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Dissertations / Theses on the topic 'Replikon'

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Published: 4 June 2025

Last updated: 1 August 2025

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1

Gabler, Maximilian. "DNA Replicons next generation vaccines against allergy." Saarbrücken VDM Verlag Dr. Müller, 2005. http://d-nb.info/988936151/04.

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2

Llanes, Catherine. "Plasmides de resistance de serratia marcescens : typage de replicons, clonage et sequencage du replicon repa/c." Besançon, 1993. http://www.theses.fr/1993BESA3709.

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3

Renberg, Miranda. "Replika på replika." Thesis, Konstfack, Ädellab, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:konstfack:diva-7792.

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I’m interested in the way we stage our identity through objects. How objects relate to identity and body. I have been looking into how the self conception and creation of identity is affected by living in an individualistic, capitalistic and mass medial time. I carry a question, how much of the self is really just a replica of a replica? In this essay I discuss how the consumption of different kinds of media gives us knowledge and experiences of the world that is secondary. I explain how I experience that social media creates a thinking where I’m looking at my self from the outside and that th

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4

Krejčí, Kamil. "Výroba repliky motoru Laurin-Klement." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2009. http://www.nusl.cz/ntk/nusl-228574.

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The goal of the graduation thesis is building of a working replica of the motorcycle engine Laurin&Klement, type TB from 1902. The thesis focuses on the manufacturing of cast parts. The piece production of the engine has been based on extant original pieces, missing pieces have been manufactured according to period photographs and leaflets. This method can be applied for production of missing or damaged pieces of historical motorcycles‘ engines.

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5

Tatley, Fernanda Maria Palma Ribeiro da Silva. "Characterisation of a replicon of the conjugative, multiple drug resistance, moderately promiscuous, plasmid pGSH500." Thesis, University of Cape Town, 1992. http://hdl.handle.net/11427/25668.

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6

Gomes, de Oliveira Amanda. "Desenvolvimento e aplicação biotecnológica de replicons repórteres para triagem de drogas antivirais contra o vírus da febre amarela." Universidade Federal de Pernambuco, 2011. https://repositorio.ufpe.br/handle/123456789/6092.

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Made available in DSpace on 2014-06-12T18:01:54Z (GMT). No. of bitstreams: 2 arquivo3099_1.pdf: 5591692 bytes, checksum: 07230239ef4ede2c2128b63b2068f8bc (MD5) license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) Previous issue date: 2011<br>Faculdade de Amparo à Ciência e Tecnologia do Estado de Pernambuco<br>A re-emergência da febre amarela e sua significância como um problema de saúde pública tem gerado um interesse para o desenvolvimento de novas ferramentas vacinais e agentes antivirais contra este vírus. Drogas antivirais, específicas para o vírus da febre amarela,

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7

Kanak, Alison Elizabeth. "Induction of Apoptosis by Rubella Virus Non-Structural Replicase and Rescue by Capsid." Digital Archive @ GSU, 2008. http://digitalarchive.gsu.edu/biology_theses/18.

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As a model for studying apoptosis associated with pathogenesis of congenital rubella syndrome, bicistronic rubella virus (RUBV) replicons expressing an antibiotic resistance gene in the presence (925-IN) or absence (IN-IN) of RUBV capsid protein (C) were constructed. Apoptosis was assessed by detection of caspase activation, chromatin fragmentation, and flow cytometry. 925-IN cells grew similarly to Vero, but IN-IN cells demonstrated caspase activation, chromatin fragmentation and cell cycle arrest. Whereas Vero cells transfected with P150 exhibited rapid apoptosis not detected in transfected

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8

Richardson, J. Andrew. "Encapsidation studies with picornavirus subgenomic replicons." Thesis, University of Reading, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.284433.

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9

Semmler, Ilia. "Verpackte Replikons des Virus der Bovinene Virusdiarrhoe (BVDV) als neuartige Vakzine." Diss., lmu, 2005. http://nbn-resolving.de/urn:nbn:de:bvb:19-38143.

