Log in

Relevant bibliographies by topics / Remnant cholesterol / Journal articles

To see the other types of publications on this topic, follow the link: Remnant cholesterol.

Journal articles on the topic 'Remnant cholesterol'

Author: Grafiati

Published: 23 August 2023

Last updated: 31 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Remnant cholesterol.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Sultan, F., D. Lagrange, X. Le Liepvre, and S. Griglio. "Chylomicron-remnant uptake by freshly isolated hepatocytes. Effect of heparin and of hepatic triacylglycerol lipase." Biochemical Journal 258, no. 2 (1989): 587–94. http://dx.doi.org/10.1042/bj2580587.

Full text

Abstract:

Chylomicron remnants labelled biologically with [3H]cholesterol were efficiently taken up by freshly isolated hepatocytes during a 3 h incubation in Krebs bicarbonate medium. Their [3H]cholesteryl ester was hydrolysed (74% net hydrolysis), and 0.1 mM-chloroquine could partially inhibit this hydrolysis, provided that hepatocytes were first preincubated for 2 h 30 min at 37 degrees C. This hydrolysis was also measured in preincubated cells with remnants double-labelled (3H and 14C) on their free cholesterol moiety; [3H]cholesterol arising from [3H]cholesteryl ester hydrolysis was recovered in th

APA, Harvard, Vancouver, ISO, and other styles

2

Redgrave, T. G., C. L. Elsegood, J. C. L. Mamo, and M. J. Callow. "Effects of hypothyroidism on the metabolism of lipid emulsion models of triacylglycerol-rich lipoproteins in rats." Biochemical Journal 273, no. 2 (1991): 375–81. http://dx.doi.org/10.1042/bj2730375.

Full text

Abstract:

Methimazole-treated hypothyroid rats were injected intravenously with triacylglycerol/cholesteryl oleate/cholesterol/phospholipid emulsions designed to model the composition of chylomicrons. Compared with controls, hypothyroidism decreased the clearance rates of emulsion cholesteryl oleate. Clearance of emulsion triolein was affected much less and could be accounted for by residual triolein in remnants, suggesting that triacylglycerol lipolysis by lipoprotein lipase was unaffected by hypothyroidism but that clearance of remnants from plasma was decreased. Assays in vitro showed increased activ

APA, Harvard, Vancouver, ISO, and other styles

3

WATTS, G. F., D. C. F. CHAN, P. H. R. BARRETT, I. J. MARTINS, and T. G. REDGRAVE. "Preliminary experience with a new stable isotope breath test for chylomicron remnant metabolism: a study in central obesity." Clinical Science 101, no. 6 (2001): 683–90. http://dx.doi.org/10.1042/cs1010683.

Full text

Abstract:

We aimed to investigate the metabolism of chylomicron remnants in the postabsorptive state employing a new stable isotope breath test in centrally obese men without overt hyperlipidaemia. Groups of 12 centrally obese and 12 non-obese men of similar age and with similar plasma cholesterol and triacylglycerol (triglyceride) levels were studied. The catabolism of chylomicron remnants was measured using an intravenous injection of a remnant-like emulsion containing cholesteryl [13C]oleate. Isotopic enrichment of 13CO2 in breath was determined using isotope-ratio mass spectrometry, and a multi-comp

APA, Harvard, Vancouver, ISO, and other styles

4

Chan, Dick C., Gerald F. Watts, P. Hugh Barrett, John CL Mamo, and Trevor G. Redgrave. "Markers of Triglyceride-rich Lipoprotein Remnant Metabolism in Visceral Obesity." Clinical Chemistry 48, no. 2 (2002): 278–83. http://dx.doi.org/10.1093/clinchem/48.2.278.

Full text

Abstract:

Abstract Background: Triglyceride-rich lipoprotein remnants are atherogenic, and this may be particularly important in visceral obesity. We investigated remnant metabolism in obese men by measuring remnant-like particle-cholesterol (RLP-C), apolipoprotein (apo) B-48, apoC-III, and the clearance of a labeled remnant-like emulsion. Methods: Fasting RLP-C, apoB-48, and apoC-III concentrations were measured in 48 viscerally obese men and 10 lean controls. RLP-C was determined by immunoseparation assay, apoB-48 by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and enhanced chemiluminesce

APA, Harvard, Vancouver, ISO, and other styles

5

Bowler, A., T. G. Redgrave, and J. C. L. Mamo. "Chylomicron-remnant clearance in homozygote and heterozygote Watanabe-heritable-hyperlipidaemic rabbits is defective. Lack of evidence for an independent chylomicron-remnant receptor." Biochemical Journal 276, no. 2 (1991): 381–86. http://dx.doi.org/10.1042/bj2760381.

Full text

Abstract:

Lymph chylomicrons radiolabelled in triacylglycerol and cholesteryl ester were injected into control and Watanabe heritable-hyperlipidaemic (WHHL) rabbits. Clearance of chylomicrons was slower in heterozygote and homozygote WHHL rabbits. Slower remnant clearance in WHHL rabbits was confirmed by monitoring the clearance from plasma of preformed chylomicron remnants. Use of chylomicron-like lipid emulsions injected into control and WHHL rabbits also confirmed the defect in remnant clearance in heterozygote WHHL and homozygote WHHL groups. Clearance from plasma of emulsion triolein was delayed in

APA, Harvard, Vancouver, ISO, and other styles

6

McPherson, Ruth. "Remnant Cholesterol." Journal of the American College of Cardiology 61, no. 4 (2013): 437–39. http://dx.doi.org/10.1016/j.jacc.2012.11.009.

