Relevant bibliographies by topics / Residual monomers

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'Residual monomers'

Author: Grafiati
Published: 4 June 2021
Last updated: 13 February 2022

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Journal articles on the topic "Residual monomers"

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Suhono, Rosa Sharon, Endang Wahyuningtyas, and Titik Ismiyati. "Silica coating application on heat-cured acrylic resin plates towards the surface hardness and the amount of residual monomers." Padjadjaran Journal of Dentistry 31, no. 2 (2019): 123. http://dx.doi.org/10.24198/pjd.vol31no2.19310.

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Introduction: Silica has been used as a coating material on acrylic resin denture plates to reduce the attachment of C. albicans, and acrylic resin denture coating application has been shown to increase the resistance. Acrylic resin as denture plate has many advantages, including good aesthetical aspect, easy to be manipulated, and relatively low costs. Acrylic resin also has disadvantages, namely the presence of residual monomers, low abrasion resistance, and broken easily. Residual monomers have poor biocompatibility and can weaken the mechanical strength of acrylic resin dentures. The purpo
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Archegas, Lucí Regina Panka, Rodrigo Nunes Rached, Sérgio Aparecido Ignacio, Eliane Carvalho de Vasconcelos, Débora Toledo Ramos, and Evelise Machado de Souza. "Identification and quantification of monomers released from dental composites using HPLC." Brazilian Archives of Biology and Technology 52, no. 4 (2009): 855–62. http://dx.doi.org/10.1590/s1516-89132009000400009.

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The aim of this study was to detect and quantify the main residual monomers released from composites, using high performance liquid chromatography (HPLC). Discs were made with dental composites (Herculite XRV, Tetric Ceram and Filtek Z250) and immersed in deionized water at 37ºC for 28 days, with water changes in 1, 7, 14 and 21 days. The mean concentration of residual monomers were subject to the Kruskal-Wallis test (p<0.05). Tetric Ceram exhibited significantly higher concentrations of leached monomers. Bis-GMA was the monomer released in lower concentrations for all the materials. There
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Sonkaya, Ezgi, Zeliha Gonca Bek Kürklü, and Şeyhmus Bakır. "Effect of Polymerization Time on Residual Monomer Release in Dental Composite: In Vitro Study." International Journal of Polymer Science 2021 (August 21, 2021): 1–8. http://dx.doi.org/10.1155/2021/8101075.

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Light activated resin-based composites are the most accepted and used materials among clinicians. The aim of this study is to determine the amount of residual monomer released from nanofiller composite resins for different polymerization times and storage periods in vitro. To this purpose, Tetric Ceram (Ivoclar, Liechtenstein), Clearfil Majesty Posterior (Kuraray, Japan), Grandio (VOCO, Germany), and Filtek Ultimate Universal (3M, USA) were used as nanofiller resin composites samples. Four groups ( n = 40 , diameter: 5 mm, thickness: 2 mm) of each material were fabricated, and each group was e
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Rosha, Jayanti, Adioro Soetojo, Putu Dewi Purnama Sari Budha, and M. Mudjiono. "The effect of UDMA and Bis-GMA irradiation period on residual monomers in resin packable composite." Dental Journal (Majalah Kedokteran Gigi) 52, no. 1 (2019): 24. http://dx.doi.org/10.20473/j.djmkg.v52.i1.p24-26.

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Background: Residual monomers are non-polymerized monomers which can cause clinical harm, for example inflammation, to oral cavity tissue while the remaining monomers can potentially be carcinogenic. The more residual monomers that remain due to an imperfect polymerization processes, the lower the compressive strength level and the higher the number of micro slits that can cause secondary caries and tooth sensitivity. Urethane dimethacrylate (UDMA) and bisphenol A glycol dimethacrylate (Bis-GMA) constitute two of the resins most frequently used in packable composites. During the short irradiat
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Sanglar, C., M. Defay, H. Waton, et al. "Commercial Dental Composite: Determination of Reaction Advancement and Study of the Migration of Organic Compounds." Polymers and Polymer Composites 13, no. 3 (2005): 223–34. http://dx.doi.org/10.1177/096739110501300302.