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10

Spiers, Andrew J. (Andrew Julian). "Molecular and genetic analysis of RepA from the P307 RepFIB replicon." Thesis, University of Auckland, 1992. http://hdl.handle.net/2292/2044.

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The work in this Thesis concerns the replication control system of the P307 plasmid RepFIB replicon. The basic replicon occupies ≈ 1.6kb of DNA and contains a single large open reading frame (repA) flanked on either side by a series DNA repeat elements. The organisational structure of fie replicon has placed RepFIB into the Step function class of replicons. The placement of RepFIB within this group, as well as a strong homology between RepFIB and mini-P1, has resulted in a series of predictions concerning the control elements of RepFIB replication. The aim of this work was to test some of thes

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11

Mohr, Hermine. "Cytomegalovirus replicon-based regulation of gene expression in vitro and in vivo." Diss., lmu, 2012. http://nbn-resolving.de/urn:nbn:de:bvb:19-150840.

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12

Thompson, Joseph Michael Johnston Robert E. "Venezuelan equine encephalitis virus replicon particles mucosal vaccine vectors and biological adjuvants /." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2007. http://dc.lib.unc.edu/u?/etd,1006.

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Thesis (Ph. D.)--University of North Carolina at Chapel Hill, 2007.<br>Title from electronic title page (viewed Dec. 18, 2007). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Microbiology and Immunology." Discipline: Microbiology and Immunology; Department/School: Medicine.

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13

Khan, Ayaz, and Muhammad Haidar Zaman. "Mutagenesis of a Dengue virus replicon by introducing stop codons within NS5." Thesis, Södertörns högskola, Institutionen för naturvetenskap, miljö och teknik, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:sh:diva-28645.

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Dengue Virus (DENV) is a positive single stranded RNA virus presented in four serotypes, DEN1V, DEN2V, DEN3V and DEN4V. Its structure is composed of three structural proteins, capsid, precursor membrane (prM) and envelope, and seven non structural (NS) proteins, NS1, NS2A, NS2B, NS3, NS4A, NS4B, and NS5. NS5 has a vital role in the replication of flavivirus. In this project, four different experimental procedures based on standard protocols, were used to create mutations in NS5 of DEN2V. There was no growth in original plates after overnight observation in experiment 1 and in experiment 2, com

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14

Kaido, Masanori. "The in vivo mRNA amplification system in transgenic plants expressing RNA replicon." Kyoto University, 1996. http://hdl.handle.net/2433/78075.

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Kyoto University (京都大学)<br>0048<br>新制・課程博士<br>博士(農学)<br>甲第6548号<br>農博第898号<br>新制||農||728(附属図書館)<br>学位論文||H8||N2959(農学部図書室)<br>UT51-96-T494<br>京都大学大学院農学研究科農林生物学専攻<br>(主査)教授古澤巖, 教授泉井桂, 教授津田盛也<br>学位規則第4条第1項該当

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15

Griffin, Sarah. "Optimisation of the mycobacterial replicon of an E. coli-mycobacterial shuttle vector." Master's thesis, University of Cape Town, 2007. http://hdl.handle.net/11427/2727.

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Includes bibliographical references (leaves 89-95).<br>This study aimed to investigate whether the mycobacterial replicon may also play a role. The common mycobacterial replicon in episomal E. coli-mycobacterial shuttle vectors contains the truncated rap gene, encoding an auxiliary replication factor, and the repA and repB genes which code for essential replication proteins. Specific aspects of this typical mycobacterial replicon were identified as potential targets to improve stability and increase recombinant protein expression levels, and were modified accordingly.

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16

Robida, John Matthew. "Characterization of hepatitis C virus subgenomic replicon resistance to cyclosporine in vitro." Tallahassee, Florida : Florida State University, 2009. http://etd.lib.fsu.edu/theses/available/etd-08212009-141751/.

