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Dissertations / Theses on the topic 'Randomized Controlled Trial Design'

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1

Spieth, Peter Markus, Anne Sophie Kubasch, Ana Isabel Penzlin, Ben Min-Woo Illigens, Kristian Barlinn, and Timo Siepmann. "Randomized controlled trials - a matter of design." Dove Medical Press, 2016. https://tud.qucosa.de/id/qucosa%3A29007.

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Randomized controlled trials (RCTs) are the hallmark of evidence-based medicine and form the basis for translating research data into clinical practice. This review summarizes commonly applied designs and quality indicators of RCTs to provide guidance in interpreting and critically evaluating clinical research data. It further reflects on the principle of equipoise and its practical applicability to clinical science with an emphasis on critical care and neurological research. We performed a review of educational material, review articles, methodological studies, and published clinical trials u
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Spieth, Peter Markus, Anne Sophie Kubasch, Ana Isabel Penzlin, Ben Min-Woo Illigens, Kristian Barlinn, and Timo Siepmann. "Randomized controlled trials - a matter of design." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2017. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-215848.

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Randomized controlled trials (RCTs) are the hallmark of evidence-based medicine and form the basis for translating research data into clinical practice. This review summarizes commonly applied designs and quality indicators of RCTs to provide guidance in interpreting and critically evaluating clinical research data. It further reflects on the principle of equipoise and its practical applicability to clinical science with an emphasis on critical care and neurological research. We performed a review of educational material, review articles, methodological studies, and published clinical trials u
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Reichmann, William Michael. "Methods in subgroup analysis: estimation of risk and implications for randomized controlled trial design." Thesis, Boston University, 2012. https://hdl.handle.net/2144/32047.

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Thesis (Ph.D.)--Boston University<br>PLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request. If you are the author or principal advisor of this work and would like to request open access for it, please contact us at open-help@bu.edu. Thank you.<br>Estimation of exposure-specific risks (ESRs) using estimates of the overall risk and relative risk of disease given exposure has been performed in previous studies, but the performance of such an estimator ha
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Vixner, Linda, Lena B. Mårtensson, Elisabet Stener-Victorin, and Erica Schytt. "Manual and electroacupuncture for labour pain : study design of a longitudinal randomized controlled trial." Högskolan Dalarna, Medicinsk vetenskap, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:du-10073.

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Introduction. Results from previous studies on acupuncture for labour pain are contradictory and lack important information on methodology. However, studies indicate that acupuncture has a positive effect on women's experiences of labour pain. The aim of the present study was to evaluate the efficacy of two different acupuncture stimulations, manual or electrical stimulation, compared with standard care in the relief of labour pain as the primary outcome. This paper will present in-depth information on the design of the study, following the CONSORT and STRICTA recommendations. Methods. The stu
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Ware, Lorraine, Tatsuki Koyama, Dean Billheimer, et al. "Advancing donor management research: design and implementation of a large, randomized, placebo-controlled trial." BioMed Central, 2011. http://hdl.handle.net/10150/610331.

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BACKGROUND:Given the persistent shortage of organs for transplantation, new donor management strategies to improve both organ utilization and quality of procured organs are needed. Current management protocols for the care of the deceased donor before organ procurement are based on physiological rationale, experiential reasoning, and retrospective studies without rigorous testing. Although many factors contribute to the lack of controlled clinical trials in donor management, a major factor is the unique challenges posed by research in the brain-dead organ donor.METHODS AND RESULTS:This article
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Dunn, Rose. "Using Pre-Session Mindfulness to Improve Session Presence and Effectiveness: A Randomized-Controlled Trial." Thesis, University of North Texas, 2016. https://digital.library.unt.edu/ark:/67531/metadc862760/.

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While a significant amount of research illustrates the overall positive effects of therapists' general use of mindfulness, very few studies have addressed whether therapists' use of mindfulness translates to improved psychotherapy outcomes. The present study utilized a randomized-controlled design to test whether a brief mindfulness training program and pre-session mindfulness practice could have a positive impact on therapy; in particular, we hypothesized that mindfulness training and practice would improve ratings on therapeutic presence as rated by clients and therapists and session effect
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Orr, Serena. "The Pharmacologic Prophylaxis of Pediatric Migraine: A Systematic Review, Survey and Design of a Randomized Controlled Trial." Thesis, Université d'Ottawa / University of Ottawa, 2016. http://hdl.handle.net/10393/35109.

