/app12020823.

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Proton range monitoring and verification is important to enhance the effectiveness of treatment by ensuring that the correct dose is delivered to the correct location. Upon proton irradiation, different positron emitting radioisotopes are produced by the inelastic nuclear interactions of protons with the target elements. Recently, it was reported that the 16O(p,2p2n)13N reaction has a relatively low threshold energy, and it could be potentially used for proton range verification. In the present work, we have proposed an analysis scheme (i.e., algorithm) for the extraction and three-dimensional

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Molo, Yosefina, Bartholomeus Pasangka, and Jehunias Leonidas Tanesib. "INVESTIGASI KANDUNGAN RADIOISOTOP DALAM SAMPEL BATUAN DI MUARA SUNGAI SUMLILI KUPANG BARAT." Jurnal Fisika : Fisika Sains dan Aplikasinya 5, no. 1 (2020): 11–18. http://dx.doi.org/10.35508/fisa.v5i1.1235.

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Abstrak Masalah pokok yang dikaji di penelitian ini adalah pemetaan dan analisis aktivitas jenis kandungan radioisotop dalam sampel batuan di muara sungai Sumlili Kupang Barat. Tujuan penelitian meliputi : menentukanrange cacah dan aktivitas jenis massa (C) kandungan radioisotop dalam sampel pasir di muara sungai Sumlili Kupang Barat, mengestimasi tingkat kontaminasi radioisotop sesuai standar di sekitar muara sungai Sumlili, dan memetakan sebaran cacah radioisotop pada luasan daerah tertentu yang terjangkau survei di lapangan. Metode penelitian meliputi : observasi/survei, sampling, ser

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Vretenar, M., A. Mamaras, G. Bisoffi, and P. Foka. "Production of radioisotopes for cancer imaging and treatment with compact linear accelerators." Journal of Physics: Conference Series 2420, no. 1 (2023): 012104. http://dx.doi.org/10.1088/1742-6596/2420/1/012104.

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Abstract Accelerator-produced radioisotopes are widely used in modern medicine, for imaging, for cancer therapy, and for combinations of therapy and diagnostics (theragnostics). Clinical trials are well advanced for several radioisotope-based treatments that might open the way to a strong request of specific accelerator systems dedicated to radioisotope production. While cyclotrons are the standard tool in this domain, we explore here alternative options using linear accelerators. Compared to cyclotrons, linacs have the advantage of modularity, compactness, and reduced beam loss with lower shi

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SCHUBERT, H., R. LEONTE, S. BĂRUȚĂ, F. NEGOIȚĂ, and D. NICULAE. "Production of medical radioisotopes via photonuclear reactions: review of candidates and opportunities for the planned radioactive ion facility at IFIN-HH." Romanian Reports in Physics 76, no. 2 (2024): 203. http://dx.doi.org/10.59277/romrepphys.2024.76.203.

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Radioisotopes have a growing impact in various fields of industry and medicine. Especially in modern medicine, based on the synergies of nuclear physics, radiochemistry, and radiobiology, the demand for more readily available, higher quality, and also new radioisotopes is constantly increasing. As key components of radiopharmaceuticals, they are used in many ways for diagnostics imaging, and treatments of cancer or other health issues. Diagnostics based on the precise positioning of imaging photons have improved due to recent advances in molecular biology. Ongoing intense research of biologica

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Izzotti, A., A. Pulliero, Z. Khalid, et al. "Using Natural Isotopes for the Environmental Tracking of a Controlled Landfill Site for Non-Hazardous Waste in Liguria, Italy." International Journal of Environmental Research and Public Health 22, no. 4 (2025): 528. https://doi.org/10.3390/ijerph22040528.

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The application of natural radioisotope and stable isotope tracing represents a novel, sensitive method for confirming the presence of environmental contamination due to leachate water from solid waste landfills. This study aimed to employ this approach to assess the efficiency of containment measures and the potential environmental impact in the vicinity of a landfill designated for non-hazardous waste disposal. We collected leachate water samples from two distinct areas: one currently active, and another exhausted. In February, May, August, and November 2022, we collected deep water samples

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Entry, James A., and William H. Emmingham. "Sequestration of 137Cs and 90Sr from soil by seedlings of Eucalyptustereticotnis." Canadian Journal of Forest Research 25, no. 6 (1995): 1044–47. http://dx.doi.org/10.1139/x95-114.