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Thesis (M.S.)--Florida State University, 2009.<br>Advisor: Hengli Tang, Florida State University, College of Arts and Sciences, Dept. of Biological Science. Title and description from dissertation home page (viewed on Feb. 25, 2010). Document formatted into pages; contains vii, 31 pages. Includes bibliographical references.

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17

Colmenero, Paula. "Tumor gene therapy using Semliki forest virus replicons /." Stockholm : [Karolinska institutets bibl.], 2001. http://diss.kib.ki.se/2001/91-7349-044-X/.

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18

Yang, Joyce Chun-Yi. "Conjugation of extrachromosomal replicons of Rhodococcus erythropolis AN12." Thesis, Massachusetts Institute of Technology, 2006. http://hdl.handle.net/1721.1/34575.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 2006.<br>Includes bibliographical references.<br>Bacteria belonging to the Gram-positive actinomycete species, Rhodococcus erythropolis, are diverse not only in terms of metabolic potentials but the plasmids they encode. Pulsed-field gel electrophoresis (PFGE) revealed three previously uncharacterized megaplasmids in the genome of Rhodococcus erythropolis AN12. These megaplasmids, pREA400, pREA250 and pREA100, migrate at approximately 400 kb, 250 kb and 100 kb, respectively. Genetic screening of an AN12 transposon insert

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19

Datta, Shibani. "Isolation and genetic dissection of an eukaryotic replicon that supports autonomous DNA replication." Texas A&M University, 2005. http://hdl.handle.net/1969.1/4666.

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Maintenance of genome integrity requires that chromosomes be accurately and faithfully replicated. We are using Tetrahymena thermophila as a model system for studying the initiation and regulation of eukaryotic DNA replication. This organism contains a diploid micronucleus and polyploid macronucleus. During macronuclear development, the five diploid chromosomes of the micronucleus are fragmented into 280 macronuclear minichromosomes that are subsequently replicated to ~45 copies. In stark contrast, the 21 kb ribosomal DNA minichromosome (rDNA) is amplified from 2 to 10,000 copies in the same n

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20

Chakravarty, Leena. "Characterization of thepTFI91-family replicon and a novel insertion element of Thiobacillus ferrooxidans /." The Ohio State University, 1995. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487862972137376.

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21

Kishine, Hiroe. "Subgenomic replicon derived from a cell line infected with the hepatitis C virus." Kyoto University, 2002. http://hdl.handle.net/2433/149347.

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22

Narang, Ajoo Monica Carleton University Dissertation Biology. "Isolation and characterization of mutations affecting copy number control of the pCU1 replicon." Ottawa, 1990.

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23

Malykhina, Olga. "A Respiratory Syncytial Virus Replicon That Is Non-Cytotoxic and Capable of Long-Term Foreign Gene Expression." The Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1306863533.

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24

Zhang, Mingda. "Plant mitochondrial RNA : replicons characterization and developmentally regulated distribution." Thesis, McGill University, 1993. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=41804.

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The structure of one member of a family of maize mitochondrial RNA replicons (or RNA plasmids), RNA b, has been characterized. It is shown that RNA b shares a 13 nucleotide sequence with the central conserved region of Cadang-Cadang viroid of coconuts which might be involved in substrate recognition by the RNA replicase during replication. RNA b likely was derived from a larger member in that family, RNA a, through co-linear deletions similar to those involved with the generation of the defective interfering (DI) elements associated with both animal and plant viruses. RNA b may represent a "se

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25

Pluhař, Tomáš. "Návrh repliky letounu L-40 "Meta Sokol" - křídlo." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2008. http://www.nusl.cz/ntk/nusl-227918.

