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1

Martin, Wehling, ed. Genomic and non-genomic effects of aldosterone. CRC Press, 1995.

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2

1929-, Shigeta Yukio, Kobayashi Masashi Dr, and Olefsky Jerrold M, eds. Recent advances in insulin action and its disorders: Proceedings of the International Symposium on Insulin Action and Its Disorders, Shiga, 16 May 1990. Excerpta Medica, 1991.

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3

Al-Hussary, Nabeel Ahmad Jargees. Insulin receptor binding in hypertension and non-insulin dependent diabetes mellitus. Aston University. Department of Molecular Sciences, 1986.

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4

1951-, Marescaux C., Vergnes M. 1935-, and Bernasconi R. 1929-, eds. Generalized non convulsive epilepsy: Focus on GABA-B receptors. Springer-Verlag, 1992.

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5

Marescaux, C., M. Vergnes, and R. Bernasconi, eds. Generalized Non-Convulsive Epilepsy: Focus on GABA-B Receptors. Springer Vienna, 1992. http://dx.doi.org/10.1007/978-3-7091-9206-1.

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6

Cushen, Arthur T., Ashok Nallawalla, and Bryan D. Clark. Better Radio/TV Reception: A Non-Technical Approach. Ashley Publishing, 1986.

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7

Rossetti, Carlo, and Francesco Peri, eds. The Role of Toll-Like Receptor 4 in Infectious and Non Infectious Inflammation. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-56319-6.

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8

1950-, Chaudhuri Sukanta, and Lim Chee Seng, eds. Shakespeare without English: The reception of Shakespeare in non-anglophone countries. Pearson Education, 2006.

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9

G, Burger H., ed. Inhibin-non-steroidal regulation of follicle stimulating hormone secretion. Raven Press, 1987.

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10

Pharand, Chantal. The use of platelet glycoprotein IIB/IIIA receptor antagonists in the management of unstable angina and non-st-elevation myocardial infarction: A critical evaluation. s.n., 2000.

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11

Wessels, Antonie. Images of Jesus: How Jesus is perceived and portrayed in non-European cultures. W.B. Eerdmans Pub. Co., 1990.

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12

Curtis, Anthony R. The outer space frequency directory: The radio monitor's guide to eavesdropping on satellites, space shuttles, space stations, interplanetary space probes, and non-human signals arriving at Earth from deep space. Tiare Publications, 1994.

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13

Kaar, Stephen J., Steven Potkin, and Oliver Howes. The neurobiology of antipsychotic treatment response and resistance. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198828761.003.0005.

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Dopamine D2/3 receptor occupancy by antipsychotic drugs is central to clinical response and many of their side effects. Yet the locus of dopaminergic alterations in the majority of patients with schizophrenia is not the D2/3 receptor but, instead, presynaptic, comprising elevated striatal dopamine synthesis and release capacity. However, whilst this explains why dopamine D2/3 receptor blockade is effective in many patients, a proportion of patients does not respond. In some this is because of inadequate antipsychotic blockade of dopamine receptors, but there are others who do not respond to an
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14

Desroches, Julie. Peripheral analgesia involves cannabinoid receptors. Edited by Paul Farquhar-Smith, Pierre Beaulieu, and Sian Jagger. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198834359.003.0034.

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This landmark paper by Agarwal and colleagues was published in 2007, when the exact contribution of the activation of the cannabinoid type 1 receptor (CB1) receptors expressed on the peripheral terminals of nociceptors in pain modulation was still uncertain. At that time, while it was clearly demonstrated that the central nervous system (CNS) was involved in the antinociceptive effects induced by the activation of the CB1 receptor, many strains of mice in which the gene encoding the CB1 receptor was deleted by conditional mutagenesis were used to study the specific role of these receptors in p
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15

S. Y. W. Shiu (Editor) and S. F. Pang (Editor), eds. Receptor and Non-Receptor Mediated Actions of Melatonin: Selected Papers from the International Symposium Held in Hong Kong, China, November 6-8, 1999 (Biological Signals and Receptors, 3-4). Not Avail, 2000.

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16

Burton, Derek, and Margaret Burton. Perception and sensation. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780198785552.003.0012.

