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Journal articles on the topic 'Renal function tests (RFT)'

Author: Grafiati

Published: 5 June 2025

Last updated: 2 August 2025

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1

Navanil, Roy, and Ahsan Lodhi Rashid. "Evaluation of Liver Function Test and Renal Function Test in Pre-eclampsia: A Case Control Study." PJSR 12, no. 1 (2019): 18–23. https://doi.org/10.5281/zenodo.8245427.

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Pre-eclampsia is a multisystem disorder, which occurs only in pregnant women during the second and third  trimesters  of  pregnancy  and  is  associated  with  raised  blood  pressure  and  proteinuria.  Liver  function  Test  (LFT)  abnormalities occur in 3% of the pregnancies and probably the lesion that causes elevated serum liver enzymes. With  severe renal involvement, glomerular filtration may be impaired and the plasma creatinine concentration begins to rise.  This study was conducted to compa

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Dipika, Sathvara, Patel Digisha, and Kubavat Pruthviraj. "A Study on Renal Function Tests and its Correlation with Blood Glucose (FBS and PPBS) in Newly Diagnosed Type-2 Diabetes Mellitus." International Journal of Pharmaceutical and Clinical Research 16, no. 6 (2024): 1031–34. https://doi.org/10.5281/zenodo.12738883.

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<strong>Background and Objectives:</strong> Diabetes mellitus is a metabolic disorder characterized by increased blood sugar levels. It is of two types. Type two is very common, due to deficiency in secretion of insulin. That eventually affects derangement of carbohydrate, protein and lipid metabolism. On long standing, this metabolic derangement will affect vital organs like liver, kidney, brain etc. To study correlation analysis that determine strength and direction of relationship between indicator of DM (FBS and PPBS) and RFT (serum urea and serum creatinine) in Indian population.&nbs

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Nath, Snehasish, Suniti Kumar Hajra, and Debayan Chowdhury. "Evaluation of hepatic and renal functional changes in patients undergoing laparoscopic cholecystectomy." Asian Journal of Medical Sciences 15, no. 4 (2024): 234–38. http://dx.doi.org/10.3126/ajms.v15i4.61510.

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Background: In this era of laparoscopic surgery, with the use of carbon dioxide insufflation in creating pneumoperitoneum for ease of trocar insertion and visualization of anatomy, it comes certain systemic changes in the patient due to the compression effect of the gas as well as resorption of it through peritoneum. Aims and Objectives: The aim of the study was to assess baseline standards of hepatic and renal functional status in pre-operative patients in comparison with post-operative patients undergoing laparoscopic cholecystectomy (LC). Materials and Methods: Cases were chosen among the p

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Kutlusoy, Sevgi, Erdinç Koca, and Ahmet Aydın. "Renal dysfunction due to surgical stress and its effects on survival in patients aged 90 and over." Journal of Surgery and Medicine 7, no. 8 (2023): 486–90. http://dx.doi.org/10.28982/josam.7847.

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Background/Aim: Published studies of surgical outcomes in patients aged 90 years and older have mostly focused on specific surgeries such as hip fractures. Unlike previous reports, our study includes all surgical procedures in patient groups aged 90 and over for eight years in our hospital. We aim to be able to predict the responses of an older adult’s kidney due to surgical stress by using the values of plasma urea and creatine, which are preoperative and postoperative routine laboratory parameters, and to predict its effect on mortality. Methods: Our study was conducted as a retrospective co

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Ebar, Mohamed Hassan Osman, and Ali Bile Farah Hassan. "Evaluation of Renal Function Status in Type II Diabetic Patients at Khartoum State, Sudan." Journal of Drug Delivery and Therapeutics 12, no. 6-S (2022): 4–6. http://dx.doi.org/10.22270/jddt.v12i6-s.5830.

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Background: ‏ Type II Diabetes mellitus is the most common type of DM which constitute about 85-95% of all Diabetes mellitus cases. Diabetic nephropathy is the kidney disease that occurs as a result of diabetes complication. The aim of this study was to evaluate the renal function status in Sudanese type 2 diabetic patients at Khartoum state, Sudan. Materials and Method: This study was analytical case control hospital-based study conducted at International University of Africa Hospital, Khartoum state, Sudan, during the period from February to May 2022. Type II diabetic patients who atte

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Shah, Shrenik J., Chirag Davara, Abhishek Jha, Kapil Kachhadiya, and Rushi Mistry. "Percutaneous Nephrolithotomy 500 Cases in High-Risk and Altered Renal Function Test: Our Experience at Tertiary Care Centre." Urology and Andrology – Open Journal 7, no. 1 (2024): 7–11. http://dx.doi.org/10.17140/uaoj-7-144.

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Introduction The study aims to evaluate the results of percutaneous nephrolithotomy (PCNL) in high-risk patients and patients with altered renal function tests (RFT) and complications in the management of renal stones in our hospital. Methods We retrospectively analyzed the outcomes of 500 patients who underwent PCNL between September 2020 and September 2023. We have analyzed data regarding patient details, investigations, PCNL puncture site, operative duration, number of punctures, stone-free rates (SFRs), duration of hospital stay, and complications. Results Out of 500 patients, 384 (76.87%)

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Al-Tameemi, Hamid K., Noor Ibrahim, Dina A. A. Abdullah, and Noor Nayyef Oddah. "Assessment of parathyroid hormone, vitamin D3, calcium, phosphate, and RFT in patients with chronic renal failure: A three-year follow-up study." Polski Merkuriusz Lekarski 53, no. 1 (2025): 40–46. https://doi.org/10.36740/merkur202501106.

