Academic literature on the topic 'Regulatory small RNA'

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Journal articles on the topic "Regulatory small RNA"

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Babski, Julia, Lisa-Katharina Maier, Ruth Heyer, et al. "Small regulatory RNAs in Archaea." RNA Biology 11, no. 5 (2014): 484–93. http://dx.doi.org/10.4161/rna.28452.

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Sonnleitner, Elisabeth, Alessandra Romeo, and Udo Bläsi. "Small regulatory RNAs inPseudomonas aeruginosa." RNA Biology 9, no. 4 (2012): 364–71. http://dx.doi.org/10.4161/rna.19231.

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Li, Siqi, Zhengping Xu, and Jinghao Sheng. "tRNA-Derived Small RNA: A Novel Regulatory Small Non-Coding RNA." Genes 9, no. 5 (2018): 246. http://dx.doi.org/10.3390/genes9050246.

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Klein, Gracjana, and Satish Raina. "Small regulatory bacterial RNAs regulating the envelope stress response." Biochemical Society Transactions 45, no. 2 (2017): 417–25. http://dx.doi.org/10.1042/bst20160367.

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Most bacteria encode a large repertoire of RNA-based regulatory mechanisms. Recent discoveries have revealed that the expression of many genes is controlled by a plethora of base-pairing noncoding small regulatory RNAs (sRNAs), regulatory RNA-binding proteins and RNA-degrading enzymes. Some of these RNA-based regulated processes respond to stress conditions and are involved in the maintenance of cellular homeostasis. They achieve it by either direct posttranscriptional repression of several mRNAs, including blocking access to ribosome and/or directing them to RNA degradation when the synthesis
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Michaux, Charlotte, Nicolas Verneuil, Axel Hartke, and Jean-Christophe Giard. "Physiological roles of small RNA molecules." Microbiology 160, no. 6 (2014): 1007–19. http://dx.doi.org/10.1099/mic.0.076208-0.

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Unlike proteins, RNA molecules have emerged lately as key players in regulation in bacteria. Most reviews hitherto focused on the experimental and/or in silico methods used to identify genes encoding small RNAs (sRNAs) or on the diverse mechanisms of these RNA regulators to modulate expression of their targets. However, less is known about their biological functions and their implications in various physiological responses. This review aims to compile what is known presently about the diverse roles of sRNA transcripts in the regulation of metabolic processes, in different growth conditions, in
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Huang, Yong, Ji Liang Zhang, Xue Li Yu, Ting Sheng Xu, Zhan Bin Wang, and Xiang Chao Cheng. "Molecular functions of small regulatory noncoding RNA." Biochemistry (Moscow) 78, no. 3 (2013): 221–30. http://dx.doi.org/10.1134/s0006297913030024.

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Brantl, Sabine, and Reinhold Brückner. "Small regulatory RNAs from low-GC Gram-positive bacteria." RNA Biology 11, no. 5 (2014): 443–56. http://dx.doi.org/10.4161/rna.28036.

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Carrier, Marie-Claude, David Lalaouna, and Eric Massé. "Broadening the Definition of Bacterial Small RNAs: Characteristics and Mechanisms of Action." Annual Review of Microbiology 72, no. 1 (2018): 141–61. http://dx.doi.org/10.1146/annurev-micro-090817-062607.

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The first report of trans-acting RNA-based regulation in bacterial cells dates back to 1984. Subsequent studies in diverse bacteria unraveled shared properties of trans-acting small regulatory RNAs, forming a clear definition of these molecules. These shared characteristics have been used extensively to identify new small RNAs (sRNAs) and their interactomes. Recently however, emerging technologies able to resolve RNA-RNA interactions have identified new types of regulatory RNAs. In this review, we present a broader definition of trans-acting sRNA regulators and discuss their newly discovered i
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Li, Lei, Dandan Huang, Man Kit Cheung, Wenyan Nong, Qianli Huang, and Hoi Shan Kwan. "BSRD: a repository for bacterial small regulatory RNA." Nucleic Acids Research 41, no. D1 (2012): D233—D238. http://dx.doi.org/10.1093/nar/gks1264.

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Okamura, K., N. Robine, Y. Liu, Q. Liu, and E. C. Lai. "R2D2 Organizes Small Regulatory RNA Pathways in Drosophila." Molecular and Cellular Biology 31, no. 4 (2010): 884–96. http://dx.doi.org/10.1128/mcb.01141-10.

