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1

Gao, Rong, Sophie Bouillet, and Ann M. Stock. "Structural Basis of Response Regulator Function." Annual Review of Microbiology 73, no. 1 (2019): 175–97. http://dx.doi.org/10.1146/annurev-micro-020518-115931.

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Response regulators function as the output components of two-component systems, which couple the sensing of environmental stimuli to adaptive responses. Response regulators typically contain conserved receiver (REC) domains that function as phosphorylation-regulated switches to control the activities of effector domains that elicit output responses. This modular design is extremely versatile, enabling different regulatory strategies tuned to the needs of individual signaling systems. This review summarizes structural features that underlie response regulator function. An abundance of atomic re
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2

He, Xiaoyuan, and Shuishu Wang. "Structural basis of DNA sequence recognition by the response regulator PhoP." Acta Crystallographica Section A Foundations and Advances 70, a1 (2014): C1409. http://dx.doi.org/10.1107/s2053273314085908.

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The PhoP-PhoR two-component system plays a key role in regulating virulence of Mycobacterium tuberculosis. The response regulator PhoP is a transcription regulator, and it regulates expression of more than 100 genes. PhoP belongs to the OmpR/PhoB subfamily of response regulators. Despite extensive research in recent years, the molecular mechanism of DNA sequence recognition by this large subfamily of response regulators is not fully understood, especially the role of the N-terminal regulatory domain on DNA binding of the effector domain. Here we present a crystal structure of the full-length P
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Sein-Echaluce, Violeta C., María Carmen Pallarés, Anabel Lostao, et al. "Molecular basis for the integration of environmental signals by FurB from Anabaena sp. PCC 7120." Biochemical Journal 475, no. 1 (2018): 151–68. http://dx.doi.org/10.1042/bcj20170692.

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FUR (Ferric uptake regulator) proteins are among the most important families of transcriptional regulators in prokaryotes, often behaving as global regulators. In the cyanobacterium Anabaena PCC 7120, FurB (Zur, Zinc uptake regulator) controls zinc and redox homeostasis through the repression of target genes in a zinc-dependent manner. In vitro, non-specific binding of FurB to DNA elicits protection against oxidative damage and avoids cleavage by deoxyribonuclease I. The present study provides, for the first time, evidence of the influence of redox environment in the interaction of FurB with r
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Moon, Seongin, Seok-Jun Seo, Won-Myung Chong, Gil-Sung You, Jeong-Hoe Ku, and Ho-Dong Kim. "ICONE23-1111 REGULATORY REQUIREMENTS FOR PYROPROCESSING FACILITY SAFETY BASIS." Proceedings of the International Conference on Nuclear Engineering (ICONE) 2015.23 (2015): _ICONE23–1—_ICONE23–1. http://dx.doi.org/10.1299/jsmeicone.2015.23._icone23-1_60.

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5

Bereslavska, Olena, and Yana Pіdsosonna. "INSTITUTIONAL BASIS OF CRYPTOASSETS’ REGULATION." Scientific Notes of Ostroh Academy National University, "Economics" Series 1, no. 32(60) (2024): 62–68. http://dx.doi.org/10.25264/2311-5149-2024-32(60)-62-68.

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The article delves into the institutional underpinnings of cryptoasset regulation, asserting that institutional relations and connections among entities extend beyond formal and informal norms and rules. These are complemented by the formation of relevant institutions and organizational relations between them, thereby shaping the institutional environment. This environment consists of the legislative and regulatory framework and the socio-economic mechanisms for regulation, all aimed at achieving collective benefits. The proposal is to view the institutional and economic relations in cryptoass
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Liu, Fenmei, Zihui Su, Peng Chen, et al. "Structural basis for zinc-induced activation of a zinc uptake transcriptional regulator." Nucleic Acids Research 49, no. 11 (2021): 6511–28. http://dx.doi.org/10.1093/nar/gkab432.

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Abstract The zinc uptake regulator (Zur) is a member of the Fur (ferric uptake regulator) family transcriptional regulators that plays important roles in zinc homeostasis and virulence of bacteria. Upon zinc perception, Zur binds to the promoters of zinc responsive genes and controls their transcription. However, the mechanism underlying zinc-mediated Zur activation remains unclear. Here we report a 2.2-Å crystal structure of apo Zur from the phytopathogen Xanthomonas campestris pv. campestris (XcZur), which reveals the molecular mechanism that XcZur exists in a closed inactive state before re
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Gribaldo, Laura. "Haematotoxicology: Scientific Basis and Regulatory Aspects." Alternatives to Laboratory Animals 30, no. 2_suppl (2002): 111–13. http://dx.doi.org/10.1177/026119290203002s17.