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Aim: This study aimed to evaluate the serum levels of key biomarkers, including parathyroid hormone (PTH), vitamin D3, calcium, phosphate, and renal function tests (RFTS), in patients with chronic renal failure over three years. Materials and Methods: A cohort of 83 patients with chronic renal failure and 70 healthy controls were followed, with data collected at one, two, and three years. Results: Significant differences were observed in the levels of creatinine, urea, phosphate, calcium, vitamin D, and parathyroid hormone between patients and controls. the study found a progressive increase i

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Khalid, Laiba, and Akash Kumar. "Audit of Renal Function Monitoring and Indications in Patients Prescribed Memantine at Ribchester Centre: A Review of Compliance With Pre-Prescription Guidelines." BJPsych Open 11, S1 (2025): S250. https://doi.org/10.1192/bjo.2025.10618.

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Aims: To assess whether renal function tests are appropriately reviewed prior to the prescription of memantine, in accordance with NICE clinical guidelines, ensuring the safety and effectiveness of medication.To assess if memantine is prescribed according to the indications listed in NICE guidelines.Methods: This retrospective audit reviewed patients with a diagnosis of dementia, seen at old age psychiatry outpatient clinic Bury from 1 August to 31 October 2024.The review focused on patients starting memantine during this period, assessing whether renal function was evaluated prior to initiati

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Sharma, Pradeep K., Vikas Aggarwal, Naresh Sapariya, Shekhar Baweja, Rupesh Nagori, and M. K. Chabbra. "Renal profile of COVID-19 infected patients admitted in a tertiary care hospital in Western Rajasthan." International Surgery Journal 7, no. 7 (2020): 2332. http://dx.doi.org/10.18203/2349-2902.isj20202845.

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Background: A recent cluster of pneumonia cases all over the world including India, is caused by a novel beta coronavirus, the 2019 novel coronavirus (2019-nCoV). The objective of this study was to observe the effect on renal profiles at admission of these COVID-19 infected patients.Methods: All the patients were admitted to Dr. S. N. Medical College and Hospital, Jodhpur, a tertiary care hospital of Western Rajasthan and were tested for COVID-19 by real time reverse transcription polymerase chain reaction assay of 2019-nCoVRNA. All data in relation to patients including blood renal profile we

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Bansal, Ankush, Tejinder Sikri, and Satya Bhushan Nayyar. "Evaluation of Renal Microvascular Damage by Measuring Microalbuminuria in Non-Alcoholic Fatty Liver Disease – A Study from Punjab, India." Journal of Evidence Based Medicine and Healthcare 8, no. 28 (2021): 2497–502. http://dx.doi.org/10.18410/jebmh/2021/462.

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BACKGROUND Non-alcoholic fatty liver disease (NAFLD) is a clinicopathological syndrome characterized by obesity, dyslipidaemia, insulin resistance and diabetes mellitus (DM). NAFLD represents another component of metabolic syndrome. NAFLD and metabolic syndrome are associated with increased risk of atherosclerosis. METHODS In the present comparative cross-sectional study, 100 cases with incidental NAFLD and 100 healthy controls were subjected to detailed history, physical examination including body-mass index (BMI) and biochemical investigations including renal function tests (RFT), lipid prof

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Ram Kiran, K. S., Visharad Trivedi, Venuthurupalli S. P. Rajesh, Manisha Sharma, Maruti Haranal, and Himani Pandya. "Role of Prophylactic N-Acetylcysteine Supplementation on Postoperative Outcomes in Patients Undergoing Elective Double-Valve Replacement (Aortic and Mitral Valve)." Annals of Cardiac Anaesthesia 27, no. 4 (2024): 324–29. http://dx.doi.org/10.4103/aca.aca_66_24.

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ABSTRACT Aims and Objectives: The incidence of postoperative liver dysfunction is high in patients undergoing double-valve replacement – mitral and aortic valve replacement (DVR). This study aims to evaluate N-acetylcysteine’s free radical scavenging property (NAC) to prevent postoperative liver dysfunction in these patients, thus affecting overall clinical outcomes. Methods: A single-center, prospective, randomized, double-blinded interventional study of 60 patients divided into two groups of 30 each. Group N received prophylactic intravenous NAC, and Group C received volume-matched 5% dextro

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Shakil, Muhammad, Abdul Majid Mujahid, Farrukh Mahmood, Muhammad Asif, and Muhammad Ilyas. "Analysis of Ultrasound as a Predictor of Renal Impairment in Patients with HCV Infection." Pakistan Journal of Medical and Health Sciences 16, no. 1 (2022): 782–85. http://dx.doi.org/10.53350/pjmhs22161782.

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Background: Renal arterial waveform analysis done via renal Duplex Doppler Ultrasound gives a safe, trustworthy, and real time assessment of renal hemodynamics without any delay and ambiguity as it removes various components that make estimation of renal function problematic. Objective: To evaluate the clinical validity of RI and to identify the relationship between RI and RFT’s for evaluation of renal function in patient. Analytical cross sectional examination was done at DHQ teaching hospital Sargodha from 2020 to 2021. The it had 158 hepatitis C positive patients and 79 healthy volunteers f

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Volkan, Gelen, and Şengül Emin. "Protective effects of resveratrol on kidney function tests and renal histopathology in carbon tetrachloride-induced renal toxicity in rats." World Journal of Advanced Research and Reviews 10, no. 1 (2021): 156–61. https://doi.org/10.5281/zenodo.4733585.

