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Journal articles on the topic 'Rats Diseases'

Author: Grafiati

Published: 4 June 2021

Last updated: 30 January 2023

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1

Benato, Livia. "Respiratory diseases in rats." Companion Animal 17, no. 4 (May 2012): 47–50. http://dx.doi.org/10.1111/j.2044-3862.2012.00163.x.

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2

Rao, Ghanta N. "Diet and Kidney Diseases in Rats." Toxicologic Pathology 30, no. 6 (October 2002): 651–56. http://dx.doi.org/10.1080/01926230290166733.

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3

Middleton, Charles C. "Infectious Diseases of Mice and Rats. The Committee on Infectious Diseases of Mice and Rats.Companion Guide to Infectious Diseases of Mice and Rats. The Committee on Infectious Diseases of Mice and Rats." Quarterly Review of Biology 67, no. 2 (June 1992): 219. http://dx.doi.org/10.1086/417602.

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4

Clement, Jan, James LeDuc, Graham Lloyd, Jean-Marc Reynes, Lorraine McElhinney, Marc Van Ranst, and Ho-Wang Lee. "Wild Rats, Laboratory Rats, Pet Rats: Global Seoul Hantavirus Disease Revisited." Viruses 11, no. 7 (July 17, 2019): 652. http://dx.doi.org/10.3390/v11070652.

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Recent reports from Europe and the USA described Seoul orthohantavirus infection in pet rats and their breeders/owners, suggesting the potential emergence of a “new” public health problem. Wild and laboratory rat-induced Seoul infections have, however, been described since the early eighties, due to the omnipresence of the rodent reservoir, the brown rat Rattus norvegicus. Recent studies showed no fundamental differences between the pathogenicity and phylogeny of pet rat-induced Seoul orthohantaviruses and their formerly described wild or laboratory rat counterparts. The paucity of diagnosed S

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5

HART, BENJAMIN L., ELIZABETH K. KORINEK, and PATRICIA L. BRENNAN. "Postcopulatory Grooming in Male Rats Prevents Sexually Transmitted Diseases." Annals of the New York Academy of Sciences 525, no. 1 Neural Mechan (May 1988): 397–98. http://dx.doi.org/10.1111/j.1749-6632.1988.tb38624.x.

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6

Wang, Ruwen, Haili Tian, Dandan Guo, Qianqian Tian, Ting Yao, and Xingxing Kong. "Impacts of exercise intervention on various diseases in rats." Journal of Sport and Health Science 9, no. 3 (May 2020): 211–27. http://dx.doi.org/10.1016/j.jshs.2019.09.008.

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7

Casili, Giovanna, Alessio Ardizzone, Marika Lanza, Enrico Gugliandolo, Marco Portelli, Angela Militi, Salvatore Cuzzocrea, Emanuela Esposito, and Irene Paterniti. "Treatment with Luteolin Improves Lipopolysaccharide-Induced Periodontal Diseases in Rats." Biomedicines 8, no. 10 (October 21, 2020): 442. http://dx.doi.org/10.3390/biomedicines8100442.

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Periodontitis is a dental disease that produces the progressive destruction of the bone surrounding the tooth. Especially, lipopolysaccharide (LPS) is involved in the deterioration of the alveolar bone, inducing the release of pro-inflammatory mediators, which cause periodontal tissue inflammation. Luteolin (Lut), a molecule of natural origin present in a large variety of fruits and vegetables, possess beneficial properties for human health. On this basis, we investigated the anti-inflammatory properties of Lut in a model of periodontitis induced by LPS in rats. Animal model predicted a single

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8

ABRAMSKY, O., E. WERTMAN, A. RECHES, T. BRENNER, and H. OVADIA. "Effect of Hypothalamic Lesions on Experimental Autoimmune Diseases in Rats." Annals of the New York Academy of Sciences 496, no. 1 Neuroimmune I (May 1987): 360–65. http://dx.doi.org/10.1111/j.1749-6632.1987.tb35788.x.

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9

SASA, Hiroaki, Yukiya HASHIMOTO, Takako SHIMIZU, and Ken-ichi INUI. "Hepatic Extraction of Tacrolimus in Rats with Experimental Liver Diseases." Biological & Pharmaceutical Bulletin 21, no. 6 (1998): 610–14. http://dx.doi.org/10.1248/bpb.21.610.