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The ability of seedlings of Eucalyptustereticornis Smith to accumulate 137Cs and 90Sr, characteristic radioisotopes of nuclear fallout, from contaminated growth medium was tested. All seedlings were grown for 3 months in 165 cm3 of sphagnum peat moss–perlite (1:1 v/v) in a growth chamber before treatment with an isotope. After 1 month of exposure, seedlings had accumulated 31.0% of the 137Cs and 11.3% of the 90Sr originally present in the growth medium, with bioconcentration ratios of 54:1 for 137Cs and 13:1 for 90Sr. Accumulation of 137Cs and 90Sr in plant tissue was correlated curvilinearly

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Jeon, Byoungil, Jongyul Kim, Yonggyun Yu, and Myungkook Moon. "Comparison of Machine Learning-Based Radioisotope Identifiers for Plastic Scintillation Detector." Journal of Radiation Protection and Research 46, no. 4 (2021): 204–12. http://dx.doi.org/10.14407/jrpr.2021.00206.

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Background: Identification of radioisotopes for plastic scintillation detectors is challenging because their spectra have poor energy resolutions and lack photo peaks. To overcome this weakness, many researchers have conducted radioisotope identification studies using machine learning algorithms; however, the effect of data normalization on radioisotope identification has not been addressed yet. Furthermore, studies on machine learning-based radioisotope identifiers for plastic scintillation detectors are limited.Materials and Methods: In this study, machine learning-based radioisotope identif

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Rabbani, AFM Masum, Md Shohag Mia, Hasan Mehdi, et al. "Optimization of 18F Radioisotope Production with Cyclone 18/9 MeV IBA Cyclotron Installed at NINMAS." Dhaka University Journal of Science 71, no. 1 (2023): 56–59. http://dx.doi.org/10.3329/dujs.v71i1.65273.

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A cyclotron is a particle accelerator, which employs electromagnetic fields to accelerate charged particles to extremely high speeds and energy. It is used to create radioisotopes for radiopharmaceuticals, which are used to diagnose and treat cancer. Because cyclotron-produced radiopharmaceuticals are exceptionally effective in identifying various cancers. Cyclotrons are fast evolving and will play an increasingly important role in the healthcare industry, particularly in advanced medical imaging techniques like positron emission tomography-computed tomography (PET-CT) and single photon emissi

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Inacio, Pascoleta, Albert Zicko Johannes, and Bartholomeus Pasangka. "INVESTIGASI KANDUNGAN RADIOISOTOP DALAM SAMPEL SUMBER MATA AIR DI DESA LALETEN KECAMATAN WELIMAN KABUPATEN MALAKA." Jurnal Fisika : Fisika Sains dan Aplikasinya 3, no. 2 (2018): 106–9. http://dx.doi.org/10.35508/fisa.v3i2.610.

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Abstrak Telah dilakukan penelitian untuk memeriksa kandungan radioisotop dalam sampel sumber mata air di Desa Laleten Kecamatan Weliman Kabupaten Malaka. Penelitian ini bertujuan untuk menentukan interval dan tingkat aktivitas jenis massa kandungan radioisotop dari sumber air minum lokal dan kemudian dibandingkan dengan standar untuk tingkat kontaminasi dan standar ambang batas dosis radiasi yang diperbolehkan untuk persyaratan air minum (Permenkes RI). Metode yang digunakan dalam penelitian ini yaitu dengan metode sampling. Sampel dari lapanga dipanaskan dan dikeringkan di laboratorium

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Oddy, JM. "Radioisotopes." Biochemical Education 21, no. 2 (1993): 114. http://dx.doi.org/10.1016/0307-4412(93)90078-e.

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Kauffman, Nathan, James Morrison, Kevin O’Brien, Jinda Fan, and Kurt R. Zinn. "Intra-Arterial Delivery of Radiopharmaceuticals in Oncology: Current Trends and the Future of Alpha-Particle Therapeutics." Pharmaceutics 15, no. 4 (2023): 1138. http://dx.doi.org/10.3390/pharmaceutics15041138.

