Relevant bibliographies by topics / Recombinant Salmonella vaccine

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  2. Dissertations / Theses
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Academic literature on the topic 'Recombinant Salmonella vaccine'

Author: Grafiati
Published: 4 June 2021
Last updated: 5 February 2022

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Journal articles on the topic "Recombinant Salmonella vaccine"

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Kraehenbuhl, J. P., I. Corthésy-Theulaz, and D. Nardelli-Haefliger. "Recombinant Salmonella as vaccine carriers." Research in Immunology 149, no. 1 (January 1998): 87–90. http://dx.doi.org/10.1016/s0923-2494(98)80054-0.

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Bradley, Mark P., Lyn A. Hinds, and Peter H. Bird. "A bait-delivered immunocontraceptive vaccine for the European red fox (Vulpes vulpes) by the year 2002?" Reproduction, Fertility and Development 9, no. 1 (1997): 111. http://dx.doi.org/10.1071/r96066.

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An orally-delivered immunocontraceptive vaccine is being developed for the control of fox populations. A number of genes (PH-20, LDH-C4, ZP3) encoding gamete proteins have been cloned, produced in recombinant expression systems and used in fertility trials to test the efficacy of these antigens. As the immunocontraceptive vaccine will be delivered in a bait, there is a requirement for a greater understanding of the immune responses of the reproductive mucosa in canids, and the assessment of the best vaccine delivery system that will evoke a mucosal antibody response. Several vaccine delivery s
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Husseiny, Mohamed I., and Michael Hensel. "Rapid Method for the Construction of Salmonella enterica Serovar Typhimurium Vaccine Carrier Strains." Infection and Immunity 73, no. 3 (March 2005): 1598–605. http://dx.doi.org/10.1128/iai.73.3.1598-1605.2005.

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ABSTRACT Salmonella enterica serovar Typhimurium is a versatile organism for the generation of live recombinant vaccines for mucosal immunization. Various strategies have been devised for the stable and efficient expression of heterologous antigens by attenuated S. enterica strains, but these methods often require complex manipulations. Use of phage λ Red recombinase has recently been devised for gene replacements in Escherichia coli and S. enterica after introduction of PCR products. Based on this method, we have developed an approach that allows the integration of recombinant expression cass
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Potera, Carol. "Phosphatase Makes Recombinant Salmonella Vaccine Vectors Safer." Microbe Magazine 6, no. 11 (January 1, 2011): 471–72. http://dx.doi.org/10.1128/microbe.6.471.1.

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Kang, Ho Young, Jay Srinivasan, and Roy Curtiss. "Immune Responses to Recombinant Pneumococcal PspA Antigen Delivered by Live Attenuated Salmonella enterica Serovar Typhimurium Vaccine." Infection and Immunity 70, no. 4 (April 2002): 1739–49. http://dx.doi.org/10.1128/iai.70.4.1739-1749.2002.

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ABSTRACT Attenuated Salmonella enterica serovar Typhimurium expressing recombinant antigens from other pathogens elicits primarily a Th1-type dominant immune response to both recombinant and Salmonella antigens. The immunogenicity and appropriate subcellular location of the recombinant antigen in the Salmonella vaccine strain may contribute to augmenting immune responses by facilitating adequate exposure of recombinant antigen to antigen-presenting cells for processing. To allow for secretion from gram-negative bacteria and overexpression of antigen, a DNA fragment encoding a highly antigenic
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Su, Huali, Qing Liu, Xiaoping Bian, Shifeng Wang, Roy Curtiss, and Qingke Kong. "Synthesis and delivery of Streptococcus pneumoniae capsular polysaccharides by recombinant attenuated Salmonella vaccines." Proceedings of the National Academy of Sciences 118, no. 2 (December 30, 2020): e2013350118. http://dx.doi.org/10.1073/pnas.2013350118.

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Streptococcus pneumoniae capsular polysaccharides (CPSs) are major determinants of bacterial pathogenicity. CPSs of different serotypes form the main components of the pneumococcal vaccines Pneumovax, Prevnar7, and Prevnar13, which substantially reduced the S. pneumoniae disease burden in developed countries. However, the laborious production processes of traditional polysaccharide-based vaccines have raised the cost of the vaccines and limited their impact in developing countries. The aim of this study is to develop a kind of low-cost live vaccine based on using the recombinant attenuated Sal
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Gunn, Bronwyn M., Soo-Young Wanda, Dana Burshell, Caihong Wang, and Roy Curtiss. "Construction of Recombinant Attenuated Salmonella enterica Serovar Typhimurium Vaccine Vector Strains for Safety in Newborn and Infant Mice." Clinical and Vaccine Immunology 17, no. 3 (March 2010): 354–62. http://dx.doi.org/10.1128/cvi.00412-09.