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In this study, it was aimed to investigate the protective effect of Resveratrol, which has a strong antioxidant effect on kidney tissues of rats experimentally induced with carbon tetrachloride with nephrotoxicity, by kidney function tests and histopathology. For this purpose, 32 male Wistar Albino rats were used. The subjects were randomly selected, 1<sup>st</sup> group control, 2<sup>nd</sup> group CCl4, 3<sup>rd</sup> group Resveratrol. The 4<sup>th</sup> group was divided into 4 groups as CCl4 + Resveratrol. At the end of the experiment, animals were sacrificed under an

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Berkovitch, Matitiahu, Roni Tsadik, Eran Kozer, and Ibrahim Abu-Kishk. "The Effect of Hyperbaric Oxygen Therapy on Kidneys in a Rat Model." Scientific World Journal 2014 (2014): 1–4. http://dx.doi.org/10.1155/2014/105069.

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Background. Hyperbaric oxygen therapy (HBOT) is used for treating various medical conditions. As far as known yet, HBOT is safe with few major side effects that are easy to avoid using a proper protocol. Renal tubular damage was observed in rats exposed to HBOT in a preliminary study conducted in our institution.Aim. We aim to assess whether HBOT causes renal damage and, if so, whether this is dose dependent.Methods. Thirty-one rats were randomly assigned to three groups. The first group received 10-days HBOT, 100% oxygen at a pressure of 2 atmospheres absolute (2 ATA) for 60 minutes/day, the

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Shrestha, Sreska, and Priyatam Khadka. "Neglected Case of Human Balantidiasis: Presumed as Antibiotic-Associated Diarrhoea." Case Reports in Infectious Diseases 2022 (June 13, 2022): 1–4. http://dx.doi.org/10.1155/2022/6013151.

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Background. Balantidiasis, due to its rare human incidence and nonspecific clinical presentations often neglected from the diagnosis considerations; however, a potent pathogen. Herein, we report a case of neglected balantidiasis presumed as antibiotic-associated diarrhoea. Case Presentation. A 27-year-old policeman presented in Sindhuli Hospital, with a chief complaint of epigastric pain, nausea, decreased appetite for several days, and loose stools (3-4 episodes per day). Previously, he was under antibiotic therapy (amoxycillin) for tonsillitis. The health post clinician made a presumptive di

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Bahuguna, Rashi, Devesh Joshi, and Madhulata Rana. "A Case Report on Allergic Reaction to Pantoprazole." International Journal of Science and Healthcare Research 6, no. 4 (2021): 82–86. http://dx.doi.org/10.52403/ijshr.20211013.

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Pantoprazole is a proton pump inhibitor and acts by blocking the gastric pump H+, K-ATPase to inhibit gastric acid secretion. Hypersensitivity reactions due to pantoprazole can be both immediate and delayed hypersensitivity reactions but sometimes it can be a life-threatening anaphylactic reaction. A 64-year female was admitted to the private ward of Shri Mahant Indiresh hospital with chief complaints of 6-7 episodes of vomiting and abdominal pain. Various laboratory tests were performed and the diagnosis was given. After the administration of Injection pantoprazole 40 mg patient developed ras

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HA, Krishnamurthy, Bhangari VS, and Sandesh L. "The significance of ratio between serum triglycerides and HDL cholesterol as a common man’s bio marker of insulin resistance in type 2 diabetes mellitus: A cross sectional comparative study." Journal of Medical and Scientific Research 11, no. 3 (2023): 210–14. http://dx.doi.org/10.17727/jmsr.2023/11-39.

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Introduction: Insulin resistance is the most common abnormality associated with obesity, as a major pathophysiological factor in the development and progression of cardiovascular diseases and diabetes mellitus. This study is undertaken to know the significance of ratio of triglycerides (TG) to high-density lipoprotein (HDL) cholesterol as a serum biomarker in assessing the insulin resistance compared to homeostatic model assessment of insulin resistance (HOMA-IR) in type 2 diabetes mellitus (DM) subjects. Materials and methods: This was a cross sectional comparative study done at Mysore Medica

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Nirwan, Dileep Singh, R. K. Vyas, and Sunil Jain. "Comparative study of serum urea, creatinine and C-reactive protein level in chronic kidney disease patients with healthy subjects." International Journal of Research in Medical Sciences 5, no. 4 (2017): 1480. http://dx.doi.org/10.18203/2320-6012.ijrms20171250.

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Background: Chronic diseases are a leading cause of morbidity and mortality in India. Globally, chronic kidney disease is the 12th cause of death and the 17th cause of disability, respectively. CKD is defined as kidney damage or glomerular filtration rate (GFR) <60 mL/min/1.73 m2 for 3 months or more, irrespective of cause. The present study aimed to find out correlation between serum urea, creatinine and C-reactive protein (CRP) level among patients suffering from chronic kidney disease in an urban based tertiary care hospital in Bikaner, western Rajasthan, India.Methods: This study was co

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Edbor, Anjali, and Himanshu Dua. "Renal functions in term neonates with weight loss of more than 10% in early neonatal period - A cross sectional study." Panacea Journal of Medical Sciences 12, no. 1 (2022): 82–85. http://dx.doi.org/10.18231/j.pjms.2022.016.

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Normally neonates lose 5-7% of their birth weight in the first week of life. Inadequate breastfeeding resulting from different factors may result in dehydration and excessive weight loss. Hypernatremic dehydration leading to acute kidney injury (AKI) is a well-known complication of lactational insufficiency in exclusively breast-fed babies progresses from pre-renal to intrinsic renal injury, if persistent. Acute kidney injury (AKI) is a complex disorder which has a clinical manifestations ranging from mild dysfunction to complete anuric kidney failure.To evaluate renal function tests (RFT) in

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Hassan, Sherif S., Ayman Rizk, Charity Thomann, Ahmed Motawie, Shereen Abdelfattah, and Zulfiqar Ahmad. "Preconditioning with atorvastatin against renal ischemia–reperfusion injury in nondiabetic versus diabetic rats." Canadian Journal of Physiology and Pharmacology 97, no. 1 (2019): 1–14. http://dx.doi.org/10.1139/cjpp-2018-0228.