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Haematopoietic tissues are the targets of numerous xenobiotics. The purpose of in vitro haematotoxicology is the prediction of adverse haematological effects from toxicants on human haematopoietic targets under controlled experimental conditions in the laboratory. Building on its foundations in experimental haematology and the wealth of haematotoxicological data found in experimental oncology, this field of alternatives toxicology has developed rapidly during the past decade. Preclinical and clinical drug development for anti-cancer drugs differs from that for other pharmaceuticals, because of
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ØYEHAUG, LEIV, ERIK PLAHTE, DAG I. VÅGE, and STIG W. OMHOLT. "The Regulatory Basis of Melanogenic Switching." Journal of Theoretical Biology 215, no. 4 (2002): 449–68. http://dx.doi.org/10.1006/jtbi.2001.2521.

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9

Viatkin, Konstantyn. "REGULATORY AND LEGAL BASIS OF TERRITORIAL DEVELOPMENT." Urban development and spatial planning, no. 72 (February 21, 2020): 30–40. http://dx.doi.org/10.32347/2076-815x.2020.72.30-40.

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10

Xu, Q., A. M. Deacon, and I. A. Wilson. "Structural basis of regulatory inactivation of DnaA." Acta Crystallographica Section A Foundations of Crystallography 64, a1 (2008): C334. http://dx.doi.org/10.1107/s0108767308089320.

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11

Jurić, Zlatko, and Lidija Bencetić. "The Directive Regulatory Basis of Zagreb 1953." Journal of contemporary history 55, no. 3 (2023): 445–67. http://dx.doi.org/10.22586/csp.v55i3.28598.

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Prijedlog Direktivne regulatorne osnove Zagreba iz 1953. jedan je od najiščekivanijih dokumenata grada Zagreba u poratnom razdoblju. Njegova su rješenja trebala utjecati na svakodnevni život građana, od prometnih rješenja, pozicioniranja industrije odnosno radnih mjesta, do lokacija stanovanja i rekreacije. O urbanističkom se prijedlogu raspravljalo u zatvorenim krugovima Narodnoga odbora grada Zagreba, iz kojih su onda informacije puštane u javnost te su objavljivane u sklopu javne rasprave. Javna se rasprava sastoji od potpisanih i nepotpisanih članaka u kojima se izvještava i/ili komentira
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Pacheco, Aline, Claudia Musa Fay, Henrique Helms, and Matheus Dall Agnol Redel. "Guidelines provided by aviation regulatory agencies and organizations during the H1N1 and COVID-19 outbreaks: a comparative analisys." Núcleo do Conhecimento 07, no. 10 (2021): 148–78. https://doi.org/10.32749/nucleodoconhecimento.com.br/health/regulatory-agencies.

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Aviation has emerged as an additional and quicker vector for infectious diseases. Therefore, preparedness plans are put together to assist the public health and aviation sectors in a pandemic. This paper went through these preparedness plans, as well as the guidelines issued during two events, the H1N1 and COVID-19 pandemics, so to study, understand, assess and compare them. The method used was a thorough theoretical review supported by specific research questions, which are the basis for the analysis and discussion. The examination reveals consistent data which can work as a basis for measure
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13

Gerlach, Johannes M., and Daniel Rugilo. "The Predicament of FinTechs in the Environment of Traditional Banking Sector Regulation – An Analysis of Regulatory Sandboxes as a Possible Solution." Credit and Capital Markets – Kredit und Kapital: Volume 52, Issue 3 52, no. 3 (2019): 323–73. http://dx.doi.org/10.3790/ccm.52.3.323.

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Abstract Recently, “Financial Technology-companies” (FinTechs) are increasingly changing the financial services industry worldwide and impose considerable challenges for regulators tasked to solve the arising trade-off between sound regulation and innovation support. In this regard, regulatory sandboxes, which were recently introduced in several jurisdictions, provide a promising solution, as they imply a liberalization of regulatory requirements in order to enable FinTechs to test their innovative services. However, we observe that no comparable initiative exists in Germany, even though the G
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V., Ya. Romashko, M. Batrak L., and O. Abakumova O. "REGULATORY CHARACTERISTICS OF THE STEP-DOWN SWITCHING REGULATOR WHICH CHARGES THE BATTERY FROM THE SOLAR BATTERY." Electrical engineering & electromechanics, no. 2 (April 16, 2020): 64–67. https://doi.org/10.20998/2074-272X.2020.2.10.