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This diploma thesis targets in concept of wing, aileron, flap and main undercarriage of the ultralight replication of the plane L-40 called Meta Sokol. The thesis developed from cooperation with two other members of the team – Alice Lipková (aerodynamics, power) and Miroslav Růžička (fuselage, tail unit and rear gear). The first part of this diploma thesis is concerned with load and concept of structure of the wing. At first the flight envelope is specified, then charakteristics of shearing force, bending moment and torsion moment are determined spanwise. The concept and subsequent strength ve

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26

Růžička, Miroslav. "Návrh repliky letounu L-40 "Meta Sokol" - trup." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2008. http://www.nusl.cz/ntk/nusl-227921.

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This diploma thesis deals with the design of all-metal construction of fuselage of the replica L-40 Meta Sokol aircraft on the basis of CS-VLA regulation. As far as the aircraft is concerned, the thesis establishes the load of tail surfaces, landing gear and engine bed. Futhermore, it designs the construction of fuselage, tail landing gear, including the system of its retraction, wing-fuselage connection, engine bed and the primary design of cockpit. In the end, the thesis focuses on the fuselage production technology.

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27

Dabert, Patrick. "Effet de la sequence chi sur les replicons cercle roulant." Paris 11, 1992. http://www.theses.fr/1992PA112158.

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L'insertion d'un fragment d'adn etranger dans un plasmide se repliquant par un mecanisme de cercle roulant (plasmide rcr) conduit frequemment a l'apparition de multimeres plasmidiques lineaires de haut poids moleculaire (hmw). Ce phenomene, qui semble particulier a ce type de replicons, s'observe dans de nombreuses especes bacteriennes gram-positives ou gram-negatives. Les travaux presentes ici concernent la caracterisation des facteurs intervenant dans la production de hmw chez escherichia coli. Ils indiquent que l'accumulation de hmw s'observe dans deux circonstances: (i) lorsqu'on etablit u

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28

Anraku, Itaru. "Induction of long lasting protective CD8+ T lymphocyte responses by Kunjin replicon-based vaccine vectors /." [St. Lucia, Qld.], 2005. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe18960.pdf.

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29

Henn, Alina [Verfasser]. "Evaluation der MDA-5 abhängigen Immunstimulation durch virale Replikons und enzymatisch hergestellte Polynukleotide / Alina Henn." Bonn : Universitäts- und Landesbibliothek Bonn, 2013. http://d-nb.info/1043699546/34.

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30

Marraiki, Najat A. Y. "Recombinant virus like particles comprising hepatitis C virus (HCV) structural proteins and HCV replicon RNA." Thesis, University of Leeds, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.422629.

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31

Permana, Paskasari A. "SV40 minichromosome: A mammalian replicon model for investigations of antineoplastic drugs and DNA damaging agents /." The Ohio State University, 1993. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487846885776862.

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32

Crome, Erhard. "Afghanistan – Ein Menetekel : Replik auf Sibylle Tönnies." Universität Potsdam, 2011. http://opus.kobv.de/ubp/volltexte/2013/6335/.

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33

Tulloch, Fiona. "Development of a foot-and-mouth disease virus replicon system for the study of RNA replication." Thesis, University of St Andrews, 2015. http://hdl.handle.net/10023/6858.

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Foot-and-mouth disease (FMD) is a highly infectious disease of wild and domestic cloven–hoofed animals such as cattle, swine and deer. It is caused by one of the most contagious animal diseases known; FMD virus (FMDV). Since the disease is endemic in many countries, transmission by international travel/trade presents an on-going potential threat to the UK. Very little is known at the molecular level about how FMDV replicates within host cells. In this study, FMDV replicons have been used to investigate FMDV RNA replication and to improve our understanding of the viral life cycle: a process whi

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34

Queiroz, Sabrina Ribeiro de Almeida. "Estratégias moleculares para utilização do vírus da febre amarela como vetor vacinal." Centro de Pesquisas Aggeu Magalhães, 2011. https://www.arca.fiocruz.br/handle/icict/10592.

