To see the other types of publications on this topic, follow the link: Rapid application development; Concurrent.
Dissertations / Theses on the topic 'Rapid application development; Concurrent'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the top 50 dissertations / theses for your research on the topic 'Rapid application development; Concurrent.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.
1
Marshall, Cameron Alexander. "An investigation into how high quality, low risk, manufacturing systems can be developed within short development lead times." Thesis, University of Sunderland, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.365409.
Full text
2
Munguía, Valenzuela Francisco Javier. "RMADS: development of a concurrent Rapid Manufacturing Advice System." Doctoral thesis, Universitat Politècnica de Catalunya, 2009. http://hdl.handle.net/10803/6852.
Full textAbstract:
La intenció d'aquest projecte de recerca és anar més enllà de l' aconseguit pels sistemes existents de selecció i comparació de processos de Prototipat Ràpid, mitjançant la introducció d'una nova metodologia que tingui com a únic fi la 'Fabricació Final' de components. El sistema desenvolupat incorpora algunes de les eines més recents del camp de Intel·ligència Artificial, de manera que sigui possible aconseguir una metodologia concurrent que inclogui:· Sistemes experts, que s'executen durant el procés de presa de decisions amb alternatives múltiples. Els sistemes experts utilitzen típicament estructures del tipus: IF-THEN-ELSE o CASE, de manera que les opcions puguin ser 'cribrades' especialment durant les primeres etapes de la selecció.
· Lògica difusa per a la presa de decisions. Normalment en l'àmbit de la fabricació, alguns termes lingüístics o paràmetres de tipus qualitatiu són utilitzats per definir estats o propietats. Per exemple és comú trobar termes qualitatius com ara: 'bones propietats mecàniques "o" alta taxa d'absorbència', en lloc de xifres i números puntuals. Per tant és necessari comptar amb un mètode per traduir i gestionar aquesta informació. La lògica difusa ha estat adoptada com a mitjà per traduir termes d'ordre qualitatiu a informació quantitativa de manera que a partir d'aquestes dades es pugui construir un sistema de classificació i rànquing de processos.
· Presa de decisions Multi-criteri, agrupació (sumatòria) i classificació. Durant la investigació es van provar diferents mètodes per a la classificació d'alternatives i selecció final a partir de vectors d'ordre quantitatiu amb pesos ponderats. Per a aquesta finalitat es va adoptar la metodologia proposada per Lan et al. (2005) el qual es descriu en el capítol 5 d'aquest treball.
· Xarxes Neuronals Artificials. Aquestes han estat aplicades per a la modelització i simulació d'alguns processos de Fabricació Ràpida prèviament seleccionats. Per exemple, el procés de Sinteritzat Selectiu Làser es va aconseguir modelar utilitzant Xarxes Neuronals amb un algorisme de "backpropagation", prenent com a informació base, les dades proporcionades pel software propietari de l'equip. Aquesta xarxa neuronal simula una màquina de sinteritzat làser model DTM Vanguard, disponible a la FundacioCIM-UPC a Barcelona. D'altra banda el procés de Fusió selectiva per làser ha estat modelat també mitjançant Xarxes Neuronals a partir de l'equip Concep Laser M2, disponible al laboratori d'Enginyeria mecànica de la Universitat Catòlica de Lovaina, Bèlgica. Els models extrets d'aquestes simulacions mostren una estimació del temps total de fabricació menor al 10% la qual cosa representa una millora substancial respecte a mètodes d'estimació paramètrics.
· Finalment s'ha utilitzat la tècnica de bases de dades relacionals per a la gestió i emmagatzematge d'informació sobre materials. Aquestes bases de dades han estat creades en Ms Access, que proporciona la facilitat d'accés, filtrat, graficació i presentació de la informació requerida. Aquesta informació pot ser extreta automàticament mitjançant trucades ODBC, executades des de l'entorn Matlab.
Per a il·lustrar el funcionament de les eines descrites en una forma integrada, s'ha optat per desenvolupar una aplicació pilot en Matlab, utilitzant alguns "Tool boxes" especialitzats com: Lògica difusa, Xarxes neuronals, Estadística, Utilitats de graficació, Creació d'interfície d'usuari (GUI), Bases de dades. El resultat d'aquesta integració és una aplicació pilot anomenada RMADS (Rapid Manufacturing Advice System), el qual compta amb una interfície gràfica d'usuari que es divideix en tres mòduls:
· Requeriments generals de disseny. Aquest mòdul analitza els paràmetres usualment definits en les especificacions inicials de Producte, per exemple: tipus de material, toleràncies, acabat superficial, complexitat geomètrica, etc.
· Mòdul de costos. Aquest mòdul utilitza paràmetres d'entrada prèviament introduïts com: volum de peça, mida de lot i dimensions totals, per a realitzar càlculs mitjançant mètodes paramètrics i models basats en xarxes neuronals. El resultat és una estimació del cost per peça i també el cost estès per volums grans.
· Selecció de materials. Aquest mòdul mostra la natura iterativa del procés de selecció de materials, a través de criteris de "filtratge" o selecció, de manera que a cada iteració el nombre d'opcions sigui limitat a un nombre raonable d'alternatives.
The intention of this research is to go beyond currently available systems for the assessment and selection of Rapid Prototyping processes, hence introducing a new methodology devoted to 'Manufacturing' applications. Specifically the system would include a number of state of the art artificial Intelligence techniques to comprise a fully concurrent methodology, namely:
· Expert systems are included to aid in the decision making process with multiple alternatives. Expert systems typically use If-Then-Else or CASE structures so that the available options can be screened specially during the first selection stages.
· Fuzzy logic for decision making. Usually in manufacturing, linguistic terms or qualitative parameters are used to define states of properties. For instance it is common to find terms such as 'Good mechanical properties' or 'High absortivity rates' therefore it is necessary to have a method to translate and manage such information. Fuzzy logic has been adopted as a means to translate qualitative terms to quantitative information.
· Multi-criteria decision making, aggregation and ranking. Different methods for selecting and ranking alternatives were tested which allows the integration of quantitative vectors with weighting factors that reflect the user preferences. For this purpose the method proposed by Lan et al. (2005) has been adopted as discussed in Chapter 5.
· Artificial Neural Networks (ANNs) are being applied for the modelling and simulation of a number of Rapid Manufacturing Methods. Selective Laser Sintering has been modelled using a back propagation algorithm ANN taking as a basis the information provided by the machine software. The ANN simulates a DTM Vanguard SLS machine available at Fundacio CIM-UPC, Barcelona, while the Selective Laser Melting has been modelled with the parameters and settings used by the Concept Laser M2 machine available at the Mechanical Engineering Lab of the Catholic University of Leuven, Belgium. The extracted models exhibit a build-time prediction error rate lower than 10%, which is a significant improvement compared to conventional parametric methods.
· Finally, relational databases have been applied for storing and handling materials information. These databases have been stored as Ms Access data which provides the ease to access, filter, screen and plot the required information. This data can be automatically called and extracted by means of an ODBC call deployed within the Matlab environment.
In order to illustrate the functionality of the previous tools put together, a pilot application was designed in Matlab, making use of a number of specialized toolboxes namely: Fuzzy logic, Neural Network, Statistics, Plotting utilities, GUI builder, Database.
The result is a prototype system with a graphic user interface divided in three modules:
· General design requirements: which deals with those parameters usually defined in the product PDS, for instance: material type, tolerances, surface roughness, geometrical complexity, etc.
· Costing module: which makes use of parametric cost estimation and ANN-based models to perform the calculation of cost per part, and for low volumes
· Materials selection: Shows the iterative nature of materials selection through screening steps so that the range of suitable options is limited.
