Relevant bibliographies by topics / Relaxivita

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  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers
  5. Reports

Academic literature on the topic 'Relaxivita'

Author: Grafiati
Published: 4 June 2021
Last updated: 18 February 2022

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Journal articles on the topic "Relaxivita"

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Sosnovsky, George, Shu Wen Li, N. Uma Maheswara Rao, and Robert C. Brasch. "Spin Labeled Chelating Agents and their Gadolinium Complexes as Contrast Enhancing Agents for NMR Imaging." Zeitschrift für Naturforschung B 40, no. 11 (1985): 1558–62. http://dx.doi.org/10.1515/znb-1985-1124.

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Spin labeled EDTA, CDTA and DTPA chelating agents and their gadolinium complexes were synthesized and evaluated for their effects on the spin-lattice (T1) and spin-spin (T2) relaxation times of water, plasma, and blood. It was found that the spin labeled chelating agents are effective proton relaxation agents. Although, the gadolinium complexes of these agents have superior relaxation properties, the differences in relaxivitv between the spin labeled complexes and the non-spin labeled gadolinium complexes are marginal. The spin labeled agents and their gadolinium complexes are expected to be v
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Jao, Jo-Chi, Po-Chou Chen, Yun-Ni Ting, Chia-Chi Hsiao, and Huay-Ben Pan. "THE IMPACT OF FACTOR TE ON THE MEASUREMENT OF T1 RELAXIVITY." Biomedical Engineering: Applications, Basis and Communications 20, no. 05 (2008): 277–85. http://dx.doi.org/10.4015/s1016237208000891.

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Relaxivity is a very important indicator to evaluate the signal enhancement caused by MRI contrast agents. Many factors can affect the relaxivity values. The aim of this study is to investigate the influence of factor TE in the curve-fitting equation for T1 measurements. A spin echo pulse sequence was used as the scanning method. The relaxivity of Gd -DTPA doped saline at a 1.5 T MR scanner was under investigation. Gd -DTPA is the most widely used MRI contrast agent nowadays. In this study, both computer simulations and phantom studies were performed. T1 values were calculated by using both sp
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Xiao, Yan-meng, Gui-yan Zhao, Xin-xiu Fang, et al. "A smart copper(ii)-responsive binuclear gadolinium(iii) complex-based magnetic resonance imaging contrast agent." RSC Adv. 4, no. 65 (2014): 34421–27. http://dx.doi.org/10.1039/c4ra04526b.

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The relaxivity of the complex was modulated by Cu<sup>2+</sup>, that is, in the absence of Cu<sup>2+</sup> the complex exhibited a relatively low relaxivity value of 6.40 mM<sup>−1</sup> s<sup>−1</sup>, while the addition of Cu<sup>2+</sup> triggered the relaxivity to 11.28 mM<sup>−1</sup> s<sup>−1</sup>, an enhancement of approximately 76%.
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Sigg, Severin J., Francesco Santini, Adrian Najer, Pascal U. Richard, Wolfgang P. Meier, and Cornelia G. Palivan. "Nanoparticle-based highly sensitive MRI contrast agents with enhanced relaxivity in reductive milieu." Chemical Communications 52, no. 64 (2016): 9937–40. http://dx.doi.org/10.1039/c6cc03396b.

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Antal, Iryna, Oliver Strbak, Iryna Khmara, et al. "MRI Relaxivity Changes of the Magnetic Nanoparticles Induced by Different Amino Acid Coatings." Nanomaterials 10, no. 2 (2020): 394. http://dx.doi.org/10.3390/nano10020394.

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In this study, we analysed the physico-chemical properties of positively charged magnetic fluids consisting of magnetic nanoparticles (MNPs) functionalised by different amino acids (AAs): glycine (Gly), lysine (Lys) and tryptophan (Trp), and the influence of AA–MNP complexes on the MRI relaxivity. We found that the AA coating affects the size of dispersed particles and isoelectric point, as well as the zeta potential of AA–MNPs differently, depending on the AA selected. Moreover, we showed that a change in hydrodynamic diameter results in a change to the relaxivity of AA–MNP complexes. On the
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Reeßing, Friederike, Sèvrin E. M. Huijsse, Rudi A. J. O. Dierckx, Ben L. Feringa, Ronald J. H. Borra, and Wiktor Szymański. "A Photocleavable Contrast Agent for Light-Responsive MRI." Pharmaceuticals 13, no. 10 (2020): 296. http://dx.doi.org/10.3390/ph13100296.

