Academic literature on the topic 'Randomized controlled trial'

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Journal articles on the topic "Randomized controlled trial"

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G, Girish, and Ashok Deorari. "Randomized Controlled Trial." Journal of Neonatology 20, no. 1 (March 2006): 64–68. http://dx.doi.org/10.1177/0973217920060112.

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Castro, Fernando J., Baker Al-Khairi, Harjinder Singh, Mosaab Mohameden, Kanwarpreet Tandon, and Rocio Lopez. "Randomized Controlled Trial." Journal of Clinical Gastroenterology 53, no. 10 (2019): 724–30. http://dx.doi.org/10.1097/mcg.0000000000001213.

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Vautrin, M., G. Kaminski, B. Barimani, J. Elmers, V. Philippe, S. Cherix, E. Thein, O. Borens, and F. Vauclair. "Does candidate for plate fixation selection improve the functional outcome after midshaft clavicle fracture? A systematic review of 1348 patients." Shoulder & Elbow 11, no. 1 (June 4, 2018): 9–16. http://dx.doi.org/10.1177/1758573218777996.

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Introduction The hypothesis of this study was that patient selection for midshaft clavicle fracture (open reduction internal fixation with plate versus conservative) would give better functional outcome than random treatment allocation. Methods We performed a systematic literature search for primary studies providing functional score and non-union rate after conservative or surgical management of midshaft clavicle fractures. Six randomized controlled trial and 19 non-randomized controlled trial studies encompassing a total of 1348 patients were included. Results Patients treated with surgical management were found to have statistically superior Constant scores in non-randomized controlled trials than in randomized controlled trials (94.76 ± 6.4 versus 92.49 ± 6.2; p < 0.0001). For conservative treatment, randomized controlled trials were found to have significantly better functional outcome. The prevalence of non-union (6.1%) did not show significant statistical difference between non-randomized controlled trial and randomized controlled trial studies. The functional outcome after surgical management was significantly higher than after conservative management in both randomized controlled trial and non-randomized controlled trial groups. The non-union rate after surgery (1.1% for both non-randomized controlled trial and randomized controlled trial) was significantly lower than following conservative treatment (9.9% non-randomized controlled trial versus 15.1% randomized controlled trial). Discussion This review shows that patient selection for surgery may influence functional outcome after midshaft clavicle fracture. Our results also confirm that plate fixation provides better functional outcome and lower non-union rate.
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Takroni, Radwan, Sunjay Sharma, Kesava Reddy, Nirmeen Zagzoog, Majid Aljoghaiman, Mazen Alotaibi, and Forough Farrokhyar. "Randomized controlled trials in neurosurgery." Surgical Neurology International 13 (August 26, 2022): 379. http://dx.doi.org/10.25259/sni_1032_2021.

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Randomized controlled trials (RCTs) have become the standard method of evaluating new interventions (whether medical or surgical), and the best evidence used to inform the development of new practice guidelines. When we review the history of medical versus surgical trials, surgical RCTs usually face more challenges and difficulties when conducted. These challenges can be in blinding, recruiting, funding, and even in certain ethical issues. Moreover, to add to the complexity, the field of neurosurgery has its own unique challenges when it comes to conducting an RCT. This paper aims to provide a comprehensive review of the history of neurosurgical RCTs, focusing on some of the most critical challenges and obstacles that face investigators. The main domains this review will address are: (1) Trial design: equipoise, blinding, sham surgery, expertise-based trials, reporting of outcomes, and pilot trials, (2) trial implementation: funding, recruitment, and retention, and (3) trial analysis: intention-to-treat versus as-treated and learning curve effect.
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Al Abdukareem, Abdulmajeed. "Randomized, placebo-controlled trial." Annals of Saudi Medicine 24, no. 2 (March 2004): 145. http://dx.doi.org/10.5144/0256-4947.2004.145.

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Forster, Anne, John Young, Katie Chapman, Jane Nixon, Anita Patel, Ivana Holloway, Kirste Mellish, et al. "Cluster Randomized Controlled Trial." Stroke 46, no. 8 (August 2015): 2212–19. http://dx.doi.org/10.1161/strokeaha.115.008585.

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Healy, Ciaran, Aina V. H. Greig, Adrian D. Murphy, Christopher Powell, Richard J. Pinder, Samer Saour, Christopher Abela, William Knight, and Jenny L. C. Geh. "Prospective Randomized Controlled Trial." Plastic and Reconstructive Surgery 132, no. 1 (July 2013): 139e—146e. http://dx.doi.org/10.1097/prs.0b013e318299c6f4.

