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Journal articles on the topic 'Relaxivita'

Author: Grafiati

Published: 4 June 2021

Last updated: 18 February 2022

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1

Sosnovsky, George, Shu Wen Li, N. Uma Maheswara Rao, and Robert C. Brasch. "Spin Labeled Chelating Agents and their Gadolinium Complexes as Contrast Enhancing Agents for NMR Imaging." Zeitschrift für Naturforschung B 40, no. 11 (1985): 1558–62. http://dx.doi.org/10.1515/znb-1985-1124.

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Spin labeled EDTA, CDTA and DTPA chelating agents and their gadolinium complexes were synthesized and evaluated for their effects on the spin-lattice (T1) and spin-spin (T2) relaxation times of water, plasma, and blood. It was found that the spin labeled chelating agents are effective proton relaxation agents. Although, the gadolinium complexes of these agents have superior relaxation properties, the differences in relaxivitv between the spin labeled complexes and the non-spin labeled gadolinium complexes are marginal. The spin labeled agents and their gadolinium complexes are expected to be v

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2

Jao, Jo-Chi, Po-Chou Chen, Yun-Ni Ting, Chia-Chi Hsiao, and Huay-Ben Pan. "THE IMPACT OF FACTOR TE ON THE MEASUREMENT OF T1 RELAXIVITY." Biomedical Engineering: Applications, Basis and Communications 20, no. 05 (2008): 277–85. http://dx.doi.org/10.4015/s1016237208000891.

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Relaxivity is a very important indicator to evaluate the signal enhancement caused by MRI contrast agents. Many factors can affect the relaxivity values. The aim of this study is to investigate the influence of factor TE in the curve-fitting equation for T1 measurements. A spin echo pulse sequence was used as the scanning method. The relaxivity of Gd -DTPA doped saline at a 1.5 T MR scanner was under investigation. Gd -DTPA is the most widely used MRI contrast agent nowadays. In this study, both computer simulations and phantom studies were performed. T1 values were calculated by using both sp

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3

Xiao, Yan-meng, Gui-yan Zhao, Xin-xiu Fang, et al. "A smart copper(ii)-responsive binuclear gadolinium(iii) complex-based magnetic resonance imaging contrast agent." RSC Adv. 4, no. 65 (2014): 34421–27. http://dx.doi.org/10.1039/c4ra04526b.

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The relaxivity of the complex was modulated by Cu<sup>2+</sup>, that is, in the absence of Cu<sup>2+</sup> the complex exhibited a relatively low relaxivity value of 6.40 mM<sup>−1</sup> s<sup>−1</sup>, while the addition of Cu<sup>2+</sup> triggered the relaxivity to 11.28 mM<sup>−1</sup> s<sup>−1</sup>, an enhancement of approximately 76%.

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4

Sigg, Severin J., Francesco Santini, Adrian Najer, Pascal U. Richard, Wolfgang P. Meier, and Cornelia G. Palivan. "Nanoparticle-based highly sensitive MRI contrast agents with enhanced relaxivity in reductive milieu." Chemical Communications 52, no. 64 (2016): 9937–40. http://dx.doi.org/10.1039/c6cc03396b.

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5

Antal, Iryna, Oliver Strbak, Iryna Khmara, et al. "MRI Relaxivity Changes of the Magnetic Nanoparticles Induced by Different Amino Acid Coatings." Nanomaterials 10, no. 2 (2020): 394. http://dx.doi.org/10.3390/nano10020394.

