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Dissertations / Theses on the topic 'Rat carotid body cells'

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1

O'Donnell, Jean. "Mechanism of excitation of carotid body chemoreceptor cells." Thesis, University of Oxford, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.236119.

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2

Burlon, Drew C. "THE PRESYNAPTIC REGULATION OF ISOLATED NEONATAL RAT CAROTID BODY TYPE I CELLS BY HISTAMINE." Wright State University / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=wright1252943387.

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3

Ricker, Ellen M. "The inhibitory effects of opioids on voltage-gated calcium influx in neonatal rat carotid body type I cells." Wright State University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=wright1424262410.

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4

Dunn, Eric J. "Effect of Somatostatin on Voltage-Gated CalciumInflux in Isolated Neonatal Rat Carotid Body Type I Cells." Wright State University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=wright1432132454.

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5

Jackson, Adele. "Oxygen sensing, plasticity and catecholaminergic functions in cultured chromaffin cells of rat carotid body and adrenal medulla : modulation by chronic hypoxia and acetylcholine receptors /." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape16/PQDD_0018/NQ30096.pdf.

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6

Richmond, Patrick Henry. "The regulation of intracellular pH (pHi) and its role in chemoreception in the carotid body type-1 cell of the neonatal rat." Thesis, University of Oxford, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.359506.

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7

Rakoczy, Ryan J. "Measuring the Effects of High-Fat Diet on Breathing and Oxygen-Sensitivity of the Carotid Body Type I Cell." Wright State University / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=wright1505728876488752.

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8

Arnold, Alexandre José Tavolari. "O papel do corpúsculo carotídeo na insuficiência cardíaca induzida pela doxorrubicina." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/5/5160/tde-05062018-121228/.

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A insuficiência cardíaca (IC) é o estágio final de diversas patologias cardíacas e apresenta alta morbimortalidade. Dentre as causas, estão os efeitos cardiotóxicos em pacientes tratados com doxorrubicina (Dox). A fisiopatologia da IC apresenta aumento da atividade barorreflexa e marcada hiperatividade simpática (HS), estado compensatório à redução do débito cardíaco. Porém, a HS prolongada culmina em alterações deletérias para o sistema cardiovascular (SC) com piora do quadro de sintomas. Atualmente muito se discute sobre o papel dos corpúsculos carotídeos (CC) na fisiopatologia da IC devido
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9

Shaw, Karen. "Stimulus-secretion coupling in the rat carotid body." Thesis, University of Leicester, 1989. http://hdl.handle.net/2381/35148.

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The effects of a variety of agents known to stimulate chemoafferent activity were employed to define in greater detail the stimulus-secretion coupling mechanism in the rat carotid body superfused in vitro. Hypoxia, carbachol and sodium cyanide were independently able to elicit amine release. Hypoxia-evoked release was calcium dependent and was reduced by nitrendipine suggesting the involvement of voltage-dependent calcium channels in the secretory response. The effect of carbachol on catecholamine release was abolished by atropine indicating the presence of muscarinic cholinergic receptors on
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10

Paulet, Julia. "MATURATION OF THE CAROTID BODY OXYGEN-SENSOR DURING RAT DEVELOPMENT." Wright State University / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=wright1337703804.

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11

Thompson, Carrie Marie. "PRESYNAPTIC REGULATION OF CAROTID BODY TYPE I CELLS BY HISTAMINERGIC AND MUSCARINIC RECEPTORS." Wright State University / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=wright1283278640.

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12

Zhong, Huijun. "Electrophysiology and transmitter sensitivities of isolated rat petrosal neurons : synapse formation and hypoxic signaling in co-culture with carotid body chemoreceptors /." *McMaster only, 1997.

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13

Campanucci, Veronica A. Nurse Colin A. "Electrophysiological properties, PO₂- and ATP-sensitivity of paraganglion neurons of the rat glossopharyngeal nerve /." *McMaster only, 2004.