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Thanks to its innocuousness and high spatiotemporal resolution, light is used in several established and emerging applications in biomedicine. Among them is the modulation of magnetic resonance imaging (MRI) contrast agents’ relaxivity with the aim to increase the sensitivity, selectivity and amount of functional information obtained from this outstanding whole-body medical imaging technique. This approach requires the development of molecular contrast agents that show high relaxivity and strongly pronounced photo-responsiveness. To this end, we report here the design and synthesis of a light-
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Bryar, Traci R., and Rosemary J. Knight. "Laboratory studies of the effect of sorbed oil on proton nuclear magnetic resonance." GEOPHYSICS 68, no. 3 (2003): 942–48. http://dx.doi.org/10.1190/1.1581046.

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Proton NMR (nuclear magnetic resonance) measurements were made of T1 and T2 relaxation times of water in saturated sands containing varying amounts of sorbed oil on the grain surfaces. The porosity, surface area, and grain density of the sands and the relaxation times of the extracted pore water were also determined experimentally. Sorption of oil changed the relaxation time of water in the saturated sands through changes in surface area and surface relaxivity, the parameter used to quantify the ability of the surface of the pore space to reduce NMR relaxation times. In some cases the addition
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Zhu, Chunxiao, Hugh Daigle, and Steven L. Bryant. "Paramagnetic nanoparticles as nuclear magnetic resonance contrast agents in sandstone: Importance of nanofluid-rock interactions." Interpretation 4, no. 2 (2016): SF55—SF65. http://dx.doi.org/10.1190/int-2015-0137.1.

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Nuclear magnetic resonance has been applied in well logging to investigate pore size distribution with high resolution and accuracy based on the relaxation time distribution. However, due to the heterogeneity of natural rock, pore surface relaxivity, which links relaxation time and pore size, varies within the pore system. To analyze and alter pore surface relaxivity, we saturated Boise sandstone cores with positively charged zirconia nanoparticle dispersions in which nanoparticles can be adsorbed onto the sandstone pore wall, while negatively charged zirconia nanoparticles dispersions were us
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Fransen, Peter, Daniel Pulido, Lorena Simón-Gracia, et al. "r1andr2Relaxivities of Dendrons Based on a OEG-DTPA Architecture: Effect of Gd3+Placement and Dendron Functionalization." Journal of Nanotechnology 2015 (2015): 1–8. http://dx.doi.org/10.1155/2015/848020.

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In magnetic resonance imaging, contrast agents are employed to enhance the signal intensity. However, current commercial contrast agents are hindered by a low relaxivity constant. Dendrimers can be employed to create higher molecular weight contrast agents which have an increased relaxivity due to a lower molecular rotation. In this study, dendrimers containing DTPA derivatives as cores and/or branching units were used to chelate gadolinium ions. Locating the gadolinium ions inside the dendrimers results in higher relaxivity constants, possibly because the paramagnetic center is closer to the
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Goswami, Lalit N., Quanyu Cai, Lixin Ma, Satish S. Jalisatgi, and M. Frederick Hawthorne. "Synthesis, relaxation properties and in vivo assessment of a carborane-GdDOTA-monoamide conjugate as an MRI blood pool contrast agent." Organic & Biomolecular Chemistry 13, no. 33 (2015): 8912–18. http://dx.doi.org/10.1039/c5ob00876j.

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The synthesis, relaxivity measurements and in vivo assessment of CB-GdDOTA-MA amphiphilic conjugate as blood pool contrast agent (BPCA) is reported. This BPCA showed high relaxivity (r<sub>1</sub> = 6.8 mM<sup>−1</sup> s<sup>−1</sup> at 7 T in PBS) and exhibited excellent binding (87.4%) with HSA.
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Dissertations / Theses on the topic "Relaxivita"

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Botz, Alexandra. "Complexes peptide-lanthanide : vers de nouvelles sondes luminescentes et magnétiques de l'ADN." Thesis, Université Grenoble Alpes (ComUE), 2016. http://www.theses.fr/2016GREAV044.

