Academic literature on the topic 'Red blood cell (RBC) antibodies'

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Journal articles on the topic "Red blood cell (RBC) antibodies"

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Beerlage, Astrid, Joerg Halter, Sabine Gerull, et al. "Red Blood Cell Allo-Antibodies after Allogeneic Hematopoietic Stem Cell Transplantation." Blood 132, Supplement 1 (2018): 2551. http://dx.doi.org/10.1182/blood-2018-99-116237.

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Abstract Introduction Patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT) may require red blood cell (RBC) transfusions. AB0 blood group barrier is the clinically most important RBC group in transfusion medicine and HSCT and patients always receive AB0 compatible RBC transfusions. Some patients however develop allo-antibodies against minor RBC antigens. To date there is only limited information about the specificity, immuniser and risk factors for the development of RBC allo-antibodies. In this retrospective single centre study we aimed to identify specificities, risk
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Jajosky, Ryan, Connie Arthur, Jerry Allen, et al. "CD47 Regulates Red Blood Cell Alloimmunization in Mice." Blood 134, Supplement_1 (2019): 100. http://dx.doi.org/10.1182/blood-2019-131598.

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Background: Exposure to red blood cell (RBC) alloantigens during pregnancy or transfusion can lead to the development of alloantibodies and result in transfusion-related complications, including hemolytic transfusion reactions and hemolytic disease of the fetus and newborn. However, the factors that regulate RBC alloimmunization remain incompletely understood. Several studies suggest that alterations in factors that regulate RBC clearance may impact RBC uptake and antigen presentation, directly influencing the likelihood of RBC alloimmunization. To test this, we directly examined the potential
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Balbuena-Merle, Raisa, Ronald G. Hauser, Matthew Karafin, et al. "The Presence and Persistence of Pregnancy-Associated Red Blood Cell Alloantibodies in Blood Donors." Blood 134, Supplement_1 (2019): 2452. http://dx.doi.org/10.1182/blood-2019-121388.

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Background: Females have higher RBC alloantibody prevalence than males, presumably due to exposure to non-self RBC antigens through pregnancy as well as transfusion. Given the lack of routinely available and longitudinal data on lifelong pregnancy and transfusion histories, few studies have been able to distinguish pregnancy versus transfusion as contributing risk factors for RBC alloantibody induction or for the persistence of RBC alloantibody detectability. We hypothesized that pregnancy would be an important source of persistently detected RBC alloantibodies and investigated this in a longi
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Zabeida, Alexandra, Nancy Robitaille, Marc Lebel, and Christian Renaud. "Reevaluating Immunization Delays Post Red Blood Cell Transfusion." Paediatrics & Child Health 23, suppl_1 (2018): e58-e58. http://dx.doi.org/10.1093/pch/pxy054.147.

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Abstract BACKGROUND Current Canadian guidelines recommend to delay the measles, mumps, rubella (MMR) and varicella live attenuated vaccines by 6 months following transfusion of unwashed red blood cells (RBC) due to potential interference by serum antibodies. Thus, patients chronically transfused with RBC commonly suffer from a delay or absence of MMR and varicella vaccination. Over the last decades, not only has RBC handling changed, but also fewer blood donors have had natural mumps, measles and rubella infections, resulting in lower blood antibody levels. The recommendations may thus be unfo
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Maier, Cheryl L., Ryan Jajosky, Hans Verkerke, et al. "Storage Differentially Impacts Immunization to Red Cell Antigens." Blood 138, Supplement 1 (2021): 3239. http://dx.doi.org/10.1182/blood-2021-152670.

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Abstract Introduction: The impact of red blood cell (RBC) storage on alloimmunization rates after transfusion remains controversial, with clinical experience demonstrating conflicting results. Indeed, some reports suggest increased rates of alloimmunization associated with longer storage of RBC units, while others suggest no association between alloimmunization rates and length of storage. We hypothesized that this discrepancy may reflect the differential impact of storage on alloimmunization related to each unique antigen and the immune response elicited. Here we define the effect of red cell
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Quist, Erin, and Scott Koepsell. "Autoimmune Hemolytic Anemia and Red Blood Cell Autoantibodies." Archives of Pathology & Laboratory Medicine 139, no. 11 (2015): 1455–58. http://dx.doi.org/10.5858/arpa.2014-0337-rs.

