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Dissertations / Theses on the topic 'Recovery of motor function after stroke'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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1

Askim, Torunn. "Recovery after stroke - assessment and treatment; with focus on motor function." Doctoral thesis, Norwegian University of Science and Technology, Department of Public Health and General Practice, 2008. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-2089.

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<p>The incidence of stroke has not changed significantly in recent decades. However, the actual number of strokes is likely to increase as a consequence of the increasing number of elderly people, creating a significant burden on the health care system, the patients and their families. Pareses are the most common impairment reported after stroke. Motor impairments are associated with reduced self-perceived health, and consequently rehabilitation after stroke has a strong emphasis on physiotherapy and motor training. However, more knowledge about motor recovery and effects of therapy is needed

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2

Calautti, Cinzia. "A functional Magnetic Resonance Imaging study of recovery after stroke : assessing distinct components of hand motor function." Thesis, University of Cambridge, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.612003.

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3

Turton, Ailie Jean. "The contribution of reorganised motor pathways to recovery of arm and hand function after stroke." Thesis, Open University, 1996. http://oro.open.ac.uk/57650/.

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Stroke often disrupts the descending motor pathways controlling the upper limb with severe consequences for patients' hand function. Although some recover they are often slow and clumsy when using the affected hand. The mechanism underlying recovery is an unsettled question. Transcranial magnetic stimulation (TMS) was used to determine the changes in the connectivity and function of the corticospinal tract (CST) that are associated with improved motor performance in the recovering arm and hand. The study comprised four parts: 1. Task dependency of responses to TMS in recovered stroke patients.

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4

Rubio, Ballester Belén. "VR-based rehabilitation strategies for functional motor recovery after stroke: individualization, reinforcement, and transfer." Doctoral thesis, Universitat Pompeu Fabra, 2016. http://hdl.handle.net/10803/392145.

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Stroke represents one of the main causes of adult disability and will be one of the main contributors to the burden of disease in 2030. However, our healthcare systems do not have enough resources to cover the current demand let alone its future increase. Partial and unmet rehabilitation needs may ultimately lead to a loss of functional independence. Hence, it is essential that new approaches are deployed that help to manage these chronic conditions and augment current rehabilitation approaches in order to enhance their e ciency. One of the latest approaches in the rehabilitation of a

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5

Heald, Andrew. "Longitudinal study of central motor conduction as a predictor of functional recovery after stroke." Thesis, University of Newcastle Upon Tyne, 1994. http://hdl.handle.net/10443/638.

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Central motor conduction was assessed as a predictor of mortality and functional outcome in a longitudinal study of 118 patients with first-ever stroke. Investigations commenced 12-72 hours after stroke and were repeated up to death or 12 months. The results were compared with normal data, validated assessments of motor function, detailed neurological examinations and CT scans. Responses were recorded in the surface electromyogram from proximal and distal muscles of both upper limbs following percutaneous electromagnetic stimulation of the motor cortex (muscles contracted) and spinal motor roo

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6

Mares, Kathryn. "Investigations of physical therapy interventions to enhance movement recovery in people after stroke : development and design of a novel intervention embedding Functional Strength Training within a motor learning context." Thesis, University of East Anglia, 2013. https://ueaeprints.uea.ac.uk/52519/.

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Stroke is the largest cause of adult disability in the UK and stroke survivors commonly present with a partial or complete loss of movement. Physical therapy interventions as part of movement rehabilitation after stroke aim to facilitate a return to participation in activities of daily living. It has been proposed that the processes that underpin both movement recovery following stroke and motor learning are the same. By embedding physical therapies within a motor learning context it is possible that the effects of the therapy could be enhanced. Yet the application of motor learning principles

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7

Vass, Catherine D. "Recovery of arm function after stroke." Thesis, University of Nottingham, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.342501.

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8

Richter, Grant. "Gaba Drugs For Motor Recovery After Stroke." Thesis, The University of Sydney, 2021. https://hdl.handle.net/2123/25088.

