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Journal articles on the topic 'Rapid mixing device'

Author: Grafiati

Published: 4 June 2021

Last updated: 17 February 2022

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1

Kahn, James, Robert N. Dutnall, Kimberly Matulef, and Leigh A. Plesniak. "Measurement of kon without a rapid-mixing device." Biochemistry and Molecular Biology Education 38, no. 4 (2010): 238–41. http://dx.doi.org/10.1002/bmb.20369.

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2

Yasui, Takao, Yusuke Omoto, Keiko Osato, et al. "Microfluidic baker's transformation device for three-dimensional rapid mixing." Lab on a Chip 11, no. 19 (2011): 3356. http://dx.doi.org/10.1039/c1lc20342h.

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3

Beck, Christian, Sameer V. Dalvi, and Rajesh N. Dave. "Controlled liquid antisolvent precipitation using a rapid mixing device." Chemical Engineering Science 65, no. 21 (2010): 5669–75. http://dx.doi.org/10.1016/j.ces.2010.04.001.

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4

TAKAHASHI, Satoshi. "Protein, Solution Mixing and Microfabrication- Observation of Protein Folding Dynamics by Rapid Mixing Device -." Review of Laser Engineering 37, no. 7 (2009): 515–20. http://dx.doi.org/10.2184/lsj.37.515.

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5

Dingfelder, Fabian, Bengt Wunderlich, Stephan Benke, et al. "Rapid Microfluidic Double-Jump Mixing Device for Single-Molecule Spectroscopy." Journal of the American Chemical Society 139, no. 17 (2017): 6062–65. http://dx.doi.org/10.1021/jacs.7b02357.

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6

Hsu, Hsiang Chen, Hsi Chien Liu, and Cheng Jiun Han. "Fabrication of Microfluidic Rapid Micromixer." Key Engineering Materials 467-469 (February 2011): 2013–17. http://dx.doi.org/10.4028/www.scientific.net/kem.467-469.2013.

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A microfluidic multi-cylindric rapid micromixer is fabricated in the present paper. The key features in the presented MEMS-based microchannel design are (1) micro pump (2) Y-junction type channel (3) cylindric obstacle (4) notch with the edge of sharp teeth. Two different fluids (DI water and red ink) were pumped and injected into Y-type channel, and the fluids were broken-up by a cylindric obstacle in the center of tapered microchannel. The chaotic convection occurs in the mixing channel behind the cylindric obstacle. The mixing index is defined to qualify the mixing efficiency, which demonst

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7

Shanko, Eriola-Sophia, Yoeri van de Burgt, Patrick D. Anderson, and Jaap M. J. den Toonder. "Microfluidic Magnetic Mixing at Low Reynolds Numbers and in Stagnant Fluids." Micromachines 10, no. 11 (2019): 731. http://dx.doi.org/10.3390/mi10110731.

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Microfluidic mixing becomes a necessity when thorough sample homogenization is required in small volumes of fluid, such as in lab-on-a-chip devices. For example, efficient mixing is extraordinarily challenging in capillary-filling microfluidic devices and in microchambers with stagnant fluids. To address this issue, specifically designed geometrical features can enhance the effect of diffusion and provide efficient mixing by inducing chaotic fluid flow. This scheme is known as “passive” mixing. In addition, when rapid and global mixing is essential, “active” mixing can be applied by exploiting

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8

Besnea, Daniel, Alina Spanu, Iuliana Marlena Prodea, Gheorghita Tomescu, and Iolanda Constanta Panait. "Constructive Optimisation of the Propeller Type Mixing Devices Using the Virtual and Rapid Prototyping." Revista de Chimie 68, no. 3 (2017): 453–58. http://dx.doi.org/10.37358/rc.17.3.5477.

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The paper points out the advantages of rapid prototyping for improving the performances/constructive optimization of mixing devices used in process industries, here exemplified to propeller types ones. The multidisciplinary optimization of the propeller profile affords its design using parametric CAD methods. Starting from the mathematical curve equations proposed for the blade profile, it was determined its three-dimensional virtual model. The challenge has been focused on the variation of propeller pitch and external diameter. Three dimensional ranges were manufactured using the additive man

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9

Zhang, Ke, Ruifeng Liu, Tom Irving, and David S. Auld. "A versatile rapid-mixing and flow device for X-ray absorption spectroscopy." Journal of Synchrotron Radiation 11, no. 2 (2004): 204–8. http://dx.doi.org/10.1107/s0909049503028474.

