Relevant bibliographies by topics / Regulatory small RNA / Dissertations / Theses
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Dissertations / Theses on the topic 'Regulatory small RNA'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 February 2022

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1

Santos, Bruno Acácio de Castro Moreira dos. "Small RNAs in gene regulatory networks." Thesis, University of Cambridge, 2015. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708543.

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2

Le, Rhun Anaïs. "Multifaceted RNA-mediated regulatory mechanisms in Streptococcus pyogenes." Doctoral thesis, Umeå universitet, Molekylär Infektionsmedicin, Sverige (MIMS), 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-111090.

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Bacterial pathogens rely on precise regulation of gene expression to coordinate host infection processes and resist invasion by mobile genetic elements. An interconnected network of protein and RNA regulators dynamically controls the expression of virulence factors using a variety of mechanisms. In this thesis, the role of selected regulators, belonging to the class of small RNAs (sRNAs), is investigated. Streptococcus pyogenes is a pathogen responsible for a wide range of human diseases. Genome-wide screenings have indicated that S. pyogenes encodes numerous sRNAs, yet only a limited number h
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3

Choy, Yee-wai Elizabeth. "A study of Epstein-Barr virus-encoded small regulatory RNAs." Click to view the E-thesis via HKUTO, 2007. http://sunzi.lib.hku.hk/HKUTO/record/B39557261.

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4

蔡依慧 and Yee-wai Elizabeth Choy. "A study of Epstein-Barr virus-encoded small regulatory RNAs." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B39557261.

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5

Simkin, Alfred T. "Evolutionary Approaches to the Study of Small Noncoding Regulatory RNA Pathways: A Dissertation." eScholarship@UMMS, 2007. http://escholarship.umassmed.edu/gsbs_diss/721.

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Short noncoding RNAs play roles in regulating nearly every biological process, in nearly every organism, yet the exact function and importance of these molecules remains a subject of some debate. In order to gain a better understanding of the contexts in which these regulators have evolved, I have undertaken a variety of approaches to study the evolutionary history of the components that make up these pathways, in the form of two main research efforts. In the first chapter, I have used a combination of population genetics and molecular evolution techniques to show that proteins involved in the
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Simkin, Alfred T. "Evolutionary Approaches to the Study of Small Noncoding Regulatory RNA Pathways: A Dissertation." eScholarship@UMMS, 2014. https://escholarship.umassmed.edu/gsbs_diss/721.

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Short noncoding RNAs play roles in regulating nearly every biological process, in nearly every organism, yet the exact function and importance of these molecules remains a subject of some debate. In order to gain a better understanding of the contexts in which these regulators have evolved, I have undertaken a variety of approaches to study the evolutionary history of the components that make up these pathways, in the form of two main research efforts. In the first chapter, I have used a combination of population genetics and molecular evolution techniques to show that proteins involved in the
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7

梁靄褳 and Oi-ning Leung. "Identification and characterization of E3 ubiquitin ligase SIAH1 as a regulatory target of microRNA-135a in HeLa cells." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2008. http://hub.hku.hk/bib/B40738589.

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Leung, Oi-ning. "Identification and characterization of E3 ubiquitin ligase SIAH1 as a regulatory target of microRNA-135a in HeLa cells." Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/hkuto/record/B40738589.

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9

Iosub, Ira Alexandra. "Role of small regulatory RNA networks in controlling adaptive responses in Escherichia coli." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/31477.

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Microorganisms are exposed to constantly changing environments, and consequently have evolved mechanisms to rapidly adapt their physiology upon stress imposition. These adaptive responses are coordinated through the rewiring of gene expression via complex networks that control the transcriptional program and the activity of post-transcriptional regulators. Although transcription factors primarily determine which genes are expressed, post-transcriptional regulation has a major role in fine-tuning the dynamics of gene expression. Post-transcriptional control is exerted by RNA-binding proteins an
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10

Harris, Andreas William Kisling. "The design of gene regulatory networks with feedback and small non-coding RNA." Thesis, University of Oxford, 2017. https://ora.ox.ac.uk/objects/uuid:e3a323b1-9067-415d-8728-6c70c1b6cf23.

