Relevant bibliographies by topics / Rats as laboratory animals

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Rats as laboratory animals'

Author: Grafiati
Published: 4 June 2021
Last updated: 30 July 2024

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Journal articles on the topic "Rats as laboratory animals"

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Odenweller, C. M., C. T. Hsu, E. Sipe, J. P. Layshock, S. Varyani, R. L. Rosian, and S. E. DiCarlo. "Laboratory exercise using "virtual rats" to teach endocrine physiology." Advances in Physiology Education 273, no. 6 (December 1997): S24. http://dx.doi.org/10.1152/advances.1997.273.6.s24.

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Animal experimentation is limited in many curricula due to the expense, lack of adequate animal facilities and equipment, and limited experience of the teachers. There are also ethical concerns dealing with the comfort and safety of the animals. To overcome these obstacles, we developed a "dry laboratory" using "virtual rats." The "virtual rat" eliminates the obstacles inherent in animal experimentation, such as inadequate budgets, as well as avoiding important animal rights issues. Furthermore, no special materials are required for the completion of this exercise. Our goal in developing this
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Gürlek, Ali. "Rats As Laboratory Animals In Chronic Studies." Plastic & Reconstructive Surgery 100, no. 6 (November 1997): 1618. http://dx.doi.org/10.1097/00006534-199711000-00052.

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Temoçin, Sadun, Hüseyin Beydağı, Sedat Akar, and S. Sadi Kurdak. "Exercise Methods in Small Laboratory Animals (Rats)." European Journal of Therapeutics 5, no. 2 (June 1, 1994): 247–54. http://dx.doi.org/10.58600/eurjther.1994-5-2-1080-arch.

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Lots of study about exercise were performed in recent years. Small laboratory animals, especially rats are used widely in these studies. Several exercise models about small laboratory animals were explained, and some special methodological examples used in physiological research were presented in this review.
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Kunstýř, I., F. Jelínek, U. Bitzenhofer, and W. Pittermann. "Fungus Paecilomyces: a new agent in laboratory animals." Laboratory Animals 31, no. 1 (January 1, 1997): 45–51. http://dx.doi.org/10.1258/002367797780600260.

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The fungus Paecilomyces has not yet been considered a health problem in laboratory animals. However, this agent known as a 'spoiler' of fruit beverages and other foodstuffs is an opportunistic pathogen especially in immunocompromised humans. Since 1985, we have isolated Paecilomyces, most probably P. variotti, from six laboratory animal species, mainly rats. In about 90% of cases the organism was localized in the respiratory tract and there are some other findings favouring the hypothesis of an airborne infection. During this long observation period no consequences for the health of rats in on
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Birke, Lynda. "Who—or What—are the Rats (and Mice) in the Laboratory." Society & Animals 11, no. 3 (2003): 207–24. http://dx.doi.org/10.1163/156853003322773023.

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AbstractThis paper explores the many meanings attached to the designation,"the rodent in the laboratory" (rat or mouse). Generations of selective breeding have created these rodents. They now differ markedly from their wild progenitors, nonhuman animals associated with carrying all kinds of diseases.Through selective breeding, they have moved from the rats of the sewers to become standardized laboratory tools and (metaphorically) saviors of humans in the fight against disease. This paper sketches two intertwined strands of metaphors associated with laboratory rodents.The first focuses on the i
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Dragan, Sergey P., Igor A. Veselovsky, Dmitriy B. Komarov, and Aleksey V. Bogomolov. "METHOD FOR FORMING BEHAVIORAL REACTIONS IN LABORATORY ANIMALS." Siberian Journal of Life Sciences and Agriculture 15, no. 4 (August 30, 2023): 11–28. http://dx.doi.org/10.12731/2658-6649-2023-15-4-11-28.

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Background. The solution of a number of applied problems requires extrapolation of the medical and biological effects of exposure to extreme physical factors from animals on humans based on the results of experimental studies of the behavioral reactions of animals under the influence of such factors. The specificity of such studies is the need for preliminary formation of the necessary behavioral responses in a large group of laboratory animals, which requires significant time costs.
 Purpose. The purpose of the study was to reduce the time of formation of behavioral reactions in laborato
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Jacob, Howard J. "Modern genetic mapping approaches in laboratory animals/rats." Journal of Experimental Animal Science 41, no. 1-2 (March 2000): 32–34. http://dx.doi.org/10.1016/s0939-8600(00)80023-1.

