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1

Börjesson, Stefan. "Antibiotic Resistance in Wastewater : Methicillin-resistant Staphylococcus aureus (MRSA)and antibiotic resistance genes." Doctoral thesis, Linköpings universitet, Medicinsk mikrobiologi, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-17709.

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A large part of the antibiotics consumed ends up in wastewater, and in the wastewater the antibiotics may exert selective pressure for or maintain resistance among microorganisms. Antibiotic resistant bacteria and genes encoding antibiotic resistance are commonly detected in wastewater, often at higher rates and concentrations compared to surface water. Wastewater can also provide favourable conditions for the growth of a diverse bacterial community, which constitutes a basis for the selection and spread of antibiotic resistance. Therefore, wastewater treatment plants have been suggested to pl
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2

Rusin, Patricia Anne. "Antibiotic resistance, heavy metal resistance, chlorine resistance and phage typing patterns of fecal coliforms isolated from secondary effluent." Diss., The University of Arizona, 1989. http://hdl.handle.net/10150/184925.

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Antibiotic resistance profiles of fecal coliform isolated from unchlorinated and chlorinated secondary effluent were determined. Of 332 fecal coliforms isolated from chlorinated effluent a mean of 48% were multiply antibiotic resistant. In contrast, of 347 fecal coliforms isolated from unchlorinated effluent a mean of 29% were multiply antibiotic resistant. Resistance to ampicillin, cephalothin, and carbenicillin were significantly higher in the former than the latter. Randomly selected isolates survived and/or grew in sterile and unsterile effluent retaining resistance patterns for 40 days. R
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3

Bamarouf, Abdulaziz Omar. "Molecular typing and analysis of antimicrobial resistance in clinical isolates of Streptococcus pneumoniae and Haemophilus influenzae." Thesis, University of Edinburgh, 2000. http://hdl.handle.net/1842/22499.

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b-Lactams are widely used to treat <i>S. pneumoniae </i>and <i>H. influenzae</i> respiratory infections. However, resistance to b-lactams is increasing in the UK. To establish if this results from spread of a small number of resistant strains or from a wider emergence of resistance, the molecular type and mechanisms of resistance in <i>S. pneumoniae</i> and <i>H. influenzae </i>isolates, from throughout the UK, were determined. Resistance of <i>S. pneumoniae </i>to penicillin is due entirely to the development of altered forms of the high molecular weight penicillin binding proteins (PBPs) and
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4

Amiali, Mohamed Nassim. "Identification of antibiotic-resistant staphylococci and epidemiological typing of methicillin-resistant Staphylococcus aureus by Fourier transform infrared spectroscopy." Thesis, McGill University, 2003. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=19525.

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Staphylococci strains are among the most widespread multidrug-resistant nosocomial pathogens in Canada. Rapid and accurate identification and epidemiological typing of methicillin-resistant S. aureus (MRSA) and its discrimination from coagulase-negative staphylococci (CNS) and glycopeptide-intermediate S. aureus (GISA) are crucial for appropriate therapy and for monitoring and limiting intra- and inter-hospital spread of epidemic MRSA strains. Although pulsed-field gel electrophoresis and polymerase chain reaction methods for the identification of MRSA are reliable, they are technically demand
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5

Rato, Márcia Alexandra Gonçalves. "Epidemiological characterization, antimicrobial resistance and virulence mechanisms of human and animal streptococci." Doctoral thesis, Faculdade de Ciências e Tecnologia, 2011. http://hdl.handle.net/10362/7501.

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Dissertação para obtenção do Grau de Doutor em Biologia<br>Streptococcus agalactiae (Group B Streptococcus - GBS), Streptococcus dysgalactiae subsp. dysgalactiae (Group C Streptococcus - GCS) and Streptococcus uberis are relevant mastitis pathogens, a highly prevalent and costly disease in the dairy industry due to antibiotherapy and loss in milk production. However, molecular characterization of field isolates of Streptococcus spp. occurring in Portugal was not known prior to our studies and is important to improve therapeutic and disease control programs. The aims of this study were the ide
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6

Shang, Judith Dzelambong. "Genotypic and phenotypic typing of oral and vaginal isolates of C. albicans from HIV positive and negative subjects from Cameroon, Tanzania and the U.K." Thesis, King's College London (University of London), 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.309447.

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7

Tiao, Narry. "Phenotypic And Genotypic Characterization Of Staphylococci From Dairy In Northeast Brazil." The Ohio State University, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=osu1222093339.