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<strong><em>Problem.</em></strong><em>&nbsp;An important element of autonomous power sources, built on the basis of solar batteries, is a battery, operating in a buffer mode. To extend the period of its use, it is necessary to ensure the appropriate modes of its charging and discharging, by regulating the charging and discharge currents. To ensure that maximum power can be transferred to the load in various operating modes, a matching switching regulator is included between the solar battery and the load. In the case of its application, it becomes possible to simultaneously regulate the chargi
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15

Maume, Philipp. "Reducing Legal Uncertainty and Regulatory Arbitrage for Robo-Advice." European Company and Financial Law Review 16, no. 5 (2019): 622–51. http://dx.doi.org/10.1515/ecfr-2019-0022.

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Robo-advisers are online financial adviser services that use algorithms to create investment recommendations without human input. They deliver advice at low costs and they are growing in popularity. However, the nature of the interaction between client and machine raises many legal questions under the applicable EU regulation. This article argues that robo-advisers provide investment advice within the meaning of the Second Markets in Financial Instruments Directive (MiFiD2). They are subject to authorisation by the national regulator and ongoing conduct requirements. It might be tempting to in
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Tkachuk, A., O. Bezvesilna, I. Kryzhanivska, and M. Bogdanovsky. "FEATURES OF CONTROLLING AN ASTATIC OBJECT OF THE THIRD ORDER." Scientific heritage, no. 142 (August 7, 2024): 58–61. https://doi.org/10.5281/zenodo.13252977.

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The article examines the process of designing automatic control systems and analyzes its main stages. The most common regulatory laws and regulators built on their basis are described. The process of selecting a regulator and the method of calculating its setting parameters for controlling a third-order astatic object with an order of astatism equal to one are considered. It is shown that a high-quality control process is ensured by using the proportional-differential control law.
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17

Hanna, Razumova. "Empirical experience as a basis for managing regulatory policy changes." Economic journal Odessa polytechnic university 2, no. 8 (2019): 42–49. https://doi.org/10.5281/zenodo.3593074.

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The study allows creating a basic approach to the management of changes in regulatory policy based on empirical experience. The application of this approach allows systematizing the experience of improvement of regulatory policy in many countries and providing methodological support for change management of regulatory policy based on the best practices of world-leading countries. The given approach is oriented to the amelioration of the base cycle with the aim of its harmonization with current and promising conditions, which generate the impulse to progressive changes, the logical result of wh
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18

Dymke, N. "Radiological basis for the determination of exemption levels." Kerntechnik 67, no. 1 (2002): 13–17. http://dx.doi.org/10.1515/kern-2002-0006.

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Abstract The Radiation Protection Ordinance implements a recommendation developed by the International Commission on Radiological Protection on terms of granting a practice to be carried out without reporting and prior authorisation, i. e. on conditions of exemption of justified practices from regulatory control. According to this recommendation, a practice may be exempted from regulatory control, if the radiological risk associated with the practice is, under normal conditions as well as in diverging situations, sufficiently low as not to warrant regulatory concern, and there are no reasonabl
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19

Bakhromovna, Suyunova Kamilla. "Conceptual Basis of Regulatory and Support Policy of Tourism by the Side of Government." Journal of Advanced Research in Dynamical and Control Systems 12, SP7 (2020): 2084–87. http://dx.doi.org/10.5373/jardcs/v12sp7/20202326.

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20

Tokuoka, Miki, and Yutaka Satou. "A digital twin reproducing gene regulatory network dynamics of early Ciona embryos indicates robust buffers in the network." PLOS Genetics 19, no. 9 (2023): e1010953. http://dx.doi.org/10.1371/journal.pgen.1010953.

