Relevant bibliographies by topics / Reduction (Chemistry) Toxicity testing

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Reduction (Chemistry) Toxicity testing'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 February 2022

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Journal articles on the topic "Reduction (Chemistry) Toxicity testing"

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Bhanushali, M., V. Bagale, A. Shirode, Y. Joshi, and V. Kadam. "An in-vitro toxicity testing - a reliable alternative to toxicity testing by reduction, replacement and refinement of animals." International Journal of Advances in Pharmaceutical Sciences 1, no. 1 (2010): 15–31. http://dx.doi.org/10.5138/ijaps.2010.0976.1055.01002.

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Ferreira, Mónica V., Wilhelm Jahnen-Dechent, and Sabine Neuss. "Standardization of Automated Cell-Based Protocols for Toxicity Testing of Biomaterials." Journal of Biomolecular Screening 16, no. 6 (2011): 647–54. http://dx.doi.org/10.1177/1087057111405380.

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Advances in high-throughput screening (HTS) instrumentation have led to enormous reduction of costs (e.g., of pipetting stations) and to the development of smaller instruments for automation of day-to-day routines in small research laboratories. In the biomaterials community, there has been an increasing interest for standardized screening protocols to identify cell type–specific cytocompatible biomaterials suitable for tissue engineering (TE) applications. In this study, the authors established a multiplexed assay protocol for toxicity screening of biomaterials using a low- to medium-throughp
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Yankova, I., E. Ivanova, K. Todorova, et al. "Assessment of the toxicity and antiproliferative activity of hemocyanins from Helix lucorum, Helix aspersa and Rapana venosa." Bulgarian Chemical Communications Volume 53, Special Issue A (2021): 15–21. http://dx.doi.org/10.34049//bcc.53.a.0003.

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Hemocyanins (Hcs) are respiratory, oxygen-carrying metalloproteins that are freely dissolved in the hemolymph of many molluscs and arthropods. The interest in hemocyanins has grown significantly since it was found that they can be successfully used in immunotherapy of neoplastic diseases as non-specific or active stimulators of the immune system. The present study aims to assess the cytotoxicity, in vivo toxicity and antiproliferative activity of hemocyanins isolated from marine snail Rapana venosa (RvH), garden snails Helix lucorum (HlH) and Helix aspersa (HaH). For in vitro safety testing, 3
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Balogun, Fatai Oladunni, and Anofi Omotayo Tom Ashafa. "Acute and Subchronic Oral Toxicity Evaluation of Aqueous Root Extract ofDicoma anomalaSond. in Wistar Rats." Evidence-Based Complementary and Alternative Medicine 2016 (2016): 1–11. http://dx.doi.org/10.1155/2016/3509323.

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The present study evaluated the safety of aqueous root extract ofDicoma anomala(AQRED) through acute and subchronic toxicity studies. Single oral dose of AQRED at the concentration of 0, 5, 300, and 2000 mg/kg as well as 125, 250, and 500 mg/kg/day was administered to rats for 14-day acute and 90-day subchronic oral toxicity studies. The results revealed no mortalities or observed clinical signs of toxicity in all the rats during both investigation periods. In subchronic toxicity testing, administration of AQRED also did not cause any changes in body weight as well as food and water consumptio
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Zavisic, Gordana, Sasa Petricevic, Slavica Ristic, et al. "Probiotic potential of Lactobacillus fermentum G-4 originating from the meconium of newborns." Journal of the Serbian Chemical Society 84, no. 4 (2019): 365–76. http://dx.doi.org/10.2298/jsc181105015z.

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The present study was dedicated to determining probiotic potential of a human isolate G-4, originated from meconium. The isolate was identified using morphological, physiological and biochemical assays and molecular method based on 16S rRNA gene sequencing. In order to evaluate its probiotic properties in vitro tests were performed: the survival in simulated gastrointestinal conditions, adhesion to hexadecane, and antimicrobial activity. Safety aspects of the isolate were examined by testing toxicity, gastrointestinal tolerance and bacterial translocation in vivo, as well as hemolytic activity
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Huang, Hung-Jin, Yu-Hsuan Lee, Yung-Ho Hsu, Chia-Te Liao, Yuh-Feng Lin, and Hui-Wen Chiu. "Current Strategies in Assessment of Nanotoxicity: Alternatives to In Vivo Animal Testing." International Journal of Molecular Sciences 22, no. 8 (2021): 4216. http://dx.doi.org/10.3390/ijms22084216.