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Chechet, O. M., and V. L. Kovalenko. "Study of the safety and harmlessness of a disinfectant in laboratory animals." Journal for Veterinary Medicine, Biotechnology and Biosafety 8, no. 1-2 (May 10, 2022): 23–29. http://dx.doi.org/10.36016/jvmbbs-2022-8-1-2-4.

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The work aimed to investigate the effect of the disinfectant ‘Diolaid’ based on sodium chlorite and sodium chloride on acute toxicity indicators, as well as on blood parameters of laboratory animals. The experiments were carried out on 6-month-old clinically healthy male rats (5 groups, 6 animals in each group, n = 30) and female rats (5 groups, 6 animals in each group, n = 30) weighing 200–220 g. The drug was administered to animals intragastrically (by probe) and aerosol treatment of cells with animals was carried out. Separately we studied the skin-irritating and sensitizing action of the d
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Bowen, W. H., K. M. Madison, and S. K. Pearson. "Influence of Desalivation in Rats on Incidence of Caries in Intact Cagemates." Journal of Dental Research 67, no. 10 (October 1988): 1316–18. http://dx.doi.org/10.1177/00220345880670101401.

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The evidence that dental caries is an infectious and transmitted disease in rodents is unequivocal. However, the factors controlling the transmission of micro-organisms from one animal to another have not been extensively explored. Results from previous studies in our laboratory showed that desalivated animals became infected by Streptococcus sobrinus in a shorter period of time than did intact animals. Furthermore, an additional study in our laboratory showed that animals with intact salivary function caged with desalivated animals harbored more S. sobrinus immediately following establishment
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Smith, William. "Responses of laboratory animals to some injectable anaesthetics." Laboratory Animals 27, no. 1 (January 1, 1993): 30–39. http://dx.doi.org/10.1258/002367793781082377.

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Xylazine, ketamine, methohexitone and alphadalone/alphaxalone, were administered intraperitoneally, intramuscularly or intravenously to mice, rats, guineapigs and rabbits. Times for disappearance and reappearance of reflexes were recorded, and duration of loss of reflex. Delivering a predetermined dose gave a varying individual response, ranging from inadequate anaesthesia to death. Using reflexes to assess depth of anaesthesia was of limited value. Reflex movements to noxious stimuli generally persisted even at dose rates that caused prolonged recovery times and death. Conversely, in rats the
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Dissertations / Theses on the topic "Rats as laboratory animals"

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Spangenberg, Elin. "Housing laboratory dogs and rats : implications of physical and social activity /." Uppsala : Dept. of Clinical Sciences, Swedish University of Agricultural Sciences, 2007. http://epsilon.slu.se/2007103.pdf.

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Wickens, Nicolas John. "Histopathological changes in male wistar rats maintained on a water-based sutherlandia frutescens extract." Thesis, Nelson Mandela Metropolitan University, 2012. http://hdl.handle.net/10948/4742.

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In this study a standardized 46 week chronic drinking water toxicity protocol was used to elucidate the toxic potential of Sutherlandia frutescens (S. frutescens) using histopathologic, morphometric and transmission electron microscopic analysis. The histopathologic changes in the duodenum, heart, kidney, liver, lung, pancreas and spleen of male Wistar rats were evaluated. Fifty-four rats were randomly divided into four groups: Group 1 – Normal diet control (ND control), n=7, Group 2 – Normal diet + plant extract (ND + p), n=9, Group 3 – High fat diet control (HFD control), n=19Group 4 – High
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Bueno, Aline [UNESP]. "Repercussões de diferentes intensidades glicêmicas no início do desenvolvimento embrionário de ratas." Universidade Estadual Paulista (UNESP), 2012. http://hdl.handle.net/11449/99239.

