Relevant bibliographies by topics / Rational drug use

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Rational drug use'

Author: Grafiati
Published: 4 June 2021
Last updated: 25 July 2025

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Journal articles on the topic "Rational drug use"

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Miller, Geoffrey F. "Optimal drug use and rational drug policy." Behavioral and Brain Sciences 34, no. 6 (2011): 318–19. http://dx.doi.org/10.1017/s0140525x11000756.

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AbstractThe Müller & Schumann (M&S) view of drug use is courageous and compelling, with radical implications for drug policy and research. It implies that most nations prohibit most drugs that could promote happiness, social capital, and economic growth; that most individuals underuse rather than overuse drugs; and that behavioral scientists could use drugs more effectively in generating hypotheses and collaborating empathically.
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Mohammed, Solomon Ahmed, and Abebe Getie Faris. "The Pattern of Medicine Use in Ethiopia Using the WHO Core Drug Use Indicators." BioMed Research International 2021 (December 24, 2021): 1–11. http://dx.doi.org/10.1155/2021/7041926.

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Introduction. Rational medicine use is an appropriate prescribing, dispensing, and patient use of medicines for the diagnosis, prevention, and treatment of diseases. It is affected by several factors. Irrational use of medicine is a widespread problem at all levels of care. This review is aimed at assessing the medicine use pattern in health facilities of Ethiopia using the medicine use pattern developed by WHO/INRUD. Methods. Relevant literature was searched from Google Scholar, PubMed, Hinari, Web of Science, and Scopus using inclusion and exclusion criteria. A systematic review was used to
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ÇINAR, Fadime. "Rational Drug Use: Dentists Case." Social Sciences Studies Journal 6, no. 64 (2020): 2732–39. http://dx.doi.org/10.26449/sssj.2470.

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Sahingoz, Mehtap, and Elcin Balci. "Rational Drug Use of Nurses." TAF Preventive Medicine Bulletin 12, no. 1 (2013): 57. http://dx.doi.org/10.5455/pmb.1-1334045455.

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Gulhan, Rezzan. "Rational Drug Use in Elderly." Medical Journal of Okmeydani Training and Research Hospital 29, Supplement 2 (2014): 99–105. http://dx.doi.org/10.5222/otd.supp2.2013.099.

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AL Qamariat, Zahra Hassan. "Rational and Irrational Drug Use: Factors, Impacts and Strategies to Combat Irrational Drug Use: A Narrative Review." International Journal of Pharmaceutical Sciences and Clinical Pharmacy 2, no. 1 (2021): 6–17. http://dx.doi.org/10.47890/ijpscp/zahrahassanalqamariat/2021/24148307.

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Misuse of drugs is a serious health problem all around the world. Rational drug use can be characterized as follows: patients receive drugs that meet their clinical needs, at doses that meet their requirements, promptly and at the lowest cost to themselves and their region. Drug abuse, polypharmacy, and misuse are the most prominent drug use problems today. Misuse of drugs can occur for a variety of reasons at different levels, including recommended mistakes and over-the- counter medications. Inappropriate use of income can lead to real negative benefits and financial results. There are many i
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KARAGEÇİLİ, Hasan, and Emrah YERLİKAYA. "THE EVALUATION OF HEALTH SCHOOL STUDENTS RATIONAL DRUG USE KNOWLEDGE AND HABITS." Euroasia Journal of Mathematics, Engineering, Natural & Medical Sciences 9, no. 21 (2022): 56–66. http://dx.doi.org/10.38065/euroasiaorg.959.

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Unnecessary and improper medication use are problems that affect public health negatively. In our country, a significant portion of health expenditures is spent on medications. This study was aimed to evaluate the rational drug use knowledge and behaviors of students at Siirt University Health School. The study was carried out face to face with the participation of 568 students. The survey was carried out with the method of application under observation. The research population in which the questionnaire could be applied consisted of 980 students. Participation in the survey required volunteer
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สุวรรณกูฏ, พัชรินทร์. "การอบรม Effective drug management and rational drug use". Thai Journal of Pharmaceutical Sciences 19, № 4 (1995): 185–88. http://dx.doi.org/10.56808/3027-7922.1214.