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The objective of the field of Synthetic Biology is to implement novel functionalities in a biological context or redesign existing biological systems. To achieve this, it employs tried and tested engineering principles, such as standardisation and the design-build-test cycle. A crucial part of this process is the convergence of modelling and experiment. The aim of this thesis is to improve the design principles employed by Synthetic Biology in the context of Gene Regulatory Networks (GRNs). Small Ribonucleic Acids (sRNAs), in particular, are focussed on as a mechanism for post-transcriptional
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11

Pinzon, Restrepo Natalia. "Characterization of regulatory noncoding RNAs : the U1 small nuclear RNA and Cajal body-specific box C/D guide RNAs." Toulouse 3, 2011. http://thesesups.ups-tlse.fr/2458/.

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Les cellules contiennent de nombreux ARNs non-codants qui jouent un rôle essentiel dans toutes les étapes de l'expression génique. Nos travaux concernent la caractérisation de possibles nouvelles fonctions associés à deux classes d'ARNs non-codants : l'ARN U1 et les scaARNs. Le petit ARN nucléaire U1 forme une ribonucléoparticule (snRNP U1) qui joue un rôle clé dans l'épissage des ARN pré-messagers. De plus, l'ARN U1 semble intervenir dans d'autres étapes de la synthèse des ARNm fonctionnels. Nos travaux ont démontré qu'une fraction de l'ARN U1 interagit spécifiquement avec la protéine TAF15,
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12

Weiss, Andy. "Non-classical regulators in Staphylococcus aureus." Scholar Commons, 2017. http://scholarcommons.usf.edu/etd/6779.

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Staphylococcus aureus is a highly problematic human pathogen due to its ability to cause devastating infections, paired with a capacity to withstand the action of a large fraction of available antibiotics. Both pathogenicity and antibiotic resistance are encoded by numerous genomic elements, though the expression of these factors is energetically costly and not always beneficial for cellular survival. Therefore, S. aureus has developed sophisticated regulatory networks to integrate a multitude of signals, enabling it to navigate the delicate balance between its pathogenic lifestyle and baselin
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13

Santana, Estevan Alexis. "Identification of a Fur-regulated small regulatory RNA in nontypeable Haemophilus influenzae." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1410472201.

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14

Taylor, Patrick. "The Role of Two-Component and Small RNA Regulatory Systems in Pseudomonas aeruginosa Biofilms." Thesis, Université d'Ottawa / University of Ottawa, 2019. http://hdl.handle.net/10393/39614.

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Biofilms are a crucial adaptation for bacterial survival against stresses from external environments. Biofilms are adherent colonies of sessile bacteria embedded within a self-produced matrix. Bacterial control over formation, maintenance, and response to external stresses are strictly regulated. However, complexities of intracellular signaling for biofilm regulation are still not fully understood. In this thesis, I report on two distinct regulatory systems important for biofilm formation in the opportunistic pathogen Pseudomonas aeruginosa. The first regulatory system I report on is the two-
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15

Seekircher, Stephanie [Verfasser], and Petra [Akademischer Betreuer] Dersch. "Identification of regulatory factors that control the synthesis of the small regulatory RNA CsrC in Yersinia pseudotuberculosis / Stephanie Seekircher ; Betreuer: Petra Dersch." Braunschweig : Technische Universität Braunschweig, 2014. http://d-nb.info/1175821209/34.

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16

Almasude, Eden. "Characterization of SraB, a novel small RNA molecule, in the pathogenic bacterium Shigella dysenteriae." Ohio University Honors Tutorial College / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=ouhonors1307114184.

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17

Gripenland, Jonas. "Regulatory roles of two small RNAs in the human pathogen Listeria monocytogenes and the evaluation of an alternative infection model." Doctoral thesis, Umeå universitet, Institutionen för molekylärbiologi (Medicinska fakulteten), 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-55432.

