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Dissertations / Theses on the topic 'Regeneration development'

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1

Morgan, James. "Gambling with regeneration : seaside resort regeneration and casino development." Thesis, University of Westminster, 2013. https://westminsterresearch.westminster.ac.uk/item/8z0z2/gambling-with-regeneration-seaside-resort-regeneration-and-casino-development.

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The United Kingdom’s seaside resorts are in decline. This has been addressed by various regeneration strategies. The Gambling Act 2005 threw a potential lifeline to some seaside resorts that wished to utilise casinos as cultural regeneration tools. However, this is a unique example of a regeneration lever that generates new policy processes. This thesis explores the development and passage of the casino regeneration strategy in three seaside resorts: Great Yarmouth, Scarborough and Torbay. All of these resorts had differing cultural and socio-economic contexts. Linking the perceptions of this
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Psychoyos, Delphine. "Regeneration of the organizer." Thesis, University of Oxford, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.299176.

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Moss, Nicole. "Regeneration in the Pilidium." Thesis, University of Oregon, 2018. http://hdl.handle.net/1794/23138.

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Ability to regenerate is found in many groups of metazoans but the majority of research is focused on adults from just a few taxa, such as planarians and hydra (Agata and Inoue, 2012; Bely et al., 2014). Increasing the diversity of study organisms and life stages can reveal new and interesting aspects of regeneration mechanisms. This study focuses on regeneration of the nemertean pilidium larva. The planktotrophic pilidium of Maculaura alaskensis provides a unique model in which to observe several components of the regeneration process. Here I have documented a timeline for regeneration and ha
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Saleem, Rimah Abdullah A. "Salisphere development for salivary gland regeneration." Thesis, King's College London (University of London), 2018. https://kclpure.kcl.ac.uk/portal/en/theses/salisphere-development-for-salivary-gland-regeneration(c74db61c-6d62-47a4-946e-56485316767a).html.

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Salivary gland stem/progenitor cells are considered a promising solution for ameliorating salivary gland damage. mTOR signalling is known to play a role during salivary gland atrophy as ligation of the salivary main excretory duct results in the activation of mammalian target of rapamycin (mTOR). Cultured mouse and human salivary gland stem/progenitor cells in vitro are able to form spherical non-adherent clusters named salispheres. As mTOR plays a role during glandular atrophy, salispheres were cultured from un-operated, ligated and de-ligated glands. This project aimed to understand several
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Furze, Alistair P. "Novel biomaterial development for cartilage regeneration." Thesis, University of Manchester, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.695272.

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6

Cahill, Thomas Joseph. "Macrophages in cardiac development, repair and regeneration." Thesis, University of Oxford, 2018. http://ora.ox.ac.uk/objects/uuid:13637b9e-6b8b-4978-8bb6-533bbe6fa1ce.

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Background & Aims: Macrophages are highly plastic cells of the innate immune system with a functional repertoire spanning homeostasis, inflammation, repair and remodelling. Originally described as immune cells responsible for phagocytosis and cytokine production, in recent years a plethora of non-classical, tissue-specific, and subspecialised roles for macrophages have emerged. Macrophages have been implicated in organogenesis during embryonic development, and tissue regeneration after injury, often viewed as a recapitulation of development. Understanding the mechanisms underlying these 'troph
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7

Werner, Steffen. "Growth and Scaling during Development and Regeneration." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2016. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-208033.

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Life presents fascinating examples of self-organization and emergent phenomena. In multi-cellular organisms, a multitude of cells interact to form and maintain highly complex body plans. This requires reliable communication between cells on various length scales. First, there has to be the right number of cells to preserve the integrity of the body and its size. Second, there have to be the right types of cells at the right positions to result in a functional body layout. In this thesis, we investigate theoretical feedback mechanisms for both self-organized body plan patterning and size contro
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McDonald, Cameron. "Investigations in Cardiac Development and Cardiac Regeneration." Thesis, Griffith University, 2009. http://hdl.handle.net/10072/366063.

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Cardiovascular disease and congenital heart disease impose a massive burden on society around the world. From the cost in terms of lost human lives and diminished quality of life, to the financial expense of ongoing medical treatment, the heart’s inability to effectively repair and regenerate itself presents a major challenge for medical research. The research conducted within this thesis hoped to contribute to our knowledge of the molecular pathways of myocardial development, and to explore the potential of olfactory derived stem cells to repopulate insulted myocardium. A combination of molec
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Lee, Cheuk-hei, and 李卓禧. "Culture-led regeneration: an opportunity for sustainable urban regeneration in Hong Kong?" Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B49885315.