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Clinical reports describe a rare but striking recovery of brain function post stroke after taking the non-benzodiazepine ‘Z-drug’ zolpidem. The underlying mechanism for this is still unknown. This body of work investigates the relationship of Z-drugs and stroke and serves three purposes. Firstly, it furthers our understanding of the particular GABAA receptor subtypes Z-drugs modulate. Benzodiazepines bind between the α-γ2 subunit interfaces (where α is α1, α2, α3, or α5). An analogous binding site is present when γ2 is substituted for γ1 or γ3 but has limited and conflicting pharmacological i

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9

Sonde, Lars. "Rehabilitation after stroke : effects of length of stay and treatments to facilitate motor recovery after stroke /." Stockholm, 2001. http://diss.kib.ki.se/2001/91-628-4730-9/.

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10

Kirkland, Scott, and University of Lethbridge Faculty of Arts and Science. "Modulation of recovery and compensation after stroke." Thesis, Lethbridge, Alta. : University of Lethbridge, Faculty of Arts and Science, 2007, 2007. http://hdl.handle.net/10133/387.

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Stress has been shown to exacerbate cell death and cognitive deficits after ischemic injury in rodents, however, little is known of the effects of stress on motor recovery. The objective of this present thesis is to examine the effects of chronic stress on skilled motor recovery after devascularization lesion in rats. It was found that pre-lesion stress induced the most behavioural impairments, while post-lesion stress exacerbated infarct volume. The effects of chronic multiple stress on skilled motor recovery after lesion was also examined. Chronic multiple stress did not modulate skilled mot

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11

Kokotilo, Kristen J. "Reorganization of brain function during force production after stroke." Thesis, University of British Columbia, 2008. http://hdl.handle.net/2429/2723.

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Damage to motor areas of the brain, caused by stroke, can produce devastating motor deficits, including aberrant control of force. After stroke, reorganization of the brain’s motor system has been identified as one of the fundamental mechanisms involved in recovery of motor control after stroke. Yet, few studies have investigated how force production and modulation are encoded in the brain after stroke and how this relates to motor outcome. Thus, the purpose of this study was to (1) understand how past neuroimaging literature has contributed to establishing common patterns of brain reorganizat

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12

Leong, Ka Wai. "The dynamic relationship between neural plasticity and motor function after stroke." Thesis, McGill University, 2009. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=40756.

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Numerous post-stroke rehabilitative approaches developed to date have only limited effectiveness in improving upper extremity function in the post-acute stage of stroke. This limited effectiveness can be partly attributed to the complex interaction between neuronal injury and the mechanisms of motor recovery. This study examined the extent to which motor functions and neurophysiological measures fluctuate over the course of nine sessions of repetitive transcranial magnetic stimulation in seven chronic stroke patients. Improvement in motor function occurred early during intervention. This was a

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13

Plant, R. D. "Central nervous control of the upper limb after stroke." Thesis, University of Newcastle Upon Tyne, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.315634.

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14

Sommerfeld, Disa. "Body function and activity after acute stroke : physiotherapy perspectives /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7349-828-9/.

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15

Sawada, Masahiro. "Function of the nucleus accumbens in motor control during recovery after spinal cord injury." Kyoto University, 2017. http://hdl.handle.net/2433/218001.

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16

Pendlebury, Sarah Tamsin. "Patterns of damage and recovery in the motor system after ischaemic stroke : a magnetic resonance study." Thesis, University of Oxford, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.365767.

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17

Lee, Karah S. H. "Ablation of Progenitor Cells Does Not Impede Motor Recovery or Diminish Cognitive Function Following a Focal Cortical Stroke." Thesis, Université d'Ottawa / University of Ottawa, 2016. http://hdl.handle.net/10393/34466.