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Nithya, R., Solanky K. Neesha, UDHAYAKUMAR Narmadha, R. R. Redlin, A. Ramya, and B. Manisha. "Exploring Drug Prescription Patterns in the Neurology Department of a Tertiary Care Hospital: A Comprehensive Analysis." Journal of Drug Delivery and Therapeutics 13, no. 7 (2023): 38–45. http://dx.doi.org/10.22270/jddt.v13i7.6139.

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Objective: Neurological disorders are a major cause of morbidity, mortality and disability. These adversely affect the quality of life among all age group patients. Majority of neurological disorders include Epilepsy, Headache, Cerebrovascular disorders with hemiparesis, Neuropathic pain, Extrapyramidal syndrome, Cervical myelopathy and Parkinson’s disease. This study was done with aim to evaluate the prescription pattern of various drugs in different types of neurological disorders and to use the WHO / INRUD prescribing indicators to assess the rational drug prescribing.
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Remmel, Marko, Franz Hartmann, Lars C. Harland, Heribert Schunkert, and Peter W. Radke. "Rational Use of Drug-Eluting Stents." Critical Pathways in Cardiology: A Journal of Evidence-Based Medicine 6, no. 2 (2007): 85–89. http://dx.doi.org/10.1097/hpc.0b013e318053d16f.

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Dissertations / Theses on the topic "Rational drug use"

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Giron, Maria Stella T. "The rational use of drugs in a population of very old persons /." Stockholm : [Karolinska institutets bibl.], 2002. http://diss.kib.ki.se/2002/91-7349-155-1.

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Cossins, Benjamin Philip. "The Use of Fast Free Energy Methods in Rational Drug Design." Thesis, University of Southampton, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.485031.

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The computationally demanding nature and lack of generality of free energy methods are the main barriers to their common place use in rational drug design. This study investigates the possibility of producing protocols to accurately calculate the binding free energy of protein-ligand complexes more efficiently than presently established methods, using large scale distributed computing. There has been an explosion of useful nonequilibrium work methods recently, mainly due to the discovery of the Jarzynski equilibrium [Jarzynski(1997b)]. After an indepth investigation of these methods a subset,
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Oguntunde, Olugbenga Olalere. "Drug prescribing practices among primary healthcare providers in a local government area of Northwestern Nigeria." University of the Western Cape, 2011. http://hdl.handle.net/11394/5378.

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Master of Public Health - MPH<br>Background: Drugs are essential components of the health system and their rational use is vital to delivering quality and efficient healthcare services. However, inappropriate prescribing is a common rational drug use problem globally, particularly in developing countries including Nigeria. Despite measures to address this problem, inappropriate drug use continues to be a major public health problem in Nigeria. Aim: This study assessed rational drug use (RDU), with a focus on rational prescribing and factors affecting it, among primary healthcare providers wor
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Joshua, Isaac B. "The impact of an intervention program for the treatment of malaria in children in Papua New Guinea." Thesis, Curtin University, 2003. http://hdl.handle.net/20.500.11937/2339.

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Malaria is more prevalent today and the death toll is on the increase annually. It is one of the leading causes of morbidity and mortality worldwide and most of these deaths are in the poorest regions of the world. About 500 million cases are reported annually with more than 2 million deaths, and most are children. It is the major killer in the tropics and a major public health problem in developing countries and Papua New Guinea (PNG) is no exception. Resistant strains have been reported. This may be enhanced by inappropriate human behaviour in the use of anti-malarial drugs. Human factors in
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Alali, Khaled Y. A. A. "Development of National Drug Policy in the State of Kuwait." Thesis, University of Bradford, 2016. http://hdl.handle.net/10454/16793.