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Field, David, and Diana Elbourne. "The randomized controlled trial." Current Paediatrics 13, no. 1 (February 2003): 53–57. http://dx.doi.org/10.1054/cupe.2003.0409.

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Murphy, Adrian D., Aina V. H. Greig, Chris A. Powell, Richard J. Pinder, Samer Saour, Jenny L. C. Geh, and Ciaran M. Healy. "Prospective Randomized Controlled Trial." Plastic and Reconstructive Surgery 130 (November 2012): 50–51. http://dx.doi.org/10.1097/01.prs.0000421755.15147.58.

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Montgomery, Michelle O., Jessica J. Kram, Marie M. Forgie, Ana C. Perez Moreno, and Taylor Romdenne. "A Randomized Controlled Trial." Obstetrics & Gynecology 135 (May 2020): 167S. http://dx.doi.org/10.1097/01.aog.0000663980.54152.fb.

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Dissertations / Theses on the topic "Randomized controlled trial"

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Möller, Hans. "Isthmic spondylolisthesis in adults : a randomized controlled trial /." Stockholm, 1999. http://diss.kib.ki.se/1999/91-628-3834-2/.

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Doiron, Jason. "Prevention of pathological gambling a randomized controlled trial /." access full-text online access from Digital Dissertation Consortium, 2005. http://libweb.cityu.edu.hk/cgi-bin/er/db/ddcdiss.pl?NR25497.

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Wong, Ho-hang Anthony. "A randomized controlled trial of home tooth-whitening products." Click to view the E-thesis via HKUTO, 2004. http://sunzi.lib.hku.hk/hkuto/record/B3195439X.

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Bukusi, Elizabeth Anne. "Bacterial vaginosis : a randomized controlled trial to prevent recurrence /." Thesis, Connect to this title online; UW restricted, 2006. http://hdl.handle.net/1773/10880.

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Wong, Ho-hang Anthony, and 黃浩行. "A randomized controlled trial of home tooth-whitening products." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2004. http://hub.hku.hk/bib/B3195439X.

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Chong, Shing-kan Patrick. "A randomized controlled trial for exercise prescription in general practice." Click to view the E-thesis via HKUTO, 2003. http://sunzi.lib.hku.hk/hkuto/record/B31970977.

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Baumueller, Eva. "Electromyogram-Biofeedback in Patients with Fibromyalgia A Randomized Controlled Trial." Diss., lmu, 2009. http://nbn-resolving.de/urn:nbn:de:bvb:19-109423.

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Hoskins, Eric William. "Edmonson-Zagreb measles vaccine : randomized controlled clinical trial in Sudan." Thesis, University of Oxford, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.386576.

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Chong, Shing-kan Patrick, and 莊承謹. "A randomized controlled trial for exercise prescription in general practice." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2003. http://hub.hku.hk/bib/B31970977.

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Hay, Jacqueline. "Physical activity intensity and visceral adiposity: a randomized controlled trial." American Medical Association, 2012. http://hdl.handle.net/1993/16315.

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Background: Physical activity (PA) reduces visceral adipose tissue (VAT) in adults; however, the dose to reduce VAT in youth is unclear. Objective: To examine whether high intensity PA preferentially reduces waist circumference (WC) and VAT compared to lower intensity PA. Design: Randomized controlled trial. Participants: Youth were 13-18yrs, overweight, with one additional risk factor for type 2 diabetes (T2DM). Intervention: 6-months, exercising 3 times/week at a high intensity (70-85% of Heart Rate Reserve HRR), or low intensity (40-55% HRR). Primary outcome: VAT (cm2) measured by MRI at L4-L5, and WC at the height of the iliac crest (cm). Results: 94 Youth were randomized to either high intensity (n=30); low intensity (n=32) or control (n=32). Changes in WC and VAT were not significant across groups. A trend towards a reduction in VAT in the training groups, compared to controls was demonstrated in sub-analysis (-14.3 ± 9.6 % vs. +0.01 ± 0.4 %, p= 0.059). Peak fitness increased significantly in both the high and low intensity arms (1.3 ± 0.6 and 1.4 ± 0.6 ml/kg/min, p < 0.05). Conclusions: Training at 55-65% HRR improves fitness by ~10%, and ~2 days/week elicits modest non-significant reductions in VAT in overweight youth.
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Books on the topic "Randomized controlled trial"

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Bothwell, Laura. The Emergence of the Randomized Controlled Trial: Origins to 1980. [New York, N.Y.?]: [publisher not identified], 2014.

