Academic literature on the topic 'RBC destruction'

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Journal articles on the topic "RBC destruction"

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Alfrey, C. P., M. M. Udden, C. Leach-Huntoon, T. Driscoll, and M. H. Pickett. "Control of red blood cell mass in spaceflight." Journal of Applied Physiology 81, no. 1 (1996): 98–104. http://dx.doi.org/10.1152/jappl.1996.81.1.98.

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The effect of spaceflight on red blood cell mass (RBCM), plasma volume (PV), erythron iron turnover, serum erythropoietin, and red blood cell (RBC) production and survival and indexes were determined for six astronauts on two shuttle missions, 9 and 14 days in duration, respectively. PV decreased within the first day. RBCM decreased because of destruction of RBCs either newly released or scheduled to be released from the bone marrow. Older RBCs survived normally. On return to Earth, plasma volume increased, hemoglobin concentration and RBC count declined, and serum erythropoietin increased. We
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Chadebech, Philippe, Marc Michel, Daniel Janvier та ін. "IgA-mediated human autoimmune hemolytic anemia as a result of hemagglutination in the spleen, but independent of complement activation and FcαRI". Blood 116, № 20 (2010): 4141–47. http://dx.doi.org/10.1182/blood-2010-03-276162.

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Abstract Autoimmune hemolytic anemia (AIHA) due to warm-acting IgA autoantibodies is rare. We explored the pathogenic mechanisms underlying destruction of red blood cells (RBCs) in a patient with severe AIHA mediated exclusively by polymeric immunoglobulin A (pIgA) anti-Band 3 autoantibodies. The follow-up period was 17 months. RBCs were not destroyed by complement activation as no deposition of complement was observed on the patient's RBCs. pIgA eluted from the patient's RBCs did not induce RBC destruction through phagocytosis by monocytes or antibody–dependent cell–mediated cytotoxicity by n
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Wouters, Diana, Stephan Femke, Masja de Haas, et al. "C1-Inhibitor Rescues Red Blood Cells From Complement Mediated Destruction in Autoimmune Hemolytic Anemia." Blood 118, no. 21 (2011): 716. http://dx.doi.org/10.1182/blood.v118.21.716.716.

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Abstract Abstract 716 In autoimmune hemolytic anemia (AIHA) autoantibodies (auto-Ab's) to red blood cells (RBCs) may induce complement activation via the classical pathway of complement resulting in complement deposition on RBCs. RBCs coated with auto-Ab and/or complement (C3b) are removed by extravascular destruction in the spleen and liver. In a minority of cases complement activation proceeds until insertion of the membrane attack complex (MAC) resulting in intravascular hemolysis. The inflammatory response and the anoxia induced by hemolysis significantly contribute to the morbidity and fa
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Allhorn, Maria, Juana G. Briceño, Lucie Baudino, et al. "The IgG-specific endoglycosidase EndoS inhibits both cellular and complement-mediated autoimmune hemolysis." Blood 115, no. 24 (2010): 5080–88. http://dx.doi.org/10.1182/blood-2009-08-239020.

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Abstract EndoS from Streptococcus pyogenes is an immunomodulating enzyme that specifically hydrolyzes glycans from human immunoglobulin G and thereby affects antibody effector functions. Autoimmune hemolytic anemia is caused by antibody-mediated red blood cell (RBC) destruction and often resists treatment with corticosteroids that also cause frequent adverse effects. We show here that anti-RhD (anti-D) and rabbit anti–human-RBC antibodies (anti-RBC) mediated destruction of RBC, ie, phagocytosis, complement activation, and hemolysis in vitro and in vivo was inhibited by EndoS. Phagocytosis by m
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Angus, Brian J., Kesinee Chotivanich, Rachanee Udomsangpetch, and Nicholas J. White. "In Vivo Removal of Malaria Parasites From Red Blood Cells Without Their Destruction in Acute Falciparum Malaria." Blood 90, no. 5 (1997): 2037–40. http://dx.doi.org/10.1182/blood.v90.5.2037.