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Made available in DSpace on 2014-06-11T19:29:52Z (GMT). No. of bitstreams: 0 Previous issue date: 2012-02-10Bitstream added on 2014-06-13T18:59:47Z : No. of bitstreams: 1 bueno_a_me_botfm.pdf: 693767 bytes, checksum: 41a33fd1c28d4062c5457b2ea2de4450 (MD5)<br>Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)<br>In vitro studies suggest that maternal hyperglycemia insult impairs the early embryogenesis in the preimplantation period. In this paper, we show that streptozotocin given at birth day of life or in adulthood of rats caused hyperglycemic state. Regardless of hyperglycemic i
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Xu, Cen Reith Maarten E. A. "Cocaine and the dopamine transporter." Normal, Ill. Illinois State University, 1996. http://wwwlib.umi.com/cr/ilstu/fullcit?p9721400.

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Thesis (Ph. D.)--Illinois State University, 1996.<br>Title from title page screen, viewed May 30, 2006. Dissertation Committee: Maarten E. A. Reith (chair), Hou Tak Cheung, John W. Dailey, Robert L. Preston, Brian J. Wilkinson. Includes bibliographical references and abstract. Also available in print.
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Connolly, Ashley Rex. "Cytokine gene expression in a rat model of polyarthritis /." Title page, contents and abstract only, 1998. http://web4.library.adelaide.edu.au/theses/09PH/09phc75238.pdf.

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Bueno, Aline. "Repercussões de diferentes intensidades glicêmicas no início do desenvolvimento embrionário de ratas /." Botucatu : [s.n.], 2012. http://hdl.handle.net/11449/99239.

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Orientador: Débora Cristina Damasceno<br>Coorientador: Yuri Karen Sinzato<br>Banca: Maria José Sparça Salles<br>Banca: Felipe Perecin<br>Resumo: Não disponível<br>Abstract: In vitro studies suggest that maternal hyperglycemia insult impairs the early embryogenesis in the preimplantation period. In this paper, we show that streptozotocin given at birth day of life or in adulthood of rats caused hyperglycemic state. Regardless of hyperglycemic intensities (mild or severe diabetes), the embryos of these dams presented development retardation and decreased development competence. Apoptosis was det
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Vetter, Courtney Suzanne. "Time-course of elevated ethanol intake in adolescent relative to adult rats under continuous, voluntary-access conditions." Diss., Online access via UMI:, 2006.

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Hu, Dan. "Brain cytochrome oxidase activity related to vicaroius trial-and-error behavior during Y-maze learning in the rat /." Digital version accessible at:, 1999. http://wwwlib.umi.com/cr/utexas/main.

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Kong, Hei-man Lowell, and 江希文. "Adrenomedullin: distribution in the male accessory sex glands of the rat and the effects of adrenomedullin inthe seminal fluid on the female reproductive tract." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B45605671.

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Agnelli, Silvia. "Regulation of amino acid catabolism in rats fed diets with different protein content." Doctoral thesis, Universitat de Barcelona, 2016. http://hdl.handle.net/10803/400005.

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Current lifestyle with high-energy diets and characterized by sedentary is triggering an alarming growth in obesity. Obesity along with metabolic syndrome- related co-morbidities (i.e. insulin resistance, atherosclerosis, sleep apnea, depression, asthma, hypertension and the alteration of blood lipid transport) are the most apparent consequence of the excess energy. Under conditions of excess dietary energy, the body cannot easily dispose of the excess amino-N against the evolutively-adapted schemes that prevent its wastage; thus ammonia and glutamine formation and urea excretion are decreased
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Books on the topic "Rats as laboratory animals"

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A, Suckow Mark, Weisbroth Steven H, and Franklin Craig L, eds. The laboratory rat. Amsterdam: Elsevier Academic Press, 2005.

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Sharp, Patrick E. The laboratory rat. Edited by La Regina Marie C and Suckow Mark A. Boca Raton, Fla: CRC Press, 1998.

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Sharp, Patrick. The laboratory rat. Boca Raton, Fla: CRC Press, 1998.

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Institute of Laboratory Animal Resources (U.S.). Committee on Infectious Diseases of Mice and Rats., ed. Infectious diseases of mice and rats. Washington, D.C: National Academy Press, 1991.