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10

Cintra, Luciano Tavares Angelo, Aguinaldo Cândido da Silva Facundo, Mariane Maffei Azuma, Dóris Hissako Sumida, Rafael Dias Astolphi, Suely Regina Mogami Bomfim, Luís Gustavo Narciso, and João Eduardo Gomes-Filho. "Pulpal and periodontal diseases increase triglyceride levels in diabetic rats." Clinical Oral Investigations 17, no. 6 (October 5, 2012): 1595–99. http://dx.doi.org/10.1007/s00784-012-0853-7.

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11

CANDIDO, E., C. CARVALHO, F. MARTINEZ, and V. CAGNON. "Experimental alcoholism and pathogenesis of prostatic diseases in UChB rats." Cell Biology International 31, no. 5 (May 2007): 459–72. http://dx.doi.org/10.1016/j.cellbi.2006.11.009.

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12

Baykal, Asli, Figen S. arigul, Gultekin Suleymanla, Paula I. Moreira, George Perry, Mark A. Smith, and Yakup Aliciguzel. "Ciprofloxacin Does Not Exert Nephrotoxicity in Rats." American Journal of Infectious Diseases 1, no. 3 (March 1, 2005): 145–48. http://dx.doi.org/10.3844/ajidsp.2005.145.148.

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13

Zhao, Na, Zhidan Sun, Ulrich Egert, Yuying Mao, Pengzhou Hang, Xing Jiang, Lihua Sun, Jinlong Zhao, and Zhimin Du. "Myocardial Iron Metabolism in the Regulation of Cardiovascular Diseases in Rats." Cellular Physiology and Biochemistry 25, no. 6 (2010): 587–94. http://dx.doi.org/10.1159/000315077.

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14

Galvão, Mariane Ponzio de Azevedo, Ana Chapper, Cassiano Kuchenbecker Rösing, Maria Beatriz Cardoso Ferreira, and Maria Antonieta Lopes de Souza. "Methodological considerations on descriptive studies of induced periodontal diseases in rats." Pesquisa Odontológica Brasileira 17, no. 1 (March 2003): 56–62. http://dx.doi.org/10.1590/s1517-74912003000100011.

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The aim of this study was to show the technique and the methodological approach used in describing histological characteristics of induced periodontal disease in rats. To reach that inflammatory process, periodontal disease was induced by ligature, with or without sucrose-rich diet. Twenty-four female adult (60 days old) Wistar rats were divided in four groups: Group 1, or control (which received standard diet), Group 2 (which received ligature around the upper second molars and a standard diet), Group 3 (which received a sucrose-rich diet), and Group 4 (which received ligature around the uppe

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15

KIMURA, Toshikiro, Seiya NAKAYAMA, Tadanao YAMAO, Yuji KUROSAKI, and Taiji NAKAYAMA. "Pharmacokinetics of Indocyanine Green in Rats with Experimentally Induced Hepatic Diseases." Biological & Pharmaceutical Bulletin 16, no. 11 (1993): 1140–45. http://dx.doi.org/10.1248/bpb.16.1140.

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16

Orbak, R., C. Kara, E. Özbek, A. Tezel, and T. Demir. "Effects of zinc deficiency on oral and periodontal diseases in rats." Journal of Periodontal Research 42, no. 2 (April 2007): 138–43. http://dx.doi.org/10.1111/j.1600-0765.2006.00939.x.

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17

G.O., Khidirova, Khasanov K.D., Erkinova Dilrabo, and Abdurakhmanova Nafosat. "MORPHOLOGICAL STRUCTURE OF THE FEMUR IN WHITE RATS WITH HYPOPARATHYROIDISM." American Journal of Medical Sciences and Pharmaceutical Research 04, no. 04 (April 1, 2022): 11–15. http://dx.doi.org/10.37547/tajmspr/volume04issue04-03.

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The disease of the musculoskeletal system in children of the first months of life is quite a lot, deformities of the lower extremities are most common. The reason for the observed deformities of the lower extremities is the delay in the development of the bone skeleton during fetal life, due to heredity, infectious diseases of the mother during pregnancy, endocrine pathologies, toxicosis (especially the first half of pregnancy). Many authors, studying the endocrine status of patients with deformities of the lower extremities, came to the conclusion that this pathology is hormonal and mainly de

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18

LOTH, Eduardo Alexandre, Vanessa CECATTO, Samia Khalil BIAZIM, José Henrique Fermino FERREIRA, Caroline DANIELLI, Rodrigo Daniel GENSKE, Rinaldo Ferreira GANDRA, and Marcello Fabiano de FRANCO. "EXPERIMENTAL PARACOCCIDIOIDOMYCOSIS IN PREGNANT RATS." Revista do Instituto de Medicina Tropical de São Paulo 57, no. 6 (December 2015): 515–18. http://dx.doi.org/10.1590/s0036-46652015000600010.

