Relevant bibliographies by topics / RAG1 expression

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'RAG1 expression'

Author: Grafiati
Published: 6 September 2023
Last updated: 31 July 2025

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Journal articles on the topic "RAG1 expression"

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Hnatova, Martina, Micheline Wésolowski-Louvel, Guenaëlle Dieppois, Julien Deffaud, and Marc Lemaire. "Characterization of KlGRR1 and SMS1 Genes, Two New Elements of the Glucose Signaling Pathway of Kluyveromyces lactis." Eukaryotic Cell 7, no. 8 (2008): 1299–308. http://dx.doi.org/10.1128/ec.00454-07.

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ABSTRACT The expression of the major glucose transporter gene, RAG1, is induced by glucose in Kluyveromyces lactis. This regulation involves several pathways, including one that is similar to Snf3/Rgt2-ScRgt1 in Saccharomyces cerevisiae. We have identified missing key components of the K. lactis glucose signaling pathway by comparison to the same pathway of S. cerevisiae. We characterized a new mutation, rag19, which impairs RAG1 regulation. The Rag19 protein is 43% identical to the F-box protein ScGrr1 of S. cerevisiae and is able to complement an Scgrr1 mutation. In the K. lactis genome, we
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Prior, C., P. Mamessier, H. Fukuhara, X. J. Chen, and M. Wesolowski-Louvel. "The hexokinase gene is required for transcriptional regulation of the glucose transporter gene RAG1 in Kluyveromyces lactis." Molecular and Cellular Biology 13, no. 7 (1993): 3882–89. http://dx.doi.org/10.1128/mcb.13.7.3882-3889.1993.

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The RAG1 gene of Kluyveromyces lactis encodes a low-affinity glucose/fructose transporter. Its transcription is induced by glucose, fructose, and several other sugars. The RAG4, RAG5, and RAG8 genes are trans-acting genes controlling the expression of the RAG1 gene. We report here the characterization of one of these genes, RAG5. The nucleotide sequence of the cloned RAG5 gene indicated that it encodes a protein that is homologous to hexokinases of Saccharomyces cerevisiae. rag5 mutants showed no detectable hexokinase or glucokinase activity, suggesting that the sugar kinase activity encoded b
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Prior, C., P. Mamessier, H. Fukuhara, X. J. Chen, and M. Wesolowski-Louvel. "The hexokinase gene is required for transcriptional regulation of the glucose transporter gene RAG1 in Kluyveromyces lactis." Molecular and Cellular Biology 13, no. 7 (1993): 3882–89. http://dx.doi.org/10.1128/mcb.13.7.3882.

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The RAG1 gene of Kluyveromyces lactis encodes a low-affinity glucose/fructose transporter. Its transcription is induced by glucose, fructose, and several other sugars. The RAG4, RAG5, and RAG8 genes are trans-acting genes controlling the expression of the RAG1 gene. We report here the characterization of one of these genes, RAG5. The nucleotide sequence of the cloned RAG5 gene indicated that it encodes a protein that is homologous to hexokinases of Saccharomyces cerevisiae. rag5 mutants showed no detectable hexokinase or glucokinase activity, suggesting that the sugar kinase activity encoded b
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Naik, Abani Kanta, Aaron T. Byrd, Aaron C. K. Lucander, and Michael S. Krangel. "Hierarchical assembly and disassembly of a transcriptionally active RAG locus in CD4+CD8+ thymocytes." Journal of Experimental Medicine 216, no. 1 (2018): 231–43. http://dx.doi.org/10.1084/jem.20181402.

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Expression of Rag1 and Rag2 is tightly regulated in developing T cells to mediate TCR gene assembly. Here we have investigated the molecular mechanisms governing the assembly and disassembly of a transcriptionally active RAG locus chromatin hub in CD4+CD8+ thymocytes. Rag1 and Rag2 gene expression in CD4+CD8+ thymocytes depends on Rag1 and Rag2 promoter activation by a distant antisilencer element (ASE). We identify GATA3 and E2A as critical regulators of the ASE, and Runx1 and E2A as critical regulators of the Rag1 promoter. We reveal hierarchical assembly of a transcriptionally active chroma
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Fisher, Megan, and Craig Bassing. "Pre-B cells suppress RAG expression in response to DNA double-strand breaks (HEM1P.225)." Journal of Immunology 194, no. 1_Supplement (2015): 50.8. http://dx.doi.org/10.4049/jimmunol.194.supp.50.8.