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This work on organic dental composites was undertaken to determine the role of residual reactive methacrylate functions at the end of the photopolymerization cycle, and to investigate the fate of the residual monomers and oligomers in organic (ethanol) and aqueous (water and artificial saliva) media. The results show that all the methacrylate monomers present in dentine migrate into ethanol (about 1% (w/w)). In aqueous media on the other hand, only the most hydrophilic monomer (UDMA) migrates (0.05% (w/w)) into water and 0.03% into artificial saliva (pH = 9). This desorption in the three media
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Khan, Sarfaraz, Huaili Zheng, Qiang Sun, et al. "Analysis of Influencing Factors for Leaching of Acrylamide Monomer from Polyacrylamide-Based Flocculants Used in the Treatment of Sludge Dewatering." Sensor Letters 18, no. 2 (2020): 128–32. http://dx.doi.org/10.1166/sl.2020.4194.

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Acrylamide (AM) monomer is one of the harmful type substance, are commonly using to produce polyacrylamide (PAMs) flocculants for water treatment. Because of incomplete polymerization, the molecules of AM monomers also in exit marketable polymers. Therefore, discharge of AM from the usage of PAM based polymers flocculants in to environment. Currently study focus on, the AM leaching behaviour (emulsion and powder) polymer produced by two different production processes was studied with WTP sludge dewatering as the research object. The flocculants type's effects, Concentration of sludge and dosag
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Bezgin, Tugba, Ceren Cimen, and Nurhan Ozalp. "Evaluation of Residual Monomers Eluted from Pediatric Dental Restorative Materials." BioMed Research International 2021 (September 16, 2021): 1–8. http://dx.doi.org/10.1155/2021/6316171.

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Unreacted monomers eluted from resin-based restorative materials have been considered a reason of local and systemic adverse reactions. This study was designed to determine the effect of finishing and polishing procedures on the elution of Bis-GMA, TEGDMA, UDMA, and HEMA monomers from compomer and bulk-fill composite resins. Bulk-fill composite (3M ESPE GmbH, Seefeld, Germany) and compomer (Dentsply DeTrey GmbH, Konstanz, Germany) specimens with 3 × 4 mm diameters were prepared. The specimens were randomly divided into two groups, and finishing-polishing procedures were applied only to the exp
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Floros, Michael C., Alcides Lopes Leão, and Suresh S. Narine. "Vegetable Oil Derived Solvent, and Catalyst Free “Click Chemistry” Thermoplastic Polytriazoles." BioMed Research International 2014 (2014): 1–14. http://dx.doi.org/10.1155/2014/792901.

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Azide-alkyne Huisgen “click” chemistry provides new synthetic routes for making thermoplastic polytriazole polymers—without solvent or catalyst. This method was used to polymerize three diester dialkyne monomers with a lipid derived 18 carbon diazide to produce a series of polymers (labelled C18C18, C18C9, and C18C4 based on monomer chain lengths) free of residual solvent and catalyst. Three diester dialkyne monomers were synthesized with ester chain lengths of 4, 9, and 18 carbons from renewable sources. Significant differences in thermal and mechanical properties were observed between C18C9
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Normayanti, N., Adioro Soetojo, and Nirawati Pribadi. "The difference between residual monomer dentin bonding HEMA and UDMA with acetone and ethanol solvent after binding to type I collagen." Dental Journal (Majalah Kedokteran Gigi) 51, no. 4 (2018): 169. http://dx.doi.org/10.20473/j.djmkg.v51.i4.p169-172.

