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1

IVANKOVICH, ANTHONY D. "Asymptomatic Hyponatremia Does Not Require Rapid Correction." Anesthesiology 72, no. 2 (1990): 397. http://dx.doi.org/10.1097/00000542-199002000-00039.

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2

VAN BOVEN, MICHEL J. "Asymptomatic Hyponatremia Does Not Require Rapid Correction." Anesthesiology 72, no. 2 (1990): 397. http://dx.doi.org/10.1097/00000542-199002000-00040.

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3

Kuznar, W., J. L. Saver, A. H. Tilton, N. B. Fountain, and L. Gutmann. "Neurologic Emergencies Require Rapid Plan of Action." MD Conference Express 15, no. 9 (2015): 20–22. http://dx.doi.org/10.1177/1559897715588494.

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4

Dinnes, Jacqueline. "COVID-19 rapid antigen testing strategies require careful evaluation." EBioMedicine 70 (August 2021): 103491. http://dx.doi.org/10.1016/j.ebiom.2021.103491.

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Lagomarsino, Laura P. "Rapid plant diversification in the Andes does not require flowers." New Phytologist 222, no. 1 (2019): 11–13. http://dx.doi.org/10.1111/nph.15619.

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Ilin, V., A. Malyshev, F. Wolf, and M. Volgushev. "Fast Computations in Cortical Ensembles Require Rapid Initiation of Action Potentials." Journal of Neuroscience 33, no. 6 (2013): 2281–92. http://dx.doi.org/10.1523/jneurosci.0771-12.2013.

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7

Leib, David E., and Zachary A. Knight. "Rapid Sensing of Dietary Amino Acid Deficiency Does Not Require GCN2." Cell Reports 16, no. 8 (2016): 2051–52. http://dx.doi.org/10.1016/j.celrep.2016.08.022.

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8

Akrap, Gordan. "Hybrid Challenges Require Hybrid, Scientifically Based, Responses." National security and the future 20, no. 1-2 (2020): 25–33. http://dx.doi.org/10.37458/nstf.20.1-2.4.

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New security challenges are looking for new security paradigms in order that state and societies can successfully face with them on preventive level. Due to the rapid influence of hybrid threats to almost all areas of our lives today, we must change our attitude toward those problems and introduce and transform existing intelligence and security studies as a separate science in order to prepare our societies for security challenges that are already here.
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9

Chowienczyk, S., A. Rose, H. Calderwood, T. Wright, and A. Hinton. "32IMPROVING THE CARE OF PATIENTS WHO REQUIRE RAPID TRANQUILISATION: A CLINICAL AUDIT." Age and Ageing 48, Supplement_1 (2019): i1—i15. http://dx.doi.org/10.1093/ageing/afy211.32.

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Asp, Lennart, Fredrik Kartberg, Julia Fernandez-Rodriguez, et al. "Early Stages of Golgi Vesicle and Tubule Formation Require Diacylglycerol." Molecular Biology of the Cell 20, no. 3 (2009): 780–90. http://dx.doi.org/10.1091/mbc.e08-03-0256.

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We have investigated the role for diacylglycerol (DAG) in membrane bud formation in the Golgi apparatus. Addition of propranolol to specifically inhibit phosphatidate phosphohydrolase (PAP), an enzyme responsible for converting phosphatidic acid into DAG, effectively prevents formation of membrane buds. The effect of PAP inhibition on Golgi membranes is rapid and occurs within 3 min. Removal of the PAP inhibitor then results in a rapid burst of buds, vesicles, and tubules that peaks within 2 min. The inability to form buds in the presence of propranolol does not appear to be correlated with a
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11

Ataman, Bulent, James Ashley, Michael Gorczyca, et al. "Rapid Activity-Dependent Modifications in Synaptic Structure and Function Require Bidirectional Wnt Signaling." Neuron 57, no. 5 (2008): 705–18. http://dx.doi.org/10.1016/j.neuron.2008.01.026.

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Odofin, O., R. Alexander, H. Bowers, H. Chave, and G. Branagan. "Do patients require outpatient follow-up after rapid referral double contrast barium enema?" Colorectal Disease 11, no. 7 (2009): 729–32. http://dx.doi.org/10.1111/j.1463-1318.2008.01605.x.