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10

Zinck, Nicholas, Ann-Kathrin Stark, Derek J. Wilson, and Michal Sharon. "An Improved Rapid Mixing Device for Time-Resolved Electrospray Mass Spectrometry Measurements." ChemistryOpen 3, no. 3 (2014): 109–14. http://dx.doi.org/10.1002/open.201402002.

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11

Zhou, Ran, Athira N. Surendran, Marcel Mejulu, and Yang Lin. "Rapid Microfluidic Mixer Based on Ferrofluid and Integrated Microscale NdFeB-PDMS Magnet." Micromachines 11, no. 1 (2019): 29. http://dx.doi.org/10.3390/mi11010029.

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Ferrofluid-based micromixers have been widely used for a myriad of microfluidic industrial applications in biochemical engineering, food processing, and detection/analytical processes. However, complete mixing in micromixers is extremely time-consuming and requires very long microchannels due to laminar flow. In this paper, we developed an effective and low-cost microfluidic device integrated with microscale magnets manufactured with neodymium (NdFeB) powders and polydimethylsiloxane (PDMS) to achieve rapid micromixing between ferrofluid and buffer flow. Experiments were conducted systematical

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12

Dhibar, Subhendu, Arka Dey, Amiya Dey, et al. "The development of a rapid self-healing semiconducting monoethanolamine-based Mg(OH)2 metallogel for a Schottky diode application with a high ON/OFF ratio." New Journal of Chemistry 43, no. 39 (2019): 15691–99. http://dx.doi.org/10.1039/c9nj03457a.

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13

Kontziampasis, Dimitrios, David P. Klebl, Matthew G. Iadanza, et al. "A cryo-EM grid preparation device for time-resolved structural studies." IUCrJ 6, no. 6 (2019): 1024–31. http://dx.doi.org/10.1107/s2052252519011345.

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Structural biology generally provides static snapshots of protein conformations that can provide information on the functional mechanisms of biological systems. Time-resolved structural biology provides a means to visualize, at near-atomic resolution, the dynamic conformational changes that macromolecules undergo as they function. X-ray free-electron-laser technology has provided a powerful tool to study enzyme mechanisms at atomic resolution, typically in the femtosecond to picosecond timeframe. Complementary to this, recent advances in the resolution obtainable by electron microscopy and the

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14

Xi, Xinge, Ronghui Wang, Ping Yao, Lan Yao, Steve Tung, and Yanbin Li. "A Portable Biosensing Device with Magnetic Separation and Quantum Dot Bead Labeling for Simple, Rapid, and Quantitative Detection of Salmonella Typhimurium." Transactions of the ASABE 63, no. 6 (2020): 1947–55. http://dx.doi.org/10.13031/trans.13880.

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HighlightsA portable biosensing device was designed, fabricated, and evaluated for Salmonella detection.A mixing, separation, and detection chamber (MSDC) was developed and used for Salmonella detection.The disposable MSDC prevented cross-contamination and reduced costs.The device was mostly automated for Salmonella detection and feasible for in-field applications.Abstract. Foodborne pathogenic bacteria have caused numerous illnesses and economic losses in the U.S. and the world. It is highly important for food industries to conduct in-field screening for pathogenic bacteria to ensure food saf

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15

Gomez, Houari Cobas, Bianca Oliveira Agio, Jéssica Gonçalves da Silva, et al. "LTCC 3D MICROMIXERS FOR NON-MISCIBLE FLUIDS MICROEMULSION GENERATION." Additional Conferences (Device Packaging, HiTEC, HiTEN, and CICMT) 2016, CICMT (2016): 000096–102. http://dx.doi.org/10.4071/2016cicmt-wa15.

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Abstract The present work shows a ceramics microfluidic device for non-miscible fluids microemulsion generation using 3D serpentine micromixers. The technology used for device fabrication was Low Temperature Cofired Ceramics (LTCC) which allows us for complex, high temperature and pressure resistant 3D microfluidic devices. The proposed device aims to obtain microemulsion with controlled drop size, low dispersion index and high production volumes using Top-Down approach. Previous simulation work had showed 3D serpentine as one of the best structures for rapid mixing due the chaotic advection g

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16

Wang, Yao Nan, Ching Liang Liou, Ming Chang Wu, Chien Hsiung Tsai, and Lung Ming Fu. "Rapid Detection of Methanol in an Integration Microfluidic Chip." Key Engineering Materials 483 (June 2011): 364–69. http://dx.doi.org/10.4028/www.scientific.net/kem.483.364.

