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1
Paran, Kian, and Narges Noori. "TUNING OF THE PROPAGATION MODEL ITU-R P.1546 RECOMMENDATION." Progress In Electromagnetics Research B 8 (2008): 243–55. http://dx.doi.org/10.2528/pierb08062201.
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Wang, Han, Wencai Du, and Xing Chen. "Evaluation of Radio over Sea Propagation Based ITU-R Recommendation P.1546-5." Journal of Communications 10, no. 4 (2015): 231–37. http://dx.doi.org/10.12720/jcm.10.4.231-237.
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Ostlin, E., H. Suzuki, and H. J. Zepernick. "Evaluation of the Propagation Model Recommendation ITU-R P.1546 for Mobile Services in Rural Australia." IEEE Transactions on Vehicular Technology 57, no. 1 (January 2008): 38–51. http://dx.doi.org/10.1109/tvt.2007.901902.
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Fraiha Lopes, Ramz L., Simone G. C. Fraiha, Herminio S. Gomes, Vinicius D. Lima, and Gervasio P. S. Cavalcante. "Application of Hybrid ARIMA and Artificial Neural Network Modelling for Electromagnetic Propagation: An Alternative to the Least Squares Method and ITU Recommendation P.1546-5 for Amazon Urbanized Cities." International Journal of Antennas and Propagation 2020 (March 18, 2020): 1–12. http://dx.doi.org/10.1155/2020/8494185.
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This study sets out an empirical hybrid autoregressive integrated moving average (ARIMA) and artificial neural network (ANN) model designed to estimate electromagnetic wave propagation in densely forested urban areas. Received signal power intensity data was acquired through measurement campaigns carried out in the Metropolitan Area of Belém (MAB), in the Brazilian Amazon. Comparisons were made between estimates from classical least squares (LS) fitting and ITU (International Telecommunication Union) recommendation P. 1546-5. The results indicate the model is, at least, 44% more precise than every ITU estimate and, in some situations, is at least 11% better than an LS estimate, depending on the respective values of the relative error (RE).
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He, Jialuan, Zirui Xing, Qiang Wang, Feihong Wu, and Fuyong Lu. "A Study on the Diffraction Correction Prediction of Electromagnetic Field Intensity Based on the Method of Estimating Aerial Access Network Signal." Wireless Communications and Mobile Computing 2021 (September 11, 2021): 1–13. http://dx.doi.org/10.1155/2021/8136833.
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Field strength is a typical indicator of air access network signals, and the prediction of field strength has important reference significance for the estimation of aerial access network signals. However, many factors affecting the field strength, such as path, terrain, sunshine, and climate, increase the computational complexity, which greatly increases the difficulty of establishing an accurate prediction system. After persistent research by researchers in recent years, the ITU-R P.1546 model has gradually become a point-to-surface forecasting method for ground services recommended by ITU for ground operations in the frequency range of 30 MHz~3000 MHz. In view of the characteristics of electromagnetic signal propagation in mountainous environment, the influence of diffraction is also considered in this paper. Based on more accurate scene information such as actual terrain, the prediction calculation of electromagnetic signal propagation in a mountainous environment is proposed by using the corrected ITU-R P.1546 model. In addition, the influence of the actual terrain is taken into account to correct the relevant parameters, and the predicted results are compared with the measured data. The results indicate that field strength prediction results of the ITU-R P.1546 model based on the diffraction effect correction proposed in this paper in specific physical areas have better performance than those of the traditional ITU-R P.1546 model. Among them, the determination coefficient between the measured data and the predicted results is 0.87, the average error is 5.097 dBμV/m, and the root mean square error is 6.6228 dBμV/m, which proves that the ITU-R P.1546 model based on the corrected model is effective in the prediction of electromagnetic field intensity in the actual mountainous environment.
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Rodrigues, Christian Fragoas, Lisandro Lovisolo, and Lucas Muratori. "On the Parameters of ITU-R P.1546 Propagation Model for Dual-Polarization Links." IEEE Transactions on Broadcasting 66, no. 1 (March 2020): 56–65. http://dx.doi.org/10.1109/tbc.2019.2909181.
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Lewicki, Fryderyk. "ZASTOSOWANIE METOD WG ZALECEŃ ITU-R P. 528 i P.1546 DO PREDYKCJI NATĘŻENIA POLA DLA SŁUŻB LOTNICZYCH." PRZEGLĄD TELEKOMUNIKACYJNY - WIADOMOŚCI TELEKOMUNIKACYJNE 1, no. 4 (April 5, 2015): 255–57. http://dx.doi.org/10.15199/59.2015.4.63.
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Pinto Mangones, Angel Dario, Nelson Alexander Pérez García, Juan Manuel Torres Tovio, Eduardo José Ramírez, Samir Oswaldo Castaño Rivera, Jaime Velez Zapata, John Dwiht Ferreira Rodríguez, and Leidy Marian Rujano Molina. "Rainfall rate and rain attenuation contour maps for preliminary “Simon Bolivar” satellite links planning in Venezuela." DYNA 86, no. 209 (April 1, 2019): 30–39. http://dx.doi.org/10.15446/dyna.v86n209.73774.
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Predicting precipitation rate and rainfall attenuation are key aspects in planning and dimensioning of wireless communications systems operating at frequencies above 10 GHz, such as satellite communication systems at Ku and Ka bands. In this paper, contour maps of rainfall rate and rain attenuation are developed for the first time in Venezuela, based on 1-min rain rate statistics obtained from measurements carried out in Venezuela over at least 30 years period with a higher integration time and using Rice-Holmberg model, refined Moupfouma-Martin model and Recommendation ITU-R P.837-7, for rain rate estimation and Recommendation ITU-R P.618-13, Ramachandran-Kumar model, Yeo-Lee-Ong model and Rakshit-Adhikari-Maitra model, for rain attenuation prediction in “Simon Bolivar” satellite links in Venezuela. The overall results of both types of maps represent a useful tool for preliminary planning of those links in the country, specifically, in Ku and Ka bands
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Suh, Kyoung-Whoan. "A Consideration for Field Strength Analysis Based on Rec. ITU-R P.1546 Applicable to ATV to DTV Conversion." Journal of Broadcast Engineering 16, no. 5 (September 30, 2011): 824–33. http://dx.doi.org/10.5909/jeb.2011.16.5.824.
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Weinmann, Frank, and Klaus Dostert. "Verification of background noise in the short wave frequency range according to recommendation ITU-R P.372." AEU - International Journal of Electronics and Communications 60, no. 3 (March 2006): 208–16. http://dx.doi.org/10.1016/j.aeue.2005.03.005.
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Santos, Tiago, and Gilberto Carrijo. "Analysis of UHF signal propagation in the city of Uberlândia, using the propagation model ITU-R P.1546, OkumuraHata and LogDistância." IEEE Latin America Transactions 17, no. 09 (September 2019): 1560–66. http://dx.doi.org/10.1109/tla.2019.8932346.
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Ojo, Joseph Sunday. "Rain Height Statistics Based on 0°C Isotherm Height Using TRMM Precipitation Data for Earth-Space Satellite Links in Nigeria." ISRN Atmospheric Sciences 2014 (March 23, 2014): 1–5. http://dx.doi.org/10.1155/2014/798289.
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In the prediction of attenuation due to precipitation related phenomena, the 0°C isotherm height plays a vital role. In this paper, 2 years of precipitation data obtained from the Tropical Rain Measuring Mission (TRMM) satellite had been analyzed to establish the distribution of rain height based on 0°C isotherm heights over six locations in Nigeria. Probability of exceedance of rain heights in each of the locations was compared between the two seasons in Nigeria. Rain heights distribution was also compared with the ITU-R P.839 recommendation. The overall results show seasonal, rainfall type’s dependence and overestimation of the rain height predicted by the ITU for Nigeria.
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Lin, Leke, Xiangming Chen, Ranran Hu, and Zhenwei Zhao. "The Refraction Correction of Elevation Angle for the Mean Annual Global Reference Atmosphere." International Journal of Antennas and Propagation 2020 (May 7, 2020): 1–7. http://dx.doi.org/10.1155/2020/2438515.
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In some frequency-sharing studies between fixed service and space radiocommunication services, including fixed-satellite, broadcasting-satellite, and space science services, it is necessary to estimate the apparent elevation angle of a space station, taking into account the atmospheric refraction. Recommendations ITU-R (International Telecommunication Union—Radiocommunication) P.834-9 and F.1333-1 detail similar methods regarding calculating the refraction correction for the elevation angle of the mean annual global reference atmosphere. Herein, both methods are approximated using the bending angle from the ground to the infinity height; this approach is most suitable for geosynchronous orbit satellites. In this paper, new methods for calculating the refraction correction for the elevation angle are proposed regarding the mean annual global reference atmosphere given in Recommendation ITU-R P.835-6. Specifically, the results of the ray-tracing method are fitted. The height of the new formulae is 100 km above sea level. For higher altitudes, correction methods are given based on free-space propagation. The proposed methods can be applied to the calculation of the refraction correction for the elevation of the mean annual global reference atmosphere for satellites at different orbital heights. Furthermore, these new methods compare favourably to the two ITU-R Recommendations.
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Jordane da Silva, Marielle, Dick Carrillo Melgarejo, Renata Lopes Rosa, and Demóstenes Zegarra Rodríguez. "Speech Quality Classifier Model based on DBN that Considers Atmospheric Phenomena." Journal of communications software and systems 16, no. 1 (March 30, 2020): 75–84. http://dx.doi.org/10.24138/jcomss.v16i1.1033.
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Current implementations of 5G networks consider higher frequency range of operation than previous telecommunication networks, and it is possible to offer higher data rates for different applications. On the other hand, atmospheric phenomena could have a more negative impact on the transmission quality. Thus, the study of the transmitted signal quality at high frequencies is relevant to guaranty the user ́s quality of experience. In this research, the recommendations ITU-R P.838-3 and ITU-R P.676-11 are implemented in a network scenario, which are methodologies to estimate the signal degradations originated by rainfall and atmospheric gases, respectively. Thus, speech signals are encoded by the AMR-WB codec, transmitted and the perceptual speech quality is evaluated using the algorithm described in ITU-T Rec. P.863, mostly known as POLQA. The novelty of this work is to propose a non-intrusive speech quality classifier that considers atmospheric phenomena. This classifier is based on Deep Belief Networks (DBN) that uses Support Vector Machine (SVM) with radial basis function kernel (RBF-SVM) as classifier, to identify five predefined speech quality classes. Experimental Results show that the proposed speech quality classifier reached an accuracy between 92% and 95% for each quality class overcoming the results obtained by the sole non-intrusive standard described in ITU-T Recommendation P.563. Furthermore, subjective tests are carried out to validate the proposed classifier performance, and it reached an accuracy of 94.8%.