3
Lettice, Fiona E. "Concurrent engineering : a team-based approach to rapid implementation." Thesis, Cranfield University, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.283251.
Full text
4
Lomax, Franklin Delano. "Application of Concurrent Development Practices to Petrochemical Equipment Design." Diss., Virginia Tech, 2001. http://hdl.handle.net/10919/26587.
Full textAbstract:
Principles of concurrent development are applied to the design of a small-scale device for converting natural gas or liquefied petroleum gas into hydrogen. The small hydrogen generator is intended for serial production for application in the production of industrial hydrogen, fueling stationary fuel cell power systems and refueling hydrogen-fueled fuel cell electric vehicles. The concurrent development process is contrasted with the traditional, linear development process for petrochemical systems and equipment, and the design is benchmarked against existing small hydrogen generators as well as industrial hydrogen production apparatus. A novel system and hardware design are described, and a single cycle of concurrent development is applied in the areas of catalyst development, thermodynamic optimization, and reactor modeling and design. The impact of applying concurrent development techniques is assessed through economic modeling, and directions for future development work are identified.Ph. D.
5
Barrow, Patrick D. M. "Investigating stakeholder evaluation within rapid application development." Thesis, University of East Anglia, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.323267.
Full text
6
Hernadez, Frank. "MobiMed: Framework for Rapid Application Development of Medical Mobile Apps." FIU Digital Commons, 2013. http://digitalcommons.fiu.edu/etd/957.
Full textAbstract:
In the medical field images obtained from high definition cameras and other medical imaging systems are an integral part of medical diagnosis. The analysis of these images are usually performed by the physicians who sometimes need to spend long hours reviewing the images before they are able to come up with a diagnosis and then decide on the course of action. In this dissertation we present a framework for a computer-aided analysis of medical imagery via the use of an expert system. While this problem has been discussed before, we will consider a system based on mobile devices.
Since the release of the iPhone on April 2003, the popularity of mobile devices has increased rapidly and our lives have become more reliant on them. This popularity and the ease of development of mobile applications has now made it possible to perform on these devices many of the image analyses that previously required a personal computer. All of this has opened the door to a whole new set of possibilities and freed the physicians from their reliance on their desktop machines.
The approach proposed in this dissertation aims to capitalize on these new found opportunities by providing a framework for analysis of medical images that physicians can utilize from their mobile devices thus remove their reliance on desktop computers. We also provide an expert system to aid in the analysis and advice on the selection of medical procedure. Finally, we also allow for other mobile applications to be developed by providing a generic mobile application development framework that allows for access of other applications into the mobile domain.
In this dissertation we outline our work leading towards development of the proposed methodology and the remaining work needed to find a solution to the problem. In order to make this difficult problem tractable, we divide the problem into three parts: the development user interface modeling language and tooling, the creation of a game development modeling language and tooling, and the development of a generic mobile application framework. In order to make this problem more manageable, we will narrow down the initial scope to the hair transplant, and glaucoma domains.
7
Truscott, M., G. J. Booysen, and Beer D. J. De. "Rapid prototyping and manufacturing in medical product development." Interim : Interdisciplinary Journal, Vol 8, Issue 2: Central University of Technology Free State Bloemfontein, 2009. http://hdl.handle.net/11462/373.
Full textAbstract:
Published ArticleRP and recently RM have been key factors in the development of the manufacturing industry in assisting in the development of new products. Fortunately, the application of these technologies has been realised in the medical industry. Surgeons all over the world use physical models created from CT or MRI data using some sort of additive manufacturing. The fabrication of these models has exploded into a popular research area combining engineering, material and medical expertise. Long-term growth in the additive fabrication industry will come from designs that are difficult, time-consuming, costly, or impossible to produce using standard techniques. Growth will occur with advances in current additive processes which are coupled with breakthroughs in new materials. The applications of RP and RM are as diverse as the medical issues that arise. RM of custom design medical prostheses proves to be economically viable solution, not only because it is faster to produce but it gives the designer freedom of creation too. The paper discusses some interesting medical case studies.
8
Albrecht, Conan Carl. "Programming framework supporting the rapid application development of highly-interactive, collaborative applications." Diss., The University of Arizona, 2000. http://hdl.handle.net/10150/558708.
Full textAbstract:
Business team collaboration in the future will increasingly take place in an
environment where everything is potentially distributed. Traditional group support systems
have been LAN-based and have not ported easily to distributed, Internet-based products.
Rather, distributed group support systems require new architectures if they are to support the
same type of real-time, high-collaboration environments that traditional systems have.
This dissertation describes the development of a server architecture and programming
model to support the rapid application development of real-time, distributed, and
collaborative applications. Since the efficiency, robustness, and scalability of these
applications are handled by the server, complex applications can be developed in very short
production cycles.
Background literature presented in the dissertation includes a taxonomy of distributed
networking and data sharing methods, models of dialog independence, and messaging
methods. Many different prototype and real systems are presented, analyzed, and compared
with the Collaborative Server in this dissertation. The Systems Development methodology
is applied to this research domain.
A prototype system-the “Collaborative Server”-is developed, including a unique data
persistence and replication scheme based upon a central Property object. Properties are
created in hierarchical trees to form the “scaffolding” for collaborative applications. Each
Property governs a single value, or datum, and controls the access, replication, security,
viewing, locking, and persistence of its value. Properties are layered with predefined or
custom child indices.
A new systems development methodology, based upon the Waterfall method but
tailored for the Collaborative Server, is presented. The efficiency and effectiveness of this
methodology is analyzed using a simulated example and two case studies.
The research contribution of this dissertation is the Collaborative Server. The basis
of this server is the Property concept, including the methodology changes it effects, the
efficiencies and application stability it produces, and the specialized messaging system it
allows. Required programmer knowledge is significantly reduced when applications are built
upon the Collaborative Server. In addition, the presented examples and case studies show
significant decreases in code size and in time-to-market for their respective applications.
9
Clark, Lucille Charlotte. "Information engineering and the Information Engineering Facility verus rapid application development and FOCUS." Thesis, Monterey, California. Naval Postgraduate School, 1992. http://hdl.handle.net/10945/23703.
Full text
10
Owusu, Dompreh Francis. "Application of Rapid Manufacturing Technologies to Integrated Product Development inClinics and Medical Manufacturing Industries." Youngstown State University / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=ysu1389697786.
Full text
11
Krüger, Christina. "The state scale of dissociation : development, psychometric validation, and application in a study of concurrent electro-encephalographic correlates." Thesis, University of Warwick, 1998. http://wrap.warwick.ac.uk/38291/.
Full textAbstract:
The distinction between state and trait dissociation informed the development and psychometric validation of the State Scale of Dissociation (SSD) and the study of concurrent electro-encephalographic (EEG) correlates of experimentally induced dissociative states. Existing scales measure trait dissociation. The need for a state scale was addressed by the development and testing of a present-state, self-report measure. Fifty-eight preliminary items were sorted into 7 subscales: derealisation, depersonalisation, identity confusion, identity alteration, conversion, amnesia, and hypermnesia. A revised 56-item SSD was administered with other psychiatric scales (DES, BDI, BAI, SCI-PANSS) to patients with DSM-IV major depressive disorder (n=19), schizophrenia (n=18), alcohol withdrawal (n=20), dissociative disorders (n=10), and controls (n=63). The SSD was demonstrated to be a valid and reliable measure of severity, and changes in severity, of dissociation at the time of its completion. Discriminant validity, content, concurrent, predictive, internal criterionrelated, internal construct, and convergent validities were confirmed statistically by factor analysis, Spearman's rho correlations, confidence intervals, predictive analysis, and parametric and non-parametric comparisons of dependent and independent samples. It showed high internal consistency (Cronbach's alpha = 0.97) and high splithalf reliability (Guttman coefficient = 0.92). The conversion subscale clustered with the other subscales into one general factor on factor analysis and did not support its segregation from dissociative disorders in DSM-IV. State characteristics of dissociation were also examined in 11 patients with complex partial epilepsy. The relationship between concurrent EEG and experimentally induced dissociative states was examined by repeated SSD and baseline DES measurements after spectral analysis of EEG. Canonical analysis demonstrated significant SSD-EEG correlations. Amnesia, identity alteration, and identity confusion correlated with theta, frontal delta, and fast wave EEG activity respectively. The SSD now allows for further investigation of the suggested state continuum of severity and trait continuum of frequency of dissociation in more comprehensive studies of concurrent neurobiological correlates.
