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1

Vangermeersch, Richard. "THE DIAGRAM OF THE COST SYSTEM OF HANS RENOLD LTD. — A BLUEPRINT FOR ACCOUNTING FOR ROBOTS." Accounting Historians Journal 14, no. 1 (1987): 27–31. http://dx.doi.org/10.2308/0148-4184.14.1.27.

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Knowledge of accounting history can be a great aid in solving accounting problems of today and tomorrow. One example of this is the use of a cost diagram of Church and Renold and the writings of Church to solve the problem of accounting for robots.
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2

Boyns, Trevor. "IN MEMORIAM: ALEXANDER HAMILTON CHURCH'S SYSTEM OF ‘SCIENTIFIC MACHINE RATES’ AT HANS RENOLD LTD., c.1901 - c.1920." Accounting Historians Journal 30, no. 1 (2003): 1–44. http://dx.doi.org/10.2308/0148-4184.30.1.3.

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In 1901, Alexander Hamilton Church wrote a path-breaking article in The Engineering Magazine, entitled ‘The proper distribution of establishment charges’. This article, published in six parts, is generally considered to have been one of the most important articles on the subject of overhead allocation and Church's system of scientific machine rates is often seen as a precursor of work which eventually resulted in the emergence of standard costing. Around the same time, Church introduced his system at Renold, a firm of British chain manufacturers, where it was used well into the First World War
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3

Falcioni, Alice, Angela Troisi, Luca Casadio, Antonio Chiaravalloti, Maria Teresa Minguzzi, and Federico Marchetti. "Quando la febbre non ha una chiara localizzazione: pensa anche alla nefrite focale acuta." Medico e bambino 40, no. 3 (2021): 186–88. http://dx.doi.org/10.53126/meb40186.

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Acute lobar nephronia, Diagnosis, Magnetic resonance imaging, Case report Acute lobar nephronia (ALN) is a non-suppurative focal form of acute bacterial infection, generally affecting one or more renal lobules. In the spectrum of upper urinary tract infection ALN is consid-ered a midpoint between uncomplicated pyelonephritis and intrarenal abscess. This condition may be difficult to recognize due to the lack of specific symptoms and laboratory findings. The reported incidence of ALN has increased as a result of advancements in non-invasive imaging techniques such as renal ultrasonography. Comp
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4

Butac, Mădălina. "PLUM VARIETIES USED AS PARENTS IN ROMANIAN BREEDING PROGRAM." Fruit Growing Research 37, no. 37 (2021): 6–13. http://dx.doi.org/10.33045/fgr.v37.2021.01.

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There are about three thousand varieties belonging to Prunus domestica available at present worldwide that can be used as genitors in plum breeding activity. An analysis of the pedigrees of plum cvs. developed in Romanian breeding programs shows that the most are descended from ‘Tuleu gras’, ‘Renclod Althan’, ‘Anna Späth’, ‘Stanley’ and ‘Early Rivers’, called 'ancestors'. That means the majority of plum cvs. have at least one of the ancestors as parent or grandparent. For those 40 plum cvs. registered in Romania in 60 years an increased number of crosses with these 'ancestors' has led to what
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Brunner-López, Olga, Maria Jesús Fuentes Martin, Berta Ortigosa-Pezonaga, A. M. López-García, and Grupo GE-NutPedia. "Texturas evolutivas en la introducción de nuevos alimentos: un acercamiento teórico." Revista Española de Nutrición Humana y Dietética 23, no. 2 (2019): 104. http://dx.doi.org/10.14306/renhyd.23.2.459.

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En la actualidad, existe un debate sobre el mejor método a elegir para iniciar la alimentación del lactante. Los modelos analizados para llevar a cabo la alimentación son: la alimentación con textura modificada dirigida por los padres o cuidadores y la alimentación con textura mínimamente modificada y dirigida por el bebé como los métodos baby-led weaning (BLW) y baby lead introduction to solids (BLISS). Este documento, tiene como finalidad ayudar, desde el punto de vista teórico, en el debate sobre las posibles texturas a utilizar en cada momento, atendiendo a diferentes factores, como son: e
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6

Sciarrone Alibrandi, Maria Teresa, and Marta Vespa. "Rene, ADPKD e COVID-19: il doppio ruolo della fragilità renale." Giornale di Clinica Nefrologica e Dialisi 32, no. 1 (2020): 99–101. http://dx.doi.org/10.33393/gcnd.2020.2165.

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The Corona Virus Disease 19 (COVID19) is an infectious disease caused by SARS – CoV – 2 (Severe Acute Respiratory Syndrome Coronavirus 2). By now, the pandemic has already led 318000 people to their death and our knowledge of this pathogen is still in its infancy. What we know so far is that older patients suffering from different comorbidities, such as heart failure, COPD and tumors, are keener to develop severe complications from which they might perish. The role of chronic kidney disease is still not clear, though. What we do know is that CKD patients are more susceptible to infections, bot
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7

Suheryanto, Zainal Fanani, and Dewi Jayanti. "Determination of copper metals in leachate using potentiometric method by concentration cells." SHS Web of Conferences 49 (2018): 02018. http://dx.doi.org/10.1051/shsconf/20184902018.

