Academic literature on the topic 'Rare codon'

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Journal articles on the topic "Rare codon"

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Hu, Xiao Huan, Ming Shu Wang, and An Chun Cheng. "Analysis of Synonymous Codon Usage in the US5 Gene of Duck Plague Virus." Advanced Materials Research 641-642 (January 2013): 606–14. http://dx.doi.org/10.4028/www.scientific.net/amr.641-642.606.

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The Duck Plague Virus (DPV) US5 gene was identified by constructing the DPV genomic library, the synonymous codon usage in the US5 gene of DPV and 11 reference herpesviruses have been investigated by using the CodonW 1.4 program, CUSP (create a codon usage table) program and CHIPS (calculated ENC value) of EMBOSS (The European Molecular Biology Open Software Suite). The results reveals that the synonymous codons with A and T at the third codon positon have widely usage in the codon of US5 gene of DPV. G + C compositional constraint is the main factor that determines the codon usage bias in US5
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Yang, Qian, Chien-Hung Yu, Fangzhou Zhao, et al. "eRF1 mediates codon usage effects on mRNA translation efficiency through premature termination at rare codons." Nucleic Acids Research 47, no. 17 (2019): 9243–58. http://dx.doi.org/10.1093/nar/gkz710.

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Abstract Codon usage bias is a universal feature of eukaryotic and prokaryotic genomes and plays an important role in regulating gene expression levels. A major role of codon usage is thought to regulate protein expression levels by affecting mRNA translation efficiency, but the underlying mechanism is unclear. By analyzing ribosome profiling results, here we showed that codon usage regulates translation elongation rate and that rare codons are decoded more slowly than common codons in all codon families in Neurospora. Rare codons resulted in ribosome stalling in manners both dependent and ind
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Newaz, Khalique, Gabriel Wright, Jacob Piland, et al. "Network analysis of synonymous codon usage." Bioinformatics 36, no. 19 (2020): 4876–84. http://dx.doi.org/10.1093/bioinformatics/btaa603.

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Abstract Motivation Most amino acids are encoded by multiple synonymous codons, some of which are used more rarely than others. Analyses of positions of such rare codons in protein sequences revealed that rare codons can impact co-translational protein folding and that positions of some rare codons are evolutionarily conserved. Analyses of their positions in protein 3-dimensional structures, which are richer in biochemical information than sequences alone, might further explain the role of rare codons in protein folding. Results We model protein structures as networks and use network centralit
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Fu, Jingjing, Yunkun Dang, Christopher Counter, and Yi Liu. "Codon usage regulates human KRAS expression at both transcriptional and translational levels." Journal of Biological Chemistry 293, no. 46 (2018): 17929–40. http://dx.doi.org/10.1074/jbc.ra118.004908.

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KRAS and HRAS are highly homologous oncogenic Ras GTPase family members that are mutated in a wide spectrum of human cancers. Despite having high amino acid identity, KRAS and HRAS have very different codon usage biases: the HRAS gene contains many common codons, and KRAS is enriched for rare codons. Rare codons in KRAS suppress its protein expression, which has been shown to affect both normal and cancer biology in mammals. Here, using HRAS or KRAS expression in different human cell lines and in vitro transcription and translation assays, we show that KRAS rare codons inhibit both translation
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D’Andrea, Lucía, Francisco-Javier Pérez-Rodríguez, Montserrat de Castellarnau, et al. "The Critical Role of Codon Composition on the Translation Efficiency Robustness of the Hepatitis A Virus Capsid." Genome Biology and Evolution 11, no. 9 (2019): 2439–56. http://dx.doi.org/10.1093/gbe/evz146.

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AbstractHepatoviruses show an intriguing deviated codon usage, suggesting an evolutionary signature. Abundant and rare codons in the cellular genome are scarce in the human hepatitis A virus (HAV) genome, while intermediately abundant host codons are abundant in the virus. Genotype–phenotype maps, or fitness landscapes, are a means of representing a genotype position in sequence space and uncovering how genotype relates to phenotype and fitness. Using genotype–phenotype maps of the translation efficiency, we have shown the critical role of the HAV capsid codon composition in regulating transla
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Napolitano, Michael G., Matthieu Landon, Christopher J. Gregg, et al. "Emergent rules for codon choice elucidated by editing rare arginine codons in Escherichia coli." Proceedings of the National Academy of Sciences 113, no. 38 (2016): E5588—E5597. http://dx.doi.org/10.1073/pnas.1605856113.