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Paracoccidioidomycosis (PCM), caused by the dimorphic fungus Paracoccidioides brasiliensis (Pb), is the most prevalent systemic mycosis in Latin America. There are few reports in the literature about the disease damages during pregnancy and the consequences to the fetuses and breeding. This study evaluated the implications of PCM during pregnancy on offspring and mothers in Wistar rats. Groups of rats were submitted to systemic Pb infection, by intraperitoneal infusion, and mated 30 days after the infection date. Immediately after birth, rats and neonates were sacrificed to obtain organs for s

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19

Nakamura, Y., T. Masuhara, S. Ito-Kuwa, and S. Aoki. "Induction of experimentalCandidaarthritis in rats." Medical Mycology 29, no. 3 (January 1991): 179–92. http://dx.doi.org/10.1080/02681219180000281.

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20

Oliynyk, Zh. "LONG-TERM EFFECTS OF SHAM SURGERY ON PHAGOCYTE FUNCTIONS IN RATS." Biotechnologia Acta 15, no. 2 (April 2022): 37–46. http://dx.doi.org/10.15407/biotech15.02.037.

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Animal models of inflammatory disorders, including those of the nervous system are commonly used to explore the pathophysiological role of immune cell response in disease triggering and course and to develop biotechnology products for therapeutic use. Modeling some of these disorders, particularly neurodegenerative diseases, implies surgical manipulations for the intracerebral introduction of disease-initiating substances (toxins, amyloids etc.). Design of these experiments involves the use of sham-operated animals as a control of non-specific intrinsic side-effects elicited by surgical manipu

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21

Güngör, M., H. Sagduyu, H. Koyuncuoglu, Ö. Ang, V. Uysal, D. Inanç, and M. Ang. "Comparison of the development of experimental pyelonephritis in homozygous brattleboro diabetes insipidus rats, heterozygous control rats and normal wistar rats." Infection 13, no. 2 (March 1985): 82–84. http://dx.doi.org/10.1007/bf01660420.

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22

Hong, S. T., B. I. Kim, W. G. Kho, J. R. Yu, J. Kook, J. Y. Chai, C. K. Yun, and S. H. Lee. "Karyotypes of Pneumocystis carinii from Korean rats." Korean Journal of Parasitology 30, no. 3 (1992): 183. http://dx.doi.org/10.3347/kjp.1992.30.3.183.

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23

Hong, S. T. "PCR in diagnosis of pneumocystosis of rats." Korean Journal of Parasitology 34, no. 3 (1996): 191. http://dx.doi.org/10.3347/kjp.1996.34.3.191.

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24

Sengor, B., D. Bayramgurler, B. Muezzinoglu, L. Altintas, N. Bilen, and R. Apaydin. "Effects of acitretin on spermatogenesis of rats." Journal of the European Academy of Dermatology and Venereology 20, no. 6 (July 2006): 689–92. http://dx.doi.org/10.1111/j.1468-3083.2006.01573.x.

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25

Galbe, Jordi L., Edward Guy, Jose M. Zapatero, Ellinor I. B. Peerschke, and Jorge L. Benach. "Vascular clearance of Borrelia burgdorferi in rats." Microbial Pathogenesis 14, no. 3 (March 1993): 187–201. http://dx.doi.org/10.1006/mpat.1993.1019.

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26

Gottberg, Carlos F., Jose H. Donis, Argenis Torres, Abdel J. Fuenmayor, and Diego F. Davila. "Heart rate changes in rats with acute Chagasic myocarditis." Transactions of the Royal Society of Tropical Medicine and Hygiene 82, no. 6 (November 1988): 851. http://dx.doi.org/10.1016/0035-9203(88)90014-4.

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27

Schmidt, A. "Systemic candidiasis in Sprague-Dawley rats." Medical Mycology 34, no. 2 (January 1996): 99–104. http://dx.doi.org/10.1080/02681219680000151.

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28

Sobel, Jack D., Gregory Muller, and John F. McCormick. "Experimental chronic vaginal candidosis in rats." Medical Mycology 23, no. 3 (January 1985): 199–206. http://dx.doi.org/10.1080/00362178585380301.

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29

Komninou, Despina, Virginia L. Malloy, Jay A. Zimmerman, Raghu Sinha, and John P. Richie. "Methionine restriction delays aging-related urogenital diseases in male Fischer 344 rats." GeroScience 42, no. 1 (November 14, 2019): 287–97. http://dx.doi.org/10.1007/s11357-019-00129-4.