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8

Patel, Nehal J. "Comparsion [sic] of antibiotic sensitivity profiles, molecular typing patterns, and attribution of Salmonella enterica serotype Newport in the U.S., 2003-2006." unrestricted, 2007. http://etd.gsu.edu/theses/available/etd-07262007-154647/.

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Thesis (M.P.H.)--Georgia State University, 2007.<br>Title from file title page. Karen Gieseker, committee chair; Michael Eriksen, Peter Gerner-Smidt, Kelley Hise, committee members. Electronic text (105 p. : ill. (some col.)) : digital, PDF file. Description based on contents viewed Nov. 28, 2007. Includes bibliographical references (p.101-105).
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9

Souza, Camila Sena Martins de [UNESP]. "Staphylococcus aureus: resistência de virulência e tipagem de MRSA pelas técnicas de MLST e spa typing." Universidade Estadual Paulista (UNESP), 2014. http://hdl.handle.net/11449/108784.

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Made available in DSpace on 2014-08-13T14:50:57Z (GMT). No. of bitstreams: 0 Previous issue date: 2014-02-19Bitstream added on 2014-08-13T17:59:55Z : No. of bitstreams: 1 000768735.pdf: 1378869 bytes, checksum: 208d6f9ea0a8b866c4aaf52ade9bcdc9 (MD5)<br>Staphylococcus aureus se destaca por sua patogenicidade e alta frequência, permitindo que este agente seja capaz de produzir doenças tanto em indivíduos sadios quanto em imunocomprometidos por sua fácil disseminação. O objetivo deste trabalho foi caracterizar a distribuição de clones de S. aureus sensíveis e resistentes à meticilina (MSSA/MRSA
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10

Maseko, Phiri Thabiso. "Predictive value of gene mutations as a diagnostic tool for ART resistance in a Zambian population." Thesis, Stellenbosch : Stellenbosch University, 2012. http://hdl.handle.net/10019.1/71845.

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Thesis (MSc)--Stellenbosch University, 2012.<br>Background: While Selection of reverse transcriptase (RT) mutation has been reported frequently, protease (PR) mutations on antiretroviral therapy (ART) including boosted Protease inhibitor (PI) have not been reported as much in Zambia. Affordable in-house genotyping assays can been used to expand the number of patients receiving drug resistance geno-typing, which can aid in determining prevalence of RT/PI emerging mutations. Methods: A previously published drug resistance genotyping assay was modified and used to genotype RT and PR genes.
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11

Magri, Marcello Mihailenko Chaves. "Caracterização molecular e perfil de sensibilidade de Candida tropicalis isoladas em corrente sanguínea e cateter de pacientes internados em hospitais de ensino." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/5/5134/tde-07022013-115954/.

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Infecções causadas por Candida tropicalis (C. tropicalis) são associados à elevada morbi-mortalidade, e foram consideradas como importantes causas de infecção de corrente sanguínea no Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HCFMUSP) de março de 1998 a março de 2001. Adicionalmente, são responsáveis pelo aumento do tempo e dos custos de hospitalização e necessidade de cuidados intensivos. Esse estudo tem como objetivo a caracterização molecular e perfil de sensibilidade de 61 isolados de C. tropicalis a partir de candidemias no HCFMUSP e Universidade Estadua
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12

Pinto, Taiz Siqueira. "Caracterização fenotípica de Cepas de Staphylococcus aureus isoladas de queijos ricota." Universidade Federal da Paraí­ba, 2011. http://tede.biblioteca.ufpb.br:8080/handle/tede/4316.

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Made available in DSpace on 2015-04-17T15:03:08Z (GMT). No. of bitstreams: 1 arquivototal.pdf: 760407 bytes, checksum: 36ff52186c6a7e31beb2bd5ddc4a7fa0 (MD5) Previous issue date: 2011-03-25<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES<br>This study aimed to isolate strains of Staphylococcus aureus in ricotta cheeses and to characterize them respecting phenotypic markers of lipolytic activity, and bacteriocin typing and resistance typing. For isolation, were acquired 11 samples of different brands of ricotta cheese sold in supermarkets in João Pessoa - Paraíba. Among
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13

Santos, Thaynara Gonzaga. "Patotipagem, tipagem filogenética, determinação de resistência aos antimicrobianos em Escherichia coli uropatogênica." Universidade Federal de Goiás, 2018. http://repositorio.bc.ufg.br/tede/handle/tede/8243.

