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Journal articles on the topic 'Recovery of motor function after stroke'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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1

Bonita, R., and R. Beaglehole. "Recovery of motor function after stroke." Stroke 19, no. 12 (1988): 1497–500. http://dx.doi.org/10.1161/01.str.19.12.1497.

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2

Sharma, Nikhil, and Leonardo G. Cohen. "Recovery of motor function after stroke." Developmental Psychobiology 54, no. 3 (2010): 254–62. http://dx.doi.org/10.1002/dev.20508.

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3

Jiang, Lin, Huijuan Xu, and Chunshui Yu. "Brain Connectivity Plasticity in the Motor Network after Ischemic Stroke." Neural Plasticity 2013 (2013): 1–11. http://dx.doi.org/10.1155/2013/924192.

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The motor function is controlled by the motor system that comprises a series of cortical and subcortical areas interacting via anatomical connections. The motor function will be disturbed when the stroke lesion impairs either any of these areas or their connections. More and more evidence indicates that the reorganization of the motor network including both areas and their anatomical and functional connectivity might contribute to the motor recovery after stroke. Here, we review recent studies employing models of anatomical, functional, and effective connectivity on neuroimaging data to invest

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Starchina, Yu A. "Motor function recovery in patients after ischemic stroke." Neurology, Neuropsychiatry, Psychosomatics 11, no. 3S (2019): 89–94. http://dx.doi.org/10.14412/2074-2711-2019-3s-89-94.

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Secondary prevention of recurrent stroke and other cardiovascular diseases is of key importance for the management of a patient after ischemic stroke. Medications (antihypertensive, antiplatelet, or anticoagulant drugs and statins) are recommended for use; and a small proportion of patients should undergo surgical treatment (carotid endarterectomy); non-drug treatments (smoking cessation and alcohol abstinence, adherence to the Mediterranean diet, and increased physical activity) are of great importance. Movement disorders are seen in 80% of patients after a stroke and are the leading cause of

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5

Lu, Changbo, Xianglong Wu, Hongzhe Ma, et al. "Optogenetic Stimulation Enhanced Neuronal Plasticities in Motor Recovery after Ischemic Stroke." Neural Plasticity 2019 (March 14, 2019): 1–9. http://dx.doi.org/10.1155/2019/5271573.

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Motor capability recovery after ischemic stroke involves dynamic remodeling processes of neural connectomes in the nervous system. Various neuromodulatory strategies combining direct stimulating interventions with behavioral trainings for motor recovery after ischemic stroke have been developed. However, the effectiveness of these interventions varies widely due to unspecific activation or inhibition of undefined neuronal subtypes. Optogenetics is a functional and structural connection-based approach that can selectively activate or inhibit specific subtype neurons with a higher precision, and

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Salvalaggio, Silvia, Luisa Cacciante, Lorenza Maistrello, and Andrea Turolla. "Clinical Predictors for Upper Limb Recovery after Stroke Rehabilitation: Retrospective Cohort Study." Healthcare 11, no. 3 (2023): 335. http://dx.doi.org/10.3390/healthcare11030335.

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After stroke, recovery of upper limb (UL) motor function is enhanced by a high dose of rehabilitation and is supposed to be supported by attentive functions. However, their mutual influence during rehabilitation is not well known yet. The aim of this retrospective observational cohort study was to investigate the association between rehabilitation dose and motor and cognitive functions, during UL motor recovery. Inpatients with first unilateral stroke, without time restrictions from onset, and undergoing at least 15 h of rehabilitation were enrolled. Data on dose and modalities of rehabilitati

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7

Ward, N. S. "Mechanisms underlying recovery of motor function after stroke." Postgraduate Medical Journal 81, no. 958 (2005): 510–14. http://dx.doi.org/10.1136/pgmj.2004.030809.

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8

Stinear, Cathy. "Prediction of recovery of motor function after stroke." Lancet Neurology 9, no. 12 (2010): 1228–32. http://dx.doi.org/10.1016/s1474-4422(10)70247-7.

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9

Cramer, Steven C. "Changes in motor system function and recovery after stroke." Restorative Neurology and Neuroscience 22, no. 3-5 (2004): 231–38. https://doi.org/10.3233/rnn-2004-00254.