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The potentiometric method of cell type concentration is used to analyze the copper metal in leachate. This method is relatively good because it has a correlation coefficient of 0.9997 and linear region in the concentration range 1×10-5 1×10-3 mol L-1. The precision of this potentiometric method is low because the persent of RSD produced is 0.6% with an average accuracy 0f 95.35%. The detection limit (LoD) of the measurable method is 1.085×10-6 mol L-1 with LoQ 1.313×10-6 mol L-1. While the LoD instrument 1.217×10-6 mol L-1 and LoQ 1.560×10-6 mol L-1. In addition, this method is very selective
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8

Tsalouchos, Aris. "Inibitori del cotrasportatore sodio-glucosio di tipo 2 in pazienti sottoposti a trapianto renale." Giornale di Clinica Nefrologica e Dialisi 35 (November 23, 2023): 73–81. http://dx.doi.org/10.33393/gcnd.2023.2620.

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Several recent randomized controlled trials (RCTs) have demonstrated the broad clinical application of sodium-glucose cotransporter-2 inhibitors (SGLT2i) in improving kidney and cardiovascular outcomes in patients with native kidney disease. In January 2023, Dapagliflozin became the first SGLT2 inhibitor approved by the Italian Medicines Agency Administration (AIFA) for the treatment of chronic kidney disease (CKD) regardless of diabetic status. However, although these agents have received considerable praise for their cardiovascular and nephroprotective effects among patients with native kidn
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9

Susanti, Dian, and Aniska Novita Sari. "Inventarisasi Ragam Tumbuhan Obat Berpotensi sebagai Anti Nyamuk." Jurnal Vektor Penyakit 13, no. 1 (2019): 7–20. http://dx.doi.org/10.22435/vektorp.v13i1.447.

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 The use of chemical pesticides for mosquito control has been widely known by the public. The negative impact of the use of chemical pesticides has led to the importance of finding anti-mosquito alternatives from medicinal plants. This research was descriptive research using qualitative methods to know the medicinal plant potentially as anti mosquitos which were used in Indonesia. Qualitative data or the parameters examined were following the type of medicinal plant, the number of uses of the medicinal plant, and user tribes. Activities performed were including analysis of a subs
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10

Iqbal, Gowhar, Lukram Sushil Singh, Maharshi Limbola, et al. "Understanding Fish Immunity and Innovative Vaccination Approaches in Aquaculture." Annual Research & Review in Biology 39, no. 11 (2024): 136–44. https://doi.org/10.9734/arrb/2024/v39i112162.

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Fish possess a unique immune system that, while somewhat similar to mammals, exhibits distinct characteristics. This review paper explains the complexities of fish immunity, highlighting the innate and adaptive immune responses that protect against various pathogens, including bacteria (Aeromonas spp, Flavobacterium columnare, Mycobacterium marinum, Streptococcus iniae, Edwardsiella tarda, Pseudomonas aeruginosa etc), viruses (Infectious Hematopoietic Necrosis Virus (IHNV), Viral Hemorrhagic Septicemia Virus (VHSV) etc.), fungi and parasites (Dioctophyma renale etc). Host-pathogen interactions
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11

Aljumaah, Ali Sulaiman, Ebtsam Ibrahim Fallatah, Marwa Saad Althalabi, et al. "Chronic Renal Failure in Hemodialysis Patients." International Journal Of Pharmaceutical And Bio-Medical Science 02, no. 12 (2022): 658–62. http://dx.doi.org/10.47191/ijpbms/v2-i12-13.

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Objective: This study was a retrospective cross-sectional examination. Methods: The study enrolled 301 patients in 2018 who were referred to dialysis clinic. Data is collected through a series of questions about demographics (gender, age, education, employment, housing, marital status) and a checklist for causes of chronic renal failure (hypertension, diabetes, kidney disease, etc.). The Chi-square test, Fisher's exact test, analysis of variance (ANOVA), and SPSS version 24 were utilized to carry out inferential statistics. Results: Patients on hemodialysis typically develop chronic renal fail
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12

Ali, Sulaiman Aljumaah, Ibrahim Fallatah Ebtsam, Saad Althalabi Marwa, et al. "Chronic Renal Failure in Hemodialysis Patients." INTERNATIONAL JOURNAL OF PHARMACEUTICAL AND BIO-MEDICAL SCIENCE 02, no. 12 (2022): 658–62. https://doi.org/10.5281/zenodo.7462958.

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<strong>Objective:&nbsp;</strong>This study was a retrospective cross-sectional examination. &nbsp; <strong>Methods:&nbsp;</strong>The study enrolled 301 patients in 2018 who were referred to dialysis clinic. Data is collected through a series of questions about demographics (gender, age, education, employment, housing, marital status) and a checklist for causes of chronic renal failure (hypertension, diabetes, kidney disease, etc.). The Chi-square test, Fisher&#39;s exact test, analysis of variance (ANOVA), and SPSS version 24 were utilized to carry out inferential statistics. &nbsp; <strong>
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13

Brioni, Elena, Cristiano Magnaghi, Giulia Bruna Delli Zotti, et al. "Valutazione Del Benessere Psico-Fisico Nell’aderenza Terapeutica Nelle Donne Con Malattia Renale Policistica Autosomica Dominante: Uno Studio Osservazionale." Giornale di Clinica Nefrologica e Dialisi 31, no. 3 (2019): 160–66. http://dx.doi.org/10.33393/gcnd.2019.537.

