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Journal articles on the topic 'Rare neoplasias'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Ulrikh, E. A., E. L. Dikareva, A. D. Dzharbaeva, et al. "Trophoblastic neoplasia on the background of developing pregnancy: a rare gynecological tumor with a chance of favorable outcome for mother and fetus." Tumors of female reproductive system 18, no. 3 (2022): 112–17. http://dx.doi.org/10.17650/1994-4098-2022-18-3-112-117.

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Trophoblastic neoplasias are rare tumors, accounting for less than 1 % of malignant neoplasms of the female genital tract. Trophoblastic tumors associated with developing pregnancy are extremely rare. The article presents the successful experience of diagnostics and treatment of intraplacental chorioncarcinoma associated with progressing pregnancy.

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2

Roseira, Louise De Faro Teles, Fernando Correia Loiola, and Virgílio Ribeiro Guedes. "NEOPLASIAS PRIMÁRIAS DO BAÇO." Revista de Patologia do Tocantins 4, no. 2 (2017): 21. http://dx.doi.org/10.20873/uft.2446-6492.2017v4n2p21.

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As neoplasias primárias do baço constituem um grupo com baixa taxa de incidência na prática médica. Por compreender várias patologias raras com manifestações inespecíficas, o diagnóstico na grande maioria dos casos só é dado após realização de esplenectomia e análise anatomopatológica do material. Este trabalho tem como finalidade apresentar uma revisão de literatura acerca de algumas das principais neoplasias primárias do baço, benignas e malignas, discutindo os principais sintomas, diagnóstico e tratamento das mesmas.Palavras-chave: Neoplasias, Baço, Esplenectomia. ABSTRACT Prima

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3

Oliva, Fernando Cascelli, Gabriel José Dos Santos, Gustavo Hideki Hideki Orikasa, et al. "Tumor de Frantz: desafios diagnósticos e terapêuticos: relato de caso / Frantz’s tumor: diagnostic and therapeutic challenges: case report." Arquivos Médicos dos Hospitais e da Faculdade de Ciências Médicas da Santa Casa de São Paulo 64, no. 1 (2019): 65. http://dx.doi.org/10.26432/1809-3019.2019.64.1.065.

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Introdução: O tumor sólido pseudopapilar do pâncreas ou Tumor de Frantz, é uma neoplasia rara, que acomete preferencialmente mulheres jovens e apresenta bom prognóstico, com baixas taxas de mortalidade. Relato de Caso: O presente trabalho apresenta um caso de uma paciente da Santa Casa de São Paulo, com Tumor de Frantz, seu diagnóstico, tratamento e complicações pós pancreatectomia.Descritores: Pâncreas, Neoplasias pancreáticas, Carcinoma papilar, Pseudocisto pancreático, Fístula pancreáticaAbstractIntroduction: The solid pseudopapillary tumor, or Frantz’s tumor, is a rare neoplasm that occurs

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4

Diomidova, Valentina N., and Oksana A. Efimova. "Rare Histological Types of Malignant Gastric Neoplasms: Features of Histomorphological and Visual Structure." Acta medica Eurasica, no. 4 (December 27, 2024): 1–13. https://doi.org/10.47026/2413-4864-2024-4-1-13.

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Diagnosing rare histological types of malignant gastric neoplasms causes difficulty due to the nature of tumor growth, the lack of clear cellular differentiation and an extremely rare incidence. The aim of the study is to increase the accuracy of diagnosing rare types of malignant gastric neoplasms using modern methods of radiation diagnosis, depending on their histological characteristics. Materials and methods. The authors examined the data of patients with malignant gastric neoplasms of epithelial (N1, n = 385) and non-epithelial origin – gastrointestinal stromal tumor of the stomach (N2, n

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Zarochentseva, N. V., V. I. Krasnopolskiy, О. А. Misyukevich, I. V. Barinova, М. V. Mgeliashvili, and О. V. Rovinskaya. "Rare forms of vaginal diseases in women after panhysterectomy." Voprosy ginekologii, akušerstva i perinatologii 19, no. 5 (2020): 150–55. http://dx.doi.org/10.20953/1726-1678-2020-5-150-155.

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The article presents clinical observations of the development of precancerous conditions of the vaginal vault, and also squamous cell cancer in women after panhysterectomy. The examination included: comprehensive vaginoscopy, cytological examination of vaginal wall smears, human papillomavirus test, histological examination of bioplates. Conclusion. Panhysterectomy does not guarantee the absence of precancerous lesions of the vagina or vaginal cancer. Therefore, routine screening (cytology, testing for high-risk human papillomavirus, vaginoscopy) should be continued in women after panhysterect

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Beyshembaev, Almaz, Kirill Zhordania, and Tamara Zhekshenbek k. "Stromal cell ovarian tumors." Problems in oncology 67, no. 2 (2021): 210–16. http://dx.doi.org/10.37469/0507-3758-2021-67-2-210-216.

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This review represents the latest data about rare type of ovarian neoplasms - stromal cell tumors, which are 7-8% of all ovarian neoplasias. This group of diseases is characterized by an ambiguous prognosis and high recurrence rate. The paper presents a general characteristic of an emergency treatment, describes the most common and rare nosologicalal forms. The recent diagnostic and therapeutic approaches are characterised. The authors have shown in detail the problems in early diagnosis of primary stromal cell ovarian tumors and their relapses, the lack of a unified approach in therapeutic ta

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7

Beatrice, Laura, Felicitas Schär Boretti, Nadja S. Sieber-Ruckstuhl, et al. "Concurrent endocrine neoplasias in dogs and cats: a retrospective study (2004–2014)." Veterinary Record 182, no. 11 (2018): 323. http://dx.doi.org/10.1136/vr.104199.