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Abstract The ability of the Rag1/Rag2 (RAG) endonuclease to assemble antigen receptor (AgR) genes is essential for adaptive immunity. However, aberrant induction or repair of RAG-induced DNA double strand breaks (DSBs) can lead to oncogenic AgR translocations. We have previously shown that RAG-induced DSBs in pre-B cells activate the ATM kinase to prevent RAG cleavage of the homologous allele, and to inhibit expression of Rag1 and Rag2. These breaks also suppress expression of Gadd45α, which promotes Rag1 and Rag2 transcription. Since DSBs induced by ionizing radiation (IR) signal through ATM
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Hao, Bingtao, Abani Kanta Naik, Akiko Watanabe, et al. "An anti-silencer– and SATB1-dependent chromatin hub regulates Rag1 and Rag2 gene expression during thymocyte development." Journal of Experimental Medicine 212, no. 5 (2015): 809–24. http://dx.doi.org/10.1084/jem.20142207.

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Rag1 and Rag2 gene expression in CD4+CD8+ double-positive (DP) thymocytes depends on the activity of a distant anti-silencer element (ASE) that counteracts the activity of an intergenic silencer. However, the mechanistic basis for ASE activity is unknown. Here, we show that the ASE physically interacts with the distant Rag1 and Rag2 gene promoters in DP thymocytes, bringing the two promoters together to form an active chromatin hub. Moreover, we show that the ASE functions as a classical enhancer that can potently activate these promoters in the absence of the silencer or other locus elements.
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Klemm, Lars, Srividya Swaminathan, Elli Papaemmanuil, et al. "Exposure to Inflammatory Immune Responses As Driver of Clonal Evolution in Childhood Acute Lymphoblastic Leukemia." Blood 126, no. 23 (2015): 166. http://dx.doi.org/10.1182/blood.v126.23.166.166.

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Abstract Background: Pediatric pre-B acute lymphoblastic leukemia (ALL) may develop from prenatal chromosomal translocations acquired in utero. For instance, the ETV6-RUNX1 gene rearrangement (~25% of childhood ALL) is found in the umbilical cord blood and Guthrie blood spots of 1 in 100 healthy newborns, however, only 1 in 14,000 carriers develop overt leukemia. The molecular mechanisms driving clonal evolution towards overt leukemia were not clear. Rationale: Activation Induced Cytidine Deaminase (AID) and Recombination Activation Genes 1 and 2 (RAG1-RAG2) are genetic modifiers of the immuno
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Swaminathan, Srividya, Lars Klemm, Eugene Park, et al. "Mechanisms of Clonal Evolution of Pre-Leukemic Clones in Childhood Pre-B Acute Lymphoblastic Leukemia." Blood 124, no. 21 (2014): 861. http://dx.doi.org/10.1182/blood.v124.21.861.861.

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Abstract Background and hypothesis: Childhood pre-B acute lymphoblastic leukemia (ALL) can frequently be retraced to a pre-leukemic clone carrying a prenatally acquired genetic lesion (e.g. ETV6-RUNX1gene rearrangement). After birth, pre-leukemic clones can acquire secondary mutations and, hence, evolve towards overt leukemia. While this concept is well established, the mechanism(s) driving clonal evolution are not known. Epidemiological findings hint to a role of delayed childhood infections and chronic inflammation as etiologic factors of childhood ALL, but do not illuminate mechanism of clo
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Lee, Baeck-seung, Joseph D. Dekker, Bum-kyu Lee, et al. "The BCL11A Transcription Factor Directly Activates RAG Gene Expression and V(D)J Recombination." Molecular and Cellular Biology 33, no. 9 (2013): 1768–81. http://dx.doi.org/10.1128/mcb.00987-12.

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Recombination-activating gene 1 protein (RAG1) and RAG2 are critical enzymes for initiating variable-diversity-joining (VDJ) segment recombination, an essential process for antigen receptor expression and lymphocyte development. The transcription factor BCL11A is required for B cell development, but its molecular function(s) in B cell fate specification and commitment is unknown. We show here that the major B cell isoform, BCL11A-XL, binds the RAG1 promoter and Erag enhancer to activate RAG1 and RAG2 transcription in pre-B cells. We employed BCL11A overexpression with recombination substrates
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Bories, JC, JM Cayuela, P. Loiseau, and F. Sigaux. "Expression of human recombination activating genes (RAG1 and RAG2) in neoplastic lymphoid cells: correlation with cell differentiation and antigen receptor expression." Blood 78, no. 8 (1991): 2053–61. http://dx.doi.org/10.1182/blood.v78.8.2053.2053.