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Alhilali, Manhal, Jafri Din, Michael Schönhuber, and Hong Yin Lam. "Estimation of Millimeter Wave Attenuation Due to Rain using 2D Video Distrometer Data in Malaysia." Indonesian Journal of Electrical Engineering and Computer Science 7, no. 1 (July 1, 2017): 164. http://dx.doi.org/10.11591/ijeecs.v7.i1.pp164-169.
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<p>The increasing use of millimeter wave frequency bands requires a good understanding of the atmospheric channel. In equatorial regions, rain plays the central role in the impairment of millimeter wave propagation. Using large amounts of precise data collected by a two-dimensional video distrometer in Malaysia, the rain-specific attenuation of both vertically and horizontally polarized waves at the 38 GHz frequency was computed by applying the T-matrix technique. Good agreement is observed between these computations and fitted power law models from neighboring areas, but the ITU-R Recommendation P.838-3 significantly underestimates the rain-specific attenuation. The importance of including raindrop axial ratio in the calculation is revealed by differences among the local fitted coefficients for the vertically polarized estimations. The power law fit is provided, and the measurement is verified.</p>
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Fraiha Lopes, Ramz L., Simone G. C. Fraiha, Vinicius D. Lima, Herminio S. Gomes, and Gervásio P. S. Cavalcante. "Hybrid ARIMA and Neural Network Modelling Applied to Telecommunications in Urban Environments in the Amazon Region." International Journal of Antennas and Propagation 2020 (February 24, 2020): 1–14. http://dx.doi.org/10.1155/2020/2671746.
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This study explores the use of a hybrid Autoregressive Integrated Moving Average (ARIMA) and Neural Network modelling for estimates of the electric field along vertical paths (buildings) close to Digital Television (DTV) transmitters. The work was carried out in Belém city, one of the most urbanized cities in the Brazilian Amazon and includes a case study of the application of this modelling within the subscenarios found in Belém. Its results were compared with the ITU recommendations P. 1546-5 and proved to be better in every subscenario analysed. In the worst case, the estimate of the model was approximately 65% better than that of the ITU. We also compared this modelling with a classic modelling technique: the Least Squares (LS) method. In most situations, the hybrid model achieved better results than the LS.
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Pinto M, Ángel Dario, José Rafael Uzcátegui, Nelson Alexander Pérez García, José L. Aguilar, and Pedro V. González Castellanos. "Performance of Recommendation ITU-R P.1812-3 Model in the Propagation Loss Prediction for Digital Terrestrial Television in Caracas (Venezuela) and Belem (Brazil)." Ingeniería y Desarrollo 34, no. 2 (July 1, 2016): 441–62. http://dx.doi.org/10.14482/inde.34.2.8001.
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Bouleanu, Iulian, and Vlad-Cosmin Vasile. "Software Define Radio System for HF Noise Measurements." International conference KNOWLEDGE-BASED ORGANIZATION 23, no. 3 (June 27, 2017): 18–23. http://dx.doi.org/10.1515/kbo-2017-0150.
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AbstractAccurate noise estimation in the HF band is a defining aspect in the evaluation of SNR for communication links. The reference document that specifies how different types of electromagnetic noise can be taken into account by radio communication system planners is the ITU-R Recommendation P.372.Meanwhile a series of studies have demonstrated that Gaussian noise in the HF band is not always valid because this band noise is strongly affected by atmospheric emission sources such as lightning impulse. This leads to the idea that a distribution suited to express the noise variance is the Bi-Kappa distribution. In addition, over the past decade, SDR devices and real-time spectrum analysers, which can be used to evaluate this noise, have registered explosive growth. This article indicates technical solutions and procedures used to estimate the noise level in the HF subband which can be used for Near Vertical Incidence Skywave (NVIS) communications and proposes a measurement system based on a SDR solution which meets these requirements.
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Jokhanan, Patricia Alfira, Koesmarijanto Koesmarijanto, and Hudiono Hudiono. "Studi Kasus Pengaruh Tower Seluler terhadap Penerimaan Siaran Televisi Daerah Padat Penduduk di Jalan Buring Dalam pada Kecamatan Klojen Kota Malang." Jurnal Jartel: Jurnal Jaringan Telekomunikasi 11, no. 2 (June 28, 2021): 61–66. http://dx.doi.org/10.33795/jartel.v11i2.96.
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Penelitian ini bertujuan untuk menganalisis pengaruh adanya tower seluler terhadap kualitas penerimaan siaran TV di daerah padat penduduk yang berada di Jalan Buring Dalam Kecamatan Klojen, Kota Malang. Dari hasil pengukuran nilai kuat medan secara Line of Sight dan With Obstacle akan diketahui nilai redaman yang terjadi akibat adanya obstacle dengan jenis seluler. Setelah dilakukan pengukuran, akan dibandingkan dengan hasil perhitungan. Hasil penelitian ini adalah analisa pengaruh dari obstacle dengan jenis tower seluler terhadap pensinyalan tv analog, dengan membandingkan hasil pengukuran dan perhitungan yang didapat dari perhitungan kuat medan yang diterima menggunakan perhitungan redaman berdasarkan Rekomendasi ITU-R P.1546-1 dengan metode Okumura Hata, dan teori difraksi knife edge. Kesimpulan, hasil pengukuran dengan adanya obstacle tower seluler diperoleh rata – rata selisih antara Line of Sight dan With Obstacle sebesar 2.6525 dB dengan jarak obstacle 15 m dari titik pengukuran, dan 4.548571 dB dengan jarak 40 m . Nilai estimasi redaman rata – rata yang dipengaruhi difraksi tower seluler dengan jarak obstacle 15 m dari titik pengukuran sebesar 41.1088 dB, dan dengan jarak 40 m sebesar 36.67143 dB.Nilai redaman tower seluler berdasarkan pengukuran untuk jarak 15 m dari obstacle didapatkan nilai sebesar 2.6525 dB dan untuk perhitungan sebesar 41.1088 dB Sedangkan nilai redaman tower seluler berdasarkan hasil pengukuran untuk jarak 40 m memiliki rata – rata sebesar 4.548571 dB dan untuk perhitungan sebesar 36.67143 dB.
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Han, Congzheng, Liang Feng, Juan Huo, Zhaoze Deng, Gaoyuan Zhang, Baofeng Ji, Yushu Zhou, Yongheng Bi, Shu Duan, and Renmin Yuan. "Characteristics of Rain-Induced Attenuation over Signal Links at Frequency Ranges of 25 and 38 GHz Observed in Beijing." Remote Sensing 13, no. 11 (May 31, 2021): 2156. http://dx.doi.org/10.3390/rs13112156.
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Wireless communication has become a very important part of our lives, and it is well known that meteorological factors affect the quality of communication links, especially at higher frequencies because the physical dimensions of raindrops, hail stones, and snowflakes are on a similar wavelength to the propagating radio frequency. Millimeter-waves are an important technology for fifth-generation cellular networks which are currently being deployed all over the world. Since atmospheric effects are challenging in millimeter-wave transmissions, in this paper, we conducted line-of-sight field measurements at 25 GHz and 38 GHz. We monitored the received signal during rainfall events and compared the theoretical attenuation and the recorded rain-induced attenuation. We also derived the rain-induced attenuation (A) and rainfall rate (R) relation for stratiform and convective rain, respectively, using local rain drop size distribution (DSD) information at our measurement site collected during the period of two years. Furthermore, opportunistic sensing of atmospheric phenomena using microwave or millimeter-wave communication links in commercial cellular networks has recently attracted more attention in meteorological research worldwide. The accuracy of calculating rainfall rates from microwave links highly depends on the retrieval model and values of coefficients in the model, i.e., a and b of the A-R relation model. Here, the coefficients a and b are estimated based on local DSD measurement, and the performance of the improved A-R model is evaluated using propagated signal power based on measurement data. Compared to the (a, b) coefficients in the International Telecommunication Union Recommendation (ITU-R) P.838 document, the derived coefficients achieved an improved rainfall rate estimation.
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Linga, Promota Haule, Hashim Uledi Iddi, and Mussa Kissaka. "Rain attenuation distribution for satellite microwave links application in Tanzania." Indonesian Journal of Electrical Engineering and Computer Science 17, no. 2 (February 1, 2020): 982. http://dx.doi.org/10.11591/ijeecs.v17.i2.pp982-987.
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<table width="741" border="1" cellspacing="0" cellpadding="0"><tbody><tr><td valign="top" width="484"><p>Rain rate and Rain Attenuation predictions are important in radio system operating at Ku and Ka bands as they affect telecommunication systems performance. To adequately estimate rain-induced attenuation and fading, the International Telecommunication Union (ITU) recommends use of rainfall data collected using 1-minute integration time. For Tanzania, no rainfall data with 1-minute integration time is available either through measurements or conversion from rainfall data with longer integration time. In this paper the rain attenuation is predicted for seven locations in the coastal area of Tanzania. The 1- minute rainfall rate is determined by Chebil’s model using long-term measurements from Tanzania Metrological Agency (TMA) collected for a period of forty years, results obtained are used to estimate rain attenuations. By using the International Telecommunication Union-Recommendation (ITU-R) model, rain attenuation is predicted at horizontal polarization at Ku and Ka band. The results show that Unguja has the highest average annual rainfall accumulation with rain attenuation as high as ~53.22dB for Ka band and ~15.14dB for Ku band making the difference of about 38.08 between the two frequency bands. On the other hand, Kibaha which has the lowest average annual rainfall accumulation along the coast has rain attenuation of ~47.27dB for Ka and ~13.41dB for Ku bands, making the difference of 33.86dB between the frequency bands. Results obtained from this study can be useful in designing earth-satellite microwave links in the coastal area of Tanzania.</p></td></tr></tbody></table>
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Tsugawa, Takuya, Michi Nishioka, Mamoru Ishii, Kornyanat Hozumi, Susumu Saito, Atsuki Shinbori, Yuichi Otsuka, et al. "Total Electron Content Observations by Dense Regional and Worldwide International Networks of GNSS." Journal of Disaster Research 13, no. 3 (June 1, 2018): 535–45. http://dx.doi.org/10.20965/jdr.2018.p0535.