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Multiple endocrine neoplasia (MEN) is a well-known syndrome in human medicine, whereas only a few cases of concurrent endocrine neoplasias have been reported in dogs and cats. The aim of this study was to evaluate the prevalence of concurrent endocrine neoplasias in dogs and cats at our clinic, identify possible breed and sex predispositions and investigate similarities with MEN syndromes in humans. Postmortem reports of 951 dogs and 1155 cats that died or were euthanased at the Clinic for Small Animal Internal Medicine, University of Zurich, between 2004 and 2014 were reviewed, and animals wi

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8

Kaur, Dr Gurpreet, Renu Madan, Raghav Sharma, and Arijit Sen. "A Rare Case of a Germ-Cell Tumour Associated with Acute Megakaryoblastic Leukaemia- An Autopsy Report with Review of Literature." Saudi Journal of Pathology and Microbiology 7, no. 7 (2022): 263–66. http://dx.doi.org/10.36348/sjpm.2022.v07i07.002.

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His association of mediastinal germ-cell tumours (MGCTs) with haematologic neoplasms is a rare though well known circumstance, and few cases are found in the literature. Most of these are non-seminomatous tumours in young males. The diagnosis of the haematological condition is usually either synchronic or metachronic with that of the germ-cell tumour. The prognosis is poor and basically determined by the haematologic neoplasia. Less than 20 cases of PMGCT with evolution into acute megakaryocytic leukemia have been reported in worldwide literature. Hematologic neoplasias associated with extrago

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9

Meshcheriakova, L. A., A. F. Maslennikov, N. A. Meshcheriakova, A. I. Pronin, M. A. Chekalova, and I. G. Komarov. "Positron emission tomography, combined with computed tomography, in resistent lesions of gestational trofoblastic tumors topical diagnostics." Russian Journal of Oncology 24, no. 3-6 (2020): 89–95. http://dx.doi.org/10.18821/1028-9984-2019-24-3-6-89-95.

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Introduction. Gestational trophoblastic neoplasias are rare tumors, which consist of about 1% of gynecological cancers. High rate of diagnostic and treatment mistakes leads to late diagnosis, metastatic appearance, resistance to chemotherapy, poor prognosis. Aim. To demonstrate possibilities of 18F-FDG PET/CT to find resistant lesions of gestational trophoblastic neoplasias. In the article, we analyze several medical reports to illustrate advantages of 18F-FDG PET/CT for evaluation of resistant gestational trophoblastic neoplasias.

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10

Kayukova, E. V. "Clinical case of malignant endometrioid-associated neoplasia of a postoperative scar." MD-Onco 4, no. 4 (2025): 107–10. https://doi.org/10.17650/2782-3202-2024-4-4-107-110.

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Malignant endometrioid-associated neoplasias are malignant tumors wich develop as a result of malignant transformation of endometrioid heterotopias outside the uterus. The mechanisms of their transformation are diverse, and oncological risks are known only for ovarian and breast cancer.The article presents a rare clinical case of malignant endometrioid-associated neoplasia of a postoperative scar in a 67-year-old woman. Differential criteria and prognostic factors of the disease course are considered. The literature data on this issue were analyzed. Literature search was carried out in PubMed,

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11

Yildiz, Baris D. "Giant Extra-Adrenal Retroperitoneal Myelolipoma With Incidental Gastric Mesenchymal Neoplasias." International Surgery 100, no. 6 (2015): 1018–20. http://dx.doi.org/10.9738/intsurg-d-14-00128.1.

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Extra-adrenal myelolipomas are rare, benign tumors composed of adipose tissue and hematopoietic cells. Almost all myelolipomas occur within the adrenal gland. Only 50 cases of myelolipomas were described in literature and none of these were associated with gastric mesenchymal neoplasia. A 72-year-old male patient presented to a family medicine outpatient clinic with dyspnea and urinary urgency. His abdominal sonography revealed a 9-cm intra-abdominal mass. An incidental finding was 2 separate masses 1 cm each on the serosal surface of the stomach. The pathology specimen of the retroperitoneal

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12

Güneş, Gizem, and Sadettin Er. "A rare cause of tumor ileus, neuroendocrin mixed non neuroendocrin neoplasm (MINEN): case report." Journal of Comprehensive Surgery 1, no. 4 (2023): 96–99. http://dx.doi.org/10.51271/jocs-0022.

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Mixed neuroendocrine-nonneuroendocrine neoplasias (MiNEN) are rare neoplasias with unknown pathophysiology. In order to make this diagnosis, neuroendocrine cell and adenocarcinoma components must be at least 30% each in the tumor. They are rarely seen in the colon. In this case, we aimed to present 2 cases who were operated due to tumor ileus and whose postoperative pathology results were compatible with MiNEN.

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13

Resende, Vivian, João Paulo Lemos da Silveira Santos, Rodrigo Vieira Gomes, Paula Vieira Teixeira Vidigal, and Moisés Salgado Pedrosa. "Papillary neoplasias of the biliary tract." Revista do Colégio Brasileiro de Cirurgiões 41, no. 6 (2014): 445–50. http://dx.doi.org/10.1590/0100-69912014006011.