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Acute renal failure complicates renal ischemia–reperfusion (I/R) owing to reactive oxygen species production. Atorvastatin (ATO) has anti-inflammatory and antioxidant properties. The current study investigated whether ATO alleviated damage induced by renal I/R injury in nondiabetic versus diabetic rat models. Thirty-six rats were equally divided into 6 groups: group A1 (nondiabetic sham), group A2 (nondiabetic I/R), group A3 (nondiabetic ATO + I/R), group B1 (diabetic sham), group B2 (diabetic I/R), and group B3 (diabetic ATO + I/R). All groups experienced 45 min of bilateral renal ischemia fo

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Shanti, Snehlata, Kumari Sadhna, and Rani Choudhary Raj. "Analysis of Role of Single Dose Magnesium Sulphate in Cases of Severe Pre-Eclampsia in A Tertiary Care Centre." International Journal of Toxicological and Pharmacological Research 13, no. 8 (2023): 163–65. https://doi.org/10.5281/zenodo.11098803.

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<strong>Background:</strong> Preeclampsia is a pregnancy specific multi organ disease process characterized by de novo development of hypertension and proteinuria after 20 weeks of gestation. It complicates 2-8 % of pregnancies. <strong>Aims and Objective: </strong>To study the effect of single dose magnesium sulphate in cases of severe preeclampsia to reduce the incidence of seizures. The ultimate aim is to reduce maternal mortality and morbidity and improve perinatal outcome. <strong>Material and Methods:</strong> In this study total 100 patients with severe preeclam

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ALSuwayfee, Khaleel I. "The strategy of paracetamol (acetaminophen) use in closing patent ductus arteriosus in premature neonates." Journal of the Faculty of Medicine Baghdad 58, no. 3 (2016): 255–63. http://dx.doi.org/10.32007/jfacmedbagdad.583260.

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Background: Patent ductus arteriosus (PDA) is a common problem in premature neonates which can be closed pharmacologically using nonsteroidal anti-inflammatory drugs (NSAIDs) with many side effects. Recently paracetamol is used in this field when these drugs can not be used like in cases of gastrointestinal (G.I.T) bleeding or perforation, or if the patient doesn’t show response to the NSAIDs and it seems to be of good safety. To the best knowledge this is the first paper that describes in details the strategy of using paracetamol in closing PDA in premature neonates and gives recommendations

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Munir, Atif, Sehar Gulzar, Ather Afzal, et al. "Prevalence of Diabetic Nephropathy among Patients of Type 2 Diabetes at Tertiary Care Hospital Lahore." Journal of Health and Rehabilitation Research 4, no. 2 (2024): 1607–11. http://dx.doi.org/10.61919/jhrr.v4i2.1108.

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Background: Diabetic nephropathy is a significant complication of Type 2 Diabetes Mellitus, often leading to chronic kidney disease (CKD) and potentially progressing to End-Stage Renal Disease (ESRD). Approximately 90% of individuals with diabetes and hypertension may develop ESRD in the later stages of the disease. Objective: The study aimed to determine the prevalence of diabetic nephropathy among patients with type 2 diabetes at a tertiary care hospital in Lahore. Methods: This retrospective study included 100 reports from the chemical pathology and microbiology laboratory at Fatima Memoria

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Saleem, Uzma, Liaqat Hussain, Faiza shahid, Fareeha Anwar, Zunera Chauhdary, and Aimen Zafar. "Pharmacological Potential of the Standardized Methanolic Extract of Prunus armeniaca L. in the Haloperidol-Induced Parkinsonism Rat Model." Evidence-Based Complementary and Alternative Medicine 2022 (September 29, 2022): 1–15. http://dx.doi.org/10.1155/2022/3697522.

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Parkinson’s disease (PD) is a complex, age-related neurodegenerative disease that causes neuronal loss and dysfunction over time. An imbalance of redox potential of oxidative stress in the cell causes neurodegenerative diseases and dysfunction of neurons. Plants are a rich source of bioactive substances that attenuate oxidative stress in a variety of neurological disorders. The aim of the present study was to evaluate the Prunus armeniaca L. methanolic extract (PAME) for anti-Parkinson activity in rats. PD was induced with haloperidol (1 mg/kg, IP). The PAME was administered orally at 100, 300

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Nain, Parminder, Narendra Nayak, Mary C. Maj, et al. "Efficacy of Lanthanum Carbonate and Sevelamer Carbonate as Phosphate Binders in Chronic Kidney Disease—A Comparative Clinical Study." Pharmacy 11, no. 1 (2023): 27. http://dx.doi.org/10.3390/pharmacy11010027.

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(1) Background: Hyperphosphatemia is correlated with an increased rate of mortality and morbidity due to cardiovascular diseases in chronic kidney disease (CKD) patients. It can be improved by restricting dietary intake of phosphate and oral phosphate binders, such as lanthanum carbonate and sevelamer carbonate. (2) Objective: To evaluate the clinical efficacy of sevelamer carbonate in comparison to lanthanum carbonate as phosphate binders for the treatment of hyperphosphatemia in CKD patients. (3) Methods: A randomized control comparative clinical study was conducted for one year on 150 CKD p

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Warraich, Neelofar Yousaf, Amtul Hafeez, Wardah Siddique, Fouzia Parveen, Shahnaz Fatima, and Nazia Rashid. "EFFECT OF CITRULLUS LANATUS SEEDS (ETHANOLIC EXTRACT) ON NORMAL RENAL FUNCTIONS AND SERUM ELECTROLYTES OF ALBINO RATS." Journal of Akhtar Saeed Medical & Dental College 01, no. 02 (2019): 64–68. https://doi.org/10.51127/jamdcv01i02oa05.