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Two-dimensional ionospheric total electron content (TEC) maps have been derived from ground-based Global Navigation Satellite System (GNSS) receiver networks and applied to studies of various ionospheric disturbances since the mid-1990s. For the purpose of monitoring and researching ionospheric conditions and ionospheric space weather phenomena, we have developed TEC maps of areas over Japan using the dense GNSS network, GNSS Earth Observation NETwork (GEONET), which consists of about 1300 stations and is operated by the Geospatial Information Authority of Japan (GSI). Currently, we are providing high-resolution, two-dimensional maps of absolute TEC, detrended TEC, rate of TEC change index (ROTI), and loss-of-lock on GPS signal over Japan on a real-time basis. Such high-resolution TEC maps using dense GNSS receiver networks are one of the most effective ways to observe, on a scale of several 100 km to 1000 km, ionospheric variations caused by traveling ionospheric disturbances and/or equatorial plasma bubbles, which can degrade single-frequency and differential GNSS positioning/navigation. We have collected all the available GNSS receiver data in the world to expand the TEC observation area. Currently, however, dense GNSS receiver networks are available in only limited areas, such as Japan, North America, and Europe. To expand the two-dimensional TEC observation with high resolution, we have conducted the Dense Regional and Worldwide International GNSS TEC observation (DRAWING-TEC) project, which is engaged in three activities: (1) standardizing GNSS-TEC data, (2) developing a new high-resolution TEC mapping technique, and (3) sharing the standardized TEC data or the information of GNSS receiver network. We have developed a new standardized TEC format, GNSS-TEC EXchange (GTEX), which is included in the Formatted Tables of ITU-R SG 3 Databanks related to Recommendation ITU-R P.311. Sharing the GTEX TEC data would be easier than sharing the GPS/GNSS data among those in the international ionospheric researcher community. The DRAWING-TEC project would promote studies of medium-scale ionospheric variations and their effect on GNSS.
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Ancans, G., E. Stankevicius, V. Bobrovs, and G. Ivanovs. "Estimation of Electromagnetic Compatibility Between DVB-T/DVB-T2 and 4G/5G in the 700 MHz Band for Co-Channel Case." Latvian Journal of Physics and Technical Sciences 57, no. 5 (October 1, 2020): 30–38. http://dx.doi.org/10.2478/lpts-2020-0025.
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AbstractThe 694–790 MHz band (700 MHz) known also as the second digital dividend was allocated to the mobile radiocommunication service on a primary basis in Region 1 and identified to International Mobile Telecommunications by the World Radiocommunication Conference 2012 (WRC-12). The designation of mobile service in Europe and other countries of Region 1 in 700 MHz band was obtained after the World Radiocommunication Conference 2015 (WRC-15). Administrations of Region 1 will be able to plan and use these frequencies for mobile networks, including IMT. The goal of this study is to estimate the electromagnetic compatibility of Digital Video Broadcasting – Terrestrial (DVB-T/DVB-T2) and LTE (Long Term Evolution) technology operating both in 700 MHz band. The study assumes frequency division duplex (FDD) channel arrangement of 703–733 MHz (for uplink) and of 758–788 MHz (for downlink).The model contains two parts: a DVB-T/DVB-T2 system and LTE mobile broadband network. Co-channel scenario is considered in this paper, and possible impact of DVB-T/DVB-T2 on LTE base stations (receivers) is also investigated. The Monte Carlo simulations within SEAMCAT software and the Minimum Coupling Loss (MCL) method are used for interference investigation. The coordination trigger field strength value predetermined by GE06 Agreement is also used in this study. The Monte Carlo method presents more relaxed electromagnetic compatibility scenario in comparison with the MCL method. For SEAMCAT simulations, ITU-R P.1546-5 radio propagation model is used.The obtained results present the required minimum separation distance between DVB-T/DVB-T2 and LTE networks in the 694–790 MHz in order to provide the necessary performance of LTE mobile network.
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Lin, Yi, Inge Huybrechts, Stefanie Vandevijvere, Selin Bolca, Willem De Keyzer, Stephanie De Vriese, Anja Polet, et al. "Fibre intake among the Belgian population by sex–age and sex–education groups and its association with BMI and waist circumference." British Journal of Nutrition 105, no. 11 (March 29, 2011): 1692–703. http://dx.doi.org/10.1017/s0007114510005088.
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The objectives of the present study were to assess total dietary fibre intake and the main contributors to fibre intake in the Belgian population by sex–age and sex–education groups and to investigate its relationship with BMI and waist circumference (WC). The participants of the Belgian food consumption survey (2004) were randomly selected. Information about food intake was collected using two repeated, non-consecutive 24 h recall interviews. A total of 3083 individuals ( ≥ 15 years; 1546 men and 1537 women) completed both interviews. The main contributors to total fibre intake (17·8 g/d) were cereals and cereal products (34 %; 5·9 g/d), potatoes and other tubers (18·6 %; 3·3 g/d), fruits (14·7 %; 2·8 g/d) and vegetables (14·4 %; 2·6 g/d). Legume fibre intake was extremely low (0·672 %; 0·139 g/d). In all sex–age and sex–education groups, total fibre intake was below the recommendations of the Belgian Superior Health Council. Men (21 g/d) consumed significantly more fibre than women (17·3 g/d) (P < 0·001). Lower educated men and higher educated women reported the highest fibre intake. A significant inverse association was found between total fibre intake and WC (β = − 0·118, P < 0·001). Fruit-derived fibre was positively associated with WC (β = 0·731, P = 0·001). In summary, total fibre intake was inversely associated with WC, whereas fruit-derived fibre intake was positively associated with WC in the Belgian population.
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Delarue, R., N. Mounier, C. Haioun, B. Coiffier, C. Gisselbrecht, H. Ghesquieres, P. Lederlin, et al. "Safety of Prophylactic Use of Darbepoetin Alfa in Patients with Diffuse Large B-Cell Lymphoma (DLBCL) Treated with R-CHOP 14 or R-CHOP21: Preliminary Results of the LNH03-6B Randomized GELA Study." Blood 108, no. 11 (November 1, 2006): 2436. http://dx.doi.org/10.1182/blood.v108.11.2436.2436.
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Abstract Introduction: Whether erythropoietin (Epo) has an impact on survival of patients (pts) with malignancies is debated. Since Dec 2003, the GELA has conducted a prospective randomized study to evaluate the safety and efficacy of Darbepoetin alfa (DA) in elderly pts with DLBCL treated by immunochemotherapy. In 2005, new recommendations about the use of Epo for patients with chemotherapy induced anemia have been published. Following these recommendations, the protocol was temporarily stopped and a first safety analysis was performed. Here we report the preliminary results on the first 130 enrolled patients. Patients and methods: pts between 66 and 80 years old with DLBCL and aaIPI ≥1 have been enrolled from Dec 2003 to Aug 2005. Pts were firstly randomised between two regimens combining Rituximab and the classical CHOP (Coiffier and al. NEJM 2002) delivered every 2 (R-CHOP14) or 3 weeks (R-CHOP21) for 8 cycles and were subsequently randomised between an investigational arm with DA (Arm 1) given in order to maintain hemoglobin (Hb) level between 13 and 15 g/dL and a conventional arm (Arm 2) with usual treatment of chemotherapy induced anemia, including transfusions and Epo according to usual practices. G-CSF was given according to physicians’decision. Results: 63 pts were randomised in Arm 1 and 67 in Arm 2. Median age is 71 y (66 – 80). Patients’characteristics were similar between arms and the percentage of patients with aaIPI 2–3 is 59%. Mean Hb level at randomisation is 12.2 g/dL (7.1 – 15.6). There rate of deaths during the treatment period is similar between arms (8% and 10%) and mainly related to treatment toxicity or lymphoma progression. The number of serious adverse events of any cause is lower in Arm 1 (96 events) compared to Arm 2 (153 events). Grade 3–4 Hb toxicity is higher in Arm 2 (39% versus 22%, p = NS). 18/63 (29%) patients received red blood cells transfusions in Arm 1 compared to 37/67 (55%) in Arm 2 (p=0.01). The number of patients with at least one episode of febrile neutropenia is lower in Arm 1 as compared to in Arm 2 (23% vs 36%, p = NS). There is no increase of cardiac and vascular events (respectively 9% and 9% in Arm 1 compared to 8% and 10% in Arm 2). The median level of Hb in Arm 1 during treatment is 12.05 g/dL and 10.65 g/dL in Arm 2. Sixteen percent of patients in Arm 1 have had at least one episode of Hb > 15 g/dL during treatment compared to 5% in Arm 2. The rate of thromboembolic events is similar in these patients (2/10) and in those who never have reached this Hb level (7/53). One year after completion of treatment, overall survival (OS) of the entire population is estimated at 74% and event free survival (EFS) at 67%. OS (78% in Arm 1 versus 70% in Arm 2 at 1 year) and EFS (73% in Arm 1 versus 64% in Arm 2 at 1 year) are similar between the two arms. Conclusions: these preliminary results provide encouraging results about the safety of a prophylactic use of Darbepoetin alfa and support the continuation of accrual to draw definite conclusions about safety and also efficacy.
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Zaidi Touis, Laila, Juliane Bolbrinker, Thomas Günther Riemer, and Reinhold Kreutz. "Moderation of alcohol consumption as a recommendation in European hypertension management guidelines: a survey on awareness, screening and implementation among European physicians." BMJ Open 8, no. 10 (October 2018): e022026. http://dx.doi.org/10.1136/bmjopen-2018-022026.