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The authors conducted a revisional study of intraepithelial papillary lesions of the bile ducts, characterized by being a kind of rare, intraductal growing cholangiocarcinoma. Articles published in the last 10 years were reviewed. The authors considered that the adenoma-carcinoma development is an important feature to warrant prophylactic measures through excisions. The histological type and biomolecular behavior may have relevance in the postoperative course of such lesions, which have a better prognosis when compared with other histological types.

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14

Orlova, E. M., and M. A. Kareva. "Carney complex - multiple endocrine neoplasia syndrome." Problems of Endocrinology 58, no. 3 (2012): 22–30. http://dx.doi.org/10.14341/probl201258322-30.

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Carney complex is a rare hereditary syndrome characterized by an autosomal-dominant mode of inheritance and associated with multiple neoplasias affecting endocrine organs. The typical manifestations of this syndrome include pigmented micronodular adrenal dysplasia, lentiginosis, heart and skin myxomas, giant cell sertoliomas, and some other neoplasias. To date, a few hundred patients with this pathology have been described worldwide. A review of the available data about Carney complex is presented.

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15

Konishi, Kazuo, Lanlan Shen, Suna Wang, Stephen J. Meltzer, Noam Harpaz, and Jean–Pierre J. Issa. "Rare CpG Island Methylator Phenotype in Ulcerative Colitis–Associated Neoplasias." Gastroenterology 132, no. 4 (2007): 1254–60. http://dx.doi.org/10.1053/j.gastro.2007.01.035.

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16

Cabanas, P., T. García-Caballero, J. Barreiro, et al. "Papillary thyroid carcinoma after recombinant GH therapy for Turner syndrome." European Journal of Endocrinology 153, no. 4 (2005): 499–502. http://dx.doi.org/10.1530/eje.1.01988.

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Turner syndrome (TS) has been included for several years among the indications for GH treatment, generally with satisfactory outcomes. Nevertheless, the long-term effects of this treatment in non-GH deficient patients are not fully known. The incidence of thyroid carcinoma is rare in patients during childhood, it is unusual to find this neoplasia in children under sixteen years old. This article reports the cases of two Spanish patients with papillary thyroid carcinoma after GH treatment for TS. Recent studies have indicated a possible relationship between the GH–IGF axis and the pathogenesis

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Jacob, Marianne, Dustin Rowland, Oksana Lekarev, and Berrin Ergun-Longmire. "Multiple Endocrine Neoplasia in Childhood: An Update on Diagnosis, Screening, Management and Treatment." Endocrines 3, no. 1 (2022): 76–91. http://dx.doi.org/10.3390/endocrines3010007.

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Multiple endocrine neoplasia (MEN) is a group of heterogenous syndromes characterized by the occurrence of two or more endocrine gland tumors in a patient or related individuals in the same family. They are inherited in an autosomal dominant fashion and are highly penetrant. There are three types of MEN syndromes: MEN type 1 (MEN1), MEN type 2 (MEN2), and MEN type 4 (MEN4). MEN2 is further divided into MEN2A, MEN2B (formerly known MEN3), and familial medullary thyroid carcinoma (FMTC). Although MEN syndromes are rare, it is crucial to identify individuals at risk for potentially life-threateni

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18

Lyons, Keegan, and Samantha Butler. "Anal Intraepithelial Neoplasia from a Pathologists Point of View." Clinics in Colon and Rectal Surgery 31, no. 06 (2018): 328–35. http://dx.doi.org/10.1055/s-0038-1668102.

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AbstractAnal squamous cell carcinoma is a relatively rare diagnosis, but its incidence has continued to rise. Anal squamous cell carcinoma and its precursor lesion, anal intraepithelial neoplasia (AIN), are human papillomavirus (HPV)-associated squamous neoplasias. High-risk HPV subtypes cause cellular proliferation in the anal transformation zone mucosa leading to similar dysplastic changes as seen in the cervix. Unified cytologic and histologic classification systems have emerged for all HPV-associated squamous lesions of the lower anogenital tract due to recent advancements in the understan

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19

Lopes, Nilza, Eliana Caran, Maria Lucia Lee, Nasjla Saba Silva, André Caroli Rocha, and Carla Macedo. "Gorlin-Goltz Syndrome and Neoplasms: A Case Study." Journal of Clinical Pediatric Dentistry 35, no. 2 (2010): 203–6. http://dx.doi.org/10.17796/jcpd.35.2.x01248284w166485.

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Gorlin syndrome is a rare autosomal dominant disorder exhibiting high penetrance and variable expressivity. It is characterized by facial dysmorphism, skeletal anomalies, multiple basal cell carcinomas, odontogenic keratocysts (OKC), palmar and plantar pits, bifid ribs, vertebral anomalies and a variety of other malformations. Various neoplasms, such as medulloblastomas, meningiomas, ovarian and cardiac fibromas are also found in this syndrome. Objective: To describe a twelve-year-old patient with Gorlin-Goltz syndrome,with basal cell carcinomas and promyelocytic leukemia developed after recei

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20

Asprino, Paula Fontes, Rudinei Diogo Marques Linck, Jônatas Cesar, et al. "TSC2 rare germline variants in non-tuberous sclerosis patients with neuroendocrine neoplasias." Endocrine-Related Cancer 25, no. 2 (2018): L1—L5. http://dx.doi.org/10.1530/erc-17-0286.