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How gene regulatory networks (GRNs) encode gene expression dynamics and how GRNs evolve are not well understood, although these problems have been studied extensively. We created a digital twin that accurately reproduces expression dynamics of 13 genes that initiate expression in 32-cell ascidian embryos. We first showed that gene expression patterns can be manipulated according to predictions by this digital model. Next, to simulate GRN rewiring, we changed regulatory functions that represented their regulatory mechanisms in the digital twin, and found that in 55 of 100 cases, removal of a si
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21

Ugur, Mehmet. "Regulatory Quality and Performance in EU Network Industries: Evidence on Telecommunications, Gas and Electricity." Journal of Public Policy 29, no. 3 (2009): 347–70. http://dx.doi.org/10.1017/s0143814x09990109.

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ABSTRACTThis article provides empirical evidence on ex ante and ex post indicators of regulatory quality and the relationship between those indicators and market performance in liberalised EU-15 network industries. It finds a low level of regulatory independence and competence, a high level of cross-country variations in regulatory quality, and widespread absence of correlation between ex ante regulatory quality and ex post performance indicators. On the basis of these findings, it suggests that the design of national regulatory agencies (NRAs) in Europe is not optimal and may be conducive to
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22

Wang, Meixian, Jiahao Wang, Ayinuer Yasen, Bingyan Fan, J. Joe Hull, and Xingjia Shen. "Determination of Key Components in the Bombyx mori p53 Apoptosis Regulation Network Using Y2H-Seq." Insects 14, no. 4 (2023): 362. http://dx.doi.org/10.3390/insects14040362.

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The apoptosis pathway is highly conserved between invertebrates and mammals. Although genes encoding the classical apoptosis pathway can be found in the silkworm genome, the regulatory pathway and other apoptotic network genes have yet to be confirmed. Consequently, characterizing these genes and their underlying mechanisms could provide critical insights into the molecular basis of organ apoptosis and remodeling. A homolog of p53, a key apoptosis regulator in vertebrates, has been identified and cloned from Bombyx mori (Bmp53). This study confirmed via gene knockdown and overexpression that B
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KAMAE, Katsuhiro. "Design Basis Ground Motion Required on New Regulatory Guide." Journal of the Atomic Energy Society of Japan 55, no. 6 (2013): 326–31. http://dx.doi.org/10.3327/jaesjb.55.6_326.

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Malyga, Viktoriya. "STRATEGY AS A BASIS FOR THE IMPLEMENTATIONSTATE REGULATORY POLICY." Visnyk of the Lviv University. Series Law, no. 61 (September 10, 2015): 30–36. http://dx.doi.org/10.30970/vla.2015.61.193.

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25

Calvo, B., and L. Zuñiga. "Regulatory basis of biosimilar medicinal products: Need for harmonization." Pharmaceuticals, Policy and Law 12, no. 3,4 (2010): 205–15. http://dx.doi.org/10.3233/ppl-2010-0299.

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26

Gold, Matthew G., Birgitte Lygren, Pawel Dokurno, et al. "Molecular Basis of AKAP Specificity for PKA Regulatory Subunits." Molecular Cell 24, no. 3 (2006): 383–95. http://dx.doi.org/10.1016/j.molcel.2006.09.006.

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27

Xu, Qingping, Daniel McMullan, Polat Abdubek, et al. "A Structural Basis for the Regulatory Inactivation of DnaA." Journal of Molecular Biology 385, no. 2 (2009): 368–80. http://dx.doi.org/10.1016/j.jmb.2008.10.059.

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28

TKACHUK, Iryna. "Methodological basis of state regulation of civil society finances." Economics. Finances. Law, no. 9/1 (September 25, 2020): 19–26. http://dx.doi.org/10.37634/efp.2020.9(1).4.

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Civil society organizations can play an important role in the process of solving the significant social and economic problems at both the local and national levels. However, their contribution depends significantly on the environment in which they are functioning and on the current state of organizing of their finances. The current state of organizing and functioning of civil society finances depends on the state regulation process in this sphere. It is important that the state regulatory activity is carried out on the certain methodology. This article is devoted to the study of the basics of
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Busch, Andreas, Jesús Lacal, Hortencia Silva-Jímenez, Tino Krell, and Juan L. Ramos. "Catabolite Repression of the TodS/TodT Two-Component System and Effector-Dependent Transphosphorylation of TodT as the Basis for Toluene Dioxygenase Catabolic Pathway Control." Journal of Bacteriology 192, no. 16 (2010): 4246–50. http://dx.doi.org/10.1128/jb.00379-10.