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ABSTRACT Recombinant bacterial vaccines must be safe, efficacious, and well tolerated, especially when administered to newborns and infants to prevent diseases of early childhood. Many means of attenuation have been shown to render vaccine strains susceptible to host defenses or unable to colonize lymphoid tissue effectively, thus decreasing their immunogenicity. We have constructed recombinant attenuated Salmonella vaccine strains that display high levels of attenuation while retaining the ability to induce high levels of immunogenicity and are well tolerated in high doses when administered t
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Cao, Y., Z. Wen, and D. Lu. "Construction of a recombinant oral vaccine against Salmonella typhi and Salmonella typhimurium." Infection and Immunity 60, no. 7 (1992): 2823–27. http://dx.doi.org/10.1128/iai.60.7.2823-2827.1992.

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Curtiss III, Roy, Wei Xin, Yuhua Li, Wei Kong, Soo-Young Wanda, Bronwyn Gunn, and Shifeng Wang. "New Technologies in Using Recombinant Attenuated Salmonella Vaccine Vectors." Critical Reviews™ in Immunology 30, no. 3 (2010): 255–70. http://dx.doi.org/10.1615/critrevimmunol.v30.i3.30.

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Wang, Shifeng, Qingke Kong, and Roy Curtiss. "New technologies in developing recombinant attenuated Salmonella vaccine vectors." Microbial Pathogenesis 58 (May 2013): 17–28. http://dx.doi.org/10.1016/j.micpath.2012.10.006.

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Dissertations / Theses on the topic "Recombinant Salmonella vaccine"

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Hand, Nicholas. "Development of a Recombinant Attenuated Salmonella Cancer Vaccine." Thesis, The George Washington University, 2017. http://pqdtopen.proquest.com/#viewpdf?dispub=10635177.

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<p>New treatments for neuroblastoma are desperately needed; high-risk neuroblastoma patients have a less than 50% five-year survival rate despite intensive treatment. The greatest impact on improving survival rates for cancer patients in recent years is the result of a number of immunotherapeutic approaches. A proportion of high-risk neuroblastoma patients undergo spontaneous regression, possibly mediated by the immune system, indicating the potential of immunotherapies targeting neuroblastoma-associated antigens. Recombinant attenuated Salmonella vaccines (RASV) are cost-effective and have s
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Breau, Cathy. "Development of an oral recombinant chancroid vaccine delivered by attenuated Salmonella typhimurium SL3261." Thesis, University of Ottawa (Canada), 2009. http://hdl.handle.net/10393/28079.

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Chancroid, a sexually transmitted genital ulcer disease caused by the Gram-negative bacterium Haemophilus ducreyi, facilitates the acquisition and transmission of H1V. An effective vaccine against chancroid has yet to be developed. We hypothesize that a Salmonella vector-based vaccine, expressing H. ducreyi antigens, could confer protective immunity in the rabbit model of H. ducreyi infection. The H. ducreyi outer membrane hemoglobin receptor HgbA has been shown to be a suitable vaccine candidate. HgbA was expressed from S. typhimurium SL3261 (pnirBhgbA) but not from the control strain, S. typ
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O’Meara, Kellie Marcella. "Evaluation of Recombinant Salmonella Expressing CD154 for Enhanced Immune Responses in Commercial Turkeys." The Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=osu1246567532.

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Kremer, Courtney J. "Evaluation of Recombinant Salmonella Expressing the Flagellar Protein FliC for Enhanced Immune Responses in Commercial Turkeys." The Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=osu1246568225.

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Silva, Maria Elizabeth. "Development of a Recombinant Attenuated Salmonella Vaccine System for Taenia Solium Cysticercosis in Pigs." Digital Archive @ GSU, 2010. http://digitalarchive.gsu.edu/biology_diss/81.

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Taenia solium is a cestode that has a two-hosts life cycle. The adult tapeworm causes an asymptomatic disease known as taeniasis whereas the larval stage causes a disease called cysticercosis. In humans, the most common localization for the larvae is the central nervous system where it produces the neurological disorder neurocysticerco-sis. Previous works by several research groups around the world have shown that T. so-lium is a potentially eradicable parasite. Control programs have included treatment of human and pig populations with antihelmintics in conjunction with health education and ar
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Łaniewski, Paweł, Chang-Ho Baek, Kenneth L. Roland, and Roy Curtiss. "Analysis of Spleen-Induced Fimbria Production in Recombinant Attenuated Salmonella enterica Serovar Typhimurium Vaccine Strains." AMER SOC MICROBIOLOGY, 2017. http://hdl.handle.net/10150/625743.