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ObjectivesModeration of alcohol consumption is included as a class I, level of evidence A recommendation in the current European guidelines for the management of hypertension. We investigated its awareness and self-reported implementation among European physicians across different specialties and workplaces.Design and settingA cross-sectional survey study conducted in two annual German meetings (German Society of Cardiology and the German Society of Internal Medicine) and two annual European meetings (European Society of Hypertension and European Society Cardiology) in 2015.Participants1064 physicians attending the European meetings were interviewed including 52.1% cardiologists, 29.2% internists and 8.8% general practitioners.Main outcome measuresPhysician screening of alcohol consumption, awareness and self-implementation of the recommendation of the current European guidelines about moderation of alcohol consumption for the management of hypertension.ResultsOverall, 81.9% of physicians reported to generally quantify alcohol consumption in patients with hypertension. However, only 28.6% and 14.5% of participants reported screening alcohol consumption in their patients with newly detected or treatment-resistant hypertension. Physicians recommended a maximum alcohol intake of 13.1±11.7 g/day for women (95% CI 12.3 to 13.8) and 19.9±15.6 g/day for men (95% CI 18.8 to 20.9). In case of moderate to high alcohol consumption, 10.3% would manage only hypertension without addressing alcohol consumption, while 3.7% of the physicians would do so in case of alcohol dependence (p<0.001).ConclusionsThe average amount of alcohol intake per day recommended by European physicians in this survey was in agreement with the guidelines. The low number of physicians that screen for alcohol consumption in patients with newly detected and with treatment-resistant hypertension indicates an important deficit in the management of hypertension.
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Galas, Noemi, Ingrid Becker, Tomasz Ficon, Maik Sakrauski, Rita Reichert, Wael Ahmad, Spyridon Mylonas, Jan Brunkwall, and Payman Majd. "Prescription rate of anti-atherosclerotic drugs in German nursing homes and its impact on outcome." Vasa 48, no. 2 (March 1, 2019): 158–66. http://dx.doi.org/10.1024/0301-1526/a000754.
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Abstract. Background: Peripheral arterial disease (PAD) is one of the major manifestations of general atherosclerosis and strongly associated with increased cardiovascular morbidity and mortality. Because only few epidemiologic studies are available concerning the prevalence of PAD in inhabitants ≥ 80 years of age, we screened inhabitants of nursing care homes in Germany for PAD and cardiovascular diseases and to assess the one year mortality. Patients and methods: We conducted a prospective cohort study, screening inhabitants of 42 nursing homes for PAD. Demographic data, comorbidities, cardiovascular risk factors and daily medication were collected. PAD was defined as ankle-brachial index < 0.9. During a follow up period of one year, cardio- and cerebrovascular events and mortality were recorded, as well as the rate of falls and major amputation. Results: 1,329 probands (391 men, 938 women) > 60 years were eligible for further analysis. The mean age was 84.1 years (range 61–107 years) and the prevalence of PAD was 31.5 % . Media sclerosis was found in up to 17 %, and an existing diagnosis of PAD (in case of pathological ABI) and undertreatment was common. Probands with PAD were less likely to be treated according to guideline recommendations (antiplatelet therapy, beta blockers, statins) than probands with coronary artery disease (CAD). The overall one-year mortality was 19.8 % (n = 236), significantly higher than for a gender and age matched German population (p < 0.001). Conclusions: The current study shows a high prevalence of PAD in German nursing care homes. The one year mortality was not significantly different between probands with PAD and those with severe PAD (defined as an ABI of ≤ 0.5), whereas a media sclerosis was associated with an increased risk in probands with CAD in comparison to those without. Use of anti-diabetic agents and aspirin in monotherapy was associated with a reduced one-year mortality risk. Keywords: Peripheral arterial disease, nursing care homes, coronary artery disease
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Chernysh, A. V. "Regression models of individual cephalometric indicators used in the method of R. M. Ricketts." Biomedical and Biosocial Anthropology, no. 32 (September 20, 2018): 56–62. http://dx.doi.org/10.31393/bba32-2018-08.
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It is proved that in the analysis of lateral teleroentgenograms according to different methods distances and angles have their normative indices which differ for persons of different ethnic, gender and age belongings. Therefore, for a full use in the orthodontics R.M. Ricketts method, similar studies are needed in Ukraine. The purpose of the work – in young men and women with normal occlusion close to the orthognathic bite and harmonious face construct and analyze the regression models of teleroentgenographic indicators used in the method of R. M. Ricketts. Primary lateral teleroentgenograms of 38 young men (aged 17-21 years) and 55 young women (aged from 16 to 20 years) with normal occlusion close to orthognathic bite and harmonic face, obtained from the Veraviewepocs 3D device, Morita (Japan), taken from the bank data of research center of National Pirogov Memorial Medical University, Vinnytsya. Cephalometric measurements were performed according to the recommendations of R. M. Ricketts. All indicators were divided into three groups: 1 - metric characteristics of the skull, which usually do not change during surgical and orthodontic treatment; 2 – tooth-jaw indicators, the definition of which most often guided by performing orthodontic manipulations of patients in children and adolescents, as well as those with already formed bone skeleton when orthodontic surgery can change the width, length, angles and position of the bones of the upper and lower jaws; 3 - indicators that characterize the position of each individual tooth relative to each other, to the bony cranial structures and face profile. The regression models of individual teleroentgenographic indicators used in the R.M. Ricketts methodology are constructed using the “Statistica 6.0” licensing package. Constructed all 2 reliable models of the indicators included in the second group (distance Go-CF and Xi-Pm), depending on the indicators of the first group (in young men R2 = 0.884 and 0.928, and in young women - 0.735 and 0.719); as well as in young men, 7 out of 8 possible reliable models (R2 = from 0.568 to 0.887) of the indicators included in the third group (the magnitude of the distances 6u-6l, Overjet, Overbite, 6u-PTV, 1l-APog, 1u-APog and Xi-OcP ) depending on the indicators of the first and second groups; and only 5 models for young women (6u-PTV, 1l-APog, 1u-APog and Xi-OcP distances, and the magnitude of the Max1-APog angle). In the analysis of entering into the regression models of the relevant predictors, it was found that in young men, among the teleroentgenographic indicators of the first group included in the two models of the second group, is the distance P-PTV, and in young women the front length of the base of the skull N-CC and the back of the skull base Ar- Pt It was also found that among young men among the teleroentgenographic indicators of the first and second groups, which were included in the models of the third group, the most frequent is the value of the distance B-Pog (11.1%); while in young women - distance B-Pog (15.6%) and an angle DC-Xi-PM (9.4%).
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El Rhazi, K., I. Huybrechts, M. Mint Sidi Deoula, K. El Kinany, R. Bakkali, S. A. Ibrahimi, and C. Nejjari. "Behavioural, Nutritional and Genetic Risk Factors of Colorectal Cancers in Morocco: Protocol for a Multicentre Case-Control Study." Journal of Global Oncology 4, Supplement 2 (October 1, 2018): 197s. http://dx.doi.org/10.1200/jgo.18.79702.
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Background: Colorectal cancer (CRC) is the third most common cancer in men and the second in women worldwide and its risk factors are complex. Genetic and environmental factors are strongly involved including lifestyle and eating habits. In Morocco, the number of new CRC cases is increasing. In parallel, cancer risk factors and behaviors of the Moroccan population are changing due to profound societal and technical changes. Aim: To that end we designed a multicenter case control study that aimed to evaluate the relationship between dietary habits, physical activity, genetics factors and the risk of CRC in Moroccan population. Methods: This case control study was conducted between January 2009 and February 2017 in 5 major University Hospital Centers in Morocco (Fez, Rabat, Oujda, Casablanca and Marrakech). Cases were matched with controls by age (±5 years), sex and center. Participants completed a face-to-face questionnaire on sociodemographic data, lifestyle, family history of CRC and no steroidal anti-inflammatory drugs. In addition, participants completed a semiquantitative food-frequency questionnaire (FFQ) was developed to assess food intake in the Morocco population. Pathology tumor samples were collected for 200 cases. For genetic data analysis, DNAs were extracted by manually scraping tissue from unstained slides. To assess the strength of the association between characteristics and the risk of CRC, odds ratios (OR) with 95% confidence intervals were estimated by conditional regression models. All statistical analyses were done using SPSS v20. Results: In total, 3032 pairs (1516 cases and 1516 controls) were recruited. Excluded participants (case/control) were unspecified primitive cancer (7 pairs), participants with missing dietary data (26 pairs) and participants with the lowest and highest 1% of the distribution of the ratio between energy intake and energy requirement (30 pairs). All together, 2906 cases and controls were recruited during the study period. Both cases and controls did not differ significantly with respect to sex 50.7% were women and 49.3% were men ( P = 0.51), the center that recruited the most was Rabat, followed by Casablanca, Oujda, Fez, and finally Marrakech ( P = 1.00). For marital status, being married was most frequent for both cases and controls (76.3% vs 77.0%) ( P = 0.36), alcohol consumption was higher in cases than controls (2.4% vs 1.7%) ( P = 0.12). However, participants in the control group were significantly more moderately active (58.4% vs 52.1%) and more likely to be never smoker (83.8% vs 77.6%). Conclusion: This study is the first large one that has described the risk factors of CRC in Morocco and in North Africa. It gives for the first time results about these risk factors which are drawn directly from this target population. Preventive recommendations could, therefore, be reviewed and adapted to these populations accordingly.
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Da Silva, Matheus Sebastian, Eliana C. Miranda, Marcia Torresan Delamain, Gislaine Oliveira Duarte, Bruna R. Vergilio, Ana Beatriz Pascoal Lopes, Jessica CN Vianna, Carmino Antonio De Souza, Erich Vinicius De Paula, and Katia B. Pagnano. "B3a2 Transcript Is an Independent Factor for the Achievement of a Deep Molecular Response in Chronic Phase - Chronic Myeloid Leukemia Patients Treated with Imatinib in First-Line." Blood 132, Supplement 1 (November 29, 2018): 1749. http://dx.doi.org/10.1182/blood-2018-99-114036.