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L, Altman Philip, Biology Databook Editorial Board (U.S.), Federation of American Societies for Experimental Biology., and Pergamon Infoline Incorporated, eds. Pathology of laboratory mice and rats. Bethesda, Md: Federation of American Societies for Experimental Biology, 1985.

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1947-, Kolb Bryan, ed. The behavior of the laboratory rat: A handbook with tests. New York: Oxford University Press, 2005.

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Institute of Laboratory Animal Resources (U.S.). Committee on Infectious Diseases of Mice and Rats., ed. Companion guide to Infectious diseases of mice and rats. Washington, D.C: National Academy Press, 1991.

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Institute of Laboratory Animal Resources (U.S.). Committee on Infectious Diseases of Mice and Rats., ed. Companion guide to Infectious diseases of mice and rats. Washington, D.C: National Academy Press, 1991.

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Yanlin, Wang-Fischer, ed. Manual of stroke models in rats. Boca Raton: Taylor & Francis, 2008.

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1946-, Stinson Sherman F., Schuller Hildegard M, and Reznik Gerd, eds. Atlas of tumor pathology of the Fischer rat. Boca Raton, Fla: CRC Press, 1990.

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Book chapters on the topic "Rats as laboratory animals"

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Cloutier, Sylvie. "Behavioral Biology of Rats." In Behavioral Biology of Laboratory Animals, 113–30. Boca Raton: CRC Press, 2021. http://dx.doi.org/10.1201/9780429019517-9.

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Kaliste, Eila, and Satu Mering. "The welfare of laboratory rats." In The Welfare of Laboratory Animals, 153–80. Dordrecht: Springer Netherlands, 2007. http://dx.doi.org/10.1007/978-1-4020-2271-5_8.

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Geise, W. "Guidelines for the Use and Care of Small Laboratory Animals in Transplantation Research." In Organtransplantation in Rats and Mice, 27–40. Berlin, Heidelberg: Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-642-72140-3_4.

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Mohan, G. H., R. V. Shwetha Reddy, and C. Yogesh. "Management of Specific Pathogen-Free (SPF) Mice and Rats." In Essentials of Laboratory Animal Science: Principles and Practices, 633–53. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-0987-9_26.

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Kasparert-Rittinghausen, J., and F. Deerberg. "Mortality and Tumour Incidence of BDII/Han Rats." In New Developments in Biosciences: Their Implications for Laboratory Animal Science, 425–29. Dordrecht: Springer Netherlands, 1988. http://dx.doi.org/10.1007/978-94-009-3281-4_69.

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Beynen, A. C., V. Baumans, J. W. M. Haas, K. K. van Hellemond, F. R. Stafleu, and G. van Tintelen. "Assessment of Discomfort Induced by Orbital Puncture in Rats." In New Developments in Biosciences: Their Implications for Laboratory Animal Science, 431–36. Dordrecht: Springer Netherlands, 1988. http://dx.doi.org/10.1007/978-94-009-3281-4_70.

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Hirsjärvi, Paula A., and Mirja A. Junnila. "The Effects of Gentling on Open-field Behaviour of Rats." In New Developments in Biosciences: Their Implications for Laboratory Animal Science, 399–403. Dordrecht: Springer Netherlands, 1988. http://dx.doi.org/10.1007/978-94-009-3281-4_64.

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Kramer, Klaas, and René Remie. "Measuring Electrocardiogram and Heart Rate in Small Laboratory Animals with Radio-Telemetry." In Rodent Model as Tools in Ethical Biomedical Research, 187–201. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-11578-8_12.

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van Wouwe, J. P., M. Veldhuizen, and C. J. A. van den Hamer. "Oral 65Zn Loading Test in Rats Fed Iri-Ob Diet with Various Zn Concentrations." In New Developments in Biosciences: Their Implications for Laboratory Animal Science, 419–23. Dordrecht: Springer Netherlands, 1988. http://dx.doi.org/10.1007/978-94-009-3281-4_68.