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A paradigm shift is underway in cancer diagnosis and therapy using radioactivity-based agents called radiopharmaceuticals. In the new strategy, diagnostic imaging measures the tumor uptake of radioactive agent “X” in a patient’s specific cancer, and if uptake metrics are realized, the patient can be selected for therapy with radioactive agent “Y”. The X and Y represent different radioisotopes that are optimized for each application. X–Y pairs are known as radiotheranostics, with the currently approved route of therapy being intravenous administration. The field is now evaluating the potential

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Jha, Ashish Kumar. "Advancing Nuclear Medicine through Discovery, Invention, and Innovation – Contribution of a Physicist and Scientist (Vikram Sarabhai Memorial Oration-2023)." Indian Journal of Nuclear Medicine 39, no. 6 (2024): 421–27. https://doi.org/10.4103/ijnm.ijnm_118_24.

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The history of radiation science began with Wilhelm Rontgen’s discovery of X-rays in 1895, followed closely by Henri Becquerel’s discovery of radioactivity in 1896. Subsequent research focused on developing radioisotope technology and exploring its applications in medical diagnosis and treatment. The first recorded use of radioisotopes for tumor treatment was by William Dune in Marie Curie’s laboratory. George D Heawse employed radioisotopes to study plant and animal physiology. Irene and Joliot Curie pioneered the production of artificial radioisotopes using alpha particle bombardment. Ernest

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Suhartini, Nita, Barokah Aliyanta, and Arief Adhari. "PLANTS COVERING INFLUENCE TO THE RADIOISOTOPES EXISTENCE OF Cs-137 AND Pb-210 IN THE SOIL." Jurnal Forum Nuklir 14, no. 1 (2020): 7. http://dx.doi.org/10.17146/jfn.2020.14.1.5811.

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PLANTS COVERING INFLUENCE TO THE RADIOISOTOPES EXISTENCE OF 137Cs and 210Pbex IN THE SOIL. Cs-137 and Pbex-210 of environmental radioisotope content in the soil can be useful to estimate the rate of erosion/deposition in an area, by comparing the inventory value of Cs-137 or Pbex-210 in observed site with those in a stable reference site. Cs-137 and Pbex-210 stick very strongly at the surface of the soil (clay), so it can use as a tracer for the movement of soil. Plants very influence the existence of Cs-137 and Pbex-210 environmental radioisotopes as a cover. If without a plant cover, then th

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Birchler, Justin, Courtney Harris, Christopher Sherwood, and Tara Kniskern. "Sediment Transport Model Including Short-Lived Radioisotopes: Model Description and Idealized Test Cases." Journal of Marine Science and Engineering 6, no. 4 (2018): 144. http://dx.doi.org/10.3390/jmse6040144.

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Geochronologies derived from sediment cores in coastal locations are often used to infer event bed characteristics such as deposit thicknesses and accumulation rates. Such studies commonly use naturally occurring, short-lived radioisotopes, such as Beryllium-7 (7Be) and Thorium-234 (234Th), to study depositional and post-depositional processes. These radioisotope activities, however, are not generally represented in sediment transport models that characterize coastal flood and storm deposition with grain size patterns and deposit thicknesses. We modified the Community Sediment Transport Modeli

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GORBACHENKO, Oleksandr, and Volodymyr PLUJKO. "ANALYSIS OF AMBIGUITIES IN THE DETERMINATION OF CROSS SECTIONS OF THE RADIOISOTOPES 99mTc, 177Lu FORMATION." Medical physics – the current status, problems, the way of development. Innovation technologies, no. 1 (2024): 304–12. https://doi.org/10.17721/3041-1491/2024.11-40.

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Experimental data on cross-section values of the formation of medical radioisotopes 99mTc, 177Lu in photonuclear reactions are compared with evaluated data and calculations made taking into account uncertainties in the characteristics of excited states of atomic nuclei. The experimental data from the EXFOR database are given with sufficiently large uncertainties, and modern evaluated data from the TENDL2023 data library at many energies do not agree with the experimental data. Therefore, in order to reliably determine the corresponding photoabsorption cross-sections that determine the producti

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Braccini, Saverio, and Francisco Alves. "Special Issue ”Instruments and Methods for Cyclotron Produced Radioisotopes”." Instruments 3, no. 4 (2019): 60. http://dx.doi.org/10.3390/instruments3040060.