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Millions of experimental animals are widely used in the assessment of toxicological or biological effects of manufactured nanomaterials in medical technology. However, the animal consciousness has increased and become an issue for debate in recent years. Currently, the principle of the 3Rs (i.e., reduction, refinement, and replacement) is applied to ensure the more ethical application of humane animal research. In order to avoid unethical procedures, the strategy of alternatives to animal testing has been employed to overcome the drawbacks of animal experiments. This article provides current a
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Scognamiglio, Valentina, Dario Di Giuseppe, Magdalena Lassinantti Gualtieri, Laura Tomassetti, and Alessandro F. Gualtieri. "A Systematic Study of the Cryogenic Milling of Chrysotile Asbestos." Applied Sciences 11, no. 11 (2021): 4826. http://dx.doi.org/10.3390/app11114826.

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For more than 40 years, intensive research has been devoted to shedding light on the mechanisms of asbestos toxicity. Given the key role of fibre length in the mechanisms of asbestos toxicity, much work has been devoted to finding suitable comminution routes to produce fibres in desired size intervals. A promising method is cryogenic milling that, unlike other mechanical size reduction techniques, preserves the crystal–chemical properties of materials. In this study, the effect of cryogenic milling on the physical–chemical properties of commercial Russian chrysotile was studied in order to pro
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Jonitz-Heincke, Anika, Jenny Tillmann, Melanie Ostermann, et al. "Label-Free Monitoring of Uptake and Toxicity of Endoprosthetic Wear Particles in Human Cell Cultures." International Journal of Molecular Sciences 19, no. 11 (2018): 3486. http://dx.doi.org/10.3390/ijms19113486.

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The evaluation of the biological effects of endoprosthetic wear particles on cells in vitro relies on a variety of test assays. However, most of these methods are susceptible to particle-induced interferences; therefore, label-free testing approaches emerge as more reliable alternatives. In this study, impedance-based real-time monitoring of cellular viability and metabolic activity were performed following exposure to metallic and ceramic wear particles. Moreover, label-free imaging of particle-exposed cells was done by high-resolution darkfield microscopy (HR-ODM) and field emission scanning
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Westlund, Karin N., та Morgan Zhang. "Building and Testing PPARγ Therapeutic ELB00824 with an Improved Therapeutic Window for Neuropathic Pain". Molecules 25, № 5 (2020): 1120. http://dx.doi.org/10.3390/molecules25051120.

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Effective, non-addictive therapeutics for chronic pain remain a critical need. While there are several potential therapeutics that stimulate anti-inflammatory mechanisms to restore homeostasis in the spinal dorsal horn microenvironment, the effectiveness of drugs for neuropathic pain are still inadequate. The convergence of increasing knowledge about the multi-factorial mechanisms underlying neuropathic pain and the mechanisms of drug action from preclinical studies are providing the ability to create pharmaceuticals with better clinical effectiveness. By targeting and activating the peroxisom
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Handral, Harish K., C. Ashajyothi, Gopu Sriram, Chandrakanth R. Kelmani, Nileshkumar Dubey, and Tong Cao. "Cytotoxicity and Genotoxicity of Metal Oxide Nanoparticles in Human Pluripotent Stem Cell-Derived Fibroblasts." Coatings 11, no. 1 (2021): 107. http://dx.doi.org/10.3390/coatings11010107.

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Advances in the use of nanoparticles (NPs) has created promising progress in biotechnology and consumer-care based industry. This has created an increasing need for testing their safety and toxicity profiles. Hence, efforts to understand the cellular responses towards nanomaterials are needed. However, current methods using animal and cancer-derived cell lines raise questions on physiological relevance. In this aspect, in the current study, we investigated the use of pluripotent human embryonic stem cell- (hESCs) derived fibroblasts (hESC-Fib) as a closer representative of the in vivo response
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Dissertations / Theses on the topic "Reduction (Chemistry) Toxicity testing"

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Oluwadare, Eyitayo Olufemi. "Development of a Caenorhabditis elegans model for the assessment of toxicity and its application in testing novel anthelmintics." Thesis, Edinburgh Napier University, 2017. http://researchrepository.napier.ac.uk/Output/1036075.