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Autoimmune hemolytic anemia is a rare disorder caused by autoreactive red blood cell (RBC) antibodies that destroy RBCs. Although autoimmune hemolytic anemia is rare, RBC autoantibodies are encountered frequently and can complicate transfusion workups, impede RBC alloantibody identification, delay distribution of compatible units, have variable clinical significance that ranges from benign to life-threatening, and may signal an underlying disease or disorder. In this review, we discuss the common presenting features of RBC autoantibodies, laboratory findings, ancillary studies that help the pa
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Makarovska-Bojadzjieva, Tatjana, Emilija Velkova, and Milenka Blagoevska. "The Impact of Extended Typing On Red Blood Cell Alloimmunization in Transfused Patients." Open Access Macedonian Journal of Medical Sciences 5, no. 2 (2017): 107–11. http://dx.doi.org/10.3889/oamjms.2017.054.

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BACKGROUND: Red blood cell (RBC) alloimmunization is still an actual problem in our transfusion practice. In 2011, in addition to the regular ABO/D blood group typing, phenotyping for Rh (C, c, E, e) and Kell antigens was introduced for blood donors and patients undergoing blood transfusion. Our aim was to evaluate the impact of the extended RBC typing and donor/recipient matching on the incidence of RBC alloimmunization.METHODS: A retrospective comparative study was conducted by reviewing RBC request records for about 36,000 patients transfused with RBC in the period from 2013 to 2015 in comp
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Rofinda, Zelly Dia, and Yashinta Octavian Gita Setyanda. "Screening and Identification of Erythrocyte Antibodies: A Narrative Literature Review." Bioscientia Medicina : Journal of Biomedicine and Translational Research 8, no. 10 (2024): 5094–108. http://dx.doi.org/10.37275/bsm.v8i10.1091.

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Red blood cell (RBC) alloimmunization, the development of antibodies against foreign red blood cell antigens, is a critical concern in transfusion medicine. Alloantibodies can lead to adverse transfusion reactions, including hemolytic disease of the fetus and newborn (HDFN) and delayed hemolytic transfusion reactions (DHTR). This comprehensive literature review explores the intricacies of RBC alloimmunization, focusing on the screening and identification of erythrocyte antibodies. We delve into the prevalence and clinical significance of various alloantibodies, the underlying immunological mec
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Bendix, Brenda J., Eapen K. Jacob, Sara M. Barnes, et al. "Transfusion Reaction and Red Cell Antibody Formation in Allogeneic Hematopoietic Progenitor Cell Transplantation Recipients." Blood 126, no. 23 (2015): 3573. http://dx.doi.org/10.1182/blood.v126.23.3573.3573.

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Abstract Background: Little data exists on the incidence rate of transfusion reactions and red cell antibody formation following allogeneic (allo) hematopoietic progenitor cell transplant (HPCT) recipients. Study Design and Methods: Consecutive related and unrelated Allogeneic HPCTs from 2006 to 2013 were retrospectively reviewed regardless of graft source. Allo HPCT recipients were analyzed as a whole as well as divided into ABO compatibility groups of identical, minor mismatch, and major/bidirectional mismatch. Transfusions, transfusion reactions and antibodies were analyzed for the first ye
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Chapuy, Claudia I., Richard M. Kaufman, Edwin P. Alyea, and Jean M. Connors. "Daratumumab for Delayed Red Cell Engraftment after Hematopoietic Stem Cell Transplant." Blood 132, Supplement 1 (2018): 2545. http://dx.doi.org/10.1182/blood-2018-99-111880.

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Abstract Allogeneic stem cell transplantation represents a curative treatment option for patients with malignant hematologic diseases, including myelodysplastic syndrome (MDS). In 25-50% of transplants, HLA-matched allogeneic stem cell donors have some degree of ABO incompatibility with the recipient. Major ABO incompatibility is caused by recipient antibodies directed against donor red blood cells (RBCs) and may lead to delayed RBC recovery and transient pure red cell aplasia (PRCA). We describe a case of treatment-refractory pure red cell aplasia following a major ABO-mismatchedallogeneic st
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Dissertations / Theses on the topic "Red blood cell (RBC) antibodies"

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Jadidi, Mansoor. "Numerical and Experimental Model of Healthy and Damaged Red Blood Cell Trajectories in Micro-channels." Thesis, Griffith University, 2023. http://hdl.handle.net/10072/421347.