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Abstract Introduction: The achievement of a deep and sustained molecular response after treatment with tyrosine kinase inhibitors (TKI) is one of the requirements for therapy discontinuation in chronic myeloid leukemia (CML) patients. Objectives: This study aimed to evaluate the proportion of CML patients treated with imatinib in first-line that achieve MR4.5 (BCR-ABL transcripts ≤ 0.0032% in the international scale) after imatinib treatment and the predictive factors for this response. The secondary objectives were to evaluate the rate of MMR (PCR ≤0.1%), MR4.0 (PCR ≤ 0.01%), time to molecular responses, event-free survival, progression-free and overall survival. Patients and methods: This is a retrospective analysis of CP-CML patients treated in first-line with imatinib in a single center. Patients diagnosed after 2006 were managed according to the European Leukemia Net recommendations. All patients started CML imatinib within six months from diagnosis. The type of BCR-ABL1 transcript was determined by multiplex RT-PCR from cDNA synthesized from total leukocytes RNA at diagnosis. BCR-ABL transcripts by quantitative real-time polymerase chain reaction were assessed at baseline, and then every three months for the first year until reaching a stable major molecular response, then every 3-6 months. The SPSS software was used for the Cox Regression model for univariate and multivariate analysis, using backward Wald. The cumulative incidence was calculated with the R Program, with Gray test for curve comparisons. Event-free, progression-free and overall survivals were calculated with the Kaplan-Meier method, and the curves were compared with the log-rank test. Results: From January 2005 to December 2015 172 patients were treated with imatinib, median age 48 years (18-93), 55.8% male. Sokal score: 31% low-risk, 40% intermediate-risk and 29% high-risk. The median follow-up was 56 months (0-157). The Cumulative Incidence (CI) of MMR was 48% in 24 months and 84% in 5 years, while the CI of MR4.0 and MR4.5 was 63% and 51%, respectively, in 5 years. The median time to MMR, MR4.0 and MR4.5 was 16.7 (2-102), 31 (5-150) and 36 months (7-153), respectively. The univariate regression factors related to MR4.5 achievement were: age >48 years (HR 1.79; 95%CI: 1.08-2.98; P=0.023); days between diagnosis and imatinib start (HR=0.99; 95%CI: 0.98-0.99, P=0.020); e14a2 (b3a2) transcript (HR= 3.37; 95%CI: 1.67-6.81; P=0.001), which was the only factor in the multivariate analysis. Imatinib was discontinued in 96/172 (55.8%) patients due to resistance (36.5%), intolerance (20.8%), clinical trials (25%), death (15.6%) and adherence (2.1%). Eighteen out of 67 (26.8%) patients that achieved MR4.5 are currently participating in a discontinuation trial. Overall survival, PFS and EFS were 92%, 87% and 61% in 5 years. Conclusion: Approximately half of the patients that start imatinib in first-line obtain deep molecular responses within five years and could be candidates for treatment discontinuation. B3a2 transcript was an independent factor for MR4.5 achievement in the multivariate analysis, confirming the results of other studies that have reported earlier and deeper molecular responses in patients with b3a2 transcripts. Disclosures De Paula: Hematology and Transfusion Medicine Center, University of Campinas: Employment. Pagnano:Abbvie: Consultancy; EMS: Other: Financial support for participation in congress; Shire: Other: Lecture; Novartis: Consultancy.
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Nafee, Hoda Mohamed, Awatef El-Sayed Ahmed, and Ahlam Mohamed Hussien. "Objective structured clinical examination versus traditional clinical examination among nursing students: A comparative approach." Journal of Nursing Education and Practice 9, no. 2 (September 29, 2018): 42. http://dx.doi.org/10.5430/jnep.v9n2p42.
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The complex nature of clinical competence in nursing consequently poses a challenge in identifying suitable assessment methods that are able to measure all its attributes as well as maintaining reliability, validity and objectivity. So the aim of this study was to compare nursing students’ opinions, feedback and clinical achievements grades in the Objective Structured Clinical Examination (OSCE) and the Traditional Clinical Examination (TCE) methods. A descriptive research design was used to conduct the study at college of nursing –Immam Abdulrahman Bin Faisal University (IABU), kingdom of Saudi Arabia. A total of 96 undergraduate student nurses enrolled in the pediatric nursing course equally were divided randomly into TCE and OSCE group (n = 48) in each group. Two tools were used, first tool was a structured questionnaire form to collect data related student’s academic number, age, method of exam used, achievement grades in the exam and the overall suggestions to improve the method of exam used where the second tool was a self-administered questionnaire that modified from a Pierre et al. (2004) OSCE feedback questionnaire which included 23 items and categorized under four main dimensions with 3-point Likert scale ranged from agree, neutral and disagree to evaluate students’ opinions and feedback related to the quality, organization, scoring and physical set up of both methods. Results revealed that statistical significant differences were found with higher prevalence of agreement responses among students for OSCE methods related most of items listed in the four dimensions compared to those in TCE. Mean ± SD total score of students’ responses related to OSCE and TCE methods was 104.5 ± 15.6 and 95.3 ± 17.5 respectively where p value = .002. Majority of students 95.8% exposed to OSCE compared to 11.9% of them who exposed to the TCE achieved (A) excellent grades in the exam (score 90%-100%). Conclusion and recommendation, statistical significant differences were observed between students’ opinion and feedback with high prevalence of agreement responses related to OSCE compared to TCE methods. Clinical achievement grade was high among students whom evaluated by OSCE compared to those evaluated by TCE method. The study recommended that OSCE must be used as an integral part of the under graduate nursing students’ clinical assessment.
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Bath, Philip M., Lisa J. Woodhouse, Jason P. Appleton, Maia Beridze, Hanne Christensen, Robert A. Dineen, Katie Flaherty, et al. "Triple versus guideline antiplatelet therapy to prevent recurrence after acute ischaemic stroke or transient ischaemic attack: the TARDIS RCT." Health Technology Assessment 22, no. 48 (August 2018): 1–76. http://dx.doi.org/10.3310/hta22480.
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BackgroundTwo antiplatelet agents are better than one for preventing recurrent stroke after acute ischaemic stroke or transient ischaemic attack (TIA). Therefore, intensive treatment with three agents might be better still, providing it does not cause undue bleeding.ObjectiveTo compare the safety and efficacy of intensive therapy with guideline antiplatelet therapy for acute ischaemic stroke and TIA.DesignInternational prospective randomised open-label blinded end-point parallel-group superiority clinical trial.SettingAcute hospitals at 106 sites in four countries.ParticipantsPatients > 50 years of age with acute non-cardioembolic ischaemic stroke or TIA within 48 hours of ictus (stroke).InterventionsParticipants were allocated at random by computer to 1 month of intensive (combined aspirin, clopidogrel and dipyridamole) or guideline (combined aspirin and dipyridamole, or clopidogrel alone) antiplatelet agents, and followed for 90 days.Main outcome measuresThe primary outcome was the incidence and severity of any recurrent stroke (ischaemic, haemorrhagic; assessed using the modified Rankin Scale) or TIA within 90 days by blinded telephone follow-up. Analysis using ordinal logistic regression was by intention to treat. Other outcomes included bleeding and its severity, death, myocardial infarction (MI), disability, mood, cognition and quality of life.ResultsThe trial was stopped early on the recommendation of the Data Monitoring Committee after recruitment of 3096 participants (intensive,n = 1556; guideline,n = 1540) from 106 hospitals in four countries between April 2009 and March 2016. The incidence and severity of recurrent stroke or TIA did not differ between intensive and guideline therapy in 3070 (99.2%) participants with data [93 vs. 105 stroke/TIA events; adjusted common odds ratio 0.90, 95% confidence interval (CI) 0.67 to 1.20;p = 0.47]. Major (encompassing fatal) bleeding was increased with intensive as compared with guideline therapy [39 vs. 17 participants; adjusted hazard ratio (aHR) 2.23, 95% CI 1.25 to 3.96;p = 0.006]. There were no differences between the treatment groups in all-cause mortality, or the composite of death, stroke, MI and major bleeding (aHR 1.02, 95% CI 0.77 to 1.35;p = 0.88).LimitationsPatients and investigators were not blinded to treatment. The comparator group comprised two guideline strategies because of changes in national guidelines during the trial. The trial was stopped early, thereby reducing its statistical power.ConclusionsThe use of three antiplatelet agents is associated with increased bleeding without any significant reduction in recurrence of stroke or TIA.Future workThe safety and efficacy of dual antiplatelet therapy (combined aspirin and clopidogrel) versus aspirin remains to be defined. Further research is required on identifying individual patient response to antiplatelets, and the relationship between response and the subsequent risks of vascular recurrent events and bleeding complications.Trial registrationCurrent Controlled Trials ISRCTN47823388.FundingThis project was funded by the National Institute for Health Research (NIHR) Health Technology Assessment programme and will be published in full inHealth Technology Assessment; Vol. 22, No. 48. See the NIHR Journal Library website for further project information. The Triple Antiplatelets for Reducing Dependency after Ischaemic Stroke (TARDIS) vanguard phase was funded by the British Heart Foundation (grant PG/08/083/25779, from 1 April 2009 to 30 September 2012) and indirect funding was provided by the Stroke Association through its funding of the Stroke Trials Unit, Division of Clinical Neuroscience, University of Nottingham, Nottingham, UK. There was no commercial support for the trial and antiplatelet drugs were sourced locally at each site. The trial was sponsored by the University of Nottingham.
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Schlenk, Richard F., Walter Fiedler, Helmut R. Salih, Gerald Wulf, Felicitas Thol, Andrea Kündgen, Thomas Kindler, et al. "Impact of Age and Midostaurin-Dose on Response and Outcome in Acute Myeloid Leukemia with FLT3-ITD: Interim-Analyses of the AMLSG 16-10 Trial." Blood 128, no. 22 (December 2, 2016): 449. http://dx.doi.org/10.1182/blood.v128.22.449.449.