Full text

APA, Harvard, Vancouver, ISO, and other styles

7

Langsted, Anne, Anne Marie Reimer Jensen, Anette Varbo, and Børge G. Nordestgaard. "Low High-Density Lipoprotein Cholesterol to Monitor Long-Term Average Increased Triglycerides." Journal of Clinical Endocrinology & Metabolism 105, no. 4 (2019): e1657-e1666. http://dx.doi.org/10.1210/clinem/dgz265.

Full text

Abstract:

Abstract Context Increased triglyceride-rich remnants represent a causal risk factor for ischemic cardiovascular disease. Objective We tested the hypothesis that low high-density lipoprotein (HDL) cholesterol can be used to monitor long-term high triglycerides/remnant cholesterol, just as high hemoglobin A1c (HbA1c) can be used to monitor long-term high glucose levels. Design, Setting, Participants, and Interventions We studied cross-sectionally 108 731 individuals, dynamically 1313 individuals with lipid measurement at 10 repeated visits, short-term 305 individuals during a fat load, and long

APA, Harvard, Vancouver, ISO, and other styles

8

Lambert, M. S., K. M. Botham, and P. A. Mayes. "Variations in composition of dietary fats affect hepatic uptake and metabolism of chylomicron remnants." Biochemical Journal 310, no. 3 (1995): 845–52. http://dx.doi.org/10.1042/bj3100845.

Full text

Abstract:

The hepatic metabolism of [1-14C]oleate- and [1,2-3H]cholesterol-dual-labelled chylomicron remnants derived from olive, corn, palm and fish oil and butter fat was compared by adding each lipoprotein separately to the perfusate of isolated livers from rats fed on a normal diet. Labelled remnants from butter fat and fish oil were removed more rapidly from the perfusate than remnants derived from olive, corn and palm oil. The oxidation of labelled remnant fatty acid from olive oil, fish oil or butter fat was four to seven times greater than that from corn and palm oil. Labelled fatty acid in fish

APA, Harvard, Vancouver, ISO, and other styles

9

Miyauchi, Kazuhito, Norihiko Kayahara, Masato Ishigami, et al. "Development of a Homogeneous Assay to Measure Remnant Lipoprotein Cholesterol." Clinical Chemistry 53, no. 12 (2007): 2128–35. http://dx.doi.org/10.1373/clinchem.2007.092296.

Full text

Abstract:

Abstract Background: Quantification of triglyceride-rich lipoprotein (TRL) remnants is useful for risk assessment of coronary artery disease and the diagnosis of type III hyperlipoproteinemia. Although an immunoseparation procedure for remnant-like particle cholesterol has been evaluated extensively in recent years, available methods for measuring TRL remnants have not achieved wide use in routine laboratory practice, suggesting a need for a homogeneous assay that can measure TRL remnant cholesterol in serum or plasma without pretreatment. Methods: We screened for suitable surfactants that exh

APA, Harvard, Vancouver, ISO, and other styles

10

CHAN, Dick C., Gerald F. WATTS, P. Hugh R. BARRETT, Frans H. O'NEILL, Trevor G. REDGRAVE, and Gilbert R. THOMPSON. "Relationships between cholesterol homoeostasis and triacylglycerol-rich lipoprotein remnant metabolism in the metabolic syndrome." Clinical Science 104, no. 4 (2003): 383–88. http://dx.doi.org/10.1042/cs1040383.

Full text

Abstract:

The dysmetabolic syndrome of insulin resistance and visceral obesity is characterized by elevated plasma concentration of triacylglycerol-rich lipoprotein (TRL) remnants that may be related to increased cardiovascular risk. Perturbed hepato-intestinal cholesterol metabolism may play a contributory role in this abnormality. We therefore investigated the association between plasma markers of cholesterol absorption and synthesis with TRL remnant metabolism in 35 men with the metabolic syndrome (MS). Plasma campesterol:cholesterol and lathosterol:cholesterol ratios were measured as estimates of ch

APA, Harvard, Vancouver, ISO, and other styles

11

Bravo, E., and M. Napolitano. "Mechanisms involved in chylomicron remnant lipid uptake by macrophages." Biochemical Society Transactions 35, no. 3 (2007): 459–63. http://dx.doi.org/10.1042/bst0350459.

Full text

Abstract:

Although it is clear that chylomicron remnants are atherogenic, events leading to their internalization by macrophages are still debated. The lack of apoE (apolipoprotein E) in CRLPs (chylomicron remnant-like particles) reduces macrophage TAG (triacylglycerol) content by approx. 50%, suggesting that, as well as apoE-mediated endocytic uptake, apoE receptor-independent mechanisms are involved in the induction of foam cells by chylomicron remnants. Evaluation of the radioactivity associated with macrophages after incubation with CRLPs containing radiolabelled lipids suggests that the TAG and cho

APA, Harvard, Vancouver, ISO, and other styles

12

Yang, Na, Miao Wang, Jing Liu, Jun Liu, Yongchen Hao, and Dong Zhao. "The Level of Remnant Cholesterol and Implications for Lipid-Lowering Strategy in Hospitalized Patients with Acute Coronary Syndrome in China: Findings from the Improving Care for Cardiovascular Disease in China—Acute Coronary Syndrome Project." Metabolites 12, no. 10 (2022): 898. http://dx.doi.org/10.3390/metabo12100898.