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The nematode Caenorhabditis elegans is an alternative model used in biomedical research for the investigation of descriptive and mechanistic toxicity assessment of chemicals. There are considerable differences in published data, especially in terms of reproducibility and validation of toxicity endpoints, and the techniques used in the investigation of these endpoints. This thesis describes the evaluation of toxicological endpoints following the exposure of C. elegans to chemicals which include; zinc oxide nanoparticles (ZnONP), Diethylstilbestrol (DES) and derivatized target-specific anthelmin
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Olivier, Julie A. "Chemical characterization and aquatic biotoxicity testing of dye wastewaters and their reduction products." Thesis, This resource online, 1993. http://scholar.lib.vt.edu/theses/available/etd-08182009-040505/.

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Ard, Teri A. "The comparative toxicities of filtrates from conventional and alternative bleaching agents." Diss., Georgia Institute of Technology, 1996. http://hdl.handle.net/1853/7008.

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Chissini, Carina Rejane Carvalho. "Adequação de parâmetros físicos e químicos de efluente industrial e relação com a toxicidade." reponame:Repositório Institucional da UCS, 2015. https://repositorio.ucs.br/handle/11338/1042.

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A identificação dos possíveis parâmetros determinantes da toxicidade em efluente industrial buscando a redução da carga poluidora auxilia na minimização dos efeitos tóxicos decorrentes do lançamento de efluente industrial em um corpo receptor de forma a preservar a biota aquática. O objetivo deste estudo foi adequar os parâmetros físicos e químicos e o fator de toxicidade à legislação ambiental.O estudo foi dividido em três etapas realizadas ao longo de outubro de 2010 a fevereiro de 2015. A Etapa 1 incluiu as análises físicas, químicas e toxicológicas de amostras coletadas no período entre ou
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Derache, Philippe. "Influence de la reduction des xenobiotiques organo-nitres sur la peroxydation des phospholipides." Toulouse 3, 1986. http://www.theses.fr/1986TOU30062.

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Introduction aux problemes de la peroxydation radicalaire des lipides, notamment au travers de la toxicite de l'oxygene. Effets des composes organonitres sur cette toxicite (etudes in vivo, in vitro, etudes de la mutagenicite)
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Bergknut, Magnus. "Characterization of PAH-contaminated soils focusing on availability, chemical composition and biological effects." Doctoral thesis, Umeå : Umeå University, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-789.

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Fisher, Edward. "Microbial transformation of arsenic and the characterization of Clostridium sp. strain OhILAs." 2006. http://etd1.library.duq.edu/theses/available/etd-12122006-184030/.

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Books on the topic "Reduction (Chemistry) Toxicity testing"

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Workshop on Toxicity Identification Evaluation: What Works, What Doesn't, and Developments for Effluents, Ambient Waters, and Other Aqueous Media (2001 Pensacola Beach, Fla.). Toxicity reduction and toxicity identification evaluations for effluents, ambient waters, and other aqueous media. Society of Environmental Toxicology and Chemistry, 2005.

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World Congress on Alternatives and Animal Use in the Life Sciences (3rd 1999 Bologna, Italy). Progress in the reduction, refinement, and replacement of animal experimentation: Proceedings of the 3rd World Congress on Alternatives and Animal Use in the Life Sciences, held in Bologna, Italy, from 29 August to 2 September 1999. Elsevier Science B.V., 2000.

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International Association of Biological Standardization., ed. IABS Symposium on Reduction of Animal Usage in the Development and Control of Biological Products: Proceedings of a symposium. S. Karger, 1986.

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Nakazawa, Hiroyuki, and Tsunehisa Makino. Naibunpitsu kakuran kagaku busshitsu ni kansuru seitai shiryō (saitaiketsu tō) bunsekihō no kaihatsu to sono jitsushiryō bunseki kekka ni motozuku hito kenkō eikyō ni tsuite no kenkyū (H11, seikatsu, 027). s.n., 2001.

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rg, Oehlmann Jo, and Markert, B. A. (Bernd A.), eds. Praktikum zur O kotoxikologie: Grundlagen und Anwendungen biologischer Testverfahren. Ecomed, 2003.

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Nihon Enu Yū Esu Kabushiki Kaisha. Kagaku busshitsu ni yoru kenkō eikyō ni kansuru jōhō shūshū gyōmu hōkokusho : Heisei 21-nendo. Nihon Enu Yū Esu Kabushiki Kaisha, 2010.