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Following a stroke there is a significant increase in the number and migration of progenitor cells (PCs) to the infarct, and positive correlations between neurogenesis and recovery. Loss-of-function studies have conflicting findings on whether the ablation of PCs impedes motor or cognitive function post-stroke. This thesis examines if neurogenesis per se is required for motor recovery and spatial learning and memory. PCs were ablated in an adult GFAP-TK rat model that allows for the inducible deletion of GFAP-expressing PCs in the brain. An endothelin-1 (ET-1) stroke was produced and assessmen

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18

Humm, Jennifer Leigh. "Behavior-dependent neural events and adult neurogenesis : contributions to recovery of motor function after cortical injury /." Digital version accessible at:, 2000. http://wwwlib.umi.com/cr/utexas/main.

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19

Salmon, Elizabeth. "DEVELOPMENT OF AN EEG BRAIN-MACHINE INTERFACE TO AID IN RECOVERY OF MOTOR FUNCTION AFTER NEUROLOGICAL INJURY." UKnowledge, 2013. http://uknowledge.uky.edu/cbme_etds/8.

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Impaired motor function following neurological injury may be overcome through therapies that induce neuroplastic changes in the brain. Therapeutic methods include repetitive exercises that promote use-dependent plasticity (UDP), the benefit of which may be increased by first administering peripheral nerve stimulation (PNS) to activate afferent fibers, resulting in increased cortical excitability. We speculate that PNS delivered only in response to attempted movement would induce timing-dependent plasticity (TDP), a mechanism essential to normal motor learning. Here we develop a brain-machine i

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20

Welmer, Anna-Karin. "Associations between body functions, activities and health related quality of life from onset until 18 months after stroke /." Stockholm : Karolinska institutet, 2007. http://diss.kib.ki.se/2007/978-91-7357-413-6/.

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21

Hammer, Ann M. "Forced use on arm function after stroke : clinically rated and self-reported outcome and measurement during the sub-acute phase." Doctoral thesis, Örebro universitet, Hälsoakademin, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-9601.

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The overall aim was to evaluate the effectiveness of forced use on arm and hand recovery after stroke by applying a restraining sling on the non-affected arm and to investigate psychometric properties of selected upper limb measures. Papers I and II reported a randomised trial with 1- and 3-month follow-ups. Thirty patients 1 to 6 months after stroke were included and received regular training for 2 weeks of intervention. The forced-use group had in addition a restraining sling on the non-paretic arm. Outcome measures were the Fugl-Meyer Assessment, the Modified Ashworth scale, the 16-hole peg

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22

Elsner, Bernhard, Gert Kwakkel, Joachim Kugler, and Jan Mehrholz. "Transcranial direct current stimulation (tDCS) for improving capacity in activities and arm function after stroke: a network meta-analysis of randomised controlled trials." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2018. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-232467.

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Background: Transcranial Direct Current Stimulation (tDCS) is an emerging approach for improving capacity in activities of daily living (ADL) and upper limb function after stroke. However, it remains unclear what type of tDCS stimulation is most effective. Our aim was to give an overview of the evidence network regarding the efficacy and safety of tDCS and to estimate the effectiveness of the different stimulation types. Methods: We performed a systematic review of randomised trials using network meta-analysis (NMA), searching the following databases until 5 July 2016: Cochrane Central Regi

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Elsner, Bernhard, Gert Kwakkel, Joachim Kugler, and Jan Mehrholz. "Transcranial direct current stimulation (tDCS) for improving capacity in activities and arm function after stroke: a network meta-analysis of randomised controlled trials." BioMed Central, 2017. https://tud.qucosa.de/id/qucosa%3A30748.

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Background: Transcranial Direct Current Stimulation (tDCS) is an emerging approach for improving capacity in activities of daily living (ADL) and upper limb function after stroke. However, it remains unclear what type of tDCS stimulation is most effective. Our aim was to give an overview of the evidence network regarding the efficacy and safety of tDCS and to estimate the effectiveness of the different stimulation types. Methods: We performed a systematic review of randomised trials using network meta-analysis (NMA), searching the following databases until 5 July 2016: Cochrane Central Regi

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24

Assis, Rodrigo Deamo [UNIFESP]. "Análise comparativa entre as escalas funcionais do membro superior WMFT e ARAT utilizadas na avaliação da terapia por contensão induzida em pacientes com AVC isquêmico." Universidade Federal de São Paulo (UNIFESP), 2008. http://repositorio.unifesp.br/handle/11600/8898.