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Background: In caries and non-caries lesions involving dentine, it is necessary to provide dentine-bonding material to help improve retention between the composite resin and the tooth surface. Composite resin attachment to dentine is influenced by bonding polymerization reactions. In several studies, researchers found that polymerized monomers will experience volume shrinkage because not all will fully polymerize but, rather, become residual monomers that can cause post-operative pain. Purpose: This study aimed to identify the difference in the amount of residual monomers between HEMA- and UDM
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Ilic-Stojanovic, Snezana, Ljubisa Nikolic, Vesna Nikolic, et al. "Influence of monomer and crosslinker molar ratio on the swelling behaviour of thermosensitive hydrogels." Chemical Industry and Chemical Engineering Quarterly 18, no. 1 (2012): 1–9. http://dx.doi.org/10.2298/ciceq110711040i.

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The synthesis of the poly(N-isopropylacrylamide-co-2-hydroxypropylmethacrylate) hydrogel along with the analysis of the residual monomers content and influence of monomer and crosslinker molar ratios on the swelling behaviour was investigated. Synthesis of thermosensitive hydrogel based on N-isopropylacrylamide was carried out with the molar ratios of 5, 10, 15 and 20 mol. % of monomer 2- hydroxypropyl-methacrylate, in the presence of ethylene glycol dimethacrylate as a crosslinker (1, 1.5, 2 and 3 mol. %) and 2,2'-azobis(2-methylpropionitril) as an initiator in acetone. The quantities of resi
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Dissertations / Theses on the topic "Residual monomers"

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Björnsdotter, Maria. "Leaching of Residual Monomers, Oligomers and Additives from Polyethylene, Polypropylene, Polyvinyl Chloride, High-density Polyethylene and Polystyrene Virgin Plastics." Thesis, Örebro universitet, Institutionen för naturvetenskap och teknik, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-45888.

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Plastic debris are accumulating in our oceans and are degraded into smaller pieces which eventually becomes small enough to be available to lower thropic level organisms. Microplastics, commonly defined as plastic particles <5 mm, are globally distributed and found at remote locations far away from industrialized and populated areas. The effects of macro sized plastics is well understood whilst the effects of microplastics is hard to predict. It is known that microplastics act as transfer vectors for a wide range of toxic chemicals into organisms, and it is also known that the particle itse
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Amaral, Aline Bassi Denis Bordini do. "Avaliação do grau de conversão monomérica, parâmetros de cinética de polimerização e determinação de monômeros residuais em resinas experimentais." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/75/75135/tde-25072012-090212/.

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Este estudo teve como objetivo investigar múltiplos aspectos relacionados a polimerização da resina composta como: o grau de conversão monomérica (GC), parâmetros da cinética de polimerização e a determinação de monômeros residuais TEGDMA e BisGMA, além de avaliar o desempenho de aparelhos fotoativadores. As resinas compostas experimentais foram manipuladas variando-se os fotoiniciadores R1-) canforoquinona/amina, R2-) PPD/amina, R3-) PPD + canforoquinona/amina) e foram utilizados dois aparelhos para a fotoativação (I-) lâmpada halógena (Demetron LC/ SDS Kerr-USA) e II-) LED (Poly 6
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龍英奇 and Ying-kei Christie Lung. "Residual monomer in denture base acrylic." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2003. http://hub.hku.hk/bib/B42577743.

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Lung, Ying-kei Christie. "Residual monomer in denture base acrylic." Click to view the E-thesis via HKUTO, 2003. http://sunzi.lib.hku.hk/hkuto/record/B42577743.

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Ugarte, Guerra Francisco. "Sistema de monomios para un cuerpo residual algebraicamente cerrado." Pontificia Universidad Católica del Perú, 2012. http://repositorio.pucp.edu.pe/index/handle/123456789/97376.

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Ugarte, Guerra Francisco. "Sistema de monomios para un cuerpo residual real cerrado." Pontificia Universidad Católica del Perú, 2012. http://repositorio.pucp.edu.pe/index/handle/123456789/95452.