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Barber, B. R., L. Torielli, M. Ferrandi, P. Ferrari, S. Salardi, P. Parenti, and L. Duzzi. "Investigating Genetic Variability between the MHS Hypertensive Strain of Rats and its Normotensive Control, MNS." In New Developments in Biosciences: Their Implications for Laboratory Animal Science, 191–96. Dordrecht: Springer Netherlands, 1988. http://dx.doi.org/10.1007/978-94-009-3281-4_31.

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Conference papers on the topic "Rats as laboratory animals"

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Caraba, Marioara Nicoleta, Ion Valeriu Caraba, Adrian Sinitean, Gabi Dumitrescu, and Roxana Popescu. "ADMINISTRATION OF OCHRATOXIN A TO LABORATORY ANIMALS AND ITS EFFECTS ON BLOOD PARAMETERS." In 23rd SGEM International Multidisciplinary Scientific GeoConference 2023. STEF92 Technology, 2023. http://dx.doi.org/10.5593/sgem2023/6.1/s25.12.

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Mycotoxins are agents with different and complex chemical structures, with toxic effects for humans and animals. They can be present in feed and food, although in very small quantities, mycotoxins have a negative effect on the health of animals and people. Ochratoxins are mycotoxins intensively studied in recent years due to their toxicity on the animal and human body; these toxins show nephrotoxic, immunotoxic and myelotoxic, neurotoxic and carcinogenic effects. Thirty male rats of the Sprague- Dawley breed were divided into 3 groups who received through feed doses of of ochratoxin A (OTA): 0
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Belova, Y. I., and O. V. Yakovleva. "Analysis of the content of nitric oxide (II) metabolites rats of different ages." In VIII Vserossijskaja konferencija s mezhdunarodnym uchastiem «Mediko-fiziologicheskie problemy jekologii cheloveka». Publishing center of Ulyanovsk State University, 2021. http://dx.doi.org/10.34014/mpphe.2021-27-29.

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Nitrogen monoxide is a gas transmitter that is an important intermediary in many organ systems, especially in the central nervous system. Nitrogen monoxide is involved in the relaxation of smooth vascular muscles, activation of neurons and responsible for the cytotoxicity of macrophages. The study of change nitrogen oxide metabolite concentration helps to determine its effects on human and animal organs. The study was carried out on laboratory animals of different ages. We used a spectrophotometric method to determine the level of metabolites based on the reaction of nitrites to the Griss reag
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"DOSIMETRY EVALUATION OF BIOLOGICALLY EQUIVALENT MULTIFREQUENCY ELECTROMAGNETIC EXPOSURE OF LABORATORY ANIMALS AND HUMAN." In СОВРЕМЕННЫЕ ПРОБЛЕМЫ ЭКОЛОГИИ И ЗДОРОВЬЯ НАСЕЛЕНИЯ. ЭКОЛОГИЯ И ЗДОРОВЬЕ НАСЕЛЕНИЯ. Иркутский научный центр хирургии и травматологии, 2023. http://dx.doi.org/10.12731/978-5-98277-383-8-art21.

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The actual research problem is radiofrequency electromagnetic field biological effect investigations for laboratory animals exposed to human real multi-frequency exposure from 2-4 generations cellular communication base stations simulation. The equivalent exposure prognostic model is proposed on the basis of experimental data of laboratory rats exposed to multi-frequency chronic electromagnetic fields. Dosimetry parameters were used to determine the equivalent total power density. The human exposure durations were determined on the basis of biologically equivalent time scale with different per
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Organ, Adina, Mariana Jian, Vitalie Cobzac, Vladilena Girbu, Tamara Cotelea, Octavian Cirimpei, Veaceslav Kulcitki, and Viorel Nacu. "In vivo studies of lavender extracts for healing thermal injury in rats." In Scientific seminar with international participation "New frontiers in natural product chemistry". Institute of Chemistry, Republic of Moldova, 2023. http://dx.doi.org/10.19261/nfnpc.2023.ab04.