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Made available in DSpace on 2015-06-01T19:28:08Z (GMT). No. of bitstreams: 2 501.pdf: 2806630 bytes, checksum: 5dbcbb44377fbc1620ff4879d96a08d9 (MD5) license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) Previous issue date: 2011<br>A vacina da febre amarela 17D (YFV-17D) é bastante segura e uma dose única confere imunidade potente e duradoura. Por essas e outras características, diferentes tecnologias têm sido propostas para a utilização da cepa 17D como vetor vacinal. Estratégias promissoras para o desenvolvimento de novas vacinas têm se baseado na construção de quimera

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35

Moran, Timothy P. Serody Jonathan S. Johnston Robert E. "Characterization of dendritic cells transduced with Venezuelan equine encephalitis virus replicon particles as therapeutic cancer vaccines." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2006. http://dc.lib.unc.edu/u?/etd,701.

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Thesis (Ph. D.)--University of North Carolina at Chapel Hill, 2006.<br>Title from electronic title page (viewed Oct. 10, 2007). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Microbiology and Immunology." Discipline: Microbiology and Immunology; Department/School: Medicine.

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36

McInerney, Gerald Michael. "Trans-encapsidation of capsid-defective foot-and-mouth disease virus replicons." Thesis, University of Reading, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.301929.

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37

Clifford, Timothy Burgess. "An investigation into the feasibility of virus-induced reverse-sense replicons." Thesis, University of Bristol, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.299593.

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38

Kiaupiene, Jurate. "Replik zu Marceli Kosmans Version der litauischen Geschichte." Universität Potsdam, 1997. http://opus.kobv.de/ubp/volltexte/2006/1130/.

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J. Kiaupiene, a severe critic of Kosman’s ideas, presents a different view on Lithuanian history. Kosman's description of Lithuania's past is neither exact nor new. Scholars in Russia, Poland and Belorussia have interpreted Lithuania's history in very different ways. The reason for this variety is the difference of national interests. Kosman's view reflects Polish messianism and cultural hybris. But even among Lithuanian scholars there are conflicting views on this nation's history and cultural identity.

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39

Lipková, Alica. "Návrh repliky letounu L-40 "Meta Sokol" - základní rozměry - technologie." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2008. http://www.nusl.cz/ntk/nusl-227920.

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The object of the diploma thesis is a preparation of fundamentals for realization for replica of the aircraft L-40 „Meta Sokol“ matching the requirements of Certification Specification for Very Light Aeroplanes (CS-VLA). The preamble of the work deals with the changes made on the original aircraft necessary to satisfy the criterias of the above-mentioned specification. One of the main contents of the first part of the thesis is the definition of replica’s basic dimensions and preparation of aerostatic fundamentals, including longitudinal stability control. As next a suitable engine is chosen a

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40

Mohr, Hermine [Verfasser], and Ulrich [Akademischer Betreuer] Koszinowski. "Cytomegalovirus replicon-based regulation of gene expression in vitro and in vivo / Hermine Mohr. Betreuer: Ulrich Koszinowski." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2012. http://d-nb.info/1029040389/34.

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41

DELIAT, FABIENNE. "Etude fonctionnelle de la replication du poliovirus au moyen de replicons bicistroniques." Paris 7, 1998. http://www.theses.fr/1998PA077201.

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Le poliovirus (pv), responsable de la poliomyelite, est le virus modele de la famille des picornaviridae. Le genome est un arn simple brin positif, traduit en une polyproteine unique dont la synthese est initiee a partir d'une sequence ires (segment d'entree interne des ribosomes). La polyproteine, decoupee par les proteases virales neosynthetisees, genere des precurseurs intermediaires puis les proteines matures. La region p1 correspond aux proteines de capside et les regions p2 et p3 aux proteines non structurales, impliquees dans la replication de l'arn. Afin de determiner si les proteines

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42

Meyerhöfer, Wolfram. "Erkennen und Vorurteil : Antwort auf die Replik von Iffert." Universität Potsdam, 2006. http://opus.kobv.de/ubp/volltexte/2008/2198/.