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A rapid and simple technique was developed for detecting methanol with very small amount of sample by using PMMA (Polymethyl-Methacrylate) microfluidic chip, which fabricated by a commercially available CO2 laser scriber. The experimental results indicate that linearity expression R2 can approximate 0.936 using the proposed integrating microfluidic chip when the 2 unit methanol oxidase (MOX) and basic fuchsin to detect methanol. Hence, the current device provides a valuable tool for rapid methanol detection, while its micro mixer system delivers a simple yet effective solution for mixing probl

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17

Sun, Yuan Yuan, Shi Bo Liu, Jia Yue Ren, Yong Bing Zhong, and Qiu Rui Jia. "Research on the Performance of P-i- n Type GaN Ultraviolet Photoelectric Detector." Advanced Materials Research 694-697 (May 2013): 1021–24. http://dx.doi.org/10.4028/www.scientific.net/amr.694-697.1021.

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GaN ultraviolet photoelectric detecting technique has important application value in the spacecraft, fire monitoring, ultraviolet communication and other fields. In this paper, p-type GaN samples were obtained after rapid annealing of GaN mixing Mg at 700~800°C. Then, p-i-n type GaN ultraviolet photoelectric detectors were fabricated on Al2O3 substrates by metal organic chemical vapor phase epitaxial deposition method. The devices have better rectifying behavior which can be demonstrated by the I-V curve. The response time of the device is 1.6µs and its higher responsivity is 0.95A/W.

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18

Kimura, T., S. Akiyama, S. Takahashi, Y. Harada, K. Ishimori, and I. Morishima. "The study on the burst phase of ribonuclease A folding using a rapid mixing device." Seibutsu Butsuri 40, supplement (2000): S161. http://dx.doi.org/10.2142/biophys.40.s161_1.

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19

Pinheiro, Teresa J. T., Jamie D. Venning, and J. Baz Jackson. "Fast Hydride Transfer in Proton-translocating Transhydrogenase Revealed in a Rapid Mixing Continuous Flow Device." Journal of Biological Chemistry 276, no. 48 (2001): 44757–61. http://dx.doi.org/10.1074/jbc.m109227200.

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20

Xu, Rui, Shijiao Zhao, Lei Nie, et al. "Study on the Technology of Monodisperse Droplets by a High-Throughput and Instant-Mixing Droplet Microfluidic System." Materials 14, no. 5 (2021): 1263. http://dx.doi.org/10.3390/ma14051263.

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In this study, we report a novel high-throughput and instant-mixing droplet microfluidic system that can prepare uniformly mixed monodisperse droplets at a flow rate of mL/min designed for rapid mixing between multiple solutions and the preparation of micro-/nanoparticles. The system is composed of a magneton micromixer and a T-junction microfluidic device. The magneton micromixer rapidly mixes multiple solutions uniformly through the rotation of the magneton, and the mixed solution is sheared into monodisperse droplets by the silicone oil in the T-junction microfluidic device. The optimal con

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21

Thiramanas, Raweewan, Rujira Wanotayan, Sakon Rahong, Kulachart Jangpatarapongsa, Pramuan Tangboriboonrat, and Duangporn Polpanich. "Improving Malaria Diagnosis via Latex Immunoagglutination Assay in Microfluidic Device." Advanced Materials Research 93-94 (January 2010): 292–95. http://dx.doi.org/10.4028/www.scientific.net/amr.93-94.292.

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Attempt to improve latex immunoagglutination assay, a rapid method in medical diagnostics, reporting as quantitative results was interested in this study by using microfluidic device. Sensitized latex was produced by physical adsorption of human polyclonal IgG antibody to Plasmodium falciparum malaria parasite onto carboxylated polystyrene particle. Conventional latex agglutination assay was firstly performed to verify specific interaction of antibody on the bead surface versus antigen in malaria plasma. The agglutinate size around 30 µm was observed under optical microscope. The proportion of

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22

Gretta, W. J., and C. R. Smith. "The Flow Structure and Statistics of a Passive Mixing Tab." Journal of Fluids Engineering 115, no. 2 (1993): 255–63. http://dx.doi.org/10.1115/1.2910133.

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Water channel flow visualization and anemometry studies were conducted to examine the flow structure and velocity statistics in the wake of a passive mixing tab designed for enhancement of cross-stream mixing by generation of flow structures characteristic of turbulent boundary layers. Flow visualization reveals that the mixing tab generates a wake comprising a combination of counter rotating, streamwise vortices enveloped by distinct hairpin vortex structures. The counter rotating streamwise vortices are observed to stimulate a strong ejection of fluid along the symmetry plane, which results

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23

Oktaviani, Oktaviani, and Yasuhisa Adachi. "Determination of the Rate of Salt-Induced Rapid Coagulation of Polystyrene Latex Particles in Turbulent Flow Using Small Stirred Vessel." Colloids and Interfaces 3, no. 1 (2018): 5. http://dx.doi.org/10.3390/colloids3010005.