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Abstract During acute falciparum malaria infection, red blood cells (RBC) containing abundant ring-infected erythrocyte surface antigen (Pf 155 or RESA), but no intracellular parasites, are present in the circulation. These RESA-positive parasite negative RBC are not seen in parasite cultures in vitro. This indicates that in acute falciparum malaria there is active removal of intraerythrocytic parasites by a host mechanism in vivo (probably the spleen) without destruction of the parasitized RBC. This may explain the observed disparity between the drop in hematocrit and decrease in parasite cou
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Zidova, Zuzana, Daniel Garcia-Santos, Katarina Kapralova, et al. "Oxidative Stress and Increased Destruction of Red Blood Cells Contribute to the Pathophysiology of Anemia Caused By DMT1 Deficiency." Blood 124, no. 21 (2014): 4027. http://dx.doi.org/10.1182/blood.v124.21.4027.4027.

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Abstract Inactivating mutations in divalent metal transporter 1 (DMT1) are associated with a severe defect in erythroid iron utilization and cause moderate to severe hypochromic microcytic anemia in human patients and two rodent models. We have previously shown that DMT1 deficiency impairs erythroid differentiation, induces apoptosis of erythroid precursors and causes the suppression of colony-forming capacity of erythroid progenitors. Using in vitro cultures of fetal liver cells we were able to recapitulate this in vivo defect. We confirmed abnormal pattern of erythroid differentiation and in
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Ashikaga, Kohei, Marco Alfonso Perrone, Antonio Gianfelici, et al. "Reticulocyte Count and Exercise Performance in Elite Athletes: A Retrospective Study." Sports 13, no. 6 (2025): 169. https://doi.org/10.3390/sports13060169.

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Athletes engaged in dynamic sports experience a shortened red blood cell (RBC) lifespan and accelerated turnover due to RBC destruction. This accelerated RBC turnover might have a positive impact on exercise performance by increasing the number of young red blood cells with a high oxygen-carrying capacity. However, accelerated turnover might also be a result of intravascular haemolysis caused by RBC destruction during exercise, impairing RBC function and oxygen transport. Therefore, we aimed to evaluate the relationship between reticulocyte count as an indicator of short-term RBC profile chang
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Arias, Clemente Fernandez, and Cristina Fernandez Arias. "How do red blood cells know when to die?" Royal Society Open Science 4, no. 4 (2017): 160850. http://dx.doi.org/10.1098/rsos.160850.

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Human red blood cells (RBCs) are normally phagocytized by macrophages of splenic and hepatic sinusoids at 120 days of age. The destruction of RBCs is ultimately controlled by antagonist effects of phosphatidylserine (PS) and CD47 on the phagocytic activity of macrophages. In this work, we introduce a conceptual model that explains RBC lifespan as a consequence of the dynamics of these molecules. Specifically, we suggest that PS and CD47 define a molecular algorithm that sets the timing of RBC phagocytosis. We show that significant changes in RBC lifespan described in the literature can be expl
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Vercaemst, Leen. "Hemolysis in Cardiac Surgery Patients Undergoing Cardiopulmonary Bypass: A Review in Search of a Treatment Algorithm." Journal of ExtraCorporeal Technology 40, no. 4 (2008): 257–67. http://dx.doi.org/10.1051/ject/200840257.

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Hemolysis is a fact in all extracorporeal circuits, as shown in various studies by the increasing levels of plasma-free hemoglobin (PfHb) and decreasing levels of haptoglobin during and after cardiopulmonary bypass (CPB). Beside complete red blood cell (RBC) destruction or hemolysis, RBCs can also be damaged on a sublethal level, resulting in altered rheological properties. Increased levels of free RBC constituents together with an exhaust of their scavengers result in a variety of serious clinical sequela, such as increased systemic and pulmonary vascular resistance, altered coagulation profi
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Yazdanbakhsh, Karina, Stanley Kang, Daniel Tamasauskas, Dorothy Sung, and Andromachi Scaradavou. "Complement receptor 1 inhibitors for prevention of immune-mediated red cell destruction: potential use in transfusion therapy." Blood 101, no. 12 (2003): 5046–52. http://dx.doi.org/10.1182/blood-2002-10-3068.