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In this study, we analysed the physico-chemical properties of positively charged magnetic fluids consisting of magnetic nanoparticles (MNPs) functionalised by different amino acids (AAs): glycine (Gly), lysine (Lys) and tryptophan (Trp), and the influence of AA–MNP complexes on the MRI relaxivity. We found that the AA coating affects the size of dispersed particles and isoelectric point, as well as the zeta potential of AA–MNPs differently, depending on the AA selected. Moreover, we showed that a change in hydrodynamic diameter results in a change to the relaxivity of AA–MNP complexes. On the

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6

Reeßing, Friederike, Sèvrin E. M. Huijsse, Rudi A. J. O. Dierckx, Ben L. Feringa, Ronald J. H. Borra, and Wiktor Szymański. "A Photocleavable Contrast Agent for Light-Responsive MRI." Pharmaceuticals 13, no. 10 (2020): 296. http://dx.doi.org/10.3390/ph13100296.

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Thanks to its innocuousness and high spatiotemporal resolution, light is used in several established and emerging applications in biomedicine. Among them is the modulation of magnetic resonance imaging (MRI) contrast agents’ relaxivity with the aim to increase the sensitivity, selectivity and amount of functional information obtained from this outstanding whole-body medical imaging technique. This approach requires the development of molecular contrast agents that show high relaxivity and strongly pronounced photo-responsiveness. To this end, we report here the design and synthesis of a light-

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7

Bryar, Traci R., and Rosemary J. Knight. "Laboratory studies of the effect of sorbed oil on proton nuclear magnetic resonance." GEOPHYSICS 68, no. 3 (2003): 942–48. http://dx.doi.org/10.1190/1.1581046.

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Proton NMR (nuclear magnetic resonance) measurements were made of T1 and T2 relaxation times of water in saturated sands containing varying amounts of sorbed oil on the grain surfaces. The porosity, surface area, and grain density of the sands and the relaxation times of the extracted pore water were also determined experimentally. Sorption of oil changed the relaxation time of water in the saturated sands through changes in surface area and surface relaxivity, the parameter used to quantify the ability of the surface of the pore space to reduce NMR relaxation times. In some cases the addition

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8

Zhu, Chunxiao, Hugh Daigle, and Steven L. Bryant. "Paramagnetic nanoparticles as nuclear magnetic resonance contrast agents in sandstone: Importance of nanofluid-rock interactions." Interpretation 4, no. 2 (2016): SF55—SF65. http://dx.doi.org/10.1190/int-2015-0137.1.

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Nuclear magnetic resonance has been applied in well logging to investigate pore size distribution with high resolution and accuracy based on the relaxation time distribution. However, due to the heterogeneity of natural rock, pore surface relaxivity, which links relaxation time and pore size, varies within the pore system. To analyze and alter pore surface relaxivity, we saturated Boise sandstone cores with positively charged zirconia nanoparticle dispersions in which nanoparticles can be adsorbed onto the sandstone pore wall, while negatively charged zirconia nanoparticles dispersions were us

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9

Fransen, Peter, Daniel Pulido, Lorena Simón-Gracia, et al. "r1andr2Relaxivities of Dendrons Based on a OEG-DTPA Architecture: Effect of Gd3+Placement and Dendron Functionalization." Journal of Nanotechnology 2015 (2015): 1–8. http://dx.doi.org/10.1155/2015/848020.

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In magnetic resonance imaging, contrast agents are employed to enhance the signal intensity. However, current commercial contrast agents are hindered by a low relaxivity constant. Dendrimers can be employed to create higher molecular weight contrast agents which have an increased relaxivity due to a lower molecular rotation. In this study, dendrimers containing DTPA derivatives as cores and/or branching units were used to chelate gadolinium ions. Locating the gadolinium ions inside the dendrimers results in higher relaxivity constants, possibly because the paramagnetic center is closer to the

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10

Goswami, Lalit N., Quanyu Cai, Lixin Ma, Satish S. Jalisatgi, and M. Frederick Hawthorne. "Synthesis, relaxation properties and in vivo assessment of a carborane-GdDOTA-monoamide conjugate as an MRI blood pool contrast agent." Organic & Biomolecular Chemistry 13, no. 33 (2015): 8912–18. http://dx.doi.org/10.1039/c5ob00876j.