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Objectives: 1) To describe the state of the evidence for interventions in pediatric migraine, 2) to survey experts regarding non-inferiority margins in migraine research and 3) to design a clinical trial in this area of research. Methods: A systematic review was carried out to identify randomized, placebo-controlled trials of pharmaceutical and nutraceutical interventions used to prevent migraine in children and adolescents, using Cochrane methods. Secondly, neurologists with expertise in Headache Medicine were invited to participate in a survey regarding their opinions on non-inferiority m
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Ben, Rahal Gahda B. S. [Verfasser], and Ralf-Joachim [Akademischer Betreuer] Kohal. "Evaluation of two different implant designs: preliminary results of a randomized controlled equivalence trial." Freiburg : Universität, 2020. http://d-nb.info/1221061429/34.

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Bell, Melanie L., Amy L. Whitehead, and Steven A. Julious. "Guidance for using pilot studies to inform the design of intervention trials with continuous outcomes." DOVE MEDICAL PRESS LTD, 2018. http://hdl.handle.net/10150/627081.

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Background: A pilot study can be an important step in the assessment of an intervention by providing information to design the future definitive trial. Pilot studies can be used to estimate the recruitment and retention rates and population variance and to provide preliminary evidence of efficacy potential. However, estimation is poor because pilot studies are small, so sensitivity analyses for the main trial's sample size calculations should be undertaken. Methods: We demonstrate how to carry out easy-to-perform sensitivity analysis for designing trials based on pilot data using an example. F
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Dakin, Helen A. "Economic evaluation of factorial randomised controlled trials." Thesis, University of Oxford, 2015. http://ora.ox.ac.uk/objects/uuid:77eda1f6-dd8c-439a-8871-75fd57a4c7f5.

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Factorial randomised controlled trials (RCTs) evaluate two or more interventions simultaneously, enabling assessment of interactions between treatments. This thesis presents literature reviews, methodological reviews, simulation studies and applied case studies that explore methods for assessing cost-effectiveness based on factorial RCTs. My systematic review suggests that factorial RCTs account for around 3% of trial-based economic evaluations, although there is currently no guidance or methodological work indicating the most appropriate methods. Around 40% of published studies assumed no int
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Dong, Ranran. "Stepped Wedge Cluster Randomized Controlled Trials for Three-Level Data: Design and Evaluation." The Ohio State University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=osu1514492341281384.

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Dunning, Andrew J. "Aspects of matching and power in group randomized trials /." Thesis, Connect to this title online; UW restricted, 2001. http://hdl.handle.net/1773/9592.

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Steiner-Boeker, Sabine. "Novel P2Y12 Receptor Antagonists - Prasugrel and Ticagrelor. Systematic Review, Indirect Comparison to Clopidogrel in Cardiovascular Disease, Design of a Randomized Controlled Trial." Thesis, Université d'Ottawa / University of Ottawa, 2011. http://hdl.handle.net/10393/20176.

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Antiplatelet therapy with clopidogrel is widely used in patients with coronary artery disease, but the recent development of the new P2Y12 receptor antagonists prasugrel and ticagrelor will increase treatment options. An overview of systematic reviews was performed to summarize available evidence on clopidogrel. Current data on prasugrel and ticagrelor were identified by a systematic review and used for an indirect treatment comparison (ITC) of the drugs against each other and versus placebo in the absence of head-to-head clinical trials. Adjusted indirect comparison according to Bucher, Bayes
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14

You, Zhiying. "Power and sample size of cluster randomized trials." Thesis, Birmingham, Ala. : University of Alabama at Birmingham, 2008. https://www.mhsl.uab.edu/dt/2009r/you.pdf.

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Manjang, Buba. "Investigating effectiveness of behavioural change intervention in improving mothers weaning food handling practices : design of a cluster randomized controlled trial in rural Gambia." Thesis, University of Birmingham, 2017. http://etheses.bham.ac.uk//id/eprint/7471/.