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Miyata, Naoki, Tetsuo Nagano, and Yoshihiro Abe. Kagaku busshitsu no kassei sanso dokusei no teiryōteki hyōka shuhō ni kansuru kenkyū (H12, seikatsu, 030): Heisei 12-nendo kōsei kagaku kenkyūhi hojokin seikatsu anzen sōgō kenkyū jigyō kenkyū hōkokusho. s.n., 2001.

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Endocrine Disrupters: Hazard Testing and Assessment Methods. Wiley, 2013.

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Quality, Virginia Department of Environmental. The reduction of toxics in state waters 2004: A report to the General Assembly of Virginia. Virginia Dept. of Environmental Quality, 2005.

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Virginia. Department of Environmental Quality. The reduction of toxics in state waters monitoring year 2005: A report to the General Assembly of Virginia. Virginia Department of Environmental Quality, 2006.

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Book chapters on the topic "Reduction (Chemistry) Toxicity testing"

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Braun, J. P., M. Bonnefoi, V. Burgat, and A. G. Rico. "Clinical Chemistry in Liver-Toxicity Testing: Differences between Species." In Clinical Chemistry. Springer US, 1989. http://dx.doi.org/10.1007/978-1-4613-0753-2_81.

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Idakwo, Gabriel, Joseph Luttrell IV, Minjun Chen, Huixiao Hong, Ping Gong, and Chaoyang Zhang. "A Review of Feature Reduction Methods for QSAR-Based Toxicity Prediction." In Challenges and Advances in Computational Chemistry and Physics. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-16443-0_7.

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Ankley, Gerald T., James R. Hockett, Donald I. Mount, and David R. Mount. "Early Evolution of the Toxicity Identification Evaluation Process: Contributions from the United States Environmental Protection Agency Effluent Testing Program." In The Handbook of Environmental Chemistry. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-18384-3_1.

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"Panel Discussion: Analytical Chemistry-Toxicity Testing Interface." In Advances in Chemistry, edited by I. H. (Mel) Suffet. American Chemical Society, 1986. http://dx.doi.org/10.1021/ba-1987-0214.ch037.

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"Attaining a Rational Refinement and Reduction in the Use of Live Animals: Studies on Cyanide Toxicity." In Advances In Animal Alternatives For Safety And Efficacy Testing. CRC Press, 1997. http://dx.doi.org/10.1201/9781439805817-57.

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Combes, R. D. "Progress in the Development, Validation and Regulatory Acceptance of In Vitro Methods for Toxicity Testing." In Reference Module in Chemistry, Molecular Sciences and Chemical Engineering. Elsevier, 2013. http://dx.doi.org/10.1016/b978-0-12-409547-2.02470-7.

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Bao, X. M. "Ferrous Ions and Manganous Ions." In Chemistry of Variable Charge Soils. Oxford University Press, 1997. http://dx.doi.org/10.1093/oso/9780195097450.003.0017.

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It has been seen in the previous chapter that, when organic reducing substances are in contact with soils, iron and manganese oxides of the soil can be reduced, producing ferrous and manganous ions. This reduction process is of particular significance for variable charge soils. This is because the contents of iron and manganese oxides in these soils are higher than those in constant charge soils, and therefore there is the basis for the production of large amounts of ferrous and manganous ions. On the other hand, the low pH of variable charge soils is one of the favorable factors in the reduction of iron and manganese. Hence, the possibility exists for the production of the reduced form of these two elements exists even under well-aerated conditions, provided that the soil contains organic matter. It is for these reasons that iron and manganese can actively participate in chemical reactions in variable charge soils in the form of ions, and they are of great significance in both soil genesis and plant nutrition. As a matter of fact, many reports have shown that the amount of manganous ions in strongly acid soils is so high that the toxicity of manganese may be one of the causes for the poor growth of plants. In this chapter, after the elucidation of the reduction and dissolution of iron and manganese, emphasis of discussions will be placed on the chemical equilibria of the two kinds of ions. Finally, the regimes of the two ions in variable charge soils under field conditions will be described. The solubility of iron oxides in soils is extremely low. The solubility product of Fe(OH)3 is about 10-38. Therefore, the concentration of Fe3+ ions in solution is only 10-8 M even at a pH of 4, if the concentration is determined solely by the solubility of the oxides. Similarly, the quantity of Mn4+ ions due to the dissolution of manganese oxides is also very small. On the other hand, because the solubility products of Fe(OH)2 and Mn(OH)2 are about 10-16 and 10-13, respectively, after reduction, ferrous and manganous (in this chapter the latter is simply referred to as manganese) ions can exist stably in soils.
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Banchetti-Robino, Marina Paola, and Jean-Pierre Noël Llored. "Reality Without Reification: Philosophy of Chemistry’s Contribution to Philosophy of Mind." In Essays in the Philosophy of Chemistry. Oxford University Press, 2016. http://dx.doi.org/10.1093/oso/9780190494599.003.0010.