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Brymer, Christopher David. A randomized, double-blind, placebo-controlled crossover trial of nimodipine for geriatric urge incontinence. Ottawa: National Library of Canada = Bibliothèque nationale du Canada, 1999.

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Davies, Allyson Ross. Consumer acceptance of prepaid and fee-for-service medical care : results from a randomized controlled trial. Santa Monica, CA: Rand, 1986.

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Travis, Heather E. Evaluating three self-help smoking cessation interventions for post-secondary smokers: A randomized controlled trial on six Ontario campuses. St. Catharines, Ont: Brock University, Dept. of Community Health Sciences, 2003.

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Akoury, Hani. A randomized controlled trial to evaluate the use of misoprostol for second trimester pregnancy temination associated with fetal malformation. Ottawa: National Library of Canada, 2002.

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1941-, Lohr Kathleen N., United States. Dept. of Health and Human Services, and Rand Health Insurance Experiment, eds. Use of medical care in the Rand Health Insurance Experiment: Diagnosis- and service-specific analysis in a randomized controlled trial. Santa Monica, CA: Rand, 1986.

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A, Leibowitz Arleen, Rand Corporation, United States. Dept. of Health and Human Services., and Rand Health Insurance Experiment, eds. The Effect of cost-sharing on the use of medical services by children: Interim results from a randomized controlled trial. Santa Monica, CA: Rand, 1985.

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Jadad, Alejandro R., and Murray W. Enkin, eds. Randomized Controlled Trials. Oxford, UK: Blackwell Publishing Ltd, 2007. http://dx.doi.org/10.1002/9780470691922.

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Trained, Peer Mentorship and Veteran Support Organization Membership to Assist Transitioning Veterans: A Multi-arm, Parallel Randomized Controlled Trial (A Preliminary Investigation). [New York, N.Y.?]: [publisher not identified], 2018.

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Finkel, Angela M. Childbirth satisfaction of participants in a randomized controlled trial of the treatment of postterm pregnancy induction of labour versus serial antenatal monitoring. Ottawa: National Library of Canada, 1990.

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Book chapters on the topic "Randomized controlled trial"

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Molina, Kristine M., Kristine M. Molina, Heather Honoré Goltz, Marc A. Kowalkouski, Stacey L. Hart, David Latini, J. Rick Turner, et al. "Randomized Controlled Trial." In Encyclopedia of Behavioral Medicine, 1620. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-1005-9_1059.

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Masters, Kevin S. "Randomized Controlled Trial." In Encyclopedia of Sciences and Religions, 1947. Dordrecht: Springer Netherlands, 2013. http://dx.doi.org/10.1007/978-1-4020-8265-8_200344.

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Shoff, William H., Catherine T. Shoff, Suzanne M. Shepherd, Jonathan L. Burstein, Calvin A. Brown, Ashita J. Tolwani, Bala Venkatesh, et al. "Randomized Controlled Trial (RCT)." In Encyclopedia of Intensive Care Medicine, 1951. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-00418-6_3279.

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Molina, Kristine M., Kristine M. Molina, Heather Honoré Goltz, Marc A. Kowalkouski, Stacey L. Hart, David Latini, J. Rick Turner, et al. "Randomized Controlled Clinical Trial." In Encyclopedia of Behavioral Medicine, 1620. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-1005-9_101436.

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Nahler, Gerhard. "randomized controlled clinical trial." In Dictionary of Pharmaceutical Medicine, 155. Vienna: Springer Vienna, 2009. http://dx.doi.org/10.1007/978-3-211-89836-9_1182.

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Boermeester, Marja. "Onderzoeksprotocol: randomized controlled trial." In Promoveren doe je zo!, 21–25. Houten: Bohn Stafleu van Loghum, 2013. http://dx.doi.org/10.1007/978-90-313-9952-9_5.

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Olsen, Jørn, Kaare Christensen, Jeff Murray, and Anders Ekbom. "The Randomized Controlled Trial (RCT)." In An Introduction to Epidemiology for Health Professionals, 81–84. New York, NY: Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-1497-2_12.