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L’ADN est une molécule biologique essentielle, assurant le support et le transfert de l’information génétique des êtres vivants, et impliquée dans de nombreux processus d’interactions. L’élaboration d’outils moléculaires efficaces capables d’interagir avec l’ADN et de mettre en évidence cette interaction est donc un domaine de recherche d’intérêt majeur pour la compréhension d’événements biologiques essentiels et pour le diagnostic médical. Grâce à leurs propriétés spectroscopiques et magnétiques particulières, les ions lanthanides (Ln3+) s’avèrent être d’excellents candidats dans l’élaboratio
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Moula, Karimdjy Maria. "Nouveaux marqueurs à base de lanthanides pour l'imagerie moléculaire et l'analyse biomédicale." Thesis, Université Grenoble Alpes (ComUE), 2015. http://www.theses.fr/2015GREAV046/document.

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L'IRM (Imagerie par Résonance Magnétique) est une technique de choix pour l'imagerie moléculaire, soit la visualisation d'événements biologiques à l'échelle moléculaire. En effet, elle est non invasive et possède une haute résolution. Cependant, elle manque de sensibilité. L'utilisation d'agents de contraste commerciaux, qui sont pour la plupart des chélates de Gd(III), peut pallier à ce problème lors d'examens cliniques mais ils ne sont pas assez efficaces en vue de l'imagerie moléculaire. Leur efficacité, définie par leur relaxivité, peut être améliorée en optimisant les paramètres qui la go
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Messeri, Dimitri. "Targeted and high relaxivity contrast agents." Thesis, Durham University, 2001. http://etheses.dur.ac.uk/1246/.

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Chauvin, Thomas. "Développement d'agents de contraste intelligents pour l'Imagerie par Résonance Magnétique (IRM)." Thesis, Orléans, 2010. http://www.theses.fr/2010ORLE2011.

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L’Imagerie par Résonance Magnétique est une des techniques de diagnostic les plus performantes. Parmi les perspectives d’avenir, les applications en imagerie moléculaire avec l’utilisation d’agents de contraste intelligents sensibles à divers paramètres physico-chimiques sont particulièrement attrayantes.Dans cette thèse, nous présentons la synthèse et la caractérisation physico-chimique de nouveaux complexes de lanthanide dans le but de développer des agents de contraste sensibles à l’activité enzymatique ou la présence d’ions calcium. Les premiers complexes sont basés sur le concept de coupl
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Giardiello, Marco. "High relaxivity contrast agents for magnetic resonance imaging (MRI)." Thesis, University of Leicester, 2007. http://hdl.handle.net/2381/7701.

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The development of Gd(III)-based contrast agents for MRI applications has intensified in recent years due to the paramagnetic ion’s long electron spin relaxation time and large effective magnetic moment, µeff. Secondly, the exploitation of the long lived luminescent properties of the Ln(III) ions has lead to the development of luminescent lanthanide probes for sensing, time resolved immunoassay and imaging applications. Herein a series of novel Ln-DO3A based complexes are reported. Modulation of relaxivity, r1, (Gd) and emission intensity (Eu, Tb, Sm and Dy) has been achieved in three ways: Fi
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Wartenberg, Nicolas. "Développement de nano-traceurs à base d’organolanthanides pour applications biologiques et marquage de matériaux." Thesis, Lyon 1, 2012. http://www.theses.fr/2012LYO10224/document.

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Ce travail de thèse traite de l’élaboration de nanoparticules luminescentes à based’organolanthanides pour des applications d’imagerie biomédicale ou de marquage pour la lutte anticontrefaçon. Les organolanthanides ont été incorporés sans liaison covalente afin de préserver leursremarquables propriétés de luminescence et leur stabilité chimique. Deux types de nanoparticulesont été étudiés, des particules de latex et des billes de silice qui ont toutes les deux été synthétiséesen milieu hétérogène.La silice a été synthétisée par un procédé sol-gel en microémulsion inverse. Deux organolanthanide
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Haigh, Julian Saunders. "Investigation in to the Effect of Spin Locking on Contrast Agent Relaxivity." PDXScholar, 2015. http://pdxscholar.library.pdx.edu/open_access_etds/2496.