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Culture-led regeneration policy has become a global trend in many major cities worldwide (UNCHS, 2004; Miles and Paddison, 2005). While overseas governments such as the United Kingdom, Japan and Australia have directed their regeneration policies to encourage the creative class and industries; Hong Kong is again left behind. Some scholars suggest that the culture-led strategy can act as the twenty-first century driver for regeneration, able to better preserve social networks and capital, and hence bring greater benefit to the local residents (Szeto, 2007). However, the methods of promoting cu
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10

Farnden, Craig. "Development of regeneration standards for sustainable forest management." Thesis, University of British Columbia, 2010. http://hdl.handle.net/2429/23633.

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Linking regeneration activities to desired future forest conditions is a critical component of sustainable forest management. In much of North America, regeneration standards are an important administrative tool for ensuring this goal, but the links to predicted future outcomes are often weak. There is a need for developing regeneration standards that are solidly based on defensible predictions of future stand attributes and are indicators of a wide range of forest values. This dissertation describes the application of an analysis framework wherein many variations of simulated juvenile stand s
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11

Hawthorne, Alicia Lynn. "The Development and Regeneration of the Serotonergic System." Case Western Reserve University School of Graduate Studies / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=case1264027000.

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12

Hassan, Enas. "Development of amine functional hydrogels for corneal regeneration." Thesis, University of Sheffield, 2014. http://etheses.whiterose.ac.uk/8468/.

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The aim of this thesis was to develop a synthetic polymethacrylate based hydrogel capable of regenerating a corneal epithelium for the purposes of treating blindness caused by limbal stem cell deficiency. Deficiency of limbal epithelial cells (LECs) causes conjunctival epithelial cells to move over the cornea, resulting in painful scaring, vascularisation and corneal opacity. Unilateral defects can be treated using LEC cultured from the unaffected eye, transplanting them to the affected cornea after scar tissue is removed. The underlying wound bed is often damaged, however, hence the need to d
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Sobkow, Lidia. "Development of transgenic Ambystoma mexicanum (axolotl) to study cell fate during development and regeneration." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2006. http://nbn-resolving.de/urn:nbn:de:swb:14-1147931726524-14021.

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The establishment of transgenesisi in axolotls is crucial for studying development and regeneration, as it would allow for long-term fate tracing as well as gene expression analysis, therefore we were interested in both obtaining animals expresing the transgene with little mosaicism in F0 generation and transgenesis. We demonstrate here that plasmid injection into one cell stage axolotl embryo generates transgenic animals that display germline transmission of a transgene. However, the efficiency of simple plasmid injection is very low, expression of the transgene is mosaic and seems to be prom
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Toma, Jeremy Steven. "Immunohistochemical analyses of nervous system structure, development and regeneration." Thesis, University of British Columbia, 2006. http://hdl.handle.net/2429/31284.

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Specific aspects of nervous system structure, development, and regeneration were investigated in two separate studies. The first study was concerned with development of sensory root entry zones. Sensory information enters the central nervous system (CNS) via root entry zones where sensory axons span a glial environment consisting of Schwann cells in the peripheral nervous system (PNS) and astrocytes and oligodendrocytes in the CNS. Little is known about the postnatal development of the glial elements of many root entry zones. I sought to establish a comparative developmental timecourse o
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Lopez-Jimenez, Cristobal. "Control of Joint Spacing During Fin Development and Regeneration." Thesis, Université d'Ottawa / University of Ottawa, 2015. http://hdl.handle.net/10393/32574.

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The zebrafish (Danio rerio) has emerged as a model to study vertebrate development due to rapid ontogenetic processes with external embryonic development. It is also an excellent model to study the mechanisms of regeneration and in this respect, the caudal fin is particularly convenient because it is easily accessible for experimental manipulation. Collection of quantitative data and postulation of theoretical models have become an attractive practice to explain complex biological problems. These models are used to test hypothetical mechanisms and predict results, but they also require calibra
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Morgado, Patrícia Isabel da Cruz. "Development of different drug delivery systems for skin regeneration." Master's thesis, Universidade da Beira Interior, 2011. http://hdl.handle.net/10400.6/982.