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Made available in DSpace on 2015-07-22T20:49:20Z (GMT). No. of bitstreams: 0 Previous issue date: 2008-07-30<br>Introdução: A Terapia por Contensão Induzida (TCI) ou Constraint-induced Movement Therapy é uma intervenção que tem como objetivo a recuperação do membro superior afetado de pacientes hemiparéticos devido à lesão encefálica. É aplicada através de um tratamento intensivo durante duas semanas consecutivas, com seis horas diárias de exercícios e uso de uma tipóia, durante 90% do dia, no membro superior não-afetado. O ganho motor da TCI é validado através das escalas funcionais de ava

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25

Valkenborghs, Sarah. "Enhancing the efficacy of task-specific training on upper limb motor recovery after stroke." Thesis, 2019. http://hdl.handle.net/1959.13/1402475.

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Research Doctorate - Doctor of Philosophy (PhD)<br>Background: Many people after stroke are left with chronic upper limb impairment which affects their ability to perform even basic activities of daily living. Upper limb impairment is a major contributor to poor well-being and quality of life and advancing therapy for upper limb recovery is a research priority. To date, task-specific training has demonstrated the most promise, but effect sizes are usually small. Objective: This thesis includes three distinct but complementary studies aiming to address the overarching research question, “Can th

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26

Gopaul, Urvashy. "Combined somatosensory and motor training to improve upper limb recovery after stroke." Thesis, 2019. http://hdl.handle.net/1959.13/1407593.

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Research Doctorate - Doctor of Philosophy (PhD)<br>Background: Stroke is a leading cause of disability worldwide. Upper limb motor and somatosensory impairments are common following stroke, making performance of everyday tasks difficult. Interventions directed at motor deficits have traditionally been separated from interventions directed at somatosensory deficits. By treating motor and somatosensory impairments separately, the potential beneficial effects of combining somatosensory training to further enhance sensorimotor function and action are not utilised. Hence, there is a critical need f

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27

PICHIORRI, FLORIANA. "Brain-computer interface technology and neuroelectrical imaging to improve motor recovery after stroke." Doctoral thesis, 2019. http://hdl.handle.net/11573/1249958.

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Stroke is defined as a focal lesion in the brain caused by acute ischemia or hemorrhage. The events that characterize acute stroke as well as the spontaneous recovery process occurring in the subacute phase, demonstrate that the focal damage affects remote interconnected areas. On the other hand, interconnected areas largely contribute to reorganization of the central nervous system (CNS) along the recovery process (plasticity) throughout compensatory or restorative mechanisms which can also lead to unwanted effects (maladaptive plasticity). Such post-stroke brain reorganization occurring spon

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28

Cheng-ChangYang and 楊正昌. "Caffeine inhibits spontaneous motor function recovery after contusion spinal cord injury." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/04131904746953979685.

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博士<br>國立成功大學<br>基礎醫學研究所<br>104<br>Spinal cord injury (SCI) results in paralysis and organ impairment. The pathology of SCI includes primary and secondary injury that is involved in neurological dysfunction. Primary injury of SCI refers to an injury that is directly caused by a physical or chemical insults; whereas, secondary injury refers to injuries that are caused by primary injury-induced subsequent events, such as inflammation, oxidative stress and apoptosis. SCI therapy has been focused on preventing secondary injury to reduce lesion area so that functional outcome after a SCI may be impr

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29

Brima, Tufikameni. "Changes in motor function and seizure susceptibility after photothrombic ischemic stroke in immature rat." Doctoral thesis, 2012. http://www.nusl.cz/ntk/nusl-308891.

