Academic literature on the topic 'Regulatory T cells subsets'

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Journal articles on the topic "Regulatory T cells subsets"

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Kupriyanov, S. V., A. I. Sinitsky, and I. I. Dolgushin. "Multiple subsets of regulatory T-cells." Bulletin of Siberian Medicine 19, no. 3 (2020): 144–55. http://dx.doi.org/10.20538/1682-0363-2020-3-144-155.

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Mohammadnia-Afrouzi, Mousa, Mehdi Shahbazi, Sedigheh Baleghi Damavandi, Ghasem Faghanzadeh Ganji, and Soheil Ebrahimpour. "Regulatory T-cell: Regulator of Host Defense in Infection." Journal of Molecular Biology Research 7, no. 1 (2017): 9. http://dx.doi.org/10.5539/jmbr.v7n1p9.

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Based on diverse activities and production of several cytokines, T lymphocytes and T helper cells are divided into Th1, Th2, Th17 and regulatory T-cell (T regs) subsets based on diverse activities and production of several cytokines. Infectious agents can escape from host by modulation of immune responses as effector T-cells and Tregs. Thus, regulatory T-cells play a critical role in suppression of immune responses to infectious agents such as viruses, bacteria, parasites and fungi and as well as preserving immune homeostasis. However, regulatory T-cell responses can advantageous for the body
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J. Kosten, Ilona, and Thomas Rustemeyer. "Generation, Subsets and Functions of Inducible Regulatory T Cells." Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry 13, no. 3 (2015): 139–53. http://dx.doi.org/10.2174/1871523013666141126100019.

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Sayed, D., A. Eltayeb, N. Afifi, and M. Ibrahim. "485 Regulatory T Cells Subsets in Children with Sle." Archives of Disease in Childhood 97, Suppl 2 (2012): A142. http://dx.doi.org/10.1136/archdischild-2012-302724.0485.

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Locksley, Richard M. "Nine lives: plasticity among T helper cell subsets." Journal of Experimental Medicine 206, no. 8 (2009): 1643–46. http://dx.doi.org/10.1084/jem.20091442.

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The division of labor among two types of T helper (Th) subsets, first described over 20 yr ago, has been buffeted by the discovery of new subsets and new cytokines that can be coaxed out of T cells with increasing disregard for the subset of origin. Although Th17 cells and regulatory T (T reg) cells are widely accepted subsets, and others are being proposed, their plasticity is difficult to reconcile with the definitions of Th subsets as put forth in the initial description of Th1 and Th2 cells. A deeper molecular context will be required to reconcile the ever-increasing complexity of effector
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Yin, Xiangyun, Shuting Chen, and Stephanie C. Eisenbarth. "Dendritic Cell Regulation of T Helper Cells." Annual Review of Immunology 39, no. 1 (2021): 759–90. http://dx.doi.org/10.1146/annurev-immunol-101819-025146.

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As the professional antigen-presenting cells of the immune system, dendritic cells (DCs) sense the microenvironment and shape the ensuing adaptive immune response. DCs can induce both immune activation and immune tolerance according to the peripheral cues. Recent work has established that DCs comprise several phenotypically and functionally heterogeneous subsets that differentially regulate T lymphocyte differentiation. This review summarizes both mouse and human DC subset phenotypes, development, diversification, and function. We focus on advances in our understanding of how different DC subs
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Xia, Xin, Jun Yang, and Shengjun Wang. "Follicular Regulatory T Cells in Systemic Lupus Erythematosus." Journal of Immunology Research 2021 (July 13, 2021): 1–9. http://dx.doi.org/10.1155/2021/9943743.

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Follicular regulatory T (Tfr) cells are the regulatory T cell subset mainly localized in the germinal center (GC), acting as modulators of GC responses. They can disrupt Tfh cell- and B cell-linked recognition, induce Tfh apoptosis, and suppress B cell function. Evidences show that dysregulated Tfr cells are associated with the disease activity index and serum autoantibody levels, influencing the development of systemic lupus erythematosus (SLE). This review focuses on the interaction among Tfr, Tfh, and B cells, summarizes the characterization and function of Tfr cells, concludes the imbalanc
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Hoechst, Bastian, Jaba Gamrekelashvili, Michael P. Manns, Tim F. Greten, and Firouzeh Korangy. "Plasticity of human Th17 cells and iTregs is orchestrated by different subsets of myeloid cells." Blood 117, no. 24 (2011): 6532–41. http://dx.doi.org/10.1182/blood-2010-11-317321.