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CHEMIST AND PHILOSOPHER of chemistry Joseph E. Earley has recently argued that, in order to resolve some of its most seemingly intractable problems, philosophy of mind should take into consideration the work currently being done in philosophy of chemistry. This is because there exist obvious parallels between questions that inform philosophy of chemistry and the so-called hard problem of consciousness in philosophy of mind. As David Chalmers describes it, the hard problem of consciousness is that of explaining the relationship between physical phenomena, such as brain states, and experience (i.e., phenomenal consciousness, mental states, or events with phenomenal qualities or “qualia”). The “hard problem” is related to the problem of the reduction of mental states to brain states and of the emergence of mental phenomena from physical phenomena. Similar issues are encountered in philosophy of chemistry, such as the reduction of higher-level chemical phenomena to lower-level physical states and the emergence of the higher-level phenomena from the lower-level states. An important and related concern that arises in both philosophical subfields, particularly when dealing with emergence, is the question of “downward causation,” that is, the question of whether the higher levels, such as chemical properties or mental states, exert downward causal influence over the lower levels, such as fundamental physical states or brain states. Given the parallels between these two fields, Earley argues that there are three different ways in which philosophy of chemistry can be of assistance to philosophy of mind. The first is by “developing an extended mereology applicable to chemical combinations.” The suggestion is that, if successful, such an extended mereology may also be applicable to the whole-parts relationships between complex systems such as the brain (and its associated mental phenomena) and individual brain states. A second way is by “testing whether ‘singularities’ prevent reduction of chemistry to microphysics.” If chemical “singularities” indeed prevent such reduction, one might extrapolate that mental “singularities” might also prevent the reduction of mental states to electrochemical interactions in the brain.
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koertge, Noretta. "Contingencies in Chemical Explanation." In Essays in the Philosophy of Chemistry. Oxford University Press, 2016. http://dx.doi.org/10.1093/oso/9780190494599.003.0013.

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“Chemistry has a position in the center of the sciences, bordering onto physics, which provides its theoretical foundation, on one side, and onto biology on the other, living organisms being the most complex of all chemical systems” (Malmström et al.). Thus begins a recent essay on the development of modern chemistry. Philosophers have long wrestled with how best to describe the exact relationship between chemistry and physics. Is it an example of a classic reduction? But before we ask whether chemistry could in principle be derived from physics, there is a prior question: How well integrated is the science of chemistry itself? This chapter argues that although there is a coherent explanatory core within chemical theory, contingency plays a larger role than is usually recognized. Furthermore, these phenomena at the boundaries of traditional chemistry education are where some of the most important current research is occurring. I will first adopt a quasi-historical approach in this essay, including anecdotes from my own educational trajectory. I then briefly discuss how our current understanding of the explanatory structure of chemistry should be reflected in education today. The professor of quantum chemistry at the University of Illinois in the 1950s told us a story from his PhD defense. His director, Linus Pauling, walked into the room and said something to this effect: “Well, Karplus, you’ve done a bunch of calculations on the hydrogen molecule ion (H2 +). Very nice. But you claim to be a chemist. So please write the Periodic Table on the board for us.” Who knows exactly what point Pauling was actually trying to make, but it reminds us of this basic point. The periodic table with its horizontal and vertical trends is still the basis of the classification of enormous amounts of information about the formulae and properties of chemical compounds. Mendeleev would not have understood talk of strontium-90, but he would have realized immediately that this product of nuclear testing would enter the body in a manner similar to calcium.
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Chugh, B. "Sustainable Corrosion Inhibitors for Concrete." In Sustainable Corrosion Inhibitors. Materials Research Forum LLC, 2021. http://dx.doi.org/10.21741/9781644901496-6.