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Motivation: Red blood cells (RBCs) are the most common cells in the blood due to their high concentration. The RBC has a deformable membrane enclosing a jelly-like fluid known as the cytosol. For many years, the dynamics of RBCs has attracted growing interest both numerically and experimentally in various fields of research on biological systems. Owing to their high deformability, RBCs exhibit complex dynamic behaviours in micro-vessels where Reynolds numbers (Re) are less than unity (Re < 1). First, a healthy RBC at a low shear rate or a high viscosity contrast (λ - defined as the ratio of vi
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Han, Tian. "Flow cell separation in fluctuating g-field." Thesis, Brunel University, 2015. http://bura.brunel.ac.uk/handle/2438/11105.

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Field flow fractionation of particles in rotating coiled column has been investigated in recent year. In contrast to the classical mode of field flow fractionation in narrow channels, the use of rotating coiled columns offers the possibility of large sample loading. In this thesis, the potential for new cell separation methods based on the use of flow fractionation in fluctuating g-fields generated in rotating coil columns is examined. The effects of operational conditions (flow rate and rotational speed – Chapter 3 and Chapter 5); cell properties (cell flexibility – Chapter 4); and column sha
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Ji, Yu. "Characterisation of red blood cell Phagocytosis and assessment of nanoparticle uptake by Monocytic cells." Thesis, Queensland University of Technology, 2021. https://eprints.qut.edu.au/208148/1/Yu_Ji_Thesis.pdf.

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This thesis explored interactions between monocytes and IgG sensitised RBCs as well as synthetic particles for clinical and biomedical application. A monocyte monolayer assay was developed for Red Cell Reference Laboratory in Australia to predict transfusion outcomes, and mechanism and immune modulation associated with this assay and biomedical potential of polystyrene particles were explored using genetic and biological studies. The results obtained will contribute to improved transfusion safety and patient management and contribute knowledge in the fields of biomedical research using nanomat
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Poole, Geoffrey D. "The production of soluble proteins having blood group activity, and their use in quantifying red cell antibodies in pregnant women." Thesis, University of Portsmouth, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.500335.

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Haemolytic disease of the fetus and newborn is caused by the placental transfer of maternal IgG antibodies that are directed against fetal red (blood) cell antigens. Fetal spleen mononuclear cells phagocytose IgG coated red cells, removing them from the fetal circulation and causing anaemia and, if untreated, hydrops fetalis and kernicterus, both of which may be severe and occasionally fatal. It has been suggested that some antibodies, anti-K in particular, cause fetal anaemia predominantly through suppression of erythropoiesis rather than through red cell destruction. Antenatal screening for
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Alves, Eloisa Nunes. "Red blood cell (RBC) - Teste de hemolise: uma alternativa ao teste de Draize-irritacao ocular na avaliacao do poder toxico de produtos cosmeticos no controle de qualidade." Rio de Janeiro : [s.n.], 2003. http://bvssp.cict.fiocruz.br/lildbi/docsonline/get.php?id=221.

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Alves, Eloisa Nunes. "Red blood cell (RBC) - Teste de hemólise: uma alternativa ao teste de Draize-irritação ocular na avaliação do poder tóxico de produtos cosméticos no controle de qualidade." reponame:Repositório Institucional da FIOCRUZ, 2003. https://www.arca.fiocruz.br/handle/icict/8442.

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Made available in DSpace on 2014-09-24T12:58:32Z (GMT). No. of bitstreams: 2 license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) 170.pdf: 2427185 bytes, checksum: 0bf00a5fbc2821c8dcd7fdd3a2524593 (MD5) Previous issue date: 2003<br>O objetivo do presente trabalho, foi o de correlacionar os resultados obtidos em Teste convencional in vivo, de Draize de Irritação ocular, em coelhos, que preconiza o estudo quantitativo das lesões induzidas por produtos cosmétidos na conjuntiva, córnea e íris, com os resultados do Teste RBC, in vitro, que preconiza a análise quantitativa da
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Ferreira, Angela Melgaço. "Avaliação da estabilidade de anticorpos anti-eritrocitários irregulares em amostras biológicas para produção de controles internos em laboratórios de imuno-hematologia." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/17/17155/tde-07062017-142345/.