Full text

Abstract:

Elevated remnant cholesterol is associated with an increased risk of atherosclerotic cardiovascular disease (ASCVD). We aimed to evaluate the concentrations and general distribution of remnant cholesterol at admission in patients hospitalized for acute coronary syndrome (ACS), and those in patients who reached the low-density lipoprotein cholesterol (LDL-C) target or non-high-density lipoprotein cholesterol (non-HDL-C) target. Patients with ACS who were enrolled in the Improving Care for Cardiovascular Disease in China—ACS project from 2014 to 2019 were included. Elevated remnant cholesterol c

APA, Harvard, Vancouver, ISO, and other styles

13

Elshazly, Mohamed B., Preethi Mani, Steven Nissen, et al. "Remnant cholesterol, coronary atheroma progression and clinical events in statin-treated patients with coronary artery disease." European Journal of Preventive Cardiology 27, no. 10 (2019): 1091–100. http://dx.doi.org/10.1177/2047487319887578.

Full text

Abstract:

Aim Remnant cholesterol has been proposed to promote atherosclerotic cardiovascular disease independent of low-density lipoprotein cholesterol, yet the underlying mechanisms are not well understood. We aimed to study the association of remnant cholesterol with coronary atheroma progression and clinical events. Methods We analyzed data from 5754 patients with coronary artery disease undergoing serial intravascular ultrasonography who were enrolled in 10 trials examining various medical therapies. Remnant cholesterol was calculated as (non-high-density lipoprotein cholesterol – low-density lipop

APA, Harvard, Vancouver, ISO, and other styles

14

Kaysen, G. A., L. Mehendru, X. M. Pan, and I. Staprans. "Both peripheral chylomicron catabolism and hepatic uptake of remnants are defective in nephrosis." American Journal of Physiology-Renal Physiology 263, no. 2 (1992): F335—F341. http://dx.doi.org/10.1152/ajprenal.1992.263.2.f335.

Full text

Abstract:

We showed previously that proteinuria caused delayed chylomicron (CM) clearance in the rat and postulated the existence of a primary defect in CM hydrolysis. It was possible that reduced CM clearance resulted from increased lipogenesis causing saturation of catabolic sites and not from a primary defect in CM catabolism. To clarify this point we measured kinetically the absolute rate of triglyceride (TG) uptake from CM in rats with Heymann nephritis (HN) and normal Sprague-Dawley rats (SD) and determined TG uptake in individual tissues using [3H]TG- and [14C]cholesterol-labeled CM. Hepatic [14C

APA, Harvard, Vancouver, ISO, and other styles

15

Lippiello, P. M., P. J. Sisson, and M. Waite. "The uptake and metabolism of chylomicron-remnant lipids by rat liver parenchymal and non-parenchymal cells in vitro." Biochemical Journal 232, no. 2 (1985): 395–401. http://dx.doi.org/10.1042/bj2320395.

Full text

Abstract:

The uptake and metabolism of chylomicron-remnant lipids by individual liver cell types was examined by incubating remnants with monolayer cultures of hepatocytes, Kupffer cells, and endothelial cells from rat liver. Remnants were prepared in vitro from radiolabelled mesenteric-lymph chylomicra, utilizing either purified lipoprotein lipase from bovine milk, or plasma isolated from heparinized rats. The resulting particles contained [3H]phosphatidylcholine and cholesterol, and [14C]oleate in the acylglycerol, phospholipid, fatty-acid and cholesterol-ester fractions. The capacities of the three c

APA, Harvard, Vancouver, ISO, and other styles

16

Morise, Anthony P., Jennifer Tennant, Sari D. Holmes, and Danyel H. Tacker. "The Effect of Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors on Nonfasting Remnant Cholesterol in a Real World Population." Journal of Lipids 2018 (July 19, 2018): 1–8. http://dx.doi.org/10.1155/2018/9194736.

Full text

Abstract:

Background. Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors have demonstrated significant effects on low-density lipoprotein (LDL) cholesterol and nonhigh density lipoprotein (HDL) cholesterol. To date, there have been limited reports on the effect of PCSK9 inhibitors on remnant cholesterol. Objectives. Assess the effect of PCSK9 inhibitors on nonfasting remnant cholesterol in a real world population. Identify whether pretreatment triglyceride levels are associated with PCSK9 inhibition success as indicated by changes in remnant cholesterol levels. Methods. Patients in our adu

APA, Harvard, Vancouver, ISO, and other styles

17

Jepsen, Anne-Marie K., Anne Langsted, Anette Varbo, Lia E. Bang, Pia R. Kamstrup, and Børge G. Nordestgaard. "Increased Remnant Cholesterol Explains Part of Residual Risk of All-Cause Mortality in 5414 Patients with Ischemic Heart Disease." Clinical Chemistry 62, no. 4 (2016): 593–604. http://dx.doi.org/10.1373/clinchem.2015.253757.