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Abstract CD4+ T helper cell differentiation is essential for mounting robust immune responses without compromising unresponsiveness toward self-tissue. Here, we show that different subsets of myeloid cells isolated from human peripheral blood modulate TGF-β–dependent CD4+ T-cell developmental programs ex vivo. Human CD14+HLA-DR−/low myeloid-derived suppressor cells (MDSCs) induce Foxp3+ regulatory T cells, whereas CD14+HLA-DR+ monocytes promote generation of IL-17–secreting RORc+ Th17 cells when cocultured with naive CD4+ T cells. More importantly, not only do these 2 subsets modulate the de n
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Yadav, Mahesh, Cedric Louvet, Dan Davini, et al. "Neuropilin-1 distinguishes natural and inducible regulatory T cells among regulatory T cell subsets in vivo." Journal of Experimental Medicine 209, no. 10 (2012): 1713–22. http://dx.doi.org/10.1084/jem.20120822.

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Foxp3+ CD4+ T helper cells called regulatory T (T reg) cells play a key role in controlling reactivity to self-antigens and onset of autoimmunity. T reg cells either arise in thymus and are called natural T reg (nT reg) cells or are generated in the periphery through induction of Foxp3 and are called inducible T reg (iT reg) cells. The relative contributions of iT reg cells and nT reg cells in peripheral tolerance remain unclear as a result of an inability to separate these two subsets of T reg cells. Using a combination of novel TCR transgenic mice with a defined self-antigen specificity and
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Hall, Bruce M., Nirupama D. Verma, Giang T. Tran, and Suzanne J. Hodgkinson. "Distinct regulatory CD4+T cell subsets; differences between naïve and antigen specific T regulatory cells." Current Opinion in Immunology 23, no. 5 (2011): 641–47. http://dx.doi.org/10.1016/j.coi.2011.07.012.

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Dissertations / Theses on the topic "Regulatory T cells subsets"

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Lei, Hong. "Human natural regulatory T cells subsets." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2014. http://dx.doi.org/10.18452/16958.

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Regulatorische T-Zellen (Treg) eröffnen neue immuntherapeutische Wege zur Kontrolle unerwünschter Immunreaktionen, jedoch wirft die Heterogenität dieser Zellen die Frage auf, welche Treg-Population für die klinische Anwendung. Darauf basierend werden in dieser Arbeit drei Fragestellungen bearbeitet: i) Bestimmung der Häufigkeit von Tregs und deren Subpopulationen in verschiedenen Altersgruppen bei Empfängern einer Organtransplantation (Tx) und einer gesunden Kontrollgruppe; ii) Vergleich der Suppressorkapazität verschiedener Treg-Populationen und in vitro-Expansion der Zellen unter Erhaltung i
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Putheti, Prabhakar. "CD4+CD25+ T regulatory cells in multiple sclerosis /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7349-962-5.

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Cao, Duojia. "CD25+CD4+ regulatory T cells in rheumatic disease /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-178-4/.

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Maynard, Craig Lueland. "IL-10-competent regulatory T cells development, phenotype and function /." Thesis, Birmingham, Ala. : University of Alabama at Birmingham, 2007. https://www.mhsl.uab.edu/dt/2009r/maynard.pdf.

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Hirani, S. "The characterisation of human umbilical cord blood regulatory T cell subsets." Thesis, University College London (University of London), 2012. http://discovery.ucl.ac.uk/1344048/.

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Umbilical cord blood (CB) is recognised to be a valuable alternative to bone marrow (BM) as a source of hematopoietic stem cells (HSC). The occurrence of Graft vs. Host Disease (GvHD) after CB transplantation has been reported to be less severe in comparison to BM transplants. In addition to the naive state of immune cells, the action of immuno-suppressive cells such as regulatory T cells (Treg) may contribute to the positive aspects observed in CB transplants. This study investigated the phenotypic and functional characteristics of CB Treg and their potential for expansion in culture. In addi
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Booth, Nicola Jane. "The characterisation of human regulatory T cell subsets in ageing and atopy." Thesis, University College London (University of London), 2010. http://discovery.ucl.ac.uk/20160/.

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The immune system must be controlled to prevent damage caused by inappropriate responses and extended inflammation. Regulatory T cells (Tregs), known to be generated by the thymus, must be maintained in the face of an ever-increasing human lifespan and associated thymic atrophy in order to protect the host, but whether they are maintained by expansion of pre-existing Tregs or conversion of conventional T cells is not yet known. There are known to be two subsets of FOXP3+ regulatory T cells: naive and memory cells, expressing CD45RA and CD45RO respectively. In this work the characteristics of C
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Lei, Hong [Verfasser], Hans-Dieter [Akademischer Betreuer] Volk, Richard [Akademischer Betreuer] Lucius, and Petra [Akademischer Betreuer] Reinke. "Human natural regulatory T cells subsets : functional characterization and T cell receptor repertoire analysis / Hong Lei. Gutachter: Hans-Dieter Volk ; Richard Lucius ; Petra Reinke." Berlin : Humboldt Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2014. http://d-nb.info/1051677475/34.