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AbstractActivation of complement cascade via the antibody-mediated classical pathway can initiate red blood cell (RBC) destruction, causing transfusion reactions and hemolytic anemia. In the present study, we have assessed the ability of a human recombinant soluble form of complement receptor 1 (sCR1) to inhibit complement-mediated RBC destruction in vitro and in vivo. Using an in vitro alloimmune incompatibility model, sCR1 inhibited complement activation and prevented hemolysis. Following transfusion of human group O RBCs into mice lacking detectable pre-existing antibodies against the trans
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Dissertations / Theses on the topic "RBC destruction"

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Bach, H. T., H. T. Hunter, D. A. Summa, et al. "Non-destructive evaluation of RbCl and Rb targets in Sr-82 production." Helmholtz-Zentrum Dresden - Rossendorf, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:d120-qucosa-165870.

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Introduction Sr-82 is produced for PET cardiac imaging at the Isotope Production Facility (IPF) with 100-MeV proton beams. During irradiation, the target material (RbCl, Rb) and Inconel capsule are ex-posed for extended periods to intense radiation, thermally and mechanically induced stresses, and chemicals. The structural integrity of the Inconel capsules is of crucial importance to containing the target starting materials and produced Sr-82. Unexpected failure capsules severely affects the reliability of the isotope supply chain and increases in radioactive emission and wastes, maintenance c
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Books on the topic "RBC destruction"

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Steensma, David P. Benign Hematology. Oxford University Press, 2012. http://dx.doi.org/10.1093/med/9780199755691.003.0294.

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The major forms of benign hematologic conditions are anemia, neutropenia, transfusion reactions, Gaucher disease, and porphyria. Anemia is a sign of disease rather than a disease itself. Anemia results from 1 or more of 3 pathologic mechanisms: inadequate production of red blood cells (RBCs) by the bone marrow, blood loss, or premature destruction of RBCs. The major causes of neutropenia include hematologic neoplasm, metastatic neoplasm involving the marrow, irradiation, vitamin B12 deficiency and folate deficiency, drugs, infections, congenital or acquired primary disorders of hematopoiesis,
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Zydroń, Tymoteusz. Wpływ systemów korzeniowych wybranych gatunków drzew na przyrost wytrzymałości gruntu na ścinanie. Publishing House of the University of Agriculture in Krakow, 2019. http://dx.doi.org/10.15576/978-83-66602-46-5.

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The aim of the paper was to determine the influence of root systems of chosen tree species found in the Polish Flysch Carpathians on the increase of soil shear strength (root cohesion) in terms of slope stability. The paper's goal was achieved through comprehensive tests on root systems of eight relatively common in the Polish Flysch Carpathians tree species. The tests that were carried out included field work, laboratory work and analytical calculations. As part of the field work, the root area ratio (A IA) of the roots was determined using the method of profiling the walls of the trench at a
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Book chapters on the topic "RBC destruction"

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Neelmeijer, C., M. Mäder, W. Wagner, and H. P. Schramm. "Layered Artefacts: Non-destructive Characterization by PIXE and RBS." In Optical Technologies in the Humanities. Springer Berlin Heidelberg, 1997. http://dx.doi.org/10.1007/978-3-642-60872-8_11.

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Ruvalcaba, J. L., and G. Demortier. "Non-Destructive Analysis Of American Gold Jewellery Items By PIXE, RBS and PIGE." In Application of Particle and Laser Beams in Materials Technology. Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-015-8459-3_31.

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Pruthi, Rajiv K. "Hemostatic Disorders." In Mayo Clinic Internal Medicine Board Review. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190464868.003.0038.