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In our study, we revisited a previously reported method for evaluating the mixing intensity of uniform colloidal spheres in terms of their collision frequency, with the aim of evaluating the validity of this method in the case of a small stirred vessel equipped with an impeller with four paddles. The rates of the salt-induced rapid coagulation of polystyrene latex (PSL) particles with five different diameters were measured as functions of the rotation rate. The ad-hoc assumption of the linear additivity of the perikinetics and the orthokinetics of the coagulation process was used for the analy

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24

Adam, Tijjani, U. Hashim, and T. S. Dhahi. "Fabrication of PDMS Microfluidic via Room Temperature Rapid Prototyping Process." Advanced Materials Research 1109 (June 2015): 340–44. http://dx.doi.org/10.4028/www.scientific.net/amr.1109.340.

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An in-expensive way of fabricating PDMS microfluidic using room temperature curing process is presented which can be used for both laboratory and commercial scale. The microfluidic was designed using AutoCAD for master mold preparation and subsequently created with SU8 for rapid prototyping process; the micro mixer and the whole mixer were fabricated in less than without using costly fabrication steps. The device profiles were observed for structural integrity and evaluation by dropping two food coloring dyes through the two inlets and collecting the sample at outlet. Flow rate and mixing effi

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25

Chesler, N. C., and R. D. Kamm. "Performance Analysis of a Cardiac Assist Device in Counterpulsation." Journal of Biomechanical Engineering 120, no. 4 (1998): 437–45. http://dx.doi.org/10.1115/1.2798012.

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Performance of a cardiac assist device pumping chamber in counterpulsation was evaluated using numerical simulations of the unsteady, three-dimensional flow inside the chamber and an analytical model of the force required to eject and fill the chamber. The wall shear stress within the device was similarly computed and modeled. The analytical model was scaled to match the numerical results and then used to predict performance at physiological operating conditions. According to these models for a stroke volume of 70 ml, between 0.4 and 1.0 W is required for counterpulsation at a frequency of 1.3

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26

Natsuhara, Daigo, Keisuke Takishita, Kisuke Tanaka, et al. "A Microfluidic Diagnostic Device Capable of Autonomous Sample Mixing and Dispensing for the Simultaneous Genetic Detection of Multiple Plant Viruses." Micromachines 11, no. 6 (2020): 540. http://dx.doi.org/10.3390/mi11060540.

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As an efficient approach to risk management in agriculture, the elimination of losses due to plant diseases and insect pests is one of the most important and urgent technological challenges for improving the crop yield. Therefore, we have developed a polydimethylsiloxane (PDMS)-based microfluidic device for the multiplex genetic diagnosis of plant diseases and pests. It offers unique features, such as rapid detection, portability, simplicity, and the low-cost genetic diagnosis of a wide variety of plant viruses. In this study, to realize such a diagnostic device, we developed a method for the

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27

Chang, Ming, Jacque Lynn Gabayno, Ming Yi Chang, Yu Hao Lin, and Ke Wei Huang. "Magnetic Field-Driven Manipulation System and its Applications in Micromixing and Microablation." Applied Mechanics and Materials 736 (March 2015): 152–57. http://dx.doi.org/10.4028/www.scientific.net/amm.736.152.

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This study showcases two independent magnetic manipulation systems to remotely control the movement of Fe3O4 nanomaterial in microfluidic chips. One system utilizes a homogeneous rotating magnetic field to carry out magnetic stirring in 100 μm and 300 μm flow channels. The mixing results of this system revealed that adding Fe3O4 nanoparticles to the solution enhances the efficiency of the micromixer by twice as much that of a device without the nanomaterial. The second manipulation system utilizes oscillating magnetic field for rapid microablation of thrombus in a microchannel. A customizable

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28

Monteiro, Diana C. F., David von Stetten, Claudia Stohrer, et al. "3D-MiXD: 3D-printed X-ray-compatible microfluidic devices for rapid, low-consumption serial synchrotron crystallography data collection in flow." IUCrJ 7, no. 2 (2020): 207–19. http://dx.doi.org/10.1107/s2052252519016865.