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Dissertations / Theses on the topic "Regulatory small RNA"

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Santos, Bruno Acácio de Castro Moreira dos. "Small RNAs in gene regulatory networks." Thesis, University of Cambridge, 2015. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708543.

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Le, Rhun Anaïs. "Multifaceted RNA-mediated regulatory mechanisms in Streptococcus pyogenes." Doctoral thesis, Umeå universitet, Molekylär Infektionsmedicin, Sverige (MIMS), 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-111090.

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Bacterial pathogens rely on precise regulation of gene expression to coordinate host infection processes and resist invasion by mobile genetic elements. An interconnected network of protein and RNA regulators dynamically controls the expression of virulence factors using a variety of mechanisms. In this thesis, the role of selected regulators, belonging to the class of small RNAs (sRNAs), is investigated. Streptococcus pyogenes is a pathogen responsible for a wide range of human diseases. Genome-wide screenings have indicated that S. pyogenes encodes numerous sRNAs, yet only a limited number h
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Choy, Yee-wai Elizabeth. "A study of Epstein-Barr virus-encoded small regulatory RNAs." Click to view the E-thesis via HKUTO, 2007. http://sunzi.lib.hku.hk/HKUTO/record/B39557261.

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蔡依慧 and Yee-wai Elizabeth Choy. "A study of Epstein-Barr virus-encoded small regulatory RNAs." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B39557261.

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Simkin, Alfred T. "Evolutionary Approaches to the Study of Small Noncoding Regulatory RNA Pathways: A Dissertation." eScholarship@UMMS, 2007. http://escholarship.umassmed.edu/gsbs_diss/721.

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Short noncoding RNAs play roles in regulating nearly every biological process, in nearly every organism, yet the exact function and importance of these molecules remains a subject of some debate. In order to gain a better understanding of the contexts in which these regulators have evolved, I have undertaken a variety of approaches to study the evolutionary history of the components that make up these pathways, in the form of two main research efforts. In the first chapter, I have used a combination of population genetics and molecular evolution techniques to show that proteins involved in the
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Simkin, Alfred T. "Evolutionary Approaches to the Study of Small Noncoding Regulatory RNA Pathways: A Dissertation." eScholarship@UMMS, 2014. https://escholarship.umassmed.edu/gsbs_diss/721.

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Short noncoding RNAs play roles in regulating nearly every biological process, in nearly every organism, yet the exact function and importance of these molecules remains a subject of some debate. In order to gain a better understanding of the contexts in which these regulators have evolved, I have undertaken a variety of approaches to study the evolutionary history of the components that make up these pathways, in the form of two main research efforts. In the first chapter, I have used a combination of population genetics and molecular evolution techniques to show that proteins involved in the
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梁靄褳 and Oi-ning Leung. "Identification and characterization of E3 ubiquitin ligase SIAH1 as a regulatory target of microRNA-135a in HeLa cells." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2008. http://hub.hku.hk/bib/B40738589.

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Leung, Oi-ning. "Identification and characterization of E3 ubiquitin ligase SIAH1 as a regulatory target of microRNA-135a in HeLa cells." Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/hkuto/record/B40738589.

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Iosub, Ira Alexandra. "Role of small regulatory RNA networks in controlling adaptive responses in Escherichia coli." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/31477.

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Microorganisms are exposed to constantly changing environments, and consequently have evolved mechanisms to rapidly adapt their physiology upon stress imposition. These adaptive responses are coordinated through the rewiring of gene expression via complex networks that control the transcriptional program and the activity of post-transcriptional regulators. Although transcription factors primarily determine which genes are expressed, post-transcriptional regulation has a major role in fine-tuning the dynamics of gene expression. Post-transcriptional control is exerted by RNA-binding proteins an
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Harris, Andreas William Kisling. "The design of gene regulatory networks with feedback and small non-coding RNA." Thesis, University of Oxford, 2017. https://ora.ox.ac.uk/objects/uuid:e3a323b1-9067-415d-8728-6c70c1b6cf23.