Full text

Abstract:

Abstract BACKGROUND Increased concentrations of remnant cholesterol are causally associated with increased risk of ischemic heart disease. We tested the hypothesis that increased remnant cholesterol is a risk factor for all-cause mortality in patients with ischemic heart disease. METHODS We included 5414 Danish patients diagnosed with ischemic heart disease. Patients on statins were not excluded. Calculated remnant cholesterol was nonfasting total cholesterol minus LDL and HDL cholesterol. During 35836 person-years of follow-up, 1319 patients died. RESULTS We examined both calculated and direc

APA, Harvard, Vancouver, ISO, and other styles

18

Varbo, Anette, Jacob J. Freiberg, and Børge G. Nordestgaard. "Extreme Nonfasting Remnant Cholesterol vs Extreme LDL Cholesterol as Contributors to Cardiovascular Disease and All-Cause Mortality in 90000 Individuals from the General Population." Clinical Chemistry 61, no. 3 (2015): 533–43. http://dx.doi.org/10.1373/clinchem.2014.234146.

Full text

Abstract:

Abstract BACKGROUND Increased nonfasting remnant cholesterol, like increased LDL cholesterol, is causally associated with increased risk for ischemic heart disease (IHD). We tested the hypothesis that extreme concentrations of nonfasting remnant and LDL cholesterol are equal contributors to the risk of IHD, myocardial infarction (MI), and all-cause mortality. METHODS We compared stepwise increasing concentrations of nonfasting remnant and LDL cholesterol for association with risk of IHD, MI, and all-cause mortality in approximately 90 000 individuals from the Danish general population. During

APA, Harvard, Vancouver, ISO, and other styles

19

Rowsathien, Sathienwit, Krisada Sastravaha, Prajongjit Chamsaard, and Prin Vathesatogkit. "Correlation between Levels of Remnant Cholesterol versus LDL, A Cross-Sectional study." International Journal of Scientific Research and Management 10, no. 12 (2022): 740–63. http://dx.doi.org/10.18535/ijsrm/v10i12.mp02.

Full text

Abstract:

Background: High levels of LDL cholesterol were directly related to the risk of atherosclerosis, metabolic diseases, and cardiovascular complications. However, in some groups of patients with low levels, they were also found. Lead to the risk of other lipid components, including Remnant cholesterol. A recent study found related to cardiovascular risk as well. Currently, no direct comparison between Remnant cholesterol and LDL cholesterol level. Objective: To study the correlation between Remnant cholesterol and LDL levels both in fasting and non-fasting states with the medical conditions

APA, Harvard, Vancouver, ISO, and other styles

20

Varbo, Anette, Jacob J. Freiberg, and Børge G. Nordestgaard. "Remnant Cholesterol and Myocardial Infarction in Normal Weight, Overweight, and Obese Individuals from the Copenhagen General Population Study." Clinical Chemistry 64, no. 1 (2018): 219–30. http://dx.doi.org/10.1373/clinchem.2017.279463.

Full text

Abstract:

Abstract BACKGROUND We tested whether high remnant cholesterol is associated with high myocardial infarction risk, independent of whether an individual is normal weight, overweight, or obese. METHODS A total of 106216 individuals from the Copenhagen General Population Study were followed for up to 11 years, during which 1565 experienced a myocardial infarction. Individuals were grouped by clinically meaningful remnant cholesterol concentrations of &lt;0.5 mmol/L (19 mg/dL), 0.5 to 0.99 mmol/L (19–38 mg/dL), 1.0 to 1.49 mmol/L (39–58 mg/dL), and ≥1.5 mmol/L (58 mg/dL), and by body mass inde

APA, Harvard, Vancouver, ISO, and other styles

21

Mansbach, C. M., and R. F. Dowell. "Role of the intestine in chylomicron remnant clearance." American Journal of Physiology-Gastrointestinal and Liver Physiology 269, no. 1 (1995): G144—G152. http://dx.doi.org/10.1152/ajpgi.1995.269.1.g144.

Full text

Abstract:

When 810 mumol of [3H]glyceryl trioleate (TO) were infused intraduodenally over 6 h into rats, 29% of the triacylglycerol (TG) acyl groups in the mucosa were not from the infusate. We tested the hypothesis that chylomicron remnants contribute to the mucosal pool of nondietary TG acyl groups, since the acyl group composition of the chylomicron remnants was 58% oleate, compared with 90% in their parent chylomicrons. Purified 3H-labeled remnants were generated from chylomicrons formed in rats receiving TO intraduodenally, with 95% of the remnant disintegrations per minute (dpm) being in TG. The 3

APA, Harvard, Vancouver, ISO, and other styles

22

NAPOLITANO, Mariarosaria, Kelly V. BATT, Michael AVELLA, Elena BRAVO, and Kathleen M. BOTHAM. "Lipid synthesis in macrophages derived from the human cell line THP-1: modulation of the effects of native and oxidized chylomicron-remnant-like particles by oestrogen." Clinical Science 101, no. 4 (2001): 403–13. http://dx.doi.org/10.1042/cs1010403.

Full text

Abstract:

The effects of native and oxidized chylomicron remnants on the synthesis of cholesteryl ester and triacylglycerol in macrophages, and the way that this is influenced by exposure of the cells to oestrogen, was investigated using the human monocyte cell line THP-1 and chylomicron-remnant-like particles containing human apolipoprotein E (CRLPs). Synthesis of the lipids was measured by the incorporation of [3H]oleate into cholesteryl ester and triacylglycerol. CRLPs (5-40μg of cholesterol/ml) containing either trilinolein or triolein as the triacylglycerol component caused a dose-dependent decreas

APA, Harvard, Vancouver, ISO, and other styles

23

Pan, Deng, Lin Xu, Li-Xiao Zhang, Da-Zhuo Shi, and Ming Guo. "Associations between remnant cholesterol levels and mortality in patients with diabetes." World Journal of Diabetes 15, no. 4 (2024): 712–23. http://dx.doi.org/10.4239/wjd.v15.i4.712.