12
Kim, Yong Sung. "Development and application of rapid methods for quantification and cultivation of methanogens in biomethane producing fermentors." Thesis, University of the West of Scotland, 2015. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.731776.
Full text
13
Attwater, Iain James Stuart. "Development of an expert system application combining heterogeneous software to form an integrated and concurrent pressure vessel design system." Thesis, University of the West of Scotland, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.259995.
Full text
14
Zhang, Mengmeng. "Application and Development of the CEASIOM-SUMO-EDGE Suite for Rapid AeroData Assessment of Aircraft Flying Qualities." Licentiate thesis, KTH, Aerodynamik, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-34345.
Full textAbstract:
In aircraft design, methods for rapid aerodata assessment and data screening at early stages are instrumentalin reducing development cost and first-time-right processes. New efficient tools for the analysis can easethe transition as the traditional and rigidly structured sequential design process gives way to a concurrentmulti-disciplinary process with the compressed time-span required in the competition for market shares. The CEASIOM-SUMO-EDGE software suite provides a way from initial sizing to stability and control design andassessment, including effects of aero-elasticity. CEASIOM ongoing and further development is driven by user needs, and the thesis reports on fourdifferent design and analysis cases which required enhancement of CEASIOM in several respects. The validation study on the B-747 with its multitude of control surfaces required generalizationof control surface definition and modeling. The clean-sheet design of the TransCruiser Mach 0.97passenger transport required compilation, fusion, and screening of aerodynamics data from many sourcesand in different formats. The DanBus and the asymmetrical twin-prop pusher-puller configuration required translationof geometry representation and development of simple propeller models in the automatic meshgeneration and CFD analysis. The way forward is provided by adoption of common data formats and geometry (and structural, etc.)modeling conventions. To this end the current proprietary XML format should be replaced by a more generalXML system such as CPACS under development at DLR which will be made public in the near future.QC 20110629
SimSAC, 6th EU Framework Programme
15
Chang, Xue Feng. "Development and application of a rapid micro-scale method of lignin content determination in Arabidopsis thaliana accessions." Thesis, University of British Columbia, 2008. http://hdl.handle.net/2429/2448.
Full textAbstract:
Lignin is a major chemical component of plants and the second most abundant natural polymer after cellulose. The concerns and interests of agriculture and industry have stimulated the study of genes governing lignin content in plants in an effort to adapt plants to human purposes. Arabidopsis thaliana provides a convenient model for the study of the genes governing lignin content because of its short growth cycle, small plant size, and small completely sequenced genome. In order to identify the genes controlling lignin content in Arabidopsis accessions using Quantitative Trait Locus (QTL) analysis, a rapid micro-scale method of lignin determination is required.
The acetyl bromide method has been modified to enable the rapid micro-scale determination of lignin content in Arabidopsis. Modifications included the use of a micro-ball mill, adoption of a modified rapid method of extraction, use of an ice-bath to stabilize solutions and reduction in solution volumes. The modified method was shown to be accurate and precise with values in agreement with those determined by the conventional method. The extinction coefficient for Arabidopsis lignin, dissolved using acetyl bromide, was determined to be 23.35 g-iLcm-1. This value is independent of the Arabidopsis accession, environmental growth conditions and is insensitive to syringyl/guaiacyl ratio. The modified acetyl bromide method was shown to be well correlated with the 72% sulfuric acid method once the latter had been corrected for protein contamination and acid-soluble lignin content (R² = 0.988, P < 0.0001).
As determined by the newly developed acetyl bromide method and confirmed by the sulfuric acid method, lignin content in Arabidopsis was found to be a divergent property. Lignin content in Arabidopsis was found to be weekly correlated with growth rate among Arabidopsis accessions (R² = 0.48, P = 0.011). Lignin content was also found to be correlated with plant height among Arabidopsis accessions (R² = 0.491, P < 0.0001).
16
Ozsuer, Erhan. "Development Of A Web-based Manufacturing Application System For Rotational Parts." Master's thesis, METU, 2003. http://etd.lib.metu.edu.tr/upload/1059930/index.pdf.
Full textAbstract:
Developing process plans and part programs rapidly and correctly for CNC machine tools plays a vital role in manufacturing. This study is concerned with the development of a web-enabled virtual design and manufacturing application system for rotational parts. The object oriented methodology is used in the application development. Windows Distributed interNet Application (DNA) architecture which describes a framework of building software technologies in an integrated web and client-server model of computing, is employed in the system. The entire system was modeled with Unified Modeling Language (UML), which is an industry-standard visual modeling notation to express software development architectures. Feature-based design approach, being a practical way of linking the design with manufacturing, is implemented in the rotational part design.
Users have to be registered in order to use the system. With the supplied web site, users can easily register to system. After registration, the user obtains a password and a unique username. Upon the user authentication, the user session starts. A typical user session involves new or past project selection, material selection, part sketching, blank size definition and cutting parameters determination. After all the steps are completed, process plan and part-program, which are required to manufacture the part on Denford Mirac CNC Turning Machine are generated and displayed on the web site and then saved to the database. The application enables the users to see past projects and to generate new process plan and part programs for different cutting parameters. The process plan, part program and the 2D wire frame drawing of the corresponding part are demonstrated on the web site for the chosen projects.
17
Pramudianto, Ferry [Verfasser], Matthias [Akademischer Betreuer] Jarke, and Djamel [Akademischer Betreuer] Sadok. "Rapid application development in the internet of things : a model-based approach / Ferry Pramudianto ; Matthias Jarke, Djamel Sadok." Aachen : Universitätsbibliothek der RWTH Aachen, 2015. http://d-nb.info/1128231697/34.
Full text
18
Osborn, Jonathan Ashley. "Survey of concurrent engineering environments and the application of best practices towards the development of a multiple industry, multiple domain environment." Connect to this title online, 2009.
Find full text
19
Kostioukova, Anastasia. "Alleviating Social Disadvantages of Rapid Economic Growth: A Case for Conditional Cash Transfer (CCT) Application in Old Siam." Scholarship @ Claremont, 2011. http://scholarship.claremont.edu/cmc_theses/148.
Full textAbstract:
The ongoing conflict between Thailand’s red shirt and yellow shirt parties is not purely political. This tension is rooted in a renewed awareness of regional economic and social inequality, a byproduct of rapid economic growth in the past. This thesis seeks to understand the overall consequences of unequal economic development in Thailand, as the rationale for asserting that a conditional cash transfer (CCT) program is an appropriate policy tool for the ongoing reconciliation efforts.
20
Eubanks, Sean Gilrea. "Development and application of a rapid screening technique for the isolation of selernium reduction-deficient mutants of Shewanella putrefaciens." Thesis, Georgia Institute of Technology, 1998. http://hdl.handle.net/1853/25636.