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Abstract Background: Internal tandem duplications (ITD) in the receptor tyrosine kinase FLT3 occur in roughly 25% of younger adult patients (pts) with acute myeloid leukemia (AML). The multi-targeted kinase inhibitor midostaurin combined with intensive chemotherapy has shown activity against AML with FLT3 mutations. However, toxicity and potential drug-drug interactions with strong CYP3A4 inhibitors such as posaconazole may necessitate dose reduction. Aims: To evaluate the impact of age and midostaurin dose-adaptation after intensive induction chemotherapy on response and outcome in AML with FLT3-ITD within the AMLSG 16-10 trial (NCT01477606). Methods: The study included adult pts (age 18-70 years (yrs)) with newly diagnosed FLT3-ITD positive AML enrolled in the ongoing single-arm phase-II AMLSG 16-10 trial. Pts with acute promyelocytic leukemia were not eligible. The presence of FLT3-ITD was analyzed within our diagnostic study AMLSG-BiO (NCT01252485) by Genescan-based DNA fragment-length analysis. Induction therapy consisted of daunorubicin (60 mg/m², d1-3) and cytarabine (200 mg/m², continuously, d1-7); midostaurin 50 mg bid was applied from day 8 until 48h before start of the next treatment cycle. A second cycle was allowed in case of partial remission (PR). For consolidation therapy, pts proceeded to allogeneic hematopoietic-cell transplantation (HCT) as first priority; if alloHCT was not feasible, pts received three cycles of age-adapted high-dose cytarabine (HDAC) in combination with midostaurin starting on day 6. In all pts one-year maintenance therapy with midostaurin was intended. The first patient entered the study in June 2012 and in April 2014, after recruitment of n=147 pts, the study was amended including a sample size increase to 284 pts and a dose reduction to 12.5% of the initial dose of midostaurin in case of co-medication with strong CYP3A4 inhibitors (e.g. posaconazole). This report focuses on age and the comparison between the first (n=147) and the second cohort (n=137) of the study in terms midostaurin dose-adaptation. Results: Patient characteristics were as follows: median age 54 yrs (range, 18-70; younger, 68% < 60 yrs; older, 32% ≥ 60 yrs); median white cell count 44.7G/l (range 1.1-1543 G/l); karyotype, n=161 normal, n=16 high-risk according to ELN recommendations; mutated NPM1 n=174 (59%). Data on response to first induction therapy were available in 277 pts; complete remission (CR) including CR with incomplete hematological recovery (CRi) 60%, PR 20%, refractory disease (RD) 15%, and death 5%. A second induction cycle was given in 54 pts. Overall response (CR/CRi) after induction therapy was 76% (76%, younger; 76%, older) and death 6% (4%, younger; 10% older). The dose of midostaurin during first induction therapy was reduced in 53% and 71% of patients in cohort-1 and cohort-2, respectively. Reasons for dose reduction were in 58% and 49% toxicity, and in 9% and 23% co-medication in cohort-1 and cohort-2, respectively. No difference in response to induction therapy was noted between cohorts (p=0.81). Median follow-up was 18 months. Overall 146 pts received an alloHCT, 128 in first CR (n=94 younger, n=34 older; n=92 from a matched unrelated and n=36 from a matched related donor). In pts receiving an alloHCT within the protocol in median two chemotherapy cycles were applied before transplant (range 1-4). The cumulative incidence of relapse (CIR) and death after transplant were 13% (SE 3.2%) and 16% (SE 3.5%) without differences (p=0.97, p=0.41, respectively) between younger and older patients. So far maintenance therapy was started in 86 pts, 61 pts after alloHCT and 25 pts after HDAC. Fifty-five adverse events 3°/4° were reported being attributed to midostaurin; cytopenias after alloHCT were the most frequent (29%). CIR in patients starting maintenance therapy was 20% one year after start of maintenance without difference between alloHCT and HiDAC (p=0.99). In addition, no difference in CIR was identified in patients after consolidation with alloHCT or HDAC according to dose reduction of midostaurin during first induction therapy (p=0.43, p=0.98, respectively). Median overall survival was 25 months (younger, 26 months; older 23 months; p=0.15). Conclusions: The addition of midostaurin to intensive induction therapy and as maintenance after alloHCT or HDAC is feasible and effective without an impact of age and dose adaptation on outcome. Disclosures Schlenk: Amgen: Research Funding; Pfizer: Honoraria, Research Funding. Fiedler:GSO: Other: Travel; Pfizer: Research Funding; Kolltan: Research Funding; Amgen: Consultancy, Other: Travel, Patents & Royalties, Research Funding; Gilead: Other: Travel; Ariad/Incyte: Consultancy; Novartis: Consultancy; Teva: Other: Travel. Lübbert:Celgene: Other: Travel Funding; Janssen-Cilag: Other: Travel Funding, Research Funding; Ratiopharm: Other: Study drug valproic acid. Greil:Janssen-Cilag: Honoraria; Genentech: Honoraria, Research Funding; Mundipharma: Honoraria, Research Funding; Merck: Honoraria; AstraZeneca: Honoraria; Boehringer-Ingelheim: Honoraria; GSK: Research Funding; Ratiopharm: Research Funding; Cephalon: Consultancy, Honoraria, Research Funding; Celgene: Consultancy, Honoraria, Research Funding; Novartis: Honoraria; Bristol-Myers-Squibb: Consultancy, Honoraria; Pfizer: Honoraria, Research Funding; Roche: Honoraria, Research Funding; Sanofi Aventis: Honoraria; Eisai: Honoraria; Amgen: Honoraria, Research Funding. Greiner:BMS: Research Funding. Paschka:ASTEX Pharmaceuticals: Consultancy; Novartis: Consultancy; Medupdate GmbH: Honoraria; Bristol-Myers Squibb: Honoraria; Pfizer Pharma GmbH: Honoraria; Celgene: Honoraria. Heuser:Bayer Pharma AG: Research Funding; Karyopharm Therapeutics Inc: Research Funding; Novartis: Consultancy, Research Funding; Celgene: Honoraria; Pfizer: Research Funding; BerGenBio: Research Funding; Tetralogic: Research Funding.
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Hung, Tran Trong, Tran Anh Tu, Dang Thuong Huyen, and Marc Desmet. "Presence of trace elements in sediment of Can Gio mangrove forest, Ho Chi Minh city, Vietnam." VIETNAM JOURNAL OF EARTH SCIENCES 41, no. 1 (January 8, 2019): 21–35. http://dx.doi.org/10.15625/0866-7187/41/1/13543.
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Can Gio mangrove forest (CGM) is located downstream of Ho Chi Minh City (HCMC), situated between an estuarine system of Dong Nai - Sai Gon river and a part of Vam Co river. The CGM is the largest restored mangrove forest in Vietnam and the UNESCO’s Mangrove Biosphere Reserve. The CGM has been gradually facing to numeric challenges of global climate change, environmental degradation and socio-economic development for the last decades. To evaluate sediment quality in the CGM, we collected 13 cores to analyze for sediment grain size, organic matter content, and trace element concentration of Cd, Cr, Cu, Ni, Pb, Zn. Results showed that trace element concentrations ranged from uncontaminated (Cd, Cu, and Zn) to very minor contaminated (Cr, Ni, and Pb). The concentrations were gradually influenced by suspended particle size and the mangrove plants.ReferencesAnh M.T., Chi D.H., Vinh N.N., Loan T.T., Triet L.M., Slootenb K.B.-V., Tarradellas J., 2003. Micropollutants in the sediment of Sai Gon – Dong Nai rivers: Situation and ecological risks. Chimia International Journal for Chemistry, 57, 09(0009–4293), 537–541.Baruddin N.A., Shazili N.A., Pradit S., 2017. Sequential extraction analysis of heavy metals in relation to bioaccumulation in mangroves, Rhizophora mucronata from Kelantan delta, Malaysia. AACL Bioflux, 10(2), 172-181. Retrieved from www.bioflux.com/aacl.Bravard J.-P., Goichot M., Tronchere H., 2014. An assessment of sediment transport processes in the lower Mekong river based on deposit grain size, the CM technique and flow energy data. Geomorphology, 207, 174-189.Cang L.T., Thanh N.C. 2008. Importing and exporting sediment to and from mangrove forest at Dong Trang estuary, Can Gio district, Ho Chi Minh city. Science & Technology Development, 11(04), 12-18.Carignan J., Hild P., Mevelle G., Morel J., Yeghicheyan D., 2001. 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Gao, Burke, Shashank Dwivedi, Matthew D. Milewski, and Aristides I. Cruz. "CHRONIC LACK OF SLEEP IS ASSOCIATED WITH INCREASED SPORTS INJURY IN ADOLESCENTS: A SYSTEMATIC REVIEW AND META-ANALYSIS." Orthopaedic Journal of Sports Medicine 7, no. 3_suppl (March 1, 2019): 2325967119S0013. http://dx.doi.org/10.1177/2325967119s00132.
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Background: Although sleep has been identified as an important modifiable risk factor for sports injury, the effect of decreased sleep on sports injuries in adolescents is poorly studied. Purpose: To systematically review published literature to examine if a lack of sleep is associated with sports injuries in adolescents and to delineate the effects of chronic versus acute lack of sleep. Methods: PubMed and EMBASE databases were systematically searched for studies reporting statistics regarding the relationship between sleep and sports injury in adolescents aged <19 years published between 1/1/1997 and 12/21/2017. From included studies, the following information was extracted: bibliographic and demographic information, reported outcomes related to injury and sleep, and definitions of injury and decreased sleep. Additionally, a NOS (Newcastle-Ottawa Scale) assessment and an evaluation of the OCEM (Oxford Center for Evidence-Based Medicine) level of evidence for each study was conducted to assess each study’s individual risk of bias, and the risk of bias across all studies. Results: Of 907 identified articles, 7 met inclusion criteria. Five studies reported that adolescents who chronically slept poorly were at a significantly increased likelihood of experiencing a sports or musculoskeletal injury. Two studies reported on acute sleep behaviors. One reported a significant positive correlation between acutely poor sleep and injury, while the other study reported no significant correlation. In our random effects model, adolescents who chronically slept poorly were more likely to be injured than those who slept well (OR 1.58, 95% CI 1.05 to 2.37, p = 0.03). OCEM criteria assessment showed that all but one study (a case-series) were of 2b level of evidence—which is the highest level of evidence possible for studies which were not randomized control trials or systematic reviews. NOS assessment was conducted for all six cohort studies to investigate each study’s individual risk of bias. Five out of six of these studies received between 4 to 6 stars, categorizing them as having a moderate risk of bias. One study received 7 stars, categorizing it as having a low risk of bias. NOS assessment revealed that the most consistent source of bias was in ascertainment of exposure: all studies relied on self-reported data regarding sleep hours rather than a medical or lab record of sleep hours. Conclusions: Chronic lack of sleep in adolescents is associated with greater risk of sports and musculoskeletal injuries. Current evidence cannot yet definitively determine the effect of acute lack of sleep on injury rates. Our results thus suggest that adolescents who either chronically sleep less than 8 hours per night, or have frequent night time awakenings, are more likely to experience sports or musculoskeletal injuries. [Figure: see text][Figure: see text][Table: see text][Table: see text][Table: see text] References used in tables and full manuscript Barber Foss KD, Myer GD, Hewett TE. Epidemiology of basketball, soccer, and volleyball injuries in middle-school female athletes. Phys Sportsmed. 2014;42(2):146-153. Adirim TA, Cheng TL. Overview of injuries in the young athlete. Sports Med. 2003;33(1):75-81. Valovich McLeod TC, Decoster LC, Loud KJ, et al. National Athletic Trainers’ Association position statement: prevention of pediatric overuse injuries. J Athl Train. 2011;46(2):206-220. Milewski MD, Skaggs DL, Bishop GA, et al. Chronic lack of sleep is associated with increased sports injuries in adolescent athletes. J Pediatr Orthop. 2014;34(2):129-133. Wheaton AG, Olsen EO, Miller GF, Croft JB. 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Zeidan, Amer M., Maria R. Baer, Steven D. Gore, Medha Sasane, Carole Paley, Diane L. McNally, and Amy J. Davidoff. "Utilization Patterns of Iron Chelation Therapy in Transfusion-Dependent Myelodysplastic Syndrome Patients Enrolled in Medicare Part D." Blood 120, no. 21 (November 16, 2012): 3178. http://dx.doi.org/10.1182/blood.v120.21.3178.3178.