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i | P a g e ABSTRACT Changes in motor function and seizure susceptibility after photothrombic ischemic stroke in immature rat Perinatal stroke is a common cerebrovascular disorder affecting one in every 4000 births, typically associated with sequelae that include motor and cognitive deficits and long term comorbidities including epilepsy. We sought to determine the effect of perinatal induced stroke on motor function and seizure susceptibility in rats. Photothrombotic model of stroke was used in rat at postnatal day 7. Firstly we induced ischemic lesions of different extends to assess the cons

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30

Wang, Yun-Ting, and 王韻婷. "Effects of Forelimb Electrical Stimulation on Motor Function and Brain Recovery in Acute Stroke – Middle Cerebral Artery Occlusion Rat Model." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/3ygfg3.

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碩士<br>國立陽明大學<br>物理治療暨輔助科技學系<br>104<br>Background: Electrical stimulation (ES) is known to promote the recovery of motor function in rats with brain ischemia and to increase the expression of growth factors, which support neurogenesis in the brain. However, it is not known whether ES is beneficial or detrimental during acute brain ischemia. In this study, the ES effects on motor function and brain infarct volume after acute brain ischemia in rats were investigated. Methods: Adult male Sprague-Dawley rats underwent middle cerebral artery occlusion (MCAO) first and were then randomly assigned to

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31

Tomov, Toma L. "Effects of altered trigeminal sensory and motor cortical input on the recovery of function after facial nerve repair in rats /." 2008. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=016427373&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.

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32

Zhu, Jun Ding, and 朱俊鼎. "A Comparative Study of Action Observation Therapy and Mirror Therapy on Motor Function and Neural Mechanisms After Subacute Stroke: A Case Series." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/7dwphm.

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碩士<br>長庚大學<br>職能治療學系<br>105<br>Introduction: Stroke is an important health issue worldwide. Patients with stroke commonly have unilateral upper-limb (UL) motor impairments which result in long-term dependence of patients. Action observation therapy (AOT) is a new rehabilitation approach based on the mechanism of mirror neuron system (MNS). During AOT, patients were asked to observe the actions performed by another healthy person in the videos and imitate the actions intentionally. Mirror therapy (MT) is another recent prominent rehabilitation intervention. MT required patients to look at the r

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33

Roorda, L. D., J. R. Green, A. Houwink, et al. "Item hierarchy-based analysis of the Rivermead Mobility Index resulted in improved interpretation and enabled faster scoring in patients undergoing rehabilitation after stroke." 2012. http://hdl.handle.net/10454/6163.

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OBJECTIVE: To enable improved interpretation of the total score and faster scoring of the Rivermead Mobility Index (RMI) by studying item ordering or hierarchy and formulating start-and-stop rules in patients after stroke. DESIGN: Cohort study. SETTING: Rehabilitation center in the Netherlands; stroke rehabilitation units and the community in the United Kingdom. PARTICIPANTS: Item hierarchy of the RMI was studied in an initial group of patients (n=620; mean age +/- SD, 69.2+/-12.5y; 297 [48%] men; 304 [49%] left hemisphere lesion, and 269 [43%] right hemisphere lesion), and the adequacy of the

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34

Roorda, L. D., J. R. Green, A. Houwink, et al. "The Rivermead Mobility Index allows valid comparisons between subgroups of patients undergoing rehabilitation after stroke who differ with respect to age, sex, or side of lesion." 2012. http://hdl.handle.net/10454/6162.

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OBJECTIVE: To investigate differential item functioning or item bias of the Rivermead Mobility Index (RMI) and its impact on the drawing of valid comparisons with the RMI between subgroups of patients after stroke who differ with respect to age, sex, or side of lesion. DESIGN: Cross-sectional study. SETTING: A rehabilitation center in the Netherlands and 2 stroke rehabilitation units and the wider community in the United Kingdom. PARTICIPANTS: The RMI was completed for patients undergoing rehabilitation after stroke (N=620; mean age +/- SD, 69.2+/-12.5y; 297 [48%] men; 269 [43%] right hemisphe

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