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Serial crystallography has enabled the study of complex biological questions through the determination of biomolecular structures at room temperature using low X-ray doses. Furthermore, it has enabled the study of protein dynamics by the capture of atomically resolved and time-resolved molecular movies. However, the study of many biologically relevant targets is still severely hindered by high sample consumption and lengthy data-collection times. By combining serial synchrotron crystallography (SSX) with 3D printing, a new experimental platform has been created that tackles these challenges. A

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29

Xie, Jiaqing, Haoran Pang, Ruqian Sun, Tao Wang, Xiaoyu Meng, and Zhikang Zhou. "Development of Rapid and High-Precision Colorimetric Device for Organophosphorus Pesticide Detection Based on Microfluidic Mixer Chip." Micromachines 12, no. 3 (2021): 290. http://dx.doi.org/10.3390/mi12030290.

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The excessive pesticide residues in cereals, fruit and vegetables is a big threat to human health, and it is necessary to develop a portable, low-cost and high-precision pesticide residue detection scheme to replace the large-scale laboratory testing equipment for rapid detection of pesticide residues. In this study, a colorimetric device for rapid detection of organophosphorus pesticide residues with high precision based on a microfluidic mixer chip was proposed. The microchannel structure with high mixing efficiency was determined by fluid dynamics simulation, while the corresponding microfl

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30

Saien, Javad, Vahid Moradi, and Ali-Reza Soleymani. "Investigation of a jet mixing photo-reactor device for rapid dye discoloration and aromatic degradation via UV/H2O2 process." Chemical Engineering Journal 183 (February 2012): 135–40. http://dx.doi.org/10.1016/j.cej.2011.12.043.

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31

Panich, Sirirat, and Lerpong Pisnui. "All-in-One Flow Injection Spectrophotometric System for Field Testing." Applied Mechanics and Materials 879 (March 2018): 206–11. http://dx.doi.org/10.4028/www.scientific.net/amm.879.206.

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To date one of the most significant innovative trends in chemical analysis is to develop analytical instruments that have processed to analyze on-site. Such an apparatus should minimize problems related to sample transports, sample handlings and sample storages. Currently, a traditional wet analysis in laboratories has been replaced with a portable device designed to minimize problems from sending samples to the lab. One of the practical chemical methods which can be developed as the mobile device is flow injection analysis (FIA) because the scaled-down FIA manifolds have been already presente

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32

White, A. J., K. Drabble, and C. W. Wharton. "A stopped-flow apparatus for infrared spectroscopy of aqueous solutions." Biochemical Journal 306, no. 3 (1995): 843–49. http://dx.doi.org/10.1042/bj3060843.

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IR spectroscopy has been widely applied in the study of photo-activated biological processes such as photosynthesis, but has not been applied to the study of reacting systems which require rapid mixing of aqueous solutions. This has been due in part to the high pressure needed to make an aqueous solution flow rapidly through the 50 microns optical pathlength between the plates in an IR cuvette suitable for use with 2H2O and the high viscosity of the concentrated protein solutions required to generate measurable IR signals. An apparatus, based largely on conventional stopped-flow technology, is

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33

Li zhi Li and Han Ping Mao. "Design of multilayer microfluidic paper chip and its visual detection of pesticide residues." JOURNAL OF ADVANCES IN AGRICULTURE 11 (September 21, 2020): 170–82. http://dx.doi.org/10.24297/jaa.v11i.8861.

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With the increase of China's grain production, the use of pesticides is gradually increasing. Traditional pesticide detection takes a long time and requires expensive experimental instruments, which is not conducive to the rapid and accurate detection of pesticide residues in the field. To solve this problem, this paper proposes a visual detection method of pesticide residues based on multi-layer microfluidic paper chips. The internal channel structure of paper chip is designed from the perspective of efficient mixing. Through the simulation of the mixed effect of three kinds of staggered chan

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34

Rho, Hoon Suk, Henk-Willem Veltkamp, Alexander Thomas Hanke, et al. "Systematic Investigation of Insulin Fibrillation on a Chip." Molecules 25, no. 6 (2020): 1380. http://dx.doi.org/10.3390/molecules25061380.

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A microfluidic protein aggregation device (microPAD) that allows the user to perform a series of protein incubations with various concentrations of two reagents is demonstrated. The microfluidic device consists of 64 incubation chambers to perform individual incubations of the protein at 64 specific conditions. Parallel processes of metering reagents, stepwise concentration gradient generation, and mixing are achieved simultaneously by pneumatic valves. Fibrillation of bovine insulin was selected to test the device. The effect of insulin and sodium chloride (NaCl) concentration on the formatio

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35

McGann, Patrick T., Beverly A. Schaefer, Mary C. Paniagua, Thad A. Howard, and Russell E. Ware. "Accuracy of a Rapid and Simple Point-of-Care Test for Sickle Cell Disease." Blood 126, no. 23 (2015): 2182. http://dx.doi.org/10.1182/blood.v126.23.2182.2182.