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The human body has different fluids that are hostile environments for biologically active molecules. To overcome this arbitrary, several drug delivery systems have been developed. These systems not only protect all unstable biological active compounds from enzymatic degradation in the human body but also allow a sustained and targeted release of drugs. They contribute for decreasing drug dose required to achieve the desired therapeutic effect. Hydrogels, with their important characteristics, have been widely used in the development of these systems however, the quantity of drug loaded into the
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Ren, Jiongyu. "Development of melt electrospun composite scaffolds for bone regeneration." Thesis, Queensland University of Technology, 2017. https://eprints.qut.edu.au/108824/1/Jiongyu%20Edward_Ren_Thesis.pdf.

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This thesis was a step forward in the development of an effective and patient-specific treatment for bone tissue loss using synthetic tissue engineered constructs. A novel polycaprolactone/strontium-substituted bioactive glass composite was fabricated into scaffolds with highly ordered fibre structure and promising osteogenic potential using an advanced additive manufacturing technique known as melt-electrospinning. The findings of this thesis provide an indispensable link in our understanding of future cell-free treatment for bone defects utilising fully synthetic bioactive scaffolds. The the
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Cartes, Ivan. "Sustainable principles of neighbourhood regeneration with reference to Chile." Thesis, University of Nottingham, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.339649.

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Chung, Yuk-ming Christopher. "An investigation of property-LED urban regeneration in Hong Kong." Click to view the E-thesis via HKUTO, 1999. http://sunzi.lib.hku.hk/hkuto/record/B42575060.

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Wyatt, Cameron. "Optic axon guidance during development and regeneration in the zebrafish." Thesis, University of Edinburgh, 2011. http://hdl.handle.net/1842/5947.

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Directed regeneration of axons in the CNS has potential for the treatment of CNS disorders and injuries. In contrast to mammals, following optic nerve lesion zebrafish regenerate axons that navigate to their correct targets and form new synapses leading to functional recovery. Correct pathfinding is thought to rely on a range of molecular cues in the CNS which the growing axon expresses receptors for. However, the specific guidance cues are not well elucidated. It is likely that a proportion of them will be the same as during development, while some may be specific to regeneration. Alternative
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Franks, Tom R. "Managing regeneration projects: what can we learn from international development." University of Bradford, 2007. http://hdl.handle.net/10454/2836.

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Yes<br>This seminar paper analyses the links between regeneration and international development, and describes project approaches in international development. In the light of these two perspectives it then goes on to discuss the main issue facing management of development or regeneration projects to-day.
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Carroll, Kelli Jane. "The Role of Estrogen Signaling in the Induction, Specification, and Proliferation of Hematopoietic Stem Cells." Thesis, Harvard University, 2014. http://dissertations.umi.com/gsas.harvard:11446.

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Hematopoietic Stem Cells (HSCs) are characterized by their ability to both self-renew and give rise to all lineages of the blood system. A recent chemical genetic screen identified 17&beta;-estradiol (estrogen) as a novel modifier of the expression of the conserved HSC markers runx1 and cmyb in the Aorta-Gonad-Mesonephros of developing zebrafish. Exposure to exogenous estrogen during the development of the hematopoietic niche impeded specification of hemogenic endothelium and the subsequent emergence of HSCs via antagonism of somitic-derived VEGF signaling. Conversely, inhibition of endogenous
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Ramay, Hassna Rehman. "Development of porous scaffolds for bone tissue engineering /." Thesis, Connect to this title online; UW restricted, 2004. http://hdl.handle.net/1773/10588.

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Ahmad, Abadi Mohammad. "Development and application of novel genetic transformation technologies in maize (Zea mays L.)." Phd thesis, Universität Potsdam, 2007. http://opus.kobv.de/ubp/volltexte/2007/1457/.

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Plant genetic engineering approaches are of pivotal importance to both basic and applied research. However, rapid commercialization of genetically engineered crops, especially maize, raises several ecological and environmental concerns largely related to transgene flow via pollination. In most crops, the plastid genome is inherited uniparentally in a maternal manner. Consequently, a trait introduced into the plastid genome would not be transferred to the sexually compatible relatives of the crops via pollination. Thus, beside its several other advantages, plastid transformation provides transg
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Wilson, Stephen G. "ROLE OF HAIRY-RELATED (HER) GENES DURING VERTEBRATE RETINAL DEVELOPMENT AND REGENERATION." UKnowledge, 2016. http://uknowledge.uky.edu/biology_etds/36.