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Abstract Regulation of V-(D)-J recombinations that occur in antigen receptor encoding genes remains poorly understood. Recently, two genes, RAG1 and RAG2, that are able to activate rearrangement of synthetic recombination substrates were cloned in mouse and a human gene homologous to RAG1 was described. To define the differentiation stages corresponding to RAG1 and RAG2 RNA expression, we have studied a large number of B- and T-lymphoid neoplasias. First, we show that a human gene homologous to the murine RAG2 is transcribed in humans. Moreover, using a polymerase chain reaction approach, we h
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Dissertations / Theses on the topic "RAG1 expression"

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Braga, Aécio Assunção. "Polimorfismos dos genes CD40, ICAM-1, VCAM, E-selectina, LIGHT, RAGE e CX3CR1 relacionados com inflamação e sua associação à obesidade." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/9/9136/tde-26052015-143307/.

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INTRODUÇÃO: A obesidade é um grave problema de saúde pública, sendo definida como o acúmulo excessivo de gordura, possivelmente decorrente do desequilíbrio, por um longo período, entre a quantidade de energia ingerida e o gasto energético. OBJETIVO: Investigar a contribuição dos polimorfismos dos genes CD40, ICAM-1, VCAM, E-selectina, LIGHT, RAGE e CX3CR1 na associação com a obesidade. CASUÍSTICA E MÉTODOS: O estudo foi realizado no Instituto Dante Pazzanese de Cardiologia (IDPC) e no Hospital Universitário da Universidade de São Paulo (HU/USP), com 199 indivíduos (40 com peso normal, 55 com s
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Lovejoy, Elizabeth A. "RAGE-based strategies for the control of gene expression." Thesis, University of Edinburgh, 1999. http://hdl.handle.net/1842/26699.

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The Cre/loxP site-specific recombinase system evolved within bacteriophage PI as a mechanism to maintain correct unit copy segregation of the prophage within host cells. This thesis reports the application of this system to regulate gene expression in murine cells. To regulate gene expression via RAGE (Recombination Activated Gene Expression) a novel floxed STOP cassette was designed, constructed and tested in murine embryonic fibroblasts (EF) and embryonic stem (ES) cells. When the floxed STOP cassette was used to regulate the expression of the Enhanced Green Fluorescent Protein (EGFP) marker
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Carvalho, Vanessa Isabel Dias Ribeiro de. "C. albicans Cek1 and Ras1: cloning, expression and purification." Master's thesis, Universidade de Aveiro, 2012. http://hdl.handle.net/10773/9526.

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Mestrado em Biologia Aplicada - Biologia Molecular e Celular<br>Candida albicans é um fungo polimórfico e patogénico que reside de forma comensal nas superfícies mucosas humanas. Este fungo apresenta um código genético ambíguo, uma vez que, o codão universal leucina CUG é predominantemente traduzido como serina (97%), mas também como leucina (3%). A análise de proteínas de C. albicans que contêm resíduos CUG em importantes posições funcionais, revela que a ambiguidade do codão modela a função da proteína e poderá ter um papel determinante nas vias de sinalização associadas a mudanças mo
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Kim, Sun. "HAPLOINSUFFICIENCY OF RAI1 AND ITS EFFECT ON BDNF EXPRESSION." VCU Scholars Compass, 2010. http://scholarscompass.vcu.edu/etd/165.

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Smith-Magenis Syndrome (SMS) [OMIM, #182290] is a congenital anomaly and mental retardation (MCA/MR) syndrome associated with deletion of chromosome17p11.2 [1]. The clinical phenotype has been well described and includes minor craniofacial anomalies, self-injurious behaviors as well as sleep disturbances, speech delays, and obesity [1,2,3]. The incidence of SMS is estimated to be ~ 1:15,000 - 25,000 births [2,6]. Among SMS patients, ~90% are comprised of 17p11.2 deletions, while ~10% have RAI1 mutations [8]. All 17p11.2 deletions associated with SMS include RAI1 deletion [10]. RAI1 is thou
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Chen, Suzi Su-Hsin, and suzi chen@med monash edu au. "Cyclooxygenase Expression in Human Diabetes." RMIT University. Medical Sciences, 2007. http://adt.lib.rmit.edu.au/adt/public/adt-VIT20080206.121439.