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BACKGROUND: Autosomal dominant polycystic kidney disease is the most common inherited renal disease and affects less than 1 every 400-1,000 people. There are many effective treatments, including blood pressure management, physical activity, low sodium diet and hydration. Therapeutic education is part of a patient’s care and treatment. This approach is an essential strategy in order to face the current healthcare scenario, in which the number of people affected by chronic diseases is progressively increasing. OBJECTIVES: This article aims to analyze the effect of therapeutic education in patien
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14

Brioni, Elena, Cristiano Magnaghi, Giulia Bruna Delli Zotti, et al. "Valutazione Del Benessere Psico-Fisico Nell’aderenza Terapeutica Nelle Donne Con Malattia Renale Policistica Autosomica Dominante: Uno Studio Osservazionale." Giornale di Tecniche Nefrologiche e Dialitiche 31, no. 3 (2019): 160–66. http://dx.doi.org/10.1177/0394936219858903.

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Evaluation Of The Psychophysical Well-Being In The Compliance Of Women With Autosomal Dominant Policystic Kidney Disease: An Observational Study BACKGROUND: Autosomal dominant polycystic kidney disease is the most common inherited renal disease and affects less than 1 every 400-1,000 people. There are many effective treatments, including blood pressure management, physical activity, low sodium diet and hydration. Therapeutic education is part of a patient’s care and treatment. This approach is an essential strategy in order to face the current healthcare scenario, in which the number of people
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15

Thornton, Mark. "Rethinking Criminal Law Theory: New Canadian Perspectives in the Philosophy of Domestic, Transnational, and International Law edited by François Tanguay-Renaud and James Stribopoulos Oxford and Portland, Oregon, Hart Publishing Ltd, 2012. ISBN 978-1-84946-010-1. xii + 321 pp." Canadian Journal of Law & Jurisprudence 26, no. 1 (2013): 243–48. http://dx.doi.org/10.1017/s0841820900006032.

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Professor John Gardner says on the jacket, “these essays – without exception insightful and penetrating – set a high standard for the rest of us to aspire to.” This collection of 15 essays by 16 Canadian authors originated in a conference at Osgoode Hall Law School, York University. The majority of contributors are based in southern Ontario (Osgoode or York 5, Western 3, Toronto 2, and Queen’s 1). Two are from western Canada (Alberta, Saskatchewan), two from the UK (Manchester, Oxford) and one from the US (Cornell). The essays are arranged in three parts, the first being subdivided according t
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16

Nilay, N. Suthar, and P. Verma Anita. "ALKALINE DIET AND HEALTH-A BRIEF REVIEW." International Journal of Basic & Applied Physiology 3, no. 1 (2014): 22–30. https://doi.org/10.5281/zenodo.4472487.

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Plenty has been researched in modern medicine about the pH of foods, but the basic thought about the injury causing food has not been reviewed in most of the literature. Compared to our ancestors it has been investigated that the composition of the food we are taking now has changed dramatically. Increased propensity of acid-forming food has substantially increased burden on the natural buffering system of the body. More and more consumption of acid-forming food has led to a tremendous pressure on the body&rsquo;s defence against acidosis-acidaemia. In this review article the significance of a
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17

International, Journal of Medical Science and Innovative Research (IJMSIR). "Clinical Profile of Renal Donor Undergoing Donor Nephrectomy in A Tertiary Care Hospital in India." International Journal of Medical Science and Innovative Research (IJMSIR) 9, no. 6 (2024): 85–88. https://doi.org/10.5281/zenodo.15449548.

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<strong>Abstract</strong> Living kidney donation(LKD) is increasing in frequency reflecting and overall increase in transplantation activity in India. However, the frequency varies in different parts depending on scientific, cultural, and ethical factors. Clinical data regarding the clinical profile of renal donor in India is less compared to western literature. The study aims to increase the knowledge regarding the clinical profile of the donor coming to a tertiary care centre in India.&nbsp; Renal donor presenting to Mahatma Gandhi hospital Jaipur from June 2022 to April 2023 for renal trans
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18

Charbonneaux, Juliette. "Figures de la polyphonie européenne en régime médiatique (1918-2018)." Sur le journalisme, About journalism, Sobre jornalismo 9, no. 1 (2020): 194–207. http://dx.doi.org/10.25200/slj.v9.n1.2020.427.

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FR. L’article vise à mettre en lumière certains ressorts et figures du « journalisme européen » tel qu’il a pu être imaginé et mis en œuvre, en France, entre la première moitié du XXe siècle et aujourd’hui. Inscrite dans une perspective généalogique qui fait dialoguer ces deux époques, la démarche interroge ainsi l’ethos européen du journalisme à travers les « systèmes polyphoniques », soit les voix et plumes, qu’ont déployé deux séries de supports médiatiques (revues, magazines, journaux) affichant ou ayant affiché comme ambition la formation et la transmission d’un propos supranational. La p
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19

H.F., Baghirova, та Gadimova S.H. "Correction of Anemia in Patients With Renal Pathology in Pregravidal Рreparing". Journal of Life Sciences and Biomedicine 69, № 1 (2014): 104–9. https://doi.org/10.5281/zenodo.7443029.

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The studies have shown that the major pathogenetic factor in the development of anemia was an absolute deficiency of erythropoietin, which was observed in 46.6% of patients with chronic kidney disease stage 1, 58.1% - with chronic kidney disease stage 2 and 61.7% - with chronic kidney disease stage 3. Relative increase in the level of EPO at reduced Hb was greatest in patients with chronic kidney disease stage 1 and the lowest in patients with chronic kidney disease stage 3. Normochromic normocytic anemia was characteristic for most patients with renal disease. Increased serum concentrations o
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20

Iancu, Adina, and Mihai Chivu. "STUDY OF GENETIC DIVERSITY AND ANALYSIS OF THE DEGREE OF SIMILARITY IN SOME APPLE AND PLUM VARIETIES USING RAPD MARKERS." Fruit Growing Research 37, no. 37 (2021): 19–26. http://dx.doi.org/10.33045/fgr.v37.2021.03.