Full text

Abstract:

BACKGROUND Dyslipidemia is frequently present in patients with diabetes. The associations of remnant cholesterol and mortality remains unclear in patients with diabetes. AIM To explore the associations of remnant cholesterol with all-cause and cardiovascular mortality in patients with diabetes. METHODS This prospective cohort study included 4740 patients with diabetes who participated in the National Health and Nutrition Examination Survey from 1999 through 2018. Remnant cholesterol was used as the exposure variable, and all-cause and cardiovascular mortality were considered outcome events. Ou

APA, Harvard, Vancouver, ISO, and other styles

24

Baratta, Francesco, Nicholas Cocomello, Mattia Coronati, et al. "Cholesterol Remnants, Triglyceride-Rich Lipoproteins and Cardiovascular Risk." International Journal of Molecular Sciences 24, no. 5 (2023): 4268. http://dx.doi.org/10.3390/ijms24054268.

Full text

Abstract:

Randomized clinical trials with statins and other lipid-lowering drugs have shown the presence of a “residual cardiovascular risk” in those treated to “target” for LDL-cholesterol. This risk is mainly associated to lipid components other than LDL and in particular to remnant cholesterol (RC) and to lipoproteins rich in triglycerides in fasting and non-fasting conditions. During fasting, RCs correspond to the cholesterol content of the VLDL and their partially depleted triglyceride remnant containing apoB-100. Conversely, in non-fasting conditions, RCs include also cholesterol present in chylom

APA, Harvard, Vancouver, ISO, and other styles

25

Nnamdi, Chinonso, Amah Ubuo, Anaelechi Onuegbu, et al. "Remnant Cholesterol and Leptin: Any Association in Normal Weight, Over Weight and Obese Individuals in South East Nigeria." ULUTAS MEDICAL JOURNAL 8, no. 4 (2022): 135. http://dx.doi.org/10.5455/umj.20220616022839.

Full text

Abstract:

Introduction: Leptin circulating levels increase with weight gain and decrease with weight loss. The amount of leptin circulating in the body is proportional to an individual's fat. We investigated the association of leptin and remnant cholesterol in normal-weight, overweight and obese participants in southeast Nigeria. Materials and Methods: This is a cross-sectional random study. A total of 90 healthy obese, overweight, and normal-weight participants who met the inclusion criteria were randomly enrolled in the study. They were grouped using their body mass index of 18.5 to 24.9 kg/m2 (averag

APA, Harvard, Vancouver, ISO, and other styles

26

Wang, Jeffrey, Maaike Kockx, Gabrielle J. Pennings, Tim Lambert, Vincent Chow, and Leonard Kritharides. "Discordance Between Triglycerides, Remnant Cholesterol and Systemic Inflammation in Patients with Schizophrenia." Biomedicines 12, no. 12 (2024): 2884. https://doi.org/10.3390/biomedicines12122884.

Full text

Abstract:

Background/Objectives: Hypertriglyceridaemia and systemic inflammation are prevalent in patients with schizophrenia and contribute to an increased risk of cardiovascular disease. Although elevated triglycerides (TGs) and remnant cholesterol are linked to inflammation in the general population and individuals with metabolic syndrome, whether they are associated in patients with schizophrenia remains unclear. Methods: Fasting levels of TG, cholesterol (total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and remnant cholesterol)), and

APA, Harvard, Vancouver, ISO, and other styles

27

Öörni, Katariina, Satu Lehti, Peter Sjövall, and Petri T. Kovanen. "Triglyceride-Rich Lipoproteins as a Source of Proinflammatory Lipids in the Arterial Wall." Current Medicinal Chemistry 26, no. 9 (2019): 1701–10. http://dx.doi.org/10.2174/0929867325666180530094819.

Full text

Abstract:

Apolipoprotein B –containing lipoproteins include triglyceride-rich lipoproteins (chylomicrons and their remnants, and very low-density lipoproteins and their remnants) and cholesterol-rich low-density lipoprotein particles. Of these, lipoproteins having sizes below 70-80 nm may enter the arterial wall, where they accumulate and induce the formation of atherosclerotic lesions. The processes that lead to accumulation of lipoprotein-derived lipids in the arterial wall have been largely studied with a focus on the low-density lipoprotein particles. However, recent observational and genetic studie

APA, Harvard, Vancouver, ISO, and other styles

28

Twickler, T. B., G. M. Dallinga-Thie, J. S. Cohn, and M. J. Chapman. "Elevated Remnant-Like Particle Cholesterol Concentration." Circulation 109, no. 16 (2004): 1918–25. http://dx.doi.org/10.1161/01.cir.0000125278.58527.f3.

Full text

APA, Harvard, Vancouver, ISO, and other styles

29

Varbo, Anette, and Børge G. Nordestgaard. "Remnant cholesterol and ischemic heart disease." Current Opinion in Lipidology 25, no. 4 (2014): 266–73. http://dx.doi.org/10.1097/mol.0000000000000093.