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The 17th Workshop on Targets and Target Chemistry (WTTC17) was held in Coimbra (Portugal) on 27–31 August 2018. A few months before, the 13th Workshop of the European Cyclotron Network (CYCLEUR) took place in Lisbon (Portugal) on 23–24 November 2017. These two events reassembled major experts in the field of radioisotope production, targets, target chemistry and cyclotrons. In the last few years, significant advances have been obtained in these fields with direct implications for science and society. Instruments and methods, originally developed for nuclear and particle physics, played a cruci

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Lima, Carla Flávia de, and Tarcisio Passos Ribeiro de Campo. "Dosimetric evaluation in radiation synovectomy." Brazilian Archives of Biology and Technology 48, spe2 (2005): 153–58. http://dx.doi.org/10.1590/s1516-89132005000700022.

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Rheumatoid arthritis can manifest itself through synovitis, of which the knee is the common locale. The treatment using an intra-articular radioisotope injection has been applied in various countries. In this work, the dose of radioactive material absorbed in the joint is evaluated, taking into consideration the dose received in the articular cartilage and adjacencies using a three-dimensional voxel model representing the knee. The radioisotopes studied were Samarium-153 and Dysprosium-165. The results show that the synovial membrane receives 85 to 98% of the normalized dose taken from all vox

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Hirsch, Ariel E. "Polymethylmethacrylate and Radioisotopes in Vertebral Augmentation: An Explanation of Underlying Principles." September 2009 5;12, no. 5;9 (2009): 887–91. http://dx.doi.org/10.36076/ppj.2009/12/887.

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We recently reported a novel concept for combining radioactive isotope technology with polymethylmethacrylate (PMMA) cement used for vertebral augmentation and have advocated that pain physicians become aware of this new concept when treating malignant compression fractures. The use of vertebral augmentation for malignant compression fractures is steadily increasing, and the goal of this novel approach would be to stabilize the fractured vertebral body while also controlling proliferation of the tumor cells in the vertebral body that caused the vertebral fracture. This approach would therefore

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Lim, Su Wei, Constantina Chrysochou, David L. Buckley, Philip A. Kalra, and Steven P. Sourbron. "Prediction and assessment of responses to renal artery revascularization with dynamic contrast-enhanced magnetic resonance imaging: a pilot study." American Journal of Physiology-Renal Physiology 305, no. 5 (2013): F672—F678. http://dx.doi.org/10.1152/ajprenal.00007.2013.

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The aim of this study was to assess the potential of dynamic contrast-enhanced (DCE) MRI to predict and evaluate functional outcomes after renal artery revascularization for renal artery stenosis (RAS). The single-kidney glomerular filtration rate (SK-GFR) was measured in 15 patients with atherosclerotic RAS with DCE-MRI and radioisotopes at baseline and 4 mo after revascularization. DCE-MRI also produced measurements of blood flow, blood volume, extraction fraction, tubular transit time, and functional volume. Stented kidneys ( n = 22) were divided into three response groups on the basis of t

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KINOSHITA, Fumio. "Application of Radioisotopes to Therapies. I. Overview of radioisotope internal therapy." RADIOISOTOPES 43, no. 8 (1994): 491–502. http://dx.doi.org/10.3769/radioisotopes.43.8_491.

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TANAKA, Eiichi. "Diagnostic imaging by radioisotopes. Basic. IV. Imaging apparatus for radioisotope tomographic diagnosis." RADIOISOTOPES 34, no. 1 (1985): 57–66. http://dx.doi.org/10.3769/radioisotopes.34.57.

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Salvanou, Evangelia-Alexandra, Argiris Kolokithas-Ntoukas, Christos Liolios, et al. "Preliminary Evaluation of Iron Oxide Nanoparticles Radiolabeled with 68Ga and 177Lu as Potential Theranostic Agents." Nanomaterials 12, no. 14 (2022): 2490. http://dx.doi.org/10.3390/nano12142490.

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Theranostic radioisotope pairs such as Gallium-68 (68Ga) for Positron Emission Tomography (PET) and Lutetium-177 (177Lu) for radioisotopic therapy, in conjunction with nanoparticles (NPs), are an emerging field in the treatment of cancer. The present work aims to demonstrate the ability of condensed colloidal nanocrystal clusters (co-CNCs) comprised of iron oxide nanoparticles, coated with alginic acid (MA) and stabilized by a layer of polyethylene glycol (MAPEG) to be directly radiolabeled with 68Ga and its therapeutic analog 177Lu. 68Ga/177Lu- MA and MAPEG were investigated for their in vitr

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Usman, Rilwan Loko, Umar Ibrahim, Samson Dauda Yusuf, Idris Muhammad Mustapha, Emmanuel Ifeanyi Ugwu, and Olatunji Samuel Ayanninuola. "Identification of Medical and Industrial Used Radioisotopes in Mining Sites of Nasarawa, Nasarawa State, Nigeria." Journal of Oncology Research 4, no. 1 (2022): 27. http://dx.doi.org/10.30564/jor.v4i1.3635.