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The synthesis, relaxivity measurements and in vivo assessment of CB-GdDOTA-MA amphiphilic conjugate as blood pool contrast agent (BPCA) is reported. This BPCA showed high relaxivity (r<sub>1</sub> = 6.8 mM<sup>−1</sup> s<sup>−1</sup> at 7 T in PBS) and exhibited excellent binding (87.4%) with HSA.

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11

Bruce, James I., Patrick J. O’Connell, Peter G. Taylor, David P. T. Smith, Roy C. Adkin, and Victoria K. Pearson. "Synthesis of Organosilicon Ligands for Europium (III) and Gadolinium (III) as Potential Imaging Agents." Molecules 25, no. 18 (2020): 4253. http://dx.doi.org/10.3390/molecules25184253.

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The relaxivity of MRI contrast agents can be increased by increasing the size of the contrast agent and by increasing concentration of the bound gadolinium. Large multi-site ligands able to coordinate several metal centres show increased relaxivity as a result. In this paper, an “aza-type Michael” reaction is used to prepare cyclen derivatives that can be attached to organosilicon frameworks via hydrosilylation reactions. A range of organosilicon frameworks were tested including silsesquioxane cages and dimethylsilylbenzene derivatives. Michael donors with strong electron withdrawing groups co

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12

Naber, Christoph, Florian Kleiner, Franz Becker, et al. "C-S-H Pore Size Characterization Via a Combined Nuclear Magnetic Resonance (NMR)–Scanning Electron Microscopy (SEM) Surface Relaxivity Calibration." Materials 13, no. 7 (2020): 1779. http://dx.doi.org/10.3390/ma13071779.

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A new method for the nuclear magnetic resonance (NMR) surface relaxivity calibration in hydrated cement samples is proposed. This method relies on a combined analysis of 28-d hydrated tricalcium silicate samples by scanning electron microscopy (SEM) image analysis and 1H-time-domain (TD)-NMR relaxometry. Pore surface and volume data for interhydrate pores are obtained from high resolution SEM images on surfaces obtained by argon broad ion beam sectioning. These data are combined with T2 relaxation times from 1H-TD-NMR to calculate the systems surface relaxivity according to the fast exchange m

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13

Liu, Guozhen, Nicholas M. K. Tse, Matthew R. Hill, Danielle F. Kennedy, and Calum J. Drummond. "Disordered Mesoporous Gadolinosilicate Nanoparticles Prepared Using Gadolinium Based Ionic Liquid Emulsions: Potential as Magnetic Resonance Imaging Contrast Agents." Australian Journal of Chemistry 64, no. 5 (2011): 617. http://dx.doi.org/10.1071/ch11064.

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Gadolinium doped mesoporous silica (gadolinosilicate) nanoparticles were synthesized using a novel approach aimed at incorporating Gd ions into a porous silica network. The ionic liquid, gadolinium (Z)-octadec-9-enoate (Gd Oleate) was utilized in a dual role, as a soft template to generate porous silica and also to act as a gadolinium source for incorporation into the silicate. The generated silicate materials were characterized for size, structure and composition, confirming that gadolinium was successfully doped into the silicate network in a mesoporous nanoparticulate form. Proton relaxivit

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14

Tandon, Saurabh, and Zoya Heidari. "Quantifying the Mechanisms Contributing to Nuclear-Magnetic-Resonance Surface Relaxation of Protons in Kerogen Pores of Organic-Rich Mudrocks." SPE Journal 24, no. 06 (2019): 2438–57. http://dx.doi.org/10.2118/197063-pa.