Full text

APA, Harvard, Vancouver, ISO, and other styles

30

Mearns, Bryony M. "Role of remnant cholesterol in IHD." Nature Reviews Cardiology 10, no. 10 (2013): 553. http://dx.doi.org/10.1038/nrcardio.2013.132.

Full text

APA, Harvard, Vancouver, ISO, and other styles

31

Kuznetsova, A. S. "Interrelationship of dyslipidemia with indicators of regional hemodynamics in patients with atherosclerosis of the visceral branches of the abdominal aorta." Regional blood circulation and microcirculation 15, no. 3 (2016): 44–49. http://dx.doi.org/10.24884/1682-6655-2016-15-3-44-49.

Full text

Abstract:

Introduction and aim - to determine the relationship of dyslipidemia and endothelial shear rate in the unpaired visceral arteries in patients with atherosclerosis in the abdominal aorta pool. Mathereals and methods. The study included 50 people. All patients were examined by a single protocol. Conduct a full clinical-laboratory and instrumental examination, supplemented by the following laboratory parameters: total cholesterol (TC), triglycerides, HDL, LDL, apolipoprotein A1, apolipoprotein B, Remnant cholesterol calculated using the formula: total cholesterol - (HDL+LDL). All patients underwe

APA, Harvard, Vancouver, ISO, and other styles

32

Chinonso, Nnamdi J., Ubuo K. Amah, Onuegbu J. Anaelechi, et al. "Comparative Study of Remnant Cholesterol, Some Lipid Fractions and FBS Level in Overweight and Obese Participants in South East Nigeria." Asian Journal of Research in Biochemistry 12, no. 3 (2023): 11–19. http://dx.doi.org/10.9734/ajrb/2023/v12i3235.

Full text

Abstract:

Background: Obesity is one of the characteristics of metabolic disorders, it has been linked to cardiovascular diseases. Remnant cholesterol has been proposed to be a link between obesity and coronary heart disease, thus a risk factor for the development of cardiovascular disease in obese people. We compared the level of calculated non-fasting remnant cholesterol, fasting and non-fasting lipid profile and fasting blood sugar in overweight, obese and normal weight participants in Nnewi, a town in South East Nigeria. Methods: In this cross-sectional study, a total of 90 apparently healthy

APA, Harvard, Vancouver, ISO, and other styles

33

Farjam, Mojtaba, Masoumeh Kheirandish, Amin Ghanbarnejad, et al. "Reference Interval for Non-HDL-Cholesterol, Remnant Cholesterol and Other Lipid Parameters in the Southern Iranian Population; Findings From Bandare Kong and Fasa Cohort Studies." Archives of Iranian Medicine 27, no. 1 (2024): 15–22. http://dx.doi.org/10.34172/aim.2024.03.

Full text

Abstract:

Background: Growing evidence shows the undisputable role of non-HDL-C and remnant cholesterol (remnant-C) in cardiovascular disease (CVD) risk assessment and treatment. However, the reference interval (RI) for these lipid parameters is not readily available. The aim of the present investigation was to determine the age and sex-specific RIs for non-HDL-C and remnant-C as well as other lipid parameters among a healthy population in southern Iran. We also report the RI of lipid parameters in rural and urban residents, smokers and post-menopausal women. Methods: Among 14063 participants of Bandare

APA, Harvard, Vancouver, ISO, and other styles

34

Packard, Chris J. "Remnants, LDL, and the Quantification of Lipoprotein-Associated Risk in Atherosclerotic Cardiovascular Disease." Current Atherosclerosis Reports 24, no. 3 (2022): 133–42. http://dx.doi.org/10.1007/s11883-022-00994-z.

Full text

Abstract:

Abstract Purpose of Review Implementation of intensive LDL cholesterol (LDL-C) lowering strategies and recognition of the role of triglyceride-rich lipoproteins (TRL) in atherosclerosis has prompted re-evaluation of the suitability of current lipid profile measurements for future clinical practice. Recent Findings At low concentrations of LDL-C (< 1.8 mmol/l/70 mg/dl), the Friedewald equation yields estimates with substantial negative bias. New equations provide a more accurate means of calculating LDL-C. Recent reports indicate that the increase in risk per unit increment in TRL/remnant ch

APA, Harvard, Vancouver, ISO, and other styles

35

Carrella, Massimino, Annalisa Csillaghy, Renato de Mercato, and Agesilao D'Arienzo. "Biliary Excretion of Chylomicron Remnant Cholesterol in the Rat: Responses to the Expansion of Their Plasma Pool and Promoting Role of Stimulated Bile-Acid Synthesis." Clinical Science 89, no. 2 (1995): 121–28. http://dx.doi.org/10.1042/cs0890121.

Full text

Abstract:

1. Chylomicron remnants, the intermediate intestinal lipoproteins carrying the bulk of dietary cholesterol, are actively taken up and degraded in the hepatocytes, releasing cholesterol which can be excreted in bile. To study this pathway, a mass of remnants, leading to a consistent rise in hepatic cholesterol, was administered as an intravenous bolus in rats with chronic bile fistula equilibrated by water, electrolyte and taurocholate infusions, and changes in biliary lipids and bile acids were evaluated for up to 24 h in comparison with baseline. 2. A mean 16% increase in the net output of bi

APA, Harvard, Vancouver, ISO, and other styles

36

Langsted, A., C. M. Madsen, and B. G. Nordestgaard. "Contribution of remnant cholesterol to cardiovascular risk." Journal of Internal Medicine 288, no. 1 (2020): 116–27. http://dx.doi.org/10.1111/joim.13059.