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This Thesis examines the benefits and usefulness of a National Drug Policy (NDP) for the developing of the Health Care System in Kuwait. The NDP is one of the most important structures of the Health System which can lead to improved health services by establishing guidelines, proposals and directives to organize, structure and regulate health legislation; it is of help to ensure the availability of quality, safety and efficacy in using medicines and it can reduce the irrational use of medicines. The NDP is a frame work between the government, schools and universities, media, health professiona
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Orrell, Catherine Jane. "The development, initial implementation and support of a primary health care training programme in rational drug use." Master's thesis, University of Cape Town, 1998. http://hdl.handle.net/11427/26583.

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The Rational Drug Use Training Project is a district-oriented programme designed to improve rational drug use among primary health care prescribers in the South African public sector. This thesis describes the development of the project and details the initial implementation study in 3 facilities in Region B of KwaZulu-Natal. This was a small before-after study, with no control. There were three components: 1. A series of easily collectable drug use indicators, adapted from those developed by WHO/INRUD. These allow primary health care staff to monitor their prescribing patterns in a district o
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Joshua, Isaac B. "The impact of an intervention program for the treatment of malaria in children in Papua New Guinea." Curtin University of Technology, School of Pharmacy, 2003. http://espace.library.curtin.edu.au:80/R/?func=dbin-jump-full&object_id=13852.

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Malaria is more prevalent today and the death toll is on the increase annually. It is one of the leading causes of morbidity and mortality worldwide and most of these deaths are in the poorest regions of the world. About 500 million cases are reported annually with more than 2 million deaths, and most are children. It is the major killer in the tropics and a major public health problem in developing countries and Papua New Guinea (PNG) is no exception. Resistant strains have been reported. This may be enhanced by inappropriate human behaviour in the use of anti-malarial drugs. Human factors in
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Monanabela, Khathatso. "Rational drug therapy monitoring in type 2 diabetes mellitus : using glycated haemoglobin as a guide for change in therapy." University of the Western Cape, 2015. http://hdl.handle.net/11394/5305.

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>Magister Scientiae - MSc<br>Type 2 diabetes mellitus is a progressive disease characterised by defects in insulin secretion, insulin action or both. Proper management of diabetes with appropriate drug and lifestyle interventions, guided by proper glycaemic monitoring has shown improved glycaemic control and a substantial decrease in morbidity associated with complications and mortality. Evidence-based guidelines for the appropriate management of diabetes, suggests the use of glycated haemoglobin (HbA1c) and fasting plasma glucose (FPG) as monitoring indicators and have set targets levels that
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Olivera, Carolina Maria Xaubet. "Modelo de intervenções educativas para o uso racional de medicamentos." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/60/60137/tde-28112013-152058/.

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O farmacêutico, uma vez inserido na equipe multidisciplinar, tem um papel importante a desempenhar na educação em saúde com o objetivo de melhorar o conhecimento sobre as condições crônicas, refletindo positivamente na adesão ao tratamento e em conseqüência nos resultados clínicos e na qualidade de vida dos indivíduos. O objetivo deste estudo foi elaborar, implementar e avaliar o modelo de intervenções educativas para o uso racional de medicamentos. O estudo clínico longitudinal, prospectivo, randomizado foi conduzido por uma equipe multidisciplinar com 119 pacientes asmáticos (60/grupo contro
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Tanner, Delia Caroline. "Over-expression, purification and biochemical characterization of DOXP reductoisomerase and the rational design of novel anti-malarial drugs." Thesis, Rhodes University, 2004. http://hdl.handle.net/10962/d1003990.