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Green chemistry and sustainability encourages the significance of preserving the nature and individual’s wellbeing in cost effective way that intends to avoid toxicity and reduction of wastes. Therefore, the implication of green corrosion inhibitors in the field of concrete protection has also received immense attention these days. Indeed, the usage of such inhibitors is a well-known strategy for producing high performance concrete. In view of this, the present chapter discusses the research in the area of sustainable corrosion inhibitors for concrete assurance used commercially in various industries. It also highlights the concrete corrosion mechanisms and its protective measures, recent advances in this field.
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Conference papers on the topic "Reduction (Chemistry) Toxicity testing"

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Wilson, J. Jeffrey, Douglas W. Lee, Brett M. Yeske, and Fred Kuipers. "Testing of In Situ and Ex Situ Bioremediation Approaches for an Oil-Contaminated Peat Bog Following a Pipeline Break." In 2000 3rd International Pipeline Conference. American Society of Mechanical Engineers, 2000. http://dx.doi.org/10.1115/ipc2000-146.

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A biotreatability test was performed on oil-contaminated sphagnum peat moss from a 1985 pipeline spill of light Pembina Cardium crude oil at a bog near Violet Grove in central Alberta. Four tests were designed to simulate several field treatment approaches and to collect critical data on toxicity and leachability of this material. These tests included a bioslurry test, a soil microcosm test, an aerated water saturated peat column test, and a standard toxicity characteristic leachate potential (TCLP) test. In the saturated peat column tests, two nutrient amendment rates and a surfactant were te
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Gong, Bin, Yan-ping Huang, E. Jang, Jin-Hua Liu, Xiao-jiao Xia, and Yong-Fu Zhao. "Ongoing Research of Water Chemistry Effect on SCC Properties of Candidate Materials for SCWR." In 2013 21st International Conference on Nuclear Engineering. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/icone21-15876.

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One key issue during development of Super Critical Water Cooled Reactor (SCWR) is selection of water chemistry operating and control methods for core coolant. Under strong corrosive effect of supercritical water (SCW), the stress corrosion cracking (SCC) sensitivity of materials increases. Most of materials reliably used in PWR or BWR may not be competent for SCWR. Modified austenitic steel and nickel base alloy are hopeful due to low general corrosion rate but failures happen caused by SCC when meet incompatible chemistry environment. The possible options of water chemistry specifications for
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Lovell, John R., Omar Kulbrandstad, Sai Madem, and Daniel Meza. "Real-Time Digital Chemistry Offshore Transforms Flow Assurance Management." In Offshore Technology Conference. OTC, 2021. http://dx.doi.org/10.4043/31121-ms.

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Abstract Managing asphaltene accumulation in offshore Gulf-of-Mexico wells is a significant challenge. Until recently there was no real-time chemical monitoring that could advise on whether chemical inhibition was making a particular well more, or less, stable. This changed with the development of real-time hardware that directly measures the ratio of asphaltene flowing in the oil. A new generation of that hardware has now been launched which meets all of the Qualification and HSE requirements for deployment on offshore platforms. A microwave resonator was designed to receive fluid at wellhead
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Cuenca, Yolanda, Àngels Tejero, Supriyo Das, Daniel Brooke-Peig, Philip Martin, and Flavio Bechir. "Innovation to Reduce Operation Downtime in Sulfate Removal Offshore Applications." In Offshore Technology Conference. OTC, 2021. http://dx.doi.org/10.4043/31279-ms.

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Abstract Sulfate removal in injection water is standard practice to prevent scaling and souring in subsea oil reservoirs. Nanofiltration membranes have been used to this purpose since 1987, when FilmTec™ SR90-400 elements were installed in an offshore platform in the North Sea. The most pressing concern in this type of systems is membrane fouling, with the associated reduction in effective plant operation time and shorten element lifespan caused by the standard Clean-in-Place (CIP) protocols. The object of this research has been to test the latest developments in biofouling-resistant sulfate r
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Chen, Kok Hao, and Jong Hyun Choi. "Nanoparticle-Aptamer: An Effective Growth Inhibitor for Human Cancer Cells." In ASME 2009 International Mechanical Engineering Congress and Exposition. ASMEDC, 2009. http://dx.doi.org/10.1115/imece2009-11966.

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Semiconductor nanocrystals have unique optical properties due to quantum confinement effects, and a variety of promising approaches have been devised to interface the nanomaterials with biomolecules for bioimaging and therapeutic applications. Such bio-interface can be facilitated via a DNA template for nanoparticles as oligonucleotides can mediate the aqueous-phase nucleation and capping of semiconductor nanocrystals.[1,2] Here, we report a novel scheme of synthesizing fluorescent nanocrystal quantum dots (NQDs) using DNA aptamers and the use of this biotic/abiotic nanoparticle system for gro
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Laskowski, Christina, Todd Snelson, and Saadia Safir. "Sustain-A-Bear™: Applying Manufacturing Sustainability Practices to Plush Stuffed Animals." In ASME 2009 International Manufacturing Science and Engineering Conference. ASMEDC, 2009. http://dx.doi.org/10.1115/msec2009-84224.