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13

B. Moss, Ronald, Meghan McCabe Pryor, Rebecca Baillie, et al. "Brief Report: Higher Fentanyl Exposures Require Higher Doses of Naloxone for Successful Reversals in a Quantitative Systems Pharmacology Model." Addiction Research and Adolescent Behaviour 5, no. 2 (2022): 01–05. http://dx.doi.org/10.31579/2688-7517/034.

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Background: Previously, we reported on an opioid receptor quantitative systems pharmacology (QSP) model to evaluate naloxone Methods: In this study, we extended our model to include higher systemic levels of fentanyl (up to 100 ng/ml) and the newly approved 8mg IN naloxone dose (equivalent to 4 mg) Results: As expected, at the lower peak fentanyl concentrations (25 ng/ml and 50 ng/ml), the simulations predicted that 2 mg, 4 mg, 5 mg, and 10 mg IM doses of naloxone displaced fentanyl and reached below the 50% receptor occupancy within 10 minutes. However, at the concentration of 75 ng/ml, the s
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14

Gimenez, Tyler L., Maja Lorenc, and Santiago Jaramillo. "Adaptive categorization of sound frequency does not require the auditory cortex in rats." Journal of Neurophysiology 114, no. 2 (2015): 1137–45. http://dx.doi.org/10.1152/jn.00124.2015.

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A defining feature of adaptive behavior is our ability to change the way we interpret sensory stimuli depending on context. Rapid adaptation in behavior has been attributed to frontal cortical circuits, but it is not clear if sensory cortexes also play an essential role in such tasks. In this study we tested whether the auditory cortex was necessary for rapid adaptation in the interpretation of sounds. We used a two-alternative choice sound-categorization task for rats in which the boundary that separated two acoustic categories changed several times within a behavioral session. These shifts i
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15

Morillon, Raphaël, David Liénard, Maarten J. Chrispeels, and Jean-Paul Lassalles. "Rapid Movements of Plants Organs Require Solute-Water Cotransporters or Contractile Proteins: Fig. 1." Plant Physiology 127, no. 3 (2001): 720–23. http://dx.doi.org/10.1104/pp.010732.

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16

Aschenbrenner, Laura, Samia N. Naccache, and Tama Hasson. "Uncoated Endocytic Vesicles Require the Unconventional Myosin, Myo6, for Rapid Transport through Actin Barriers." Molecular Biology of the Cell 15, no. 5 (2004): 2253–63. http://dx.doi.org/10.1091/mbc.e04-01-0002.

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After clathrin-mediated endocytosis, clathrin removal yields an uncoated vesicle population primed for fusion with the early endosome. Here we present the first characterization of uncoated vesicles and show that myo6, an unconventional myosin, functions to move these vesicles out of actin-rich regions found in epithelial cells. Time-lapse microscopy revealed that myo6-associated uncoated vesicles were motile and exhibited fusion and stretching events before endosome delivery, processes that were dependent on myo6 motor activity. In the absence of myo6 motor activity, uncoated vesicles remaine
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17

Shin, Seokyung, Dong Woo Han, Hye Sun Lee, Mi Kyung Song, Eun-kyung Jun, and So Yeon Kim. "Elderly Patients Require Higher Doses of Sugammadex for Rapid Recovery from Deep Neuromuscular Block." Basic & Clinical Pharmacology & Toxicology 118, no. 6 (2015): 462–67. http://dx.doi.org/10.1111/bcpt.12507.

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18

Watson, Fiona L., Heather M. Heerssen, Daniel B. Moheban, et al. "Rapid Nuclear Responses to Target-Derived Neurotrophins Require Retrograde Transport of Ligand–Receptor Complex." Journal of Neuroscience 19, no. 18 (1999): 7889–900. http://dx.doi.org/10.1523/jneurosci.19-18-07889.1999.

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19

Nimmo, Graeme R. "Rapid detection of bacteraemia." Microbiology Australia 31, no. 3 (2010): 131. http://dx.doi.org/10.1071/ma10131.