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Motor system impairments are common after stroke and are a major contributor to disability after stroke. Most patients show improvement in the weeks-months following a stroke. Understanding the neurobiological underpinnings of these behavioral gains may be useful for refining treatments that aim to improve outcome and reduce disability. A number of brain mapping studies have examined how stroke affects motor system function. Numerous changes have been identified in this setting and are reviewed herein, including reduced laterality, widespread changes across a distributed sensorimotor network,

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Takeuchi, Naoyuki, and Shin-Ichi Izumi. "Maladaptive Plasticity for Motor Recovery after Stroke: Mechanisms and Approaches." Neural Plasticity 2012 (2012): 1–9. http://dx.doi.org/10.1155/2012/359728.

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Many studies in human and animal models have shown that neural plasticity compensates for the loss of motor function after stroke. However, neural plasticity concerning compensatory movement, activated ipsilateral motor projections and competitive interaction after stroke contributes to maladaptive plasticity, which negatively affects motor recovery. Compensatory movement on the less-affected side helps to perform self-sustaining activity but also creates an inappropriate movement pattern and ultimately limits the normal motor pattern. The activated ipsilateral motor projections after stroke a

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Bunketorp-Käll, Lina, Marcela Pekna, Milos Pekny, Hans Samuelsson, Christian Blomstrand, and Michael Nilsson. "Motor Function in the Late Phase After Stroke: Stroke Survivors’ Perspective." Annals of Rehabilitation Medicine 44, no. 5 (2020): 362–69. http://dx.doi.org/10.5535/arm.20060.

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Objective To examine the association between observer-assessed functional status and perceived recovery in the late phase after stroke. The study also aimed to determine whether observer-assessed functional improvements as a result of horse-riding therapy (H-RT) are related to enhanced perception of stroke recovery.Methods This is a descriptive correlational study using data derived from a three-armed randomized controlled trial in which 123 individuals were enrolled, among whom 43 received H-RT for 12 weeks. The measures included the Modified Motor Assessment Scale, Berg Balance Scale, Timed

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Kadykov, A. S., and L. A. Chernikova. "Recovery of motor functions after a stroke." Neurology Bulletin XXX, no. 3-4 (2021): 50–51. http://dx.doi.org/10.17816/nb81051.

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The problem of rehabilitation of stroke patients is being actively developed in modern medicine. According to the World Health Organization, 100-300 cases of stroke occur annually in developed countries for every 100 thousand people. In Russia, these numbers are 250-320 among the urban population (according to the registers of cerebral stroke in Moscow and Novosibirsk) and 170 among the rural population (according to the Stavropol Territory).

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13

Yuan, Xiaoxia, Yuan Yang, Na Cao, and Changhao Jiang. "Promotion of Poststroke Motor-Function Recovery with Repetitive Transcranial Magnetic Stimulation by Regulating the Interhemispheric Imbalance." Brain Sciences 10, no. 9 (2020): 648. http://dx.doi.org/10.3390/brainsci10090648.

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Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive brain-stimulation technique that transiently modulates cerebral cortex excitability, achieving overall positive results in poststroke motor-function recovery. Excessive inhibition of the ipsilesional-affected hemisphere by the contralesional-unaffected hemisphere has seriously hindered poststroke motor-function recovery. Hence, intracortical disinhibition can be used as an approach to managing poststroke brain injury. This technique promotes neural plasticity for faster motor-function recovery. rTMS relieves unilateral inhibi

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Kayerova, Elena V., Natalya S. Zhuravskaya, Ekaterina A. Kozina, and Olga V. Shakirova. "Restoration of Upper Limb Motor Function After Stroke." Bulletin of Rehabilitation Medicine 20, no. 1 (2021): 21–26. http://dx.doi.org/10.38025/2078-1962-2021-20-1-21-26.

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Since the task of eliminating the consequences of a stroke remains unsolved, research on the use of robotic simulators equipped with feedback to restore upper limb motor functions is of particular relevance. Aim of the study was to conduct an experimental evaluation of the effectiveness of the use of the Anika sensory glove with biological feedback for the restoration of upper extremity motor function in the early period of ischemic stroke. Materials and methods. We analyzed 108 medical histories and selected 28 patients with a single history of stroke and moderate cognitive disorders, which w

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PSB, Roshan, Vishnu K Nair, Prathik ., and Bipin Wilson. "Effects of Mirror Therapy in Improving Motor Function After Stroke: A Literature Review." International Journal of Health Sciences and Research 15, no. 3 (2025): 104–9. https://doi.org/10.52403/ijhsr.20250317.