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Listeriosis is a potentially lethal disease caused by the Gram-positive facultative intracellular pathogen Listeria monocytogenes (L.m.). L.m. is found ubiquitously in the environment and infects humans via ingestion of contaminated food. Contaminated products are usually derived from ruminants and involve dairy products and different kinds of processed meat. Listeriosis is a potential lifethreatening disease with a total mortality rate of 20-30 %. The development of listeriosis may lead to meningitis and septicemia or other invasive diseases. Pregnant women are of increased risk of developing
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18

Chen, Jun. "Conifer Evolution, from Demography and Local Adaptation to Evolutionary Rates : Examples from the Picea genus." Doctoral thesis, Uppsala universitet, Växtekologi och evolution, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-177482.

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Evolutionary process can be inferred at three different levels: the species level, the population level and the molecular level. In this thesis, I applied approaches at these three levels and aimed to get a comprehensive picture of conifer evolution, from speciation and demography to geographic variation and local adaptation, and then to the molecular evolution of proteins and small regulatory RNAs. Spruce species have been observed to possess a large number of trans-species shared polymorphisms. Using an “Isolation with migration” model, we found that the large effective population size of sp
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19

Balasubramanian, Deepak. "Pseudomonas Aeruginosa AmpR Transcriptional Regulatory Network." FIU Digital Commons, 2013. http://digitalcommons.fiu.edu/etd/863.

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In Enterobacteriaceae, the transcriptional regulator AmpR, a member of the LysR family, regulates the expression of a chromosomal β-lactamase AmpC. The regulatory repertoire of AmpR is broader in Pseudomonas aeruginosa, an opportunistic pathogen responsible for numerous acute and chronic infections including cystic fibrosis. Previous studies showed that in addition to regulating ampC, P. aeruginosa AmpR regulates the sigma factor AlgT/U and production of some quorum sensing (QS)-regulated virulence factors. In order to better understand the ampR regulon, the transcriptional profiles generated
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20

Pernitzsch, Sandy Ramona [Verfasser], Cynthia Mira [Gutachter] Sharma, and Dagmar [Gutachter] Beier. "Functional Characterization of the abundant and conserved small regulatory RNA RepG in Helicobacter pylori / Sandy Ramona Pernitzsch ; Gutachter: Cynthia Mira Sharma, Dagmar Beier." Würzburg : Universität Würzburg, 2016. http://d-nb.info/1241045542/34.

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21

Steige, Kim A. "Cis-regulatory variation and divergence in Capsella." Doctoral thesis, Uppsala universitet, Evolutionsbiologi, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-268953.

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Cis-regulatory changes in e.g. promoters or enhancers that affect the expression of a linked focal gene have long been thought to be important for adaptation. In this thesis, I investigate the selective importance and genomic correlates of cis-regulatory variation and divergence in the genus Capsella, using massively parallel sequencing data. This genus provides an opportunity to investigate cis-regulatory changes in response to polyploidization and mating system shifts, as it harbors three diploid species, the outcrosser Capsella grandiflora and the selfers Capsella orientalis and Capsella ru
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22

Eyraud, Alex. "Étude fonctionnelle et structurale d’un ARN régulateur exprimé par les staphylocoques dorés : implication dans la résistance aux antibiotiques." Thesis, Rennes 1, 2014. http://www.theses.fr/2014REN1S130/document.

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Staphylococcus aureus est une bactérie pathogène de l'homme impliquée dans de nombreuses infections nosocomiales et communautaires. Comme elle acquiert régulièrement de nouvelles résistances à diverses classes d'antibiotiques, il devient urgent de proposer de nouvelles cibles thérapeutiques. Certains ARN régulateurs (ARNrég) sont importants dans le contrôle de la virulence et de la pathogénie de la bactérie. Au cours de ma thèse, nous avons étudié la fonction d'un ARNrég, appelé SprX (alias RsaOR), exprimé par Staphylococcus aureus. Dans un premier temps, nous avons montré que, dans les souche
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23

Jonsäll, Linnea. "Mutational analysis of the csgD mRNA leader: search for a mode of regulation." Thesis, Uppsala universitet, Institutionen för biologisk grundutbildning, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-208415.