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Anemia is a reduction in the mass of healthy circulating red blood cells (RBCs). It results from 1 of 3 mechanisms: 1) inadequate production of RBCs by the bone marrow (ie, marrow failure, intrinsic RBC synthetic defects, or lack of essential RBC components such as vitamins); 2) blood loss; or 3) premature destruction of RBCs (ie, hemolysis). Microcytic anemia indicates the presence of small RBCs (mean corpuscular volume <80 fL). The most common forms of anemia are microcytic.
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Needs, Malcolm. "Immune-Mediated Red Cell Destruction." In Transfusion and Transplantation Science. Oxford University Press, 2018. http://dx.doi.org/10.1093/hesc/9780198735731.003.0008.

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This chapter shows how and why red blood cells (RBCs) are destroyed in the body, in vivo, by antibodies. It first describes the difference between intravascular and extravascular haemolysis. The chapter then defines the role of antibodies and complement in red cell destruction. It outlines the clinical significance of red cell antibodies and the use of the direct antiglobulin test (DAT). The chapter then shifts to detail the causes of haemolytic transfusion reactions, and the types of autoimmune haemolytic anaemias and the problems associated with finding compatible blood. Finally, the chapter
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Goldberg S.I., Tsibulkin E.K., Makhanek A.O., and Meshalkin L.D. "Employment of Dr.Watson Type Systems (Dr.WTS) in medicine on the example of supporting decision making by a physician of the Regional Children Reanimation Consultative Centre." In Studies in Health Technology and Informatics. IOS Press, 1993. https://doi.org/10.3233/978-1-60750-854-0-153.

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A new class of computer intellectual systems for assisting high-skilled specialists is offered. Its destructive feature is an increased attention to stimulation methods of a specialist's intellectual activity. Characteristics of the class are demonstrated on the example of DINAR-2.2 system supporting decision making by the physician- reanimatologist on duty of the Regional Children Reanimation Consultative Centre (RCC).
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Candigliota, E., and S. Biondi. "Non destructive tests for existing R.C. structures assessment." In Tailor Made Concrete Structures. CRC Press, 2008. http://dx.doi.org/10.1201/9781439828410.ch168.

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Kumar, Aman, Jasvir Singh Rattan, Nishant Raj Kapoor, Ajay Kumar, and Rahul Kumar. "Structural Health Monitoring of Existing Reinforced Cement Concrete Buildings and Bridge Using Nondestructive Evaluation with Repair Methodology." In Advances and Technologies in Building Construction and Structural Analysis. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.101473.

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Sustainable development means the utilization of resources at a rate less than the rate at which they are renewing. In India infrastructure industry is growing rapidly due to globalization and raising awareness. In the present study, challenges faced by countries like India are to sustain the existing expectations with limited resources available. Reinforced Concrete (RC) structure may suffer several types of defects that may jeopardize their service life. This chapter deals with condition assessment and repair of RCC (G+3) building situated at Northern part of the country. There are various t
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O’Connor*, Jim E., Ray E. Wells*, Scott E. K. Bennett*, et al. "Arc versus river—The geology of the Columbia River Gorge." In Proterozoic Nuna to Pleistocene Megafloods: Sharing Geology of the Inland Northwest. Geological Society of America, 2024. http://dx.doi.org/10.1130/2024.0069(10)abs.

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ABSTRACT The Columbia River Gorge is the Columbia River’s long-held yet evolving passage through the volcanic arc of the Cascade Range. The globally unique setting of a continental-scale river bisecting an active volcanic arc at the leading edge of a major plate boundary creates a remarkable setting where dynamic volcanic and tectonic processes interact with diverse and energetic fluvial processes. This three-day field trip explores several elements of the gorge and its remarkable geologic history—cast here as a contest between regional tectonic and volcanic processes building and displacing l
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Conference papers on the topic "RBC destruction"

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Khan Rana, Ahmad Raza, J. Kyle Williams, and Graham Brigham. "Case Studies - Learnings from CUI Failures and Inspection Challenges." In CONFERENCE 2024. AMPP, 2024. https://doi.org/10.5006/c2024-21070.