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Background: Stroke is a vascular disorder leading to focal cerebral dysfunction, often presenting as hemiplegia. Rehabilitation starts within 24 hours, focusing on motor recovery. Mirror therapy, a cost-effective treatment, enhances neuroplasticity by reflecting the unaffected limb’s movements to stimulate the affected limb. This visual feedback improves motor function and reduces pain, particularly in patients with complex regional pain syndrome. Strategies include active, mental, and passive movements, with lasting improvements in motor function observed up to six months post-treatment. Obje

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Ulya, Tuhfatul, Chrismawan Ardianto, Putri Anggreini, Aniek Setiya Budiatin, Dwi Setyawan, and Junaidi Khotib. "Quercetin promotes behavioral recovery and biomolecular changes of melanocortin-4 receptor in mice with ischemic stroke." Journal of Basic and Clinical Physiology and Pharmacology 32, no. 4 (2021): 349–55. http://dx.doi.org/10.1515/jbcpp-2020-0490.

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Abstract Objectives Ischemic stroke is known as a common causes of disability, lower psychological well-being as well as preventable death. The pathogenesis of ischemic stroke process becomes worse immediately after oxidative stress occurs. One of the flavonoids with antioxidant abilities is quercetin. This study was aimed to investigate quercetin administration on the behavioral functions (motor and sensory) and expression of melanocortin-4 receptor (MC4R) in mice with ischemic stroke. Methods Male ICR mice were divided into sham, stroke, stroke with quercetin 100, 150, and 200 mg/kg. The str

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Clarkson, Andrew N., Kim Parker, Michael Nilsson, F. Rohan Walker, and Emma K. Gowing. "Combined Ampakine and BDNF Treatments Enhance Poststroke Functional Recovery in Aged Mice via AKT-CREB Signaling." Journal of Cerebral Blood Flow & Metabolism 35, no. 8 (2015): 1272–79. http://dx.doi.org/10.1038/jcbfm.2015.33.

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Cerebral ischemia results in damage to neuronal circuits and lasting impairment in function. We have previously reported that stimulation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors with the ampakine, CX1837, increases brain-derived neurotrophic factor (BDNF) levels and affords significant motor recovery after stroke in young mice. Here, we investigated whether administration of CX1837 in aged (24 months old) mice was equally effective. In a model of focal ischemia, administration of CX1837 from 5 days after stroke resulted in a small gain of motor function by week 6 afte

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Kwak, Soyoung, Sang Gyu Kwak, and Min Cheol Chang. "The effect of preexisting heart failure and coronary artery disease on motor function recovery in cerebral infarct patients: A retrospective observational study." Medicine 102, no. 41 (2023): e35453. http://dx.doi.org/10.1097/md.0000000000035453.

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Less is known about the impact of heart failure (HF) and coronary artery disease (CAD) on motor recovery after cerebral infarction although previous studies have reported that preexisting HF and CAD were associated with increased mortality in stroke patients as well as unfavorable functional outcomes. In this study, we aimed to accurately evaluate the impact of HF and CAD on motor recovery after cerebral infarction by including only patients with corona radiata using diffusion tensor tractography. A total of 110 patients were recruited, and diffusion tensor tractography was performed within 7

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19

Woodford, Henry J., and Christopher Price. "Electromyographic Biofeedback for the Recovery of Motor Function After Stroke." Stroke 38, no. 6 (2007): 1999–2000. http://dx.doi.org/10.1161/strokeaha.107.482687.

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20

Kojović, Jovana, Nadica Miljković, Milica M. Janković, and Dejan B. Popović. "Recovery of motor function after stroke: A polymyography-based analysis." Journal of Neuroscience Methods 194, no. 2 (2011): 321–28. http://dx.doi.org/10.1016/j.jneumeth.2010.10.006.

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21

Formisano, R., P. Pantano, M. Ricci, P. Barbanti, R. Rossi, and G. L. Lenzi. "3-07-18 Late recovery of motor function after stroke." Journal of the Neurological Sciences 150 (September 1997): S146. http://dx.doi.org/10.1016/s0022-510x(97)85561-x.

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22

Veldema, Jitka, Kathrin Bösl, and Dennis Alexander Nowak. "Motor Recovery of the Affected Hand in Subacute Stroke Correlates with Changes of Contralesional Cortical Hand Motor Representation." Neural Plasticity 2017 (2017): 1–13. http://dx.doi.org/10.1155/2017/6171903.