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Bacteraemic sepsis has a high mortality that can be reduced by early diagnosis and initiation of appropriate antimicrobial therapy 1. Rapid confirmation of the diagnosis and identification of the causal agent provide guidance on the adequacy and duration of antimicrobial therapy and on the need for source investigation. Clinical microbiology laboratories have rightly placed great emphasis on this aspect of their practice. As causal organisms are usually present in low titre, direct microscopy is impractical and laboratories have generally relied on culture of blood in broth, which is relativel
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20

Bauer, S. J. "Succinylcholine induced masseter spasm during rapid sequence intubation may require a surgical airway: case report." Emergency Medicine Journal 22, no. 6 (2005): 456–58. http://dx.doi.org/10.1136/emj.2004.014571.

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21

Duguid, John, and Paul Friedman. "Pandemic-related supply chain disruptions in cell therapy require rapid qualification for single-sourced materials." Cell and Gene Therapy Insights 8, no. 2 (2022): 257–60. http://dx.doi.org/10.18609/cgti.2022.042.

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22

Laird-Offringa, Ite A., Peter Elfferich, and A. J. van der Eb. "Rapidc-mycmRNA degradation does not require (A + U)-rich sequences or complete translation of the mRNA." Nucleic Acids Research 19, no. 9 (1991): 2387–94. http://dx.doi.org/10.1093/nar/19.9.2387.

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23

Li, Lihong, Shawna Miles, Zephan Melville, Amalthiya Prasad, Graham Bradley, and Linda L. Breeden. "Key events during the transition from rapid growth to quiescence in budding yeast require posttranscriptional regulators." Molecular Biology of the Cell 24, no. 23 (2013): 3697–709. http://dx.doi.org/10.1091/mbc.e13-05-0241.

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Yeast that naturally exhaust the glucose from their environment differentiate into three distinct cell types distinguishable by flow cytometry. Among these is a quiescent (Q) population, which is so named because of its uniform but readily reversed G1 arrest, its fortified cell walls, heat tolerance, and longevity. Daughter cells predominate in Q-cell populations and are the longest lived. The events that differentiate Q cells from nonquiescent (nonQ) cells are initiated within hours of the diauxic shift, when cells have scavenged all the glucose from the media. These include highly asymmetric
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24

Bak, G., E. J. Lee, Y. Lee, et al. "Rapid Structural Changes and Acidification of Guard Cell Vacuoles during Stomatal Closure Require Phosphatidylinositol 3,5-Bisphosphate." Plant Cell 25, no. 6 (2013): 2202–16. http://dx.doi.org/10.1105/tpc.113.110411.

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25

Atif, Shaikh M., Seung‐Joo Lee, Lin‐Xi Li, et al. "Rapid CD4 + T‐cell responses to bacterial flagellin require dendritic cell expression of Syk and CARD9." European Journal of Immunology 45, no. 2 (2014): 513–24. http://dx.doi.org/10.1002/eji.201444744.

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26

Kavlak, Goksin, James McNerney, Robert L. Jaffe, and Jessika E. Trancik. "Metal production requirements for rapid photovoltaics deployment." Energy & Environmental Science 8, no. 6 (2015): 1651–59. http://dx.doi.org/10.1039/c5ee00585j.

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To supply even a small share of electricity in 2030, several thin-film photovoltaic (PV) technologies, such as CdTe shown here, would require metal production growth rates that exceed those observed historically. In contrast, crystalline silicon could supply a majority electricity share without requiring unprecedented metal growth rates.
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27

Rosqvist, Gunhild C., Niila Inga, and Pia Eriksson. "Impacts of climate warming on reindeer herding require new land-use strategies." Ambio 51, no. 5 (2021): 1247–62. http://dx.doi.org/10.1007/s13280-021-01655-2.

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AbstractClimate in the Arctic has warmed at a more rapid pace than the global average over the past few decades leading to weather, snow, and ice situations previously unencountered. Reindeer herding is one of the primary livelihoods for Indigenous peoples throughout the Arctic. To understand how the new climate state forces societal adaptation, including new management strategies and needs for preserved, interconnected, undisturbed grazing areas, we coupled changes in temperature, precipitation, and snow depth recorded by automatic weather stations to herder observations of reindeer behaviour
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28

Levi, M. H., P. Gialanella, M. R. Motyl, and J. C. McKitrick. "Rapid detection of positive blood cultures with the BACTEC NR-660 does not require first-day subculturing." Journal of Clinical Microbiology 26, no. 11 (1988): 2262–65. http://dx.doi.org/10.1128/jcm.26.11.2262-2265.1988.