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Objectives:To evaluate the effect of Citrullus lanatus seeds on normal renal functions and serum electrolytes for the improvement of kidney health in order to perform its functions in normal and stressful conditions.Methods:The studywas conducted at the Pharmacology Department, KEMU, Lahore and UVAS, Lahore in 2017.It was a randomized controlled trial (RCT). A sample size of 16 healthy albino wistarrats was taken. Rats were divided into two equal groups with 8numberof rats in each group and kept separately in metabolic cages. Group A was normal control group and given normal saline once a day

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Wong, Tsz Chun Bryan, Serene JL Lam, Ka Man Cheung, et al. "AI blood signature in common blood tests for detection of gastric cancer in a cohort of 190,000 individuals." Journal of Clinical Oncology 41, no. 16_suppl (2023): 1500. http://dx.doi.org/10.1200/jco.2023.41.16_suppl.1500.

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1500 Background: Gastric cancer is the fourth leading cause of cancer death worldwide. Lack of symptoms in the early stage of disease leads to delayed presentation and low overall survival rate. Early detection is key, but there is not yet an established test for non-invasive gastric cancer screening. Routine blood test panels, including complete blood count, liver function, renal function and clotting profiles, could be potentially useful in reflecting bodily processes related to cancer. Current literature and territory-wide statistical data analyses from Hong Kong have shown these subtle cha

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Al-Lami, Makarim Q. "Effect of Green Lean Body Capsules on Body Weight, Lipid Profile, and Renal Physiology and Histology in Albino Rats." Journal of the Faculty of Medicine Baghdad 56, no. 4 (2015): 431–35. http://dx.doi.org/10.32007/jfacmedbagdad.564562.

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Background: Many anti-obesity medicines have been increased in recent years to solve the problem of obesity; among these medicines are Green Lean Body Capsules (GLBCs) which contain green plants and fruits extract.Objective: This study was designed to evaluate the effects of daily oral consumption of GLBCs on level of serum lipids, renal function tests, and the histological structure of the kidney in albino rats.Materials and Methods: Twenty adult albino male rats weighing 240-260 g were divided into 2 equal groups: control group and GLBCs-treated group. During the 4-weeks treatment, each rat

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Shalini, Ranjan, Reddy Chaitanya, Doshi Aditya, Gupta Eesha, Gehlot Gaurav, and Gunderwala Fatema. "Comparison of Outcomes of Selective Treatment Modalities in Chronic Kidney Disease Patients Admitted in a Tertiary Care Hospital in Vadodara: A Retrospective Study." International Journal of Pharmaceutical and Clinical Research 15, no. 11 (2023): 98–104. https://doi.org/10.5281/zenodo.11213387.

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<strong>Background:</strong> Due to the rising incidence of diabetes mellitus, hypertension, other non-communicable diseases, and the aging of the population, chronic kidney disease (CKD), considered a severe ailment, is now at epidemic levels. <strong>Aims & Objectives:</strong> This study is aimed to fill the dearth in literature in a local hospital in a developing country like India, where CKD is highly prevalent and needs a quicker, efficacious and standard interventional approach. Study Objectives were centered on comparison and narrowing of the single best outcome for

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Gul, Afnan, and Muhammad Bahadur Baloch. "Protective Effect of Commercial Green Tea on Ibuprofen Induced Changes in Renal Function Tests of Adult Rats." Journal of Shalamar Medical & Dental College - JSHMDC 2, no. 1 (2021): 45–49. http://dx.doi.org/10.53685/jshmdc.v2i1.15.

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Background: Nephrotoxicity of ibuprofen is a growing international public health problem in the wake of excessive use of the drug for the treatment of a broad spectrum of diseases in both adults and pediatric patients. Objectives: To present an overview of the protective effect of the green tea on ibuprofen-induced changes in the biochemical markers of the adult rat kidneys. Methods: It is an experimental study conducted in the department of Anatomy, Army Medical College Rawalpindi. The investigation was led on 30 male and non-pregnant female Sprague Dawley rodents of 9-11 weeks old enough and

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Schlüter, Torsten, Rita Grimm, Antje Steinbach, Gerd Lorenz, Rainer Rettig, and Olaf Grisk. "Neonatal sympathectomy reduces NADPH oxidase activity and vascular resistance in spontaneously hypertensive rat kidneys." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 291, no. 2 (2006): R391—R399. http://dx.doi.org/10.1152/ajpregu.00029.2006.

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Neonatal sympathectomy reduces arterial pressure in spontaneously hypertensive rats (SHR). In SHR transplanted with a kidney from sympathectomized SHR, arterial pressure was lower and less Na+ sensitive than in SHR transplanted with a kidney from hydralazine-treated SHR. This study was performed to identify underlying renal mechanisms. Tests for differential renal mRNA expression of nine a priori selected genes revealed robust differences for renal medullary expression of the NADPH oxidase subunit p47phox. Therefore, we investigated the effects of neonatal sympathectomy on renal mRNA expressio

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Bande, Uday Subhash, Kalinga Bommanakatte Eranaik, Manjunath Shivalingappa Hiremani, Basawantrao Kailash Patil, and Sushma Shankaragouda Biradar. "The Study of Serum Calcium to Magnesium Ratio in Patients with Acute Coronary Syndrome in a Tertiary Hospital, Hubli, Karnataka." Journal of Evidence Based Medicine and Healthcare 8, no. 41 (2021): 3553–58. http://dx.doi.org/10.18410/jebmh/2021/644.