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Objective. To investigate the relationship between changes of cortical hand motor representation and motor recovery of the affected hand in subacute stroke. Methods. 17 patients with motor impairment of the affected hand were enrolled in an in-patient neurological rehabilitation program. Hand motor function tests (Wolf Motor Function Test, Action Research Arm Test) and neurophysiological evaluations (resting motor threshold, motor evoked potentials, motor map area size, motor map area volume, and motor map area location) were obtained from both hands and hemispheres at baseline and two, four,

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Kraeutner, Sarah N., Cristina Rubino, Shie Rinat, et al. "Resting State Connectivity Is Modulated by Motor Learning in Individuals After Stroke." Neurorehabilitation and Neural Repair 35, no. 6 (2021): 513–24. http://dx.doi.org/10.1177/15459683211006713.

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Objective Activity patterns across brain regions that can be characterized at rest (ie, resting-state functional connectivity [rsFC]) are disrupted after stroke and linked to impairments in motor function. While changes in rsFC are associated with motor recovery, it is not clear how rsFC is modulated by skilled motor practice used to promote recovery. The current study examined how rsFC is modulated by skilled motor practice after stroke and how changes in rsFC are linked to motor learning. Methods Two groups of participants (individuals with stroke and age-matched controls) engaged in 4 weeks

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Sikuka, Hope Muwanei, Joseph Lupenga, and Loveness Nkhata. "Predictors of upper limb motor recovery in stroke survivors: a pre–post test study design." BMJ Open 14, no. 11 (2024): e081936. http://dx.doi.org/10.1136/bmjopen-2023-081936.

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ObjectivesThe study aimed to assess the predictors of upper limb motor recovery in stroke survivors.DesignPre–post test study design.SettingConducted in two centres (First Level Hospital and University Teaching Hospital in Lusaka).ParticipantsPatients living with stroke accessing physiotherapy services at the two public hospitals. A total of 52 patients were recruited at the start of the study, 6 were lost to follow-up and 46 completed the study.InterventionConventional physiotherapy for 8 weeks (5 September 2022–28 October 2022).Primary outcomeMotor function measured using a Fugl-Meyer assess

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Sun, Jing, Zheng Ke, Shea Ping Yip, Xiao-ling Hu, Xiao-xiang Zheng, and Kai-yu Tong. "Gradually Increased Training Intensity Benefits Rehabilitation Outcome after Stroke by BDNF Upregulation and Stress Suppression." BioMed Research International 2014 (2014): 1–8. http://dx.doi.org/10.1155/2014/925762.

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Physical training is necessary for effective rehabilitation in the early poststroke period. Animal studies commonly use fixed training intensity throughout rehabilitation and without adapting it to the animals' recovered motor ability. This study investigated the correlation between training intensity and rehabilitation efficacy by using a focal ischemic stroke rat model. Eighty male Sprague-Dawley rats were induced with middle cerebral artery occlusion/reperfusion surgery. Sixty rats with successful stroke were then randomly assigned into four groups: control (CG,n=15), low intensity (LG,n=15

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Lee, Jungsoo, Heegoo Kim, Jinuk Kim, Won Hyuk Chang, and Yun-Hee Kim. "Multimodal Imaging Biomarker-Based Model Using Stratification Strategies for Predicting Upper Extremity Motor Recovery in Severe Stroke Patients." Neurorehabilitation and Neural Repair 36, no. 3 (2021): 217–26. http://dx.doi.org/10.1177/15459683211070278.

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Background. Various prognostic biomarkers for upper extremity (UE) motor recovery after stroke have been reported. However, most have relatively low predictive accuracy in severe stroke patients. Objective. This study suggests an imaging biomarker-based model for effectively predicting UE recovery in severe stroke patients. Methods. Of 104 ischemic stroke patients screened, 42 with severe motor impairment were included. All patients underwent structural, diffusion, and functional magnetic resonance imaging at 2 weeks and underwent motor function assessments at 2 weeks and 3 months after stroke

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Tscherpel, Caroline, Sebastian Dern, Lukas Hensel, Ulf Ziemann, Gereon R. Fink, and Christian Grefkes. "Brain responsivity provides an individual readout for motor recovery after stroke." Brain 143, no. 6 (2020): 1873–88. http://dx.doi.org/10.1093/brain/awaa127.

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Abstract Promoting the recovery of motor function and optimizing rehabilitation strategies for stroke patients is closely associated with the challenge of individual prediction. To date, stroke research has identified critical pathophysiological neural underpinnings at the cellular level as well as with regard to network reorganization. However, in order to generate reliable readouts at the level of individual patients and thereby realize translation from bench to bedside, we are still in a need for innovative methods. The combined use of transcranial magnetic stimulation (TMS) and EEG has pro

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Nygren, Josefine, and Tadeusz Wieloch. "Enriched Environment Enhances Recovery of Motor Function after Focal Ischemia in Mice, and Downregulates the Transcription Factor NGFI-A." Journal of Cerebral Blood Flow & Metabolism 25, no. 12 (2005): 1625–33. http://dx.doi.org/10.1038/sj.jcbfm.9600157.