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14

Huskens, Nicky. "Novel interactions of volatile anaesthetics on 0₂ sensing and TASK channels in carotid body type-1 cells." Thesis, University of Oxford, 2015. https://ora.ox.ac.uk/objects/uuid:3ea6b847-f61a-4174-a12e-fc3e5e2b8da7.

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Hypoxia elicits a carotid body-mediated increase in minute ventilation, called the chemoreflex. Volatile anaesthetics depress this chemoreflex, even at sub-anaesthetic doses. The broad aim of this thesis is to explore how these anaesthetics act on carotid body mechanisms to depress the chemoreflex. The agents studied in this thesis are halothane (a potent depressant of this reflex), isoflurane (a less potent depressant) and sevoflurane (a weak depressant). Intracellular Ca2+ measurements, mitochondrial NADH and potential measurements, and single channel electrophysiology studies were performed
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15

Jurcsisn, Jennifer G. "THE CAMKKβ INHIBITOR STO-609 CAUSES ARTEFACTS IN Ca2+ IMAGING AND SELECTIVELY INHIBITS BKCa IN MOUSE CAROTID BODY TYPE I CELLS". Wright State University / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=wright1400059795.

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16

Hockman, Dorit. "The development and evolution of vertebrate oxygen-sensing cells." Thesis, University of Cambridge, 2014. https://www.repository.cam.ac.uk/handle/1810/276679.

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Oxygen-sensing cells release neurotransmitters, including serotonin, in response to hypoxia in the blood or surrounding air/water. This stimulates the glossopharyngeal and/or vagal nerves, triggering increased ventilation via the respiratory reflex. In the adult, they are located in the carotid body (glomus cells) and lung epithelia (pulmonary neuroendocrine cells) of amniotes, and in the epithelia of the gills and orobranchial cavity (‘neuroepithelial cells’) of anamniotes. Despite their physiological importance, little is known about the molecular mechanisms of their development, while the e
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17

Zhang, Jin 1960. "The influence of copper deficiency on the binding and uptake of high-density lipoprotein by rat hepatic parenchymal cells." Thesis, The University of Arizona, 1988. http://hdl.handle.net/10150/276935.

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This study was designed to examine the influence of Cu deficiency on the binding, uptake, and degradation of apolipoprotein E-free high density lipoproteins (apo E-free HDL) in cultured rat hepatic parenchymal cells. The binding of apo E-free HDL during time course studies was slightly but significantly increased in cells derived from Cu-deficient rats. In saturation studies, the amount of surface-bound apo E-free HDL appeared to be saturable, although no difference was observed between Cu-deficient and adequate animals. The amount of total and specific cell-associated uptake of apo E-free HDL
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18

Nunes, Ana Rita Silva Martins. "O2/CO2-sensitive cyclic AMP-signalling pathway in peripheral chemoreceptors." Doctoral thesis, Faculdade de Ciências Médicas. UNL, 2013. http://hdl.handle.net/10362/9153.

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RESUMO: O corpo carotídeo (CB) é um pequeno órgão sensível a variações na PaO2, PaCO2 e pH. As células tipo I (células glómicas) do corpo carotídeo, as unidades sensoriais deste órgão, libertam neurotransmissores em resposta às variações dos gases arteriais. Estes neurotransmissores atuam quer em recetores pré-sinápticos, localizados nas células tipo I, quer em recetores póssinápticos, localizados nas terminações do nervo do seio carotídeo, ou em ambos. A activação dos recetores pré-sinápticos modula a atividade do corpo carotídeo, enquanto que, a activação dos recetores pós-sinápticos, de
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19

Falvey, Aidan. "Étude du rôle du nerf sinuso-carotidien dans l’inflammation : l'électrostimulation du nerf sinuso-carotidien chez la souris atténue l'inflammation en agissant sur l’axe hypotalamo-hypophyso-surrénalien et les cellules myéloïdes." Electronic Thesis or Diss., Université Côte d'Azur (ComUE), 2019. http://theses.univ-cotedazur.fr/2019AZUR4019.