Full text
21
Coole, Timothy John. "An implementation technique for evaluating the application of rapid prototyping into the new product development environment within the utility ceramics industry." Thesis, Staffordshire University, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.265042.
Full text
22
Dang, Quang Khang. "DEVELOPMENT OF A NEW HIGH-STRESS DYNAMIC-LOADING RING-SHEAR APPARATUS AND ITS APPLICATION TO LARGE-SCALE LANDSLIDES." 京都大学 (Kyoto University), 2015. http://hdl.handle.net/2433/202690.
Full text
23
Saiz, Balbastre Sandra. "Development and application of analytical techniques for quality control of biologics and sterile pharmaceutical products." Doctoral thesis, Universitat Autònoma de Barcelona, 2019. http://hdl.handle.net/10803/666802.
Full textAbstract:
El control microbiològic és essencial en la indústria farmacèutica ja que es tracta d’un indicador de la seguretat dels productes. Els mètodes microbiològics utilitzats a les companyies farmacèutiques per analitzar l’ambient del procés de fabricació així com els productes finals estan basats en mètodes de cultiu tradicional. La tecnologia d’aquests mètodes manca de precisió comparada amb les tecnologies més modernes de detecció i identificació microbiològica.
Cada vegada, els requeriments dels controls microbiològics de productes i processos són més estrictes, el que fa que es necessiten mètodes cada vegada més ràpids i precisos. Dintre d’aquest context s’han desenvolupat els mètodes de microbiologia ràpida (RMM) per a la seva implantació a la industria farmacèutica, avalada per les diferents agències reguladores. Les diferents tecnologies en les quals es basen els RMM es coneixen a l’àmbit acadèmic des de fa dècades, no obstant la seva implantació i validació a les indústries farmacèutiques és relativament recent.
La implementació de noves metodologies a l’àmbit farmacèutic està regulada per la normativa de bones practiques de fabricació (BPF), el qual va associat a una adequada validació de les tècniques. Aquesta tesi descriu la implementació de RMM al control microbiològic del procés de fabricació i productes a l’empresa Laboratoris Reig Jofré (RJF). El principal objectiu ha estat dividit en 3 blocs individuals: implementació d’un programa d’identificació microbiana per als aïllats del procés de fabricació i productes; implementació d’un mètode de detecció de microorganismes a l’aire de sales classificades per fabricació asèptica basat en fluorescència induïda per làser i l’ avaluació d’un sistema basat en citometria en fase sòlida per la detecció de microorganismes en productes filtrables.
En general, els RMM implementats han contribuit a obtenir resultats de manera més ràpida, el qual permet mitigar el risc de contaminació en el mateix moment que ha sigut detectat. Aquest projecte assenta les bases per futures aplicacions de RMM en el procés de fabricació farmacèutica.Microbiological testing plays an essential role in the Pharmaceutical Industry as it is an indicator of safety in drug products. The microbiological methods used in the pharmaceutical companies for testing the environment of the manufacturing process as well as the final products are based on traditional culture methods. These methods, although being appropriate for their intended use, rely on century-old technology that lacks accuracy when compared to most up-to-date methodologies for microbial detection and identification. Every time the requirement of microbiological testing of products and processes increases, arising the need of faster and more accurate methods. In this paradigm, rapid microbiological methods (RMM) are developed for their implementation in the pharmaceutical industry encouraged by regulatory agencies. The different technologies in which rapid microbiological methods are based have been known in the academic field for decades, however their implementation and validation in the pharmaceutical industries is relatively recent. Implementation of new methodologies in a pharmaceutical environment ruled under Good Manufacturing Practice (GMP) guidelines needs proper validation of the techniques involved. This thesis describes the implementation of RMM in the microbial monitoring of the pharmaceutical manufacturing process and products in Reig Jofré Laboratories (RJF). The main objective has been divided into three different blocks: implementation of a microbial identification program for the isolates found in the production process and products; implementation of a laser-induced fluorescence system for the detection of airborne microorganisms in cleanrooms for aseptic processing and evaluation of a solid-phase cytometry system for the detection of microorganisms in filterable products. In general, the RMM implemented have contributed to obtain faster results which allows to mitigate contamination risk at the moment it is detected. This projects lays the ground for further applications of RMM in the pharmaceutical manufacturing process.
24
Shah, Niksha Chimanlal Meghji. "Construction and development of bioluminescent Pseudomonas aeruginosa strains : application in biosensors for preservative efficacy testing." Thesis, University of Hertfordshire, 2014. http://hdl.handle.net/2299/15592.
Full textAbstract:
Whole cell biosensors have been extensively used for monitoring toxicity and contamination of compounds in environmental biology and microbial ecology. However, their application in the pharmaceutical and cosmetics industries for preservative efficacy testing (PET) has been limited. According to several pharmacopoeias, preservatives should be tested for microbial activity using traditional viable count techniques; the use of whole cell microbial biosensors potentially provides an alternative, fast, and efficient method. The aim of the study was to construct and develop whole cell microbial biosensors with Pseudomonas aeruginosa ATCC 9027. Constitutive promoters: PlysS, Pspc, Ptat, Plpp and PldcC and the lux-cassette were inserted into plasmid pME4510 and transformed into P. aeruginosa ATCC 9027 cells to produce bioluminescent strains. Plasmids were found to be maintained stably (~50 copies per cell) throughout the growth and death cycle. The novel bioluminescent strains were validated in accordance with the pharmacopoeia using bioluminescence detection and quantification followed by comparison with the traditional plate counting method. The bioluminescent method was found to be accurate, precise and equivalent at a range of 103 – 107 CFU/mL, as compared with plate counting. Recovery of bacterial cells was quantified using bioluminescence; this method proved to be accurate with percentage recoveries between 70-130% for all bioluminescent strains. The method was also more precise (relative standard deviation less than 15%) than the traditional plate counting method or the ATP bioluminescent method. Therefore, the bioluminescent constructs passed/exceeded pharmacopoeial specified criteria for range, limit of detection, accuracy, precision and equivalence. Physiology of the validated bioluminescent strains was studied by assessing the growth and death patterns using constitutive gene expression linked with bacterial replication. Promoter strengths were evaluated at various stages of the growth and death pattern and related to promoter sequences. PlysS, Ptat and Plpp were relatively strong promoters whilst PldcC and Pspc were relatively weak promoters. Relative promoter strength decreased in the order of Plpp>Ptat>PlysS>PldcC>Pspc during the exponential phase whilst Ptat was stronger than Plpp during the stationary phase of growth. Plpp had its highest level of expression during the exponential phase, while Ptat had relatively stable lux expression during the stationary phase. Correlations between relative bioluminescence and CFU at 24 hours were greater than 0.9 indicating a strong relationship for all bioluminescent strains. Reduction in correlation coefficients to approximately 0.6 between relative bioluminescence and CFU and between relative fluorescence and CFU beyond 24 hours indicated that a certain proportion of cells were viable but non-culturable. Tat-pME-lux showed steady bioluminescence compared to CFU count (R>0.9) throughout 28 days of growth. Equivalence analysis showed no significant difference between the bioluminescence and plate count method throughout 28 days of growth for all five bioluminescent strains. Applicability of these novel bioluminescent strains was evaluated for preservative efficacy tests (PET) using bacterial replication and bioluminescence as a measure of constitutive gene expression. PET using benzalkonium chloride and benzyl alcohol showed no significant difference between the bioluminescent method and the plate count method. Good correlations between bioluminescence, CFU count and fluorescence were obtained for benzalkonium chloride (BKC) concentrations (R>0.9) between 0.0003% and 0.0025% against strains lysR25, lppR4 and tatH5. Similarly, good correlations (R>0.9) between the three parameters were obtained for benzyl alcohol (BA) concentrations between 0.125% and 2% against strains lysR25, lppR4 and tatH5. The bioluminescent method and traditional plate counting method were equivalent for concentrations of BKC (0.0003 - 0.02%) and BA (0.25 - 2%) during preservative efficacy tests. These bioluminescent constructs therefore are good candidates for selection for preservative efficacy testing. The bioluminescent method and traditional plate counting method were also found to be equivalent for construct tatH5 at a concentration of 0.125% BA. PET testing with BKC and BA showed that tatH5-pMElux (R>0.9) had consistently high correlation coefficients between CFU and relative bioluminescence. Together with the results from growth and death kinetics, where tatH5 showed the greatest constitutive expression, it can be concluded that P. aeruginosa ATCC 9027 tatH5-pMElux is the best construct for testing various antimicrobial agents. This study has shown that according to the pharmacopoeial requirements, the bioluminescent method is more accurate, precise and equivalent to the traditional plate counting method and therefore can be utilised instead of the traditional plate counting method for the purpose of preservative efficacy testing.