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Summary The evaluation of nuclear–magnetic–resonance (NMR) measurements can be challenging in organic–rich mudrocks because of their heterogeneity, tight pores, presence of kerogen, and the lack of understanding regarding the relaxation mechanism on the kerogen surface. Numerical simulation of NMR responses in the pore–scale domain in such complex rocks is also not very useful because most of the inputs are derived from conventional surface–relaxivity models. The conventional grain/fluid–interaction models for quantifying surface relaxivity do not account for any dipolar coupling in kerogen po

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15

Anzalone, Nicoletta. "Are All Gadolinium-based Contrast Agents Similar? The Importance of High Stability, High Relaxivity and High Concentration." European Neurological Review 4, no. 2 (2009): 98. http://dx.doi.org/10.17925/enr.2009.04.02.98.

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Gadolinium-based contrast agents (GBCAs) are commonly used to enhance image acquisition via magnetic resonance imaging, but they differ in their physicochemical characteristics and therefore their function. The stability, concentration and relaxivity of a GBCA can have a major impact on clinical efficacy. Stability is related to safety. GBCAs can be categorised into three stability classes: non-ionic linear agents, ionic linear agents and macrocyclic agents, in order of increasing stability. Relaxivity and concentration are contributing factors to the level of enhancement that can be achieved

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16

Ma, Ji, and Kezheng Chen. "Impact of metallic trace elements on relaxivities of iron-oxide contrast agents." RSC Advances 9, no. 53 (2019): 30932–36. http://dx.doi.org/10.1039/c9ra07227f.

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17

Dalas, Florent, Jean-Pierre Korb, Sylvie Pourchet, André Nonat, David Rinaldi, and Martin Mosquet. "Surface Relaxivity of Cement Hydrates." Journal of Physical Chemistry C 118, no. 16 (2014): 8387–96. http://dx.doi.org/10.1021/jp500055p.

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18

Peters, Joop A. "Relaxivity of manganese ferrite nanoparticles." Progress in Nuclear Magnetic Resonance Spectroscopy 120-121 (October 2020): 72–94. http://dx.doi.org/10.1016/j.pnmrs.2020.07.002.

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19

Wang, Zhao, Fabio Carniato, Yijun Xie, et al. "High Relaxivity Gadolinium-Polydopamine Nanoparticles." Small 13, no. 43 (2017): 1701830. http://dx.doi.org/10.1002/smll.201701830.

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20

Jang, Yeong-Ji, Shuwen Liu, Huan Yue, et al. "Hydrophilic Biocompatible Poly(Acrylic Acid-co-Maleic Acid) Polymer as a Surface-Coating Ligand of Ultrasmall Gd2O3 Nanoparticles to Obtain a High r1 Value and T1 MR Images." Diagnostics 11, no. 1 (2020): 2. http://dx.doi.org/10.3390/diagnostics11010002.

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The water proton spin relaxivity, colloidal stability, and biocompatibility of nanoparticle-based magnetic resonance imaging (MRI) contrast agents depend on the surface-coating ligands. Here, poly(acrylic acid-co-maleic acid) (PAAMA) (Mw = ~3000 amu) is explored as a surface-coating ligand of ultrasmall gadolinium oxide (Gd2O3) nanoparticles. Owing to the numerous carboxylic groups in PAAMA, which allow its strong conjugation with the nanoparticle surfaces and the attraction of abundant water molecules to the nanoparticles, the synthesized PAAMA-coated ultrasmall Gd2O3 nanoparticles (davg = 1.

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21

Orts-Arroyo, Marta, Amadeo Ten-Esteve, Sonia Ginés-Cárdenas, Isabel Castro, Luis Martí-Bonmatí, and José Martínez-Lillo. "A Gadolinium(III) Complex Based on the Thymine Nucleobase with Properties Suitable for Magnetic Resonance Imaging." International Journal of Molecular Sciences 22, no. 9 (2021): 4586. http://dx.doi.org/10.3390/ijms22094586.