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The objective of the field of Synthetic Biology is to implement novel functionalities in a biological context or redesign existing biological systems. To achieve this, it employs tried and tested engineering principles, such as standardisation and the design-build-test cycle. A crucial part of this process is the convergence of modelling and experiment. The aim of this thesis is to improve the design principles employed by Synthetic Biology in the context of Gene Regulatory Networks (GRNs). Small Ribonucleic Acids (sRNAs), in particular, are focussed on as a mechanism for post-transcriptional
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Books on the topic "Regulatory small RNA"

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Bruce, Stillman, Stewart, David J., Ph.D., and Cold Spring Harbor Laboratory, eds. Regulatory RNAs. Cold Spring Harbor Laboratory Press, 2006.

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Zhang, Baohong, ed. RNAi and Small Regulatory RNAs in Stem Cells. Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-7108-4.

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The RFA at 25: Needed improvements for small business regulatory relief : hearing before the Committee on Small Business, House of Representatives, One Hundred Ninth Congress, first session, Washington, DC, March 16, 2005. U.S. G.P.O., 2005.

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(Editor), Wolfgang Nellen, and Christian Hammann (Editor), eds. Small RNAs:: Analysis and Regulatory Functions (Nucleic Acids and Molecular Biology). Springer, 2005.

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RNAi and Small Regulatory RNAs in Stem Cells: Methods and Protocols. Humana, 2018.

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(Editor), Wolfgang Nellen, and Christian Hammann (Editor), eds. Small RNAs:: Analysis and Regulatory Functions (Nucleic Acids and Molecular Biology). Springer, 2007.

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Giacca, Mauro, and Borja Ibáñez. Advanced therapies to treat cardiovascular diseases: controversies and perspectives. Edited by José Maria Pérez-Pomares, Robert G. Kelly, Maurice van den Hoff, et al. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198757269.003.0028.

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There is a pressing need to develop novel therapies for myocardial infarction and heart failure, two conditions that affect over 20% of the world population. Despite important advances in achieving revascularization of the ischaemic myocardium and the usefulness of devices in assisting failing hearts, therapy for these conditions remains poor. The final extent of myocardial tissue loss after infarction is a major determinant of post-infarction mortality due to heart failure. In this chapter we review the current strategies aimed at counteracting injury due to acute myocardial ischaemia–reperfu
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Book chapters on the topic "Regulatory small RNA"

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Desnoyers, Guillaume, and Eric Massé. "Activity of Small RNAs on the Stability of Targeted mRNAs In Vivo." In Bacterial Regulatory RNA. Humana Press, 2012. http://dx.doi.org/10.1007/978-1-61779-949-5_16.

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Peng, Yi, Toby J. Soper, and Sarah A. Woodson. "RNase Footprinting of Protein Binding Sites on an mRNA Target of Small RNAs." In Bacterial Regulatory RNA. Humana Press, 2012. http://dx.doi.org/10.1007/978-1-61779-949-5_13.

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Hobbs, Errett C., and Gisela Storz. "Competition Assays Using Barcoded Deletion Strains to Gain Insight into Small RNA Function." In Bacterial Regulatory RNA. Humana Press, 2012. http://dx.doi.org/10.1007/978-1-61779-949-5_5.

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Corcoran, Colin P., Renate Rieder, Dimitri Podkaminski, Benjamin Hofmann, and Jörg Vogel. "Use of Aptamer Tagging to Identify In Vivo Protein Binding Partners of Small Regulatory RNAs." In Bacterial Regulatory RNA. Humana Press, 2012. http://dx.doi.org/10.1007/978-1-61779-949-5_11.

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Scott, Michelle S. "Diversity, Overlap, and Relationships in the Small RNA Landscape." In Regulatory RNAs. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-662-45801-3_2.

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Wong, Julia, Ignatius Pang, Marc Wilkins, and Jai J. Tree. "Systems-Level Analysis of Bacterial Regulatory Small RNA Networks." In RNA Technologies. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-92967-5_6.

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Ando, Yoshinari, A. Maxwell Burroughs, Mitsuoki Kawano, Michiel Jan Laurens de Hoon, and Yoshihide Hayashizaki. "Targeted Methods to Improve Small RNA Profiles Generated by Deep Sequencing." In Regulatory RNAs. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-662-45801-3_10.