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Objectives: To evaluate the effectiveness of a theory-based and culturally adapted community level behaviour change intervention to improve weaning-food preparation and handling in rural Gambia. Methods: (1) A systematic review of the literature on weaning-food hygiene interventions. (2) Mixed method formative research to identify critical control points (CCP) and motivational factors for mothers‟ behaviour on weaning-food, (3) Formulation of the weaning-food hygiene intervention including performing arts. (4) Implementation and evaluation of the intervention with a cluster randomized controll
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Walker, Jane. "Evaluation of a complex intervention for depression in patients with lung cancer : the design, execution and results of a randomised controlled trial." Thesis, University of Edinburgh, 2014. http://hdl.handle.net/1842/9560.

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The aim of this thesis was to develop and evaluate a complex intervention for major depression in patients with lung cancer. Major depression is a leading cause of disease burden worldwide and is particularly important in patients with lung cancer, not only because it is common in this poor prognosis cancer group but also because it substantially reduces the quality of the often short period of time that patients have left to live. The thesis describes a systematic review of the relevant research literature, the development of a complex intervention and a multi-centre randomised controlled tri
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Russell, Trevor G. "Establishing the efficacy of telemedicine as a clinical tool for physiotherapists : from systems design to randomised controlled trial /." [St. Lucia, Qld.], 2004. http://adt.library.uq.edu.au/public/adt-QU20040608.114117/index.html.

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18

Hedman, Katarina. "Pooling Data from Similar Randomized Clinical Trials Comparing Latanoprost with Timolol; Medical Results and Statistical Aspects." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3392.

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19

Walters, Kimberly Ann. "The Use Of Post-Intervention Data From Waitlist Controls To Improve Estimation Of Treatment Effect In Longitudinal Randomized Controlled Trials." The Ohio State University, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=osu1218445774.

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20

Kotb, Ahmed. "The Impact of Telemedicine in the Rehabilitation of Patients with Heart Diseases." Thèse, Université d'Ottawa / University of Ottawa, 2014. http://hdl.handle.net/10393/30490.

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The potential that telemedicine interventions may have in effectively delivering remote specialized cardiovascular care to large numbers of patients with heart diseases has recently come under question. In the first phase of this thesis, a systematic review and meta-analysis was conducted to compare the impact of a basic form of telemedicine that is regular patient follow-up by telephone, with usual care for individuals with coronary artery disease following their discharge. In the second phase of this thesis, a network meta-analysis, using Bayesian methods for multiple treatment comparisons,
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21

Newlands, Rumana. "Design and outcomes of a feasibility randomised controlled trial of lifestyle weight loss intervention in women treated for breast cancer." Thesis, University of Aberdeen, 2016. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=231668.

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Introduction: Breast cancer is the most frequent cancer among women worldwide. Breast cancer treatments and treatment-related factors (type, dose, duration, and side-effects) have been found to be associated with weight gain in women. Overweight and obesity, in breast cancer survivors, is associated with increased risk of breast cancer-specific and all-cause mortality. Prognosis may be improved by maintaining a healthy weight but research in weight management in women treated for breast cancer is relatively limited. Aim: To design a weight loss trial for women treated for breast cancer and to
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22

Hartinger, S. M., Claudio F. Lanata, J. Hattendorf, et al. "A community randomised controlled trial evaluating a home-based environmental intervention package of improved stoves, solar water disinfection and kitchen sinks in rural Peru: Rationale, trial design and baseline findings." Elsevier B.V, 2015. http://hdl.handle.net/10757/347070.

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clanata@iin.sld.pe<br>Introduction: Pneumonia and diarrhoea are leading causes of death in children. There is a need to develop effective interventions. Objective: We present the design and baseline findings of a community-randomised controlled trial in rural Peru to evaluate the health impact of an Integrated Home-based Intervention Package in children aged 6 to 35 months. Methods: We randomised 51 communities. The intervention was developed through a community-participatory approach prior to the trial. They comprised the construction of improved stoves and kitchen sinks, the promotion of han
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Pettersson, Anna. "Diet and Gastrointestinal Symptoms in Patients with Prostate Cancer Treated with Radiotherapy." Doctoral thesis, Uppsala universitet, Enheten för onkologi, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-215410.