25
Colquhoun, Adrian. "The development of a rapid method for the analysis of strontium-90 in environmental samples and its application to soils, lake and marine sediments from West Cumbria." Thesis, Lancaster University, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.358928.
Full text
26
Gill, Anjandeep Singh. "Kunskapsnivå vid informationssystemsutveckling : med hjälp av RAD-verktyg." Thesis, Högskolan i Skövde, Institutionen för kommunikation och information, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-6585.
Full textAbstract:
Det har genom åren förts en diskussion om RAD och andra snabba utvecklingsmetoder. Det här arbetet handlar det om att utveckla IS med hjälp av RAD-verktyg. Utveckling kommer att göras av olika personer med varierande IT-erfarenheter. Genom att låta personerna vara med i observationen finns det en möjlighet att se vilka som klarar av att utveckla ett IS liknande scenariot som används i studien. Ett scenario har utvecklats och verifierats med hjälp av en IT-forskare på Högskolan i Skövde, att det är ett rimligt scenario. Vidare har det i sin tur används som underlag till intervjuer för att verifiera ifall det är ett troligt och rimligt scenario som har en verklighetsanknytning. Ett antal deltagare med olika IT-erfarenheter har fått möjligheten att lösa problemet i scenariot med hjälp av ett RAD-verktyg. Deltagarna har blivit indelade i tre grupper utifrån deras IT-erfarenheter, de tre grupperna är: inga databaskunskaper, grundläggande databaskunskaper och avancerad databaskunskaper. Deltagarna har en begränsad tid på sig, under den tiden ska de försöka lösa problemet genom att bygga ett IS. I resultatet framgår det vilken typ av IT-kunskapsnivå som är rimlig att ha om användaren ska utveckla ett IS likt scenariot. Syfte med arbetet har varit att ta reda på vilken kategori av deltagare som kommer att klara av utvecklingen av ett informationssystem genom att använda sig av ett RAD-verktyg. Utifrån de observationen som genomfördes så var det bara användare på avancerad databaskunskaper som klarade av att lösa uppgiften. Övriga användare avbröt observationen på grund av olika anledningar.
27
Jindráček, Petr. "Frameworky pro rychlý vývoj webových aplikací Ruby on Rails a Spring Roo." Master's thesis, Vysoká škola ekonomická v Praze, 2014. http://www.nusl.cz/ntk/nusl-192446.
Full textAbstract:
The topic of this master's thesis is a comparison of web Rapid Application Development frameworks Ruby on Rails and Spring Roo. The paper focuses on creating extensive overview of pros and cons of the subjected tools from the web developer's point of view to enhance his awareness about the subject, also to come up with new questions for further analysis or even convince him to use one of the frameworks in the real projects. Firstly, the paper contains a theoretical overview of the common conceptions for better understanding of the following parts and then specific principles for each of the selected frameworks. Secondly, there is a practical part. On one hand it demonstrates the implementation of a reference application using both platforms to illustrate the practical distinctions. On the other hand, it also contains an overall comparison based on the defined methodology. Altogether, it should form a comprehensive comparison of the selected frameworks for web developers interested in Ruby and Java platforms.
28
Eriksson, Magnus, and Erik Jonsson. "Migration av distribuerad relationsdatabas för lagring i webbläsare." Thesis, Uppsala universitet, Informationssystem, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-202588.
Full textAbstract:
An increasing amount of companies and organizations are starting to implement the use of cloud computing in their business. This trend results in that software, which was previously sold and distributed to the customers whom then had to install the software on their own computers, now is being replaced with Software as a Service (SaaS). SaaS makes software available through the customers’ browsers, which results in that the service providers only have to administer a single application. The process to migrate a distributed application to a service delivered as a SaaS lacks sufficient investigation; this paper will provide some guidelines for conducting such a pro- cess. During the work on this paper, a prototype of a service delivered as a SaaS has been devel- oped with the intention to test, among other things, how a distributed relational database can be converted to a key/value pair storage. A conversion of this kind enables data to be stored locally in the customers’ browsers, which relieves some pressure on the server as well as enables the application to be used in offline-mode. The paper results in three guidelines which should be considered when planning to migrate software to a service delivered as a SaaS with a local data- base; Think before you act, Don’t expose your soul and Size matters. These guidelines describe how a migration process should be planned, when an application is not deemed appropriate to migrate and when a conversion of the database is not appropriate.Allt fler företag och organisationer börjar implementera användandet av olika molntjänster i sin verksamhet. Den här trenden medför att programvaror, som tidigare sålts och distribuerats till kunder vilka sedan själva får installera dem på sina egna datorer, nu börjar ersättas med en Soft- ware as a Service (SaaS). Det innebär att programvaran istället finns tillgänglig på Internet via kundernas webbläsare, något som medför att tjänsteleverantören enbart behöver administrera en enda programvara. Processen att migrera en distribuerad programvara till en SaaS-tjänst saknar ordentlig utredning, det här arbetet syftar därför till att ta fram några vägledande riktlinjer för en sådan process. Under arbetets gång har en prototyp av en SaaS-tjänst utvecklats med syfte att testa bland annat hur en tidigare distribuerad relationsdatabas kan konverteras till nyckel/värde- par. En sådan konvertering möjliggör lokal lagring av data i kundernas webbläsare, vilket mins- kar belastningen på servern samt erbjuder möjligheten att arbeta offline. Arbetet resulterar i tre riktlinjer att beakta då en migration till en SaaS-tjänst med lokal databas planeras; Tänk efter, före, Blotta inte din själ och Storleken har betydelse. Riktlinjerna beskriver hur en migrations- process bör planeras, när en applikation inte anses lämplig att migrera samt när en konvertering av databasen inte anses lämplig.
29
Marek, Lukáš. "Rámec pro rychlý vývoj GUI klientských aplikací post-relačních databází." Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2013. http://www.nusl.cz/ntk/nusl-236414.
Full textAbstract:
This thesis deals with design and implementation of a framework for rapid application development that use multimedia, spatial and temporal databases. Introduces readers with applied technologies and framework design. Framework design contains three graphical components that can be used in Java applications using Java Swing graphics library.
30
Luong, The Nhan. "Modélisation centrée utilisateur final appliquée à la conception d'applications intéractives en géographie : une démarche basée sur les contenus et les usages." Thesis, Pau, 2012. http://www.theses.fr/2012PAUU3034/document.