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Development and regeneration of the vertebrate eye are the result of complex interactions of regulatory networks and spatiotemporally controlled gene expression events. During embryonic retinal development, the coordination of cell signaling and transcriptional regulation allows for a relatively homogenous sheet of neuroepithelial cells to proliferate and differentiate in-to a multilayered, light sensitive retinal tissue. Following injury, the retinas of many cold-blooded vertebrates, such as the zebrafish, undergo a proliferative response that results not only in new retinal cells of the corr
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Mingorance, Jiménez de la Espada Ana. "MAG, Nogo-A and NgR in Hippocampal Development and Regeneration." Doctoral thesis, Universitat de Barcelona, 2006. http://hdl.handle.net/10803/841.

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The adult central nervous system (CNS) has a very little capability to regrow its connections after lesion. The lack of axonal regeneration is a multifactorial problem, which is mainly due to the presence of inhibitory molecules in the CNS. Two main families of inhibitors exist, that of the so-called myelin-associated inhibitors, and that of the chondoritin-sulfate proteoglycans (CSPG). The question this thesis aims to address is the <i>role of myelin-associated inhibitors in the regeneration of cortical connections</i>. To do so, the model we have used is the entorhino-hippocampal connection
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Sousa, Filipe Pinto Teixeira. "Development and functional regeneration of the zebrafish lateral line system." Doctoral thesis, Universitat Pompeu Fabra, 2012. http://hdl.handle.net/10803/78873.

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Per a aquesta tesi, utilitzo la línia lateral del peix zebra com a sistema model per adreçar dues qüestions fonamentals: En una primera línia d’investigació exploro la relació entre la funció d’un òrgan i la seva arquitectura. La regeneració de cèl.lules ciliades a la línia lateral del peix zebra ocorre mitjançant la divisió dels seus progenitors en determinades posicions dins les zones ventral i dorsal del neuromast. Durant la regeneració de les cèl.lules ciliades, es forma una línia de simetria vertical, que bisecciona l’epiteli del neuromast en dues meitats de polaritats planars opo
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Ott, Cassandra Holzgartner. "Development of bi-layer mineralized bone and cartilage regeneration template." Thesis, Massachusetts Institute of Technology, 2005. http://hdl.handle.net/1721.1/33620.

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Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 2005.<br>Includes bibliographical references (leaves 86-88).<br>Porous collagen-glycosaminoglycan (CG) scaffolds have been studied extensively and proven to be capable of tissue regeneration in vivo for applications including skin regeneration templates, hollow nerve guides and conjunctiva regeneration. While the current CG scaffold has been thoroughly examined both mechanically and clinically, it has yet to prove appropriate for load- bearing applications. This study will investigate the mecha
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Liu, J. "Development and regeneration of the pineal region of the diencephalon." Thesis, University College London (University of London), 2014. http://discovery.ucl.ac.uk/1421354/.

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Organizer is a group of cells that induces and patterns surrounding tissues during embryo development. Previous studies of organizers were mainly based on transplantation of various pieces of tissues. This project first aimed to find out putative organizers using a novel method, which was to characterize organizers based on patterns of syn-expression genes. The differential microarray assays selected a list of gene that are enriched or depleted in three known organizers (Hensen’s node, notochord and floor plate and zone of polarizing activity). Whole-mount in-situ hybridisation, histological s
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Anderson, Gail. "Housing-led regeneration in east Durham : uneven development, governance, politics." Thesis, Durham University, 2015. http://etheses.dur.ac.uk/11105/.

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This research investigates housing-led regeneration in the post-industrial area of East Durham to examine whether a gap exists between policy expectation and regeneration, on-the-ground. By engaging with the themes of uneven development and stigma and marginality, the thesis argues that housing-led regeneration policies have exacerbated already existing unevenness and marginality, in their bid to regenerate areas and promote sustainability. This process is played out in the face of shifting economic and political issues. The housing and wider economic market boom of the early to mid 2000’s wit
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Meda, Francesca. "The role of ROS signaling in adult regeneration and development." Thesis, Paris Sciences et Lettres (ComUE), 2016. http://www.theses.fr/2016PSLEE007/document.

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Ces dernières années, il est apparu que les espèces réactives de l'oxygène (ROS) ne sont pas seulement des substances délétères qui induisent des dommages de molécules biologiques, mais qu’elles sont également impliquées dans la signalisation cellulaire. Des niveaux contrôlés de H2O2 sont en particulier impliqués dans le processus de régénération chez différentes espèces. Nous avons donc étudié la régulation de la signalisation de H2O2 au cours de régénération de la nageoire caudale chez le poisson zèbre adulte. Nous avons montré que les nerfs contrôlent les niveaux de H2O2 à la fois dans les
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Meda, Francesca. "The role of ROS signaling in adult regeneration and development." Electronic Thesis or Diss., Paris Sciences et Lettres (ComUE), 2016. http://www.theses.fr/2016PSLEE007.