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Cyclooxygenase (COX) is the rate limiting enzyme that catalyses the production of prostanoids, which are crucial to vascular homeostasis. Evidence suggests that endothelial dysfunction and inflammation play a role in vascular complications in aging and diabetes. Previous animal studies by our laboratory at RMIT University reported enhanced COX expression with aging in rat aortas, platelets and monocytes. Potentially, alteration in COX expression may result in an imbalanced prostanoid production favoring the synthesis of vasoconstrictors and hence increase the risk of cardiovascular events in t
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Sikora, Kristin [Verfasser]. "RAGE-abhängige S100A8- und S100A9-Expression in humanen THP-1 Zellen / Kristin Sikora." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2009. http://d-nb.info/1023749920/34.

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Gonçalves, Carolina de Souza. "Expressão de proteínas RAP1 recombinantes e produção de anticorpos anti- RAP1: potencial uso como biomarcador no diagnóstico de tumores." s.n, 2014. https://www.arca.fiocruz.br/handle/icict/9945.

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Submitted by Nuzia Santos (nuzia@cpqrr.fiocruz.br) on 2015-04-10T12:21:27Z No. of bitstreams: 1 Dissertação final PDF.pdf: 2801952 bytes, checksum: 7ee702b1583d5a7e8912bdabb9228b92 (MD5)<br>Approved for entry into archive by Nuzia Santos (nuzia@cpqrr.fiocruz.br) on 2015-04-10T12:21:36Z (GMT) No. of bitstreams: 1 Dissertação final PDF.pdf: 2801952 bytes, checksum: 7ee702b1583d5a7e8912bdabb9228b92 (MD5)<br>Approved for entry into archive by Nuzia Santos (nuzia@cpqrr.fiocruz.br) on 2015-04-10T12:21:45Z (GMT) No. of bitstreams: 1 Dissertação final PDF.pdf: 2801952 bytes, checksum: 7ee702b1583d5a7e
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Di, Candia Leonarda. "The expression and function of RAGE and HMGB1 in airway structural cells in asthma." Thesis, University of Leicester, 2015. http://hdl.handle.net/2381/32339.

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Asthma is characterised by airway hyperresponsiveness, airflow obstruction, chronic inflammation and airway remodelling, with an increase in airway smooth muscle (ASM) mass and contractility. ASM also releases mediators that support inflammation and remodelling. High-mobility group box 1 (HMGB1) is a nuclear protein that is released by damaged/stressed cells and activated immune cells. HMGB1 signals through pattern recognition receptors (PRRs) including the receptor for advanced glycosylation end products (RAGE) to promote inflammation and tissue repair. HMGB1 binding and function are governed
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Lalk, Michael [Verfasser]. "Tumorregionen-abhängige Expression der Aminosäure-Sensoren MAP4K3, RagC und VPS34 in Glioblastomen / Michael Lalk." Magdeburg : Universitätsbibliothek, 2018. http://d-nb.info/1174626593/34.

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Rösch, Daniela. "Regulation der Expression der Rezeptoren für advanced glycation end products (RAGE) auf humanen Monozyten." [S.l. : s.n.], 2006.

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Books on the topic "RAG1 expression"

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Gillis, L. Jane. Expression and recombinase activity of RAG 1 and two splice variants of RAG 2 in mature human primary tonsilar B lymphocytes. National Library of Canada, 1999.

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Cherry, Myisha, and Owen Flanagan, eds. Moral Psychology of Anger. Rowman & Littlefield International Ltd, 2017. https://doi.org/10.5040/9798881817145.

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The Moral Psychology of Anger is the first comprehensive study of the moral psychology of anger from a philosophical perspective. In light of the recent revival of interest in emotions in philosophy and the current social and political interest in anger, this collection provides an inclusive view of anger from a variety of philosophical perspectives. The authors explore the nature of anger, explain its resilience in our emotional lives and normative frameworks, and examine what inhibits and encourages thoughts, feelings, and expressions of anger. The volume also examines rage, anger’s cousin,
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Expressing Rage. the Use of Violence in Sherman Alexie's Novel Indian Killer. GRIN Verlag GmbH, 2017.

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Hall, Ellen, and Richard Handley. High Schools in Crisis. Greenwood Publishing Group, Inc., 2004. http://dx.doi.org/10.5040/9798216972297.