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The purpose of this study was to investigate the effect of enriched environment on motor function after experimental stroke in mice, and to determine whether time in enriched environment affects functional recovery. Earlier investigations have shown that rats placed in an enriched environment after focal ischemia, remarkably improve motor function, but similar observations in mice have not been reported. In this study, we show that placing mice in an enriched environment for 3 h daily for 2 weeks, after transient (50 mins) occlusion of the middle cerebral artery, enhanced neurologic outcome. C

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van Assche, Mitsouko, Elisabeth Dirren, Alexia Bourgeois, Andreas Kleinschmidt, Jonas Richiardi, and Emmanuel Carrera. "Periinfarct rewiring supports recovery after primary motor cortex stroke." Journal of Cerebral Blood Flow & Metabolism 41, no. 9 (2021): 2174–84. http://dx.doi.org/10.1177/0271678x211002968.

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After stroke restricted to the primary motor cortex (M1), it is uncertain whether network reorganization associated with recovery involves the periinfarct or more remote regions. We studied 16 patients with focal M1 stroke and hand paresis. Motor function and resting-state MRI functional connectivity (FC) were assessed at three time points: acute (<10 days), early subacute (3 weeks), and late subacute (3 months). FC correlates of recovery were investigated at three spatial scales, (i) ipsilesional non-infarcted M1, (ii) core motor network (M1, premotor cortex (PMC), supplementary motor area

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Li, Sheng. "Stroke Recovery Is a Journey: Prediction and Potentials of Motor Recovery after a Stroke from a Practical Perspective." Life 13, no. 10 (2023): 2061. http://dx.doi.org/10.3390/life13102061.

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Stroke recovery is a journey. Stroke survivors can face many consequences that may last the rest of their lives. Assessment of initial impairments allows reasonable prediction of biological spontaneous recovery at 3 to 6 months for a majority of survivors. In real-world clinical practice, stroke survivors continue to improve their motor function beyond the spontaneous recovery period, but management plans for maximal recovery are not well understood. A model within the international classification of functioning (ICF) theoretical framework is proposed to systematically identify opportunities a

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Wang, Xiaoting, Xiaoqin Huang, Mengqi Yang, et al. "Tongxinluo promotes axonal plasticity and functional recovery after stroke." Translational Neuroscience 11, no. 1 (2020): 428–38. http://dx.doi.org/10.1515/tnsci-2020-0127.

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AbstractBackgroundThe aim of this study was to investigate the neural plasticity in contralesional cortex and the effects of tongxinluo (TXL) in cerebral ischemic rats.MethodologyWe used stroke-prone renovascular hypertensive (RHRSP) cerebral ischemia rat models to study the effect of TXL and the underlying mechanisms. We performed foot-fault and beam-walking tests to evaluate the motor function of rats after cortical infarction. Biotinylated dextran amine (BDA) was used to track axonal sprouting and neural connections.ResultsTXL enhanced the recovery of motor function in cerebral infarction r

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Sanchez-Bezanilla, Sonia, N. David Åberg, Patricia Crock, et al. "Growth Hormone Promotes Motor Function after Experimental Stroke and Enhances Recovery-Promoting Mechanisms within the Peri-Infarct Area." International Journal of Molecular Sciences 21, no. 2 (2020): 606. http://dx.doi.org/10.3390/ijms21020606.

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Motor impairment is the most common and widely recognised clinical outcome after stroke. Current clinical practice in stroke rehabilitation focuses mainly on physical therapy, with no pharmacological intervention approved to facilitate functional recovery. Several studies have documented positive effects of growth hormone (GH) on cognitive function after stroke, but surprisingly, the effects on motor function remain unclear. In this study, photothrombotic occlusion targeting the motor and sensory cortex was induced in adult male mice. Two days post-stroke, mice were administered with recombina

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Turton, Ailie. "Mechanisms for Recovery of Hand and Arm Function after Stroke: A Review of Evidence from Studies Using Non-Invasive Investigative Techniques." British Journal of Occupational Therapy 61, no. 8 (1998): 359–64. http://dx.doi.org/10.1177/030802269806100804.