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ABSTRACT The TodS/TodT two-component system of Pseudomonas putida regulates the expression of the toluene dioxygenase (tod) operon for the metabolism of toluene, benzene, and ethylbenzene. The sensor kinase TodS has a complex domain arrangement containing two functional modules, each harboring a sensor and an autokinase domain separated by a receiver domain. The TodT protein is the cognate response regulator that activates transcription of the toluene dioxygenase (TOD) pathway genes at the P todX promoter. We report in this study that the todST operon is transcribed from a main promoter and th
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Jensen, Jaime L., Beau D. Jernberg, Sangita C. Sinha, and Christopher L. Colbert. "Structural basis of cell-surface signaling by a conserved sigma regulator in Gram-negative bacteria." Journal of Biological Chemistry 295, no. 17 (2020): 5795–806. http://dx.doi.org/10.1074/jbc.ra119.010697.

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Cell-surface signaling (CSS) in Gram-negative bacteria involves highly conserved regulatory pathways that optimize gene expression by transducing extracellular environmental signals to the cytoplasm via inner-membrane sigma regulators. The molecular details of ferric siderophore-mediated activation of the iron import machinery through a sigma regulator are unclear. Here, we present the 1.56 Å resolution structure of the periplasmic complex of the C-terminal CSS domain (CCSSD) of PupR, the sigma regulator in the Pseudomonas capeferrum pseudobactin BN7/8 transport system, and the N-terminal sign
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de Carvalho, Bruno Eustaquio, Rui Cunha Marques, and Oscar Cordeiro Netto. "Rethinking Brasília's water services: ‘new targets’ using the regulatory impact assessment (RIA) tool." Journal of Water, Sanitation and Hygiene for Development 9, no. 1 (2019): 7–18. http://dx.doi.org/10.2166/washdev.2019.088.

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Abstract This paper suggests a regulatory impact assessment (RIA) to evaluate the potential effects of ‘Resolution law no. 08/2016’ in the Brasília water sector under different perspectives: customers, regulators and local providers. Currently, political/rational and expert/politician terms are not considered integrated parts of the decision process, which could create a non-desirable impact on utility services. Thus, by using the RIA policy tool, regulators would be able to develop a basis for making good decisions rooted in evidence. From that point of view, RIA was set in order to provide t
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Fegan, Regina M., Michael T. Olexa, and Robert J. McGovern. "Protecting Agriculture: The Legal Basis of Regulatory Action in Florida." Plant Disease 88, no. 9 (2004): 1040–43. http://dx.doi.org/10.1094/pdis.2004.88.9.1040.

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The Division of Plant Industry of the Department of Agriculture and Consumer Services of Florida is empowered to protect the state's agriculture from both introduction and intrastate movement of pests. This responsibility is shared by similar regulatory agencies of the federal government and other states. The legal basis of such regulatory action, police power and eminent domain, is reviewed. The regulatory processes by the State of Florida of two important citrus pests, the burrowing nematode and Asiatic citrus canker, are presented. It was concluded that Florida's regulatory power to take pr
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Li, Zhen, Wanxin Li, Jinlian Lu, Ziqiu Liu, Xiangmin Lin, and Yanling Liu. "Quantitative Proteomics Analysis Reveals the Effect of a MarR Family Transcriptional Regulator AHA_2124 on Aeromonas hydrophila." Biology 12, no. 12 (2023): 1473. http://dx.doi.org/10.3390/biology12121473.

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The transcriptional regulators of the MarR family play an important role in diverse bacterial physiologic functions, whereas their effect and intrinsic regulatory mechanism on the aquatic pathogenic bacterium Aeromonas hydrophila are, clearly, still unknown. In this study, we firstly constructed a deletion strain of AHA_2124 (ΔAHA_2124) of a MarR family transcriptional regulator in Aeromonas hydrophila ATCC 7966 (wild type), and found that the deletion of AHA_2124 caused significantly enhanced hemolytic activity, extracellular protease activity, and motility when compared with the wild type. T
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Voynovskiy, A. E., and A. E. Efanov. "Analysis of legislative basis for medical rehabilitation in Russia." Rehabilitology 2, no. 1 (2024): 115–21. http://dx.doi.org/10.17749/2949-5873/rehabil.2024.15.