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Abstract Abstract 3178 Background: Anemia is present in up to 90% of patients (pts) with myelodysplastic syndromes (MDS), with as many as 40% developing red blood cell (RBC) transfusion-dependency. Though studies have reported clinical utility of iron chelation therapy (ICT) in MDS pts, its impact on overall survival from prospective studies is yet to be demonstrated. Reflective of this therapeutic equipoise and lack of uniform recommendations in the published guidelines, clinical utilization practices vary significantly. To better understand the utilization patterns of ICT, we conducted a retrospective analysis of a large transfusion-dependent MDS cohort enrolled in Medicare Part D from 2005 to 2008. Methods: MDS pts were identified using ICD-9 CM codes (1 inpatient or 2 outpatient) from a 100% Medicare sample. Pts meeting a minimum transfusion threshold of cumulative 20 packed RBC were considered “ICT eligible”. The study cohort consisted of ICT-eligible pts enrolled in Medicare Part D, allowing characterization of oral drug use. The observation period began the week (wk) after pts met the transfusion threshold and lasted until death or end of study. Transfusion use was captured based on specific Health Care Common Procedure Coding System (HCPCS) or revenue codes. Use of drugs, including ICT, was captured using specific HCPCS and National Drug Code (NDC) codes in Medicare Part B and D claims. Age at MDS diagnosis, race, and sex were determined from Medicare enrollment files. Logistic regression models were used to identify correlates of ICT use. Results: Among 125,290 MDS pts, 12,691 met the minimum transfusion threshold and were considered ICT eligible. Of those, 5,079 (40%) were enrolled in Medicare Part D and constituted the study cohort. In the study cohort, 65.6% of pts were ≥75 years old, 90% white, 47.8% males, and 13.9% had a poor predicted performance status (PS). MDS was classified as low-risk in 13.1%, 5q deletion-associated in 2.1%, high-risk in 6.9%, and not otherwise specified (NOS) in 77.9%. Common comorbidities included coronary artery disease (47.9%), congestive heart failure [CHF] (43.6%), cardiac conduction disorders or arrhythmias (44%), and renal disease (35.5%). The median follow-up was 95 wks (range 2–208). Pts were transfused a median of 13 (range 0–369) additional RBC units during the observation period. Among the entire study cohort, 793 patients (15.6%) received ICT; 513 (10.3%) received only deferasirox (DFX), 187 (3.8%) received only deferoxamine (DFO), and 93 (1.9%) received both. Median time from cohort entry to ICT initiation was 18 wks. The average dose for DFO was 2,932 mg/wk and for DFX, 1300 mg daily, relative to recommended levels of 10,000–14,000 mg/wk for DFO and 1,000–2,000 mg/daily for DFX. Median ICT therapy duration was 11 wks (1–168) for DFO, and 19 wks (1–139) for DFX. ICT was received for <26 wks in 60% of DFO and 57% of DFX users. Among ICT users, 71%, 37%, and 21%, received erythropoiesis-stimulating agents, hypomethylating agents (HMAs) and lenalidomide, respectively, during the observation period. No significant differences in ICT use were seen between low-risk, 5q deletion, and high-risk MDS pts (13.9% vs. 11.5% vs. 15.8%, P=0.52). In multivariate analysis using Cox proportional hazard models, the following were negatively associated with probability of receiving of ICT: age ≥ 90 years (Hazard ratio [HR] 0.557, 95%CI 0.347–0.894), female gender (HR 0.781, 95%CI 0.672–0.906), poor predicted PS (HR 0.725, 95%CI 0.541–0.972), history of CHF (HR 0.817, 95%CI 0.679–0.982), cardiac conduction disorders and arrhythmias (HR 0.824, 95%CI 0.694–0.979), and renal disease (HR 0.758, 95%CI 0.632–0.910). The likelihood of receiving ICT was higher among African American pts relative to whites (HR 1.579, 95%CI 1.157–2.156), residents of the South 2000 Census region (HR 1.27, 95%CI 1.005–1.604), and those pts receiving HMAs (HR 1.026, 95%CI 1.018–1.033) or lenalidomide (HR 1.007, 95%CI 1.003–1.012). Conclusions: Overall, ICT utilization rates among elderly transfusion-dependent MDS pts and among those with significant comorbidities were low. Also, ICT therapy was more likely to be of short duration among the elderly. Utilization rates were higher for DFX than DFO, and doses closer to recommended levels for DFX than DFO, likely reflecting greater ease of administration. Disclosures: Baer: Novartis, Inc.: Research Funding; Celgene, Inc.: Research Funding. Gore:Celgene Corporation: Consultancy, Research Funding. Sasane:Novartis Pharmaceuticals: Employment. Paley:Novartis: Employment. Davidoff:Celgene: Equity Ownership, Research Funding; National Institutes of Health: Research Funding; Novartis: Research Funding; GlaxoSmithKline: Research Funding.
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Seah, Shi Jie, Siat Ling Jong, Hong Yin Lam, and Jafri Din. "Rain fade margin of terrestrial line-of-sight (LOS) links for 5G networks in Peninsular Malaysia." International Journal of Microwave and Wireless Technologies, May 19, 2021, 1–11. http://dx.doi.org/10.1017/s1759078721000751.
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Abstract Advanced telecommunication systems are moving toward a high data transfer rate and wider bandwidth. The 5G communication network has recently been implemented for such aims. However, 5G networks operating with high operating frequency (typically above 20 GHz) could lead to impairments because of the atmospheric phenomena mainly precipitation and especially heavy rain. To address this, an optimum rain fade margin for the 5G network in Peninsular Malaysia is proposed using 77 sites of the rain-gauge network, which convert 1-h rain data to 1-min rain data by means of the international telecommunication union recommendation (ITU-R) P.837-7 model. Long-term rain attenuation statistics are obtained from ITU-R P.530-17 and the synthetic storm technique. The predicted rain attenuation is also presented in monthly statistics and in rain attenuation contour maps. The analysis showed that at 99.99% of link availability, the optimum rain fade margin operating at 26 GHz link should be in the range of 6.50 to 10 dB and 7 to 11 dB at 28 GHz link for a 5G network. Such information is useful for network operators and system engineers for the operation of 5G terrestrial microwave links in heavy rain regions.
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Abiola Semire, Folasade, Adeyanju Adekunle, and Robert Olayimika Abolade. "A Study on Rain Rate Prediction of Southwestern Nigeria." Physical Science International Journal, January 14, 2020, 1–12. http://dx.doi.org/10.9734/psij/2019/v23i430166.
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Rainfall parameters can be utilized to investigate the effect of climate change through scientific methods. However, data on rainfall rate exceeded for a fraction of an average year is grossly unavailable over Nigeria’s climate, thereby diminishing the capability of existing models to adequately estimate the effect of degradation due to rain. Hence, more accurate estimation is required for better predictions. Rainfall volume data for six different locations in the south-western region of Nigeria were obtained for rain rate computation using Semire and Rosmiwati model. The curve-fitted Cumulative Distribution Functions were compared with the ITU-R rain rate model (Recommendation P.837-6) and compensation function was obtained using error analysis while the performance was evaluated with respect to existing models using Chi-square, and Percentage Error and Root Mean Square Error (RMSE) metrics. The outcome of this study can be adopted for better understanding of spatial rainfall intensity in this region and other climatic zones of similar rainfall characteristics.
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Deschasaux, M., L. Bourhis, E. Chazelas, C. Debras, S. Hercberg, P. Latino-Martel, C. Julia, E. Kesse-Guyot, B. Srour, and M. Touvier. "Adherence to the new WCRF cancer prevention recommendations associates with a decreased cancer risk." European Journal of Public Health 30, Supplement_5 (September 1, 2020). http://dx.doi.org/10.1093/eurpub/ckaa165.1261.