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Kalra, Seema. "Characterisation of pathogenic T helper and T regulatory cell subsets in relapse and progression in multiple sclerosis." Thesis, Keele University, 2017. http://eprints.keele.ac.uk/4215/.

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Multiple Sclerosis (MS) is one of the commonest disabling neurological diseases affecting the young in the developed world. It affects the central nervous system (CNS) and is characterised by inflammation with neuronal demyelination /degeneration and failure of remyeli nation/regeneration. Inflammation is present throughout the course of the disease though it differs qualitatively and/or quantitatively in different phases. T cells are the central players in the immune processes and more so in an autoimmune disease like MS. Autopsy studies continue to add to our understanding of CNS inflammatio
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Barra, Melanie Marianne [Verfasser], and Markus [Akademischer Betreuer] Feuerer. "Transcription factor 7 limits regulatory T cell generation and influences peripheral T cell subsets / Melanie Marianne Barra ; Betreuer: Markus Feuerer." Heidelberg : Universitätsbibliothek Heidelberg, 2014. http://d-nb.info/1180735056/34.

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Wendering, Désirée Jacqueline [Verfasser]. "Regulatory T cells in adoptive immunotherapy: from subset characterization to functional testing / Désirée Jacqueline Wendering." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2021. http://d-nb.info/1228860807/34.

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Books on the topic "Regulatory T cells subsets"

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Kassiotis, George, and Adrian Liston, eds. Regulatory T Cells. Humana Press, 2011. http://dx.doi.org/10.1007/978-1-61737-979-6.

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Taams, Leonie S., Marca H. M. Wauben, and Arne N. Akbar, eds. Regulatory T Cells in Inflammation. Birkhäuser Basel, 2005. http://dx.doi.org/10.1007/b137037.

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Jiang, Shuiping, ed. Regulatory T Cells and Clinical Application. Springer US, 2008. http://dx.doi.org/10.1007/978-0-387-77909-6.

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Regulatory T cells: Methods and protocols. Humana Press, 2011.

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Wierenga, Edsko Albert. Functional subsets of T helper cells: Implications for allergic disease. University of Amsterdam, 1992.

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Zheng, Song-Guo, ed. T Regulatory Cells in Human Health and Diseases. Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-15-6407-9.

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Compans, R. W., M. D. Cooper, T. Honjo, et al., eds. CD4+CD25+ Regulatory T Cells: Origin, Function and Therapeutic Potential. Springer Berlin Heidelberg, 2005. http://dx.doi.org/10.1007/3-540-27702-1.

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Na, Songqing, and Chandrasekar Venkataraman Iyer. Effector CD4+ T cells in health and disease 2007. Transworld Research Network, 2007.

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Eljaafari, Assia, and Pierre Miossec. Cellular side of acquired immunity (T cells). Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0049.

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The adaptive T-cell response represents the most sophisticated component of the immune response. Foreign invaders are recognized first by cells of the innate immune system. This leads to a rapid and non-specific inflammatory response, followed by induction of the adaptive and specific immune response. Different adaptive responses can be promoted, depending on the predominant effector cells that are involved, which themselves depend on the microbial/antigen stimuli. As examples, Th1 cells contribute to cell-mediated immunity against intracellular pathogens, Th2 cells protect against parasites,
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Regulatory T cells. Munksgaard, 2001.

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Book chapters on the topic "Regulatory T cells subsets"

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Fowler, Daniel, Petra Hoffmann, and Matthias Edinger. "Functionally Defined T Cell Subsets in Transplantation Biology and Therapy: Regulatory T Cells and Th2 Cells." In Cancer Treatment and Research. Springer US, 2008. http://dx.doi.org/10.1007/978-0-387-78580-6_7.

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Espinosa, Jaclyn R., Joshua D. Wheaton, and Maria Ciofani. "In Vitro Differentiation of CD4+ T Cell Effector and Regulatory Subsets." In Methods in Molecular Biology. Springer US, 2020. http://dx.doi.org/10.1007/978-1-0716-0266-9_7.

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Wang, Rong-Fu, and Jinping Zhang. "Regulatory T Cells." In Encyclopedia of Cancer. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-16483-5_5014.

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Florou, Vaia, and Breelyn A. Wilky. "Regulatory T cells." In Immunotherapy of Sarcoma. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-93530-0_3.

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Berod, Luciana, Katharina Lahl, Matthias Lochner, Christian T. Mayer, and Tim Sparwasser. "Regulatory T Cells." In Inflammation - From Molecular and Cellular Mechanisms to the Clinic. Wiley-VCH Verlag GmbH & Co. KGaA, 2017. http://dx.doi.org/10.1002/9783527692156.ch55.