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Para extender tecnicas tipo Polígono de Newton aecuaciones algebraicas con coeficientes en cuerpos valorados,es necesario un desarrollo en serie de los coeficientes y paraello se requiere fijar los monomios, lo cual no siempre esposible. En este artículo probaremos que si el cuerpovalorado es henseliano y el cuerpo residual asociado a lavaloración es real cerrado, la construcción del sistema demonomios es posible.
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Mascioli, Cássio Marcelo. "Um processo para redução de monômero residual na produção de poli(pirrolidona vinílica) e análise da agregação de valor ao polímero." Florianópolis, SC, 2007. http://repositorio.ufsc.br/xmlui/handle/123456789/89605.

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Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia de Produção.<br>Made available in DSpace on 2012-10-23T00:09:31Z (GMT). No. of bitstreams: 1 247319.pdf: 1416708 bytes, checksum: 19b894ecea0cfdd7d12ca60b2a58e9b1 (MD5)<br>Neste trabalho é desenvolvida uma metodologia destinada à redução das concentrações de monômero residual em poli(pirrolidona vinílica) visando à obtenção de polímero com elevado valor agregado. As técnicas utilizadas foram radiação UV-C de baixa intensidade e stripping com vapor. Experimentos utilizando-se r
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Urban, Vanessa Migliorini [UNESP]. "Efeito de diferentes tratamentos térmicos sobre o conteúdo de monômero residual de resinas acrílicas para reembasamento." Universidade Estadual Paulista (UNESP), 2003. http://hdl.handle.net/11449/97307.

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Made available in DSpace on 2014-06-11T19:28:56Z (GMT). No. of bitstreams: 0 Previous issue date: 2003-02-27Bitstream added on 2014-06-13T19:16:53Z : No. of bitstreams: 1 urban_vm_me_arafo.pdf: 1219036 bytes, checksum: 4e3be4eb79ce75a36f6d11fd248eff4f (MD5)<br>Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)<br>O objetivo deste estudo foi estabelecer, inicialmente, um método analítico em CLAE, para comparar o conteúdo de monômero residual de uma resina autopolimerizável para reembasamento imediato (Duraliner II - D) e uma resina termopolimerizável utilizada na confecção de bases
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Junior, Tarcisio José de Arruda Paes. ""Estudo das resinas acrílicas para bases de próteses totais com relação à resistência flexural, e à quantidade de monômero residual superficial"." Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/23/23137/tde-14102005-122104/.

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O objetivo deste trabalho foi o de avaliar a resistência à flexão e a quantidade de monômero residual superficial em resinas acrílicas para bases de próteses totais. Para tanto foram confeccionados corpos-de-prova nas dimensões de 2.5mm x 10mm x 65mm, utilizados em ambas as análises. Padronizou-se o processo de inclusão no qual foram empregadas muflas plásticas reforçadas por fibras de vidro. Sete grupos foram constituídos, de acordo com o tipo de processamento empregado na polimerização das resinas: Ac (Acron-MC) e Vw (Vipi-Wave) de ativação por energia de microondas; Lt (Lucitone 550 – grupo
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Urban, Vanessa Migliorini. "Efeito de diferentes tratamentos térmicos sobre o conteúdo de monômero residual de resinas acrílicas para reembasamento /." Araraquara : [s.n.], 2003. http://hdl.handle.net/11449/97307.

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Resumo: O objetivo deste estudo foi estabelecer, inicialmente, um método analítico em CLAE, para comparar o conteúdo de monômero residual de uma resina autopolimerizável para reembasamento imediato (Duraliner II - D) e uma resina termopolimerizável utilizada na confecção de bases de próteses (Lucitone 550 - L). Além disso, foi avaliado o efeito de dois tratamentos térmicos sobre esse conteúdo. Os monômeros utilizados como padrões foram o MMA (resina L) e o BMA (resina D). As condições cromatográficas para a análise foram: coluna ODS (15,0 x 0,46 cm), com 5 mm de tamanho de partícular e 100 Å d
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Book chapters on the topic "Residual monomers"

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Gooch, Jan W. "Residual Monomer." In Encyclopedic Dictionary of Polymers. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_9928.