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The CsgD protein is the master regulator of a pathway leading to the formation of curli, in essence regulating the switch between a motile and a sessile lifestyle for bacteria. The 5’-UTR region of the csgD mRNA is a hotspot for multiple regulatory small RNAs (sRNA) involved in a complex regulatory network. Even though it is previously known how the interaction takes place it is unknown how sRNA binding affects the translational activity. In order to suggest a mode of regulation a mutational assay was performed by making changes in the csgD 5’-UTR and investigate what the translational effects
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24

Lucas, Darren Edward. "Coordinated Regulation of Salmonella Virulence Genes by the BarA/SirA Two-Component System and the Csr Global Regulatory System." The Ohio State University, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=osu1374087620.

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25

D'Halluin, Alexandre. "Etude du transcriptome primaire codant et non-codant de Bordetella pertussis, caractérisation de l'impact des séquences d'insertion." Thesis, Lille 2, 2018. http://www.theses.fr/2018LIL2S008/document.

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Bordetella pertussis, l’agent responsable de la coqueluche, provoque près de 200000 morts par an dans le monde. Malgré une forte couverture vaccinale, une réémergence de la maladie a été observée dans les pays développés, liée en partie à une adaptation à la pression vaccinale. Les souches capables d’échapper à la réponse immunitaire montrent des réarrangements génomiques importants, provoqués par des éléments génétiques mobiles (IS) présents en plus de 230 copies, qui pourraient impacter sur la transcription des gènes et ARN régulateurs du pathogène.Pour élucider l’impact des IS sur le transc
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26

Reignier, Jérémy. "Etude de petits ARN régulateurs chez Helicobacter pylori." Thesis, Bordeaux 2, 2010. http://www.theses.fr/2010BOR21745/document.

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Ces dernières années de nombreuses recherches ont montré l’importance des petits ARN dans la régulation de l’expression des gènes, chez tous les organismes vivants, des bactéries aux mammifères. Le projet de cette thèse était de recherche et d’identifier des petits ARN chez une bactérie pathogène pour l’homme, Helicobacter pylori (Hp). Cette bactérie colonise exclusivement l’estomac humain, un organe qui pendant longtemps a été considéré comme étant stérile, en raison du pH parfois très acide qui y règne. L’infection persistante de l’estomac humain causée par Hp est associée avec plusieurs pat
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Wang, Mengxi. "Role of Map4k4 in Skeletal Muscle Differentiation: A Dissertation." eScholarship@UMMS, 2013. http://escholarship.umassmed.edu/gsbs_diss/675.

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Skeletal muscle is a complicated and heterogeneous striated muscle tissue that serves critical mechanical and metabolic functions in the organism. The process of generating skeletal muscle, myogenesis, is elaborately coordinated by members of the protein kinase family, which transmit diverse signals initiated by extracellular stimuli to myogenic transcriptional hierarchy in muscle cells. Mitogen-activated protein kinases (MAPKs) including p38 MAPK, c-Jun N terminal kinase (JNK) and extracellular signal-regulated protein kinase (ERK) are components of serine/threonine protein kinase cascades th
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Liu, Ming-lai, and 廖明麗. "Roles of microRNAs in hepatocellular carcinoma: biomarkers, matabolisms and pathway regulators." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B46918929.

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29

Stillitano, Alexia. "miR-34a : a key regulator of adipogenesis." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/206552.

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Introduction Globesity, the worldwide obesity epidemic, represents a major threat and public health burden. An uncontrolled expansion of the adipose tissue followed by a chronic low-grade inflammation leads to the dysfunction of the adipose organ resulting in obesity and its associated metabolic complications. Uncovering the mechanisms of adipogenesis, the development of adipocytes, therefore strikes as a key strategy in combating the disease. MicroRNAs (miRs), a class of small non-coding RNAs, have emerged in recent years as crucial modulators of diverse biological processes such as cell prol
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30

Mohorianu, Irina-Ioana. "Deciphering the regulatory mechanisms of small RNAs in plants." Thesis, University of East Anglia, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.577684.