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Abstract Background Cancer remains one of the leading causes of death worldwide. In 2018, following its summary report, the World Cancer Research Fund (WCRF) issued its recommendations for cancer prevention based on the nutritional risk factors with a sufficient level of evidence. Our objective was to study whether adherence to these new recommendations leads to a reduced risk of cancer. Methods This study included 80,604 participants from the NutriNet-Santé population-based cohort study (2009-2019). Adherence to the 2018 WCRF recommendations was assessed using the operationalized score on a 7-point scale, proposed by Shams-White et al (Nutrients 2019), including: weight, physical activity, fruit and vegetables, dietary fibers, ultra-processed foods, red and processed meat, sugary drinks and alcohol. Usual dietary intakes were assessed using repeated 24h-dietary records and physical activity level using the IPAQ questionnaire. Multi-adjusted Cox proportional hazard models were used for the analyses. Results A total of 2,438 incident cancer cases were diagnosed during follow-up (median: 7.4 years). The median WCRF 2018 adherence score was 3.75 (IQR: 3.25-4.50). An increase of 1-point increment in the score was associated with a decreased risk of cancer overall (HR = 0.90; 95%CI 0.86-0.90; P<.0001), and of obesity-related cancers (n = 1549 cases, HR = 0.89; 0.84-0.94; P<.0001), aerodigestive cancers (n = 390, HR = 0.83; 0.74-0.93; P = 0.001), breast cancer (n = 749, HR = 0.92; 0.85-1.00; P = 0.04) and a non-significant trends for prostate (n = 332, HR = 0.89; 0.79-1.01; P = 0.07) and colorectal (n = 218, HR = 0.88; 0.76-1.03; P = 0.1) cancers. Conclusions Our results suggest that a higher adherence to the WCRF 2018 recommendations for cancer prevention is associated to a decreased risk of cancer. Given the consistency between overall food-based dietary guidelines and the WCRF cancer recommendations, our result support their general promotion to the general public and transposition as public health actions. Key messages Following the recommendations for cancer prevention issued by the WCRF in 2018 can contribute to decrease the burden of cancer. The WCRF cancer recommendations are consistent with overall food-based dietary guidelines and should be promoted to the general public and transposed as public health actions.
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Makoveyenko, D. O. "FEATURES OF PLANNING SINGLE-FREQUENCY NETWORKS OF DIGITAL RADIO BROADCASTING TO COVER ROADS." Digital Technologies, 2020, 78–84. http://dx.doi.org/10.33243/2313-7010-28-78-84.
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An analysis of the world experience in the using of broadcasting networks has shown, that currently the most common digital terrestrial broadcasting technology in Europe is DAB / DAB +. The paper considers the results of research on the construction of a single-frequency synchronous network using DAB+ technology for coverage of highways on the example of the Kyiv - Odessa road. The influence of the network amplification effect is considered and quantitative estimates of the total gain in the statistical addition of signals from two transmitters are obtained. For the practical evaluation of the statistical network gain, control points are selected on the section of the route, where the predicted level of field strength from one transmitter is lower than the required value. Using the k-LNM method, it is determined that the resulting predicted value of the field strength exceeds the minimum required, and the corresponding probability of reception in all cases is greater than 99%. The radio coverage parameters of the reception were modeled, according to Recommendation ITU-R P.1812. A comparison of analog and digital radio coverage for the Kyiv-Odessa route showed that coverage in digital broadcasting mode for a 99% probability of reception is better than for analog broadcasting without installing additional transmitters or increasing the power used in analog broadcasting planning.
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Mohd Aris, Nor Azlan. "Rain Height Statistics from Spaceborne Radar for Satellite Communication in Malaysia." Jurnal Teknologi 58, no. 1 (June 18, 2012). http://dx.doi.org/10.11113/jt.v58.1520.
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Tropical and equatorial region exhibit significantly higher rainfall compared to the temperate region leading to higher attenuation for satellite communication links. One of the issues in radiowave propagation modeling is the different precipitation structures which play an important role in the estimation of rain fade. However, few results on rain height over Malaysian equatorial stations have been presented so far. To this aim, an investigation on rain height derived from Tropical Rainfall Measuring Mission (TRMM) Precipitation Radar (PR) is carried out. In this paper, the bright–band heights (hBB) have been analyzed to obtain monthly average values of the rain height (hR). TRMM PR is one of the most powerful instruments able to observe vertical profiles of rainfall. The analysis covers stratiform events around peninsular Malaysia. It is well known that hBB exists slightly below the 0°C isotherm height (h0) and this may lead to the estimation of rain height (hR). The obtained results on rain height are then compared with radiosonde observations and ITU–R Recommendation P.839–3. It is found that the bright–band height (hBB) appears to vary throughout the year and will mostly lie between 4192 m and 4593 m above mean sea level. The results suggest that by carefully consider the physical information of rain height derived from the various local databases should lead to substantial improvements in the rain attenuation prediction accuracy for equatorial and tropical region.
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Homoud, Mazen. "The Correlation Between Sleep Efficiency and the Risk of Obstructive Sleep Apnea." Internet Journal of Allied Health Sciences and Practice, 2014. http://dx.doi.org/10.46743/1540-580x/2014.1473.
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Purpose: The purpose of this correlation research was to identify the relationship between Obstructive Sleep Apnea (OSA) and sleep efficiency. Subjects: A total of six men and twelve women (N=18) form the College of Health Professions fulfilled the requirements for inclusion in this study. Method: This research integrated two investigation methods. 1) STOP-BANG questionnaire was completed by students and faculty from the College of Health Professions at Texas State University. Then, 2) each participant wore an Actigraphy watch for seven days. The result of the STOP-BANG questionnaire was compared to the result of the Actigraphy in regard to low or high risk of OSA and the normal or below normal sleep efficiency. Results: There was no significant relationship between the risk of having OSA according to STOP-BANG and sleep efficiency measured by Actigraphy watch in undiagnosed individuals (r =.240, p =.337). However, there was a positive, significant relationship between age and sleep efficiency. Conclusion and Recommendations: In order to improve the external validity, more participants need to be included in future research. Moreover, the use of medication that could affect sleep and alcohol consumption need to addressed. A full night sleep study in a sleep lab adds a standard for comparison. Finally, using other questionnaires or advanced forms of Actigraphy technology could provide better results.
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Iliff, Susan, Gaylene Tool, Patricia Bowyer, L. Parham, Tina Fletcher, and Wyona Freysteinson. "Self-Reflection and its Relationship to Occupational Competence and Clinical Performance in Level II Fieldwork." Internet Journal of Allied Health Sciences and Practice, 2021. http://dx.doi.org/10.46743/1540-580x/2021.1988.
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Purpose: Reflective practitioners embody the ability to critique their own clinical thinking about the dilemmas that frequently arise in professional practice and everyday life. Conflicting evidence exists on whether or not self-reflective practices are effective in promoting academic, clinical, and personal success. This quantitative study investigated self-reflection as a predictor of increased occupational competence and clinical performance in Level II Fieldwork for entry-level Master's degree occupational therapy students. Method: The study used convenience sampling to recruit participants and data were collected via a demographic survey and self-assessment questionnaires. Multiple linear regression analyses were conducted to determine the extent to which self-reflection predicts occupational competence and clinical performance. R2 values were examined to determine the importance of each dependent variable (occupational competence and clinical performance). Results: Findings revealed a statistically significant relationship between self-reflection and occupational competence (p = 0.0053) but not between self-reflection and clinical performance (p = 0.08). Self-reflection accounted for 14% of the variance in clinical performance (R2 = 0.14), and more than one third (R2 = 0.38) of the variance in occupational competence. Results suggest that students who self-reflect regularly during fieldwork may have a greater ability to maintain everyday life routines during the demands of Level II Fieldwork. Conclusions: Self-reflection strongly predicts occupational competence of occupational therapy students during Level II Fieldwork, but does not significantly predict students’ clinical performance. Recommendations: Occupational therapy educators should consider incorporating guided self-reflection activities into the academic program in order to support student occupational competence. Intentional coaching in self-reflection may better prepare students for a clinical setting by supporting healthy daily routines, which may help them to manage stress during Level II Fieldwork. Future research should explore the impact of self-reflection training during clinical rotations (provided by clinical educators) on student clinical performance. Revision of the measurement of clinical performance is warranted to include questions pertaining to soft skills such as self-reflection and awareness.
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Brito, Lívia Natália Sales, Thayanara Silva Melo, Mário Luciano de Mélo Silva Júnior, and Gustavo Pina Godoy. "Uso de enxaguante bucal na prática odontológica durante a pandemia de COVID-19." ARCHIVES OF HEALTH INVESTIGATION 9, no. 4 (October 6, 2020). http://dx.doi.org/10.21270/archi.v9i4.5150.
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Introdução: A transmissão SARS-CoV-2 de humano para humano pode ocorrer e o risco de propagação no ar durante os procedimentos odontológicos geradores de aerossóis permanece uma preocupação. Acredita-se que um enxaguatório bucal antimicrobiano pré-operacional reduza o número de micróbios orais. No entanto, a eficácia do enxaguatório bucal pré-procedimento na redução do número de microrganismos disseminados por meio do aerossol gerado por procedimentos odontológicos ainda não está clara. Objetivo: avaliar através de uma revisão de literatura o uso de enxaguantes bucais na redução da carga viral do SARS-CoV-2. Materiais e Método: O levantamento literário para esta pesquisa foi realizado no período de dezembro de 2019 a 10 de agosto de 2020 nas bases de dados Scielo e Medline/PubMed. Na estratégia de busca, foram utilizadas as palavras “SARS-CoV-2”, “2019-nCoV”, “COVID-19”, “Dentistry”, “Odontologia”, “Odontología”, “Mouthwashes”, “Antissépticos Bucais” e “Antisépticos Bucales”. Resultados: Uma busca sistematizada foi realizada, foram encontrados 661 artigos, após a realização da leitura criteriosa dos artigos completos foram selecionados 42 artigos. 88% dos estudos indicavam o uso de Peróxido de hidrogênio a 1%, 76% indicavam Povidine 0,2% e apenas 19% o uso da Clorexidina a 0,12%. Conclusão: Os estudos presentes na literatura apresentam divergências nas indicações e porcentagens dos enxaguantes indicados. Os protocolos clínicos devem ser avaliados para reduzir o risco de transmissão e proteger pacientes e profissionais.Descritores: Infecções por Coronavírus; Betacoronavirus; Odontologia; Antissépticos Bucais.ReferênciasGe ZY, Yang LM, Xia JJ, Fu XH, Zhang YZ. Possible aerosol transmission of COVID-19 and special precautions in dentistry. J Zhejiang Univ Sci B. 2020;21(5):361-68. Peng X, Xu X, Li Y, Cheng L, Zhou X, Ren B. Transmission routes of 2019-nCoV and controls in dental practice. 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Oral Dis. 2020;10.1111/odi.13526.Marui VC, Souto MLS, Rovai ES, Romito GA, Chambrone L, Pannuti CM. Efficacy of preprocedural mouthrinses in the reduction of microorganisms in aerosol: A systematic review. J Am Dent Assoc. 2019;150(12):1015-26.e1.