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Reyna-Villasmil, Eduardo. "Manejo de neoplasias malignas gastrointestinales durante el embarazo." Revista de Obstetricia y Ginecología de Venezuela 81, no. 03 (2021): 273–86. http://dx.doi.org/10.51288/00810311.

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The incidence of cancer during pregnancy is rare and is often diagnosed in advanced stages. The frequency has increased due to delayed motherhood along with the increase in age-dependent malignancies among young adults. The most common cancers diagnosed during pregnancy are breast, cervical, hematological (lymphomas and acute leukemias) and melanoma. The least common are gastrointestinal. Diagnosis is challenging, the symptomatology is often attributed to the symptoms of pregnancy, which could delay diagnosis and allow the cancer to progress to advanced stages. Treating physicians have two pro

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Ono, Yusuke, Hidenori Karasaki, Koji Imai, et al. "Metachronous pancreatic cancer originating from disseminated founder pancreatic intraductal neoplasias." Journal of Clinical Oncology 33, no. 3_suppl (2015): 330. http://dx.doi.org/10.1200/jco.2015.33.3_suppl.330.

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330 Background: Clonal populations originated from benign-looking “founder cells” may spread widely within pancreas instead of being localized in situ before frank pancreatic ductal adenocarcinoma (PDA) can be detected. Metachronous PDA is not common event, and we here sought to define potent origin of multiple PDAs developed in a woman by using advanced genetics technologies. Methods: In addition to precise pathological assessment, genetic approaches such as deep sequencing of multiplex PCR amplicons of cancer-associated genes (Ion Torrent PGM platform) and digital PCR were employed. Results:

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Khakimov, G. A., G. G. Khakimova, F. B. Djumanova, G. P. Orifjonova, and Sh Sh Kadyrov. "Clinical case of a giant extragastrointestinal tumor of the retroperitoneum and review of the literature." Medical alphabet, no. 17 (September 6, 2024): 38–42. http://dx.doi.org/10.33667/2078-5631-2024-17-38-42.

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Extragastrointestinal stromal tumors (EGIST) are rare lesions in the mesenchymal neoplasm, accounting for less than 1% of the primary neoplasias of the digestive tract. In only 10% of the cases EGIST may affect any segment of the gastrointestinal tract and can occur in other locations (omentum, mesentery, or retroperitoneum, GIST arising from the pancreas). The incidence is approximately 14.5 patients per 1 million persons [1–3]. To date, more than 190 cases have been published. We reported a rare case of huge mesenteric extra-gastrointestinal stromal tumor presenting as a peritoneal mass in a

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Melo, Mayron Duarte, Aryanne Silva Barros Vieira, Daniela da Silva Santos, and Jéssica de Souza Silva. "Papiloma oncocítico: um relato de experiência." Revista Remecs - Revista Multidisciplinar de Estudos Científicos em Saúde 9, no. 15 (2024): 209–15. http://dx.doi.org/10.24281/rremecs2024.9.15.209215.

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O presente relato descreve o caso de um paciente masculino diagnosticado em 2021 com apresentação rara de tumor com acometimento de fossa nasal. O papiloma oncocítico também chamado de papiloma de células cilíndricas é considerado um tumor raro com origem na membrana schneideriana, mucosa que reveste o nariz e os seios paranasais. Não há fatores de risco determinados para a causada doença. Possui sintomas clássicos como obstrução nasal, anosmia, saída de secreção e roncos. A tomografia computadorizada e a ressonância magnética são exames fundamentais para o diagnóstico, tratamento e acompanham

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Cambruzzi, Eduardo, Enilde Eloena Guerra, Hamilton Cardoso Hilgert, et al. "Primitive Neuroectodermal Tumor of the Liver: A Case Report." Case Reports in Medicine 2011 (2011): 1–4. http://dx.doi.org/10.1155/2011/748194.

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Primary liver sarcomas represent a rare group of neoplasias, with angiosarcoma being the most common histological type. Primitive neuroectodermal tumor (PNET) represents a high malignant neoplasia that usually affects the central nervous system and soft tissues. An 18-year-old male patient was admitted with clinical complains of pain in the right upper abdominal quadrant. The clinical evaluation revealed a solid mass in the right hepatic lobe. On the gross examination of the resected liver specimen, the right lobe of the liver was replaced by a yellow-red solid mass measuring 21 cm in its larg

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Grădinaru, Stoicea, Mocanu, Antoniac, Gheorghiță, and Grigore. "Rare Breast Carcinoma with Paradoxical Plasma Cell Immunoprofile: A Case Report." Medicina 56, no. 2 (2020): 62. http://dx.doi.org/10.3390/medicina56020062.

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Plasma cell features are encountered in a variety of non-plasma cell neoplasias, especially carcinomas of a discohesive type, such as those occurring in the digestive tract and breast. Lobular carcinomas of the breast present themselves in a variety of architectural patterns and many cell morphologies, including plasmacytoid types. A matching plasma cell phenotype is sometimes an associated feature. We report a case of a moderate grade invasive lobular carcinoma with focal plasmacytoid morphology and aberrant expression of plasma cell markers in a patient previously diagnosed with multiple mye

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Patyutko, Yu I., D. V. Podluzhny, Olesya N. Soloveva, et al. "CLINICAL CASE: NEUROENDOCRINE TUMOR OF THE SMALL INTESTINE - METASTASES IN THE LIVER, PANCREAS AND KINDEY. THE RARITY OF OBSERVATION." Russian Journal of Oncology 23, no. 1 (2018): 20–23. http://dx.doi.org/10.18821/1028-9984-2018-23-1-20-23.

