Academic literature on the topic 'RCM (Ring closing metathesis)'

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Dissertations / Theses on the topic "RCM (Ring closing metathesis)"

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Pavlyuk, Oksana M. "Synthesis of Nitrogen-Containing Heterocycles via Carbenoid Insertion/Ring-Closing Metathesis Sequence." Ohio University / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1303761092.

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Salvador, Mayra Beloti. "Estudos visando a elucidação estrutural de uma diidro-2H-piranona natural." [s.n.], 2007. http://repositorio.unicamp.br/jspui/handle/REPOSIP/249254.

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Orientador: Ronaldo Aloise Pilli<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Quimica<br>Made available in DSpace on 2018-08-10T13:11:39Z (GMT). No. of bitstreams: 1 Salvador_MayraBeloti_M.pdf: 2010457 bytes, checksum: 350e267c8a65621fe41d0da941852b62 (MD5) Previous issue date: 2007<br>Resumo: Esta dissertação de mestrado trata da síntese da Criptomoscatona D2, uma lactona isolada pelo grupo de pesquisa dos Profs. Cavalheiro e Yoshida a partir da Cryptocarya moschata, planta encontrada em território brasileiro, cujas configurações relativa e absoluta ainda não
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Kavitake, Santosh. "A synergy between well-defined homogeneous and heterogeneous catalysts : the case of Ring Opening - Ring Closing Metathesis of cyclooctene." Thesis, Lyon 1, 2011. http://www.theses.fr/2011LYO10211/document.

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Dans le cadre de la formation sélective d'oligomères cycliques à partir du cyclo-octène, des matériaux hybrides organiques-inorganiques mésostructurés bien-définis contenant les unités Ru-NHC dissymétriques le long des canaux poreux de leur matrice de silice ont été développés et caractérisés à un niveau moléculaire. Tous les systèmes obtenus ont montré des fortes activités et sélectivités en oligomères cycliques (dimères : 50% et trimères : 25%) en RO-RCM du cyclo-octène, contrairement aux complexes homogènes Ru-NHC analogues symétriques (G-II et GH-II), qui conduisent préférentiellement à la
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Finelli, Fernanda Gadini. "Sintese da macrolactona da migrastatina e analogo : sinteses e aplicações de novos substratos em reações de RCAM catalisadas por [Mo]." [s.n.], 2009. http://repositorio.unicamp.br/jspui/handle/REPOSIP/248483.

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Orientador: Luiz Carlos Dias<br>Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Quimica<br>Made available in DSpace on 2018-08-13T21:30:59Z (GMT). No. of bitstreams: 1 Finelli_FernandaGadini_D.pdf: 6560101 bytes, checksum: 5eb9e7f25248bb940dd29d8af3e505ed (MD5) Previous issue date: 2009<br>Resumo: O capítulo 1 relata as sínteses da macrolactona da migrastatina 11 e da macrolactona análoga 62a. A macrolactona da migrastatina é o composto que apresenta a maior atividade de inibição de migração de células tumorais in vitro dentre os compostos da família da migrastatina até ho
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Helmboldt, Hannes. "Studien zur Synthese von Jatrophan-Diterpenen." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2006. http://nbn-resolving.de/urn:nbn:de:swb:14-1149002173288-83354.

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Es wird die enantioselektive Synthese eines substituierten Cyclopentanfragmentes beschrieben, welches zur Synthese einer Vielzahl von Diterpenen aus Euphorbiaceae genutzt werden kann. Schlüsselschritt hierbei ist eine intramolekulare Carbonyl-En-Reaktion. In zwei verschiedenen Syntheseansätzen wurde versucht, dieses zu einem Jatrophan-Diterpen umzusetzen. Versuche hinsichtlich einer Nozaki-Hiyama-Kishi-Kupplung werden beschrieben. Im zweiten Ansatz, wurde über eine Ringschlussmetathese bzw. eine Relay-Ringschlussmetathese versucht entsprechende Jatrophane herzustellen. Dies gelang bei einem Su
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Aitken, Steven Geoffrey. "Design, synthesis and testing of β-strand mimics as protease inhibitors". Thesis, University of Canterbury. Chemistry, 2006. http://hdl.handle.net/10092/1984.

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Chapter 1 gives background information on proteases and discusses the concept of protease inhibition as a therapeutic strategy for humans. It introduces the key concept that conformation defines biological activity. It also outlines how proteases almost universally bind their substrate/inhibitors in an extended β-strand conformation. The use of calpain as a prototype protease for the testing of β-strand mimics synthesised later in the thesis is also discussed. Chapter 2 describes how molecular modeling was used to rationalise the structure based activity relationships (SAR) of known calpain in
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Coe, Samuel. "Phyllostictine A ring assembly via ring closing metathesis." Thesis, University of Warwick, 2014. http://wrap.warwick.ac.uk/67101/.

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This thesis describes work focused on the chemical synthesis and herbicidal activity of the natural product phyllostictine A, a molecule of unique structure and unknown mode of action. Chapter 1 serves to introduce the natural product and describe the known activity of the natural product. Furthermore, it discusses literature methods for the construction of a-methylene-b-lactams, a key component of phyllostictine A. Chapter 2 describes work towards the construction of the macrocyclic rings found in phyllostictine A. As a result a-methylene-b-lactams have been shown, for the first time, to part
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Salim, Sofia Saima. "Synthesis of sulfamides using ring closing diene metathesis and enyne metathesis." Thesis, University of Southampton, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.417402.

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Miles, Steven Malcolm. "Bio-active molecule synthesis incorporating ring-closing metathesis." Thesis, Imperial College London, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.406173.

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10

Barker, William D. "Photoannulation and ring closing metathesis of carbohydrate derivatives." Thesis, University of Leicester, 2000. http://hdl.handle.net/2381/30040.

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The 'chiron approach' is a well-recognised technique for converting carbohydrates and other naturally occurring compounds into new chiral target molecules. The success of this area of chemistry can be attributed to the vast array of novel methods for transforming carbohydrates that have been developed over the last 50 years. Chapter 1 describes some of the key discoveries and pioneers within the field of carbohydrate annulation. As part of the Jenkins groups' on-going studies into the development of new methods for carbohydrate annulation, we have demonstrated the ease in which simple carbohyd
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