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Journal articles on the topic 'Régulations endocrine et paracrine'

Author: Grafiati
Published: 7 December 2024
Last updated: 31 July 2025

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1

Gallo-Payet, N. "Nouveaux concepts sur la régulation de la sécrétion d'aldostérone ; interactions endocrines, paracrines, autocrines et neurocrines." médecine/sciences 9, no. 8-9 (1993): 943. http://dx.doi.org/10.4267/10608/3015.

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2

Kjekshus, Harald, Otto A. Smiseth, Randi Klinge, Erik Øie, Marit E. Hystad, and Håvard Attramadal. "Regulation of ET: pulmonary release of ET contributes to increased plasma ET levels and vasoconstriction in CHF." American Journal of Physiology-Heart and Circulatory Physiology 278, no. 4 (2000): H1299—H1310. http://dx.doi.org/10.1152/ajpheart.2000.278.4.h1299.

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Endothelin (ET) contributes to the increased systemic vascular resistance and elevated cardiac filling pressures seen in congestive heart failure (CHF). We investigated to what extent ET-mediated vasoconstriction in CHF occurs through an endocrine action of elevated plasma ET or by an autocrine/paracrine mechanism related to induction of vascular ET gene expression. Three weeks of pacing (225 beats/min) induced a marked release of ET-1 from the pulmonary circulation with a sixfold elevation of arterial plasma ET in CHF pigs compared with sham-operated pigs. Arterial plasma ET was the strongest
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3

Towler, Dwight A. "Bone morphogenetic proteins." Blood 114, no. 10 (2009): 2012–13. http://dx.doi.org/10.1182/blood-2009-06-228544.

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Abstract BMP2 and BMP4 play crucial inductive roles during development. In this issue of Blood, Shao et al demonstrate that an intricate network of paracrine BMP2/4 signals also regulates angiogenesis—and will very likely interact with endocrine BMP cues during wound repair.1
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4

Tonon, MC, C. Patte, J. Leprince, et al. "Les endozépines : peptides ubiquistes à activités intracrine, autocrine, paracrine, endocrine et exocrine." médecine/sciences 13, no. 5 (1997): 702. http://dx.doi.org/10.4267/10608/441.

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5

Sallon, C., I. Boulay, D. Logeart-Avramoglou, et al. "Nouvelles perspectives dans l’action paracrine et/ou endocrine des BMPs au niveau hypophysaire." Annales d'Endocrinologie 74, no. 4 (2013): 434. http://dx.doi.org/10.1016/j.ando.2013.07.698.

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6

Brandt, R. R., D. M. Heublein, M. T. Mattingly, M. R. Pittelkow, and J. C. Burnett. "Presence and secretion of atrial natriuretic peptide from cultured human aortic endothelial cells." American Journal of Physiology-Heart and Circulatory Physiology 268, no. 2 (1995): H921—H925. http://dx.doi.org/10.1152/ajpheart.1995.268.2.h921.

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The endothelium is the production site of several potent vasoactive substances that modulate vascular tone and growth. The present study was undertaken to investigate the presence and secretion of atrial natriuretic peptide (ANP) immunoreactivity from vascular endothelial cells. ANP immunoreactivity was present in cultured human aortic endothelial cells by both immunohistochemical staining and radioimmunoassay. ANP immunoreactivity was also detectable in culture medium from human aortic endothelial cells in low picogram concentrations. These findings suggest that vascular endothelium is a site
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7

Manshaei, Saba, Thea Willis, Dominic Withers, Jesus Gil, Cynthia Lilian Andoniadou, and Juan Pedro Martinez-Barbera. "Paracrine Signalling From SOX2-Expressing Pituitary Embryonic Cells Is Required for Terminal Differentiation of Hormone-Producing Cells." Journal of the Endocrine Society 5, Supplement_1 (2021): A547—A548. http://dx.doi.org/10.1210/jendso/bvab048.1115.

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Abstract The pituitary gland is the master regulator of the endocrine system, housing six major hormone producing cell types. This gland is derived from Rathke’s Pouch, an invagination of the oral ectoderm. Hormone-producing pituitary cell lineages are derived from a population of embryonic cells expressing SOX2. ZFP36L1/Butyrate Response Factor 1 (BRF1) is an RNA binding protein that binds and targets mRNAs of various cytokines and chemokines for degradation prior to translation, attenuating secretion of inflammatory factors (Herranz et al. 2015). Here, we show that BRF1 is a novel marker exp
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8

Ojog, Victor. "Morphofunctional traits and reactivity of the portal vein." Moldovan Medical Journal 66, no. 2 (2023): 83–90. http://dx.doi.org/10.52418/moldovan-med-j.66-2.23.13.