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Major features of tetrapod sensory structures are well developed in fish which also have lateral lines, and some have electroreceptors and possibly magnetoreceptors. Receptors may be categorized according to the type of stimulus to which they respond: photoreceptors, chemoreceptors, mechanoreceptors, temperature receptors and nociceptors. Adaptations to aquatic habitats are described for examples from each category. Each type of receptor has the capacity to transduce (transform) its specific sensory stimulus into receptor potentials which initiate or modulate activity in sensory neurons to the
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17

Lambert, David G. Mechanisms and determinants of anaesthetic drug action. Edited by Michel M. R. F. Struys. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199642045.003.0013.

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This chapter is broken into two main sections: a general description of the principles of ligand receptor interaction and a discussion of the main groups of ‘targets’; and explanation of some common pharmacological interactions in anaesthesia, critical care, and pain management. Agonists bind to and activate receptors while antagonists bind to receptors and block the effects of agonists. Antagonists can be competitive (most common) or non-competitive/irreversible. The main classes of drug target are enzymes, carriers, ion channels, and receptors with examples of anaesthetic relevance interacti
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18

Abood, Mary E., Nephi Stella, and Roger G. Sorensen. EndoCANNABINOIDS: Actions at Non-CB1/CB2 Cannabinoid Receptors. Springer London, Limited, 2012.

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19

Abood, Mary E., Roger G. Sorensen, and Nephi Stella. endoCANNABINOIDS: Actions at Non-CB1/CB2 Cannabinoid Receptors. Springer, 2012.

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20

Abood, Mary E., Nephi Stella, and Roger G. Sorensen. EndoCANNABINOIDS: Actions at Non-CB1/CB2 Cannabinoid Receptors. Springer New York, 2014.

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21

Marescaux, C., M. Vergnes, and R. Bernasconi. Generalized Non-Convulsive Epilepsy: Focus on GABA-B Receptors. Springer London, Limited, 2013.

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22

Marescaux, C., M. Vergnes, and R. Bernasconi. Generalized Non-Convulsive Epilepsy: Focus on GABA-B Receptors. Springer, 2012.

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23

Vincent, Angela. Neuroimmunology. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199658602.003.0015.

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This chapter relates to antibody-mediated disorders throughout the nervous system. Early papers recall how use of bungarotoxin, passive transfer experiments in mice, and clinical response to plasma exchange confirmed the role of acetylcholine receptor antibodies in myasthenia gravis. Cutting edge techniques subsequently discovered other key neuromuscular junctional proteins, including muscle-specific kinase an additional target for antibodies. Later papers report the link between brain inflammation and severe amnesia, paraneoplastic and non-paraneoplastic, and the identification of the first p
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24

Rossetti, Carlo, and Francesco Peri. Role of Toll-Like Receptor 4 in Infectious and Non Infectious Inflammation. Springer International Publishing AG, 2021.

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25

Rossetti, Carlo, and Francesco Peri. Role of Toll-Like Receptor 4 in Infectious and Non Infectious Inflammation. Springer International Publishing AG, 2020.

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26

Abood, Mary E., and Thomas Gamage. The cloning and characterization of the cannabinoid type 1 receptor. Edited by Paul Farquhar-Smith, Pierre Beaulieu, and Sian Jagger. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198834359.003.0025.

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The cloning and characterization of the first cannabinoid receptor (now known as the cannabinoid type 1 (CB1) receptor) by Matsuda et al. in the landmark paper discussed in this chapter was a seminal discovery in 1990. While the analgesic properties of marijuana had been known for thousands of years, the mechanisms through which marijuana produces analgesia were not understood. The identification and functional characterization of the CB1 receptor led to the discovery of an endogenous cannabinoid system (the endocannabinoid system), which has now been shown to be important not only for acute a
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27

(Editor), C. Marescaux, M. Vergnes (Editor), and R. Bernasconi (Editor), eds. Generalized Non Convulsive Epilepsy: Focus on Gaba-B Receptors ("Journal of Neural Transmission"). Springer-Verlag, Austria, 1992.