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Malaria poses the greatest threat of all parasites to human life. Current vaccines and efficacious drugs are available however their use is limited due to toxicity, emergence of drug resistance, and cost. The discovery of an alternative pathway of isoprenoid biosynthesis, the non-mevalonate pathway, within the malarial parasite has resulted in development of novel anti-malarial drugs. 1-Deoxy-D-xylulose-5-phosphate (DOXP) reductoisomerase, the second enzyme in this pathway, is responsible for the synthesis of 2-C-methyl-D-erythritol 4-phosphate (MEP) in an intramolecular rearrangement step fol
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Books on the topic "Rational drug use"

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Massow, Fr Von. Guidelines to rational drug use. Macmillan, 1997.

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Workshop, on Essential Drugs Policy and Rational Drug Use (1987 Manila Philippines). Guide to rational drug use: Proceedings of a Workshop on Essential Drugs Policy and Rational Drug Use : November 7-10, 1987. Health Action Information Network, 1988.

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Voluntary Health Association of India., ed. Medicines, medical care, and drug policy: Rational Use of Drugs. Voluntary Health Association of India, 2000.

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Jayasuriya, D. C. Rational use of drugs and the Third World. Institute of Comparative Health, Policy, and Law, 1988.

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(India), National Rural Health Mission. Promoting rational drug use: Need for an NRHM Sub-mission. National Rural Health Mission, Ministry of Health & Family Welfare, 2009.

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Phadke, Anant. Drug supply and use: Towards a rational policy in India. Sage Publications, 1998.

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National Rural Health Mission (India). Promoting rational drug use: Need for an NRHM Sub-mission. National Rural Health Mission, Ministry of Health & Family Welfare, 2009.

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Organization, World Health, and Conference of Experts on the Rational Use of Drugs (1985 : Nairobi, Kenya), eds. The Rational use of drugs: Report of the conference of experts, Nairobi, 25-29 November 1985. World Health Organization, 1987.

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Michael, Grossman. The demand for cocaine by young adults: A rational addiction approach. National Bureau of Economic Research, 1996.

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Angerer, Erwin von. The estrogen receptor as a target for rational drug design. Springer, 1995.

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Book chapters on the topic "Rational drug use"

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Hindie, Valerie, Laura A. Lopez-Garcia, and Ricardo M. Biondi. "Use of a Fluorescent ATP Analog to Probe the Allosteric Conformational Change in the Active Site of the Protein Kinase PDK1." In Rational Drug Design. Humana Press, 2012. http://dx.doi.org/10.1007/978-1-62703-008-3_10.

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Littmann, Jasper, Annette Rid, and Alena Buyx. "Tackling Anti-microbial Resistance: An Ethical Framework for Rational Antibiotic Use." In Ethics and Drug Resistance: Collective Responsibility for Global Public Health. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-27874-8_20.

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Abstract To reduce the effect of antimicrobial resistance and preserve antibiotic effectiveness, clinical practice guidelines and health policy documents call for the “rational use” of antibiotics that aims to avoid unnecessary or minimally effective antibiotic prescriptions. In this paper, we show that rational use programmes can lead to ethical conflicts because they place some patients at risk of harm – for example, a delayed switch to second-line antibiotics for community-acquired pneumonia is associated with increased fatality rates. Implementing the rational use of antibiotics can theref
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Wong, Adrian, Jonny Wilkinson, Prashant Nasa, Luca Malbrain, and Manu L. N. G. Malbrain. "Introduction to Fluid Stewardship." In Rational Use of Intravenous Fluids in Critically Ill Patients. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-42205-8_27.

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AbstractIntravenous (IV) fluids are commonly prescribed drugs in healthcare. However, inappropriate fluid administration is associated with higher morbidity and mortality. Fluid stewardship is defined as a series of coordinated interventions for judicious IV fluid administration, with a primary goal of limiting the deleterious effects of inappropriate fluid prescription and fluid overload or accumulation and optimizing the clinical outcomes. The success of Stewardships in healthcare can achieve success by strategy and policy development, designing overarching systems, encouraging collaboration
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Lasagna, Louis. "Introduction: The Rational Use of Plasma Drug Levels in Clinical Medicine." In Ciba Foundation Symposium 74 - Drug Concentrations in Neuropsychiatry. John Wiley & Sons, Ltd., 2008. http://dx.doi.org/10.1002/9780470720578.ch1.