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This book exposes the degree of rage today's teenagers feel and how our nation's schools are failing them, not just academically, but in just about every way imaginable. Hall and Handley propose practical techniques, procedures, and core values that can make high school a safe learning environment once again. Drawing from their many years of experience administering a high school that provided a safe and fulfilling learning environment, they introduce readers to teaching techniques, administrative policies, and design ideas that encourage students to speak out, express their indomitable ideali
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Ferrazza, Daniele de Andrade, and Hilusca Alves Leite. Mulheres e feminismo: perspectivas históricas e desafios atuais. Edufatecie, 2022. http://dx.doi.org/10.33872/edufatecie.mulheresefeminismo.

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O livro Mulheres e feminismo: perspectivas históricas e desafios atuais se propõe a apresentar, nas diferentes perspectivas adotadas pelas diversas autoras, discussões sobre as movimentações feministas de suas trajetórias históricas aos debates contemporâneos. Pretende, também, sensibilizar e mobilizar mulheres em diferentes contextos para uma única luta relacionada aos enfrentamentos contra relações patriarcais, machistas e falocêntricas que reproduzem violências de gênero e impedem a igualdade de direitos de mulheres na contemporaneidade brasileira (RAGO; PELEGRINI, 2019). A coletânea de tex
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Book chapters on the topic "RAG1 expression"

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Shirude, Snehalata B., and Satish R. Kolhe. "Recognizing Raga of Indian Classical Songs Using Regular Expressions." In Intelligent Systems for Smart Cities. Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-99-6984-5_24.

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Ablin, Jason. "Rage On! Gender/Sex, Emotional, and Physical Expression in Schools." In The Gender Equation in Schools. Routledge, 2022. http://dx.doi.org/10.4324/9781003217022-8.

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Ttofa, Juliette, and Paul Greenhouse. "Rage: the shadow side of unspeakable pain." In Using the Expressive Arts with Children and Young People Who Have Experienced Trauma. Routledge, 2022. http://dx.doi.org/10.4324/9781003121411-9.

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van Lent, Anja U., Mireille Centlivre, Maho Nagasawa, et al. "In Vivo Modulation of Gene Expression by Lentiviral Transduction in “Human Immune System” Rag2−/−γc −/− Mice." In Methods in Molecular Biology. Humana Press, 2006. http://dx.doi.org/10.1007/978-1-60761-421-0_6.

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Evans, Dorinda. "5. A Challenge to International Neoclassicism." In William Rimmer. Open Book Publishers, 2022. http://dx.doi.org/10.11647/obp.0304.05.

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Rimmer's major sculptural works, such as St. Stephen, Falling Gladiator, Dying Centaur, and Osirus (destroyed), were created for exhibition and in response to the international neoclassical movement. In different ways, they are actually critiques of the rage for neoclassicism. Much of what Rimmer was trying to do is conveyed in his teaching, and he used his exhibited art as an extension of this. He wanted an art based not on copying from antique casts or from life but, rather, on the artist's own imagination so that the work is self-expressive. The fact that the man in Falling Gladiator assume
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Rani, Ruma, Parth Malik, and Tapan Kumar Mukherjee. "Receptor for Advanced Glycation End Products in Health and Physiology." In Glycosylation and Glycation in Health and Diseases. BENTHAM SCIENCE PUBLISHERS, 2025. https://doi.org/10.2174/9789815322521125010007.

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The transmembrane protein receptor for advanced glycation end products (mRAGEs) is recognized as an immunoglobulin class of molecule. Mammalian cells produce a carboxy terminus truncated version of RAGE, either as endogenous soluble RAGE (esRAGE) or soluble RAGE (sRAGE), both being generated via proteolytic cleavage or alternative mRAGE-mRNA splicing. Through its extracellular domains (V, C1, and C2), RAGE interacts with seemingly unrelated ligands such as advanced glycation end products (AGEs), high mobility group box protein 1 (HMGB1), S100/calgranulin family, lysophosphatidic acid (LPA), ol
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Malik, Parth, Ruma Rani, and Tapan Kumar Mukherjee. "Receptor for Advanced Glycation End Products in Pulmonary Diseases." In Glycosylation and Glycation in Health and Diseases. BENTHAM SCIENCE PUBLISHERS, 2025. https://doi.org/10.2174/9789815322521125010009.