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The current trend in magnetic resonance imaging (MRI) is towards higher external magnetic field strengths (B0) to take advantage of increased sensitivity and signal to noise ratio (SNR). Unfortunately, as (B0) increases the effectiveness (relaxivity) of clinical gadolinium (Gd3+)-based contrast agents (CAs) administered to enhance image contrast is significantly reduced. Excellent soft tissue contrast can be generated with current agents despite their non-optimum relaxivities but necessitates large doses. The limits of detection of a CA at high B0 fields can be lowered by recovering the lost r
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Hsieh, Vivian Ph D. Massachusetts Institute of Technology. "High relaxivity biomolecule based contrast agents engineered for molecular functional magnetic resonance imaging." Thesis, Massachusetts Institute of Technology, 2016. http://hdl.handle.net/1721.1/104206.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Chemical Engineering, 2016.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (pages 71-84).<br>Magnetic resonance imaging (MRI) is a powerful neuroimaging tool that allows non-invasive visualization of the brain with high spatial and temporal resolution. Research on MRI contrast agents and their application to problems in neuroscience is burgeoning, and there is particular interest in developing MRI agents that are sensitive to time varying components of neurophysiology. Relatively recent advanc
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ABEY, JANE E. "SYNTHESIS, CHARACTERIZATION AND RELAXIVITY OF POLYMERIC GADOLINIUM CHELATES AS POTENTIAL MRI CONTRAST AGENTS." University of Cincinnati / OhioLINK, 2004. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1084460201.

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Michelin, Clement. "Synthèse de nouveaux agents bimodaux hydrosolubles pour l'IRM, l'imagerie nucléaire, l'imagerie biphotonique et la génération de second harmonique." Thesis, Dijon, 2015. http://www.theses.fr/2015DIJOS014/document.

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Le travail présenté dans ce mémoire de thèse avait pour but de synthétiser de nouveaux composés pour des applications en imagerie médicale. La première partie porte sur la synthèse de ligands hétéroleptiques pour la chélation de deux métaux différents en vue d’une utilisation dans deux types d’imagerie. Pour cela, nous avons d’abord synthétisé des porphyrines. Ces molécules sont connues pour la chélation de nombreux métaux de transition et notamment le cuivre, dont l’isotope cuivre-64 est un radioémetteur β+ utilisable en Tomographie par Émission de Positron (TEP). Ces porphyrines ont été coup
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Book chapters on the topic "Relaxivita"

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Tóth, Éva, Lothar Helm, and André E. Merbach. "Relaxivity of MRI Contrast Agents." In Topics in Current Chemistry. Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/3-540-45733-x_3.

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Tóth, éva, Lothar Helm, and André Merbach. "Relaxivity of Gadolinium(III) Complexes: Theory and Mechanism." In The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging. John Wiley & Sons, Ltd, 2013. http://dx.doi.org/10.1002/9781118503652.ch2.

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Serša, Igor. "Electric Current Detection by $$ T_{2}^{*} $$ Relaxivity Change: A Feasibility Study." In 8th European Medical and Biological Engineering Conference. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-64610-3_53.

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Sana, Barindra, and Sierin Lim. "Determining the Relaxivity Values of Protein Cage-Templated Nanoparticles Using Magnetic Resonance Imaging." In Methods in Molecular Biology. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-2131-7_4.

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"Relaxivity of Nanoparticles for Magnetic Resonance Imaging." In Handbook of Nanophysics. CRC Press, 2010. http://dx.doi.org/10.1201/9781420075496-32.

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"53 Contrast Media: Gd Chelates with Improved Relaxivity." In The Physics of Clinical MR Taught Through Images, edited by Val M. Runge, Wolfgang R. Nitz, and Johannes T. Heverhagen. Georg Thieme Verlag, 2018. http://dx.doi.org/10.1055/b-0038-163011.