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Background: Portal vein is the most enigmatic vessel of our body because it regulates own contractile performances using a special pace-maker mechanism represented by cells of Cajal. The contribution of various metabolic mediators and natural vasotropic agents in the control of the portal blood circuit is much less studied compared to the arterial system in general and the hepatic system in particular. The studies designed on the structure, function, and reactivity of the portal vein in different preconditioning have brought some common but also distinct evidence of the arterial system. Nitric
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9

Smekalova, Araksiya, Elena K. Montvila, Olga Konovalova, Olga Mityashova, and Irina Lebedeva. "PSII-32 In vitro effect of growth hormone on progesterone production by large preovulatory follicles depends on the hen age and follicular layers interaction." Journal of Animal Science 98, Supplement_4 (2020): 372. http://dx.doi.org/10.1093/jas/skaa278.654.

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Abstract Growth hormone (GH) is an endocrine and paracrine/autocrine regulator of the hen ovarian function, with the GH receptor concentration in the granulosa layer (GL) being maximum in the largest preovulatory follicle (Lebedeva et al. 2004, Biol.Reprod. 71:1174–1181). In the present study, GH effects on in vitro production of progesterone by GL from the two largest yellow follicles (F1 and F2) were investigated due to the hen age and the presence of the theca layer (TL). Young hens with long clutch (YLC, 32–33 week-old, >10 eggs per clutch) and old hens with short clutch (OSC, 74–76
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10

Bashirov, Farid V., Ilnur I. Salafutdinov, Michail E. Sokolov, et al. "Umbilical Cord Blood Mononuclear Cells for Ex-Vivo Gene Therapy." Blood 132, Supplement 1 (2018): 5797. http://dx.doi.org/10.1182/blood-2018-99-113462.

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Abstract Cell-mediated (ex-vivo) gene therapy for the treatment of adenosine deaminase (ADA)-deficient severe combined immunodeficiency (SCID) had started in 1990 and nowadays it is the first marketing approval of an ex vivo gene therapy in Europe. The method based on ex-vivo transduction of peripheral blood lymphocytes with retroviral vector carrying the functional ADA gene in 2002 have been improved to use hematopoietic stem cell (HSC) for ex-vivo transduction with 100% survival and the evidence of safety and efficacy. Remarkably, umbilical cord blood mononuclear cells (UCB-MC) were successf
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11

Songsasen, N., C. Guzy, and D. E. Wildt. "121 ALGINATE-FIBRIN GEL MATRIX PROMOTES IN VITRO GROWTH OF DOG SECONDARY FOLLICLES." Reproduction, Fertility and Development 24, no. 1 (2012): 173. http://dx.doi.org/10.1071/rdv24n1ab121.

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A previous study from our laboratory has demonstrated that preantral follicles from the dog that are cultured in alginate are able to grow and produce steroid hormones (Songsasen et al. 2011 Reproduction 142, 113–122). Here we investigated the influence of using a combination of alginate and a degradable biomaterial, fibrin, on dog follicle development in vitro. We hypothesised that the alginate and fibrin gel matrix would be superior to alginate alone because the former has dynamic mechanical properties that permit more expansive follicle development than the inert alginate-only system. Secon
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12

Reagan, Michaela, Carolyne Falank, Heather Fairfield, Michelle McDonald, Peter Croucher, and Clifford J. Rosen. "Multiple Myeloma Progression: Dependence on Bone Marrow Adipose Tissue." Blood 128, no. 22 (2016): 3262. http://dx.doi.org/10.1182/blood.v128.22.3262.3262.

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Abstract Multiple myeloma (MM) is characterized by clonal proliferation of transformed plasma cells1 and is extremely dependent on bone marrow (BM) niche molecules and cells, such as osteoclasts. Unlike osteoclasts, the roles of BM adipocytes (BMAs) in MM are poorly understood, despite their great therapeutic potential. This year we published a study of body composition PET/CT parameters that serve as predictors of monoclonal gammopathy of undetermined significance (MGUS) progression to MM(Veld J, O'Donnell EK, Reagan MR, et al. Abdominal adipose tissue in MGUS and multiple myeloma. Skeletal R
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13

Akbar, Anum, and Ume Salmah Ahmad. "IGF-1 Therapy in Children with Liver Dysfunction." Journal of Medical Research and Innovation 1, no. 1 (2017): 12–16. https://doi.org/10.5281/zenodo.322345.