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The receptor for advanced glycation end products (RAGE) is characterized as a multi-ligand pattern recognition receptor molecule exhibiting physiologically profuse expression in the lung alveolar type 1 (AT-1) epithelial cell’s basolateral region. Advanced glycation end products (AGEs) are the most prominent among the multiple ligands of RAGE in lung tissues. Other major RAGE ligands comprise high mobility group box protein 1 (HMGB-1) and S100/calgranulin. In various pathophysiological conditions, lung tissues express the supraphysiological level of RAGE and its multiple ligands. In physiologi
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Rani, Ruma, Parth Malik, and Tapan Kumar Mukherjee. "Receptor for Advanced Glycation End Products in Various Types of Cancers." In Glycosylation and Glycation in Health and Diseases. BENTHAM SCIENCE PUBLISHERS, 2025. https://doi.org/10.2174/9789815322521125010011.

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The receptor for advanced glycation end products (RAGE) was first isolated and characterized in the bovine lungs. Mammalian lungs express a relatively higher level of RAGE than other organs of the mammalian body. Physiologically, RAGE guards from lung cancer development owing to which, a diminished RAGE expression is implicated in the lung cancer complication. Opposed to this, a high-level RAGE expression is associated with the development of various cancers including breast, ovary, prostate, pancreatic, colon and colorectal, hepatocellular, melanoma, and neuronal. Interactions of RAGE and its
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Malik, Parth, Ruma Rani, and Tapan Kumar ,. Mukherjee. "Receptor for Advanced Glycation End Products in Neuronal Pathophysiology." In Glycosylation and Glycation in Health and Diseases. BENTHAM SCIENCE PUBLISHERS, 2025. https://doi.org/10.2174/9789815322521125010012.

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The receptor for advanced glycation end products (RAGE) is a multi-ligand receptor molecule expressed in the cells of the nervous system (neurons and glial cells). Compared to embryonic cells, RAGE expression is significantly decreased within the adult tissues, including the nervous system. Various RAGE ligands such as amyloidbeta peptide (Aβ-peptide), high mobility group box protein 1 (HMGB1), S100/calgranulin, and advanced glycation end products (AGEs) are expressed by the cells of the nervous system. Several studies have predicted the role of RAGE in neurogenesis. Interaction of RAGE with i
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Buckle, Irina, and Josephine M. Forbes. "The Role of the Receptor for Advanced Glycation Endproducts (RAGE) in Type 1 Diabetes: An Immune Cell Perspective." In Type 1 Diabetes Mellitus [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.108528.

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Type 1 diabetes (T1DM) is an autoimmune disorder resulting in destruction of the insulin producing pancreatic β-cells that reside in the Islets of Langerhans. Despite significant progress in the understanding of T1DM pathogenesis, some fundamental contributing mechanisms remain to be fully elucidated. The receptor for advanced glycation end products (RAGE) and its ligands are increasingly believed to play a role in the development of T1DM, but this is not well understood. The location of RAGE gene is shared with major T1DM genetic susceptibility loci on chromosome 6 and polymorphism of this re
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Conference papers on the topic "RAG1 expression"

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Ge, zheng, Qi Han, Jinlong Ma, et al. "Abstract 5507: RAG1 high expression associated with IKZF1 dysfunction in adult B-cell acute lymphoblastic leukemia." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-5507.

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de Souza Xavier Costa, Natália, Giovana Da Costa Sigrist, Marisa Dolhnikoff, and Luiz Fernando Ferraz Da Silva. "RAGE expression in lung tissue of ARDS and septic patients." In ERS International Congress 2020 abstracts. European Respiratory Society, 2020. http://dx.doi.org/10.1183/13993003.congress-2020.2752.

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Vieira, Paula Cristina de Vasconcelos, Adriano de Paula Sabino, Jaqueline Germano de Oliveira, Marcelo Antônio Pascoal Xavier, Annamaria Ravara Vago, and Maria Gabrielle de Lima Rocha. "Avaliação de RAP1 como biomarcador da neoplasia intraepitelial cervical." In XIII Congresso da Sociedade Brasileira de DST - IX Congresso Brasileiro de AIDS - IV Congresso Latino Americano de IST/HIV/AIDS. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/dst-2177-8264-202133p067.

