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Relevant bibliographies by topics / Rare codon / Dissertations / Theses

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Dissertations / Theses on the topic 'Rare codon'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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1

Tegel, Hanna. "Proteome wide protein production." Doctoral thesis, KTH, Proteomik och nanobioteknologi, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-134215.

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Over a decade after the completion of the human genome, researchers around the world are still wondering what information is hidden in the genome. Although the sequences of all human genes are known, it is still almost impossible to determine much more than the primary protein structure from the coding sequence of a gene. As a result of that, the need for recombinantly produced proteins to study protein structure and function is greater than ever. The main objective of this thesis has been to improve protein production, particularly using Escherichia coli. To improve protein production in Esch

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2

Gueguen, Erwan. "Étude de la thermosensibilité de transposition de la séquence d'insertion bactérienne IS911." Toulouse 3, 2006. http://www.theses.fr/2006TOU30183.

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3

Harrison, C. J. "The role of rare codons in protein expression." Thesis, University College London (University of London), 2015. http://discovery.ucl.ac.uk/1469916/.

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That the flow of information from gene sequence to protein sequence depends on the translation of a code that could literally be described as digital is a truly incredible feat of nature. However, the process of translation is a noisy, stochastic, kinetic process that depends on many factors. The redundancy in the genetic code allows the transmission of additional, analogue information by varying some of these factors. How organisms use the redundancy is termed codon usage, and rare codons are those that are typically shunned in favour of other synonymous options. Synonymous variations to the

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4

Sjövall, Annika. "Colon cancer : management and outcome in a Swedish populaiton /." Stockholm, 2007. http://diss.kib.ki.se/2007/978-91-7357-062-6/.

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5

Mantzaris, Alexander Vassilios. "Improved Bayesian methods for detecting recombination and rate heterogeneity in DNA sequence alignments." Thesis, University of Edinburgh, 2011. http://hdl.handle.net/1842/5735.

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DNA sequence alignments are usually not homogeneous. Mosaic structures may result as a consequence of recombination or rate heterogeneity. Interspecific recombination, in which DNA subsequences are transferred between different (typically viral or bacterial) strains may result in a change of the topology of the underlying phylogenetic tree. Rate heterogeneity corresponds to a change of the nucleotide substitution rate. Various methods for simultaneously detecting recombination and rate heterogeneity in DNA sequence alignments have recently been proposed, based on complex probabilistic models t

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6

Choudhary, Bhavesh [Verfasser]. "Effect of MMR status and growth rate of colon carcinoma cells in response to 5-fluorouracil / Bhavesh Choudhary." Berlin : Freie Universität Berlin, 2011. http://d-nb.info/102551100X/34.

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7

Mugal, Carina Farah. "Nucleotide Substitution Patterns in Vertebrate Genomes." Doctoral thesis, Uppsala universitet, Evolutionsbiologi, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-198787.

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The rates and patterns at which nucleotide substitutions occur vary significantly across the genome sequence of vertebrates. A prominent example is the difference in the rate of evolution of functional sequences versus nonfunctional (neutrally evolving) sequences, which is explained by the influence of natural selection on functional sequences. However, even within neutrally evolving sequences there is striking variation in the rates and patterns of nucleotide substitutions. Unraveling the underlying processes that induce this variation is necessary to understand the basic principles of variat

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8

Szathmary, Laszlo. "Méthodes symboliques de fouille de données avec la plate-forme Coron." Phd thesis, Université Henri Poincaré - Nancy I, 2006. http://tel.archives-ouvertes.fr/tel-00336374.

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Le sujet principal de cette thèse est l'extraction de connaissances dans les bases de données (ECBD). Plus précisément, nous avons étudié deux des plus importantes tâches d'ECBD actuelles, qui sont l'extraction de motifs et la génération de règles d'association. Tout au long de notre travail, notre objectif a été de trouver des règles d'associations intéressantes selon plusieurs points de vue : dans un but de fouille efficace, pour réduire au minimum l'ensemble des règles extraites et pour trouver des unités de connaissances intelligibles (et facilement interprétables). Pour atteindre ce but,

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9

Benhabiles, Hana. "Etude de la correction de mutations non sens par de nouvelles molécules pouvant servir d'approches thérapeutiques ciblées." Thesis, Lille 2, 2017. http://www.theses.fr/2017LIL2S046.

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Les mutations non sens introduisent un codon stop prématuré dans une phase ouverte de lecture. Ce type de mutation est retrouvé chez environ 11% des patients atteints de maladies génétiques et dans de nombreux cancers. En effet, entre 5 et 40% des mutations affectant des gènes suppresseurs de tumeurs sont des mutations non sens. La conséquence de la présence d’une mutation non sens dans un gène est la dégradation rapide de l’ARN messager correspondant, par l’activation d’un mécanisme de surveillance des ARN appelé NMD (pour nonsense-mediated mRNA decay) conduisant à une absence d’expression du

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10

Ehrensberger, Ryan J. "Modeling Racial Differences in Colorectal Cancer Screening: Evidence from a Nationally Representative Sample." VCU Scholars Compass, 2007. https://digarchive.library.vcu.edu/handle/10156/1507.

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11

Jacinto, Andreia Grangeiro. "Rastreio parasitológico de Tritrichomonas foetus em gatos." Master's thesis, Universidade de Lisboa, Faculdade de Medicina Veterinária, 2016. http://hdl.handle.net/10400.5/12383.