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Small RN As (sRNAs) are 20-25 nucleotides long non-coding RN As that act as guides for the highly sequence-specific regulatory mechanism in eukary- otes known as RNA silencing. Plants are known to produce a highly complex and diverse population of regulatory sRNAs involved in different processes, such as transcriptional and post-transcriptional regulation of gene expres- sion levels, genome maintenance and defense against pathogens. Until now the computational methods have mainly focused on the identifica- tion and description of a special class of sRNAs, called miRNAs. However, it has been sh
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31

Hall, Holly. "The sporulation-specific small regulatory RNAs of Bacillus subtilis." Thesis, University of Warwick, 2017. http://wrap.warwick.ac.uk/102346/.

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Constantly changing environments in nature have led to bacteria evolving regulatory strategies that result in differential gene expression. A novel and understudied aspect of these networks are regulatory RNAs. The Gram-positive model organism Bacillus subtilis not only modulates gene expression to survive a variety of stresses, but also can form endospores to ensure its survival. Sporulation is an essential survival mechanism for many species, allowing them to enter a state of dormancy with resistance to various harsh conditions. This, in turn, ensures survival of not only the population, but
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32

Kim, Jin-Kuk. "Small regulatory RNAs in mammals : genomics, function and evolution." Thesis, Massachusetts Institute of Technology, 2011. http://hdl.handle.net/1721.1/65516.

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Thesis (Ph. D.)--Harvard-MIT Division of Health Sciences and Technology, 2011.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references.<br>This thesis explores two aspects of small regulatory RNAs in mammals: (1) the genomic origin of mammalian piwi-interacting RNAs (piRNAs), (2) the evolutionary and functional implication of the seed-based target recognition mechanism of microRNAs (miRNAs). First, we participated in the discovery of mammalian piRNAs from adult rat testes. Our initial characterization of mammalian piRNAs by high-throughput sequencing revealed the peculi
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McCully, Mark Alan. "The delivery of small regulatory RNAs by gold nanoparticles." Thesis, University of Glasgow, 2015. http://theses.gla.ac.uk/6478/.

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The traditional paradigm relying on drug discovery to treat and heal the body is changing. Medicine for the 21st century is moving towards using the body’s internal language of DNA and RNA to cure disease and repair injuries to the body. We now appreciate the complexity of signalling through the genome and its transcribed RNA. The role of micro RNAs and short interfering RNAs are gaining much interest as potential therapeutics. This interest has been sparked by the discovery that the dysregulation of micro RNAs is the origin for a spectrum of diseases from cancer through to osteoporosis. Small
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34

Harding, J. "Small RNAs as regulators of early vertebrate development." Thesis, University College London (University of London), 2011. http://discovery.ucl.ac.uk/1335827/.

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This thesis explores the role of small RNAs as regulators of early vertebrate development using the frog species Xenopus laevis and Xenopus tropicalis as experimental systems. Firstly, I investigate spatial control of Nodal signalling, which is critical for organisation of the vertebrate body plan during gastrulation, by uncovering the functional relevance and mechanism of spatial regulation of the Nodal coreceptor Cripto-1 in the early X. laevis embryo. Xenopus Cripto-1 (XCR1) mRNA is ubiquitous in the early embryo, but the protein is absent in the prospective endoderm, from which Nodal signa
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Axmann, Ilka Maria. "The regulatory potential of marine cyanobacteria transcriptional factors and small RNAs /." [S.l.] : [s.n.], 2006. http://deposit.ddb.de/cgi-bin/dokserv?idn=983792801.

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36

Joshi, Nimitray. "Unraveling the role of small regulatory RNAs (sRNAs) in Clostridium difficile." Thesis, University of Nottingham, 2016. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.716674.