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Molecular evaluation of germplasm is an important step in breeding programs, and the application of molecular biological techniques has led to important results in terms of both within- and between-species variability of traits. The RAPD technique has been successfully used to reveal allelic polymorphism as well as to measure genetic similarity. In this study, the genetic diversity of 25 genotypes and cultivars for apple species and 26 genotypes and cultivars for plum species was assessed with six RAPD markers. All these cultivars belong to the ex situ collection of apple and the ex situ colle
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Piché-Renaud, Pierre-Philippe, Luc Panetta, Daniel Farrar, et al. "483. Disease Severity and Clinical Manifestations of SARS-CoV-2 Infection Among Infants Over the First Year of the Pandemic in Canada." Open Forum Infectious Diseases 8, Supplement_1 (2021): S342—S343. http://dx.doi.org/10.1093/ofid/ofab466.682.

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Abstract Background There is limited data on outcomes of SARS-CoV-2 infection among infants (&amp;lt; 1 year of age). In the absence of any approved vaccines for infants, understanding the risk factors for hospitalization and severe disease from COVID-19 in this age group will help inform clinical management and targeted public health interventions. The objective of this study was to describe the clinical manifestations, disease severity, and risk factors for hospitalization among infants with SARS-CoV-2 infection in Canada. Methods This is a nationwide prospective observational study using th
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Attila, Szöllösi. "Treatment difficulties during COVID 19 pandemic in a patient with giant renal tumor. A small town general hospital perspective." Journal of Surgical Case Reports and Images 4, no. 2 (2021): 01–06. http://dx.doi.org/10.31579/2690-1897/042.

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Introduction: We present an unusual case of papillary renal cell carcinoma, which is a rare subtype of kidney malignancy. Objective: The present case report emphasizes a voluminous left renal tumoral mass causing bowel obstruction and necessity of emergency surgical intervention. Presentation of case: A 74 year old patient with a history of multiple severe cardiovascular conditions, presented in the emergency room accusing abdominal distension and pain, nausea, vomiting and lack of intestinal transit for about 72 hours. Based on the symptomatology, physical examination and imagistic exploratio
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23

陳燁, 陳燁, та 陳珍緯 陳珍緯. "運用復原力於一位末期腎臟疾病病童之照護經驗". 臺灣腎臟護理學會雜誌 22, № 1 (2023): 015–27. http://dx.doi.org/10.53106/172674042023122201002.

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&lt;p&gt;本文描述一位十六歲末期腎臟疾病病童,於2010年開始血液透析治療,因病程複雜導致頻繁出入院,進而嚴重影響生活品質。臨床上透析病童少見,醫護人員缺乏照護經驗,故對症狀評估及執行護理措施等均有困難。護理其間於2020年6月20日至9月20日,透過聊天、遊戲等方法與案童建立良好治療性人際關係,藉由照護、觀察、身體評估等方式收集資料,評估案童四大層面健康問題,問題包含復原力障礙、舒適障礙及營養不均衡,運用復原力概念降低危險因子及提升保護因子,增加正向健康行為以適應疾病,啟動跨團隊照護改善其營養不均衡,運用舒適護理緩解不適症狀。建議護理人員運用關懷及復原力,賦能案童對自我照顧技巧,引導病童探索自我價值,以增強對疾病的適應與提升照護品質。&lt;/p&gt; &lt;p&gt;&amp;nbsp;&lt;/p&gt;&lt;p&gt;This article describes a 16-year-old child with end-stage renal disease who started hemodialysis in 2010. The severe and complicated disease led to frequent admissions and discharges, which seriously affected the quality of l
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Abhulimen, Victor, Okigbeye Danagogo, and Komene Monday Sapira. "Renal Cell Carcinoma: A Ten-Year Review in a Tertiary Institution in the Niger Delta." Greener Journal of Medical Sciences 13, no. 1 (2023): 4–16. https://doi.org/10.5281/zenodo.7674235.

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<strong>Background:</strong> Renal cell carcinoma (RCC) is an insidious neoplasm, accounting for approximately 2% of global cancer diagnoses and deaths, and is projected to increase in burden worldwide. Studies on renal malignancies in Port Harcourt are few and where present have focused on the pathology or the paediatric population. This study is on the presentation, risk factors and management of RCC in an adult population. <strong>Materials and Methods</strong>: This is a ten-year retrospective study conducted at the University of Port Harcourt Teaching Hospital. Ethical approval for the st
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Miklovic, Matus, Olga Gawrys, Zuzana Honetschlagerova, et al. "Renal denervation improves cardiac function independently of afterload and restores myocardial norepinephrine levels in a rodent heart failure model." Hypertension research 47, no. 10 (2024): 2718–30. https://doi.org/10.1038/s41440-024-01580-3.

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Renal nerves play a critical role in cardiorenal interactions. Renal denervation (RDN) improved survival in some experimental heart failure (HF) models. It is not known whether these favorable effects are indirect, explainable by a decrease in vascular afterload, or diminished neurohumoral response in the kidneys, or whether RDN procedure per se has direct myocardial effects in the failing heart. To elucidate mechanisms how RDN affects failing heart, we studied load-independent indexes of ventricular function, gene markers of myocardial remodeling, and cardiac sympathetic signaling in HF, indu
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Orakpoghenor, Ochuko. "Exploring the Hepato-Renal Impact of Lead Acetate and in Combination with Defatted Moringa oleifera Seed Meal in Wistar Rats." Clinical Pathology & Research Journal 8, no. 1 (2024): 1–7. http://dx.doi.org/10.23880/cprj-16000186.