Full text

APA, Harvard, Vancouver, ISO, and other styles

37

Yakhimovich, Yana. "Remnant cholesterol and risk of myocardial infarction." Atherosclerosis 395 (August 2024): 118027. http://dx.doi.org/10.1016/j.atherosclerosis.2024.118027.

Full text

APA, Harvard, Vancouver, ISO, and other styles

38

Burnett, John R., Amanda J. Hooper, and Robert A. Hegele. "Remnant Cholesterol and Atherosclerotic Cardiovascular Disease Risk." Journal of the American College of Cardiology 76, no. 23 (2020): 2736–39. http://dx.doi.org/10.1016/j.jacc.2020.10.029.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

Shapiro, Michael D. "The Importance of Remnant Cholesterol in PAD." Journal of the American College of Cardiology 85, no. 12 (2025): 1369–71. https://doi.org/10.1016/j.jacc.2025.01.027.

Full text

APA, Harvard, Vancouver, ISO, and other styles

40

Balling, Mie, Shoaib Afzal, Anette Varbo, Børge G. Nordestgaard, and Anne Langsted. "Remnant Cholesterol: Quantification, Concentrations by Sex and Age, and Risk of Ischemic Heart Disease." Clinical Chemistry, December 26, 2024. https://doi.org/10.1093/clinchem/hvae217.

Full text

Abstract:

Abstract Background Observational and genetic causal studies have shown an association between high concentrations of remnant cholesterol and increased risk of ischemic heart disease. However, findings from randomized intervention trials that reduced plasma triglycerides, a surrogate marker of remnant cholesterol, have been conflicting. The exact mechanisms by which remnant cholesterol contributes to atherosclerosis and, ultimately, ischemic heart disease remain incompletely understood. Additionally, insight on sex and age differences and the importance of measurement differences of remnant ch

APA, Harvard, Vancouver, ISO, and other styles

41

Varbo, Anette, and Børge G. Nordestgaard. "Directly measured vs. calculated remnant cholesterol identifies additional overlooked individuals in the general population at higher risk of myocardial infarction." European Heart Journal, May 23, 2021. http://dx.doi.org/10.1093/eurheartj/ehab293.

Full text

Abstract:

Abstract Aims We tested the hypothesis that high directly measured remnant cholesterol is associated with increased risk of ischaemic heart disease (IHD) and myocardial infarction (MI) in the general population. We also explored whether directly measured vs. calculated remnant cholesterol is superior in identifying individuals at increased risk. Methods and results Overall, 16 207 individuals from the Copenhagen General Population Study with both directly measured and calculated remnant cholesterol, both representing cholesterol content in triglyceride-rich lipoproteins, were followed up for 1

APA, Harvard, Vancouver, ISO, and other styles

42

Wadstrom, B. N., K. M. Pedersen, A. B. Wulff, and B. G. Nordestgaard. "Remnant cholesterol, not LDL cholesterol, explains peripheral artery disease risk conferred by apolipoprotein B: a cohort study." European Heart Journal 45, Supplement_1 (2024). http://dx.doi.org/10.1093/eurheartj/ehae666.2272.

Full text

Abstract:

Abstract Background Elevated apolipoprotein B (apoB)-containing lipoproteins (=remnants + low-density lipoproteins [LDL]) are a major risk factor for atherosclerotic cardiovascular disease, including peripheral artery disease (PAD) and myocardial infarction. We tested the hypothesis that remnants and LDL both explain part of the increased risk of PAD conferred by elevated apoB-containing lipoproteins. For comparison, we also studied risk of chronic limb-threatening ischemia and myocardial infarction. Methods ApoB, remnant cholesterol, and LDL cholesterol were measured in 93,461 individuals wit

APA, Harvard, Vancouver, ISO, and other styles

43

Wadström, Benjamin N., Kasper M. Pedersen, Anders B. Wulff, and Børge G. Nordestgaard. "Remnant Cholesterol, Not LDL Cholesterol, Explains Peripheral Artery Disease Risk Conferred by apoB: A Cohort Study." Arteriosclerosis, Thrombosis, and Vascular Biology, March 21, 2024. http://dx.doi.org/10.1161/atvbaha.123.320175.

Full text

Abstract:

BACKGROUND: Elevated apoB-containing lipoproteins (=remnants+LDLs [low-density lipoproteins]) are a major risk factor for atherosclerotic cardiovascular disease, including peripheral artery disease (PAD) and myocardial infarction. We tested the hypothesis that remnants and LDL both explain part of the increased risk of PAD conferred by elevated apoB-containing lipoproteins. For comparison, we also studied the risk of chronic limb-threatening ischemia and myocardial infarction. METHODS: apoB, remnant cholesterol, and LDL cholesterol were measured in 93 461 individuals without statin use at base

APA, Harvard, Vancouver, ISO, and other styles

44

Bruemmer, Dennis, and Leslie Cho. "Remnant Cholesterol." Circulation: Cardiovascular Imaging 14, no. 4 (2021). http://dx.doi.org/10.1161/circimaging.121.012615.