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The mechanisms for recovery of motor function after stroke are largely unknown. New non-invasive techniques of Positron Emission Tomography (PET) and Transcranial Magnetic Stimulation (TMS) have provided evidence for changes within the cortical motor areas and descending pathways after stroke in adult subjects. Reorganisation of the corticospinal tract originating from the damaged hemisphere is important for recovery of hand function. Some implications for occupational therapy are discussed.

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Platz, T., and P. Denzler. "Do psychological variables modify motor recovery among patients with mild arm paresis after stroke or traumatic brain injury who receive the Arm Ability Training?" Restorative Neurology and Neuroscience 20, no. 1-2 (2002): 37–49. https://doi.org/10.3233/rnn-2002-00213.

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{\it Purpose:} The Arm Ability Training improves motor function among stroke and traumatic brain injury patients with mild arm paresis. There is, however, a considerable variability in motor recovery among patients receiving the Arm Ability Training. The study investigated whether psychological variables can explain the variability in motor recovery. {\it Methods:} In a sample of 33 patients receiving the Arm Ability Training both motor performance (by use of the standardised arm function test TEMPA) and cognitive functions (attention, perceptual abilities, and learning) as well as depression

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Fregni, Felipe, and Alvaro Pascual-Leone. "Hand Motor Recovery After Stroke: Tuning the Orchestra to Improve Hand Motor Function." Cognitive and Behavioral Neurology 19, no. 1 (2006): 21–33. http://dx.doi.org/10.1097/00146965-200603000-00003.

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Boasquevisque, Danielle De S., Larissa Servinsckins, Joselisa P. Q. de Paiva, et al. "Contralesional Cathodal Transcranial Direct Current Stimulation Does Not Enhance Upper Limb Function in Subacute Stroke: A Pilot Randomized Clinical Trial." Neural Plasticity 2021 (August 10, 2021): 1–11. http://dx.doi.org/10.1155/2021/8858394.

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Transcranial direct current stimulation (tDCS) has the potential to improve upper limb motor outcomes after stroke. According to the assumption of interhemispheric inhibition, excessive inhibition from the motor cortex of the unaffected hemisphere to the motor cortex of the affected hemisphere may worsen upper limb motor recovery after stroke. We evaluated the effects of active cathodal tDCS of the primary motor cortex of the unaffected hemisphere (ctDCSM1UH) compared to sham, in subjects within 72 hours to 6 weeks post ischemic stroke. Cathodal tDCS was intended to inhibit the motor cortex of

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Tang, Jiaheng. "Effect of brain-computer interface training on functional recovery after stroke." Theoretical and Natural Science 21, no. 1 (2023): 75–79. http://dx.doi.org/10.54254/2753-8818/21/20230821.

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As the aging population continues to grow, the incidence of stroke is increasing yearly. Patients with stroke often have residual motor dysfunction symptoms, which seriously affects their life and work. The traditional treatment methods have limited applicability and efficacy, making it difficult for patients to control their muscles voluntarily and achieve cortical-muscle coupling. Brain-computer interface (BCI) technology can enable patients with severely impaired motor function to control external devices through brain-controlled movements, thus promoting the efficiency of motor rehabilitat

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Lin, Chen, Ahmed Babiker, Nina Srdanovic, Masha Kocherginsky, and Richard L. Harvey. "Depressive symptoms after stroke are associated with worse recovery." International Journal of Psychiatry in Medicine 55, no. 4 (2020): 227–38. http://dx.doi.org/10.1177/0091217420905459.

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Objective More studies are needed on how depressive symptoms in stroke patients can impact outcomes. We evaluated the relationship between depression symptom severity and motor outcomes in a cohort of patients with motor impairment from ischemic stroke. Method We enrolled consecutive ischemic stroke patients without a clinical diagnosis of depression who presented to a single-center urban academic referral hospital. The Patient Health Questionnaire-9 (PHQ-9) scale was used to measure depression symptom severity at three months. Three assessments of motor function were collected at stroke onset

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Trịnh, Thị Phương Lâm, Thị Thanh Bình Nguyễn, Thị Mỹ Lê та Công Tiến Nguyễn. "Mối tương quan giữa một số chỉ số trên cộng hưởng từ bó tháp trong tiên lượng khả năng phục hồi chức năng vận động ở bệnh nhân nhồi máu não vùng trên lều". Tạp chí thần kinh học Việt Nam, № 43 (6 листопада 2024): 46–52. http://dx.doi.org/10.62511/vjn.43.2024.038.