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Salmonella enterica serovar Typhimurium genome encodes 13 fimbrial operons. Most of the fimbriae encoded by these operons are not produced under laboratory conditions but are likely to be synthesized in vivo. We used an in vivo expression technology (IVET) strategy to identify four fimbrial operons, agf, saf, sti, and stc that are expressed in the spleen. When any three of these operons were deleted, the strain retained wild-type virulence. However, when all four operons were deleted, the resulting strain was completely attenuated, indicating that these four fimbriae play functionally redundan
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Holden, James Anthony, and jamesholden@netspace net au. "Vaccination Strategies for the Prevention of Swine Dysentery." RMIT University. Applied Sciences, 2006. http://adt.lib.rmit.edu.au/adt/public/adt-VIT20070112.122102.

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The SmpA outer membrane lipoprotein of B. hyodysenteriae has several characteristics that indicate the potential to protect against swine dysentery (SD). It localises to the outer membrane and antibodies directed against SmpA can prevent the growth of B. hyodysenteriae in vitro. There is some variation observed in the distribution and expression of the SmpA lipoprotein, suggesting that vaccination with SmpA may not provide protection against challenge with a heterologous B. hyodysenteriae strain. This study has characterised the variation at the smpA locus, and in the process has identified
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Sevil, Victoria. "Influence of oral boost immunizations with recombinant Salmonella vaccine strains on the antigen-specific CD8 T-cell induction." Diss., lmu, 2007. http://nbn-resolving.de/urn:nbn:de:bvb:19-72867.

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Franzin, Fernanda Maria 1981. "Construção e analise da imunogenicidade de uma linhagem atenuada de Salmonella enterica produtora do dominio M2 do antigeno MAEBL de Plasmodium yoelii." [s.n.], 2009. http://repositorio.unicamp.br/jspui/handle/REPOSIP/317036.

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Orientadores: Marcelo Brocchi, Fabio Trindade Maranhão Costa<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-08-14T03:58:59Z (GMT). No. of bitstreams: 1 Franzin_FernandaMaria_M.pdf: 1412458 bytes, checksum: 2fe89ebc9e03c37ffcc48000024a232d (MD5) Previous issue date: 2009<br>Resumo: A malária é uma doença tropical causada pelo parasita Plasmodium spp e é considerada um sério problema de saúde pública. São aproximadamente 500 milhões de casos anuais e mais de um milhão de mortes, especialmente na África e Ásia. No Brasil,
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Chin'ombe, Nyasha. "Recombinant Salmonella enterica serovar Typhimurium vaccine vector expressing green fluorescent protein as a model antigen or human immunodeficiency virus type 1 subtype C Gag." Doctoral thesis, University of Cape Town, 2007. http://hdl.handle.net/11427/2723.

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Book chapters on the topic "Recombinant Salmonella vaccine"

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Curtiss, Roy, Sandra M. Kelly, Paul A. Gulig, and Koji Nakayama. "Stable Recombinant Avirulent Salmonella Vaccine Strains." In Immunobiology of Proteins and Peptides V, 33–47. Boston, MA: Springer US, 1989. http://dx.doi.org/10.1007/978-1-4757-2046-4_4.

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Doggett, Teresa A., and Roy Curtiss. "Delivery of Antigens by Recombinant a Virulent Salmonella Strains." In Genetically Engineered Vaccines, 165–73. Boston, MA: Springer US, 1992. http://dx.doi.org/10.1007/978-1-4615-3410-5_18.

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Rachmawati, Hidajah, Raditya Weka Nugraheni, and Firasti A.N. Sumadi. "In-Silico Approach in the Development of Salmonella Epitope Vaccine." In Salmonella - a Challenge From Farm to Fork [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.96313.

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In the case of infection control, one of our primary concerns is typhoid fever. According to WHO, typhoid prevalence in Indonesia is highly endemic. There is also the problem with the low efficacy of the available vaccine to prevent the disease. Therefore, there is an urgent need to develop a highly effective typhoid vaccine. One of the phases in vaccine development is an exploratory phase, a research-intensive phase of the vaccine development process designed to identify natural or synthetic antigens that might help prevent or treat a disease through computer in silico prediction targets. The vaccines developed through epitope peptide are designed to be safer, more efficacious, and less expensive than traditional vaccines. A thorough understanding of the disease agent, particularly critical epitopes to induce the appropriate immunological reaction, is required to achieve these aims. Mapping epitope sequences or antigenic peptides from pathogenic proteins recognized by B cells and T cells is crucial for vaccine development. Once the epitopes were identified, the polypeptide production could be produced through protein recombinant technology. The polypeptide vaccine, in the end, could be delivered using a liposomal delivery system.
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Curtiss, R., S. B. Porter, M. Munson, S. A. Tinge, J. O. Hassan, C. Gentry-Weeks, and S. M. Kelly. "NONRECOMBINANT AND RECOMBINANT AVIRULENT SALMONELLA LIVE VACCINES FOR POULTRY." In Colonization Control of Human Bacterial Enteropathologens in Poultry, 169–98. Elsevier, 1991. http://dx.doi.org/10.1016/b978-0-12-104280-6.50026-5.

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