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Salsburg, David S. "The Randomized Controlled Clinical Trial." In The Use of Restricted Significance Tests in Clinical Trials, 3–9. New York, NY: Springer New York, 1992. http://dx.doi.org/10.1007/978-1-4612-4414-1_1.

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Molina, Kristine M., Kristine M. Molina, Heather Honoré Goltz, Marc A. Kowalkouski, Stacey L. Hart, David Latini, J. Rick Turner, et al. "Randomized Concurrently Controlled Clinical Trial." In Encyclopedia of Behavioral Medicine, 1620. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-1005-9_101435.

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Lesaffre, Emmanuel. "The Randomized Controlled Trial: Methodological Perspectives." In Understanding Evidence-Based Rheumatology, 159–78. Cham: Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-08374-2_7.

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Conference papers on the topic "Randomized controlled trial"

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Ben Hmida, Lenda, Islam Mejri, Marwa Kacem, Selsabil Daboussi, Samira Mhamdi, Chiraz Aichaouia, and Zied Moatemri. "Conscious sedation in bronchoscopy:A randomized controlled trial." In ERS International Congress 2023 abstracts. European Respiratory Society, 2023. http://dx.doi.org/10.1183/13993003.congress-2023.pa1791.

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Rohrer, Doug. "Cluster Randomized Controlled Trial of Interleaved Mathematics Practice." In 2019 AERA Annual Meeting. Washington DC: AERA, 2019. http://dx.doi.org/10.3102/1427791.

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Hauck, K., J. Lindemann, MO Scheithauer, TK Hoffmann, and F. Sommer. "Relevance of turbinoplasty in rhinosurgery – a randomized controlled trial." In Abstract- und Posterband – 90. Jahresversammlung der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Hals-Chirurgie e.V., Bonn – Digitalisierung in der HNO-Heilkunde. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1686727.

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Izquierdo-Pulido, Maria, María Fernanda Zerón-Rugerio, Aradeisy Ibarra-Picón, María Diez-Hernández, Francisco Pérez-Cano, and Trinitat Cambras. "Walnut Consumption Improves Sleep Quality: A Randomized-Controlled Trial." In European Nutrition Conference. Basel Switzerland: MDPI, 2024. http://dx.doi.org/10.3390/proceedings2023091381.

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Bakhru, R., L. Flores, J. M. Cain, V. Province, J. Fanning, H. Rawal, R. Bundy, et al. "A Randomized Controlled Trial of Post-ICU Telehealth Care." In American Thoracic Society 2024 International Conference, May 17-22, 2024 - San Diego, CA. American Thoracic Society, 2024. http://dx.doi.org/10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a5053.

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Eder, T., B. Kabon, E. Fleischmann, M. Hecking, and M. Ernstbrunner. "Bioimpedance Spectroscopy Improves Perioperative Fluid Therapy: a Randomized Controlled Trial." In AIC 2018. Georg Thieme Verlag KG, 2018. http://dx.doi.org/10.1055/s-0038-1675484.

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Khan, S. H., R. Purpura, S. Durrani, S. Wang, H. Lindroth, J. Meeker, P. Hanneman, C. Xu, and B. A. Khan. "Decreasing Delirium Through Music (DDM): A Randomized Controlled Feasibility Trial." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4101.

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Wand, Ori, Elad Guber, Alexander Guber, Gali Epstein-Shochet, Lilach Israeli-Shani, and David Shitrit. "Inhalations of Tranexamic Acid for hemoptysis: A randomized controlled trial." In ERS International Congress 2018 abstracts. European Respiratory Society, 2018. http://dx.doi.org/10.1183/13993003.congress-2018.pa4409.

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Prasad, Bharati, Miodrag G. Radulovacki, and David W. Carley. "Randomized Placebo Controlled Trial Of Dronabinol In Obstructive Sleep Apnea." In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a2720.

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Rassouli, Frank, Florent Baty, Malcolm Kohler, Daiana Stolz, Robert Thurnheer, Thomas Brack, Christian Kähler, et al. "Telehealth vs. standard care in COPD – a randomized controlled trial." In ERS International Congress 2020 abstracts. European Respiratory Society, 2020. http://dx.doi.org/10.1183/13993003.congress-2020.2666.