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Neuroendocrine neoplasms are produced by a unique group of epithelial neoplasias that exhibit common neuroendocrine characteristics and have specific terminology, classification, semiotics, and specific approaches to diagnosis and treatment. Neuroendocrine neoplasms (NEP) are most often found in the gastrointestinal tract (GIT), mainly in the small intestine. The most frequently detected metastases of GIT NEP are metastases in the liver (95%), distant metastases to other organs, such as the pancreas or kidney are extremely rare. Case report: a 45-year-old patient K., who was admitted to the de

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Branca, Giovanni, and Valeria Barresi. "Müllerianosis of the Urinary Bladder: A Rare Tumorlike Lesion." Archives of Pathology & Laboratory Medicine 138, no. 3 (2014): 432–36. http://dx.doi.org/10.5858/arpa.2012-0681-rs.

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Müllerianosis was first described as a rare entity consisting of an admixture of cervical, tubaric, or endometrial epithelium within the lamina propria and muscularis propria of the urinary bladder. This lesion occurs mainly in the dome or posterior wall of the urinary bladder in women of fertile age. Its clinical presentation is characterized by hematuria, pelvic pain, and dysuria, nonspecific symptoms that are related to the responsiveness of müllerian glands to hormonal stimuli. The major interest of müllerianosis resides in its similarity, from clinical, cytologic, and histologic viewpoint

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Basolo, Fulvio, Raffaele Pingitore, and Angelo Gadducci. "Osteosarcoma of the Myometrium Synchronous with Bilateral Papillary Cystadenocarcinoma of the Ovary and Papillary Adenocarcinoma of the Cervix." Tumori Journal 74, no. 2 (1988): 227–31. http://dx.doi.org/10.1177/030089168807400219.

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We report an extremely rare case of a 60-year-old woman with myometrial osteosarcoma associated with bilateral papillary cystadenocarcinoma of the ovary and papillary adenocarcinoma of the cervix. The uterine osteosarcoma is the seventh case reported in the world, while it is the second case of syncronous triple primary tumors of the upper female genital tract. Clinical and pathological features of previously reported cases of uterine osteosarcoma and triple primary neoplasias of the upper female genital tract are critically reviewed.

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Aguiar, Guilherme Brasileiro de, Karla Helena Picoli Natário, Heitor Castelo Branco Rodrigues Alves, Thays Filizzola Borges, and Marcus André Acioly. "Hemorragia cerebral espontânea como manifestação inicial de glioma multicêntrico / Spontaneous cerebral haemorrhage as an initial manifestation of multicentric glioma." Arquivos Médicos dos Hospitais e da Faculdade de Ciências Médicas da Santa Casa de São Paulo 64, no. 2 (2019): 169. http://dx.doi.org/10.26432/1809-3019.2019.64.2.169.

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Introdução / Objetivos: Os gliomas multicêntricos são neoplasias malignas raras e importantes no diagnóstico diferencial de lesões cerebrais múltiplas. São representados por lesões múltiplas, localizadas em lobos ou hemisférios cerebrais distintos, com ausência de contiguidade entre as lesões e de vias de disseminação anatômica ou formações satélites. Apresentam manifestação clínica heterogênea a depender da área cometida. A ressonância magnética é o recurso utilizado para investigação diagnóstica, onde pode-se avaliar a ausência de contiguidade entre as lesões. O objetivo do presente estudo é

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Boza Oreamuno DDS, MSc, Yadira V. "Basaloid Squamous Cell Carcinoma of the Palate: Case Report." Odovtos - International Journal of Dental Sciences 19, no. 3 (2017): 17. http://dx.doi.org/10.15517/ijds.v19i3.29667.

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Basaloid Squamous Cell Carcinoma (BSCC) is a rare and aggressive variant of squamous cell carcinoma (SCC), with a predilection for the upper aerodigestive tract, the palate being a very rare site of development. It is constituted by a basaloid and a squamous components in variable proportions, however, the histopathological characteristics of the BSCC overlap with other neoplasias. Diagnosis with various immunohistochemical markers such as p63, Ki67, p16, and AE1 / AE3 cytokeratins have become a necessity for the specialist. The objective of this study is to present a case of BSCC in soft pala

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Zambarda, Taís Teixeira, Mariana De Jesus De Souza, Jéssica Moreira Cannavon, Clarisse Felten, Saulo Petinatti Pavarini, and Álan Gomes Pöppl. "Mixossarcoma esplênico em cão." Acta Scientiae Veterinariae 45 (June 27, 2017): 4. http://dx.doi.org/10.22456/1679-9216.86239.

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Background: Myxosarcomas (MXS) are malignant mesenchymal neoplasms originated from mainly mucin producing fibroblasts than collagen. Despite malignant neoplasms, MXS is believed to have low metastase generation ability. Myxosarcomas reports in dogs are widespread, usually involving trunk and limbs subcutaneous tissue. The aim of this report is to describe clinical, pathological, and immunohistochemistry aspects of a rare case of splenic myxosarcoma in a dog.Case: A 10-year-old, intact male Basset Hound, weiging 25 kg, showing signals such apathy, dark soft-stooled stools, progressive thinning,

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Shah, Afsana, Santhosh Meedimale, Dinesh Kumar, Pooja Sharma, and Pragya Shukla. "Drug-induced acute febrile neutrophilic dermatosis (Sweet syndrome): A case report presented at Delhi State Cancer Institute." Journal of Cancer Research and Therapeutics 20, no. 5 (2023): 1605–7. http://dx.doi.org/10.4103/jcrt.jcrt_274_22.