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BACKGROUND Cardiovascular diseases are one of the leading causes of morbidity and mortality worldwide. High Ca levels and low Mg levels are associated with increased cardiovascular risk in the general population.1 The balance between Ca and Mg seems to play an important role in homeostasis since Mg is considered as physiologic antagonist of Ca.2 Hence Ca/Mg ratio was considered to study its association with acute coronary syndrome (ACS). METHODS This is a case control study conducted in Karnataka Institute of Medical Sciences, Hubli over a period of 2 years, February 2019 to December 2020. 200

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Alhaidan, Taghreed, Abdullah R. Alzahrani, Abdulwahab Alamri, et al. "Reported Cases of Alcohol Consumption and Poisoning for the Years 2015 to 2022 in Hail, Saudi Arabia." International Journal of Environmental Research and Public Health 19, no. 22 (2022): 15291. http://dx.doi.org/10.3390/ijerph192215291.

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This study aimed to determine the pattern of alcohol consumption and its poisoning among the Saudi population in the city of Hail, KSA. Data from a retrospective cohort were collected qualitatively at King Khalid Hospital (KKH) and Hail General Hospital (HGH), covering 550 participants from 2015 to 2022. Two groups were formed comprising patients admitted to the emergency room (ER) and community members; their ages ranged from 19 to 75 years. Group 1 contained 400 participants, of which 250 were patients (244 males, six females) who came to the (ER) with a suspected alcohol overdose or poisoni

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Omar, Mouna, Abdunnabi Rayes, Nagat Alkmishi, et al. "Assessment of thyroid function and biochemical markers among COVID-19 Libyan patients." Journal of Microbiology and Infectious Diseases 13, no. 3 (2023): 128. http://dx.doi.org/10.5455/jmid.2023.v13.i3.5.

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Background: There is a scarcity of data on thyroid function abnormality in coronavirus disease 2019 (COVID-19) outpatients in the world literature since previous studies were done on admitted patients. Aim: The objective of this study was to assess thyroid function tests (TFT) in Libyan outpatients with COVID-19 as well as the possible association between them and some routine hematological, inflammatory and biochemical markers. Methods: Laboratory results were retrospectively reviewed for a total number of 246 patients, where 214 patients with laboratory-confirmed COVID-19 and 32 non-COVID-19

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Azevedo, Italo Medeiros, Gabriela Vieira da Silva, Aristela Sinara Varela Constantino de Medeiros, Ariadne Sibelle Varela Constantino de Medeiros Dumaresq de Souza, Rosana Karla Aires de Macêdo, and Aldo Cunha Medeiros. "Tadalafil combined with remote ischemic preconditioning in the prevention of renal ischemia/reperfusion injury." JOURNAL OF SURGICAL AND CLINICAL RESEARCH 9, no. 1 (2018): 11–23. http://dx.doi.org/10.20398/jscr.v9i1.15731.

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PURPOSE: This study aimed to evaluate whether the combination of tadalafil treatment and remote ischemic preconditioning may provide protection against ischemia reperfusion injury (I/R) in kidneys of rats. METHODS: Twenty-four male Wistar rats weighing 280-300g were randomly divided into 3 groups: Group 1 - (control), only right nephrectomy was performed. No treatment with tadalafil. Group II - Left renal ischemia, right nephrectomy, without remote preconditioning, treatment with tadalafil (1.0 mg/kg, oral). Group III - Left renal ischemia, right nephrectomy, with remote preconditioning, treat

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Karan, Saradava, Patel Kinjal, and Solanki Gopi. "Study of Infections among Children with Multitransfused Thalassemia Major." International Journal of Current Pharmaceutical Review and Research 15, no. 10 (2023): 425–28. https://doi.org/10.5281/zenodo.11632320.

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AbstractBackground and Aim: Due to the high annual expense of thalassemia treatment in India, the majority ofthalassemic children receive insufficient blood transfusions and inadequate iron chelation therapy. Infection isthe major cause of morbidity and mortality in thalassemia, so regular screening is required for this disease.Material and Methods: The investigation was carried out in the Pediatrics department of Tertiary care Hospitalof India. The study included 75 patients with thalassemia who were between the ages of 2 and 18 at the time oftheir diagnosis. According to the supplied proform

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Shahzad Alam khan, Faisal Ramzan, Noshad javed, Hamad Arshad, Sadam Hussain, and Muhammad Usman Zaffar. "Frequency of anemia in patients with pulmonary TB presenting at Nishtar Hospital Multan." Medical Journal Of South Punjab 4, no. 01 (2023): 11–20. http://dx.doi.org/10.61581/mjsp.vol04/01/02.

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Objective: The present study aimed to determine the frequency of anemia in patients with pulmonary TB presenting at Nishtar Hospital Multan and its classification as per the severity and morphological characteristics. Methods: This retrospective cross-sectional study was conducted at Nishtar Hospital Multan. A total of 109 TB patients were enrolled and underwent physical and systemic examination. Blood samples were collected to estimate complete blood counts (CBC), liver and renal function tests (LFT; RFT), serum albumin, and C - reactive protein (CRP) levels. Abdominal ultrasound was pe

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Koirala, Sarbottam, Rano Mal Piryani, Akash Shahi, Shristi Bhandari, Sanjay Shah, and Smita Bashyal. "Status of glycemic control and lipid profile in type 2 diabetes mellitus: A descriptive cross-sectional study." Journal of Gandaki Medical College-Nepal 16, no. 2 (2023): 100–104. http://dx.doi.org/10.3126/jgmcn.v16i2.56382.