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Background. In recent years, there have been significant changes in the regulatory documentation related to medical rehabilitation, caused by the need to consolidate the principles for rehabilitation of patients in post-COVID period and standardize the procedures used for it. Therefore, it is important to analyze the existing regulatory framework and the proposed changes that will come into force in the near future.Objective: to assess the regulatory legal acts governing the provision of medical rehabilitation in Russia.Material and methods. Regulatory legal acts and their drafts were obtained
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Zhou, Huaijun. "97 Dissection of Evolution of Cis-Regulatory Elements and Its Application on Genetic Control of Complex Traits in Farm Animals." Journal of Animal Science 101, Supplement_3 (2023): 51–52. http://dx.doi.org/10.1093/jas/skad281.063.

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Abstract Functional Annotation of Animal Genomes (FAANG) has made significant progress on the improvement of the annotation of the functional elements, particularly non-coding regions in farm animal genomes. Different epigenomes including ChIP-seq for 4 histone marks, ATAC-seq, CTCF-seq, RNA-seq, and Hi-C across different tissues in different animal species were generated. Thousands of cis-regulatory elements including promoters and enhancers across different tissues in different species were identified and annotated. A comprehensive characterization and comparison of cis-regulatory elements a
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Giardina, Giorgio, Nicoletta Castiglione, Manuela Caruso, Francesca Cutruzzolà, and Serena Rinaldo. "The Pseudomonas aeruginosa DNR transcription factor: light and shade of nitric oxide-sensing mechanisms." Biochemical Society Transactions 39, no. 1 (2011): 294–98. http://dx.doi.org/10.1042/bst0390294.

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In response to environmental conditions, NO (nitric oxide) induces global changes in the cellular metabolism of Pseudomonas aeruginosa, which are strictly related to pathogenesis. In particular, at low oxygen tensions and in the presence of NO the denitrification alternative respiration is activated by a key regulator: DNR (dissimilative nitrate respiration regulator). DNR belongs to the CRP (cAMP receptor protein)–FNR (fumarate and nitrate reductase regulatory protein) superfamily of bacterial transcription factors. These regulators are involved in many different pathways and distinct activat
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Chambers, Rebecca L., and John C. McDermott. "Molecular Basis of Skeletal Muscle Regeneration." Canadian Journal of Applied Physiology 21, no. 3 (1996): 155–84. http://dx.doi.org/10.1139/h96-014.

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Skeletal muscle regeneration is a vital process with important implications for various muscle myopathies and adaptations to physiological overload. Few of the molecular regulatory proteins controlling this process have so far been identified. Several growth factors have defined effects on myogenic precursor cells and appear to also be involved during regeneration. In addition, factors that may be released by cells of the immune system may activate satellite cells during regeneration. Many of these growth factors are associated with signalling cascades which transmit information to the nucleus
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Zhao, Jan Bin, and Jie Tian. "Analysis of Roles about Participating Subjects of Regulatory Detailed Planning’s Formulation." Advanced Materials Research 368-373 (October 2011): 1902–5. http://dx.doi.org/10.4028/www.scientific.net/amr.368-373.1902.

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In regulatory planning’s formulation and implementation of China, there are four participating subjects, namely managers, planners, developers and users. These four subjects represent different social stratifications and interest groups. They play diverse roles in the stage of regulatory planning’s formulation. This paper bases on the demands of participating subjects, analyses the relevant problems, dissects different roles of them, provides theoretical basis for the improvement of regulatory planning’s formulation and explores the relevant practice.
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M. M., Proshunin. "Legal Issues of Annulment of Licenses of Professional Participant on Securities Market." Rossijskoe pravosudie, no. 8 (July 16, 2021): 91–95. http://dx.doi.org/10.37399/issn2072-909x.2021.8.91-95.

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The article reveals the legal issues of annulment of licenses of professional participant on securities market on the basis of the application submitted by the owner of the securities market license. The author considers the main provisions of the procedure of annulment of the securities market licenses and suggests some directions of development of regulations of annulment of securities market licenses in order to ensure the effective collaboration between the professional market participant on securities market and the Bank of Russia. In order to optimize the existing procedure the author su
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Pradhan, Pitabas. "Watching the Watchdogs-Moral Basis for a Broadcast Regulatory Authority." Media Watch 1, no. 1 (2010): 7–15. http://dx.doi.org/10.1177/0976091120100102.

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Katti, Sachin S., Inna V. Krieger, James C. Sacchettini, and Tatyana I. Igumenova. "Structural basis of agonist capture by PKC-regulatory C1 domain." Biophysical Journal 121, no. 3 (2022): 224a. http://dx.doi.org/10.1016/j.bpj.2021.11.1605.