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O uso de amostras \"Controle Interno\" (CI) para validação de técnicas e reagentes imunohematológicos é exigido por lei e indispensável para identificar erros nos processos laboratoriais. No Brasil, as legislações que regem a hemoterapia aprovam a produção dos reagentes CI pelos serviços de hemoterapia (SH), desde que o processo seja previamente validado e tenha critérios de aceitação bem definidos. O estudo analisou a estabilidade de anticorpos anti-eritrocitários irregulares, da classe IgG, presentes nos plasma fresco congelado (PFC) de doadores e nas amostras pré-transfusionais de pacientes
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Meirelles, Alyne Fávero Galvão. "Uso da cromatografia líquida de alta eficiência acoplada à espectrometria de massas sequencial para determinação do perfil de eicosanoides em plasma após estimulação: comparação entre pacientes com anemia falciforme e indivíduos saudáveis." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/60/60135/tde-02052016-105840/.

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Os eicosanoides, produtos do metabolismo do ácido araquidônico, apresentam papel importante na homeostasia e na patogênese de diversas doenças humanas. A biossíntese desses compostos pode ser estimulada por agentes farmacológicos como ionóforos e inibidores da Ca2+-ATPase, e também por agonistas naturais como o formil-metionil-leucil-fenialanina (fMLP). Considerando os interesses em avaliar e comparar o perfil de mediadores lipídicos, como os leucotrienos (LTs), as prostaglandinas (PGs), os ácidos epoxieicosatrienoicos (EETs), os ácidos dihidroxitetraenoicos (DiHETEs) e os ácidos hidroxieicosa
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Janvier, Florence. "Preparation, characterization, and rheological properties of star-shaped poly(ethylene glycol) with a cholane core and study of its effect on red blood cell aggregation." Thèse, 2009. http://hdl.handle.net/1866/7822.

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Books on the topic "Red blood cell (RBC) antibodies"

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George, Garratty, and American Association of Blood Banks. Meeting, eds. Red cell antigens and antibodies. American Association of Blood Banks, 1986.

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Madden, John Eugene. Evaluation of the polyethylene glycol anti globulin test for detection of red blood cell antibodies and incorporation into microtitre plate technology. The Author], 1994.

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Monoclonal antibodies against human red blood cell and related antigens. Arnette, 1988.

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Raine, Tim, James Dawson, Stephan Sanders, and Simon Eccles. Haematology. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199683819.003.0013.

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AnaemiaTransfusion of blood productsClotting emergenciesBleedingAnticoagulationReduced red blood cell (RBC) mass, usually conveniently approximated as reduced haemoglobin concentration (eg ♂ &lt;130g/L, ♀ &lt;115g/L1). Causes easily divide into 3 basic mechanisms (reduced RBC production, increased RBC des-truction, RBC loss) with clues found in abnormalities of RBC size and shape....
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Noris, Marina, and Tim Goodship. The patient with haemolytic uraemic syndrome/thrombotic thrombocytopenic purpura. Edited by Giuseppe Remuzzi. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0174.

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The patient who presents with microangiopathic haemolytic anaemia, thrombocytopenia, and evidence of acute kidney injury presents a diagnostic and management challenge. Haemolytic uraemic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP) are two of the conditions that frequently present with this triad. They are characterized by low platelet count with normal or near-normal coagulation tests, anaemia, and signs of intravascular red cell fragmentation on blood films, and high LDH levels.HUS associated with shiga-like toxins produced usually by E.coli (typically O157 strains) may occu
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Macdougall, Iain C. Erythropoiesis-stimulating agents in chronic kidney disease. Edited by David J. Goldsmith. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0124.

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The advent of recombinant human erythropoietin (epoetin) in the late 1980s transformed the management of renal anaemia, liberating many dialysis patients from lifelong regular blood transfusions, in turn causing severe iron overload and human leucocyte antigen sensitization. Epoetin can be administered either intravenously or subcutaneously, but the half-life of the drug is fairly short at around 6–8 hours, necessitating frequent injections. To circumvent this problem, two manipulations to the erythropoietin molecule were engineered. The first of these was to attach an extra two carbohydrate c
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Book chapters on the topic "Red blood cell (RBC) antibodies"

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Kim, Cheorl-Ho. "Human Red Blood Cell (RBC) Blood Groups System." In Glycoimmunology in Xenotransplantation. Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-99-7691-1_6.