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Submitted by Liliane Ferreira (ljuvencia30@gmail.com) on 2018-03-21T12:04:52Z No. of bitstreams: 2 Dissertação - Thaynara Gonzaga Santos - 2018.pdf: 3745794 bytes, checksum: db8d5a41bb72d586b2468abd5e6ad7b6 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)<br>Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2018-03-22T10:33:07Z (GMT) No. of bitstreams: 2 Dissertação - Thaynara Gonzaga Santos - 2018.pdf: 3745794 bytes, checksum: db8d5a41bb72d586b2468abd5e6ad7b6 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)<br>M
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Anna, Olsson. "Evaluation of the molecular epidemiology of ESBL-producing Escherichia coli associated with blood stream infections in China." Thesis, Uppsala universitet, Institutionen för medicinsk biokemi och mikrobiologi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-334657.

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The increasing number of Extended Spectrum Beta-Lactamase (ESBL) producing Escherichia coli (E. coli) associated with sepsis in China is the reason for designing the current study. During 2014-2016, thirty hospitals representing 10 different provinces in China was involved in collecting E. coli isolates causing blood stream infections. Early treatment with suitable antibiotics have been found to be of lifesaving importance in the case of care for septic patients. Thorough understanding of the pathogens involved is therefore crucial. Using antimicrobial susceptibility testing, PCR and Multi Loc
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15

Box, Matthew. "Multiple-locus variable-number tandem-repeat analysis (MLVA) for clonal characterization of methicillin resistant Staphylococcus aureus strains." Thesis, Birmingham, Ala. : University of Alabama at Birmingham, 2006. https://www.mhsl.uab.edu/dt/2008r/box.pdf.

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16

Fleming, Maria Emília de Castro Kling. "Análise da resistência a antimicrobianos em microrganismos isolados de hemoculturas em hospitais de Niterói." Niterói, 2017. https://app.uff.br/riuff/handle/1/3356.

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Submitted by Biblioteca da Faculdade de Farmácia (bff@ndc.uff.br) on 2017-04-18T16:42:00Z No. of bitstreams: 1 Fleming, Maria Emília de Castro Kling [Dissertação, 2011].pdf: 3850457 bytes, checksum: 76e7a64373d2898f956190ecd2aa26c3 (MD5)<br>Made available in DSpace on 2017-04-18T16:42:00Z (GMT). No. of bitstreams: 1 Fleming, Maria Emília de Castro Kling [Dissertação, 2011].pdf: 3850457 bytes, checksum: 76e7a64373d2898f956190ecd2aa26c3 (MD5)<br>Introdução: As infecções de corrente sanguínea estão entre as mais graves infecções, principalmente se causadas por microrganismos resistentes a a
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17

Rowlands, Ruth Estela Gravato. "Caracterização fenotípica e genotípica de Listeria monocytogenes isoladas de produtos cárneos crus comercializados no município de São Paulo." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/9/9131/tde-29042014-163248/.

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Listeria monocytogenes é um importante patógeno de origem alimentar que causa listeriose, infecção severa que acomete, principalmente, gestantes, idosos, crianças e imunocomprometidos, e que apresenta elevada taxa de mortalidade. A bactéria está amplamente distribuída no ambiente e é comumente encontrada em produtos cárneos. O presente estudo teve como objetivos caracterizar 439 isolados de L. monocytogenes obtidos de salsicha bovina e produtos cárneos crus (carne moída, linguiça suína e coxa de frango) refrigerados, adquiridos no comércio do município de São Paulo, e previamente submetidos à
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18

Campioni, Fábio. "Tipagem molecular e análise da diversidade genética de linhagens de Salmonella Enteritidis isoladas de humanos, alimentos e frangos no Brasil." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/60/60135/tde-27112013-095252/.

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A doença decorrente da infecção por Salmonella é um dos maiores problemas de saúde no mundo em termos de morbidade e mortalidade. Entre as sorovariedades de Salmonella, a sorovariedade Enteritidis é a de maior ocorrência mundial e compreende linhagens que tem seu nicho biológico relacionado a frangos e ovos. Várias metodologias de tipagem fenotípicas e genotípicas foram desenvolvidas a fim de se delinear a epidemiologia das infecções por S. Enteritidis. Entretanto a tipagem fenotípica usualmente falha em discriminar linhagens relacionadas das nãorelacionadas epidemiologicamente e apresenta pro
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19

Charretier, Yannick. "Identification, résistance, virulence et typage : une nouvelle application de la spectrométrie de masse pour la microbiologie clinique." Thesis, Lyon 1, 2013. http://www.theses.fr/2013LYO10040.