Full text

APA, Harvard, Vancouver, ISO, and other styles

45

Nilsson Wadstrom, Benjamin, Carolina Borges, Anders Wulff, George Smith, Eleanor Sanderson, and Borge Nordestgaard. "Abstract 4142669: Elevated remnant cholesterol, LDL cholesterol, and risk of peripheral artery disease: a Mendelian randomization study." Circulation 150, Suppl_1 (2024). http://dx.doi.org/10.1161/circ.150.suppl_1.4142669.

Full text

Abstract:

Background: Elevated remnant cholesterol and low-density lipoprotein (LDL) cholesterol both increase risk of coronary artery disease (CAD), but it is not known if the same is true for peripheral artery disease (PAD). Hypothesis: We tested the hypothesis that elevated remnant cholesterol and LDL cholesterol, each independent of the other, have causal effects on risk of PAD. Methods: We constructed genetic scores from variants near genes known to directly affect levels of remnant cholesterol and LDL cholesterol, identified through a genome-wide association study of individuals in the UK Biobank.

APA, Harvard, Vancouver, ISO, and other styles

46

Björnson, Elias, Martin Adiels, Marja-Riitta Taskinen, et al. "Triglyceride-rich lipoprotein remnants, low-density lipoproteins, and risk of coronary heart disease: a UK Biobank study." European Heart Journal, June 26, 2023. http://dx.doi.org/10.1093/eurheartj/ehad337.

Full text

Abstract:

Abstract Aims The strength of the relationship of triglyceride-rich lipoproteins (TRL) with risk of coronary heart disease (CHD) compared with low-density lipoprotein (LDL) is yet to be resolved. Methods and results Single-nucleotide polymorphisms (SNPs) associated with TRL/remnant cholesterol (TRL/remnant-C) and LDL cholesterol (LDL-C) were identified in the UK Biobank population. In a multivariable Mendelian randomization analysis, TRL/remnant-C was strongly and independently associated with CHD in a model adjusted for apolipoprotein B (apoB). Likewise, in a multivariable model, TRL/remnant-

APA, Harvard, Vancouver, ISO, and other styles

47

Nordestgaard, A. T., and B. G. Nordestgaard. "Remnant cholesterol lowering in cardiovascular disease risk reduction in statin trials: meta-regression analyses." European Heart Journal 45, Supplement_1 (2024). http://dx.doi.org/10.1093/eurheartj/ehae666.2816.

Full text

Abstract:

Abstract Background Remnant cholesterol is a causal risk factor for cardiovascular disease. Purpose We tested the hypothesis that remnant cholesterol reduction explains part of the cardiovascular disease risk reduction in statin trials. Methods We included statin trials with &gt;1,000 participants and available data on lipid levels. Baseline and follow-up low-density lipoprotein (LDL) and remnant cholesterol levels were extracted. LDL and remnant cholesterol reductions were differences between intervention and reference groups at year one. Risk ratios for any statin use and per 1 mmol/L (3

APA, Harvard, Vancouver, ISO, and other styles

48

Wulff, Anders B., and Børge G. Nordestgaard. "Genetics of remnant cholesterol." Current Opinion in Lipidology, April 23, 2025. https://doi.org/10.1097/mol.0000000000000991.

Full text

Abstract:

Purpose of review Remnant cholesterol is receiving increasing attention as a target to reduce residual atherosclerotic cardiovascular disease (ASCVD) risk in individuals already treated with statins. New therapeutic options as antisense oligonucleotides, small interfering RNA, and monoclonal antibodies allow specific targeting of genes and proteins to counter pathological pathways promoted by these genes. Identifying genetic determinants of remnant cholesterol and relating these to risk of ASCVD is thus an appealing path to identifying and evaluating new and existing drug targets. Recent findi

APA, Harvard, Vancouver, ISO, and other styles

49

Wu, Zhiyuan, Haiping Zhang, Yi Xu, et al. "Low Remnant Cholesterol and In‐Hospital Bleeding Risk After Ischemic Stroke or Transient Ischemic Attack." Journal of the American Heart Association, July 9, 2024. http://dx.doi.org/10.1161/jaha.124.034307.

Full text

Abstract:

Background Bleeding risk brought by intensive lipid‐lowering therapy and low low‐density lipoprotein cholesterol is concerning, while evidence regarding the relationship between remnant cholesterol and bleeding is frightening. This study aimed to investigate the association between remnant cholesterol at admission and an in‐hospital bleeding event after acute ischemic stroke or transient ischemic attack (TIA). Methods and Results A total of 3222 eligible patients admitted to Shanghai Huashan Hospital between 2015 and 2021 with complete lipid data were analyzed. Patients were classified into lo

APA, Harvard, Vancouver, ISO, and other styles

50

Qian, Sifan, Shoujiang You, Yaming Sun, et al. "Remnant Cholesterol and Common Carotid Artery Intima-Media Thickness in Patients With Ischemic Stroke." Circulation: Cardiovascular Imaging 14, no. 4 (2021). http://dx.doi.org/10.1161/circimaging.120.010953.

Full text

Abstract:

Background: Remnant cholesterol makes great contribution to residual risk of cardiovascular disease, but population-based evidence on the relationship between remnant cholesterol and atherosclerosis is rare. Common carotid artery intima-media thickness (cIMT) is an imaging marker of subclinical atherosclerosis. We aimed to explore the association between remnant cholesterol levels and cIMT in patients with ischemic stroke. Methods: One thousand four hundred ninety-six ischemic stroke patients with baseline serum lipids and carotid artery imaging data were included in this analysis. Fasting rem

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!