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Ces dernières années, il est apparu que les espèces réactives de l'oxygène (ROS) ne sont pas seulement des substances délétères qui induisent des dommages de molécules biologiques, mais qu’elles sont également impliquées dans la signalisation cellulaire. Des niveaux contrôlés de H2O2 sont en particulier impliqués dans le processus de régénération chez différentes espèces. Nous avons donc étudié la régulation de la signalisation de H2O2 au cours de régénération de la nageoire caudale chez le poisson zèbre adulte. Nous avons montré que les nerfs contrôlent les niveaux de H2O2 à la fois dans les
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Lang, Anthony. "Regulation and regeneration : how do development plans affect urban regeneration? a case study analysis of two Urban Development Corporations and the emerging Unitary Development Plans of their component local authorities." Thesis, University of Newcastle Upon Tyne, 1999. http://hdl.handle.net/10443/447.

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Urban Development Corporations (UDCs) are perhaps the most outstanding examples of government action in the field of urban regeneration in the last twenty years. In order to promote regeneration UDCs were given development control powers over Urban Development Areas (UDAs). These powers were taken from local government and this caused well-documented resentment in many cases. However, local government retained all development plan-making powers. Following two town planning acts (in 1990 and 1991) central government gave the development plan more power in the development control process (throug
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Healey, Sean P. "The development of an abandoned-field forest in southwestern Costa Rica /." Thesis, Connect to this title online; UW restricted, 2001. http://hdl.handle.net/1773/5562.

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Kennedy-Skipton, Henry G. "Property development and urban regeneration : policy-led office development in Glasgow/Clydebank and Manchester/Salford." Thesis, University of Glasgow, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.363295.

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Qiu, Qingchao. "TGF-β, WNT, AND FGF SIGNALING PATHWAYS DURING AXOLOTL TAIL REGENERATION AND FORELIMB BUD DEVELOPMENT". UKnowledge, 2019. https://uknowledge.uky.edu/neurobio_etds/24.

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Tgf-β, Wnt, and Fgf signaling pathways are required for many developmental processes. Here, I investigated the requirement of these signaling pathways during tail regeneration and limb development in the Mexican axolotl (Ambystoma mexicanum). Using small chemical inhibitors during tail regeneration, I found that the Tgf-β signaling pathway was required from 0-24 and 48-72 hours post tail amputation (hpa), the Wnt signaling pathway was required from 0-120 hpa, and the Fgf signaling pathway was required from 0-12hpa. Tgf-β1 was upregulated after amputation and thus may mediate Tgf-β signaling pa
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Vázquez-Figueroa, Eduardo. "Development of a novel dehydrogenase and a stable cofactor regeneration system." Atlanta, Ga. : Georgia Institute of Technology, 2008. http://hdl.handle.net/1853/31685.

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Thesis (Ph.D)--Chemical Engineering, Georgia Institute of Technology, 2009.<br>Committee Chair: Bommarius, Andreas S.; Committee Member: Doyle, Donald F.; Committee Member: Koros, William J.; Committee Member: Moore, Jeffre C.; Committee Member: Prausnitz, Mark R. Part of the SMARTech Electronic Thesis and Dissertation Collection.
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Birgersson, Henrik. "Development of a regeneration procedure for commercial automotive three-wy catalysts." Licentiate thesis, KTH, Chemical Engineering and Technology, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-367.

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<p>Car exhaust catalysts were introduced in the early 1980’s, to limit the release of pollutants such as hydrocarbons, carbon monoxides and nitrogen oxides. These catalysts contain noble metals such as palladium (Pd), platinum (Pt) and rhodium (Rh) and are able to simultaneously abate all three of the above-mentioned pollutants, hence the name three-way catalyst (TWC). The exposure to high temperatures (800-1000 °C) during operation and the presence of additives in petrol such as lead, calcium, silicon, magnesium, manganese, chromium, sulphur and phosphorus will after a certain time start to l
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Vázquez-Figueroa, Eduardo. "Development of a novel dehydrogenase and a stable cofactor regeneration system." Diss., Georgia Institute of Technology, 2008. http://hdl.handle.net/1853/31685.