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28

Crone, Patricia. The Iranian Reception of Islam: The Non-Traditionalist Strands. Edited by Hanna Siurua. BRILL, 2016. http://dx.doi.org/10.1163/9789004319295.

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29

Hohmann, Andrea G. Control of pain initiation by endogenous cannabinoids. Edited by Paul Farquhar-Smith, Pierre Beaulieu, and Sian Jagger. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198834359.003.0033.

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The landmark paper discussed in this chapter, published by Calignano et al. in 1998, focuses on the control of pain initiation by endogenous cannabinoids. In the paper, analgesic lipid mediators are shown to be present in peripheral paw tissue where they control the ability of pain signals to ascend to the central nervous system (CNS). Anandamide acts through a peripheral mechanism to suppress inflammatory pain via cannabinoid type 1 receptors. Palmitoylethanolamine, subsequently identified as an endogenous ligand for peroxisome proliferator-activated receptor-α‎, produces peripheral antinocic
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30

Mogil, Jeffrey S. Genetic differences in opiate receptors. Edited by Paul Farquhar-Smith, Pierre Beaulieu, and Sian Jagger. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198834359.003.0010.

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The 1975 manuscript ‘Opioid receptors in mice: Genetic differences’ by Baran and colleagues was the first published paper to forward a hypothesis as to what might underlie mouse strain differences in opioid analgesic response. A strain was identified, CXBK, that exhibited both deficient morphine analgesia and low μ‎-opioid receptor density. Further study of this strain over the next two decades proved very useful, and the phenotype of CXBK mice has now been explained at the molecular level. The Baran et al. paper presaged the modern genetic studies of the μ‎-opioid gene, OPRM1, and was an impo
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31

Hawes, Alison. Fish Facts. Pearson Education, 2004.

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32

Dahl, Vegard, and Ulrich J. Spreng. Anaesthesia for non-obstetric surgery. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198713333.003.0010.

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Anaesthesia for non-obstetric reasons is performed in 1–2% of all pregnant women. Although the chances of complications like miscarriage, preterm labour, and abortion are higher when surgery is performed during gestation, careful evaluation, preparation, and a multidisciplinary approach will minimize these risks. There are no methods of anaesthesia that are preferable to others during pregnancy. The most important preventive measure is to maintain maternal haemodynamic stability and normoventilation in order to ensure fetal well-being. Extensive knowledge of the profound anatomical and physiol
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33

Henter, Ioline D., and Rodrigo Machado-Vieira. Novel therapeutic targets for bipolar disorder. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198748625.003.0030.

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The long-term course of bipolar disorder (BD) comprises recurrent depressive episodes and persistent residual symptoms for which standard therapeutic options are scarce and often ineffective. Glutamate is the major excitatory neurotransmitter in the central nervous system, and glutamate and its cognate receptors have consistently been implicated in the pathophysiology of mood disorders and in the development of novel therapeutics for these disorders. Since the rapid and robust antidepressant effects of the N-methyl-D-aspartate (NMDA) antagonist ketamine were first observed in 2000, other NMDA
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34

De Backer, Daniel, and Patrick Biston. Vasopressors in critical illness. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0034.

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Vasopressors are used in various shock states to correct hypotension, aiming at restoring or improving organ and tissue perfusion. Vasopressor therapy may be associated with excessive vasoconstriction, but also metabolic and other side-effects. Hence, the ideal target for arterial pressure remains undetermined. Adrenergic agents remain the most commonly used vasopressor agents. Adrenergic agents increase arterial pressure through stimulation of alpha-adrenergic receptors. The effects of the different adrenergic agents differ mostly due to variable associated beta-adrenergic effects. Epinephrin
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35

Loader, Sarah. Bug Club Phonics Non-Fiction Reception Phase 4 Unit 12 Drums. Pearson Education, Limited, 2021.

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36

Varios. Rigby Star Independent Reception Pink Level Non Fiction Fish Colours Single. Rigby Educational Publishers, 2004.

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37

Varios. Rigby Star Independent Reception Pink Non Fiction Big and Little Single. Rigby Educational Publishers, 2004.

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38

Hume, Robert D. Authorship, Publication, Reception (2). Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780199580033.003.0002.