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ABSTRACT Sweet syndrome is a rare, etiologically unknown dermatosis that can be idiopathic or associated with certain clinical conditions. Among these conditions are infections, autoimmune diseases, inflammatory bowel diseases, vaccinations, the use of medications, and neoplasias. Hematological neoplasias, particularly acute myeloid leukemia, are the most commonly described; however, the condition may also be related to solid tumors, being those of the genitourinary tract the most associated with the syndrome. Drug-induced Sweet syndrome has also been reported; however, it is rarely seen. We r

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Benjelloun, H., Z. Hanyn, N. Zaghba, K. Chaanoun, H. Harraz, and N. Yassine. "Pleomorphic Carcinoma of Pulmonary Location: Case Report and Review of the Literature." Scholars Journal of Medical Case Reports 12, no. 03 (2024): 303–6. http://dx.doi.org/10.36347/sjmcr.2024.v12i03.017.

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Pulmonary pleomorphic carcinoma is a rare primary lung tumor, part of the group of non-small cell cancers. We report the case of a 54-year-old patient, a chronic smoker who presented with hemoptysis evolving in a context of deterioration in general condition. Chest imaging revealeda left upper lobar tissue density mass with some hypodensity. The diagnosis of pleomorphic lung carcinoma was made based on histological data from bronchial biopsies, and classified as stage IVb according to the TNM classification (8th edition). Palliative chemotherapy was then offered to the patient. The evolution w

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Singh, Jyoti, Jai Lal Davessar, Sumit Prinja, and Nitin Arora. "Angiosarcoma of the nasal cavity and paranasal sinuses: a rare case report." International Journal of Otorhinolaryngology and Head and Neck Surgery 3, no. 3 (2017): 735. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20173058.

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<p class="abstract">Angiosarcomas are the malignant neoplasias of vascular phenotype whose constituent tumor cells have endothelial features. They account for less than 1% of all sinonasal tract malignancies. A case of 65 year old male with a 6 months history of spontaneous epistaxis and a nasal mass lesion presented to the OPD. On physical examination, a polypoidal purplish tumor of 6 × 5 cm was identified. A NCCT scan of nose and paranasal sinuses showed a nonenhanced tumor in the left nostril in maxillary, ethmoid, sphenoid and frontal sinus. An excisional biopsy revealed a poorly dif

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Correa, Fernanda de Lima, Luciana Wolfran, Aline de Marco Viott, Juliana das Chagas Goulart, Flávio Shigueru Jojima, and Paula Agostini. "Pulmonary metastasis of transmissible venereal tumour in a dog: a case report." Acta Veterinaria Brasilica 15, no. 3 (2021): 192–97. http://dx.doi.org/10.21708/avb.2021.15.3.9809.

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The transmissible venereal tumour (TVT) is one of the most frequent neoplasias in dogs. This tumour has specific characteristics, and it is exclusively of canines. Its transmission occurs through viable neoplastic cell transplantation when in contact with mucosa or unhealthy skin and rarely metastasise. This paper aims to report a rare presentation of pulmonary metastasis of widespread transmissible venereal tumours in a Blue Heeler dog. The patient was cachectic, dyspnoeic, and dehydrated and had multiple skin and pharynx nodulations. The cytology of all cutaneous nodulations showed round vac

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Tilici, Dana M., Alexandra Mirică, Ana M. Arnăutu, et al. "Sculpting Hope: Advanced MEN 2 – Associated Tumors. A Narrative Review Starting from a Case Report." Romanian Journal of Military Medicine 127, no. 6 (2024): 462–71. https://doi.org/10.55453/rjmm.2024.127.6.6.

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Multiple endocrine neoplasias (MEN) represent a rare and intricate group of disorders with diverse endocrine and extraendocrine manifestations. Among the five identified types of MEN syndromes, MEN 2 stands out due to its complexity, featuring medullary thyroid carcinoma (MTC), pheochromocytoma, and primary hyperparathyroidism (PHPT). MEN 2 is inherited in an autosomal dominant manner, with nearly a 100% lifetime risk of developing MTC, which can be fatal if not detected early. Comprehensive diagnostic protocols and timely interventions significantly mitigate morbidity. To guide surgical decis

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Drozdov, E. S., M. Yu Grishchenko, V. I. Kharitonkin, et al. "A rare clinical case of a patient with mixed neuroendocrine-non-neuroendocrine neoplasms of the ampulla of vater." Siberian journal of oncology 22, no. 2 (2023): 168–74. http://dx.doi.org/10.21294/1814-4861-2023-22-2-168-174.

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Background. Neuroendocrine tumors are rare neoplasias accounting for 1 % of all digestive malignancies. In 2010, mixed neuroendocrine-non-neuroendocrine neoplasms (MiNENs) were classified by the World Health Organization This type of tumor is extremely rare and most commonly occurs in the appendix, colon, and rectum. To date, only 30 clinical cases of MINEN of the major duodenal papilla (MDP) have been described in the available world literature, while we have not found a description of this pathology in the domestic literature.Description of the clinical case. We present a case of a 64-year-o

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Sandoval, Carmenza Liliana, Bernarda Jinneth Acosta, Oscar Contreras, and Jorge Vargas. "Multiple myeloma and light-chain amyloidosis: a rare presentation." Case reports 4, no. 2 (2018): 99–110. http://dx.doi.org/10.15446/cr.v4n2.69047.