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The first goal of this work focused on the development of an amine dehydrogenase (AmDH) from a leucine dehydrogenase using site-directed mutagenesis. We aimed at reductively aminating a prochiral ketone to a chiral amine by using leucine dehydrogenase (LeuDH) as a starting template. This initial work was divided into two stages. The first focused mutagenesis to a specific residue (K68) that we know is key to developing the target functionality. Subsequently, mutagenesis focused on residues known to be in close proximity to a key region of the substrate (M65 and K68). This approach allowed
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Köhle, Bernhard. "Evaluating sub-regional economic development regeneration partnerships : a new institutionalist critique." Thesis, University of Warwick, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.418171.

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Birgersson, Henrik. "Development of a regeneration procedure for commercial automotive three-way catalysts /." Stockholm, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-367.

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Jenkins, Robert. "The expression of immediate early genes in neuronal development and regeneration." Thesis, University of Cambridge, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.260577.

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Georgiadis, Vassilios. "The role of galectin-1 in skeletal muscle development and regeneration." Thesis, University of Sussex, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.488604.

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Galectin-1 is a p-galactoside binding lectin that has been implicated in a variety of cellular processes in different tissues, including skeletal muscle. Initial studies investigating the phenotype of a null mouse model for galectin-1 suggested that there were no obvious differences between the musculature of the null mouse and that of the wild-type mouse. However, in vitro studies suggested that the addition of galectin-1 Improved the fusion of myoblasts to myotubes and caused dermal fibroblasts to convert to the myogenic lineage.
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Proctor, John William. "Investigation and development of the diesel particulate filter autoselective regeneration system." Thesis, Loughborough University, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.547385.

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Holmes, Roisin Anne. "Development of biomimetic hydrogels as cell-laden devices for muscle regeneration." Thesis, University of Leeds, 2017. http://etheses.whiterose.ac.uk/19346/.

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The aim of this thesis was to develop a novel cross-linking strategy to prepare defined collagen-based hydrogel networks to investigate stiffness-induced cell differentiation for skeletal muscle tissue engineering. Volumetric muscle loss (VML) occurs with traumatic injury or aggressive tumour ablation and results in a diminished natural capacity for repair. Whilst autologous muscle transfer offers the gold standard treatment option, the level of success is limited by surgical expertise, availability of healthy tissue, donor site morbidity and a loss of muscle strength and function due to scar
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McCormick, Aleesha Marie. "Development and Implementation of Multi-Cued Guidance Strategies for Axonal Regeneration." University of Akron / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=akron1417449988.

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Wilcock, Caroline. "The development of nanostructured calcium phosphate biomaterials for bone tissue regeneration." Thesis, University of Sheffield, 2015. http://etheses.whiterose.ac.uk/11400/.

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Bizzarri, Elena. "Study of development and regeneration of corneal innervation in transgenic mice." Electronic Thesis or Diss., Sorbonne université, 2024. https://accesdistant.sorbonne-universite.fr/login?url=https://theses-intra.sorbonne-universite.fr/2024SORUS175.pdf.

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La cornée, structure transparente et avasculaire située dans le segment antérieur de l'œil, est le tissu le plus innervé du corps humain. Elle reçoit principalement des entrées sensorielles de la branche ophtalmique du nerf trijumeau. Les axones cornéens se répartissent de la couche la plus profonde (stroma) à la couche la plus superficielle (épithélium) et présentent une organisation distincte en forme de spirale. De plus, les nerfs cornéens sont essentiels au maintien de l'homéostasie tissulaire en interagissant avec les cellules épithéliales qui libèrent des neuropeptides. Bien que les tech
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49

Rost, Fabian. "Data-driven Modeling of Cell Behavior, Morphogenesis and Growth in Regeneration and Development." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2017. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-227467.

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The cell is the central functional unit of life. Cell behaviors, such as cell division, movements, differentiation, cell death as well as cell shape and size changes, determine how tissues change shape and grow during regeneration and development. However, a generally applicable framework to measure and describe the behavior of the multitude of cells in a developing tissue is still lacking. Furthermore, the specific contribution of individual cell behaviors, and how exactly these cell behaviors collectively lead to the morphogenesis and growth of tissues are not clear for many developmental an
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Chung, Yuk-ming Christopher, and 鍾育明. "An investigation of property-LED urban regeneration in Hong Kong." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1999. http://hub.hku.hk/bib/B42575060.

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