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Yeung, John H. K. "New Results on the Pharmacology and Clinical Use of the TCM-Drug Salvia miltiorrhiza." In Evidence and Rational Based Research on Chinese Drugs. Springer Vienna, 2012. http://dx.doi.org/10.1007/978-3-7091-0442-2_6.

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Leal, Mauricio, Avraham Yacobi, and Vijay K. Batra. "Use of Toxicokinetic Principles in Drug Development: Bridging Preclinical and Clinical Studies." In Integration of Pharmacokinetics, Pharmacodynamics, and Toxicokinetics in Rational Drug Development. Springer US, 1993. http://dx.doi.org/10.1007/978-1-4757-1520-0_8.

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Malbrain, Manu L. N. G., Michaël Mekeirele, Matthias Raes, et al. "The 4-indications of Fluid Therapy: Resuscitation, Replacement, Maintenance and Nutrition Fluids, and Beyond." In Rational Use of Intravenous Fluids in Critically Ill Patients. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-42205-8_8.

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AbstractThe administration of intravenous (IV) fluids in critically ill patients remains a major therapeutic challenge. While there are many questions regarding the type, properties, speed, dose, and timing of fluid administration, there are only four major indications for their use: resuscitation, replacement, maintenance, and nutrition. In addition to these indications, IV fluids can also be used as carriers for medications. This chapter not only discusses the major indications for fluid therapy but also delves into different fluid management strategies, including early adequate goal-directe
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Chatterjee, Ranajit, and Ashutosh Kumar Garg. "Nutrition Delivery in Critically Ill Patients." In Rational Use of Intravenous Fluids in Critically Ill Patients. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-42205-8_13.

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AbstractThis chapter discusses the importance of medical nutrition therapy in critically ill patients in the ICU. The goals of nutrition in the ICU include preserving lean body mass, maintaining immune function, and avoiding metabolic complications. The chapter also covers topics such as nutrition assessment, assessment of energy expenditure, starting enteral nutrition, dosing and monitoring of tolerance and adequacy of EN, selection of appropriate EN, indications of parenteral nutrition, diet formulation in special medical conditions, impact of nutrition on fluid therapy and accumulation, and
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Peck, Carl C. "Rationale for the Effective Use of Pharmacokinetics and Pharmacodynamics in Early Drug Development." In Integration of Pharmacokinetics, Pharmacodynamics, and Toxicokinetics in Rational Drug Development. Springer US, 1993. http://dx.doi.org/10.1007/978-1-4757-1520-0_1.

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Rozman, Karl K. "Use of Acute Toxicity Data in the Design and Interpretation of Subchronic and Chronic Toxicity Studies." In Integration of Pharmacokinetics, Pharmacodynamics, and Toxicokinetics in Rational Drug Development. Springer US, 1993. http://dx.doi.org/10.1007/978-1-4757-1520-0_6.

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Conference papers on the topic "Rational drug use"

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Bahce, Asli, Semih Utku, and Canan Eren Atay. "Rational Drug Use and equivalent drugs price analysis in prescription." In 2015 Medical Technologies National Conference (TIPTEKNO). IEEE, 2015. http://dx.doi.org/10.1109/tiptekno.2015.7374559.

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Lopes, Luciane Cruz. "Anais do V International Workshop on Rational Use of Medicines." In V International Workshop on Rational Use of Medicines. Brazilian Journal of Pharmaceutical Science, 2021. http://dx.doi.org/10.46943/v.iwrum.2021.01.