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In recent years, herbal extracts obtained from medicinal plants have gained increasing interest in treatment of wounds. About 450 plant species having wound healing properties have been identified. The present knowledge of the wound healing process comprises coagulation, inflammation, proliferation, formation and accumulation of fibrous tissues, collagen deposition, epithelialization, contraction of wound with formation of granulation tissues, remodeling and maturation [1]. The selection of research methods was carried out in accordance with objectives of the work: determining of regeneration
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Almakaeva, D. S. "Effect of alcohol on cognitive functions of rats." In SPbVetScience. FSBEI HE St. Petersburg SUVM, 2023. http://dx.doi.org/10.52419/3006-2023-11-4-8.

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The effect of alcohol on the cognitive abilities of laboratory rats was studied. Individuals systematically received small doses of alcohol for a long time (4 months). Throughout the study, the results of the cognitive functions of animals were recorded, namely the ability to navigate in space and motor activity. At 1 month of alcohol intake, the cognitive abilities of the studied individuals improved significantly, but by the end of the experiment, the experimental subjects showed significantly lower results, thereby revealing the negative effects of alcohol on the body.
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Belaya, О. V. "EXPERIMENTAL STUDY OF 2-5G BASE STATION ELECTROMAGNETIC FIELD CHRONIC EXPOSURE NERVOUS SYSTEM EFFECT TYPOLOGICAL FEATURES." In The 4th «OCCUPATION and HEALTH» International Youth Forum (OHIYF-2022). FSBSI «IRIOH», 2022. http://dx.doi.org/10.31089/978-5-6042929-6-9-2022-1-20-24.

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Introduction: the new exposure to electromagnetic fields biological effect assessment is actual with respect to the expected of electromagnetic environment complication due to joint operation of various generation cellular communication systems. The character of biological reaction can be mediated by individual typological characteristics of the organism. The goal: to study the 2–5G base stations electromagnetic field chronic exposure effect to nervous system functional state of laboratory animals with regard to their typological features. Methods: the rats body weight registration and "open f
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Veshchemova, T. E., and G. V. Masaltsev. "EVALUATION OF TOXICITY AND ANTICHOLINESTERASE EFFECT OF A METHOMYL-CONTAINING DRUG WHEN ADMINISTERED TO LABORATORY ANIMALS VIA VARIOUS ROUTES." In The 4th «OCCUPATION and HEALTH» International Youth Forum (OHIYF-2022). FSBSI «IRIOH», 2022. http://dx.doi.org/10.31089/978-5-6042929-6-9-2022-1-44-48.

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Despite a wide range of insecticidal activity and high efficiency, carbamate insecticides require a highly professional approach to its use due to inherent high toxicity to bees, warm-blooded animals and humans, and undesirable feature of its exhibiting toxic properties not immediately, but after prolonged systematic contact. The goal of this work was to evaluate the toxicity of the methomyl-based drug (25% of the active substance) and its anticholinesterase effect in animal experiments when administered via various routes (rats and rabbits). Materials and methods: Experimental toxicological s
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Perov, S. Yu, and S. A. Askerova. "THE NEUROENDOCRINE SYSTEM RESPONSE OF 2-5 G COMMUNICATION ELECTROMAGNETIC FIELD ANIMAL EXPOSURE." In The 16th «OCCUPATION and HEALTH» Russian National Congress with International Participation (OHRNC-2021). FSBSI “IRIOH”, 2021. http://dx.doi.org/10.31089/978-5-6042929-2-1-2021-1-398-402.

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Abstract: Background. The neuroendocrine effect on the hypothalamus-pituitary-adrenal cortex axis is significant example stressor of electromagnetic exposure for biological object. Aim. The neuroendocrine effect investigation of multi-frequency electromagnetic field laboratory animals’ exposure from 2-5 generations cellular base stations Methods. The neuroendocrine status evaluated by corticosterone and adrenocorticotropic hormone (ACTH) concentrations in blood exposed and sham rats. ACTH and corticosterone rat blood assessed by immunoenzyme method. Results. The results of the multi-frequency
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Shestakov, N. A., R. I. Aizman, A. S. Ogudov, and N. F. Chuenko. "Effect of combined action of arsenic and antimony compounds on renal function in the subchronic test." In VIII Vserossijskaja konferencija s mezhdunarodnym uchastiem «Mediko-fiziologicheskie problemy jekologii cheloveka». Publishing center of Ulyanovsk State University, 2021. http://dx.doi.org/10.34014/mpphe.2021-239-242.