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30

Quiros, J., J. Gonzalez-cabrerot, G. Herrero-beaumont, and J. Egido. "Elevated Plasma Fibronectin Levels in Rats with Immune and Toxic Glomerular Diseases." Renal Failure 12, no. 4 (January 1990): 227–32. http://dx.doi.org/10.3109/08860229009060729.

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31

Zykova, Svetlana, Sergey Shurov, Aleksey Savinkov, Nino Gugushvili, and Vladimir Talismanov. "Pharmacoprophylaxis of liver diseases: creating a new hepatoprotector." BIO Web of Conferences 17 (2020): 00061. http://dx.doi.org/10.1051/bioconf/20201700061.

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The article presents a study of the hepatoprotective activity of a tricyclic heterocycle, which refers to 5, 6, 7, 8-tetrahydroquinolines. The effect of 8, 8-dimethyl-5-p-tolyl-8, 9-dihydro-2H-pyrido [4, 3, 2-de] cinnolin-3 (7H) was studied on rats under the influence of the model of toxic hepatosis induced by carbon tetrachloride to find out the indicators of peroxidation and biochemical indicators. Biochemical studies have shown that modelling toxic fat hepatosis caused by the inception of carbon tetrachloride to rats increased the activity of alanine aminotransferase by 2.5 times more compa

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32

Yasuda, Shumpei P., Kenta Shimizu, Takaaki Koma, Nguyen Thuy Hoa, Mai Quynh Le, Zhuoxing Wei, Devinda S. Muthusinghe, et al. "Immunological Responses to Seoul Orthohantavirus in Experimentally and Naturally Infected Brown Rats (Rattus norvegicus)." Viruses 13, no. 4 (April 12, 2021): 665. http://dx.doi.org/10.3390/v13040665.

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To clarify the mechanism of Seoul orthohantavirus (SEOV) persistence, we compared the humoral and cell-mediated immune responses to SEOV in experimentally and naturally infected brown rats. Rats that were experimentally infected by the intraperitoneal route showed transient immunoglobulin M (IgM) production, followed by an increased anti-SEOV immunoglobulin G (IgG) antibody response and maturation of IgG avidity. The level of SEOV-specific cytotoxic T lymphocytes (CTLs) peaked at 6 days after inoculation and the viral genome disappeared from serum. In contrast, naturally infected brown rats si

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33

Hong, S. J., H. C. Woo, J. Y. Chai, S. W. Chung, S. H. Lee, and B. S. Seo. "Study on Centrocestus armatus in Korea. II. Recovery rate, growth and development of worms in albino rats." Korean Journal of Parasitology 27, no. 1 (1989): 47. http://dx.doi.org/10.3347/kjp.1989.27.1.47.

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34

Hong, S. J., H. C. Woo, S. Y. Lee, J. H. Ahn, C. K. Park, J. Y. Chai, and S. H. Lee. "Worm recovery rate and small intestinal lesions of albino rats coinfected with Fibricola seoulensis and Metagonimus yokogawai." Korean Journal of Parasitology 31, no. 2 (1993): 109. http://dx.doi.org/10.3347/kjp.1993.31.2.109.

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35

Ohta, Takeshi, Yoshiaki Katsuda, Katsuhiro Miyajima, Tomohiko Sasase, Shuichi Kimura, Bin Tong, and Takahisa Yamada. "Gender Differences in Metabolic Disorders and Related Diseases in Spontaneously Diabetic Torii-LeprfaRats." Journal of Diabetes Research 2014 (2014): 1–7. http://dx.doi.org/10.1155/2014/841957.

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The Spontaneously Diabetic ToriiLeprfa(SDT fatty) rat is a novel type 2 diabetic model wherein both male and female rats develop glucose and lipid abnormalities from a young age. In this study, we investigated gender differences in abnormalities and related complications in SDT fatty rats. Food intake was higher in males compared to female rats; however, body weight was not different between genders. Progression of diabetes, including increases in blood glucose and declines in blood insulin, was observed earlier in male rats than in females, and diabetic grade was more critical in male rats. B

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36

Hong, Sung-Tae, Yun-Kyu Park, Jin Kim, Dug-Ha Kim, and Chong-Ku Yun. "Is Pneumocystis carinii vertically transmitted to neonatal rats?" Korean Journal of Parasitology 37, no. 3 (1999): 149. http://dx.doi.org/10.3347/kjp.1999.37.3.149.