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Objective The main objective of this thesis was to explore the effects of diet on gastrointestinal symptoms in prostate cancer patients treated with local curative radiotherapy, by evaluating dietary intake prior to treatment (Study I), the psychometric properties of a new questionnaire on patient-reported gastrointestinal side effects (Study II), and the effect of a dietary intervention on acute and long-term gastrointestinal symptoms up to 2 years after radiotherapy completion (Study III-IV). Methods A total of 130 men with localized prostate cancer referred to dose-escalated radiotherapy (E
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Pisinthpunth, C. "A Guideline for Environmental Games (GEG) and a randomized controlled evaluation of a game to increase environmental knowledge related to human population growth." Thesis, Coventry University, 2015. http://curve.coventry.ac.uk/open/items/ab227155-e0c9-4389-a76c-33b9f8283fcf/1.

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People often have very little knowledge about the impact of unsustainable human population growth on the environment and social well-being especially in developing countries. Therefore, an efficient method should be explored in order to educate, and if possible, to convince the members of the public to realize the environmental and social problems caused by the unsustainable population growth. Digital Game-Based Learning (DGBL) has been highlighted by some studies as an innovative tool for learning enhancement. While only a handful of studies have scientifically evaluated the impact of DGBL on
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Picchiottino, Mathieu. "Effets des manipulations articulaires sur les marqueurs de l'activité du système nerveux autonome The acute effects of joint manipulative techniques on markers of autonomic nervous system activity: a systematic review and meta-analysis of randomized sham-controlled trials The effect of a single spinal manipulation on cardiovascular autonomic activity and the relationship to pressure pain threshold: a randomized, cross-over, sham-controlled trial What is the effect of spinal manipulation on the pressure pain threshold in young asymptomatic subjects? A randomized placebo-controlled trial, with a cross-over design." Thesis, université Paris-Saclay, 2020. http://www.theses.fr/2020UPASS103.

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L’utilisation des manipulations articulaires dans la prise en charge de certains troubles musculosquelettiques est ancienne, répandue et soutenue par la littérature scientifique. Cependant, les mécanismes d’action des différentes techniques de manipulation sont mal compris. Le potentiel effet des manipulations articulaires sur l’activité autonome est une composante fondamentale de théories relatives à leurs mécanismes d’action. Une de ces théories propose l’activation, par les manipulations articulaires, du système inhibiteur descendant de la douleur via la stimulation de la substance grise pé
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Teixeira, Marcus Zulian. "Ensaio clínico quali-quantitativo para avaliar a eficácia e a efetividade do tratamento homeopático individualizado na rinite alérgica perene." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/5/5159/tde-10062009-102220/.

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INTRODUÇÃO: A rinite alérgica é uma condição clínica comum que apresenta sintomas diversos num significante número de pacientes, deteriorando a qualidade de vida daqueles refratários aos tratamentos usuais (anti-histamínicos e corticosteróides nasais tópicos). Apresentando princípios curativos similares, a imunoterapia sublingual e a homeopatia podem reduzir os sintomas e a necessidade de medicamentos na rinite alérgica, embora a eficácia e a efetividade de ambas terapêuticas não sejam ainda suficientemente conhecidas. OBJETIVOS: O objetivo deste estudo foi avaliar a efetividade clínica do tra
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Laubender, Rüdiger Paul [Verfasser]. "Estimation of a joint distribution with two normally distributed treatment responses as marginals generated in a randomized controlled trial based on the parallel-group design by using a normally distributed covariate. / Rüdiger Paul Laubender." München : Verlag Dr. Hut, 2014. http://d-nb.info/1063222001/34.

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Thompson, Thomas Paul. "The design and multi-method evaluation of a pilot pragmatic randomised controlled trial of an exercise assisted reduction of smoking intervention among socioeconomically disadvantaged smokers." Thesis, University of Exeter, 2014. http://hdl.handle.net/10871/18607.

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Background: Smoking contributes to health inequalities and there is a need to focus interventions on the disadvantaged. Abrupt quitting is widely advocated, but assisted ‘reduction’ may be an option for those not ready to quit. Physical activity acutely reduces cigarette cravings and withdrawal symptoms, and may increase long-term cessation and reduce weight gain. This thesis reports on the multi-method evaluation of an intervention delivered by Health Trainers (HTs) and a pilot randomised controlled trial of the Exercise Assisted Reduction then Stop (EARS) intervention for disadvantaged smoke
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Soler-Font, Mercè 1991. "Prevention and management of musculoskeletal pain at work in nursing staff : Design, implementation and evaluation of a multifaceted intervention in the workplace." Doctoral thesis, TDX (Tesis Doctorals en Xarxa), 2021. http://hdl.handle.net/10803/672387.