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The study was conducted on male Wistar rats. We used 4 mathematically related series of doses prepared by sequential dilution of water from a man-made lake according to the scheme: arsenic: 0.15 - 0.05 - 0.016 - 0.0055, antimony: 0.68 - 0.227 - 0.075 - 0.025 mg/l. The animals were examined before inoculation (background), on days 40 and 90 of the experiment, taking into account the processes of cumulation of chemical elements in the kidneys. New data on the nature of nephrotoxic effects of arsenic and antimony in the long-term combined intake into the body of laboratory animals have been obtai
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Lanets, O. V., M. P. Semenenko, K. A. Semenenko, and L. V. Lazarevich. "ASSESSMENT OF THE INFLUENCE OF THE NEW STRESS CORRECTOR ON THE LABORATORY ANIMAL ORGANISM IN THE ACUTE EXPERIMENT." In STATE AND DEVELOPMENT PROSPECTS OF AGRIBUSINESS Volume 2. DSTU-Print, 2020. http://dx.doi.org/10.23947/interagro.2020.2.680-682.

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The article presents the results of acute toxicity of a new complex preparation in various ways of its introduction to laboratory white mice and rats. It was determined that a single intragastric and intramuscular administration of the maximum doses of the preparation does not cause a clinical picture of toxicosis and death of laboratory animals, on the basis of which the preparation is classified as hazardous class (GOST 12.1.007-76 “Harmful substances”) - low-hazard substances.
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Reports on the topic "Rats as laboratory animals"

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Matthew, Gray. Data from "Winter is Coming – Temperature Affects Immune Defenses and Susceptibility to Batrachochytrium salamandrivorans". University of Tennessee, Knoxville Libraries, January 2021. http://dx.doi.org/10.7290/t7sallfxxe.

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Environmental temperature is a key factor driving various biological processes, including immune defenses and host-pathogen interactions. Here, we evaluated the effects of environmental temperature on the pathogenicity of the emerging fungus, Batrachochytrium salamandrivorans (Bsal), using controlled laboratory experiments, and measured components of host immune defense to identify regulating mechanisms. We found that adult and juvenile Notophthalmus viridescens died faster due to Bsal chytridiomycosis at 14 ºC than at 6 and 22 ºC. Pathogen replication rates, total available proteins on the sk
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Zurlo, Joanne. Institute of Laboratory Animals Research (ILAR). Fort Belvoir, VA: Defense Technical Information Center, March 2003. http://dx.doi.org/10.21236/ada416653.

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Dechow, Chad Daniel, M. Cohen-Zinder, Morris Soller, Y. Tzfati, A. Shabtay, E. Lipkin, T. Ott, and W. Liu. Genotypes and phenotypes of telomere length in Holstein cattle, actors or reporters. Israel: United States-Israel Binational Agricultural Research and Development Fund, 2020. http://dx.doi.org/10.32747/2020.8134156.bard.

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Selection programs aiming at improving health and survival in cattle are complicated by low heritability estimates, the fact that true herd life and carcass quality is not known until the end of an animal's life, and that many health conditions manifest late in life. Young animals are now heavily favored in breeding programs because low generation intervals accelerate the rate of genetic progress, which means selection decisions must be made before phenotypic observation of health and survival is feasible. Moreover, profitability is compromised when livestock producers raise animals that fail
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Shpigel, Nahum, Raul Barletta, Ilan Rosenshine, and Marcelo Chaffer. Identification and characterization of Mycobacterium paratuberculosis virulence genes expressed in vivo by negative selection. United States Department of Agriculture, January 2004. http://dx.doi.org/10.32747/2004.7696510.bard.