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43

Mehring, Reinhard. "Keine einfachen Alternativen und Lösungen! : Replik auf Sibylle Tönnies." Universität Potsdam, 2011. http://opus.kobv.de/ubp/volltexte/2013/6333/.

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44

Korf, Mortimer. "Inhibition der Replikation und Translation eines subgenomischen Hepatitis-C-Virus-Replikons durch HCV-RNA- und Kofaktor-gerichtete Strategien." [S.l. : s.n.], 2005. http://deposit.ddb.de/cgi-bin/dokserv?idn=976146193.

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45

Webb, Drue Laine White Laura J. "Development of improved dengue 2 antigen configurations for a Venezuelan equine encephalitis virus replicon particle-launched dengue vaccine." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2008. http://dc.lib.unc.edu/u?/etd,1498.

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Thesis (M.S.)--University of North Carolina at Chapel Hill, 2008.<br>Title from electronic title page (viewed Sep. 16, 2008). "... in partial fulfillment of the requirements for the degree of Master of Science in the Department of Microbiology and Immunology." Discipline: Microbiology and Immunology; Department/School: Medicine.

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46

Krishnan, B. Rajendra Carleton University Dissertation Biology. "The incN antibiotic-resistance plasmid pCU1: bacterial host-range, nucleotide sequence, deletion and subcloning analysis of the replicon." Ottawa, 1989.

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47

Nelson, Heather Babb. "Selection and characterization of HCV replicon cells that are resistant to cyclosporine A and temperature shift in vitro." Tallahassee, Florida : Florida State University, 2009. http://etd.lib.fsu.edu/theses/available/etd-08102009-210344/.

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Thesis (M.S.)--Florida State University, 2009.<br>Advisor: Hengli Tang, Florida State University, College of Arts and Sciences, Dept. of Biological Science. Title and description from dissertation home page (viewed on Feb. 24, 2010). Document formatted into pages; contains x, 42 pages. Includes bibliographical references.

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48

Gardner, Murray Newell. "An investigation into the replicon of a broad host range mobilizable plasmid from the moderately thermophilic bacterium Acidithiobacillus caldus." Thesis, Stellenbosch : Stellenbosch University, 2003. http://hdl.handle.net/10019.1/53273.

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Dissertation (PhD)--University of Stellenbosch, 2003.<br>ENGLISH ABSTRACT: The moderately thermophilic (45 to 50DC), highly acidophilic (pH 1.5 to 2.5), chemolithoautotrophic Acidithiobaci/lus caldus strain "f' was isolated from a biooxidation process used to treat nickel ore concentrates. Trans-Alternating Field Electrophoresis (TAFE) analysis of total DNA from the At. caldus cells revealed two plasmids of approximately 14 and 45-kb. The 14-kb plasmid, designated pTC-F14, was cloned and shown by replacement of the cloning vector with a kanamycin resistance gene to be capable of autonom

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49

Bezděk, Adam. "Uplatnění technologie "reverse engineering" při zhotovení repliky Al odlitku metodou vytavitelného modelu." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2016. http://www.nusl.cz/ntk/nusl-241910.

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The aim of this thesis was to produce a prototype casting of aluminum alloy with usage of reverse engineering technology. In a production process surface quality and dimensional accuracy was optimized. 3D scanning, FDM technology, ABSplus surface finishing possibilities and investment casting technology is introduced in theoretical part of this thesis. Practical part of the thesis includes description of original parts, their 3D scanning, usage of RE and RP, production of new castings and evaluation of their dimensional accuracy and surface roughness.

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Gießmann, Hans J. "Ein Plädoyer für das moderne Völkerrecht : Replik auf Sibylle Tönnies." Universität Potsdam, 2011. http://opus.kobv.de/ubp/volltexte/2013/6336/.

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