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Abstract Corrosion under insulation (CUI) is a leading damage mechanism that affects the entire hydrocarbon sector, from production to oil refinery settings. Modern-day inspection programs for CUI management are prioritized based on the risk scores associated with assets. This study addresses the numerous field learning for CUI management from various standpoints. It discusses in detail the outlooks and pitfalls with various disciplines namely non-destructive examination (NDE), risk-based inspections (RBI), workmanship (i.e., insulation craft), field maintenance/ retrofitting as well as corros
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Hassanein, Amro, and Ahmed Elsharkawi. "Integrity Maintaining and Cost Saving Advanced CUI Detection Technique (PEC)." In MPWT 2019. NACE International, 2019. https://doi.org/10.5006/mpwt19-14242.

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Abstract Corrosion under insulation (CUI) is a major problem for petroleum and petrochemical process industries that affects the plant mechanical integrity and attacks assets. CUI can result in sudden and hazardous leaks (safety concern), and plant shutdowns with high losses of production (economical concern). Traditional detecting methods of CUI to cut a window in thermal insulation used to inspect visually, to measure the thickness, and then return thermal insulation back, giving high chance for water and moisture ingress, accelerating CUI, moreover big amount of scaffolding erection along w
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Zhao, Hang, Qinghua Deng, Wenting Huang, and Zhenping Feng. "Thermodynamic and Economic Analysis and Multi-Objective Optimization of Supercritical CO2 Brayton Cycles." In ASME Turbo Expo 2015: Turbine Technical Conference and Exposition. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/gt2015-42631.

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Supercritical CO2 Brayton cycles (SCO2BC) offer the potential of better economy and higher practicability due to their high power conversion efficiency, moderate turbine inlet temperature, compact size as compared with some traditional working fluids cycles. In this paper, the SCO2BC including the SCO2 single-recuperated Brayton cycle (RBC) and recompression recuperated Brayton cycle (RRBC) are considered, and flexible thermodynamic and economic modeling methodologies are presented. The influences of the key cycle parameters on thermodynamic performance of SCO2BC are studied, and the comparati
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Bussel, J. "FOR MODULATION AS A MEANS OF ELEVATING THE PLATELET COUNT IN ITP." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644761.

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ITP is an autoantibody-mediated disease which would logically be treated by decreasing the level of autoantibody. However, the most exciting developments in understanding the pathophysiology of the thrombocytopenia and its treatment involve a better understanding of the MPS FcR system and ways in which it can be modulated. This work has focussed on phagocytic paralysis or FcR blockade (FcRBl): the slowing of destruction of antibody-coated platelets despite the persistent presence of antibody on the surface of the platelet.Several areas have been explored in learning about the MPS system. Inves
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Largura, Luiz C., Mauro D. Araujo, and Arilson R. Silva. "Corrosion Under Insulation (CUI) – Risk Based Inspection, Non-Destructive Inspection and Fitness for Service API-579." In Offshore Technology Conference Brasil. OTC, 2023. http://dx.doi.org/10.4043/32833-ms.

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Abstract This paper presents a Risk-Based Inspection (RBI) analysis of a pressure vessel (distillation column type) with a "Fitness-for-Service" (FFS) assessment of the equipment according to API-579 level 3. The evaluation of the resistance and stability of equipment corroded by Corrosion Under Insulation (CUI) is considered when subjected to design loads. The Risk Based Inspection evaluation was performed according to API 581 3rd edition, using the latest version of the GIEnd-RBI specialized software. The analysis showed a high probability level for Corrosion Under Insulation, which represen
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Diaferio, Mariella, and Michele Vitti. "Non-Destructive Tests for the Assessment of R.C. Buildings." In 2021 48th Annual Review of Progress in Quantitative Nondestructive Evaluation. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/qnde2021-74922.