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Reports on the topic "Randomized controlled trial"

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Ruzek, Josef. Randomized, Controlled Trial of CBT Training for PTSD Providers. Fort Belvoir, VA: Defense Technical Information Center, October 2013. http://dx.doi.org/10.21236/ada593743.

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Moss, David, Paul Crawford, Heather Pickett, and Eric Abbott. Ear Acupuncture for Acute Sore Throat: A Randomized Controlled Trial. Fort Belvoir, VA: Defense Technical Information Center, September 2014. http://dx.doi.org/10.21236/ada610454.

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Luxton, David D., Nigel Bush, Gregory Gahm, Mark Reger, Nancy Skopp, Janet Kemp, Tina Lee, Robert McLay, Joan Chipps, and Daphne Brown. Caring Letters for Military Suicide Prevention: A Randomized Controlled Trial. Fort Belvoir, VA: Defense Technical Information Center, February 2015. http://dx.doi.org/10.21236/ada614508.

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Luxton, David, Nigel Bush, Gregory Gahm, Mark Reger, Nancy Skopp, Janet Kemp, Jennifer Hoblyn, Robert McLay, Helenna Nakama, and Joan Chipps. Caring Letters for Military Suicide Prevention: A Randomized Controlled Trial. Fort Belvoir, VA: Defense Technical Information Center, February 2012. http://dx.doi.org/10.21236/ada574923.

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Luxton, David. Caring Letters for Military Suicide Prevention: A Randomized Controlled Trial. Fort Belvoir, VA: Defense Technical Information Center, February 2014. http://dx.doi.org/10.21236/ada596676.

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Conti, Gabriella, Bartosz Woda, Alessandra Voena, Shailender Swaminathan, Morgen Miller, Cynthia Kinnan, Kosuke Imai, Phoebe Holtzman, and Anup Malani. Effect of health insurance in India: a randomized controlled trial. The IFS, December 2021. http://dx.doi.org/10.1920/wp.ifs.2021.4721.

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Malani, Anup, Phoebe Holtzman, Kosuke Imai, Cynthia Kinnan, Morgen Miller, Shailender Swaminathan, Alessandra Voena, Bartosz Woda, and Gabriella Conti. Effect of Health Insurance in India: A Randomized Controlled Trial. Cambridge, MA: National Bureau of Economic Research, December 2021. http://dx.doi.org/10.3386/w29576.

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Blanco, Mariana, and Juan F. Vargas. Empowering IDPs with SMS: A Randomized Controlled Trial in Bogota. Inter-American Development Bank, December 2010. http://dx.doi.org/10.18235/0011196.

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This paper studied whether the use of short message service (SMS) technology effectively informed Bogota's population of internally displaced persons (IDPs) about its eligibility to receive social benefits. Half of the sample population was randomly informed of their eligibility via SMS and their awareness of available benefits was estimated. On average, treated households are more aware of their rights; however, awareness varies across benefit type. The study recommends expanding the use of SMS as a policy instrument and as a means for empowering IDPs.
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Roy, Michael J. Randomized, Controlled Trial of Combination Treatment With Pyridostigmine, DEET, and Teremethrin. Fort Belvoir, VA: Defense Technical Information Center, July 2005. http://dx.doi.org/10.21236/ada446574.

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Luo, Minjing, Yilin Li, Yingqiao Wang, Jinghan Huang, Zhihan Liu, Yicheng Gao, Qianyun Chai, Yuting Feng, Jianping Liu, and Yutong Fei. The Fragility of Statistically Significant Findings from Depression Randomized Controlled Trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, April 2023. http://dx.doi.org/10.37766/inplasy2023.4.0086.

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Review question / Objective: The Fragility of Statistically Significant Findings from Depression Randomized Controlled Trials. Condition being studied: Depression is a mental disorder characterized by a range of symptoms, including loss of memory and sleep, decreased energy, feelings of guilt or low mood, disturbed appetite, poor concentration, and an increased risk of suicide. According to a systematic analysis of the Global Burden of Disease Study 2019, depression is recognized as the leading cause of disease burden for mental disorders, accounting for the largest proportion of disability-adjusted life years (DALYs) at 37.3%. The fragility index (FI), which is the minimum number of changes from events to non-events resulting in loss of statistical significance, has been suggested as a means to aid the interpretation of trial results, as the potential inadequacy about robustness of threshold P-value as a tool for reporting binary outcomes in clinical trials. In this systematic review, we want to calculate the FI of randomized controlled trials (RCTs) in depression.
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