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Frey, Beat M., and Marion E. Reid. "Clinical and Laboratory Impact of Blood Group Antigens and Antibodies." In Red Cell Transfusion. Humana Press, 1998. http://dx.doi.org/10.1007/978-1-4612-1798-5_14.

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Soni, Kapil Dev, and Rahul Chaurasia. "How to Use Blood and Blood Products." In Rational Use of Intravenous Fluids in Critically Ill Patients. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-42205-8_12.

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AbstractThis chapter discusses the available evidence for blood transfusions in various subgroups of critically ill patients and other common issues pertaining to the transfusion of blood and blood components in the ICU. While blood and blood products can a be lifesaving therapy, the decision to transfuse should be based on individual factors, and the risk–benefit ratio of adverse events should be considered. Restrictive red blood cell (RBC) transfusion strategies are generally more beneficial, and platelet transfusions should be administered after risk assessment for bleeding, cause and patte
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�lvarez, F. V., R. Alonso, A. Paz, J. H. Ladenson, and B. Prieto. "Nucleated Red Blood Cell Recovery from Maternal Blood with Non-Commercial Monoclonal Antibodies." In Fetal Cells and Fetal DNA in Maternal Blood. KARGER, 2001. http://dx.doi.org/10.1159/000062519.

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Strasser, E., B. Neidhardt, P. Klein, et al. "Life-Threatening Hemorrhage in a Patient with Red Cell Antibodies — Effective Blood Coagulation with rFVIIa." In 32nd Hemophilia Symposium Hamburg 2001. Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/978-3-642-18150-4_27.

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Ali Jalali Far, Mohammad, and Zeinab Eftekhar. "Red Blood Cell Alloimmunization: Life-Threatening Response." In Blood Groups - New Perspectives [Working Title]. IntechOpen, 2024. http://dx.doi.org/10.5772/intechopen.1003885.

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Alloimmunization is the formation of antibodies against non-self-antigens from a different member of the same species due to exposure to them via transfusion, pregnancy, or transplantation. Further to ABO(H) alloantigens, more alloantibody reactivity toward RBCs appeared as a result of transfusion evolution. Considering that nowadays RBC polymorphisms include more than 300 distinct alloantigens, alloantibodies produced against these antigens can cause various complications such as hemolytic disease of the fetus and newborn (HDFN) or hemolytic transfusion reactions (HTRs) which are related to s
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Needs, Malcolm. "Immune-Mediated Red Cell Destruction." In Transfusion and Transplantation Science. Oxford University Press, 2018. http://dx.doi.org/10.1093/hesc/9780198735731.003.0008.

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This chapter shows how and why red blood cells (RBCs) are destroyed in the body, in vivo, by antibodies. It first describes the difference between intravascular and extravascular haemolysis. The chapter then defines the role of antibodies and complement in red cell destruction. It outlines the clinical significance of red cell antibodies and the use of the direct antiglobulin test (DAT). The chapter then shifts to detail the causes of haemolytic transfusion reactions, and the types of autoimmune haemolytic anaemias and the problems associated with finding compatible blood. Finally, the chapter
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"Red Blood Cell (RBC) Count." In Clinical Veterinary Advisor. Elsevier, 2013. http://dx.doi.org/10.1016/b978-1-4160-3969-3.00373-5.

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Park, Minseon, and Yoon Hwan Chang. "Clinical Significance of Red Blood Cell Indices." In Red Blood Cells - Functions and Significance [Working Title]. IntechOpen, 2025. https://doi.org/10.5772/intechopen.1008323.

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Red blood cell (RBC) indices not only assess anemia but also play a crucial role in predicting and evaluating significant health issues, such as cardiovascular morbidity and mortality from cancer, cardiovascular disease, and infection. Ongoing research is expected to further elucidate these associations. Factors associated with RBC indices and red blood cell distribution width (RDW) beyond the normal range include nutritional imbalances, underlying chronic disease conditions, oxidative stress, chronic inflammation, and insulin resistance. Compared to studies related to outcomes, research on fa
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Mahajan, Aarti. "Estimation of Red Blood Cell (RBC) Count." In Objective Structured Practical Examination in Physiology. Jaypee Brothers Medical Publishers (P) Ltd., 2010. http://dx.doi.org/10.5005/jp/books/11053_6.