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37

Nielsen, Susanne Schouw, Thorbjørn Grøfte, Niels Tygstrup, and Hendrik Vilstrup. "Cirrhosis and endotoxin decrease urea synthesis in rats." Hepatology Research 37, no. 7 (July 2007): 540–47. http://dx.doi.org/10.1111/j.1872-034x.2007.00076.x.

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38

Lian-Chen, Wang, Chao David, and Chen Eng-Rin. "Acquired immunity in rats against Angiostrongylus cantonensis infection." International Journal for Parasitology 19, no. 6 (September 1989): 617–20. http://dx.doi.org/10.1016/0020-7519(89)90039-8.

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39

Weissenbacher, Mercedes C., Eduardo F. Lascano, María M. Avila, and María I. Berría. "Chronic Neurologic Disease in Junín Virus-Infected Rats." Journal of Medical Virology 20, no. 1 (September 1986): 57–65. http://dx.doi.org/10.1002/jmv.1890200108.

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40

Temma, Takashi, Kazuhiro Koshino, Tetsuaki Moriguchi, Jun-ichiro Enmi, and Hidehiro Iida. "PET Quantification of Cerebral Oxygen Metabolism in Small Animals." Scientific World Journal 2014 (2014): 1–7. http://dx.doi.org/10.1155/2014/159103.

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Understanding cerebral oxygen metabolism is of great importance in both clinical diagnosis and animal experiments because oxygen is a fundamental source of brain energy and supports brain functional activities. Since small animals such as rats are widely used to study various diseases including cerebral ischemia, cerebrovascular diseases, and neurodegenerative diseases, the development of a noninvasivein vivomeasurement method of cerebral oxygen metabolic parameters such as oxygen extraction fraction (OEF) and cerebral metabolic rate of oxygen (CMRO2) as well as cerebral blood flow (CBF) and c

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41

Stahlmann, R., S. Klug, C. Lewandowski, I. Chahoud, G. Bochert, H. J. Merker, and D. Neubert. "Teratogenicity of acyclovir in rats." Infection 15, no. 4 (July 1987): 261–62. http://dx.doi.org/10.1007/bf01644129.

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42

Shinozaki, Kazuya, Atsunori Kashiwagi, Masahiro Masada, and Tomio Okamura. "Tetrahydrobiopterin and Endothelial Dysfunction in Cardiovascular Diseases." Pteridines 17, no. 1 (February 2006): 11–15. http://dx.doi.org/10.1515/pteridines.2006.17.1.11.

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Abstract Endothelial vasodilator dysfunction is a characteristic feature of patients at risk for coronary atheroscierosis. We have reported that insulin resistance may be a pathogenic factor for endothehal dysfunction through impaired endothelial nitric oxide synthase (eNOS) activity and increased oxidative breakdown of nitric oxide (NO) due to an enhanced fonnation of Superoxide anion, which arc caused by relative deficiency of tetrahydrobiopterin (BH4) in vascular endothelial cclls. Guanosine-triphosphate cyclohydrolase I, the rate-limiting cnzyme in the production of BH4, is decreased in th

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43

YOUSFI, Mimoun EL, Denis BREUILLÉ, Isabelle PAPET, Stéphanie BLUM, Marc ANDRÉ, Laurent MOSONI, Philippe DENIS, Caroline BUFFIÈRE, and Christiane OBLED. "Increased tissue protein synthesis during spontaneous inflammatory bowel disease in HLA-B27 rats." Clinical Science 105, no. 4 (October 1, 2003): 437–46. http://dx.doi.org/10.1042/cs20020313.

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Inflammatory bowel diseases (IBDs) are associated with an increased whole-body protein turnover. In certain drug-induced experimental models of IBD, disturbances of protein synthesis in tissues have been reported recently, but it is unclear if similar disturbances occur in other chronic intestinal diseases. Therefore we investigated changes in protein synthesis in different tissues of HLA-B27 (human leucocyte antigen B27) transgenic rats that develop spontaneously chronic inflammation, with major involvement of the colon. Protein synthesis rate in HLA-B27 rats was shown to be higher in nine di

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44

Berahmand, Farnoosh, Golnoush Anoush, Mir-Jamal Hosseini, and Mahdieh Anoush. "Grape Seed Oil as a Natural Therapy in Male Rats with Alzheimer’s Diseases." Advanced Pharmaceutical Bulletin 10, no. 3 (May 11, 2020): 430–36. http://dx.doi.org/10.34172/apb.2020.052.