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29

SWANSON, M., H. BARKER, and S. A. MACFARLANE. "Rapid vascular movement of tobraviruses does not require coat protein: evidence from mutated and wild-type viruses." Annals of Applied Biology 141, no. 3 (2002): 259–66. http://dx.doi.org/10.1111/j.1744-7348.2002.tb00217.x.

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30

Yu, Kenneth C.-W., Yuan Jiang, Wei Chen, and Allen D. Cooper. "Rapid initial removal of chylomicron remnants by the mouse liver does not require hepatically localized apolipoprotein E." Journal of Lipid Research 41, no. 11 (2000): 1715–27. http://dx.doi.org/10.1016/s0022-2275(20)31965-9.

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31

Killard, A. J., M. R. Smyth, K. Grennan, L. Micheli, and G. Palleschi. "Rapid antibody biosensor assays for environmental analysis." Biochemical Society Transactions 28, no. 2 (2000): 81–84. http://dx.doi.org/10.1042/bst0280081.

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Traditionally, biosensor development has focused on molecules with a defined metabolic role that can be exploited by enzyme-based systems. Antibodies have the ability to move beyond this range of analytes, and are particularly useful in detecting small, hapten molecules. Electrochemically based biosensor developments have been less fruitful in this regard, as enzyme labelling is required, and such assays require the separation from bound and unbound species. These separations and the removal of background signals result in the increased complexity of the assay format, making it unsuitable for
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32

Md. Sharif, Shakirah, Wuan Shuen Yap, Weng Hong Fun, et al. "Midwifery Qualification in Selected Countries: A Rapid Review." Nursing Reports 11, no. 4 (2021): 859–80. http://dx.doi.org/10.3390/nursrep11040080.

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Background: While the global maternal mortality ratio (MMR) shows a decreasing trend, there is room for improvement. Midwifery education has been under scrutiny to ensure that graduates acquire knowledge and skills relevant to the local context. Objective: To review the basic professional midwifery qualification and pre-practice requirements in countries with lower MMR compared with Malaysia. Methods: A rapid review of country-specific Ministry of Health and Midwifery Association websites and Advanced Google using standardised key words. English-language documents reporting the qualifications
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33

Li, Xingguo, Shaohua Wang, Ying Li, et al. "Chromatin boundaries require functional collaboration between the hSET1 and NURF complexes." Blood 118, no. 5 (2011): 1386–94. http://dx.doi.org/10.1182/blood-2010-11-319111.

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Abstract Chromatin insulators protect erythroid genes from being silenced during erythropoiesis, and the disruption of barrier insulator function in erythroid membrane gene loci results in mild or severe anemia. We showed previously that the USF1/2-bound 5′HS4 insulator mediates chromatin barrier activity in the erythroid-specific chicken β-globin locus. It is currently not known how insulators establish such a barrier. To understand the function of USF1, we purified USF1-associated protein complexes and found that USF1 forms a multiprotein complex with hSET1 and NURF, thus exhibiting histone
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Borisyak, Maxim, Tatiana Gaintseva, and Andrey Ustyuzhanin. "Adaptive divergence for rapid adversarial optimization." PeerJ Computer Science 6 (May 18, 2020): e274. http://dx.doi.org/10.7717/peerj-cs.274.

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Adversarial Optimization provides a reliable, practical way to match two implicitly defined distributions, one of which is typically represented by a sample of real data, and the other is represented by a parameterized generator. Matching of the distributions is achieved by minimizing a divergence between these distribution, and estimation of the divergence involves a secondary optimization task, which, typically, requires training a model to discriminate between these distributions. The choice of the model has its trade-off: high-capacity models provide good estimations of the divergence, but
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35

Noronen, K., E. Saarinen, A. Albäck, and M. Venermo. "Analysis of the Elective Treatment Process for Critical Limb Ischaemia with Tissue Loss: Diabetic Patients Require Rapid Revascularisation." Journal of Vascular Surgery 65, no. 3 (2017): 927–28. http://dx.doi.org/10.1016/j.jvs.2017.01.005.