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Schenkel, Werner, and Achim Gathmann. "Regulatory aspects of RNAi in plant production." In RNAi for plant improvement and protection. CABI, 2021. http://dx.doi.org/10.1079/9781789248890.0154.

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Abstract Technologies based on RNA interference (RNAi) may be used in plant production in different contexts. With respect to applicable regulations, a major distinction is to be made between plants producing small RNA molecules due to modifications of the genome and topically applied plant protection products (PPPs) based on double-stranded RNA (dsRNA). The first group may be further divided into those using RNAi technology to achieve changes in the plant's metabolism and those where plant-produced RNA molecules are intended to impact other organisms that interact with the plant. For PPPs, relevant aspects are whether the product contains living organisms or only purified molecules. The intended use of the product is another relevant aspect with respect to regulation. It is expected that PPPs will be among the first products utilizing the RNAi mechanism in the European Union. This chapter discusses the regulation of modified RNAi plants and the regulation of PPPs utilizing RNAi mechanisms.
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Schenkel, Werner, and Achim Gathmann. "Regulatory aspects of RNAi in plant production." In RNAi for plant improvement and protection. CABI, 2021. http://dx.doi.org/10.1079/9781789248890.0014a.

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Abstract Technologies based on RNA interference (RNAi) may be used in plant production in different contexts. With respect to applicable regulations, a major distinction is to be made between plants producing small RNA molecules due to modifications of the genome and topically applied plant protection products (PPPs) based on double-stranded RNA (dsRNA). The first group may be further divided into those using RNAi technology to achieve changes in the plant's metabolism and those where plant-produced RNA molecules are intended to impact other organisms that interact with the plant. For PPPs, relevant aspects are whether the product contains living organisms or only purified molecules. The intended use of the product is another relevant aspect with respect to regulation. It is expected that PPPs will be among the first products utilizing the RNAi mechanism in the European Union. This chapter discusses the regulation of modified RNAi plants and the regulation of PPPs utilizing RNAi mechanisms.
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Brosse, Anaïs, and Maude Guillier. "Bacterial Small RNAs in Mixed Regulatory Networks." In Regulating with RNA in Bacteria and Archaea. ASM Press, 2018. http://dx.doi.org/10.1128/9781683670247.ch26.

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Conference papers on the topic "Regulatory small RNA"

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Min Xiao and Wei Xing Zheng. "On oscillatory dynamics of small-RNAs-mediated two-gene regulatory networks." In 2013 IEEE International Symposium on Circuits and Systems (ISCAS). IEEE, 2013. http://dx.doi.org/10.1109/iscas.2013.6572209.

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BETEL, DORON, CHRISTINA LESLIE, and NIKOLAUS RAJEWSKY. "COMPUTATIONAL CHALLENGES IN THE STUDY OF SMALL REGULATORY RNAS – Session Introduction." In Proceedings of the Pacific Symposium. WORLD SCIENTIFIC, 2007. http://dx.doi.org/10.1142/9789812776136_0006.

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Le, Shu-Yun, and A. Shapiro Bruce. "Characterization of structural features for small regulatory RNAs in Escherichia coli genomes." In 2010 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). IEEE, 2010. http://dx.doi.org/10.1109/bibm.2010.5706538.

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Ramos, Christian G., Silvia A. Sousa, Andre M. Grilo, Paulo J. P. Da Costa, Joana R. Feliciano, and Jorge H. Leitao. "A RNomics-based strategy identifies regulatory small RNAs in Burkholderia cepacia complex." In 2011 1st Portuguese Meeting in Bioengineering ¿ The Challenge of the XXI Century (ENBENG). IEEE, 2011. http://dx.doi.org/10.1109/enbeng.2011.6026035.

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Reports on the topic "Regulatory small RNA"

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African Open Science Platform Part 1: Landscape Study. Academy of Science of South Africa (ASSAf), 2019. http://dx.doi.org/10.17159/assaf.2019/0047.

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This report maps the African landscape of Open Science – with a focus on Open Data as a sub-set of Open Science. Data to inform the landscape study were collected through a variety of methods, including surveys, desk research, engagement with a community of practice, networking with stakeholders, participation in conferences, case study presentations, and workshops hosted. Although the majority of African countries (35 of 54) demonstrates commitment to science through its investment in research and development (R&D), academies of science, ministries of science and technology, policies, rec
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