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Mycobacterium avium subsp. paratuberculosis (MAP) is the etiological agent of a severe inflammatory bowel disease (IBD) in ruminants, known as Johne’s disease or paratuberculosis. Johne’s disease is considered to be one of the most serious diseases affecting dairy cattle both in Israel and worldwide. Heavy economic losses are incurred by dairy farmers due to the severe effect of subclinical infection on milk production, fertility, lower disease resistance and early culling. Its influence in the United States alone is staggering, causing an estimated loss of $1.5 billion to the agriculture indu
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Shantyz, A. K., P. V. Miroshnichenko, E. S. Sadikova, and V. V. Menshenin. Changes in hematological and biochemical blood parameters in laboratory animals with experimental escherichiosis. Краснодарский научный центр по зоотехнии и ветеринарии, 2018. http://dx.doi.org/10.18411/88sh-e5337.

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Lahav, Ori, Albert Heber, and David Broday. Elimination of emissions of ammonia and hydrogen sulfide from confined animal and feeding operations (CAFO) using an adsorption/liquid-redox process with biological regeneration. United States Department of Agriculture, March 2008. http://dx.doi.org/10.32747/2008.7695589.bard.

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The project was originally aimed at investigating and developing new efficient methods for cost effective removal of ammonia (NH₃) and hydrogen sulfide (H₂S) from Concentrated Animal Feeding Operations (CAFO), in particular broiler and laying houses (NH₃) and hog houses (H₂S). In both cases, the principal idea was to design and operate a dedicated air collection system that would be used for the treatment of the gases, and that would work independently from the general ventilation system. The advantages envisaged: (1) if collected at a point close to the source of generation, pollutants would
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Corscadden, Louise, and Arpaporn Sutipatanasomboon. What Is Operant Behavior And How To Study It. Maze Engineers, December 2022. http://dx.doi.org/10.55157/me2022127.

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Operant behavior describes a type of voluntary goal-directed actions in animals based on the repercussions of previous occurrences. It develops when animals learn to specifically respond to recurring situations based on the outcome of their past experience. American psychologist B.F. Skinner was the first to use operant to describe the behaviors he observed in his landmark experiments in laboratory animals. Operant behavior and conditioning refine the nuance between conscious and unconscious behavioral responses, which influence psychology, and applied behavior analysis, and improve our unders
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Corscadden, Louise, and Arpaporn Sutipatanasomboon. Rodent Tagging And Identification. ConductScience, January 2023. http://dx.doi.org/10.55157/cs20230109.

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Animal tagging is a means to identify and distinguish all the individual animals of interest, which applies to wildlife, farm, or laboratory animals. It involves attaching a tag to a specific animal part that contains a unique identifier for each animal. The identifier can be numbers, alphabets, or a combination of both that distinguish and track the animals throughout their lifespans. In rodents, tagging is the most popular identification approach. Typically, tags are made from metals and attached to the outer part of rodent ears, or the ear pinna. In rare circumstances, metal tags can also b
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Morrison, Mark, and Joshuah Miron. Molecular-Based Analysis of Cellulose Binding Proteins Involved with Adherence to Cellulose by Ruminococcus albus. United States Department of Agriculture, November 2000. http://dx.doi.org/10.32747/2000.7695844.bard.

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At the beginning of this project, it was clear that R. albus adhered tightly to cellulose and its efficient degradation of this polysaccharide was dependent on micromolar concentrations of phenylacetic acid (PAA) and phenylpropionic acid (PPA). The objectives for our research were: i) to identify how many different kinds of cellulose binding proteins are produced by Ruminococcus albus; ii) to isolate and clone the genes encoding some of these proteins from the same bacterium; iii) to determine where these various proteins were located and; iv) quantify the relative importance of these proteins
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Jung, Carina, Matthew Carr, Denise Lindsay, Eric Fleischman, and Chandler Roesch. Microbiome perturbations during domestication of the green June beetle (Cotinis nitida). Engineer Research and Development Center (U.S.), February 2022. http://dx.doi.org/10.21079/11681/43342.

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Animal-associated microbiomes are critical to the well-being and proper functioning of the animal host, but only limited studies have examined in-sect microbiomes across different developmental stages. These studies revealed large shifts in microbiome communities, often because of significant shifts in diet during insects’ life cycle. Establishing insect colonies as model laboratory organisms and understanding how to properly feed and care for animals with complex and dynamic life cycles requires improved data. This study examined laboratory raised green June beetles (Cotinis nitida) captured
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