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Kemmere, Maartje F., Marcus A. van Schilt, Marc A. Jacobs, and Jos T. F. Keurentjes. "Reduction of Residual Monomer in Latex Products Using High-Pressure Carbon Dioxide." In Supercritical Carbon Dioxide. Wiley-VCH Verlag GmbH & Co. KGaA, 2006. http://dx.doi.org/10.1002/3527606726.ch14.

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Wan, Zi Yi, Ting Fei Xi, P. Zhao, Y. Sun, and Z. G. Feng. "Determination of Residual Acrylamide Monomer in Medical Polyacrylamide Hydrogel by HPLC-SPE." In Advanced Biomaterials VI. Trans Tech Publications Ltd., 2005. http://dx.doi.org/10.4028/0-87849-967-9.405.

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Kemmer, Diana, and Petra Schmid. "Migration of Residual Monomers From Plastics Into Food." In Reference Module in Food Science. Elsevier, 2017. http://dx.doi.org/10.1016/b978-0-08-100596-5.21430-3.

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"Residual monomer." In Encyclopedic Dictionary of Polymers. Springer New York, 2007. http://dx.doi.org/10.1007/978-0-387-30160-0_9746.

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Ray, Sujay, and Arundhati Banerjee. "In Silico Perspective into Interactions and Mutations in Human TLR4 and Ebola Glycoprotein." In Advances in Medical Technologies and Clinical Practice. IGI Global, 2016. http://dx.doi.org/10.4018/978-1-5225-0362-0.ch008.

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Toll-Like Receptor-4 (TLR4) senses life-threatening Ebola virus Glycoprotein (GP) and produces pro-inflammatory cytokines, resulting in lethal Ebola virus infections. GP2-subunit of Ebola promotes viral entry via membrane fusion. The present study models, optimizes and demonstrates the 3D monomer of the responsible human protein. The essential residue (studied from wet-laboratory research) was observed to be functionally conserved from multiple-sequence alignment. Thus, after performing point-mutation, the mutant protein was satisfactorily re-modelled; keeping its functionality preserved. Comparable residual participation in GP2 and each of the proteins was examined, individually. Stability of the proteins and protein-GP2 complexes on mutation; were discerned via energy calculations, solvent-accessibility area and conformational switching, with supportive statistical significances. Therefore, this probe paves a pathway to examine the weaker interaction of the stable mutated human protein with Ebola GP2 protein, thereby defending the Ebola viral entry.
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Banerjee, Arundhati, and Sujay Ray. "An Optimized In Silico Neuroinformatics Approach." In Handbook of Research on Natural Computing for Optimization Problems. IGI Global, 2016. http://dx.doi.org/10.4018/978-1-5225-0058-2.ch032.

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A computationally optimized molecular analysis into the cell-fate regulations from embryonic development is one of the unexplored zones in human neurogenic field. It is governed by SOX11 (Sex determining regions-Y bOX-11) protein domain's interaction with DNA. In the present study, 3D monomer of the responsible domain of SOX11 was constructed, simulated and analyzed. Residues indulged with DNA interaction were examined. The observed conserved residue, Arg3 and Arg16 in the wild-type SOX11-DNA interaction were mutated with Ala3 and Ala16. Mutated SOX11-HMG protein sequence was re-modeled and optimized. Residue-level alteration on DNA interaction was examined. On mutation, stability of the proteins (on DNA interaction) and protein-DNA complexes were discerned via energy-calculating parameters, solvent-accessibility area, electrostatic surface-potential and conformational switching, with supportive statistical significance. Therefore, this probe provides an outlook to discern SOX11 to interact firmly with DNA via mutations and thereby perform cell-fate determinations more efficiently.
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Han, Chang Dae. "Plasticating Single-Screw Extrusion." In Rheology and Processing of Polymeric Materials: Volume 2: Polymer Processing. Oxford University Press, 2006. http://dx.doi.org/10.1093/oso/9780195187830.003.0007.