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The paramagnetic gadolinium(III) ion is used as contrast agent in magnetic resonance (MR) imaging to improve the lesion detection and characterization. It generates a signal by changing the relaxivity of protons from associated water molecules and creates a clearer physical distinction between the molecule and the surrounding tissues. New gadolinium-based contrast agents displaying larger relaxivity values and specifically targeted might provide higher resolution and better functional images. We have synthesized the gadolinium(III) complex of formula [Gd(thy)2(H2O)6](ClO4)3·2H2O (1) [thy = 5-m

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22

Elistratova, Julia, Bulat Akhmadeev, Aidar Gubaidullin, et al. "Nanoscale hydrophilic colloids with high relaxivity and low cytotoxicity based on Gd(iii) complexes with Keplerate polyanions." New Journal of Chemistry 41, no. 13 (2017): 5271–75. http://dx.doi.org/10.1039/c7nj01237c.

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23

Ferreira, Miguel F., Janaina Gonçalves, Bibimaryam Mousavi, et al. "Gold nanoparticles functionalised with fast water exchanging Gd3+ chelates: linker effects on the relaxivity." Dalton Transactions 44, no. 9 (2015): 4016–31. http://dx.doi.org/10.1039/c4dt03210a.

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24

Li, Juan, Rongli Cui, Yanan Chang, et al. "Adaption of the structure of carbon nanohybrids toward high-relaxivity for a new MRI contrast agent." RSC Advances 6, no. 63 (2016): 58028–33. http://dx.doi.org/10.1039/c6ra06733f.

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25

Lin, Babao, Xiuzhong Yao, Yihua Zhu, Jianhua Shen, Xiaoling Yang, and Chunzhong Li. "Multifunctional gadolinium-labeled silica-coated core/shell quantum dots for magnetic resonance and fluorescence imaging of cancer cells." RSC Adv. 4, no. 40 (2014): 20641–48. http://dx.doi.org/10.1039/c4ra02424a.

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26

Wu, Changqiang, Danyang Li, Li Yang, et al. "Multivalent manganese complex decorated amphiphilic dextran micelles as sensitive MRI probes." Journal of Materials Chemistry B 3, no. 8 (2015): 1470–73. http://dx.doi.org/10.1039/c4tb02036g.

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27

Bonvin, Debora, Jessica A. M. Bastiaansen, Matthias Stuber, Heinrich Hofmann, and Marijana Mionić Ebersold. "Folic acid on iron oxide nanoparticles: platform with high potential for simultaneous targeting, MRI detection and hyperthermia treatment of lymph node metastases of prostate cancer." Dalton Transactions 46, no. 37 (2017): 12692–704. http://dx.doi.org/10.1039/c7dt02139a.

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28

Berwick, Matthew R., Louise N. Slope, Caitlin F. Smith, et al. "Location dependent coordination chemistry and MRI relaxivity, in de novo designed lanthanide coiled coils." Chemical Science 7, no. 3 (2016): 2207–16. http://dx.doi.org/10.1039/c5sc04101e.

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29

Ly, Joanne, Yuhuan Li, Mai N. Vu, et al. "Nano-assemblies of cationic mPEG brush block copolymers with gadolinium polyoxotungstate [Gd(W5O18)2]9− form stable, high relaxivity MRI contrast agents." Nanoscale 10, no. 15 (2018): 7270–80. http://dx.doi.org/10.1039/c8nr01544a.

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30

Liang, Guohai, and Lifu Xiao. "Gd3+-Functionalized gold nanoclusters for fluorescence–magnetic resonance bimodal imaging." Biomaterials Science 5, no. 10 (2017): 2122–30. http://dx.doi.org/10.1039/c7bm00608j.

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31

Xie, Xuan, and Chunfu Zhang. "Controllable Assembly of Hydrophobic Superparamagnetic Iron Oxide Nanoparticle with mPEG-PLA Copolymer and Its Effect on MR Transverse Relaxation Rate." Journal of Nanomaterials 2011 (2011): 1–7. http://dx.doi.org/10.1155/2011/152524.