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Introducción. La amiloidosis sistémica primaria hace parte del espectro de neoplasias de células plasmáticas, donde las cadenas livianas de inmunoglobulina se depositan en múltiples órganos. El compromiso miopático con falla respiratoria y mieloma múltiple asociado es poco frecuente. Caso clínico. Se presenta el caso de un paciente con amiloidosis sistémica de cadenas livianas (AL) quien ingresó por miopatía con falla respiratoria e íleo adinámico, por lo que se llevó a la unidad de cuidados intensivos. Por histología se confirmó infiltración en piel y tracto digestivo y concomitantemente se p

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Schettert, Isolmar Tadeu, Izilda Aparecida Cardinalli, Margareth Castro Ozello, José Vassallo, Irene Lorand-Metze, and Cármino Antonio de Souza. "Hemophagocytic syndrome: pitfalls in its diagnosis." Sao Paulo Medical Journal 115, no. 5 (1997): 1548–52. http://dx.doi.org/10.1590/s1516-31801997000500007.

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The hemophagocytic syndrome (HS) is characterized by a clinical picture of fever, hepatosplenomegaly, lymphadenopathy and peripheral pancytopenia. The morphologic hallmark of this syndrome is the phagocytosis of hematopoietic elements by morphologically normal macrophages. HS is considered rare and may be a primary disease or associated to viral, infection, neoplasias or autoimmune diseases. Treatment is controversial and its evolution is often fatal. Anatomo-pathological evaluation shows the phenomenon of hemophagocytosis in several organs, especially the hematopoietic tissues. We describe a

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Brás, G., C. Pinho-Vaz, and A. Campos. "Donor-Cell Origin High-Risk Myelodysplastic Syndrome Synchronous with an Intracranial Meningioma-Like Tumor, 8 Years after Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Lymphocytic Leukemia." Case Reports in Medicine 2017 (2017): 1–5. http://dx.doi.org/10.1155/2017/9674385.

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Secondary neoplasias are well known consequences of radiotherapy or chemotherapy for a primary cancer. In this report, we describe two rare secondary neoplasias occurring in the same patient: a meningioma-like intracranial tumor and high-risk myelodysplastic syndrome (MDS) of donor-cells origin, both diagnosed simultaneously, 8 years after an allogeneic hematopoietic stem cell transplantation (allo-HSCT) for chronic lymphocytic leukemia (CLL). Due to an engraftment failure during the first allo-HSCT of a matched related donor for CLL treatment, the salvage treatment was a second allo-HSCT. At

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Iyengar, Varun, Hetal Mistry, Catherine Hibbitt, and Alexei Shimanovsky. "Diagnosis and management of a metastatic mixed gestational trophoblastic neoplasia with synchronous primary lung cancer." BMJ Case Reports 14, no. 5 (2021): e240606. http://dx.doi.org/10.1136/bcr-2020-240606.

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Mixed gestational trophoblastic neoplasias (GTNs) are rare placental tumours that arise from abnormal fertilisation events. To date, only 34 patients with mixed GTNs have been reported in the literature. As such, the management of such cases remains challenging. This report presents a case of a mixed GTN that was further complicated by a synchronous primary lung adenocarcinoma. Our patient was initially treated with hysterectomy, with surveillance labwork showing persistence of her malignancy. She then began combination chemotherapy, at the end of which she appeared to be in remission clinical

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Matthews-Greer, Janice, Hugo Dominguez-Malagon, Guillermo A. Herrera, et al. "Human Papillomavirus Typing of Rare Cervical Carcinomas." Archives of Pathology & Laboratory Medicine 128, no. 5 (2004): 553–56. http://dx.doi.org/10.5858/2004-128-553-hptorc.

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Abstract Context.—Most cervical tumors are classified as squamous cell carcinoma or adenocarcinoma, both of which are associated with persistent human papillomavirus (HPV) infection. Although other (rare) types represent less than 5% of all cervical carcinomas, it is necessary that these more unusual tumors be studied in the current era of papillomavirus vaccine development, especially in regions with high incidence of cervical cancer. Objective.—To compare papillomavirus types found in histologically rare cervical carcinomas (n = 29) with those types found in common cervical carcinomas (n = 1

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Aghdassi, Ali, Agnes Christoph, Frank Dombrowski, et al. "Gastrointestinal Stromal Tumors: Clinical Symptoms, Location, Metastasis Formation, and Associated Malignancies in a Single Center Retrospective Study." Digestive Diseases 36, no. 5 (2018): 337–45. http://dx.doi.org/10.1159/000489556.

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Background and Aims: Gastrointestinal stromal tumors (GISTs) are rare malignancies but the most common mesenchymal tumors of the digestive tract. Recent advances in diagnostic imaging and an increasing incidence will confront us more frequently with stromal tumors. This single center study aimed to characterize GIST patients in terms of tumor location, clinical presentation, metastasis formation, as well as associated secondary malignancies. Methods: In a retrospective study, 104 patients with a histologically confirmed diagnosis of GIST, collected between 1993 and 2011, were characterized for

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Souza, Paulyanara Monique Alves de, Jefferson Ricardo Rodrigues Morais, Karla Vanessa Rodrigues Morais, Josué Da Silva Brito, and Talitha Araújo Faria. "Adenoma hipofisário secretor de TSH: uma revisão sistemática / TSH-secreting pituitary adenoma: a systematic review." Arquivos Médicos dos Hospitais e da Faculdade de Ciências Médicas da Santa Casa de São Paulo 65, no. 1 (2020): 1. http://dx.doi.org/10.26432/1809-3019.2020.65.035.