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Clostridium difficile is an opportunistic human pathogen capable of causing a spectrum of diseases ranging from relatively mild antibiotic-associated diarrhoea to severe and life-threatening conditions such as pseudomembranous colitis. Despite its medical importance, comparatively little is known about the regulatory processes that take place in response to environmental changes or to maintain and co-ordinate housekeeping functions. Over the last couple of years, it has become apparent that small RNAs (sRNAs) are playing important regulatory roles in bacteria. Utilizing RNA sequencing (RNA-Seq
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Lam, Siu-chi, and 林少志. "Identification of microRNA 885-5p as a novel regulator of tumor metastasis in colorectal cancer." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/197135.

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MicroRNAs (miRNAs) are a small non-coding RNAs that play a crucial role in cellular proliferation, differentiation and apoptosis by regulating gene expression via post-translation repression or degradation. They are involved in the regulation of various human diseases including colorectal cancer (CRC). CRC is the third most common cancer in the world and second leading cause of cancer death in Hong Kong and United States. Distant metastasis is the main cause of high mortality rate. In most CRC patients, liver is the most common site of distant metastasis, which is often associated with treatme
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Rajagopalan, Ramya. "Genomics and regulatory functions of microRNAs and small silencing RNAs in Arabidopsis thaliana." Thesis, Massachusetts Institute of Technology, 2007. http://hdl.handle.net/1721.1/43787.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 2007.<br>After leaf 151, two journal articles with separate numberings (leaves [69]-79, 565-577).<br>Includes bibliographical references.<br>Small RNA-mediated gene silencing is a mechanism widely employed by eukaryotes to repress many loci including some involved in critical developmental transitions. In plants, endogenous small RNAs consist of two broad classes, the ~21-nucleotide (nt) microRNAs (miRNAs) and the diverse ~22-24-nt trans-acting and heterochromatic short interfering RNAs (siRNAs). In order to more extensi
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Okaro, Udoka. "A Small RNA and DNA Binding Protein Contribute to Biofilm Development in Bartonella henselae." Scholar Commons, 2019. https://scholarcommons.usf.edu/etd/7878.

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A biofilm, which is associated with 80% of chronic infections in humans, is formed when bacteria aggregate, attach to a substrate and secrete a matrix protecting the bacteria from host cell defenses and antibiotics. Bartonella henselae (B. henselae) is the causative agent of cat scratch disease, persistent bacteremia, and one of the most frequently reported causes of blood-culture negative endocarditis (BCNE) in patients. The ability of B. henselae to adhere to the heart valve, form a biofilm and vegetation to cause endocarditis increases the morbidity and mortality rate in infected patients.
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Sheehan, Lauren Marie. "Characterizing the AbcR/VtlR system in the Rhizobiales." Diss., Virginia Tech, 2018. http://hdl.handle.net/10919/96536.

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Rhizobiales encompass a diverse group of microbes, ranging from free-living, soil-dwelling bacteria to disease-causing, intracellular pathogens. Although the lifestyle of these organisms vary, many genetic systems are well conserved. One system, named the AbcR/VtlR system, is found throughout rhizobiales, and even extends to bacteria in other orders within the Alphaproteobacteria. The AbcR sRNAs are an example of sibling sRNAs, where two copies of the abcR gene are typically present in the genome. The AbcRs are involved in the negative regulation of ABC-type transport systems, which are impo
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Herzog, Roman [Verfasser], and Kai [Akademischer Betreuer] Papenfort. "Small regulatory RNAs controlling complex phenotypes in Vibrio cholerae / Roman Herzog ; Betreuer: Kai Papenfort." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2020. http://d-nb.info/122609256X/34.

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Wilf, Nabil M. "The role of post-transcriptional regulators in pathogenesis and secondary metabolite production in Serratia sp. ATCC 39006." Thesis, University of Cambridge, 2011. https://www.repository.cam.ac.uk/handle/1810/245284.