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36

da Silva Teixeira, Silvania, Keisha Harrison, Munachismo Uzodike, et al. "Vitamin D actions in neurons require the PI3K pathway for both enhancing insulin signaling and rapid depolarizing effects." Journal of Steroid Biochemistry and Molecular Biology 200 (June 2020): 105690. http://dx.doi.org/10.1016/j.jsbmb.2020.105690.

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37

Lopez-Hernandez, F. J., M. A. Ortiz, Y. Bayon, and F. J. Piedrafita. "Retinoid-related molecules require caspase 9 for the effective release of Smac and the rapid induction of apoptosis." Cell Death & Differentiation 11, no. 2 (2003): 154–64. http://dx.doi.org/10.1038/sj.cdd.4401329.

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38

Noronen, K., E. Saarinen, A. Albäck, and M. Venermo. "Analysis of the Elective Treatment Process for Critical Limb Ischaemia with Tissue Loss: Diabetic Patients Require Rapid Revascularisation." European Journal of Vascular and Endovascular Surgery 53, no. 2 (2017): 206–13. http://dx.doi.org/10.1016/j.ejvs.2016.10.023.

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39

Heusel, Jonathan W., Robin L. Wesselschmidt, Sujan Shresta, John H. Russell, and Timothy J. Ley. "Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells." Cell 76, no. 6 (1994): 977–87. http://dx.doi.org/10.1016/0092-8674(94)90376-x.

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40

Akbar, Son Ali, Kawarul Hawari Ghazali, Habsah Hasan, Zeehaida Mohamed, Wahyu Sapto Aji, and Anton Yudhana. "Rapid bacterial colony classification using deep learning." Indonesian Journal of Electrical Engineering and Computer Science 26, no. 1 (2022): 352. http://dx.doi.org/10.11591/ijeecs.v26.i1.pp352-361.

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Bacterial colonies infection is one of the causes of bloodstream disease, and it can be a fatality. Therefore, medical diagnoses require fast identification and classification of organisms. Artificial Intelligence with deep learning (DL) can now be developed as a rapid bacterial classification. The research aims to combine deep learning and support vector machines (SVM). The ResNet-101 model of the DL algorithm extracted the image’s features using transfer learning then classified by the SVM classifier. According to the experimental results, this model had 99.61% accuracy, 99.58% recall, 99.58
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McCord, D. C., S. K. Kennedy, and D. G. Kritikos. "Rapid Manual SEM Analysis and the Greening of Digital Data." Microscopy and Microanalysis 3, S2 (1997): 1109–10. http://dx.doi.org/10.1017/s1431927600012435.

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Manual scanning electron microscope (SEM) analysis is historically considered to be slow and tedious resulting in a low volume of data. This is due in large part to the mechanics of moving stage locations and recording image and spectral data. Conversely, high volume data acquired using automated SEM analysis has been associated with the need for complex systems for data management and analysis. In addition, the proliferation of high volume digital microscopy and its attendant “ tonnage” of paper images has lead to the desire for a “green” (filmless and hardcopy-reduced) operation.There are so
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42

Giammara, B., W. DeVries, R. Baker, J. Dobbins, and J. Hanker. "Hexamethyldisilazane drying for rapid detection of bacteria in implant specimens." Proceedings, annual meeting, Electron Microscopy Society of America 45 (August 1987): 878–79. http://dx.doi.org/10.1017/s0424820100128675.

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Detection of bacteria in implants can be time consuming and equivocal. Routine histology of biopsy specimens from implant sites requires approximately 24 hours and is frequently indecisive for the demonstration of bacteria. Culture requires a minimum of 24-48 hours and may require repetitive cultures or subcultures which result in inhibition of the growth of commensals as well as conditions which favor the growth of suspected pathogens. Direct examination of implant specimens with the scanning electron microscope can show bacteria but the time, special equipment, and hazards associated with pr
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43

Liang, Pengbo, Thomas F. Stratil, Claudia Popp, et al. "Symbiotic root infections in Medicago truncatula require remorin-mediated receptor stabilization in membrane nanodomains." Proceedings of the National Academy of Sciences 115, no. 20 (2018): 5289–94. http://dx.doi.org/10.1073/pnas.1721868115.