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Conference papers on the topic "Relaxivita"

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Ashkar, Ayham, Quentin J. Fisher, and Carlos A. Grattoni. "Determination of Surface Relaxivity from NMR T2 Measurements." In GEO 2010. European Association of Geoscientists & Engineers, 2010. http://dx.doi.org/10.3997/2214-4609-pdb.248.342.

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Dastidar, Rahul, Carl H. Sondergeld, and Chandra Shekhar Rai. "NMR Desaturation and Surface Relaxivity Measurements on Clastics Rocks." In SPE Europec/EAGE Annual Conference and Exhibition. Society of Petroleum Engineers, 2006. http://dx.doi.org/10.2118/99629-ms.

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Sulucarnain, Ismail Dean, Carl H. Sondergeld, and Chandra Shekhar Rai. "An NMR Study of Shale Wettability and Effective Surface Relaxivity." In SPE Canadian Unconventional Resources Conference. Society of Petroleum Engineers, 2012. http://dx.doi.org/10.2118/162236-ms.

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Zhu, Chunxiao, Hugh Daigle, and Steven Bryant. "Nuclear Magnetic Resonance Investigation of Surface Relaxivity Modification by Paramagnetic Nanoparticles." In SPE Annual Technical Conference and Exhibition. Society of Petroleum Engineers, 2015. http://dx.doi.org/10.2118/175087-ms.

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Keating, Kristina. "The effect of inhomogeneous surface relaxivity on nuclear magnetic resonance relaxation rates." In SEG Technical Program Expanded Abstracts 2010. Society of Exploration Geophysicists, 2010. http://dx.doi.org/10.1190/1.3513674.

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Zhang, Boyang, and Hugh Daigle. "Direct Determination of Surface Relaxivity in Isolated Kerogen by Pulsed-Field Gradient NMR." In Unconventional Resources Technology Conference. American Association of Petroleum Geologists, 2016. http://dx.doi.org/10.15530/urtec-2016-2460364.

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Lundquist, Charles M., Christopher H. Loo, Aaron Mack, Jianhua Gu, Jim A. Bankson, and Rita E. Serda. "Porous Silicon-Superparamagnetic Iron Oxide Complexes and Impact on Negative Contrast Enhancement in MRI." In ASME 2013 2nd Global Congress on NanoEngineering for Medicine and Biology. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/nemb2013-93065.

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Purpose: Encapsulation of contrast agent within a nanoporous matrix has been shown to enhance contrast performance. Previous investigators have shown an up to 40-fold increase in T1 image contrast enhancement of gadolinium with encapsulation in carbon nanotubes. In this study we examined silicon encapsulation as a means of contrast enhancement in superparamagnetic iron oxide nanoparticles (SPIONs) using a particle-agarose phantom. Methods: 1μm discoidal pSi particles were loaded with 30 nm SPIONs through capillary action. Loaded particle preparations along with free SPION controls were homogen
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Dedourkova, T., O. Kaman, P. Veverka, et al. "Clusters of magnetic nanoparticles as contrast agents for MRI: The effect of aggregation on T2 relaxivity." In 2015 IEEE International Magnetics Conference (INTERMAG). IEEE, 2015. http://dx.doi.org/10.1109/intmag.2015.7156711.

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Mohnke, Oliver. "DERIVING NMR SURFACE RELAXIVITY AND PORE SIZE DISTRIBUTIONS BY NMR RELAXATION EXPERIMENTS ON PARTIALLY DE-SATURATED ROCKS." In Symposium on the Application of Geophysics to Engineering and Environmental Problems 2013. Environment and Engineering Geophysical Society, 2013. http://dx.doi.org/10.4133/sageep2013-192.1.

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Saidian*, Milad, Kurt Livo, and Manika Prasad. "Effect of Paramagnetic Mineral Content and Distribution on Surface Relaxivity in Organic-Rich Niobrara and Haynesville Shales." In SEG Technical Program Expanded Abstracts 2015. Society of Exploration Geophysicists, 2015. http://dx.doi.org/10.1190/segam2015-5863367.1.

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Reports on the topic "Relaxivita"

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Haigh, Julian. Investigation in to the Effect of Spin Locking on Contrast Agent Relaxivity. Portland State University Library, 2000. http://dx.doi.org/10.15760/etd.2493.

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