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Serratia sp. ATCC 39006 (S39006) is a Gram-negative bacterium that is virulent in plant (potato) and animal (Caenorhabditis elegans) models. It produces two secondary metabolite antibiotics, prodigiosin and a carbapenem, and the plant cell wall degrading exoenzymes, pectate lyase and cellulase. A complex regulatory network controls production of prodigiosin, including a quorum sensing (QS) system, and the role of post-transcriptional regulation was investigated. It was hypothesized that Hfq-dependent small regulatory RNAs (sRNAs) might also play a role. Hfq is an RNA chaperone involved in post
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Waldmann, Barbara Ellen [Verfasser], and Petra [Akademischer Betreuer] Dersch. "Identification and expression analysis of small regulatory RNAs in Yersinia pseudotuberculosis / Barbara Ellen Waldmann ; Betreuer: Petra Dersch." Braunschweig : Technische Universität Braunschweig, 2014. http://d-nb.info/1175821578/34.

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44

Müller, Katrin Monika Hedwig [Verfasser]. "Small regulatory RNAs promoting the oxidative stress response and adaptive metabolic changes in Rhodobacter sphaeroides / Katrin Monika Hedwig Müller." Gießen : Universitätsbibliothek, 2017. http://d-nb.info/1131039645/34.

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Müller, Katrin [Verfasser]. "Small regulatory RNAs promoting the oxidative stress response and adaptive metabolic changes in Rhodobacter sphaeroides / Katrin Monika Hedwig Müller." Gießen : Universitätsbibliothek, 2017. http://d-nb.info/1131039645/34.

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46

Dam, Sushovan. "Post-transcriptional regulation of porin expression in Escherichia coli and its impact on antibiotic resistance." Thesis, Aix-Marseille, 2018. http://www.theses.fr/2018AIXM0641/document.

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Chez les bactéries à Gram-négatif, l’imperméabilité de la membrane externe est un facteur majeur contribuant au développement de la résistance. Chez Escherichia coli, les porines OmpF et OmpC sont des protéines de la membrane externe qui forment des canaux pour la diffusion de petites molécules hydrophiles tels que les antibiotiques. L’expression des porines est soumise à une régulation fine, et des petits ARN non-codants (sRNAs, small RNAs) jouent un rôle important au niveau post-transcriptionnel. Dans ce cadre, et en utilisant E. coli comme bactérie modèle, les objectifs de mon travail de th
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47

Jiang, Yi Hsin, and 江弈芯. "Identification of a regulatory small RNA encoded from." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/64880570605508017846.

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48

Rajasethupathy, Priyamvada. "Novel Small-RNA Mediated Gene Regulatory Mechanisms for Long-Term Memory." Thesis, 2012. https://doi.org/10.7916/D83N29CX.

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Memory storage and memory-related synaptic plasticity rely on precise spatiotemporal regulation of gene expression. To explore the role of small RNAs in memory-related synaptic plasticity we carried out massive parallel sequencing to profile the small RNAs of Aplysia. We identified 170 distinct 21-23 nt sized miRNAs, 13 of which were novel and specific to Aplysia. Nine miRNAs were brain-enriched, and several of these were rapidly down-regulated by transient exposure to serotonin, a modulatory neurotransmitter released during learning. Two abundant, and conserved brain-specific miRNAs, miR-124
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49

"Database construction and computational analysis of bacterial small regulatory RNAs." 2013. http://library.cuhk.edu.hk/record=b5884382.

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Li, Lei.<br>Thesis (Ph.D.)--Chinese University of Hong Kong, 2013.<br>Includes bibliographical references (leaves 85-91).<br>Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web.<br>Abstracts also in Chinese.
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50

Pernitzsch, Sandy Ramona. "Functional Characterization of the abundant and conserved small regulatory RNA RepG in Helicobacter pylori." Doctoral thesis, 2015. https://doi.org/10.25972/OPUS-12268.

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Bacterial small non-coding RNAs (sRNAs) play fundamental roles in controlling and finetuning gene expression in a wide variety of cellular processes, including stress responses, environmental signaling and virulence in pathogens. Despite the identification of hundreds of sRNA candidates in diverse bacteria by genomics approaches, the mechanisms and regulatory capabilities of these posttranscriptional regulators have most intensively been studied in Gram-negative Gammaproteobacteria such as Escherichia coli and Salmonella. So far, almost nothing is known about sRNA-mediated regulation (riboregu
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