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Abstract Sickle cell disease (SCD) is a common and life-threatening inherited disorder of hemoglobin, affecting over 400,000 newborns annually. The majority of these births occur in low-resource countries, particularly in sub-Saharan Africa, where limited access to accurate diagnostics results in early mortality. Accurate diagnosis of SCD currently relies upon analytical techniques that are relatively expensive and tedious, requiring equipment, electricity, and laboratory expertise. In Africa, outside of referral and regional hospitals, the availability of accurate SCD diagnostics is extremely

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Yan, Di, Qian Tang, Ahmed Kovacevic, et al. "Designing nano-aluminum laden fuel pump for aviation applications." Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering 234, no. 6 (2020): 634–43. http://dx.doi.org/10.1177/0954408920935315.

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In view of the fact that traditional liquid propellants cannot meet the design requirements of large-thrust flight vehicle, it has become a new trend to add nano-metal powder to liquid propellants to greatly increase density and specific impulse. In order to achieve the variable flow-rate and variable-proportion transportation of aviation fuel with nano-aluminum, a new type of solid-liquid mixing pumping system is designed, including powder conveying device, stirring device, pump and corresponding drive and transmission system. For the purpose of avoiding the frictional contact between the rot

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Monteiro, Diana C. F., Mohammad Vakili, Jessica Harich, et al. "A microfluidic flow-focusing device for low sample consumption serial synchrotron crystallography experiments in liquid flow." Journal of Synchrotron Radiation 26, no. 2 (2019): 406–12. http://dx.doi.org/10.1107/s1600577519000304.

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Serial synchrotron crystallography allows low X-ray dose, room-temperature crystal structures of proteins to be determined from a population of microcrystals. Protein production and crystallization is a non-trivial procedure and it is essential to have X-ray-compatible sample environments that keep sample consumption low and the crystals in their native environment. This article presents a fast and optimized manufacturing route to metal–polyimide microfluidic flow-focusing devices which allow for the collection of X-ray diffraction data in flow. The flow-focusing conditions allow for sample co

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Wang, Zhi Liang, Jian Gao, Chuan Xia Jian, Yao Cong Liang, and Yu Cen. "An Independent Component Analysis Based Defect Detection for the OLED Display." Advanced Materials Research 605-607 (December 2012): 724–28. http://dx.doi.org/10.4028/www.scientific.net/amr.605-607.724.

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Organic Light Emitting Displays (OLED) is a new type of display device which has become increasingly attractive and popular. Due to the complex manufacturing process, various defects may exist on the OLED panel. These defects have the characteristics of fuzzy boundaries, irregular in shape, low contrast with background and they are mixed with the texture background increasing the difficulty of a rapid identification. In this paper, we proposed an approach to detect these defects based on the model of independent component analysis (ICA). The ICA model is applied to a perfect OLED image to dete

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Knoll, G., C. Braun, and H. Plattner. "Quenched flow analysis of exocytosis in Paramecium cells: time course, changes in membrane structure, and calcium requirements revealed after rapid mixing and rapid freezing of intact cells." Journal of Cell Biology 113, no. 6 (1991): 1295–304. http://dx.doi.org/10.1083/jcb.113.6.1295.

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Synchronous exocytosis in Paramecium cells was analyzed on a subsecond time scale. For this purpose we developed a quenched flow device for rapid mixing and rapid freezing of cells without impairment (time resolution in the millisecond range, dead time approximately 30 ms). Cells frozen at defined times after stimulation with the noncytotoxic secretagogue aminoethyldextran were processed by freeze substitution for electron microscopic analysis. With ultrathin sections the time required for complete extrusion of secretory contents was determined to be less than 80 ms. Using freeze-fracture repl

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Ngo, H. H., S. Vigneswaran, and V. Jegatheesan. "Mathematical modelling of downflow floating medium filter (DFF) with in-line flocculation arrangement." Water Science and Technology 34, no. 3-4 (1996): 355–62. http://dx.doi.org/10.2166/wst.1996.0451.