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Plant cell infection is tightly controlled by cell surface receptor-like kinases (RLKs). Like other RLKs, the Medicago truncatula entry receptor LYK3 laterally segregates into membrane nanodomains in a stimulus-dependent manner. Although nanodomain localization arises as a generic feature of plant membrane proteins, the molecular mechanisms underlying such dynamic transitions and their functional relevance have remained poorly understood. Here we demonstrate that actin and the flotillin protein FLOT4 form the primary and indispensable core of a specific nanodomain. Infection-dependent inductio
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44

Li, Xingguo, Shaohua Wang, Ying Li, Yi Qiu, and Suming Huang. "Chromatin Boundaries Require the Functional Cooperation Between hSET1 and NURF Complexes." Blood 116, no. 21 (2010): 646. http://dx.doi.org/10.1182/blood.v116.21.646.646.

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Abstract Abstract 646 Chromatin modification and remodeling activities play a central role in organizing nuclear functions in eukaryotic genome. Chromatin domains with characteristic epigenetic marks are organized by chromatin insulator. The chicken b-globin insulator, 5′HS4, is an excellent model system to study how insulator maintains gene function and prevents the encroachment of repressive heterochromatin. We showed previously that USF1/2 bound 5′HS4 insulator mediates chromatin barrier activity by recruiting and organizing active histone modifications in the chicken b-globin locus. Howeve
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Jackson, Brenda, Joanne McPeake, and Bridget Johnston. "What information and resources do carers require pre and post bereavement in the acute hospital setting? A rapid review." Current Opinion in Supportive and Palliative Care 13, no. 4 (2019): 328–36. http://dx.doi.org/10.1097/spc.0000000000000462.

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46

Kang, Yuan Yuan, Yusuke Wachi, Elizabeth Engdorf, et al. "Normal Ethanol Sensitivity and Rapid Tolerance Require the G Protein Receptor Kinase 2 in Ellipsoid Body Neurons in Drosophila." Alcoholism: Clinical and Experimental Research 44, no. 8 (2020): 1686–99. http://dx.doi.org/10.1111/acer.14396.

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47

Lefroy, R., R. Morgan, and S. Rajagopalan. "Re “Analysis of the Elective Treatment Process for Critical Limb Ischaemia with Tissue Loss: Diabetic Patients Require Rapid Revascularisation”." European Journal of Vascular and Endovascular Surgery 53, no. 5 (2017): 755. http://dx.doi.org/10.1016/j.ejvs.2017.02.030.

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48

Kuruvilla, J., A. P. Farinha, N. Bayat, and S. Cristobal. "Surface proteomics on nanoparticles: a step to simplify the rapid prototyping of nanoparticles." Nanoscale Horizons 2, no. 1 (2017): 55–64. http://dx.doi.org/10.1039/c6nh00162a.

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49

Cho, Andrew, Shigeki Suzuki, Junko Hatakeyama, Naoto Haruyama, and Ashok B. Kulkarni. "A Method for Rapid Demineralization of Teeth and Bones." Open Dentistry Journal 4, no. 1 (2010): 223–29. http://dx.doi.org/10.2174/1874210601004010223.

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Tooth and bone specimen require extensive demineralization for careful analysis of cell morphology, as well as gene and protein expression levels. The LacZ gene, which encodes the ß-galactosidase enzyme, is often used as a reporter gene to study gene-structure function, tissue-specific expression by a promoter, cell lineage and fate. This reporter gene is particularly useful for analyzing the spatial and temporal gene expression pattern, by expressing the LacZ gene under the control of a promoter of interest. To analyze LacZ activity, and the expression of other genes and their protein product
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King, Neville J., and Thomas H. Ollendick. "School Refusal: Graduated and Rapid Behavioural Treatment Strategies." Australian & New Zealand Journal of Psychiatry 23, no. 2 (1989): 213–23. http://dx.doi.org/10.3109/00048678909062138.

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School refusal is a complex phenomenon that has been subject to definitional and diagnostic confusion. The aetiology of school refusal remains incompletely understood; heterogeneity rather than homogeneity prevails. In the behaviour management of school refusal, the clinician may plan either a gradual or rapid school return. Although a graduated return to school may be necessary in certain cases, secondary complications are minimized by an immediate return to school. Both graduated and rapid treatment require a flexible and integrative approach drawing on classical, operant and vicarious condi
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