Full textAbstract:
Le point de départ de cette thèse a pour origine les difficultés constatées dans la communauté EIAH pour concevoir des applications éducatives exploitant des informations géographiques. A terme, il s'agit de proposer une nouvelle plateforme susceptible de rendre possible et opérationnel la conception d'applications Web géographiques portées par des utilisateurs non-informaticiens de façon autonome. La proposition scientifique est basée sur un processus de conception piloté par les contenus et par les interactions. Il est opérationnalisé dans une plateforme nommée WINDMash offrant aux concepteurs un environnement visuel de spécification et d'évaluation des interactions. Nous proposons un modèle unifié sous-jacent de description des applications Web géographiques comportant trois facettes qui permettent de représenter les contenus géographiques manipulés, de les afficher sur une interface graphique et de décrire le comportement de l’application (scénario d’interaction) à l'aide d'un langage visuel dont le formalisme graphique est inspiré du diagramme de séquence UML. En utilisant des techniques d'Ingénierie Dirigée par les Modèles, la plateforme WINDMash permet de générer automatiquement le code de l'application finale sur la base des instances de trois facettes du modèle unifié. La plateforme WINDMash utilise pour cela l’API WIND (Web INteraction Design) que nous avons programmée. Les concepteurs peuvent ainsi prototyper rapidement des applications Web géographiques correspondant à leurs besoinsThe starting point of this thesis is to deal with the difficulties encountered in the TEL community for designing educational applications exploiting geographic information. Ultimately, it is to provide a new framework allowing for the operational design of geographic Web applications for experts in the domain (and particularly for teachers). The scientific proposal is based on a design process driven by contents and interaction. It is operationalized on a framework called WINDMash offering designers a visual environment for simply specifying and immediately evaluating interactions. The unified model for describing geographic Web applications has three parts: one for representing geographic contents, one for displaying them on a graphical user interface (GUI) and one for describing the behaviour of the application using a visual language whose graphical formalism is based on the UML diagram sequence. Using Model-Driven Engineering (MDE) techniques, the WINDMash framework can automatically generate the code of the final application based on the instances of three parts of the unified model. The WINDMash framework used for this the WIND API (Web INteraction Design) that we programmed. Designers can thus rapidly prototype geographic Web applications corresponding to their needs
31
Larabi, Islam Amine. "Nouveaux produits de synthèse : analyse, consommation et métabolisme ; Applications cliniques et médicolégales Rapid and simultaneous screening of new psychoactive substances and conventional drugs of abuse. A comparative study of Biochip Array Technology versus LC-MS/MS in whole blood and urine Development of a sensitive untargeted liquid chromatography– high resolution mass spectrometry screening devoted to hair analysis through a shared MS2 spectra database: A step toward early detection of new psychoactive substances Validation of an UPLC-MS/MS method for the determination of sixteen synthetic cannabinoids in human hair. Application to document chronic use of JWH-122 following a non-fatal overdose Development and validation of liquid chromatography-tandem mass spectrometry targeted screening of 16 fentanyl analogs and U-47700 in hair: Application to 137 authentic samples Prevalence and Surveillance of Synthetic Cathinones Use by Hair Analysis: An Update Review Prevalence of New Psychoactive Substances(NPS) and conventional drugs of abuse (DOA) in high risk populations from Paris(France) and its suburbs A cross sectional study by hair testing(2012–2017) Evaluation of drug abuse by hair analysis and self-reported use among MSM under PrEP: Results from a sub-study of the ANRS-IPERGAY trial. Hair testing for 3‑fluorofentanyl, furanylfentanyl, methoxyacetylfentanyl, carfentanil, acetylfentanyl and fentanyl by LC–MS/MS after unintentional overdose Drug‐facilitated sexual assault (DFSA) involving 4‐methylethcathinone (4‐MEC),3,4‐Methylenedioxypyrovalerone (MDPV), and doxylamine highlighted by hair analysis Metabolic Profiling of Deschloro-N-ethyl-ketamine (O-PCE) and identification of new target metabolites in urine and hair using human liver microsomes and high-resolution accurate mass spectrometry." Thesis, université Paris-Saclay, 2020. http://www.theses.fr/2020UPASL029.
Full textAbstract:
L’objectif de ce travail a été de développer deux approches analytiques dédiées à l’analyse toxicologique des nouveaux produits de synthèse (NPS) dans différentes matrices biologiques (sang, urine et cheveux). La première est basée sur le criblage non ciblé par chimiluminescence sur biopuces et chromatographie liquide couplée à la spectrométrie de masse haute résolution (LC-HRMS) et la deuxième correspond à un criblage ciblé par spectrométrie de masse en tandem (LC-MS/MS). Ces deux approches ont ensuite été appliquées dans des études observationnelles pour évaluer la consommation de NPS dans des populations à risques de surdosage, de pharmacodépendance ou de soumission chimique dans un contexte clinique ou médico-judiciaire.La dernière partie a été consacrée au développement d’un nouvel outil analytique de traitement des données issues de la LC-HRMS qui a permis d’étudier le métabolisme de 9 NPS in vitro sur des cultures de microsomes du foie humain (HLM) et in vivo sur des échantillons biologiques d’usagers de ces drogues. Cette dernière approche a permis la création d’une bibliothèque de spectres de haute résolution composée de 228 métabolites dont certains ont été proposés comme marqueurs pertinents d’exposition aux NPS dont ils sont issus.Ce travail a été concrétisé par la rédaction de 10 publications scientifiques et a permis d’initier plusieurs collaborations pluridisciplinairesThe aim of the present work was to develop two analytical approaches dedicated to the analysis of new psychoactive substances in different biological matrices (blood, urine and hair). The first approach is based on untargeted screening by both biochip array technology chemiluminescence assay and liquid chromatography coupled to high resolution mass spectrometry (LC-HRMS) and the second corresponds to a targeted screening by liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS). These two approaches were then applied in observational studies to assess the consumption of NPS in high risk populations (overdose, drug abuse, drug facilitated crimes) in clinical and forensic settings. The last part of the work was devoted to the development of a new analytical tool for LC-HRMS data processing which made it possible to study the metabolism of 9 NPS In vitro on human liver microsomes (HLM) and In vivo in biological samples from drug users. This approach has enabled the creation of HRMS spectral library containing 228 metabolites, some of which have been proposed as relevant markers of NPS exposure.This work has resulted on 10 scientific publications and allowed to initiate many multidisciplinary collaborations
32
"RMADS: development of a concurrent Rapid Manufacturing Advice System." Universitat Politècnica de Catalunya, 2009. http://www.tesisenxarxa.net/TDX-0122110-185710/.
Full text
33
(6634457), Suyash Agrawal. "Using Rapid Application Development for Software Development Projects." Thesis, 2019.
Find full textAbstract:
In the modern era where technology is constantly evolving, it is important to evaluate new technological tools and approaches in order to gauge their potential for adoption. Rapid Application Development (RAD) has highly evolved over the years, but it has not seen much response at the university level. Several studies show that perceptions of usability form the basis of acceptance or rejection of new tools and applications. Thus, running a usability study on a specific RAD tool coupled with autoethnographic documentation of specific development experience with that tool has the potential to encourage university faculty/staff to consider teaching/using it.
This research study seeks to understand developers' perceptions regarding the usability aspect of Mendix, a Rapid Application Development (RAD) tool. Both qualitative and quantitative approaches were employed to discover and understand the extent of perceived usefulness, ease of use and satisfaction with the tool. The results of the study presented a case for academicians on the viability of teaching RAD or using Mendix for their web application development needs. The study ultimately sought to help university faculty understand what to expect while teaching RAD to students from computing background and also help them decide if they would like to use tools like Mendix for their software development projects or continue to use specific coding languages (traditional software development) for software development projects.