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Abstract During the recent decades, the use of non-destructive tests has reached greater attention due to its high versatility and the possibility of extending the investigations on a great number of points. On the other side, the existence of a wide building stock realized in reinforced concrete, which is reaching the end of its service life, has increased the research on the assessment of their safety level. In this field, one of the most important parameters for r.c. structure is the concrete compressive strength, which “classically” is evaluated by means of compression tests on drilled cor
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Souza, Jarlyson Brunno Costa, Franklin Daniel Inácio, Samira Luns Hatum de Almeida, Armando Lopes de Brito Filho, Adão Felipe dos Santos, and Rouverson Pereira da Silva. "Peanut yield estimation models using Machine Learning techniques and Google Earth Engine." In Congresso Brasileiro de Agroinformática. Sociedade Brasileira de Computação, 2023. http://dx.doi.org/10.5753/sbiagro.2023.26546.

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The estimation of the yield for the peanut crop can be performed by visual methods, traditional destructive methods, which are time consuming, laborious and with imprecise predictions. Thus, the objective was to use SR techniques and Artificial Neural Networks (ANN) in the development of an innovative method for yield prediction in the peanut crop. The experiments were conducted in the state of São Paulo in the 2021/2022 crop season, in 6 commercial farms in sandy and clayey areas. The RBF and MLP networks were able to estimate peanut yield with an accuracy below 1000 kg/ha. GNDVI was a better
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Grandemange, Jean-Marie. "Adaptation of RCC-M Design and Construction Rules to the Evolution of Projects Needs, Regulatory Evolutions and International Exchanges." In ASME 2009 Pressure Vessels and Piping Conference. ASMEDC, 2009. http://dx.doi.org/10.1115/pvp2009-78046.

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The design and construction rules for mechanical components of LWR nuclear islands (RCC-M) constantly evolve to reflect the needs of the industry with the objective to fulfill the regulatory demands. Each year, an addendum is thus prepared by Afcen. The December 2008 addendum includes in particular new grades for products procurement, evolutions on destructive and non destructive examination provisions, consideration of new editions of standards, improvements of text for an easier application. For a better consistency with regulatory demands, technical code requirements have been updated (pres
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Ancelet, Olivier, Thierry Lebarbe´, Sophie Dubiez-Le Goff, Dominique Bonne, and Odile Ge´lineau. "Material Report in Support to RCC-MRx Code 2010: Stainless Steel Parts and Products." In ASME 2011 Pressure Vessels and Piping Conference. ASMEDC, 2011. http://dx.doi.org/10.1115/pvp2011-57852.

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This paper presents the Material Report dedicated to stainless steels parts and products issued by AFCEN (Association Franc¸aise pour les re`gles de Conception et de Construction des Mate´riels des Chaudie`res Electro-Nucle´aires) in support to RCC-MRx 2010 Code. The RCC-MRx Code is the result of the merger of the RCC-MX 2008, developed in the context of the research reactor Jules Horowitz Reactor project, in the RCC-MR 2007, which set up rules applicable to the design of components operating at high temperature and to the Vacuum Vessel of ITER (a presentation of RCC-MRx 2010 Code is the subje
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Dyer, Phillip, Griffin Smith, and George Nelson. "Exergy Analysis of Photovoltaics Coupled With Electrochemical Energy Storage for Lunar Power Applications." In ASME 2022 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2022. http://dx.doi.org/10.1115/imece2022-96993.

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Abstract Any inhabited base on the moon would require significant resources and power. Due to the high cost of delivering materials to the lunar surface, care must be taken to optimize energy storage and delivery systems. An exergy-based analysis of power generation systems based on a photovoltaic (PV) array coupled with energy storage is conducted. Exergy destruction rates are calculated through quasi-steady state energy and exergy balances, while exergy efficiencies for systems and subsystems are also quantified. The power system configurations analyzed include a PV array coupled with lithiu
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