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Dissertação de Mestrado Integrado em Medicina Veterinária<br>A tritrichomonose felina é uma doença parasitária provocada pelo protozoário flagelado Tritrichomonas foetus, por vezes, também, designado por T. blagburni. Esta parasitose está associada a uma diarreia crónica ou intermitente com origem no intestino grosso, porém alguns dos animais parasitados não apresentam sinais clínicos. Está descrito que gatos jovens (<12 meses), que vivam em ambientes com mais do que um gato e que sejam de raça pura apresentem uma maior suscetibilidade de contraírem esta parasitose. Nos últimos anos têm sido

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12

Almonte, Michelle. "History, Material Culture, and the Search for the Mythic American Dream in Angie Cruz’s Let it Rain Coffee." FIU Digital Commons, 2017. http://digitalcommons.fiu.edu/etd/3175.

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This thesis examines the connection between Dominican history, the influence of American material culture, and the mythic American Dream as catalysts for migration. The two U.S. occupations and American propaganda through media had a great effect on the deceptive perception of an American life as an effortless method for attaining wealth. Let it Rain Coffee by Angie Cruz, will focus on the character, Esperanza Colon, and her obsession with the lavish lifestyle she views on the television show, Dallas. Material objects, as argued by Daniel Miller in his book, Stuff, work in subtle yet significa

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13

Garabedian, Charles. "Développement d’un nouvel indice reflet du bien être fœtal : le Fetal Stress Index." Thesis, Lille 2, 2017. http://www.theses.fr/2017LIL2S022/document.

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La surveillance du bien-être fœtal pendant le travail repose essentiellement sur l’enregistrement du rythme cardiaque fœtal (RCF). Celui-ci, même continu pendant le travail, ne permet pas d’évaluer parfaitement l’oxygénation du fœtus ni le risque d’asphyxie néonatale. En effet, cet outil est imparfait et son évaluation subjective avec une importante variabilité d’interprétation inter et intra opérateur. Des examens dits de seconde ligne sont utilisés en pratique courante pour caractériser l’état fœtal : le prélèvement de sang fœtal au scalp pour l’étude de l’équilibre acido-basique du fœtus (p

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14

Clarke, Thomas Francis. "Rare codon clusters enrichment, functional effects, non-random localization and conservation /." 2009. http://etd.nd.edu/ETD-db/theses/available/etd-12172009-210540/.

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Thesis (Ph. D.)--University of Notre Dame, 2009.<br>Thesis directed by Patricia L. Clark for the Department of Chemistry and Biochemistry. "December 2009." Includes bibliographical references (leaves 84-88).

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15

Yorke, Adam F. "Effects of codon utilization rate on the synthesis of recombinant proteins in Escherichia coli /." Diss., 2001. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3010437.

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16

Wu, Yu-Hua, and 吳育樺. "ROLES OF ADVANCED GLYCATION END PRODUCTS (AGE) AND RECEPTOR FOR AGE (RAGE) IN CELL GROWTH IN HUMAN COLON CANCER." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/07082690621681571864.

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碩士<br>中華醫事科技大學<br>生物科技系暨生物醫學研究所<br>102<br>Mounting evidence indicates that advanced glycation end-products (AGE) and their receptors (RAGE) have been implicated in tumor development and metastatic progression. However, prospective data on their association with cancer of specific sites, including colorectal cancer, are limited. We examined here whether and how AGE/RAGE could regulate cell growth in human colorectal adenocarcinoma cell lines (HT-29 and SW-480). We found that exposure of HT-29 and SW-480 cells to AGE (but not non-glycated BSA) increased the cell growth in concentration- and time

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17

Elshikh, Ahmed Fahmy Mahoud Aly, and 和平. "Effects Of Probiotics Isolated From Commercial Denitrification Product And Penaeus Monodon Colon On Denitrification Activities And Survival Rate Of Litopenaeus Vannamei." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/92207853154471814930.

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碩士<br>國立高雄海洋科技大學<br>海洋生物技術研究所<br>100<br>Litopenaeus vannamei, Pacific white shrimp, is one of the most intensively cultivated shrimps in the world. It is the most important commercially penaeid shrimp in Taiwan. Nitrite is one of the most important factors in pond water affecting shrimp’s survival and health. This study aimed to find how heterotrophic denitrification bacteria decompose nitrite in water and enhanc white shrimps survival rate at wide ranges of salinities and temperatures. Our results demonstrated that A5 and T bacteria are able to reduce nitrite up to 95% at different salinities

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18

CHIU, SHAO-WEN, and 邱紹文. "Assessment of The Overall Survival Rate of Cancer Using A Revised Taylor Expansion Algorithm- A Taiwanese Population-Based Survey for Breast And Colon Cancers." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/3y7taq.

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博士<br>中臺科技大學<br>醫學影像暨放射科學系暨研究所<br>107<br>This paper explores the overall survival (OS) analysis using the Taylor expansion algorithm to give different interpretations of the survival curve under different stages of cancer with different treatments. Breast and colon cancers were selected examples for in-depth discussion. The proposed speculation was based on the theory of the hit and target model and make use of the Taylor expansion algorithm applied in Taiwanese population-based survey. The overall survival (OS) is the most commonly used assessment indicator for survival analysis, also calle

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