34
Lin, Chih-Yang, and 林致揚. "Development and Application of Rapid Tooling Technology." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/53310092748662892191.
Full textAbstract:
碩士明志科技大學
機電工程研究所
99
The major research field of this research is making the mold of aspherical lens with the rapid tooling (RT) technology and the research and development of the green RT making technology and the technology of silica in complex and large geometrical form. This paper first makes the mold of aspherical lens with silica and assesses its feasibility. Then the research introduces the green manufacturing (GM) technology into RP technology to reduce the manufacturing cost without affecting the surface accuracy of the mold. Finally, GM technology is applied to the development of the silica in complex and large geometrical form to maximize its effectiveness. Furthermore, the paper also proposes the technology used for manufacturing the silica in complex and large geometrical form to be used as know-how in the future. Finally, this research integrates GM technology and RT technology to manufacture the mold of aspherical lens. Thereinto, because the silica is soft, it is used to manufacture the intermediary mold, which will be used to research and manufacture the finally required mold of aspherical lens of aluminum-epoxy. Inject the molding aspherical lens copy with the mold and get the error value through non-contact measurement, and feed it back to the radius of curvature of the prototype. At last, the feedback data will be used to manufacture the second mold of aspherical lens of aluminum-epoxy; observe its compensation. It can be known from the research result that for applying the RT technology to manufacture the mold of aspherical lens, the surface roughness and the surface curvature are both within the allowed values and developing the mold with GM technology and RT technology can really reduce the costs effectively. Therefore, manufacturing the mold with GM technology and RT technology is feasible.
35
Cheng, Man-Shin, and 鄭錳新. "Project characteristics, concurrent activity, and project performance in application software development." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/10140027545302185082.
Full textAbstract:
博士國立政治大學
企業管理學系
89
Concurrent engineering is popular in developing hardware product. This paper focus on software development with concurrent engineering, and study the relationship in project characteristics and project performance. The paper offers several implications for practicing managers in software development. First, it demonstrates that concurrency is according with software categories. Secondly, project managers should consider project complexity, requirement stableness, dependency of task, and communication method in software development. Further, stage of coding program can be high concurrency with stage of unit testing.
36
Shiu, Shiou-Ru, and 許修繻. "Technological Development and Application of Hybrid Rapid Tooling Technology." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/24971011878768915246.
Full textAbstract:
碩士明志科技大學
機電工程研究所
101
The key to survival in the modern manufacturing industry is to shorten product development period and reduce cost in order to quickly push diversified products to the market and seize opportunities. As a result, the rapid tooling (RT) technology has been developed. In this study the RT technology has been utilized to make the mold of Fresnel lens, where the silicone is used as the intermediate mold, and the epoxy resin is used to make hot embossing mold. However, the traditional RT mold is made of epoxy resin with a rather high cost. Therefore, for cost saving and enhancement of geometry accuracy, in this study the hybrid mold technology has been proposed based on the integration of RT mold and backing material. The results of this study have indicated a transcription rate of 97.12% of hot embossing mold of Fresnel lens made by RT technology, while the surface roughness of the hot embossing finished product is 8.95% higher than the prototype. The hybrid mold technology developed based on the integration with backing material has led to 78.77% of cost reduction and a 77.77% improvement on geometry accuracy. The residual stress of hot embossing is lower than injection molding, and the surface energy is only 29.1 mN/m, which is very suitable for stripping. Therefore, the hybrid mold technology proposed in this study has led to the advantages of simple fabrication method, low fabrication cost, low residual stress, high geometry accuracy and superior dimension accuracy.
37
Ferreira, Luís Filipe Rocha Maia. "FV-RAD : a practical framework for rapid application development." Dissertação, 2009. http://hdl.handle.net/10216/66702.
Full text
38
Ferreira, Luís Filipe Rocha Maia. "FV-RAD : a practical framework for rapid application development." Master's thesis, 2009. http://hdl.handle.net/10216/66702.
Full text
39
Shian-Ru, Ke. "Design and Implementation of RApid Multimedia Application Development (RAMAD) System." 2005. http://www.cetd.com.tw/ec/thesisdetail.aspx?etdun=U0001-2807200514502600.
Full text
40
Chiang, Chun-pin, and 江淳彬. "Development and application of rapid refrigeration technology for ice coffee." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/68983903150951960949.
Full textAbstract:
碩士聖約翰科技大學
電機產業研發碩士專班
100
The development of refrigeration engineering not only stores up food but also develops and manufacture specific features on demand. Thus, this thesis proposes a kind of development and application of rapid refrigeration technology for ice coffee.The temperature controller is designed based on upper and lower limits of the temperature for ice coffee and used to perform experiments by using different amounts of refrigerant (142g, 127g, 112g, 97g) in the specific refrigeration machine. Our research focuses on the evaluation of the design to the temperature range and switch control with fixed amount of refrigerant, and investigates the influence of different amount of refrigeration to the refrigerant system. We propose our methodology and collect the best results of 6℃ and 9℃ controllers, respectively with different amount of refrigerant. We then perform cross-comparison with these two results. Our research keeps the arrival time to reach the refrigeration temperature, maintenance cost, the above-freezing evaporation barrel, and equipment life in mind. We conclude that the design of 6℃ controller and 112g of refrigerant has the best performance for rapid refrigeration technology for ice coffee.
41
Ke, Shian-Ru, and 柯憲儒. "Design and Implementation of RApid Multimedia Application Development (RAMAD) System." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/87634783396743462656.
Full textAbstract:
碩士國立臺灣大學
資訊工程學研究所
93
Nowadays, due to the increasing amount of multimedia content and the growing demand for rich-media presentations, this creates a need to build tools that enable everyday people to develop multimedia applications by themselves. Moreover, people would like to create personalized applications to realize their distinctive ideas. Although many emerging standards (such as MPEG-4) and media formats (such as QuickTime, Flash, etc.) are made to meet this demand, there is not a flexible and programmable framework to bridge the gap in the development process between traditional applications and multimedia applications. Even for an experienced developer, developing a multimedia application remains difficult. Thus, we consider the research challenge to find a methodology for rapid and ease-of-use development of multimedia applications. In this thesis, we propose a design and implementation of a RApid Multimedia Application Development (RAMAD) system. The design considerations are as follows: 1.In order to deal with complex multimedia content, we adopt MPEG-4 as a core component for presentation. 2.In order to reuse conventional Graphic User Interface (GUI) in RAMAD system, we include existing GUI components and make them interactive with the MPEG-4 component. 3.In order to facilitate the development process, we use a scripting language, i.e. Python, to glue all Python extension components. Python has some good features for debugging and testing during developing stage, such as interpreting and dynamic binding. 4.In order to deploy RAMMAD system on different platforms, we develop most components in a cross-platform manner, such as GUI and MPEG-4. This makes RAMAD application portable while migrating to other platform. With RAMAD system, users can rapidly build a proof-of-concept prototype of a target multimedia application, and show the significant idea to other people. Furthermore, they can refine the proof-of-concept prototype to be a full-blown multimedia application, which is portable to different platforms.
42
Tsai, Ren-Lung, and 蔡仁隆. "Development and Application for Low-Pressure Wax Injection Rapid Toolings." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/r6cfjc.
Full text
43
HSU, WEI-TSONG, and 徐瑋聰. "Development and Application of Rapid Tooling with Conformal Cooling Channels." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/hjn77w.