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There are two types of extruder: (1) single-screw extruders and (2) twin-screw extruders. The single-screw extruder is one of the most important pieces of equipment in the processing of thermoplastic polymers. Accordingly, during the past three decades, many attempts have been made to analyze the performance of single-screw extruders using different degrees of mathematical sophistication (Cox and Fenner 1980; Donovan 1971; Edmondson and Fenner 1975; Elbirli et al. 1983, 1984; Halmos et al. 1978; Han et al. 1991a, 1991b, 1996; Lee and Han 1990; Lindt 1976; Lindt and Elbirli 1985; Shapiro et al. 1976; Tadmor 1966; Tadmor and Klein 1970; Tadmor et al. 1967). There are two types of single-screw extruders: (a) plasticating and (b) melt-conveying. The plasticating single-screw extruder conveys a solid polymer from the feed section to the melting section, where most of the melting (or softening) occurs, and then transports the melted or softened polymer to a shaping device (e.g., dies and molds). The meltconveying extruder does not include a melting section; it simply transports an already softened polymer to a shaping device (e.g., rubber extruder). Single-screw extruders are used for various purposes, such as melting and pumping, compounding with an additive(s) or filler, cooling and mixing, removing residual monomers or solvents in polymer (i.e., polymer devolatilization), and cross-linking reactions. Single-screw extruders are simple to operate and relatively inexpensive as compared with twin-screw extruders. However, there are situations where a single-screw extruder cannot function as effectively as a twin-screw extruder. In the design of plasticating single-screw extruders, one needs information on (1) the physical and thermal properties of polymers (e.g., friction coefficient between the solid polymer and barrel wall, thermal conductivity of polymer, specific heat as a function of temperature, melting point of polymer, and heat of fusion of polymer) and (2) rheological properties of polymers as functions of shear rate and temperature. Due to the complexity involved in the design of extruders, it is highly desirable for one to establish relationships between material variables and processing variables.
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Bae, Seongwoong, Shinhyuk Kim, and Jay H. Lee. "CFD-assisted Modeling and Analysis on Residual Monomer Stripping Using Spinning Cone Column." In 13th International Symposium on Process Systems Engineering (PSE 2018). Elsevier, 2018. http://dx.doi.org/10.1016/b978-0-444-64241-7.50231-7.

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Watson, J. E., and R. F. Harris. "Diffusion-Linked Microbial Metabolism in the Vadose Zone." In Vadose Zone Hydrology. Oxford University Press, 1999. http://dx.doi.org/10.1093/oso/9780195109900.003.0011.

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Figure 7.1 is a schematic of nutrient and contaminant transformations and cycling in the vadose zone. As detailed in Harris and Arnold (1995), higher plants take up C, N, P, and S in their most oxidized forms and use, via photosynthesis, the Sun’s energy and low-energy electrons from the oxygen in water to convert the oxidized forms of these essential elements into the relatively high energy reduced forms comprising plant biomass. Following plant death, the biomass residues enter the soil and are attacked by soil organisms as a source of food. The plant residues are depolymerized and the reduced, high-energy monomers are assimilated in part into soil organism biomass, and in part are used as electron donors to combine with the most thermodynamically efficient electron acceptors for dissimilatory energy generation to drive growth and maintenance reactions. In aerobic zones, oxygen is the preferred electron acceptor as long as it is nonlimiting. Death of soil organisms produces dead biomass which re-enters the biological reactor. Ultimately, via respiration in aerobic soils, all the reduced C, N, P, and S materials are released as their oxidized forms, and oxygen is reduced to water to complete the cycle. Ideally, the cycle is conservative, particularly from the standpoint of nonleakage of nutrients, such as nitrate, into the groundwater. Similarly, contaminants entering the vadose zone, either as a function of agronomic use or by accident, should ideally be integrated into the natural nutrient cycles and converted to harmless by-products for assimilation and dissimilation by soil organisms and higher plants (Liu, 1994). Management of nutrient and contaminant transformations by the soil organisms requires a thorough understanding of the ecophysiological and solute transport ground rules that control the nature and rates of transformation options available to the soil organisms. In models of chemical transport and transformation through the vadose zone, colonies of microorganisms are frequently treated as a homogeneous biofilm reactor (Grant and Rochette, 1994). Often, modeling efforts are focused on environmental conditions external to the microbial colony. This consideration of the colony as a biofilm with relatively constant nutrient uptake rates ignores the growth differentiation that occurs as the colony develops
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Conference papers on the topic "Residual monomers"