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The stuffed toy market is quite large, with some manufacturers earning nearly half a billion dollars in revenue per year. However, the vast majority of manufacturers do not currently employ sustainable manufacturing techniques. This paper documents the development of a cost-effective stuffed product by placing an emphasis on sustainability within the design process while maintaining the user appeal of a traditional teddy bear. Specifications were determined by analyzing each of the four stages of the product timeline (extraction, manufacture, use, and disposal) to ensure that sustainability wa
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Wire, G. L., W. M. Evans, and W. J. Mills. "Fatigue Crack Propagation Tests on 304 Stainless Steel in High Temperature Water: Accelerated Cracking Rates and Transition to Lower Rates." In ASME/JSME 2004 Pressure Vessels and Piping Conference. ASMEDC, 2004. http://dx.doi.org/10.1115/pvp2004-2675.

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Previous fatigue crack propagation (FCP) tests on a single heat of 304 stainless steel (304 SS) specimens showed a strong acceleration of rates in high temperature water with 40–60 cc H2/kg H2O at 288°C, with rates up to 20X the air rates. The accelerated rates were observed under fully reversed conditions (R = −1) (Wire and Mills, 2001) and high stress ratios (R = 0.7 and 0.83) (Evans and Wire, 2001). In this study, a second heat of 304 SS has been tested at 243°C and 288°C and lower positive stress ratios (R = 0.3, 0.5). The second heat showed the large acceleration of rates at 288°C observe
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Anand, M., M. Hadfield, JL Viesca, and B. Thomas. "Experimental Study on the Effect of Marine Engine Lubricant Degradation on Tribological Performance of Cylinder Liner and Piston Rings Contact Using a Tuning Fork Technology Based Oil Sensor." In International Conference on Marine Engineering and Technology Oman. IMarEST, 2019. http://dx.doi.org/10.24868/icmet.oman.2019.009.

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An investigation was carried out to study the effect of changes in oil quality on its tribological performance using a tuning fork technology based oil sensor. In this research, a tribological testing system was commissioned, to simulate the piston ring-cylinder liner sliding contact, and to measure the lubricant condition in real-time using an oil sensor. Tribological contact between cylinder liners and piston rings in marine engines is the most affected region due to excessive thermo-mechanical stresses. At top dead centre, the effect of such stresses is at a maximum where piston-sliding spe
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Mayer, Luke J., and Darryl L. James. "Experimental Analysis of Flow Crossover in a Solar Thermochemical Reactor." In ASME 2012 10th International Conference on Fuel Cell Science, Engineering and Technology collocated with the ASME 2012 6th International Conference on Energy Sustainability. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/fuelcell2012-91398.

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As energy and fuel security continue to be of increasing importance to economies around the world, countries are looking to move away from oil dependency. Energy solutions are being sought in the area of solar fuels to meet these growing needs. Concentrated solar thermochemical technology has the potential to directly convert sunlight into a useable, carbon-neutral liquid fuel that can be easily stored and integrated into our existing forms of energy demand such as transportation and heating fuels. Ongoing research performed by several groups at Sandia National Laboratories seeks to fundamenta
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Barnes, Charles M., W. C. Richardson, DeWayne Husser, and Matthias Ebner. "Fabrication Process and Product Quality Improvements in Advanced Gas Reactor UCO Kernels." In Fourth International Topical Meeting on High Temperature Reactor Technology. ASMEDC, 2008. http://dx.doi.org/10.1115/htr2008-58039.

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A major element of the Next Generation Nuclear Plant (NGNP)/Advanced Gas Reactor (AGR) Fuel Development and Qualification Program is developing fuel fabrication processes to produce high quality uranium-containing fuel kernels, TRISO-coated particles and fuel compacts needed for planned irradiation tests. The goals of the program also include developing the fabrication technology to mass produce this fuel at low cost. Kernels for the first AGR test, AGR-1, consisted of uranium oxycarbide (UCO) microspheres that were produced by an internal gelation process followed by high temperature steps to
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