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The degeneracy of the genetic code allows nucleic acids to encode amino acid identity as well as noncoding information for gene regulation and genome maintenance. The rare arginine codons AGA and AGG (AGR) present a case study in codon choice, with AGRs encoding important transcriptional and translational properties distinct from the other synonymous alternatives (CGN). We created a strain of Escherichia coli with all 123 instances of AGR codons removed from all essential genes. We readily replaced 110 AGR codons with the synonymous CGU codons, but the remaining 13 “recalcitrant” AGRs required
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Bakli, Mahfoud, Raul Pascalau, and Laura Smuleac. "Rare Codon Analysis in Rickettsia Affecting Recombinant Protein Expression in Escherichia coli." Advanced Research in Life Sciences 4, no. 1 (2020): 30–35. http://dx.doi.org/10.2478/arls-2020-0015.

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Abstract Rickettsia species are important emerging pathogens causing rickettsial diseases, which are important cause death worldwide. The number of recombinant proteins used for diagnostic and therapeutic applications has increased dramatically, which is important in determination of protein function, structure and antigensity. Although E. coli is widely used expression system, the codon bias can hamper protein expression due to the presence of rare codons in gene sequence coding protein of interest. Using bioinformatics tools, rare codon analysis of rickettsial genes was performed and compare
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Kanduc, Darja. "Rare Human Codons and HCMV Translational Regulation." Journal of Molecular Microbiology and Biotechnology 27, no. 4 (2017): 213–16. http://dx.doi.org/10.1159/000478093.

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Restriction of protein synthesis characterizes human cytomegalovirus (HCMV) latency in the human host. In analyzing the molecular factors that hinder HCMV expression, the present study shows that HCMV genes frequently use 6 rare codons, i.e., GCG (Ala), CCG (Pro), CGT (Arg), CGC (Arg), TCG (Ser), and ACG (Thr). In some instances, the rare host codons are clustered along viral nucleotide sequences and represent the majority in sequences encoding short alanine and proline repeats. Given the positive correlation between codon usage, tRNA content, and protein production, the results support the hy
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Lee, Song F., Yi-Jing Li, and Scott A. Halperin. "Overcoming codon-usage bias in heterologous protein expression in Streptococcus gordonii." Microbiology 155, no. 11 (2009): 3581–88. http://dx.doi.org/10.1099/mic.0.030064-0.

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One of the limitations facing the development of Streptococcus gordonii into a successful vaccine vector is the inability of this bacterium to express high levels of heterologous proteins. In the present study, we have identified 12 codons deemed as rare codons in S. gordonii and seven other streptococcal species. tRNA genes encoding 10 of the 12 rare codons were cloned into a plasmid. The plasmid was transformed into strains of S. gordonii expressing the fusion protein SpaP/S1, the anti-complement receptor 1 (CR1) single-chain variable fragment (scFv) antibody, or the Toxoplasma gondii cyclop
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Frumkin, Idan, Marc J. Lajoie, Christopher J. Gregg, Gil Hornung, George M. Church, and Yitzhak Pilpel. "Codon usage of highly expressed genes affects proteome-wide translation efficiency." Proceedings of the National Academy of Sciences 115, no. 21 (2018): E4940—E4949. http://dx.doi.org/10.1073/pnas.1719375115.

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Although the genetic code is redundant, synonymous codons for the same amino acid are not used with equal frequencies in genomes, a phenomenon termed “codon usage bias.” Previous studies have demonstrated that synonymous changes in a coding sequence can exert significantciseffects on the gene’s expression level. However, whether the codon composition of a gene can also affect the translation efficiency of other genes has not been thoroughly explored. To study how codon usage bias influences the cellular economy of translation, we massively converted abundant codons to their rare synonymous cou
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Dissertations / Theses on the topic "Rare codon"

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Tegel, Hanna. "Proteome wide protein production." Doctoral thesis, KTH, Proteomik och nanobioteknologi, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-134215.