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Introdução: Os adenomas hipofisários são tumores caracterizados pela proliferação de células adeno-hipofisárias produtoras de hormônios tróficos. Dentre eles, os adenomas hipofisários produtores de TSH (TSHomas), neoplasias benignas pouco frequentes, que correspondem a menos do que 3% dos adenomas hipofisários. Método: Pesquisamos os termos TSHomas, tireotropinomas e adenomas pituitários secretores de TSH nas bases Pubmed, Lilacs e Scielo. Incluímos artigos publicados entre 2010 e 2020, sendo excluídos relatos de casos, artigos indisponíveis e que não tratavam sobre o tema. Resultados e discus

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Wang, Huan-You, and Youli Zu. "Diagnostic Algorithm of Common Mature B-Cell Lymphomas by Immunohistochemistry." Archives of Pathology & Laboratory Medicine 141, no. 9 (2017): 1236–46. http://dx.doi.org/10.5858/arpa.2016-0521-ra.

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Context.— Different types of mature B-cell lymphomas, including plasma cell neoplasms, exhibit distinct immunohistochemical profiles, which enable them to be correctly diagnosed. However, except for rare examples of lymphoma-specific immunohistochemistry, such as cyclin D1 in mantle cell lymphoma and annexin A1 in hairy cell leukemia, immunohistochemical profiles of mature B-cell lymphomas overlap and lack specificity. Objectives.— To systemically review immunohistochemical features associated with commonly encountered mature B-cell lymphomas based on the presence or absence of CD5 and CD10; t

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Natoli, Guido, Jasna Metovic, Stefano Taraglio, Stefania Miraglia, Francesca Misischi, and Luisa Delsedime. "A rare case of metastatic testicular adult granulosa cell tumor." Journal of Clinical Oncology 38, no. 15_suppl (2020): e15506-e15506. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e15506.

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e15506 Background: Adult granulosa cell tumour (AGCT) is a rare disease that develops in the testis, composed of sex cord cells, accounting for less than 0.5% of all sex cord-stromal neoplasias (WHO 2016). To our knowledge, 48 cases of AGCT of the testis have been published up to date reporting follow-up (Table 1). Infrequently, these tumors can metastasize, usually to retroperitoneal lymph nodes, but also liver, lungs and bones. Methods: In 2015 a 60-year-old Caucasian male with unilateral, painless slowly growing mass underwent to orchioectomy. A diagnosis of malignant ADTC was rendered. Aft

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Quiroga-Padilla, Pedro José, Deyanira González-Devia, Rafael Andrade, Paola Escalante, and Enrique Jiménez-Hakim. "Sellar Gangliocytoma: Case Report and Review of an Extremely Rare Tumour." Case Reports in Neurology 13, no. 2 (2021): 475–82. http://dx.doi.org/10.1159/000517368.

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Sellar gangliocytomas (SGs) are rare, well-differentiated, low-grade neoplasias that commonly present along with a pituitary adenoma (PA). We describe a case of a 52-year-old woman with a 2-year history of headache, body weight increase, and recent onset of arterial hypertension and type 2 diabetes mellitus. Work-up tests revealed a normal hypophyseal profile, except for mild ACTH elevation, and a sellar mass on magnetic resonance imaging (MRI). A diagnosis of an enlarging pituitary macroadenoma was established, and to prevent symptom progression, the tumour was resected. Pathology showed 2 ce

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Torres, Eliângela, Paula Cava Rodrigues, Maria Carolina Ferraz de Carvalho, et al. "Bilateral renal sarcoma in a bitch." Clínica Veterinária XXI, no. 124 (2016): 106–12. http://dx.doi.org/10.46958/rcv.2016.xxi.n.124.p.106-112.

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Renal neoplasias are rare in dogs. When these occur, they usually affect middle-aged dogs from medium to large breeds, and most of them with malignant behavior. Only 7-11% of these tumors are of mesenchymal origin. Renal mesenchymal metastases appear most frequently in the lungs and abdominal organs. Clinical signs are non-specific, such as weight loss, inappetence and hematuria. This article describes a case of renal stromal sarcoma in a 7-year-old Rottweiler bitch. The main symptoms were fatigue and prostration. Exams showed anemia and neoplastic lesions in both kidneys, liver and jejunum. U

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Sathiyaseelan, Naveen, Mahaveer Meena, and Purushottam Jhanwar. "Unraveling the Mystery of Parosteal Lipoma of the Distal Femur: A Rare Case Report." Journal of Orthopaedic Case Reports 13, no. 7 (2023): 82–85. http://dx.doi.org/10.13107/jocr.2023.v13.i07.3762.

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Introduction: Among all the primary bone tumors and all the type of lipomas, parosteal lipomas stand for <0.1% and 0.3%, respectively, which mostly consists of fully developed adipose tissue with or without a bony component. Patients with this tumor usually have bony lesions (59.2%), necessitating a differential diagnosis of malignant tumors. Case Report: Here, we analyze a case report of a 9-year-old boy, who developed a parosteal lipoma in the distal femur. A massive, well-defined, lobulated, mostly fat-intensity lesion of 10 cm by 6 cm by 8 cm was seen on an magnetic resonance imaging sc

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