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Introdução: Mundialmente, o carcinoma de colo uterino associado ao papilomavírus humano está entre as maiores causas de morte relacionadas ao câncer na população feminina. Nos últimos anos, a detecção de lesões pré-neoplásicas mediante a ação de programas consolidados de rastreamento, prevenção e acompanhamento clínico permitiram a redução das taxas de câncer de colo em diversos países. Entretanto, essa neoplasia ainda é muito frequente. Esse problema tem fortalecido a procura por biomarcadores que possam aumentar a eficiência do rastreamento. Entre esses biomarcadores está RAP1, pequena GTPas
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O'Carroll, Mark, John Huetsch, James Hamilton, Lindsey Moser, Sudar Alagarsamy, and Matthias Salathe. "Late Breaking Abstract - A first-in-human study of ARO-RAGE, an RNAi therapy designed to silence pulmonary RAGE expression." In ERS International Congress 2023 abstracts. European Respiratory Society, 2023. http://dx.doi.org/10.1183/13993003.congress-2023.oa2601.

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Sabri, Helen, and Mohammed Merza. "Rac-1 Inhibitor Attenuates Neutrophil Infiltration and Tissue Damage in Severe Acute Pancreatitis." In 5th International Conference on Biomedical and Health Sciences. Cihan University-Erbil, 2024. http://dx.doi.org/10.24086/biohs2024/paper.1359.

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Background: Acute pancreatitis is a common inflammatory disease of the exocrine pancreas, characterized by a mortality rate ranging from 1% to 5%. This condition has the potential to lead to organ dysfunction, pancreatic necrosis, and subsequent organ failure. Aim: Rac1, a G-protein with a molecular weight of approximately 21 kD, has been demonstrated to govern various platelet functions. We hypothesized that the inhibition of Rac-1 signaling could be implicated in severe acute pancreatitis (AP). Our study aimed to explore the impact of a Rac- 1 inhibitor on neutrophil release and its potentia
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Perkins, Timothy, Elizabeth Oczypok, Regina Dutz, and Tim Oury. "RAGE-dependent VCAM-1 expression in the pulmonary endothelium mediates IL-33 induced asthma pathogenesis." In ERS International Congress 2017 abstracts. European Respiratory Society, 2017. http://dx.doi.org/10.1183/1393003.congress-2017.pa4915.

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Kasahara, D. I., A. Nicholas, T. Reed, et al. "Silencing RAGE Expression with a Lung-Targeted RNAi Trigger Delivery Platform Suppresses Pulmonary Allergic Inflammation." In American Thoracic Society 2022 International Conference, May 13-18, 2022 - San Francisco, CA. American Thoracic Society, 2022. http://dx.doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5013.

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Aquino, Isabella V. de, Matheus M. dos Santos, Carina F. Dorneles, and Jônata T. Carvalho. "Extracting Information from Brazilian Legal Documents with Retrieval Augmented Generation." In Anais Estendidos do Simpósio Brasileiro de Banco de Dados. Sociedade Brasileira de Computação - SBC, 2024. http://dx.doi.org/10.5753/sbbd_estendido.2024.244241.

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Extracting information from unstructured data is a challenge that has drawn increasing attention over time due to the exponential growth of stored digital data in modern society. Large Language Models (LLMs) have emerged as powerful tools that benefit from this abundance and have shown remarkable capabilities in Natural Language Processing tasks. Nonetheless, these models still encounter limitations on extraction tasks. Retrieval Augmented Generation (RAG) is a novel approach that combines classic retrieval techniques and LLMs to address some of these limitations. This paper proposes a workflo
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AI, Cabrera-García, M. Protschka, G. Alber, et al. "Dysregulation of gastrointestinal RAGE (receptor for advanced glycation end products) expression in dogs with inflammatory bowel disease." In 29. Jahrestagung der FG „Innere Medizin und klinische Labordiagnostik“ der DVG (InnLab) – Teil 2: Poster. Georg Thieme Verlag KG, 2021. http://dx.doi.org/10.1055/s-0041-1723879.

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Mangalmurti, Nilam S., Jessica Friedman, Liang Chuan Wang, et al. "Banked RBCs Induce The Expression Of The Receptor For Advanced Glycation Endproducts (RAGE) On Lung Endothelial Cells." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a5498.

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Reports on the topic "RAG1 expression"

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Su, Bing. The Role of mTOR Signaling in the Regulation of RAG Expression and Genomic Stability during B Lymphocyte Development. Defense Technical Information Center, 2013. http://dx.doi.org/10.21236/ada588301.

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