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Over a decade after the completion of the human genome, researchers around the world are still wondering what information is hidden in the genome. Although the sequences of all human genes are known, it is still almost impossible to determine much more than the primary protein structure from the coding sequence of a gene. As a result of that, the need for recombinantly produced proteins to study protein structure and function is greater than ever. The main objective of this thesis has been to improve protein production, particularly using Escherichia coli. To improve protein production in Esch
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Gueguen, Erwan. "Étude de la thermosensibilité de transposition de la séquence d'insertion bactérienne IS911." Toulouse 3, 2006. http://www.theses.fr/2006TOU30183.

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Harrison, C. J. "The role of rare codons in protein expression." Thesis, University College London (University of London), 2015. http://discovery.ucl.ac.uk/1469916/.

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That the flow of information from gene sequence to protein sequence depends on the translation of a code that could literally be described as digital is a truly incredible feat of nature. However, the process of translation is a noisy, stochastic, kinetic process that depends on many factors. The redundancy in the genetic code allows the transmission of additional, analogue information by varying some of these factors. How organisms use the redundancy is termed codon usage, and rare codons are those that are typically shunned in favour of other synonymous options. Synonymous variations to the
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Sjövall, Annika. "Colon cancer : management and outcome in a Swedish populaiton /." Stockholm, 2007. http://diss.kib.ki.se/2007/978-91-7357-062-6/.

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Mantzaris, Alexander Vassilios. "Improved Bayesian methods for detecting recombination and rate heterogeneity in DNA sequence alignments." Thesis, University of Edinburgh, 2011. http://hdl.handle.net/1842/5735.

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DNA sequence alignments are usually not homogeneous. Mosaic structures may result as a consequence of recombination or rate heterogeneity. Interspecific recombination, in which DNA subsequences are transferred between different (typically viral or bacterial) strains may result in a change of the topology of the underlying phylogenetic tree. Rate heterogeneity corresponds to a change of the nucleotide substitution rate. Various methods for simultaneously detecting recombination and rate heterogeneity in DNA sequence alignments have recently been proposed, based on complex probabilistic models t
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Choudhary, Bhavesh [Verfasser]. "Effect of MMR status and growth rate of colon carcinoma cells in response to 5-fluorouracil / Bhavesh Choudhary." Berlin : Freie Universität Berlin, 2011. http://d-nb.info/102551100X/34.

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Mugal, Carina Farah. "Nucleotide Substitution Patterns in Vertebrate Genomes." Doctoral thesis, Uppsala universitet, Evolutionsbiologi, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-198787.

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The rates and patterns at which nucleotide substitutions occur vary significantly across the genome sequence of vertebrates. A prominent example is the difference in the rate of evolution of functional sequences versus nonfunctional (neutrally evolving) sequences, which is explained by the influence of natural selection on functional sequences. However, even within neutrally evolving sequences there is striking variation in the rates and patterns of nucleotide substitutions. Unraveling the underlying processes that induce this variation is necessary to understand the basic principles of variat
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Szathmary, Laszlo. "Méthodes symboliques de fouille de données avec la plate-forme Coron." Phd thesis, Université Henri Poincaré - Nancy I, 2006. http://tel.archives-ouvertes.fr/tel-00336374.

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Le sujet principal de cette thèse est l'extraction de connaissances dans les bases de données (ECBD). Plus précisément, nous avons étudié deux des plus importantes tâches d'ECBD actuelles, qui sont l'extraction de motifs et la génération de règles d'association. Tout au long de notre travail, notre objectif a été de trouver des règles d'associations intéressantes selon plusieurs points de vue : dans un but de fouille efficace, pour réduire au minimum l'ensemble des règles extraites et pour trouver des unités de connaissances intelligibles (et facilement interprétables). Pour atteindre ce but,
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Benhabiles, Hana. "Etude de la correction de mutations non sens par de nouvelles molécules pouvant servir d'approches thérapeutiques ciblées." Thesis, Lille 2, 2017. http://www.theses.fr/2017LIL2S046.