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Tiruttani Subhramanyam, Udaya K., Jan Kubicek, Ulf B. Eidhoff, and Joerg Labahn. "Structural basis for the regulatory interactions of proapoptotic Par-4." Cell Death & Differentiation 24, no. 9 (2017): 1540–47. http://dx.doi.org/10.1038/cdd.2017.76.

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Bhasin, Naina, Shane R. Cunha, Malkanthi Mudannayake, Marisa S. Gigena, Terry B. Rogers та Peter J. Mohler. "Molecular basis for PP2A regulatory subunit B56α targeting in cardiomyocytes". American Journal of Physiology-Heart and Circulatory Physiology 293, № 1 (2007): H109—H119. http://dx.doi.org/10.1152/ajpheart.00059.2007.

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Protein phosphatase 2A (PP2A) is a multifunctional protein phosphatase with critical roles in excitable cell signaling. In the heart, PP2A function is linked with modulation of β-adrenergic signaling and has been suggested to regulate key ion channels and transporters including Na/Ca exchanger, ryanodine receptor, inositol 1,4,5-trisphosphate receptor, and Na/K ATPase. Although many of the functional roles and molecular targets for PP2A in heart are known, little is established regarding the cellular pathways that localize specific PP2A isoform activities to subcellular sites. We report that t
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Naranjo, Santiago, Justin D. Smith, Carlo G. Artieri, et al. "Dissecting the Genetic Basis of a Complex cis-Regulatory Adaptation." PLOS Genetics 11, no. 12 (2015): e1005751. http://dx.doi.org/10.1371/journal.pgen.1005751.

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Howard, B. A., M. B. Crawford, D. A. Galson, and M. G. Marietta. "Regulatory basis for the Waste Isolation Pilot Plant performance assessment." Reliability Engineering & System Safety 69, no. 1-3 (2000): 109–27. http://dx.doi.org/10.1016/s0951-8320(00)00028-4.

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LOVINSKA, Ljudmyla, Yana OLIYNYK, and Tetiana BONDAR. "Regulatory and legal basis for enterprise management reporting in Ukraine." Fìnansi Ukraïni 2018, no. 6 (2018): 19–44. http://dx.doi.org/10.33763/finukr2018.06.019.

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Kast, David J. E., Yadaiah Madasu, Malgorzata Boczkowska, Grzegorz Rebowski, and Roberto Dominguez. "Structural Basis for Activation of the Cytoskeleton Regulatory Protein IRSp53." Biophysical Journal 102, no. 3 (2012): 697a. http://dx.doi.org/10.1016/j.bpj.2011.11.3785.

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Kalaianov, D. P., and M. A. Slobodianiuk. "Regulatory and legal basis for disciplinary responsibility of police officers." Legal Novels, no. 19 (2023): 470–75. http://dx.doi.org/10.32782/ln.2023.19.63.

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Shcharbakova, K. N. "Legal and regulatory basis for organizing work within suicide prevention." Health and Ecology Issues 21, no. 4 (2025): 135–41. https://doi.org/10.51523/2708-6011.2024-21-4-14.

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Objective. To study the legal and regulatory basis of the Republic of Belarus on work organization of institutions implementing preventive measures within suicide prevention.Materials and methods. The legislative framework of the Republic of Belarus in the field of healthcare on issues of organizing the work of institutions implementing preventive measures in the context of suicide prevention was analyzed. The features of inter-institutional interaction of structures implementing preventive measures to reduce suicide risks were selected in laws and regulations.Results. Inter-institutional leve
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GULYAMOV, Said, and Ilyosbek ODILKHUJAEV. "LEGAL BASIS FOR INFORMATION SECURITY RISK MANAGEMENT IN THE NOTARIAL SECTOR." Young Scholar's Academic Journal III, no. 1 (2024): 6–11. https://doi.org/10.5281/zenodo.10616226.

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<em>Information security risks threaten the integrity of notarial services in an increasingly digital age. Using a doctrinal and comparative methodology, this study analyses the regulatory framework for notarial cyber risk management in the United States and internationally. Key findings show that existing regulations lack harmonized, tailored standards and oversight for notaries. The introduction of nationwide requirements, audits, training programmes and sector-specific regulations could significantly improve risk management. Non-regulatory initiatives such as education and public-private co
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