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Objectiu: Dissenyar, implementar i avaluar una intervenció multifacètica en el lloc de treball per prevenir i gestionar el dolor musculoesquelètic (DME). Mètodes: Es va dissenyar, implementar i avaluar (efectivitat, procés i cost-efectivitat) un assaig controlat aleatoritzat per clústers d'un any. La intervenció va incloure ergonomia participativa, promoció de la salut i gestió de casos. Resultats: Als 12 mesos, el grup d’intervenció va mostrar una disminució estadísticament significativa del risc de dolor d’espatlles, cervical i dorsal en comparació amb el control. No es va trobar cap efect
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Möller, Hans. "Isthmic spondylolisthesis in adults : a randomized controlled trial /." Stockholm, 1999. http://diss.kib.ki.se/1999/91-628-3834-2/.

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Doiron, Jason. "Prevention of pathological gambling a randomized controlled trial /." access full-text online access from Digital Dissertation Consortium, 2005. http://libweb.cityu.edu.hk/cgi-bin/er/db/ddcdiss.pl?NR25497.

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Wong, Ho-hang Anthony. "A randomized controlled trial of home tooth-whitening products." Click to view the E-thesis via HKUTO, 2004. http://sunzi.lib.hku.hk/hkuto/record/B3195439X.

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Bukusi, Elizabeth Anne. "Bacterial vaginosis : a randomized controlled trial to prevent recurrence /." Thesis, Connect to this title online; UW restricted, 2006. http://hdl.handle.net/1773/10880.

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Wong, Ho-hang Anthony, and 黃浩行. "A randomized controlled trial of home tooth-whitening products." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2004. http://hub.hku.hk/bib/B3195439X.

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Holmlund, Thorbjörn. "Evaluation of surgical methods for sleep apnea and snoring." Doctoral thesis, Umeå universitet, Institutionen för klinisk vetenskap, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-118944.

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Background: Snoring and obstructive sleep apnea (OSA) are both common disorders with a number of negative health effects. The safety and efficacy of treating snoring and OSA surgically have been questioned and there has been a lack of studies in the field. Aims: 1) To investigate the frequency of serious complications, including death, after surgery for the treatment of snoring and sleep apnea; 2) to evaluate the effect on daytime sleepiness after radiofrequency surgery of the soft palate in snoring men with mild or no OSA; 3) to evaluate the effect of tonsillectomy on sleep apnea in adults wi
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Baumueller, Eva. "Electromyogram-Biofeedback in Patients with Fibromyalgia A Randomized Controlled Trial." Diss., lmu, 2009. http://nbn-resolving.de/urn:nbn:de:bvb:19-109423.

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Chong, Shing-kan Patrick. "A randomized controlled trial for exercise prescription in general practice." Click to view the E-thesis via HKUTO, 2003. http://sunzi.lib.hku.hk/hkuto/record/B31970977.

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Hoskins, Eric William. "Edmonson-Zagreb measles vaccine : randomized controlled clinical trial in Sudan." Thesis, University of Oxford, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.386576.

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Chong, Shing-kan Patrick, and 莊承謹. "A randomized controlled trial for exercise prescription in general practice." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2003. http://hub.hku.hk/bib/B31970977.

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Hay, Jacqueline. "Physical activity intensity and visceral adiposity: a randomized controlled trial." American Medical Association, 2012. http://hdl.handle.net/1993/16315.

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Background: Physical activity (PA) reduces visceral adipose tissue (VAT) in adults; however, the dose to reduce VAT in youth is unclear. Objective: To examine whether high intensity PA preferentially reduces waist circumference (WC) and VAT compared to lower intensity PA. Design: Randomized controlled trial. Participants: Youth were 13-18yrs, overweight, with one additional risk factor for type 2 diabetes (T2DM). Intervention: 6-months, exercising 3 times/week at a high intensity (70-85% of Heart Rate Reserve HRR), or low intensity (40-55% HRR). Primary outcome: VAT (cm2) measured by MR
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Castelein, Stynke. "Guided peer support groups for psychosis a randomized controlled trial /." [S.l. : [Groningen : s.n.] ; University of Groningen] [Host], 2009. http://irs.ub.rug.nl/ppn/.