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Introduction: Dyslipidemia in diabetes mellitus is commonly seen in the form of high total cholesterol (TC), high lowdensity lipoprotein (LDL), high triglyceride (TG) and low high-density lipoprotein (HDL) levels. This study was done to study the association of glycemic control with lipid profile in Type 2 Diabetes Mellitus (T2DM) patients. Methods:This was a cross sectional, observational study conducted from December 2018 to June 2020 at Universal College of Medical Sciences and Teaching Hospital, Bhairahawa. It involved 125 patients of type 2 diabetes mellitus (68 males and 57 females), who

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Bahuguna, Rashi, Devesh Joshi, and Madhulata Rana. "Ciprofloxacin and Metronidazole Allergy- A Case Report." International Journal of Science and Healthcare Research 6, no. 4 (2021): 87–92. http://dx.doi.org/10.52403/ijshr.20211014.

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Fluoroquinolones are well-tolerated antibiotics widely used for treating infections. According to the literature, ciprofloxacin is mostly involved in Drug-induced hypersensitivity reactions. The various reactions that are reported in various case reports due to ciprofloxacin include Steven Johnson syndrome, eczema, erythroderma, maculopapular rashes. Metronidazole is a 5-nitroimidazole compound introduced in 1959 to treat Trichomonas vaginalis infections. Ciprofloxacin and Metronidazole hypersensitivity is not very frequent it is usually well tolerated but allergic reactions to these drugs occ

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Sumit, Mishra, Ranjan Alok, and Mohan Sinha Chandra. "To Determine the Correlation between Cholelithiasis and Body Mass Index (BMI) and Waist-To-Hip Ratio." International Journal of Current Pharmaceutical Review and Research 16, no. 04 (2024): 632–37. https://doi.org/10.5281/zenodo.12801837.

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AbstractAim: To determine the correlation between cholelithiasis and body mass index (BMI) and waist-to-hip ratio.Material and Methods: This research was done in the Department of General surgery, Jawaharlal Nehru MedicalCollege and Hospital, Bhagalpur, Bihar, India for one year, on a sample of 100 individuals who presented withabdominal discomfort and met the specified inclusion criteria. The test group consisted of 50 individuals whowere diagnosed with cholelithiasis, whereas the control group consisted of 50 patients who had abdominaldiscomfort due to causes other than cholelithiasis. The p

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Dong, Fuxing, та Fuyuan Hong. "Exosomes from Umbilical Cord-Originated Mesenchymal Stem Cells (MSCs) Prevent and Treat Diabetic Nephropathy in Rats via Modulating the Wingless-Related Integration Site (Wnt)/β-Catenin Signal Transduction Pathway". Journal of Biomaterials and Tissue Engineering 11, № 7 (2021): 1305–12. http://dx.doi.org/10.1166/jbt.2021.2708.

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For the exosomes secreted by umbilical cord-originated mesenchymal stem cells (so-called hucMSC-exo), they can be applied to treat a variety of clinical diseases as a therapeutic strategy. The Wnt/β-catenin signal pathway has received widespread attention for its capability to modulate multiple kinds of diseases including diabetic nephropathy. Our study aimed to assess the therapeutic efficiency of exosomes secreted by hucMSC-exo on the rat model with diabetic nephropathy (DN). Rats were given an intraperitoneal injection of streptozotocin (60 mg/kg) to induce diabetes, while rats in blank gro

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Krämer, Stephanie, Yingrui Wang-Rosenke, Valeska Scholl, et al. "Low-dose mTOR inhibition by rapamycin attenuates progression in anti-thy1-induced chronic glomerulosclerosis of the rat." American Journal of Physiology-Renal Physiology 294, no. 2 (2008): F440—F449. http://dx.doi.org/10.1152/ajprenal.00379.2007.

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Treatment options in human mesangioproliferative glomerulonephritis/sclerosis, mostly IgA nephropathy, are limited. Progressive mesangioproliferative nephropathy represents a major cause of end-stage kidney disease. The present study explores the efficacy of low-dose mTOR inhibition by rapamycin in a chronic-progressive model of mesangioproliferative glomerulosclerosis (cGS). cGS was induced by high-dose anti-thy1 antibody injection into uninephrectomized rats. Rapamycin administration (2.5 mg·kg−1·body wt−1) was started 10 days after antibody injection and continued until week 20. cGS was cha

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C., Ojimelukwe,, Duru, C. A., Nnaoma, I. E., et al. "Effect of Odogwu Bitters on Biochemical Indices of Albino Rats." Saudi Journal of Biomedical Research 10, no. 01 (2025): 60–75. https://doi.org/10.36348/sjbr.2025.v10i01.007.

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The study assessed the impact of Odogwu bitters on biochemical indices of rats. In this experimental study, 16 adult male rats were used. The rats were randomly divided into four (4) groups. Groups 1-3 were given 100, 200, and 400mg/kg of Odogwu bitters. Group 4 served as the normal control. Serum liver enzyme activity, kidney function enzyme activity, Lipid profile test and haematology tests were carried out. The collected data were analyzed using SPSS, ANOVA, and LSD tests. Elevated levels of ALT and AST in rat plasma indicated potential liver tissue stress due to herbal exposure, aligning w

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Medeiros, Paulo José de, Arthur Villarim Neto, Francisco Pignataro Lima, Ítalo Medeiros Azevedo, Layra Ribeiro de Sousa Leão, and Aldo Cunha Medeiros. "Effect of sildenafil in renal ischemia/reperfusion injury in rats." Acta Cirurgica Brasileira 25, no. 6 (2010): 490–95. http://dx.doi.org/10.1590/s0102-86502010000600006.