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Producing and sharing knowledge have been the main goals of the Graduate Program in Pharmaceutical Sciences of the University of Sorocaba. With a focus on the rational use of medicines, the importance of the event is justified by highlighting one of the main concerns worldwide, with an important impact on society, health systems, institutions, and communities. The improvement of professional practices depends on the engagement of researchers, health professionals, managers, students, and others interested in improving health policies, programs, services, and actions. Developing and applying sc
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Amer, Samar A., and Sami I. Almudarra. "Assessment of Drug Use Pattern among Hajj Pilgrims Saudi Arabia, 1439h (2018)." In 2nd International Conference on Public Health and Well-being. iConferences (Pvt) Ltd, 2022. http://dx.doi.org/10.32789/publichealth.2021.1009.

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Hajj pilgrimage is the biggest and longest mass gathering, thus increasing the risk of communicable and non-communicable diseases, so this study aimed to promote rational drug use and optimum provision of drugs among Hajj 1439 Pilgrims through the following objectives: To determine the prevalence and the context of the drug's use and to assess the drug use patterns among pilgrims. METHODS: A cross-sectional study was carried out on randomly selected 785 Hajj Pilgrims, stratified according to their countries before their retrial in King Abdul Aziz Airport in Jeddah: The studied pilgrims were 52
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Deng, Zhonghui, Hai Yuan, Wei Feng, Zheng Xu, Jian Wang, and weijun wang. "Second order relation graph embedding neural network for rational drug use prediction." In International Conference on Electronic Information Engineering and Computer Science (EIECS 2022), edited by Yang Yue. SPIE, 2023. http://dx.doi.org/10.1117/12.2668194.

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Elisabeth, Yuliana Helena, and Vetty Yulianty Permanasari. "Rational Drug Use to Increase Service Quality in Developing Countries: A Systematic Review." In The 5th Intenational Conference on Public Health 2019. Masters Program in Public Health, Universitas Sebelas Maret, 2019. http://dx.doi.org/10.26911/mid.icph.2018.02.36.

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Elisabeth, Yuliana Helena, and Vetty Yulianty Permanasari. "Rational Drug Use to Increase Service Quality in Developing Countries: A Systematic Review." In The 5th Intenational Conference on Public Health 2019. Masters Program in Public Health, Universitas Sebelas Maret, 2019. http://dx.doi.org/10.26911/theicph.2019.05.23.

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Yang, G., Z. Wang, L. Chen, and P. Huang. "CP-033 Application analysis of drug rational use management system in a tumour specialised hospital." In 22nd EAHP Congress 22–24 March 2017 Cannes, France. British Medical Journal Publishing Group, 2017. http://dx.doi.org/10.1136/ejhpharm-2017-000640.32.

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He, Yufang, Qian Zhao, Linlin Liu, et al. "The recent research on rational drug use in China-----based on the LDA theme model." In AIIIP 2024: 2024 3rd International Conference on Artificial Intelligence and Intelligent Information Processing. ACM, 2024. https://doi.org/10.1145/3707292.3707339.

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Guryev, D. I., K. M. Verbilo та A. V. Zuraev. "PREDICTION OF BIOLOGICAL ACTIVITY OF 1,4-DISUBSTITUTED 1Н-1,2,3-TRIAZOLE DERIVATIVES BY MOLECULAR DOCKING". У XI МЕЖДУНАРОДНАЯ КОНФЕРЕНЦИЯ МОЛОДЫХ УЧЕНЫХ: БИОИНФОРМАТИКОВ, БИОТЕХНОЛОГОВ, БИОФИЗИКОВ, ВИРУСОЛОГОВ, МОЛЕКУЛЯРНЫХ БИОЛОГОВ И СПЕЦИАЛИСТОВ ФУНДАМЕНТАЛЬНОЙ МЕДИЦИНЫ. IPC NSU, 2024. https://doi.org/10.25205/978-5-4437-1691-6-3.