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Les mutations non sens introduisent un codon stop prématuré dans une phase ouverte de lecture. Ce type de mutation est retrouvé chez environ 11% des patients atteints de maladies génétiques et dans de nombreux cancers. En effet, entre 5 et 40% des mutations affectant des gènes suppresseurs de tumeurs sont des mutations non sens. La conséquence de la présence d’une mutation non sens dans un gène est la dégradation rapide de l’ARN messager correspondant, par l’activation d’un mécanisme de surveillance des ARN appelé NMD (pour nonsense-mediated mRNA decay) conduisant à une absence d’expression du
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Ehrensberger, Ryan J. "Modeling Racial Differences in Colorectal Cancer Screening: Evidence from a Nationally Representative Sample." VCU Scholars Compass, 2007. https://digarchive.library.vcu.edu/handle/10156/1507.

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Books on the topic "Rare codon"

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James, Miranda. Classified as murder. Berkley Prime Crime, 2011.

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Cordon bleu (School : Paris, France), ed. The sharper your knife, the less you cry: Love, learning and tears at the world's most famous cooking school. Viking, 2007.

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Cordon bleu (School : Paris, France), ed. The sharper your knife, the less you cry: Love, laughter, and tears in Paris at the world's most famous cooking school. Penguin, 2008.

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Flinn, Kathleen. The Slave Ship. Penguin Group (USA), Inc., 2008.

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Walsh, Bruce, and Michael Lynch. Using Molecular Data to Detect Selection: Signatures from Multiple Historical Events. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198830870.003.0010.

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This chapter examines the search for a pattern of repetitive adaptive substitutions over evolutionary time. In contrast with the previous chapter, only a modest number of tests toward this aim have been proposed. The HKA and McDonald-Kreitman tests contrast the polymorphism to divergence ratio between different genomic classes (such as different genes or silent versus replacement sites within the same gene). These approaches can detect an excess of substitutions, which allows one to estimate the fraction of adaptive sites. This chapter reviews the empirical data on estimates of this fraction a
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Ammen, Sharon. The “Only One Boss Bully”. University of Illinois Press, 2017. http://dx.doi.org/10.5406/illinois/9780252040658.003.0005.

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Chapter four continues the examination of the coon song begun in chapter three, narrowing the focus to Irwin’s two most popular songs, “The Frog Song” and “The Bully.” The author analyzes the differing responses of black and white audiences to the coon song and the accompanying cakewalk. She discusses the case of black female coon shouters, such as Belle Davis, who parody May Irwin’s style of singing. The author looks at Irwin as a white mammy figure and delves into the layers of meaning inherent in her performance of the Bully, layers that reveal the intersection of racism and misogyny; the i
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Keshav, Satish, and Palak Trivedi. Liver cancer. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0218.

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Primary hepatocellular carcinoma (HCC) arises from hepatocytes and is one of the commonest solid-organ malignancies in the world, particularly in the Far East and in sub-Saharan Africa. Cholangiocarcinoma arises from the biliary epithelium. The incidence is rising in the West, and primary sclerosing cholangitis (PSC) is an important risk factor (15% lifetime risk). Other forms of liver cancer include metastatic cancer, which is much more common in the West than any primary liver cancer, accounting for 90% of liver cancers and for which common primary sites are the colon, the stomach, the breas
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Flinn, Kathleen. Sharper Your Knife, the Less You Cry: Love, Laughter and Tears at the World's Most Famous Cooking School. Little, Brown Book Group Limited, 2008.

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The Sharper Your Knife, the Less You Cry: Love, Laughter, and Tears at the World's Most Famous Cooking School. Viking Adult, 2007.

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Flinn, Kathleen. The Sharper Your Knife, the Less You Cry: Love, Laughter, and Tears at the World's Most Famous Cooking School. Penguin Audio, 2007.