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A laboratory-scale set-up consisting of rapid mixing device and floating medium filter was used to study the use of a downflow floating medium filter (DFF) with an in-line flocculation arrangement as a static flocculator and a prefilter. The semi-empirical mathematical model formulated incorporates flocculation within the filter, particle/floc attachment onto the filter and the detachment of flocs from the medium. The mathematical model for filtration takes into account the expansion of the filter bed. The removal efficiency of DFF and headloss development were successfully simulated for diffe

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Amalina, Auliya Nur, Veinardi Suendo, Muhammad Reza, et al. "Preparation of Polyaniline Emeraldine Salt for Conducting-Polymer-Activated Counter Electrode in Dye Sensitized Solar Cell (DSSC) using Rapid-Mixing Polymerization at Various Temperature." Bulletin of Chemical Reaction Engineering & Catalysis 14, no. 3 (2019): 521. http://dx.doi.org/10.9767/bcrec.14.3.3854.521-528.

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Polyaniline Emeraldine Salt (PANI ES) as a conductive polymer has been used as a Pt-free counter electrode materials in DSSC. In this study, polymerization temperature was varied at relatively high temperature from 308 to 348 K with respect to the standard low polymerization temperature at 273 K. The synthesis held in varied high-temperature to study the effect of synthesis condition resulted to the performance as counter electrode in DSSC. The effect of high-temperature synthesis condition gives interesting results, the FTIR-ATR spectra show the presence of vibrational modes of phenazine stru

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Zeng, Yushun, Laiming Jiang, Yizhe Sun, et al. "3D-Printing Piezoelectric Composite with Honeycomb Structure for Ultrasonic Devices." Micromachines 11, no. 8 (2020): 713. http://dx.doi.org/10.3390/mi11080713.

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Piezoelectric composites are considered excellent core materials for fabricating various ultrasonic devices. For the traditional fabrication process, piezoelectric composite structures are mainly prepared by mold forming, mixing, and dicing-filing techniques. However, these techniques are limited on fabricating shapes with complex structures. With the rapid development of additive manufacturing (AM), many research fields have applied AM technology to produce functional materials with various geometric shapes. In this study, the Mask-Image-Projection-based Stereolithography (MIP-SL) process, on

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Stoll, M. S., M. Sievers, C. Schroeder, and M. Niedermeiser. "Aggregate characterisation by using the FlocFormer system to improve sludge dewatering." Water Science and Technology 59, no. 10 (2009): 2009–15. http://dx.doi.org/10.2166/wst.2009.206.

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In this paper, the influence of the polymer-induced flocculation on undigested sludge dewatering is investigated by image analysis. The mixing of flocculants in a so-called rapid-mixer and the subsequent forming of aggregates is carried out by the FlocFormer system, a new sludge conditioning system. For the mechanical dewatering a decanter device is used. To evaluate the efficiency of the dewatering process, the total solid content (TS) of the dewatered sludge is analysed. The results of this study show that this type of flocculation represents an alternative to improve sludge dewatering of un

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Surendran, Vikram, Thomas Chiulli, Swetha Manoharan, Stephen Knisley, Muthukumaran Packirisamy, and Arvind Chandrasekaran. "Acoustofluidic Micromixing Enabled Hybrid Integrated Colorimetric Sensing, for Rapid Point-of-Care Measurement of Salivary Potassium." Biosensors 9, no. 2 (2019): 73. http://dx.doi.org/10.3390/bios9020073.

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The integration of microfluidics with advanced biosensor technologies offers tremendous advantages such as smaller sample volume requirement and precise handling of samples and reagents, for developing affordable point-of-care testing methodologies that could be used in hospitals for monitoring patients. However, the success and popularity of point-of-care diagnosis lies with the generation of instantaneous and reliable results through in situ tests conducted in a painless, non-invasive manner. This work presents the development of a simple, hybrid integrated optical microfluidic biosensor for

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Hoi, Pham Van, Nguyen Thuy Van, Pham Van Dai, Le Huu Thang, Nguyen Van An, and Pham Thanh Binh. "Wavelength Shift Measurement Method Without Use of Spectrometer: The New Way for Environment Photonic Sensors." Communications in Physics 28, no. 2 (2018): 139. http://dx.doi.org/10.15625/0868-3166/28/2/11040.

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The photonic sensors have shown very effectively for measuring the toxic contents in the liquid and air environments. In principle, the photonic sensors based on measurement of wavelength shift between reference condition and testing environments that we need use the spectrometer with high cost. In this paper, we present new configurations of photonic devices for measuring wavelength shift without use of spectrometer, which has a large potential for application in sensing technique with low cost. There are two configurations of photonic sensors are presented: i) first of them is based on fiber

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Zhu, Cancan, Anzhong Hu, Junsheng Cui, et al. "A Lab-on-a-Chip Device Integrated DNA Extraction and Solid Phase PCR Array for the Genotyping of High-Risk HPV in Clinical Samples." Micromachines 10, no. 8 (2019): 537. http://dx.doi.org/10.3390/mi10080537.