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Lead acetate is recognized for its hepatorenal toxicity, causing harm to the liver and kidneys upon exposure through air, water, or food, thus, leading to severe health issues. Defatted Moringa oleifera seed meal (DMOSM) is valued for its health benefits by offering a protein-rich supplement with antioxidant properties, and serving as a sustainable source of plant-based protein. In this study, the impact of lead acetate exposure and the potential protective effects conferred by DMOSM in male Wistar rats were assessed. The rats were divided into five groups: negative control (Group I), lead ace
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Angieliza, Dominguez Villanueva. "A systematic review of patient education strategies for arteriovenous fistula care in hemodialysis patients." GSC Biological and Pharmaceutical Sciences 29, no. 2 (2024): 092–95. https://doi.org/10.5281/zenodo.14753313.

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Chronic kidney disease (CKD) poses a significant global health challenge, contributing to approximately 1.4 million deaths in 2019. As the prevalence of end-stage renal disease (ESRD) rises, effective management strategies, particularly hemodialysis and arteriovenous fistula (AVF) care, become paramount. This systematic review aims to evaluate various nurse-led patient education interventions focused on enhancing self-care practices and reducing complications associated with AVF. A comprehensive literature search across CINAHL Complete and PubMed yielded 344 articles, of which only six met the
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N, Inchara, Narayan M, and Praveen Kumar B A. "Ocular abnormalities in patients with chronic renal failure on haemodial-ysis: A study from a rural tertiary care teaching institute." JOURNAL OF CLINICAL AND BIOMEDICAL SCIENCES 10, no. 2 (2020): 52–56. http://dx.doi.org/10.58739/jcbs/v10i2.6.

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Background: Chronic Renal Failure (CRF) affects every organ system, including the eye. Potential vision-threatening ocular complications among patients with CRF can lead to irreversible visual impairment. Aims: We assess and report ocular abnormalities in patients with chronic renal failure on hemodialysis in a rural setup. Settings and Design: This is a cross-sectional hospital-based study conducted in a rural tertiary care institute. Methods and Material: One hundred twenty subjects undergoing dialysis in our institute for a period of 2 years were included in the study by convenient sampling
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Attinger-Toller, Isabella, Philipp Probst, Lia Kallenberger, et al. "Abstract LB124: Targeting NaPi2b with a novel dual TOP1i ADC that shows excellent biophysical properties and high efficacy in vivo." Cancer Research 84, no. 7_Supplement (2024): LB124. http://dx.doi.org/10.1158/1538-7445.am2024-lb124.

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Abstract The Araris site-specific and one-step linker conjugation technology aims at generating stable, safe and highly potent ADCs without the need for antibody engineering prior to payload conjugation. Here, we generated an anti-NaPi2b ADC with two different Topoisomerase-1 inhibitors (TOP1i) as payloads that shows excellent efficacy vs anti-NaPi2b ADCs that were unsuccessful in clinical trials due to low therapeutic indices (TI), preventing administration at therapeutically active doses. The Araris ADC was designed to combine two features in one ADC to maximize tumor-specific activity by us
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Agbara, A. C., M. P. Ajah, C. E. Offor, C. I. Anyaoku, O. D. Erhabor, and V.O. Nwobodo. "EFFECT OF CUCUMEROPSIS MANNI SEED OIL ON LIVER AND KIDNEY FUNCTION MARKERS OF CYCLOPHOSPHAMIDE INDUCED TOXICITY IN WISTAR ALBINO RATS." AnachemJournal 15, no. 1 (2024): 154–67. https://doi.org/10.5281/zenodo.14567533.

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This study evaluated the hepatic and renal properties of cucumeropsis manni seed oil on cyclophosphamide-induced toxicity in Wistar albino rats. Thirty-six male Wistar albino rats were randomly assigned into 6 groups (A, B, C, D, E, and F) of 6 rats each. Group A (normal control) received 5ml/kg b.w of normal saline for 28 days; Group B (negative control) received 5ml/kg b.w of normal saline for 27 days and 100 mg/kg b.w of cyclophosphamide at day 28 only. Group C (standard control) received 300 mg/kg b.w of Omega 3 oil for 27 days and 100 mg/kg b.w of cyclophosphamide on day 28. Group D recei
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Chavatte-Palmer, P., Y. Heyman, and I. Schwartz. "26 EFFECTS OF SOMATIC CLONING ON THE IMMUNE RESPONSE IN YOUNG AND ADULT CATTLE." Reproduction, Fertility and Development 18, no. 2 (2006): 121. http://dx.doi.org/10.1071/rdv18n2ab26.

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Somatic cloning in cattle is associated with important gestational abnormalities, including implantation delay during the first 2 months of pregnancy and abnormal fetal and placental growth (known as large offspring syndrome, or LOS) in the third trimester. In our laboratory, between 3 and 25% of the cloned blastocysts transferred to recipient cows reach term, depending on genotype. About 20% of the newborns die rapidly due to various causes that appear to be direct consequences of the LOS. We previously reported on a thymic atrophy resulting from nuclear transfer (Renard et al. 1999 Lancet 35
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Attinger-Toller, Isabella, Philipp Probst, Romain Bertrand, et al. "Abstract LB138: A novel dual-TOP1i ADC targeting NaPi2b designed for high efficacy and tolerability." Cancer Research 85, no. 8_Supplement_2 (2025): LB138. https://doi.org/10.1158/1538-7445.am2025-lb138.