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Book chapters on the topic "Rare codon"

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McNulty, Dean E., Michael J. Huddleston, Brett Claffee, et al. "Translational Problems Associated with the Rare Arginine Codon CGG in Escherichia Coli." In Recombinant Protein Production with Prokaryotic and Eukaryotic Cells. A Comparative View on Host Physiology. Springer Netherlands, 2001. http://dx.doi.org/10.1007/978-94-015-9749-4_12.

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Skronski, Michal, Joanna Chorostowska-Wynimko, Ewa Szczepulska, et al. "Reliable Detection of Rare Mutations in EGFR Gene Codon L858 by PNA-LNA PCR Clamp in Non-small Cell Lung Cancer." In Advances in Experimental Medicine and Biology. Springer Netherlands, 2012. http://dx.doi.org/10.1007/978-94-007-4549-0_39.

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Papadopoulos, Vasilios, and Konstantinos Triantafyllou. "Methods to Improve the Adenoma Detection Rate." In Colon Polypectomy. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-59457-6_2.

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Condon, E. U., and P. E. Condon. "Effect of Oscillations of the Case on the Rate of a Watch." In Selected Popular Writings of E.U. Condon. Springer New York, 1991. http://dx.doi.org/10.1007/978-1-4612-3066-3_25.

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Mantzaris, Alexander V., and Dirk Husmeier. "Distinguishing Regional from Within-Codon Rate Heterogeneity in DNA Sequence Alignments." In Pattern Recognition in Bioinformatics. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-04031-3_17.

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Nishioka, Hirotaka, Akihiro Kimura, Takahisa Yamato, and Toshiaki Kakitani. "Non-Condon Theory for the Energy Gap Dependence of Electron Transfer Rate." In Frontiers of Computational Science. Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-46375-7_44.

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Takahashi, Takashi, and Tamaki Kajitani. "Considerations on Recent Improvements in Five-Year Survival Rate of Colon and Rectal Cancer." In Digestive Tract Tumors. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-5149-8_23.

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Sørensen, Michael A., Kaj Frank Jensen, and Steen Pedersen. "Measurement of translation rates in vivo at individual codons and implication of these rate differences for gene expression." In Post-Transcriptional Control of Gene Expression. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-75139-4_20.

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"RARE TUMOURS OF THE COLON AND RECTUM." In Surgery of the Anus, Rectum & Colon. Elsevier, 2008. http://dx.doi.org/10.1016/b978-0-7020-2723-9.50037-3.

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Stanojevi, Goran, and Zoran Krivokapi. "Rare Tumors of the Colon and Rectum." In Colorectal Cancer - Surgery, Diagnostics and Treatment. InTech, 2014. http://dx.doi.org/10.5772/56937.

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Conference papers on the topic "Rare codon"

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Miller, Jason E., Manu K. Shivakumar, Shannon L. Risacher, et al. "Codon bias among synonymous rare variants is associated with Alzheimer’s disease imaging biomarker." In Pacific Symposium on Biocomputing 2018. WORLD SCIENTIFIC, 2017. http://dx.doi.org/10.1142/9789813235533_0034.

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Graham, J. B., D. B. Lubahn, J. D. Kirshtein, et al. "THE “MALMO“ EPITOPE OF FACTOR IX: PHENOTYPIC EXPRESSION OF THE “VIKING“ GENE." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643566.

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The epitope of a mouse monoclonal AB (9.9) which detects a Factor IX (F.IX) polymorphism in the plasma of normal persons (PNAS 82:3839, 1985) has been related to not more than 6 AA residues of F.IX by recombinant DNA technology. The same 6 residues define Smith’s polymorphic epitope (Am. J. Human Genet. 37:688, 1985 and in press). This region of F.IX contains the alanine:threonine dimorphism at residue 148 first suggested by McGraw et al. (PNAS 82: 2847, 1985) and established by Winship and Brownlee with synthetic DNA oligomers (Lancet in press). Using synthetic DNA probes, we have found that
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Gavalis, Robb M., Hua Xing, Peter Y. Wong, Lothar Lilge, and Caroline G. L. Cao. "Design of a Navigational Aid for Colonoscopy." In ASME 2008 3rd Frontiers in Biomedical Devices Conference. ASMEDC, 2008. http://dx.doi.org/10.1115/biomed2008-38060.