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Assembly of individual superparamagnetic iron oxide nanoparticles (SPION) into cluster is an effective way to prepare MRI contrast agent with high relaxivity. In this study, we fabricated SPION clusters with different sizes and configurations by assembly of amphiphilic mPEG-PLA copolymer with hydrophobic SPION in aqueous solution. The evolution of cluster size and configuration with the amount of copolymer and the effect of cluster size on the transverse relaxivity was studied.T2relaxation rates of clusters with different sizes at iron concentration of 0.1 mM were compared with the theoretical

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32

Reeßing, F., M. C. A. Stuart, D. F. Samplonius, et al. "A light-responsive liposomal agent for MRI contrast enhancement and monitoring of cargo delivery." Chemical Communications 55, no. 72 (2019): 10784–87. http://dx.doi.org/10.1039/c9cc05516a.

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33

Xu, Weibing, Haitao Long, Xinxin Xu, Guorui Fu, Lumei Pu, and Lan Ding. "Poly(HPMA)-DTPA/DOTA-Gd conjugates for magnetic resonance imaging." New Journal of Chemistry 42, no. 24 (2018): 19344–48. http://dx.doi.org/10.1039/c8nj04355h.

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34

Wu, Changqiang, Li Yang, Zhuzhong Chen, et al. "Poly(ethylene glycol) modified Mn2+ complexes as contrast agents with a prolonged observation window in rat MRA." RSC Advances 7, no. 86 (2017): 54603–9. http://dx.doi.org/10.1039/c7ra09975d.

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35

Jin, Miao, Dominic E. M. Spillane, Carlos F. G. C. Geraldes, Gareth R. Williams, and S. W. Annie Bligh. "Gd(iii) complexes intercalated into hydroxy double salts as potential MRI contrast agents." Dalton Transactions 44, no. 47 (2015): 20728–34. http://dx.doi.org/10.1039/c5dt03433g.

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36

Gao, Duyang, Pengfei Zhang, Chengbo Liu, et al. "Compact chelator-free Ni-integrated CuS nanoparticles with tunable near-infrared absorption and enhanced relaxivity for in vivo dual-modal photoacoustic/MR imaging." Nanoscale 7, no. 42 (2015): 17631–36. http://dx.doi.org/10.1039/c5nr05237h.

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37

Bonvin, D., J. A. M. Bastiaansen, M. Stuber, H. Hofmann, and M. Mionić Ebersold. "ATP and NADPH coated iron oxide nanoparticles for targeting of highly metabolic tumor cells." Journal of Materials Chemistry B 5, no. 42 (2017): 8353–65. http://dx.doi.org/10.1039/c7tb01935a.

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38

Elistratova, Julia, Bulat Akhmadeev, Vladimir Korenev, et al. "Self-assembly of Gd3+-bound keplerate polyanions into nanoparticles as a route for the synthesis of positive MRI contrast agents. Impact of the structure on the magnetic relaxivity." Soft Matter 14, no. 38 (2018): 7916–25. http://dx.doi.org/10.1039/c8sm01214h.

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39

Lin, Ying, Sanxi Wang, Yajun Zhang, et al. "Ultra-high relaxivity iron oxide nanoparticles confined in polymer nanospheres for tumor MR imaging." Journal of Materials Chemistry B 3, no. 28 (2015): 5702–10. http://dx.doi.org/10.1039/c5tb00593k.

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40

Li, Jingchao, Yong Hu, Jia Yang, et al. "Facile synthesis of folic acid-functionalized iron oxide nanoparticles with ultrahigh relaxivity for targeted tumor MR imaging." Journal of Materials Chemistry B 3, no. 28 (2015): 5720–30. http://dx.doi.org/10.1039/c5tb00849b.

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41

Filippi, M., D. Remotti, M. Botta, E. Terreno, and L. Tei. "GdDOTAGA(C18)2: an efficient amphiphilic Gd(iii) chelate for the preparation of self-assembled high relaxivity MRI nanoprobes." Chemical Communications 51, no. 98 (2015): 17455–58. http://dx.doi.org/10.1039/c5cc06032j.