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Peiser, Matthias. "Regulatory T Cells." In Encyclopedia of Immunotoxicology. Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-27786-3_1586-1.

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Peiser, Matthias. "Regulatory T Cells." In Encyclopedia of Immunotoxicology. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-54596-2_1586.

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Onishi, Hideya, Takashi Morisaki, and Mitsuo Katano. "Regulatory T Cells." In Immunotherapy of Cancer. Springer Japan, 2016. http://dx.doi.org/10.1007/978-4-431-55031-0_21.

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Corrigan, Chris, and Kimuli Ryanna. "Regulatory T Cells." In Inflammation and Allergy Drug Design. Wiley-Blackwell, 2011. http://dx.doi.org/10.1002/9781444346688.ch4.

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Wang, Rong-Fu, and Jinping Zhang. "Regulatory T Cells." In Encyclopedia of Cancer. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-27841-9_5014-2.

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Conference papers on the topic "Regulatory T cells subsets"

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Velez, T. E., Y. M. Yoon, K. Blaine, et al. "Regulatory T Cell Subsets in Pulmonary Fibrosis." In American Thoracic Society 2021 International Conference, May 14-19, 2021 - San Diego, CA. American Thoracic Society, 2021. http://dx.doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1305.

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Griffith, J., L. Faustino, and A. Luster. "Regulatory T Cell Subsets Differentially Regulate the Immune Response to Influenza." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5829.

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Weiss, Vivian L., Timothy H. Lee, Todd D. Armstrong, and Elizabeth M. Jaffee. "Abstract 1923: Regulatory T-cell subsets suppress high avidity CD8 T-cell activation and trafficking." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-1923.

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Gara, Sudheer Kumar, Yanli Pang, Christine Hollander, and Li Yang. "Abstract 4988: FOXP3, a critical mediator of regulatory T-cell function, is expressed in subsets of myeloid cells." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-4988.

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Tsau, Jennifer, Michael Abadier, Brittney Atzmiller, et al. "Abstract 4043: Application of high complexity flow cytometry for Monitoring activated T-cells, T and B regulatory subsets in combination immunotherapy trials, melanoma case study." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-4043.

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Tsau, Jennifer, Michael Abadier, Brittney Atzmiller, et al. "Abstract 4043: Application of high complexity flow cytometry for Monitoring activated T-cells, T and B regulatory subsets in combination immunotherapy trials, melanoma case study." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-4043.

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Krause, Anja, Zhibo B. Xu, Wendy Wu, Ju Joh, and Stefan Worgall. "Imbalance Of Dendritic Cell Subsets And Regulatory T Cells In Enhanced RSV Pulmonary Disease Can Be Prevented By Immunization With Capsid-modified Ad Vector Expressing The RSV F Protein." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a4156.

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Segal, Leopoldo, Rohan Kulkarni, Anna Nolan, Michael D. Weiden, Doris B. Tse, and William N. Rom. "Regulatory T Cells And Th17 Cells In Bronchoalveolar Lavage." In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a1391.

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Roos-Engstrand, Ester, Anders Bucht, Anders Blomberg, Annelie Behndig, and Jamshid Pourazar. "Identification Of Regulatory T Cells In Stable COPD." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a3880.

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Moodley, Yuben, and Dion Tan. "Impaired Function Of T-Regulatory Cells In COPD." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a4544.

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Reports on the topic "Regulatory T cells subsets"

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Wong, Jr, and K. K. Regulatory T Cells and Host Anti-CML Responses. Defense Technical Information Center, 2008. http://dx.doi.org/10.21236/ada487614.

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Wong, Jr, and K. K. Regulatory T Cells and Host Anti-CML Responses. Defense Technical Information Center, 2009. http://dx.doi.org/10.21236/ada510759.

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Lorenz, Ulrike. Role of the Tyrosine Phosphatase SHP-1 and Regulatory T Cells in Breast Cancer. Defense Technical Information Center, 2008. http://dx.doi.org/10.21236/ada501068.

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Lorenz, Ulrike. Role of the Tyrosine Phosphatase SHP-1 and Regulatory T Cells in Breast Cancer. Defense Technical Information Center, 2007. http://dx.doi.org/10.21236/ada510570.

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Susurkova, Rumyana, Andrey Velichkov, Antoaneta Mihova, et al. Phosphorilated STAT5 Is Associated with Differential Activation Capacity of T Regulatory Cells in Women with Re productive Failure. "Prof. Marin Drinov" Publishing House of Bulgarian Academy of Sciences, 2021. http://dx.doi.org/10.7546/crabs.2021.03.15.

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