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Object: Correlation between some indices on pyramidal tract magnetic resonance in predicting motor function recovery in patients with supratentorial cerebral infarction. Method: Cross-sectional description with longitudinal follow-up includes 31 patients with supratentorial cerebral infarction within seven days and had an MRI at Bach Mai Hospital from January 2023 to December 2023. Result: The proportion of male patients with ischemic stroke predominated (61,3%). Hemiplegia was the most common symptom of ischemic stroke which damaged the path of the corticospinal tract. At three months after t

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Li, Rui, Jingyi Lu, Meiqi Wang, et al. "Ultrasound-Guided Median Nerve Electrical Stimulation to Promote Upper Limb Function Recovery after Stroke." Evidence-Based Complementary and Alternative Medicine 2022 (July 14, 2022): 1–10. http://dx.doi.org/10.1155/2022/3590057.

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Peripheral electrical nerve stimulation enhances hand function during stroke rehabilitation. Here, we proposed a percutaneous direct median nerve stimulation guided by ultrasound (ultrasound‐guided median nerve electrical stimulation, UG-MNES) and evaluated its feasibility and effectiveness in the treatment of stroke patients with upper limb extremity impairments. Sixty-three stroke patients (2-3 months of onset) were randomly divided into control and UG-MNES groups. Both groups received routine rehabilitation and the UG-MNES group received an additional ultrasound-guided electrical stimulatio

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Juan Du, Weihe Yao, Jianrui Li, et al. "Motor Network Reorganization After Repetitive Transcranial Magnetic Stimulation in Early Stroke Patients: A Resting State fMRI Study." Neurorehabilitation and Neural Repair 36, no. 1 (2021): 61–68. http://dx.doi.org/10.1177/15459683211054184.

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Objective To compare the effects of high-frequency (10 Hz) versus low-frequency (1 Hz) repetitive Transcranial Magnetic Stimulation (rTMS) on motor recovery and functional reorganization of the cortical motor network during the early phase of stroke. Methods Forty-six hospitalized, first-ever ischemic stroke patients in early stage (within two weeks) with upper limb motor deficits were recruited. They were randomly allocated to three groups with 10 Hz ipsilesional rTMS, 1 Hz contralesional rTMS, and sham rTMS of five daily session. All patients underwent motor function (Upper Extremity Fugl–Me

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STANESCU, Ioana C., Angelo C. BULBOACA, Gabriela B. DOGARU, Gabriel GUSETU, and Dana M. FODOR. "Predictors for early motor improvement in patients with ischemic stroke." Balneo Research Journal 10, Vol.10, No.3 (2019): 236–42. http://dx.doi.org/10.12680/balneo.2019.263.

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Disability as a stroke consequence is reported by 3% males and 2% females in general population. Motor deficits are common in stroke patients, but their complete recovery is seen only in a minority of cases. Assessment of motor deficits uses clinical methods, especially standardized scales, but also electrophysiological and imagistic methods. The motor recovery is a continuous process, maximal in the first month after stroke, decreasing gradually over the first 6 months. Most powerful predictors for motor recovery are clinical parameters: severity of motor deficit, onset of first voluntary mov

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Liauw, Jason, Stanley Hoang, Michael Choi, et al. "Thrombospondins 1 and 2 are Necessary for Synaptic Plasticity and Functional Recovery after Stroke." Journal of Cerebral Blood Flow & Metabolism 28, no. 10 (2008): 1722–32. http://dx.doi.org/10.1038/jcbfm.2008.65.

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Thrombospondins 1 and 2 (TSP-1/2) belong to a family of extracellular glycoproteins with angiostatic and synaptogenic properties. Although TSP-1/2 have been postulated to drive the resolution of postischemic angiogenesis, their role in synaptic and functional recovery is unknown. We investigated whether TSP-1/2 are necessary for synaptic and motor recovery after stroke. Focal ischemia was induced in 8- to 12-week-old wild-type (WT) and TSP-1/2 knockout (KO) mice by unilateral occlusion of the distal middle cerebral artery and the common carotid artery (CCA). Thrombospondins 1 and 2 increased a

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Shi, Liang-Feng, Chuan-Jie Wang, Ke-Wei Yu, Jun-Fa Wu, and Qi-Qi Zhang. "An Enriched Environment Promotes Motor Function through Neuroprotection after Cerebral Ischemia." BioMed Research International 2023 (February 8, 2023): 1–9. http://dx.doi.org/10.1155/2023/4143633.