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This research intends to unveil the presence of radioisotopes in the soil of some mining sites in Nasarawa of Nasarawa state using thermos-scientific interceptor (IdentiFINDER). The work aimed at detecting the presence, types and trust level of radioisotopes. The result showed that, 103Pd and 125I were found in 57% of the total points and the percentage abundance of the detector reached 50-65% indicating that, those radioisotopes are likely found in the area, 109Cd was found in 15% of the total areas. The percentage abundance of the detector for 109Cd shows 50% indicating that, those radioisot

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YAMASHITA, Takashi, and Yoshio ONAI. "Application of Radioisotopes to Therapies. II. Overview of radioisotope external radiotherapy and brachytherapy." RADIOISOTOPES 43, no. 9 (1994): 565–74. http://dx.doi.org/10.3769/radioisotopes.43.9_565.

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Forseth, Torbjørn, Bror Jonsson, Roger Næumann, and Ola Ugedal. "Radioisotope Method for Estimating Food Consumption by Brown Trout (Salmo trutta)." Canadian Journal of Fisheries and Aquatic Sciences 49, no. 7 (1992): 1328–35. http://dx.doi.org/10.1139/f92-148.

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A fast, simple, and reliable method for estimating food consumption using radioisotopes is presented. The method gives both sensitive short-term and robust long-term estimates of food consumption for brown trout (Salmo trutta). The estimates of daily food rations were similar to those estimated from rates of gastric evacuation and laboratory experiments. The radioisotope method can be used to detect variations in ration size due to temperature, fish size, and food availability. Information on radiocesium absorption from this study and earlier published data on radiocesium retention can be used

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Pourjafar, Mansoureh. "Radioisotopes in Agricultural Industry." IRA-International Journal of Technology & Engineering (ISSN 2455-4480) 8, no. 3 (2017): 39. http://dx.doi.org/10.21013/jte.v8.n3.p1.

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<p>In environment there are approximately 300 nuclei, containing of different components and their isotopes. Isotopes are nuclei having the similar number of protons and different number of neutrons. Radioisotopes can be applied in vast range of agricultural systems. Scientists are solving the mysteries of multitude agricultural difficulties, which could not have been conceivable with formal ways. Radioisotopes were used in many range of application such as killing insects which damage the food grains by radiations, determining the function of fertilizers in different plants and increase

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Alamaniotis, Miltiadis, Chan K. Choi, and Lefteri H. Tsoukalas. "Application of Fireworks Algorithm in Gamma-Ray Spectrum Fitting for Radioisotope Identification." International Journal of Swarm Intelligence Research 6, no. 2 (2015): 102–25. http://dx.doi.org/10.4018/ijsir.2015040105.

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Identification of radioisotopic signature patterns in gamma-ray spectra is of paramount importance in various applications of gamma spectroscopy. Therefore, there are several active research efforts to develop accurate and precise methods to perform automated spectroscopic analysis and subsequently recognize gamma-ray signatures. In this work, the authors present a new method for radioisotope identification in gamma-ray spectra obtained with a low resolution radiation detector. The method fits the obtained spectrum with a linear combination of known template signature patterns. Coefficients of

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Niranjan, Giri. "A Review On Radioisotopes In Cancer Therapy." International Journal in Pharmaceutical Sciences 2, no. 2 (2024): 217–23. https://doi.org/10.5281/zenodo.10642989.

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This work points out importance of medical radioisotopes in nuclear medicine based on treatment and diagnosis of cancer. Moreover, possible production methods of medical   radioisotopes are evaluated, and an application for the production of two medical radioisotopes through neutron and deuteron induced reaction processes is discussed by comparing with experimental data in the literature.

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Maloth, Kotya Naik, Nagalaxmi Velpula, Sridevi Ugrappa, and Srikanth Kodangal. "Radioisotopes: An overview." International Journal of Case Reports and Images 5, no. 9 (2014): 604. http://dx.doi.org/10.5348/ijcri-201457-ra-10012.

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