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Conference papers on the topic "Red blood cell (RBC) antibodies"

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Pamungkas, Yuri, Edwin Nugroho Njoto, Dwinka Syafira Eljatin, Intan Fitri Hardyanti, Tazkiya Umamah, and Kartika Jilan Putri. "Implementation of EfficientNet-B0 Architecture in Malaria Detection System Based on Patient Red Blood Cell (RBC) Images." In 2024 International Conference on Information Technology Research and Innovation (ICITRI). IEEE, 2024. http://dx.doi.org/10.1109/icitri62858.2024.10699220.

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Zhu, Cheng, and Scott E. Chesla. "Dissociation of Individual Molecular Bonds Under Force." In ASME 1997 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1997. http://dx.doi.org/10.1115/imece1997-0286.

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Abstract Specific interactions between receptors on cell surfaces are essential for living organisms to sense and adapt to their environment. For example, CD16A (Feγ receptor IIIA) signals a variety of immune functions upon binding of immunoglobulin (Ig) G. While receptor-ligand binding has been extensively studied in chemical terms, only until very recently has direct measurement of individual bond forces become possible. Evans et al. [1] pioneered the use of the micropipet technique to measure detachment forces between two red blood cells (RBC) crosslinked by antibodies. While these authors
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Mueller-Eckhardt, C. "A SURVEY OF THE CLINICAL EFFICACY OF RETICULOENDOTHELIAL BLOCKADE EMPHASIZING INTRAVENOUS IgG AND ANTI-RH(D) GLOBULIN." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644760.

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"Blockade" of the RES is the maj0or therapeutic principle in autoimmune thrombocytopenic purpura (AITP) and related conditions. It can be accomplished by a number of possibilities which include, first, removal of the main sequestration site of antibody-sensitized platelets (i.e. splenectomy), or, second, functional "modulation" of the phagocytic capacity of the RES. The latter is achieved by either "unspecific" or "specific" means. "Unspecific" means are defined as being operative via a mechanism in which apparantly no immunological reactants are involved, while "specific" means comprise the d
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van der Burgt, René C. H., Patrick D. Anderson, and Frans N. van de Vosse. "Probing Red Blood Cell Dynamics." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80255.

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Because of the high volume contents of red blood cells (RBCs) in blood, mechanics of a single RBC plays a large role in the rheological description of blood. Moreover, RBC dynamics drive plasma mixing and lateral transport of its components, which are both involved in blood coagulation. Therefore, a characterization of the dynamical parameters of RBCs under different flow conditions is needed. Experimental methods, like pipette aspiration or optical trapping, seem to be unable to accurately capture RBC dynamics, due to contact of a solid with the cell membrane. Especially at larger deformation
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Kumar, Anurag, Toru Yamada, and Mohammad Faghri. "Multi-Scale Particle Simulation of Red Blood Cell in Microcirculation." In ASME 2010 8th International Conference on Nanochannels, Microchannels, and Minichannels collocated with 3rd Joint US-European Fluids Engineering Summer Meeting. ASMEDC, 2010. http://dx.doi.org/10.1115/fedsm-icnmm2010-31080.

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The complex rheology of red blood cell (RBC) in microcirculation has been a topic of interest for many decades. As RBC is highly deformable, shape change affects the microcirculation and such effect should be accounted accurately to understand the rheology of blood flow. A particle based model is developed to construct the red blood cell (RBC) based on the minimum energy principle. A bead-spring network is utilized to represent the cross-sectional plane of RBC membrane. The total energy of the RBC is associated with spring stretch/compression, bending and constraint of fixed area. Shape optimi
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Santos, M. T., J. Aznar, J. Valles, and J. L. Perez-Reguejo. "ASPIRIN MODIFIES RED BLOOD CELL BEHAVIOUR (RBC) IN THE PLATELET-RBC INTERACTION." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644821.