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Lee, Eric B. "Telepsychotherapy for the Treatment of Trichotillomania: A Randomized Controlled Trial." DigitalCommons@USU, 2018. https://digitalcommons.usu.edu/etd/7012.

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Trichotillomania is defined as recurrent pulling of one’s hair that results in distress and negative effects on general functioning and quality of life. Estimates of trichotillomania lifetime prevalence generally range from approximately 1% to 3% and it is likely as common as disorders such as obsessive-compulsive disorder and agoraphobia. Yet, quality treatment for trichotillomania is often difficult to find as many mental health professionals are uninformed about the disorder and its treatment. Moreover, mental health services in general are inaccessible to many with estimates suggesting tha
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Bockrath, Margaret Feuille. "Mindfulness meditation training for spiritual struggles: A randomized controlled trial." Bowling Green State University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1445504635.

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Flynn, Terry Nicholas. "Design and analysis of randomised controlled trials : economic aspects of cluster randomisation." Thesis, University of Bristol, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.393952.

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Hill, Ryan M. "Open Trial and Pilot Randomized Controlled Trial of a Novel Program to Reduce Perceived Burdensomeness." FIU Digital Commons, 2015. http://digitalcommons.fiu.edu/etd/2243.

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To date, suicide prevention programs for adolescents have not demonstrated sustained reductions in suicide-related behaviors and further program development is called for, particularly for the prevention of non-clinical suicide risk. This research utilizes the Interpersonal-Psychological Theory of Suicide in the development of the LEAP Program, a novel, web-based suicide prevention program targeting reductions in cognitions of perceived burdensomeness. An open trial of the program was conducted to examine the feasibility of the study protocol, generate feedback regarding the LEAP program modul
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Buttner, Melissa Mercedes. "Efficacy of Yoga for Depressed Postpartum Women: a Randomized Controlled Trial." Diss., University of Iowa, 2013. https://ir.uiowa.edu/etd/4825.

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Postpartum depression (PPD) is a significant public health issue. Up to 20% of women are affected by depression following childbirth. PPD is associated with anxiety, poor adjustment and health-related quality of life (HRQOL), and may lead to a woman's personal suffering, conflict with family members (especially in the relationship with partner) and developmental delays in children. Given the high prevalence of PPD and deleterious effects on both women and their families, adequate treatment is critical. While existing PPD t
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Baik, Kyoung deok. "Evaluating Acceptance and Commitment Therapy for Insomnia: A Randomized Controlled Trial." Bowling Green State University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1435680293.

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Mullett, Margaret. "Conducting a randomised experiment in eight English prisons : a participant observation study of testing the Sycamore Tree Programme." Thesis, University of Cambridge, 2016. https://www.repository.cam.ac.uk/handle/1810/275047.

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This dissertation is a participant observer’s account of implementing a multisite, randomised controlled trial within Her Majesty’s Prison Service. It adds to a scarce literature detailing the steps involved in implementing experiments in custodial settings by providing a candid account of the route from planning to successful implementation. The randomised controlled trial was designed to evaluate the effectiveness of the Sycamore Tree Programme. This programme’s goal is to teach prisoners the wider harm of crime and includes a face-to-face meeting between a victim of crime and the participat
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Gebreselassie, Hailemichael. "Iron supplementation and malaria infection : results of a randomized controlled field trial." Thesis, McGill University, 1996. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=42040.

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Iron deficiency anaemia is associated with several ill-health effects. Its treatment and/or control with iron preparations in malaria endemic areas has, however, been implicated to increase host susceptibility to malaria infection. Scientific evidence accumulated to date remains equivocal about the presence of this increased susceptibility. The present work was planned to address the existing controversy by assessing the effect of oral iron supplementation on host susceptibility to malaria infection.<br>A randomized, double-blind, placebo-controlled field trial of oral ferrous sulphate supplem
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Gebreselassie, Hailemichael. "Iron supplementation and malaria infection, results of a randomized controlled field trial." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/NQ29944.pdf.

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