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Les corps carotidiens sont des structures bilatérales situées au niveau de la bifurcation de l'artère carotide. Ils sont capables de détecter divers stimuli physiologiques tels que la concentration de gaz dans le sang et la pression sanguine. Suite à la variation de ces paramètres au-delà d’une valeur consigne, le corps carotidien, via un nerf afférent appelé nerf sinuso-carotidien (NSC), déclenche une réponse riposte par des voies nerveuses ou hormonales efférentes. De récentes études ont suggéré l’existence d’une relation entre le système immunitaire et le corps carotidien. Il a en particuli
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20

Zhou, Ting. "Transcriptome and Functional Analysis of Carotid Body Glomus Cells." Diss., 2016. http://hdl.handle.net/10161/12159.

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<p>The carotid body (CB) is a major arterial chemoreceptor containing glomus cells that are activated by changes in arterial blood contents including oxygen. Despite significant advancement in the characterization of their physiological properties, our understanding on the underlying molecular machinery and signaling pathway in CB glomus cells is still limited. </p><p>To overcome these limitations, in chapter 1, I demonstrated the first transcriptome profile of CB glomus cells using single cell sequencing technology, which allowed us to uncover a set of abundantly expressed genes, including no
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21

Chen, Wei-Shen, and 陳威伸. "Expression of Nestin in The Developing Vascular Smooth Muscle Cells of Rat Common Carotid Artery." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/35114294099856709971.

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22

Wang, Chia-Jung, and 王家蓉. "Inhibitory Effect of Indocyanine Green Mediated Photodynamic Therapy on Restenosis of Rat Carotid Arteries and Smooth Muscle Cells." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/ypf7ur.

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碩士<br>中原大學<br>生物醫學工程研究所<br>106<br>Photodynamic therapy (PDT) has been widely investigated in recent years in the treatment of cancer and non-cancer diseases. The basis of PDT is the accumulation of photosensitizers in the lesion site and activated by light of suitable wavelength which produced cytotoxic reactive oxygen species to achieve target toxic cytotoxicity. In this study, we first demonstrated that PDT combined with Indocyanine Green (ICG) using 780 nm light emitting diode irradiations could effectively inhibit carotid endothelial hyperplasia. Next, we studied the PDT effect on rat aort
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23

Hsieh, Pei-Lin, and 謝佩霖. "The inhibitory effects and action mechanism of compound 5185 on proliferation of vascular smooth muscle cells and neointima formation in rat carotid arteries." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/3hsb58.

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碩士<br>國立臺灣大學<br>藥理學研究所<br>98<br>Abnormal proliferation and migration of vascular smooth muscle cells (VSMCs) play an important role in the development of restenosis after percutaneous transluminal angioplasty (PTCA). PDGF has been recognized as one of the most important growth factors involved in this process. Compound 5185 [1-benzyl-2-(5-methyl-2-furyl) benzimidazole] is a benzimidazole derivative with anti-thrombotic activities. In this study, we investigated the effects of 5185 on VSMC proliferation, migration in vitro and neointima formation in rat balloon injury model in vivo. Our results
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24

KUO, HSIAO-JU, and 郭筱茹. "Proteomic investigation of the influences of ethanol extract of Cordyceps militaris fruit body cultivated on silkworm pupa on the protein expression in rat basophilic leukemia cells." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/q865h6.

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碩士<br>南臺科技大學<br>生物科技系<br>106<br>About 20% of the global population is affected by allergy, type 1 hypersensitivity, including atopic dermatitis, allergic rhinitis, allergic asthma, anaphylaxis, and food allergy. Cordyceps militaris is a popular traditional Chinese medicinal fungus. Cordyceps militaris has numerous therapeutic values, such as anti-tumor, anti-oxidation and immunomodulatory effects. The proteomics method to search for the ethanol extract of Cordyceps militaris fruit body (CM_EE)-affected genes that might clarify the molecular mechanism underlying IgE-mediated allergic response.
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