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RBC stimulate the initial stages of platelet activation by collagen as evaluated by the BASIC wave (Perez-Requejo et al. Thromb Haemostas 54:799 1985). In order to get some insight into the mechanisms of platelet-RBC interactions, a BASIC wave was induced by lug/ml of collagen after mixing "in vitro" platelets and RBC obtained both before and two hours after a single dose of 500 mg of ASA from normal subjects. The TXB2 formed was also evaluated. The results show (Table) that non aspirinized RBC (non-ASA-RBC) increase the BASIC wave intensity of aspirinized platelets (ASA-PRP) by a cyclooxygena
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AlMomani, T. D., S. C. Vigmostad, H. S. Udaykumar, and K. B. Chandran. "Modeling of Red Blood Cell Dynamics Using Fluid Structure Interaction (FSI) Technique." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19039.

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Red blood cells (RBCs) or erythrocytes are biconcave disks with diameter of 8μm and thickness of 2 μm. RBC can be considered as a nucleus free deformable capsule enclosed by a flexible membrane and consisting of an incompressible viscous fluid [8, 9]. The deformation of RBCs is thought to play a major role in both RBC dynamics and functionality. Previous studies have indicated that two important characteristics related to deformation of the RBC [1]: i) the interior of the RBC is a liquid state that surrounded by an elastic membrane, ii) the biconcave shape of the RBC enables it to deform into
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Tatsumi, Kazuya, Ryo Kuroki, Kosuke Nishitani, Tomoki Arakawa, and Kazuyoshi Nakabe. "Numerical Modeling of Red Blood Cell Suspended in a Channel With Uniform Magnetic Field." In ASME-JSME-KSME 2011 Joint Fluids Engineering Conference. ASMEDC, 2011. http://dx.doi.org/10.1115/ajk2011-36032.

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Numerical simulations were carried out for the red blood cell (RBC) suspended in a stationary fluid. Elastic spring model were used to calculate the RBC membrane, and finite volume method was used to solve the flow field. The magnetic effect on the RBC was model by considering the anisotropic diamagnetic susceptibility of the phospholipids and transmembrane protein. The torque produced by these components at each element edge of the mesh generated on the cell surface was first calculated, and then the force applied to each node was evaluated. Experimental measurement of the RBC behavior in mic
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Hysi, Eno, Ratan K. Saha, Min Rui, and Michael C. Kolios. "Detection and characterization of red blood cell (RBC) aggregation with photoacoustics." In SPIE BiOS, edited by Alexander A. Oraevsky and Lihong V. Wang. SPIE, 2012. http://dx.doi.org/10.1117/12.908685.

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Firoozbakhsh, K., M. T. Ahmadian, and M. Hasanian. "Simulation of Red Blood Cell Passing Through Constrictions Using Modified Moving Particle Semi-Implicit Method." In ASME 2011 International Mechanical Engineering Congress and Exposition. ASMEDC, 2011. http://dx.doi.org/10.1115/imece2011-63535.

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During the circulation of RBC it undergoes elastic deformation as it passes through micro-capillaries where the inner diameter of the constriction can be about 3 micro meters. It means RBC shape must be changed in order to pass through these narrow channels. The role of mechanical behavior of RBC and the deformability traits of RBC are observed with the several experimental studies [1]. Several methods were implemented to simulate the mechanical behavior of RBCs in micro-capillaries [1, 2]. One of the most recent methods is Moving Particle Semi-implicit method (MPS) which is a Lagrangian metho
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Reports on the topic "Red blood cell (RBC) antibodies"

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Spiegel, Yitzhak, Michael McClure, Itzhak Kahane, and B. M. Zuckerman. Characterization of the Phytophagous Nematode Surface Coat to Provide New Strategies for Biocontrol. United States Department of Agriculture, 1995. http://dx.doi.org/10.32747/1995.7613015.bard.

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Chemical composition and biological role of the surface coat (SC) of the root-knot nematodes, Meloidogyne spp. are described. SC proteins of M. incognita race 3 infective juveniles (J2) were characterized by electrophoresis and western blotting of extracts from radioiodine and biotin-labelled nematodes. J2 labelled with radioiodine and biotin released 125I and biotin-labelled molecules into water after 20 hours incubation, indicating that SC proteins may be loosely attached to the nematode. Antiserum to the principal protein reacted with the surface of live J2 and with surface proteins previou
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