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This chapter examines the period between the mid-1680s and 1740, long considered to be the time ‘the rise of the novel’ occurred. Scholars have difficulty separating fiction from factual narrative during this era, as the authors and readers of the time thought of fiction not as the ‘novel’ but rather as a congeries of disparate and overlapping types: ‘history’, ‘letters’, ‘tale’, ‘romance’, ‘secret history’, ‘memoirs’, ‘true relation’, and the like. Only in the 1740s could one find a publishing environment more familiar to modern observers. Moreover, a recurrent theme of this era is price, to
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39

Patisaul, Heather B., and Scott M. Belcher. Receptor and Enzyme Mechanisms as Targets for Endocrine Disruptors. Oxford University Press, 2017. http://dx.doi.org/10.1093/acprof:oso/9780199935734.003.0005.

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In this chapter, the current understanding of the mechanisms of endocrine disruption on the brain and nervous system are presented. Because the overwhelming majority of mechanistic studies on EDCs have focused on the actions mediated by nuclear hormone receptors, this mechanisms is described in detail. The chapter also discusses the classic transcriptional mechanisms of steroid action and the impact of EDCs on rapid signaling (non-genomic) mechanisms. It presents an overview of the enzymes and pathways involved in the biosynthesis of steroid hormones, which are critical to proper functioning o
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40

Marescaux, C., and M. Vergnes. Generalized Non Convulsive Epilepsy: Focus on Gaba-B Receptors (Journal of Neural Transmission Supplementum). Springer, 1992.

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41

Huss, Boaz. Zohar: Reception and Impact. Liverpool University Press, 2016. http://dx.doi.org/10.3828/liverpool/9781904113966.001.0001.

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From its first appearance, the Zohar has been one of the most sacred, authoritative, and influential books in Jewish culture. Many scholarly works have been dedicated to its mystical content, its literary style, and the question of its authorship. This book focuses on different issues: it examines the various ways in which the Zohar has been received by its readers and the impact it has had on Jewish culture, including the fluctuations in its status and value and the various cultural practices linked to these changes. This dynamic and multi-layered history throws important new light on many as
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42

Cassidy, Jim, Donald Bissett, Roy A. J. Spence OBE, Miranda Payne, Gareth Morris-Stiff, and Amen Sibtain. Colorectal cancer. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199689842.003.0015_update_001.

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Breast cancer reviews the epidemiology and aetiology of this malignancy, with particular attention to the genetics underlying familial breast cancer, its pathology along with its receptors, oestrogen receptor (ER), the growth factor receptor HER2, and epidermal growth factor receptor (EGFR), and the bearing these have on treatment and prognosis. The benefits of breast cancer screening in the population and families at higher risk are discussed. Presenting symptoms and signs are followed by investigation including examination, bilateral mammography, and core biopsy of suspicious lesions. Manage
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43

Patel, Darpini H., and Bhuvan P. Raval. A Role of Tec : A non Receptor Tyrosine Kinase as Apoptotic Regulator: Enzyme in Programmed Cell Death. LAP Lambert Academic Publishing, 2012.

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44

Red Giant: Reception - Fiction and Non-Fiction Big Book Pack (Red Giant). Rigby Educational Publishers, 2000.

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45

Sunshine Reception Non-fiction: My Cat: Guided Reading Pack (Literacy Edition: Sunshine). Heinemann Educational Books - Primary Division, 1998.

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46

Tennant, Jason P. Autoradiographic analysis of delta-opoid receptors in the brains of weaned and non-weaned rats. 1995.

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47

Reedijk, Michael. Interactions of the non-catalytic kinase insert of the colony stimulating factor-1 receptor with intracellular signalling proteins. 1993.

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48

Newlove, Elizabeth. Bug Club Phonics Non-Fiction Reception Phase 4 Unit 12 Maps and Us. Pearson Education, Limited, 2021.

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49

Sunshine Reception Non-fiction: the Eggshell Garden: Guided Reading Pack (Literacy Edition: Sunshine). Heinemann Educational Books - Primary Division, 1998.

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50

Newlove, Elizabeth. Bug Club Phonics Non-Fiction Reception Phase 4 Unit 12 Grans and Grandads. Pearson Education, Limited, 2021.

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