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PURPOSE: To evaluate the effect of sildenafil, administered prior to renal ischemia/reperfusion (I/R), by scintigraphy and histopathological evaluation in rats. METHODS: Twenty-four rats were divided randomly into two groups. They received 0.1 ml of 99mTechnetium-etilenodicisteine intravenous, and a baseline (initial) renal scintigraphy was performed. The rats underwent 60 minutes of ischemia by left renal artery clamping. The right kidney was not manipulated. The sildenafil group (n=12) received orally 1 mg/kg of sildenafil suspension 60 minutes before ischemia. Treatment with saline 0.9% in

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Zahner, Matthew R., Ewa Kulikowicz, and Lawrence P. Schramm. "Recovery of baroreflex control of renal sympathetic nerve activity after spinal lesions in the rat." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 301, no. 5 (2011): R1584—R1590. http://dx.doi.org/10.1152/ajpregu.00295.2011.

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Spinal cord injury (SCI) has serious long-term consequences on sympathetic cardiovascular regulation. Orthostatic intolerance results from insufficient baroreflex regulation (BR) of sympathetic outflow to maintain proper blood pressure upon postural changes. Autonomic dysreflexia occurs due to insufficient inhibition of spinal sources of sympathetic activity. Both of these conditions result from the inability to control sympathetic activity caudal to SCI. It is well established that limited motor ability recovers after incomplete SCI. Therefore, the goal of this study was to determine whether

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Yu, Yeon Hee, Seong-Wook Kim, Dae-Kyoon Park, Ho-Yeon Song, Duk-Soo Kim, and Hyo-Wook Gil. "Altered Emotional Phenotypes in Chronic Kidney Disease Following 5/6 Nephrectomy." Brain Sciences 11, no. 7 (2021): 882. http://dx.doi.org/10.3390/brainsci11070882.

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Increased prevalence of chronic kidney disease (CKD) and neurological disorders including cerebrovascular disease, cognitive impairment, peripheral neuropathy, and dysfunction of central nervous system have been reported during the natural history of CKD. Psychological distress and depression are serious concerns in patients with CKD. However, the relevance of CKD due to decline in renal function and the pathophysiology of emotional deterioration is not clear. Male Sprague Dawley rats were divided into three groups: sham control, 5/6 nephrectomy at 4 weeks, and 5/6 nephrectomy at 10 weeks. Beh

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Furuya, Hajime, Toshihisa Kimura, Makoto Murakami, Kanji Katayama, Kazuo Hirose, and Akio Yamaguchi. "Revascularization and Function of Pancreatic Islet Isografts in Diabetic Rats following Transplantation." Cell Transplantation 12, no. 5 (2003): 537–44. http://dx.doi.org/10.3727/000000003108746993.

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In pancreatic islet transplantation, revascularization is crucial for the graft's survival and function. In this study, the endothelium of isolated islets and revascularization and function of islet isografts in diabetic rat were investigated. Islets were isolated from Lewis rats by collagenase digestion method and were examined using immunohistochemistry (CD31 stain) on days 0, 1, 3, and 7 after isolation. The number of CD31-positive cells in these isolated islets was counted (mean ± SD%). Isografts (freshly isolated islets: group A, and islets cultured for 7 days: group B) transplanted in th

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Ahmad, Saleh, Saeedur Rehman, Qazi Ikramullah, and Iqbal Ahmad. "Frequency of anemia in patients with Pulmonary Tuberculosis." International Journal of Endorsing Health Science Research 11, no. 4 (2023): 171–78. http://dx.doi.org/10.29052/ijehsr.v11.i4.2023.171-178.

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Background: Tuberculosis affects millions of people across the globe annually. Pakistan is ranked 5th among the leading TB countries in the world. Anemia is a common observation among TB patients with the multifactorial phenomenon. The present study aimed to determine the frequency of anemia in patients with pulmonary TB and its classification as per the severity and morphological characteristics. Methodology: This retrospective cross-sectional study was conducted at DHQ Hospital Timergara, Lower Dir. A total of 109 TB patients were enrolled and underwent physical and systemic examination. Blo

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Gloria, N. Elemo, O. Malik Lasisi, B. Mercy Adekunle, A. Prosper Akinleye, and T. Precious Bello. "Biochemical Evaluation of Vernonia amygdalina on the Haematology, Kidney Profile and Liver Function Tests in Wistar Rats." International Journal of Innovative Science and Research Technology 8, no. 5 (2023): 581–89. https://doi.org/10.5281/zenodo.7950874.

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Obesity and overweight contribute significantly to the burden of chronic diseases and complications globally. The rising prevalence of these conditions in Nigeria, especially among middle-class workers has been attributed to the acculturation of Western dietary patterns, reduced intake of dietary fibre, and sedentary lifestyles. Considering the risks associated with obesity and the associated side effects of orthodox medicine, a lot of studies have been dedicated to finding alternative treatments with limited side effects that are affordable hence, the use of medicinal plants such as Vernonia

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Zhao, Zhihong, Guixiang Liao, Qin Zhou, Daoyuan Lv, Harry Holthfer, and Hequn Zou. "Sulforaphane Attenuates Contrast-Induced Nephropathy in Rats via Nrf2/HO-1 Pathway." Oxidative Medicine and Cellular Longevity 2016 (2016): 1–12. http://dx.doi.org/10.1155/2016/9825623.

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Background. Oxidative stress plays an important role in the pathogenesis of contrast-induced nephropathy (CIN). The aim of this study was to investigate the antioxidant effects of sulforaphane (SFN) in a rat model of CIN and a cell model of oxidative stress in HK2 cells.Methods. Rats were randomized into four groups (n=6per group): control group, Ioversol group (Ioversol-induced CIN), Ioversol + SFN group (CIN rats pretreated with SFN), and SFN group (rats treated with SFN). Renal function tests, malondialdehyde (MDA), and reactive oxygen species (ROS) were measured. Western blot, real-time po

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