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Point-of-care (POC) molecular diagnostics play a crucial role in the prevention and treatment of infectious diseases. It is necessary to develop portable, easy-to-use, inexpensive and rapid molecular diagnostic tools. In this study, we proposed a lab-on-a-chip device that integrated DNA extraction, solid-phase PCR and genotyping detection. The ingenious design of the pneumatic microvalves enabled the fluid mixing and reagent storage to be organically combined, significantly reducing the size of the chip. The solid oligonucleotide array incorporated into the chip allowed the spatial separation

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Tashjian, A. H., J. P. Heslop, and M. J. Berridge. "Subsecond and second changes in inositol polyphosphates in GH4C1 cells induced by thyrotropin-releasing hormone." Biochemical Journal 243, no. 1 (1987): 305–8. http://dx.doi.org/10.1042/bj2430305.

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It has been demonstrated previously that thyrotropin-releasing hormone (TRH) induces changes in inositol polyphosphates in the GH3 and GH4C1 strains of rat pituitary cells within 2.5-5.0 s. TRH also causes a rapid rise in cytosolic free calcium concentration ([Ca2+]i) in these cells which is due largely to redistribution of cellular calcium stores. Therefore, it has been concluded that TRH acts to release sequestered calcium in these cells via enhanced generation of inositol 1,4,5-trisphosphate [Ins(1,4,5)P3]. If this conclusion were correct, TRH-enhanced accumulation of Ins(1,4,5)P3 should oc

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Kim, Young Ho, Jeong Woo Sohn, Youngjae Woo, Joo Hyun Hong, and Juyoung Park. "Fabrication of PEG Hydrogel and PDMS Microstructures by a Simple UV Curing Process for Nanobio-Chip Applications." Advanced Materials Research 941-944 (June 2014): 404–10. http://dx.doi.org/10.4028/www.scientific.net/amr.941-944.404.

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Polyethylene glycol (PEG) hydrogel microstructures with various shapes and sizes on a glass chip were prepared by a simple and rapid ultraviolet (UV) irradiation method using a metal mask. Photocurable PEG solution prepared by mixing 95 wt.% polyethylene glycol diacrylate and 5 wt.% 2-hydroxy-2-methylpropiophenone as a photo-initiator was injected to the gap between bottom and upper glasses in a simply assembled glass chip. After a metal mask with line-and-space or complex patterns was placed on the glass chip, UV light from a spot UV irradiation device was exposed to the glass chip through th

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Paterson, Thomas E., Rui Shi, Jingjing Tian, et al. "Electrospun Scaffolds Containing Silver-Doped Hydroxyapatite with Antimicrobial Properties for Applications in Orthopedic and Dental Bone Surgery." Journal of Functional Biomaterials 11, no. 3 (2020): 58. http://dx.doi.org/10.3390/jfb11030058.

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Preventing the development of osteomyelitis while enhancing bone regeneration is challenging, with relatively little progress to date in translating promising technologies to the clinic. Nanoscale hydroxyapatite (nHA) has been employed as a bone graft substitute, and recent work has shown that it may be modified with silver to introduce antimicrobial activity against known pathogens. The aim of this study was to incorporate silver-doped nHA into electrospun scaffolds for applications in bone repair. Silver-doped nHA was produced using a modified, rapid mixing, wet precipitation method at 2, 5,

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Blanchet, Clement E., Alessandro Spilotros, Frank Schwemmer, et al. "Versatile sample environments and automation for biological solution X-ray scattering experiments at the P12 beamline (PETRA III, DESY)." Journal of Applied Crystallography 48, no. 2 (2015): 431–43. http://dx.doi.org/10.1107/s160057671500254x.

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A high-brilliance synchrotron P12 beamline of the EMBL located at the PETRA III storage ring (DESY, Hamburg) is dedicated to biological small-angle X-ray scattering (SAXS) and has been designed and optimized for scattering experiments on macromolecular solutions. Scatterless slits reduce the parasitic scattering, a custom-designed miniature active beamstop ensures accurate data normalization and the photon-counting PILATUS 2M detector enables the background-free detection of weak scattering signals. The high flux and small beam size allow for rapid experiments with exposure time down to 30–50

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