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Abstract The Araris site-specific and one-step linker conjugation technology aims at generating stable, safe and highly potent ADCs without the need for antibody engineering prior to payload conjugation. Here we show data on a novel, multi-warhead anti-NaPi2b ADC armed with two different Topoisomerase-1 inhibitors (TOP1i) as payloads engineered for optimal efficacy and tolerability. The multi-warhead ADC was designed to maximize tumor-specific activity while balancing Exatecan toxicity by combining bystander-active Exatecan with a bystander-reduced Exatecan derivative that accumulates in cance
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Mukadder, Mollaoğlu. "Quality of Life in Patients with Chronic Renal Failure and Some Affecting Factors." Archives of Renal Diseases and Management 3, no. 1 (2017): 012–19. https://doi.org/10.17352/2455-5495.000020.

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<strong>Purpose:</strong>This study was conducted to determine the quality of life (QoL) in dialysis patients (DP) andthe factors affecting the QoL. <strong>Material and Methods:</strong> 104 DP patients receiving treatment at a university hospital were included in this research, which was also a cross-sectional study. Data were collected with the Patient Information Form (PIF) and Kidney Disease Quality of Life Form (KDQOL-36). Collected data were evaluated on SPSS. <strong>Result:</strong> The&nbsp; most&nbsp; affected&nbsp; QoL&nbsp; dimensions&nbsp; in&nbsp; the&nbsp; sampling&nbsp; were&n
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Levy, D., B. Nespola, M. Giannini, et al. "FRI0249 IN MYOSITIS PATIENTS, SJÖGREN’S SYNDROME IS ASSOCIATED WITH INCLUSION BODY MYOSITIS AND WITH ANTI-CN1A ANTIBODIES INDEPENDENTLY OF THE MYOSITIS SUBTYPE." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 708.3–709. http://dx.doi.org/10.1136/annrheumdis-2020-eular.5766.

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Background:Myositis are characterized by weakness and muscle inflammation. They encompass heterogeneous conditions, which include dermatomyositis (DM), inclusion body myositis (IBM) and polymyositis (PM) according to the EULAR/ACR 2017 criteria. We recently recorded a high prevalence of IBM in a cohort of primary Sjögren’s syndrome (SS) (1). The signification of SS in the setting of myositis is unanswered.Objectives:To refine the signification of SS in the setting of myositis.Methods:Among a monocentric myositis cohort (according to the EULAR/ACR 2017 criteria), SS patients (according to the A
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Attinger-Toller, Isabella, Philipp Probst, Romain Bertrand, et al. "Abstract 2910: A CD79b targeting ADC with superior anti-tumor activity and therapeutic index." Cancer Research 82, no. 12_Supplement (2022): 2910. http://dx.doi.org/10.1158/1538-7445.am2022-2910.

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Abstract The Araris’ site-specific and 1-step linker conjugation technology aims at generating safe and highly potent ADCs without the need for antibody engineering prior to linker-payload conjugation. We developed a very stable anti-CD79b-MMAE ADC with this technology showing a higher therapeutic index compared to polatuzumab-vedotin in preclinical models. Our ADC may represent a safe and efficacious alternative for the treatment of patients with diffuse-large B-cell lymphoma (DLBCL).Using native polatuzumab (non-engineered, same antibody sequence as present in approved polatuzumab-vedotin) a
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Attinger-Toller, Isabella, Philipp Probst, Romain Bertrand, et al. "Abstract 7334: Targeting Nectin-4 with a first-in-class triple MMAE/dual TOP1i payload ADC showing synergistic and durable activity across all target expression levels and favorable tolerability." Cancer Research 85, no. 8_Supplement_1 (2025): 7334. https://doi.org/10.1158/1538-7445.am2025-7334.

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Abstract The Araris’ site-specific and one-step linker conjugation technology aims at generating stable, safe and highly potent ADCs without the need for antibody engineering prior to payload conjugation. We here present a novel Nectin-4 targeting triple-warhead ADC using a combination of MMAE and two different topoisomerase-1 inhibitors (TOP1i, DAR2+2+2) designed to treat a broad range of Nectin-4 expressing solid tumors. With this novel ADC we aim to 1) effectively kill heterogenous and resistant tumors by delivering multiple cytotoxic payloads to the same tumor cell, 2) control and limit by
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Evridawati, Beryana, Yufiarti, and Elindra Yetti. "The Cognitive Style and Attachment on Early Childhood Speech Skills." JPUD - Jurnal Pendidikan Usia Dini 14, no. 1 (2020): 32–42. http://dx.doi.org/10.21009/jpud.141.03.

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&#x0D; &#x0D; &#x0D; Concurrently with the rapid development in digital society, the demand for communication skills was clear in childhood. Early childhood education needs to pay attention to children's speech skills development. This study aims to determine the effect of cognitive style and attachment on the ability to speak in early childhood speech development. The method used is a 2 x 2 factorial comparison design which is divided into two groups namely independent and dependent fields involving 138 samples. Re- search findings about differences in the ability to speak early childhood who
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Zhou, Jianwei. "Study of the Association between Helicobacter Pylori Infection and Primary open angle Glaucoma in China." International Journal of Immunology and Microbiology 1, no. 1 (2021): 1–4. http://dx.doi.org/10.55124/ijim.v1i1.30.