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Boboia, S., M. Moldovan, and I. Ardelean. "Determination of residual monomers resulting from the chemical polymerization process of dental materials." In PROCESSES IN ISOTOPES AND MOLECULES (PIM 2013). AIP, 2013. http://dx.doi.org/10.1063/1.4833703.

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Deriu, Marco A., Søren Enemark, Emiliano Votta, Franco M. Montevecchi, Alberto Redaelli, and Monica Soncini. "Bottom-Up Mesoscale Model of Microtubule." In ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-176115.

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Microtubules (MTs) are fundamental structural elements in the cytoskeleton of all eukaryotic cells. The MTs are hollow cylinder-shaped biopolymers with inner and outer diameter of about 18 and 30 nm respectively and length ranging from 1 to 10 μm. They are constituted by αβ-tubulins arranged in protofilaments with head-to-tail motif. The protofilaments bind together laterally along the MT’s long axis with a slight shift generating a spiral with a pitch of 2, 3 or 4 monomers’ length [1]. The building-block of the MT, αβ-tubulin, is a hetero-dimer made of two globular monomers, α- and β-tubulin.
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Francis, C. W., and V. J. Marder. "RAPID FORMATION OF LARGE MOLECULAR WEIGHT O-P0LYMERS IN CROSSLINKED FIBRIN INDUCED BY HIGH FACTOR XIII CONCENTRATIONS: ROLE OF PLATELET FACTOR XIII." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643311.

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Following fibrin polymerization, activated factor XIII stabilizes the clot by catalyzing the formation of specific intermolecular covalent crosslinks between pairs of y chains to form dimers and also among two or more a chains to form polymers. We have identified a series of previously uncharacterized a chain polymers with a wide range of sizes, including some with apparent Mr in excess of several million. Additionally, we establish the role of high concentrations of factor XIII in the extent and rate of α-polymer formation and provide evidence that the factor XIII required can be provided by
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4

Minno, G. Di, A. M. Cerbone, F. Cirillo, et al. "ABNORMAL FIBRINOGEN (FIBRINOGEN NAPLES) CHARACTERIZED BY DETECTIVE INTERACTION WITH THROMBIN AND PLASMIN IN TWO YOUNG SIBLINGS WITH ARTERIAL THROMBOSIS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644698.

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Prolonged thrombin time (partially corrected by calcium chloride) and normal reptilase time were found in the plasma of two siblings with arterial thrombosis. Their purified fibrinogen showed similar abnormalities as well as impaired fibrino-peptide release in response to thrombin, delayed polymerization of pre-formed fibrin monomers and normal sialic content. Binding of radiolabelled thrombin by patient's fibrin was 30% of normal. Supernatants from patients' fibrin clots contained abnormal amounts of thrombin (not adsorbed by fibrin) and caused abnormal enhancement of platelet aggregation and
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5

Deriu, Marco A., Monica Soncini, Mario Orsi, et al. "Elastic Network Normal Mode Analysis for Microtubule Mechanics." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-206618.