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Stroke seriously affects human health. Many studies have shown that enriched environment (EE) can promote functional recovery after stroke, but the intrinsic mechanisms remain unclear. In order to study the internal mechanisms of EE involved in functional recovery after ischemic stroke and which mechanism plays a leading role in the recovery of limb function after cerebral infarction, key proteins potentially involved in neuronal protection and synaptic remodeling in the ischemic penumbra have been investigated. In this study, adult C57BL/6 mice after permanent middle cerebral artery occlusion

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Agius Anastasi, Andrei, Owen Falzon, Kenneth Camilleri, Malcolm Vella, and Richard Muscat. "Brain Symmetry Index in Healthy and Stroke Patients for Assessment and Prognosis." Stroke Research and Treatment 2017 (2017): 1–9. http://dx.doi.org/10.1155/2017/8276136.

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Objective.Quantitative neurophysiological signal parameters are of value in predicting motor recovery after stroke. The novel role of EEG-derived brain symmetry index for motor function prognostication in the subacute phase after stroke is explored.Methods. Ten male stroke patients and ten matched healthy controls were recruited. Motor function was first assessed clinically using the MRC score, its derivative Motricity Index, and the Fugl–Meyer assessment score. EEG was subsequently recorded first with subjects at rest and then during hand grasping motions, triggered by visual cues. Brain symm

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Christian Lukas, Denny, Williem Harvey, and Meilisa Sri Suzana. "The Effectiveness of Physical Exercise in Stroke Patient Recovery: A Systematic Review." International Journal of Health and Pharmaceutical (IJHP) 4, no. 4 (2024): 575–80. https://doi.org/10.51601/ijhp.v4i4.359.

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Background: Stroke is a leading cause of disability worldwide, significantly affecting motor function, mobility, and patients’ quality of life. Physical exercise is often recommended as part of rehabilitation programs to enhance recovery after a stroke. Objective: This study aims to systematically review the literature on the effectiveness of physical exercise in accelerating post-stroke recovery, particularly in improving motor function, mobility, and independence. Methods: A systematic search was conducted across electronic databases such as PubMed, Scopus, and ScienceDirect using keywords l

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van Nieuwenhuijzen, Petra S., Kim Parker, Vivian Liao, et al. "Targeting GABAC Receptors Improves Post-Stroke Motor Recovery." Brain Sciences 11, no. 3 (2021): 315. http://dx.doi.org/10.3390/brainsci11030315.

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Ischemic stroke remains a leading cause of disability worldwide, with limited treatment options available. This study investigates GABAC receptors as novel pharmacological targets for stroke recovery. The expression of ρ1 and ρ2 mRNA in mice were determined in peri-infarct tissue following photothrombotic motor cortex stroke. (R)-4-amino-cyclopent-1-enyl butylphosphinic acid (R)-4-ACPBPA and (S)-4-ACPBPA were assessed using 2-elecotrode voltage electrophysiology in Xenopus laevis oocytes. Stroke mice were treated for 4 weeks with either vehicle, the α5-selective negative allosteric modulator,

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DeBoer, Scott R., Robert Hubbard, Mahlet Mersha, Gabriel Pinilla Monsalve, Stefan Winter, and Steven R. Zeiler. "Enhanced Spontaneous Motor Recovery After Stroke in Mice Treated With Cerebrolysin." Neurorehabilitation and Neural Repair 35, no. 6 (2021): 525–33. http://dx.doi.org/10.1177/15459683211000734.

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Background Motor recovery after stroke in humans and in rodent models is time sensitive. Recovery in patients is a result of biological spontaneous recovery via endogenous repair mechanisms and is likely improved by enhancing the synaptic plasticity required for endogenous repair. Cerebrolysin is a polypeptide preparation known to enhance neuroplasticity and may improve recovery in patients. In mice, we tested the hypothesis that Cerebrolysin can act poststroke to enhance both spontaneous and training-associated motor recovery. Methods Mice were trained to perform a skilled prehension task. We

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NAKAMURA, RYUICHI, SANAE MORIYAMA, YOSHIAKI YAMADA, and KAZUNORI SEKI. "Recovery of Impaired Motor Function of the Upper Extremity after Stroke." Tohoku Journal of Experimental Medicine 168, no. 1 (1992): 11–20. http://dx.doi.org/10.1620/tjem.168.11.

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Cohen, L. "S32-1 Physiological substrates underlying recovery of motor function after stroke." Clinical Neurophysiology 121 (October 2010): S48. http://dx.doi.org/10.1016/s1388-2457(10)60202-7.

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