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<strong>ABSTRACT</strong> Human growth and development occur as a result of numerous processes which gets initiated under the influence of endocrine hormones. Insulin-like growth factor 1 (IGF-1) plays a most pivotal role in the growth and organ development of a child. IGF-1 is a peptide that belongs to somatomedins group of hormones, also known as somatomedin C. It releases from the liver and other tissues under the influence of growth hormone (GH). The liver is the main protagonist source of IGF-1 hence any disease that can cause liver dysfunction will eventually lead to growth impairment. D
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14

"Correction for Kang et al., Prosaposin inhibits tumor metastasis via paracrine and endocrine stimulation of stromal p53 and Tsp-1." Proceedings of the National Academy of Sciences 106, no. 36 (2009): 15513. http://dx.doi.org/10.1073/pnas.0908950106.

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15

"Correction for Kang et al., Prosaposin inhibits tumor metastasis via paracrine and endocrine stimulation of stromal p53 and Tsp-1." Proceedings of the National Academy of Sciences 120, no. 51 (2023). http://dx.doi.org/10.1073/pnas.2320128120.

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16

van Tienhoven, René, Maria J. L. Kracht, Arno R. van der Slik, et al. "Presence of immunogenic alternatively spliced insulin gene product in human pancreatic delta cells." Diabetologia, March 8, 2023. http://dx.doi.org/10.1007/s00125-023-05882-y.

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Abstract Aims/hypothesis Transcriptome analyses revealed insulin-gene-derived transcripts in non-beta endocrine islet cells. We studied alternative splicing of human INS mRNA in pancreatic islets. Methods Alternative splicing of insulin pre-mRNA was determined by PCR analysis performed on human islet RNA and single-cell RNA-seq analysis. Antisera were generated to detect insulin variants in human pancreatic tissue using immunohistochemistry, electron microscopy and single-cell western blot to confirm the expression of insulin variants. Cytotoxic T lymphocyte (CTL) activation was determined by
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17

Rocha, Gabriel Reis, and Fabrício Freire de Melo. "Glucagon-like peptide-1 and impaired counterregulatory responses to hypoglycemia in type 1 diabetes." World Journal of Diabetes 16, no. 2 (2025). https://doi.org/10.4239/wjd.v16.i2.99928.

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This letter comments on a study by Jin et al , published recently in the World Journal of Diabetes . Hypoglycemia is a significant complication of diabetes, with primary defense mechanisms involving the stimulation of glucagon secretion in α-cells and the inhibition of insulin secretion in pancreatic β-cells, which are often compromised in type 1 diabetes mellitus (T1DM) and advanced type 2 diabetes mellitus. Recurrent hypoglycemia predisposes the development of impaired hypoglycemia awareness, a condition underpinned by complex pathophysiological processes, encompassing central nervous system
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18

Cherif, Alhaji, and Peter Kotanko. "P0872EFFECT OF PARATHYROID HORMONE OSCILLATIONS ON BONE HEALTH: FROM OSTEO-ANABOLISM TO CATABOLISM." Nephrology Dialysis Transplantation 35, Supplement_3 (2020). http://dx.doi.org/10.1093/ndt/gfaa143.p0872.

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Abstract Background and Aims In patients with chronic kidney disease or primary hyperparathyroidism, chronically elevated parathyroid hormones (PTH) levels exert catabolic effects on the bone. In contrast, PTH oscillations (as seen in healthy subjects) or daily application of teriparatide (a form of PTH consisting of the N-terminal 34 amino acids; it is used to treat osteoporosis) promote bone formation. These differential responses have important clinical and therapeutic implications. Although the anabolic effects of PTH (and teriparatide) cycling are widely accepted, the underlying osteo-ana
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19

Gruber, Sven, Cong Tang, Mesut Berber, et al. "SAT-LB23 Paraneoplastic Hypercalcemia in a PTH Producing Adrenocortical Carcinoma - a Rare and Deadly Condition." Journal of the Endocrine Society 4, Supplement_1 (2020). http://dx.doi.org/10.1210/jendso/bvaa046.2284.

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Abstract Background: Hypercalcemia is a commonly encountered paraneoplastic manifestation of certain cancers with or without endocrine differentiation. However, the association between adrenocortical carcinoma (ACC) with paraneoplastic hypercalcemia is very rare, and therefore little is known about the cause and its relevance in the disease. Clinical Case: A 40-year-old woman presented in the hospital with a 5-month history of progressive flank pain with unintentional weight loss of 6 kg. MRI revealed a mass of 9x8.1x4.8 cm of the right adrenal gland with inhomogeneous contrast enhancement. Bi
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