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Objective: To assess the relationship between Helicobacter pylori (Hp) infection and primary open-angle glaucoma (POAG); and meantime, to explore the possible mechanism of POAG induced by Hp. Methods: 30 consecutive POAG patients, 30 primary angle-closure glaucoma (PACG) and cataract patients were recruited and divided into three groups according to different diseases. The sera and aqueous humor samples were collected and used to detect Hp-specific IgG antibody (Hp-Ab) with dot immunogold filtration assay (DIGFA). 14C-urea breath test (14C-UBT) was carried out to detect Hp infection of all par
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K., Ramaiah, Sivasankar R., Sreenivasulu G., et al. "Significance of red grape extract on oxidative enzymes in the brain of male albino rat with reference to aging." Biolife 3, no. 2 (2022): 451–60. https://doi.org/10.5281/zenodo.7269502.

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<strong>ABSTRACT</strong> Nicotine has been reported to induce oxidative stress by producing the Reactive Oxygen Species (ROS). In vitro studies showed that Red grape extract has significant antioxidant activity and can inhibit oxidation. Pathogen free, Wistar strain male albino rats were used in the present study, rats were divided into 4 groups of six rats in each group and treated as follows: Group I. Normal Control (NC) (Control rats received 0.9% saline). Group II. Nicotine treated (Nt) (at a dose of 0.6 mg/ kg body weight by subcutaneous injection for a period of 2 months). Group III. Re
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Adeoti, Olatunde Micheal, Abidemi Hawawu Bello, Olajumoke Elisabeth Adedokun, Kafilat Adenike Komolafe, David Ademola Adesina, and Opeyemi Joy Olaoye. "Distinctive Molecular typing of 16S rRNA of Bacillus species isolated from farm settlement." International Journal of Immunology and Microbiology 1, no. 1 (2021): 10–15. http://dx.doi.org/10.55124/ijim.v1i1.55.

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Introduction: There are numerous methods of isolating and detecting organisms that are similar and closely related; one of the most reliable method is molecular typing of 16S rRNA. Apart from being omnipresent as a multigene family, or operons; it is evolutionarily stable; the 16S rRNA gene (1,500 bp) is large enough for informatics purposes.&#x0D; Materials and Method: This study employed molecular sequencing of 16S rRNA by Sanger method to reveal the specific organisms’ nucleotides and blasting (BLASTn) to show the similarities between the resulting organisms and existing organisms. The 16S
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Hens, Luc, Nguyen An Thinh, Tran Hong Hanh, et al. "Sea-level rise and resilience in Vietnam and the Asia-Pacific: A synthesis." VIETNAM JOURNAL OF EARTH SCIENCES 40, no. 2 (2018): 127–53. http://dx.doi.org/10.15625/0866-7187/40/2/11107.

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Climate change induced sea-level rise (SLR) is on its increase globally. Regionally the lowlands of China, Vietnam, Bangladesh, and islands of the Malaysian, Indonesian and Philippine archipelagos are among the world’s most threatened regions. Sea-level rise has major impacts on the ecosystems and society. It threatens coastal populations, economic activities, and fragile ecosystems as mangroves, coastal salt-marches and wetlands. This paper provides a summary of the current state of knowledge of sea level-rise and its effects on both human and natural ecosystems. The focus is on coastal urban
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Yasar, Busra, Yalcin Isler, and Nermin Topaloglu Avsar. "Manufacturing Multicolor LED-Based Phototherapy Device with a Novel 3D Design." Journal of Intelligent Systems with Applications, December 27, 2021, 120–24. http://dx.doi.org/10.54856/jiswa.202112174.

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Jaundice is a condition that results from an increase in bilirubin level in the blood. Its prevalence in newborns is around 60-70%. When this temporary jaundice becomes pathological and left untreated, significant damages may occur such as brain damage, vision loss, lung and kidney dysfunction, and even death. One of the methods used for the treatment of jaundice is phototherapy. In this study, a design has been made with 3 foldable LED panels to increase the target area. In addition, high-voltage LEDs with blue-green white wavelengths were used. Thus, it was aimed to minimize the risks of nau
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Topaloglu Avsar, Nermin, Ufuk Balkaya, and Ziysan Buse Yarali Cevik. "Design of Portable Multicolor LED-Based Optical System for the Photobiomodulation Therapy on Wound Healing Process." Journal of Intelligent Systems with Applications, May 2, 2021, 61–67. http://dx.doi.org/10.54856/jiswa.202105159.

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Photobiomodulation is a practical and noninvasive treatment that triggers cell proliferation, cell differentiation, wound healing, new tissue formation, inflammation and pain reduction with low-level light therapy. Light-emitting diodes (LEDs) are energy-saving, affordable and safe alternatives to laser devices which are recently preferred in photobiomodulation. Although the wavelengths between 600-700 nm are most preferred ones, there is a lack of practical optical systems which study this mechanism in vitro with different wavelengths simultaneously. In this study, a portable and remotely con
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"Update sulla malattia renale diabetica (DKD): focus sulla DKD non albuminurica e il rischio cardiovascolare." Il Diabete 35, no. 4 (2024). http://dx.doi.org/10.30682/ildia2304a.

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The classic description of diabetic kidney disease (DKD) involves progressive stages of glomerular hyperfiltration, microalbuminuria, and a decline in the estimated glomerular filtration rate (eGFR). However, large studies have revealed that eGFR decline may also occur independently from development of albuminuria. This concept led to the identification of a new phenotype: non-albuminuric DKD, whose pathogenesis is still unknown and data in literature are still controversial. This review is focused on cardiovascular risk profile and therapeutical implication of this new DKD phenotype.
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Tiquet, Romain. "‘Tracing’ Jean-Louis Renauld: Private Archives as a Way into the History of a Post-Colonial Psychiatric Unit (Bobo-Dioulasso, Upper Volta, 1972-1974)." Sources 8 (2024). http://dx.doi.org/10.4000/12n0w.