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42

Popov, A. L., M. A. Abakumov, I. V. Savintseva, et al. "Biocompatible dextran-coated gadolinium-doped cerium oxide nanoparticles as MRI contrast agents with high T1 relaxivity and selective cytotoxicity to cancer cells." Journal of Materials Chemistry B 9, no. 33 (2021): 6586–99. http://dx.doi.org/10.1039/d1tb01147b.

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Dextran-coated gadolinium-modified ceria nanoparticles possess excellent colloidal stability, high r1-relaxivity, demonstrate efficient cell internalisation and selective cytotoxicity to cancer cells.

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43

Cao, Yi, Min Liu, Ye Kuang, Guangyue Zu, Dangsheng Xiong та Renjun Pei. "A poly(ε-caprolactone)–poly(glycerol)–poly(ε-caprolactone) triblock copolymer for designing a polymeric micelle as a tumor targeted magnetic resonance imaging contrast agent". Journal of Materials Chemistry B 5, № 42 (2017): 8408–16. http://dx.doi.org/10.1039/c7tb01967j.

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Gadolinium-based macromolecular contrast agents (CAs) with favorable biocompatibility, targeting specificity, and high relaxivity properties are desired for magnetic resonance imaging (MRI) of tumors.

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44

Li, Xue, Ling Sun, Xiaoli Wei, et al. "Stimuli-responsive biodegradable and gadolinium-based poly[N-(2-hydroxypropyl) methacrylamide] copolymers: their potential as targeting and safe magnetic resonance imaging probes." Journal of Materials Chemistry B 5, no. 15 (2017): 2763–74. http://dx.doi.org/10.1039/c6tb03253b.

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45

Cho, Minjung, Richa Sethi, Jeyarama Subramanian Ananta narayanan, et al. "Gadolinium oxide nanoplates with high longitudinal relaxivity for magnetic resonance imaging." Nanoscale 6, no. 22 (2014): 13637–45. http://dx.doi.org/10.1039/c4nr03505d.

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46

Frangville, Camille, Maylis Gallois, Yichen Li, et al. "Hyperbranched polymer mediated size-controlled synthesis of gadolinium phosphate nanoparticles: colloidal properties and particle size-dependence on MRI relaxivity." Nanoscale 8, no. 7 (2016): 4252–59. http://dx.doi.org/10.1039/c5nr05064b.

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47

Wei, Ruixue, Tiantian Zhou, Chengjie Sun, et al. "Iron-oxide-based twin nanoplates with strong T2 relaxation shortening for contrast-enhanced magnetic resonance imaging." Nanoscale 10, no. 38 (2018): 18398–406. http://dx.doi.org/10.1039/c8nr04995e.

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48

Venkatesha, N., Yasrib Qurishi, Hanudatta S. Atreya, and Chandan Srivastava. "Effect of core–shell nanoparticle geometry on the enhancement of the proton relaxivity value in a nuclear magnetic resonance experiment." RSC Advances 6, no. 69 (2016): 64605–10. http://dx.doi.org/10.1039/c6ra11016a.

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49

Forgács, Attila, Lorenzo Tei, Zsolt Baranyai, David Esteban-Gómez, Carlos Platas-Iglesias, and Mauro Botta. "Optimising the relaxivities of Mn2+ complexes by targeting human serum albumin (HSA)." Dalton Transactions 46, no. 26 (2017): 8494–504. http://dx.doi.org/10.1039/c7dt01508a.

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50

Zheng, Xiao-Yu, Juan Pellico, Alexandr A. Khrapitchev, Nicola R. Sibson, and Jason J. Davis. "Dy-DOTA integrated mesoporous silica nanoparticles as promising ultrahigh field magnetic resonance imaging contrast agents." Nanoscale 10, no. 45 (2018): 21041–45. http://dx.doi.org/10.1039/c8nr07198e.

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