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In accordance with rational drug discovery methodologies, the antiproliferative activity of 1,4-disubstituted 1H-1,2,3-triazole derivatives was investigated utilizing an in-house prediction algorithm for molecular docking. This prediction algorithm, implemented in existing software to automate routine stages using Python, is designed for universal application, enabling its use with a diverse array of ligands and targets.
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"Proceedings V International Workshop on Rational Use of Medicines; III Worknowledge of Evidence-Informed Police; III Symposium ISPE BrazIntRIG; I Symposium of ISPE Brazilian Student Chapters." In V International Workshop on Rational Use of Medicines; III Worknowledge of Evidence-Informed Police; III Symposium ISPE BrazIntRIG; I Symposium of ISPE Brazilian Student Chapters. Brazilian Journal of Pharmaceutical Sciences, 2021. http://dx.doi.org/10.46943/v.iwrum.2021.02.

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Producing and sharing knowledge have been the main goals of the Graduate Program in Pharmaceutical Sciences of the University of Sorocaba. With a focus on the rational use of medicines, the importance of the event is justified by highlighting one of the main concerns worldwide, with an important impact on society, health systems, institutions, and communities. The improvement of professional practices depends on the engagement of researchers, health professionals, managers, students, and others interested in improving health policies, programs, services, and actions. Developing and applying sc
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Reports on the topic "Rational drug use"

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Krahn, Thomas, Sara Campos, Robert P. Loewe, et al. D5.3 - Initial whitepaper on rational for a wet-lab technology platform for patient recruitment. REPO4EU, 2023. https://doi.org/10.58647/repo4eu.202300d5.3.

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Precision medicine takes patient characteristics and differences on the phenotypic, endotypic and molecular level into account. With the aim to find the right drug for the right patient at the right time, precise diagnosis becomes essential to determine the best treatment for an individual. Diagnostic tests play a crucial role in recruiting the right patients for innovative clinical trials by identifying patients who are most likely to benefit from a specific treatment and who have specific disease characteristics like a molecular mechanism that is being targeted in the trial. Our wet-lab tech
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Johnson, Corey, Colton James, Sarah Traughber, and Charles Walker. Postoperative Nausea and Vomiting Implications in Neostigmine versus Sugammadex. University of Tennessee Health Science Center, 2021. http://dx.doi.org/10.21007/con.dnp.2021.0005.

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Purpose/Background: Postoperative nausea and vomiting (PONV) is a frequent complaint in the postoperative period, which can delay discharge, result in readmission, and increase cost for patients and facilities. Inducing paralysis is common in anesthesia, as is utilizing the drugs neostigmine and sugammadex as reversal agents for non-depolarizing neuromuscular blockers. Many studies are available that compare these two drugs to determine if neostigmine increases the risk of PONV over sugammadex. Sugammadex has a more favorable pharmacologic profile and may improve patient outcomes by reducing P
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Gupta, Aditya, Tong Wang, Shruthi Ravi, Mesbah Talukder, Jessie Carviel, and Mary Bamimore. Relative efficacy of microneedling in the treatment of pattern hair loss: a protocol for a systematic review with network meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.9.0042.

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Review question / Objective: The objective of the proposed study is to determine the relative efficacy of microneedling and combination of it and other agents for androgenetic alopecia (AGA)—a condition that is also referred to as pattern hair loss. Rationale: Pattern hair loss is one of the most common forms of hair loss in men and women; the condition is associated with decreased quality of life. Oral finasteride and topical minoxidil are treatments currently approved, by the United States Food and Drug Administration, for AGA. However, finasteride has been associated with significant side e
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Evidence Synthesis and Meta-Analysis for Drug Safety. Council for International Organizations of Medical Sciences (CIOMS), 2016. http://dx.doi.org/10.56759/lela7055.

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At any point in the drug development process, systematic reviews and meta-analysis can provide important information to guide the future path of the development programme and any actions that might be needed in the post-marketing setting. This report gives the rationale for why and when a meta-analysis should be considered, all in the context of regulatory decision-making, and the tasks, data collection, and analyses that need to be carried out to inform those decisions. -- There is increasing demand by decision-makers in health care, the biopharmaceutical industry, and society at large to hav
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