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This text presents an incursion into the history of the Bobo-Dioulasso psychiatric unit a decade after Upper Volta gained independence, through the career and experience of Jean-Louis Renauld, a psychiatrist and psychoanalyst who worked at the unit between 1972 and 1974, within the framework of the French coopération programme. The present article draws on a corpus of varied sources: various interviews carried out with Jean-Louis Renauld, around fifteen photographs taken during his stay, and a small collection of private archives put together by the psychiatrist himself. This latter corpus con
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Ignacio, Fernández Vidaurreta. "Uso de empagliflozina en pacientes con enfermedad renal crónica." ACTUALIZACIÓN EN MEDICINA CLÍNICA 4, no. 60 (2023). https://doi.org/10.5281/zenodo.7924913.

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Se dise&ntilde;&oacute; el estudio EMPA-KIDNEY para evaluar los efectos del tratamiento con empagliflozina en pacientes con enfermedad renal cr&oacute;nica. Demostr&oacute; que su uso conllev&oacute; un menor riesgo de progresi&oacute;n de la enfermedad o de muerte por causas cardiovasculares, en comparaci&oacute;n con el tratamiento con placebo. &nbsp; &nbsp; <em>The EMPA-KIDNEY trial was designed to assess the effects of treatment with empagliflozin in patients with chronic kidney disease. This empagliflozin therapy led to a lower risk of progression of kidney disease or death from cardiovas
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Alnamshan, M. M. "Antioxidant extract of black rice prevents renal dysfunction and renal fibrosis caused by ethanol-induced toxicity." Brazilian Journal of Biology 82 (2022). http://dx.doi.org/10.1590/1519-6984.261874.

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Abstract This study was conducted to evaluate the protective role of extracted natural antioxidants from black rice and their effect on kidney failure and renal cirrhosis caused by ethanol-induced toxicity. Antioxidant activity in terms of total phenol content, flavonoid compounds and anthocyanin, as well as antioxidant capacity, was determined in an extract of black rice. The findings noted that the black rice extract contained high amounts of antioxidant activity and capacity. Total phenolic compounds from black rice extract were fractionated using HPLC and the results showed that ferulic, s
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Brioni, Elena, Cristiano Magnaghi, Zotti Giulia Bruna Delli, et al. "Valutazione Del Benessere Psico-Fisico Nell'aderenza Terapeutica Nelle Donne Con Malattia Renale Policistica Autosomica Dominante: Uno Studio Osservazionale." July 2, 2019. https://doi.org/10.1177/0394936219858903.

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Evaluation Of The Psychophysical Well-Being In The Compliance Of Women With Autosomal Dominant Policystic Kidney Disease: An Observational Study BACKGROUND: Autosomal dominant polycystic kidney disease is the most common inherited renal disease and affects less than 1 every 400-1,000 people. There are many effective treatments, including blood pressure management, physical activity, low sodium diet and hydration. Therapeutic education is part of a patient's care and treatment. This approach is an essential strategy in order to face the current healthcare scenario, in which the number of people
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BERGENSTAL, RICHARD M., STEVEN EDELMAN, PRATIK CHOUDHARY, et al. "105-LB: Glucose Variability with Second-Generation Basal Insulin Analogs Glargine 300 U/mL and Degludec 100 U/mL, Evaluated by CGM in People with T1D—The InRange Randomized Controlled Trial." Diabetes 71, Supplement_1 (2022). http://dx.doi.org/10.2337/db22-105-lb.

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Background: InRange has previously demonstrated that insulin glargine 300 U/mL (Gla-300) is non-inferior to insulin degludec 100 U/mL (IDeg-100) in terms of time in glucose range 70--180 mg/dL (primary endpoint) and total glucose coefficient of variation (CV) as measured by CGM in people with T1D. Methods: InRange (NCT04075513) was a multicenter, randomized, active-controlled, parallel-group, 12-week open-label trial comparing Gla-300 vs. IDeg-100 in adults with T1D using 20-day CGM profiles (≥10 days evaluable) . Here we present data for within- and between-day CV. Results: Overall, 343 parti
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Dr.Amjad, Ali Hulio Dr. Syed Fasih Ahmed Hashmi Dr. Mashooq Ali Dasti Dr. Shayan Qasim and Dr. Zulfiqar Ali Qutrio Baloch. "IMPACT OF PERCUTANEOUS CORONARY INTERVENTION IN PATIENTS WITH MILD RENAL DYSFUNCTION AND ITS IMPACT ON IN-HOSPITAL OUTCOME." iajps,csk publications 04, no. 01 (2017). https://doi.org/10.5281/zenodo.293710.

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Objective: To observe impact of percutaneous coronary intervention in patients with mild renal dysfunction and its impact on inhospital outcome. Patients and Methods: This is descriptive case series study conducted at department of Cardiology at Liaquat University Hospital, Jamshoro From 11-02-2015 to 11-08-2015. Total 50 patients who satisfy KDOQI criteria for mild renal disease and underwent PCI were included in the study. Contrast medium was injected. Pre and post PCI level of serum creatinine was estimated. GFR was calculated by CKD-EPI equation. Patient was discharge after seven days and
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