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The cellular microtubules MTs are hollow cylinder-shaped biopolymers with inner and outer diameter of about 17 and 25 nm and length ranging from 1 to 10 μm. They are constituted by αβ-tubulins arranged in protofilaments with a head-to-tail motif [1]. The protofilaments bind together laterally along the MT’s long axis with a slight shift generating a spiral with a pitch of 2, 3 or 4 monomers’ length (Fig.1a). The building-block of the MT, the αβ-tubulin, is a hetero-dimer made of two globular monomers, α- and β-tubulin, each of them consisting of about 450 residues with high degree of sequence
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Bidone, Tamara C., Marco A. Deriu, Giacomo Di Benedetto, Diana Massai, and Umberto Morbiducci. "Insights Into the Molecular Mechanisms of Actin Dynamics: A Multiscale Modeling Approach." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53417.

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Actin dynamics, which is at the basis of many fundamental cellular processes as cell migration [1], is governed by the self-assembly and disassembly of actin monomers (G-actin) that, in turn, are determined by the kinetics of ATP hydrolysis and by the local concentrations of Mg2+ and Ca2+ [2]. During cell migration, interactions of the actin filaments (F-actin) with different nucleotide-cation complexes induce local topological rearrangements, because the filament building G-actins undergo conformational shifts between multiple equilibrium states separated by low-energy barriers. For example,
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7

Koh, Sung K., and G. K. Ananthasuresh. "Design of HP Models of Proteins by Energy Gap Criterion Using Continuous Modeling and Optimization." In ASME 2004 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2004. http://dx.doi.org/10.1115/detc2004-57598.

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The sequence of 20 types of amino acid residues in a heteropolymer chain of a protein is believed to be the basis for the 3-D conformation (folded structure) that a protein assumes to serve its functions. We present a deterministic optimization method to design the sequence of a simplified model of proteins for a desired conformation. A design methodology developed for the topology optimization of compliant mechanisms is adapted here by converting the discrete combinatorial problem of protein sequence design to a continuous optimization problem. It builds upon our recent work which used a mini
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8

Mantaj, Julia, Paul J. M. Jackson, Khondaker Miraz Jackson, and David E. Thurston. "Abstract 4778: Covalent bonding of a C8-conjugated pyrrolobenzodiazepine (PBD) monomer and dimer to a terminal guanine residue of DNA duplex and hairpin fragments." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-4778.

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9

Meade, J. B., C. M. Noyes, and F. C. Church. "IDENTIFICATION OF LYSINES IN HUMAN THROMBIN ESSENTIAL FOR HEPARIN BINDING AND CLOTTING ACTIVITY." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644662.

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We are studying human thrombin (IIa) in order to determine the significance of particular amino acid residues critical for interaction with various substrates and cofactors.Previously, we demonstrated the importance of lysyl residues of Ila during interaction with heparin as well as fibrinogen (Griffith, M.J., (1979) J. Biol. Chem. 254:3401; Church, F.C., et al., (1985) J. Biol. Chem. 260:4936). Identification of these essential lysyl residues in Ila has been approached by chemical modification using the amino group-specific reagent pyridoxal-5'-phosphate (PLP) in the presence and absence of h
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10

Terukina, S., M. Matsuda, N. Yoshida, K. Yamazumi, Y. Takeda та T. Takano. "TWO ABNORMAL FIBRINOGENS DESIGNATED AS OSAKA II AND MORIOKA WITH A HITHERTO UNIDENTIFIED AMINO ACID SUBSTITUTION; γARG-275 BY CYS". У XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644701.

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A hitherto unidentified amino acid substitution of γ Arg-275 by Cys has been found in two abnormal fibrinogens, Osaka II and Morioka. The propositi are both asymptomatic heterozygotes for the abnormality characterized by altered polymerization of fibrin monomers. Reducing SDS-PAGE revealed that fibrinogens derived from thé propositi both consist of two populations; one with a normal and the other with an abnormal longer γ-chain by 0.5 Kd.The γ-γ cross-linking took place nearly normally, however. Analyzing plasmic digests of fibrinogen by SDS-PAGE, we located the abnormality residing in the γ-c
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