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Purpose: Alzheimer’s disease (AD) is a chronic neurodegenerative disorder, with an increasing prevalence rate, mostly related to cholinergic system. According to the difficulties and complications in management of AD, this study was carried out to evaluate the efficacy of grape seed oil (GSO) on scopolamine (Scop) induced Alzheimer’s in male rats. Methods: 64 healthy male Wistar rats received different treatments such as: normal saline (NS), donepezil (Don), Scop and GSO, according to the previously designed protocol. Morris (MWM) was applied for spatial memory tests. Right after the behaviora

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45

Lee, Unji, Young H. Choi, So H. Kim, and Byung K. Lee. "Pharmacokinetics of Itraconazole in Diabetic Rats." Antimicrobial Agents and Chemotherapy 54, no. 2 (December 7, 2009): 931–33. http://dx.doi.org/10.1128/aac.01145-09.

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ABSTRACT After intravenous or oral administration of 10 mg/kg itraconazole to rats with streptozotocin-induced diabetes mellitus and to control rats, the total area under the plasma concentration-time curve from time 0 to 24 h (AUC0-24) for itraconazole and that for its metabolite, 7-hydroxyitraconazole, were similar between the two groups of rats. This may be explained by the comparable hepatic and intestinal intrinsic clearance rates for the disappearance of itraconazole and the formation of 7-hydroxyitraconazole in both groups of rats.

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46

Lister, P. D., M. J. Gentry, and L. C. Preheim. "Granulocyte Colony-Stimulating Factor Protects Control Rats but Not Ethanol-Fed Rats from Fatal Pneumococcal Pneumonia." Journal of Infectious Diseases 168, no. 4 (October 1, 1993): 922–26. http://dx.doi.org/10.1093/infdis/168.4.922.

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47

TORRES, Argenis, Diego F. DÁVILA, Carlos F. GOTTBERG, Jose H. DONIS, Gabriela ARATA DE BELLABARBA, and Paolo RAMONI-PERAZZI. "Heart rate responses to a muscarinic agonist in rats with experimentally induced acute and subacute chagasic myocarditis." Revista do Instituto de Medicina Tropical de São Paulo 42, no. 4 (August 2000): 219–24. http://dx.doi.org/10.1590/s0036-46652000000400007.

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We administered arecoline to rats, with experimentally induced chagasic myocarditis, in order to study the sinus node sensitivity to a muscarinic agonist. Sixteen month old rats were inoculated with 200,000 T. cruzi parasites ("Y" strain). Between days 18 and 21 (acute stage), 8 infected rats and 8 age-matched controls received intravenous arecoline as a bolus injection at the following doses: 5.0, 10.0, 20.0, 40.0, and 80.0 mug/kg. Heart rate was recorded before, during and after each dose of arecoline. The remaining 8 infected animals and 8 controls were subjected to the same experimental pr

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48

Liu, Zhaoheng, Wei Wang, Fang Cao, Shuo Liu, Xinxin Zou, Guodong Li, Haojie Yang, and Yang Jiao. "Number 2 Feibi Recipe Reduces PM2.5-Induced Lung Injury in Rats." Evidence-Based Complementary and Alternative Medicine 2018 (2018): 1–10. http://dx.doi.org/10.1155/2018/3674145.

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Air pollution is the main cause of respiratory diseases. Fine particulates with the diameter below 2.5 μm can get into the alveoli and then enter the blood circulation through the lung tissue ventilation function and cause multiple systemic diseases especially the respiratory diseases. This study investigated the pathological mechanism of the lungs injury in rats induced by PM2.5 and the effect and mechanism of the Chinese herbal medicine number 2 Feibi Recipe (number 2 FBR) on lungs injury. In this experiment, Wistar rats were used. Lungs injury was induced by PM2.5. Number 2 FBR was used to

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49

Bereznyakova, A. I., and V. F. Cheremisina. "Acid-based state of blood and mixture folds in rats with parodontal diseases." Fiziolohichnyĭ zhurnal 64, no. 1 (February 20, 2018): 66–72. http://dx.doi.org/10.15407/fz64.01.066.

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50

ITOH, Tomoo, Yasufumi SAWADA, TsuHan LIN, Tatsuji IGA, and Manabu NANANO. "Kinetic analysis of phenytoin disposition in rats with experimental renal and hepatic diseases." Journal of Pharmacobio-Dynamics 11, no. 5 (1988): 289–308. http://dx.doi.org/10.1248/bpb1978.11.289.

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