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Colonoscopy is currently the gold standard for diagnosing colorectal cancer and inflammatory bowel disease. During a colonoscopy, a flexible endoscope is inserted into the patient’s colon to inspect the inner wall of the large intestine, from the rectum to the caecum. This procedure is very important for cancer screening and can yield early diagnosis. Colon cancer is 85–95% successfully treated if detected early; however, there is only a 30% compliance rate for the procedure in the United States. This low compliance rate for the examination is largely due to its uncomfortable nature, caused by
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Pershing, Nicole L. K., Benjamin L. Lampson, and Christopher M. Counter. "Abstract IA14: Rare codons capacitate Kras-driven de novo tumorigenesis." In Abstracts: AACR Special Conference on Translational Control of Cancer: A New Frontier in Cancer Biology and Therapy; October 27-30, 2016; San Francisco, CA. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.transcontrol16-ia14.

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Gavalis, Robb M., Hua Xing, Peter Y. Wong, Lothar Lilge, and Caroline G. L. Cao. "Endoscope Shape-Tracker Based on Embedded Fluorescent Dyes in an Optical Fiber." In ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-192809.

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Endoscopes are used in medicine to inspect inside the body without having to perform open surgery on the patient. The current gold standard for screening and diagnosing colorectal cancer and inflammatory bowel disease is the colonoscopy. This procedure uses a flexible endoscope to inspect the wall of the large intestine, from the rectum to the caecum, for cancerous or precancerous lesions. This screening is very important since early detection of colon cancer is 85–95% successfully treated. Unfortunately, there is only a 30% compliance rate for colonoscopies in the United States. This lack of
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Hasanova, S. Y. k. "To the question of the treatment of pancreatic necrosis." In General question of world science. Наука России, 2021. http://dx.doi.org/10.18411/gq-31-07-2021-06.

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The results of surgical treatment of pancreatic necrosis using stem cells, the structure of mortality and complications for the period 2013-2019 were analyzed. It has been shown that the use of cordon blood stem cells after laparotomy in the treatment of pancreatic necrosis can reduce the mortality rate associated with complications of infected pancreatic necrosis and improve the overall results of treatment of acute pancreatitis.
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Tiwari, Alok, Dhananjay Gughe, Radhika Dureja, and Satinder Kaur. "Synchronous primary malignancy of ovary and cervix with different histopathology: A rare case report." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685388.

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Concurrent different histopathological types of gynecologic tumors arise rarely. We present ovarian serous and cervical squamous cell carcinoma formed synchronously. A 51-year-old woman with a poor general condition was admitted with gradual distension of abdomen for 1 year with gradual loss of weight and appetite for the last three months and pain in the abdomen and irregular vaginal bleeding for the last two months. There was no family history of malignancy of genital tract, breast or colon. On examination she was cachexic, pale, dehydrated, tachypnoeic and had edema over feet. Per abdomen e
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Bisht, Jyoti, Ravi Kant, Meenu Gupta, et al. "Dosimetric evaluation of sigmoidal and bowel doses in the treatment of carcinoma of cervix using CT based volumetric imaging technique." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685397.

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Purpose: Radiation therapy is the main stray for the treatment of the cervical cancer. Normal organs such as bladder, rectum, sigmoid colon and bowel loops also get significant dose during treatment of carcinoma of cervix which often results late toxicity. The purpose of this study is evaluate CT image based volumetric doses of organ at risk and correlate the doses with the toxicity profile observed in cancer patients. Materials and Methods: Sixty high dose rate intracavitary brachytherapy applications were performed in thirty patients of carcinoma of cervix. External beam therapy was planned
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Semenov, S., Ismail MS, F. O’Hara, et al. "The True False Negative Rate of Colon Capsule Endoscopy is Low." In ESGE Days 2021. Georg Thieme Verlag KG, 2021. http://dx.doi.org/10.1055/s-0041-1724516.

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Doong, Howard, Xiaofei Li, Caifu Chen, and Julian Walker. "Abstract LB-222: Identification of rare KRAS codons 12 and 13 mutations by shifted termination assay." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-lb-222.

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