Full textAbstract:
碩士明志科技大學
機械工程系機械與機電工程碩士班
106
Since metallic-resin rapid tooling has poor thermal conductivity, the product made with such mold tends to have longer molding cycle comparing with that made with conventional steel mold. To overcome this challenge, a novel wax-injection mold with cooling channels of complicated geometry was designed in this study by integrating 3D printing and rapid tooling technologies. During the fabrication of rapid tooling, cooling channel supporting model was included. In the end, acetone was used to remove the cooling channel supporting model, forming a wax-injection mold with conformal cooling channels. After evaluating the feasibility of experiments which will be carried out in this study, molds with different cooling designs will be fabricated to verify their practical applications. In this study, four low-pressure, wax-injection silicon molds, namely no-cooling mold, traditional cooling mold, parallel-connected conformal cooling mold and serial-connected conformal cooling mold, will be fabricated and wax-injection temperature experiments will be carried out for these four types of molds.From the experimental results, it is found that the time to reach mold-opening temperature is 150 minutes for no-cooling mold, 54 minutes for traditional cooling mold, 21 minutes for parallel-connected conformal cooling mold and 14 minutes for serial-connected conformal cooling mold.If no-cooling mold is used as the base to compare the cooling efficiency of various molds with different cooling designs, the operation time saved is 63% for traditional cooling mold, 86% for parallel-connected conformal cooling mold and 91% for serial-connected conformal cooling mold. The above result suggests that conformal cooling design produces better cooling efficiency than traditional cooling design, while serial-connected conformal cooling mold gives better cooling efficiency than parallel-connected conformal cooling mold.
44
Fonseca, Luís Miguel Guimarães Pimentel. "Exploring Rapid Application Development for Android with Scala and SBT." Dissertação, 2014. https://repositorio-aberto.up.pt/handle/10216/75085.
Full textAbstract:
Android development, despite being widely practiced nowadays, it is still troublesome as developers need to learn very complex APIs to start implementing their projects. Furthermore, the Java programming languages presents design issues that have been addressed in modern languages, which also unnecessarily increases the complexity in Android development.Following the lessons learned from web development, Model-View-Controller (MVC) frameworks can simplify development, providing an abstraction layer in order to create complex applications. Extensibility via plugins can also provide a set of usage patterns, such as showing lists, managing local databases, push notifications and so on.This thesis aims at simplifying the development process through the adoption of the best design patterns, along with the introduction of the Scala programming language instead of Java. We will be will taking advantage of the Scala Build Tool (SBT) to work as plugin and as a build manager.
45
Dunseith, Roy H. "A taxonomy of risks in rapid application development (RAD) projects." Thesis, 2014. http://hdl.handle.net/10210/10294.
Full text
46
Lu, Ying-Chih, and 呂英志. "Development Strategies and Technology Application of Bus Rapid Transit System." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/73826564639458291709.
Full textAbstract:
博士國立臺灣大學
土木工程學研究所
97
Bus Rapid Transit (BRT) system integrates efficiency of rail transport and flexibility of bus transport to achieve fast, convenient, comfortable, and low pollution goals. Due to features of comparatively low cost and short construction period, a well planned and designed BRT network can also help of implementing the Transit-Oriented Development (TOD) policy, which has been recognized as an essential policy in land use planning and urban development for achieving sustainability. This study explores how various strategies and technology application for BRT to attain TOD. First, various BRT systems in representative cities are then compiled and compared based on literature review and field survey. Strategies and technologies of applying BRT for TOD planning are then proposed and evaluated. Results of this research should help of defining the role and function of BRT systems and of selecting appropriate technologies for development of BRT projects.
47
Chen, Ming-Jey, and 陳明傑. "Application of a DLP Technique for Rapid Prototyping System Development." Thesis, 2002. http://ndltd.ncl.edu.tw/handle/38341935257679383281.
Full textAbstract:
碩士國立臺灣科技大學
工程技術研究所自動化及控制學程
90
This paper presents a new Rapid prototyping system by using a DLP (Digital Light Processor) as light source. The PC-based controller generates the layer patterns by giving the CAD model (STL file) of the work piece to be made. This DLP light source can directly solidify the photosensitive resin layer by layer without LCD mask. In this research, the output property of a DLP light source is analyzed. Firstly, a photosensitive diode mounted in a 3-Axis machine is used to measure the intensity distribution of a DLP output. The characteristic of a photosensitive resin is also investigated by exposing it with DLP light. It is showed that the intensity distribution of a DLP is better than a traditional projector. The better gray degree performance and high contrast of the DLP can shorten the curing time of a photosensitive resin. From the experimental results, the curing efficiency of the DLP-based RP machine is much better than LCD-based RP machine due to its direct illumination. It can save the curing time even more than 50% without losing the contour of a work piece. The curing resolution can reach up to 0.1mm per pixel. It takes almost 3 hours for building a aligned teeth model. It will improve the application of a mask-based RP system.
48
Ile, Dan Mihai. "Desenvolvimento de um RAD para aplicações WEB (Rapid Application Development)." Master's thesis, 2009. http://hdl.handle.net/10451/5025.
Full textAbstract:
Trabalho de projecto de mestrado em Engenharia Informática, apresentado à Universidade de Lisboa, através da Faculdade de Ciências, 2009Este documento descreve detalhadamente todo o trabalho de estágio desenvolvido durante 9 meses na empresa GEDI (Gabinete de Estudos e Divulgação Informática, SA) pelo aluno Dan Mihai Ile, no âmbito do Mestrado em Engenharia Informática da Faculdade de Ciências da Universidade de Lisboa. Consta num projecto desenvolvido com objectivo de melhorar a qualidade, metodologia de desenvolvimento e utilização da framework SIAG tanto pelos utilizadores como pela equipa de desenvolvimento da mesma empresa. Pretende-se desenvolver um sistema que permita a criação de componentes de interface dinâmicos directamente no browser utilizando tecnologias como AJAX com interface web 2.0, GWT, web-services e sistema de mensagens para comunicação distribuída entre vários componentes da framework.
This document describes in detail every aspect of the project undertaken during 9 months at the GEDI company by the student Dan Mihai Ile, in the Computer Engineering Project at Faculdade de Ciências da Universidade de Lisboa. The final project should improve quality, developing methodology and utilization of the SIAG framework by the users and also by the developing team of the company. The aim of the project is to develop a system that should allow the dynamic creation of interface components directly in the browser using technologies such as AJAX with web 2.0 interface, GWT (Google Web Toolkit), web-services and messaging system for the distributed communication between several components of the framework.
Esta versão do documento está incompleta devido à natureza confidencial de algumas das suas partes.
49
Fonseca, Luís Miguel Guimarães Pimentel. "Exploring Rapid Application Development for Android with Scala and SBT." Master's thesis, 2014. https://repositorio-aberto.up.pt/handle/10216/75085.
Full textAbstract:
Android development, despite being widely practiced nowadays, it is still troublesome as developers need to learn very complex APIs to start implementing their projects. Furthermore, the Java programming languages presents design issues that have been addressed in modern languages, which also unnecessarily increases the complexity in Android development.Following the lessons learned from web development, Model-View-Controller (MVC) frameworks can simplify development, providing an abstraction layer in order to create complex applications. Extensibility via plugins can also provide a set of usage patterns, such as showing lists, managing local databases, push notifications and so on.This thesis aims at simplifying the development process through the adoption of the best design patterns, along with the introduction of the Scala programming language instead of Java. We will be will taking advantage of the Scala Build Tool (SBT) to work as plugin and as a build manager.
50
蕭慧慈. "A study on the application of concurrent engineering to product design and development." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/01172590020181542907.
Full text