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La spectrométrie de masse de type MALDI-TOF vient d'être largement adoptée dans les laboratoires de microbiologie clinique, qu'ils soient de ville ou hospitalier. Le MALDI-TOF est maintenant utilisée en routine pour l'identification des micro-organismes. Les micro-organismes sont identifiés en quelques minutes à un coût minime et avec une meilleure précision qu'en utilisant les méthodes conventionnelles. Le MALDI-TOF permet une identification microbienne révolutionnaire mais il ne permet pas aisément la détection de résistances aux antimicrobiens ou de facteurs de virulence. Le travail de thès
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20

Andrigheto, Cristiano. "Disseminação de Salmonella Enteritidis isoladas em uma cadeia produtiva industrial avícola: determinação do perfil de resistência a antimicrobianos e caracterização genotípica." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/9/9131/tde-25072017-152730/.

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Salmonella é um dos principais agentes de enfermidades transmitidas por alimentos em diversos países, sendo a carne de frango um dos principais veículos envolvidos em surtos. O Brasil vem se destacando como um dos maiores exportadores mundiais deste alimento. O ambiente de criação das aves é apontado como um importante foco de infecção das aves e o ambiente industrial de abate e processamento é importante na disseminação deste ·microrganismo. Na busca pela produção de alimentos seguros do ponto de vista microbiológico, uma das ferramentas utilizadas é a subtipagem de microrganismos isolados ao
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21

Denis, Olivier. "Contribution to the molecular epidemiology of methicillin-resistant staphylococcus aureus (MRSA) in Belgian populations." Doctoral thesis, Universite Libre de Bruxelles, 2009. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/210195.

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Staphylococcus aureus est une bactérie commensale et pathogène qui s’est rapidement adaptée à la pression sélective des antibiotiques entraînant la diffusion de souches résistantes à la méticilline (MRSA). En Belgique, des souches appelées Healthcareassociated (HA)-MRSA sont devenues endémiques dans les hôpitaux, causant de nombreuses épidémies durant les années 90.<p>Parallèlement, des cas d’infections communautaires par des souches appelées Community-associated (CA)-MRSA produisant la leucocidine de Panton-Valentine (PVL) ont été rapportées en Europe, en Australie et aux USA, chez des patien
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22

Heijden, Inneke Marie van der. "Caracterização molecular de isolados de Staphylococcus aureus resistentes à meticilina (MRSA) obtidos de colonização e infecção de pacientes hepatopatas e transplantados hepáticos." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/5/5134/tde-13012015-104124/.

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MRSA é um importante agente de colonização e infecção em pacientes hepatopatas e transplantados de fígado. Este estudo tem como objetivo avaliar a clonalidade e a virulência de isolados MRSA de pacientes hepatopatas atendidos no Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo. De agosto de 2010 a janeiro de 2012, foram coletados swabs nasais e inguinais de 190 pacientes (126 pré-transplante e 64 de pós-transplante). Isolados de MRSA foram identificados fenotipicamente e foi realizada detecção de genes de virulência, caracterização do tipo de SCCmec, análise de polim
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23

Caddick, James M. "Molecular typing of hospital-acquired, community-acquired and multidrug-resistant methicillin-resistant staphylococcus aureus." Thesis, Aston University, 2005. http://publications.aston.ac.uk/11028/.

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24

Rettberg, Jill Walker. "The molecular characterisation and rapid detection of methicillin-resistant Staphylococcus aureus." Thesis, Manchester Metropolitan University, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.311205.

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25

Roberts, Jill Carolyne. "Characterization of Community-acquired Methicillin-resistant Staphylococcus aureus by Pulsed-field Gel Electrophoresis, Multilocus Sequence Typing, and Staphylococcal Protein A Sequencing: Establishing a Strain Typing Database." [Tampa, Fla] : University of South Florida, 2006. http://purl.fcla.edu/usf/dc/et/SFE0001489.

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26

Velasco, Valeria. "Detection and Molecular Typing of Methicillin-Susceptible Staphylococcus Aureus (MSSA) and Methicillin-Resistant Staphylococcus Aureus (MRSA)." Diss., North Dakota State University, 2015. http://hdl.handle.net/10365/24928.

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Methicillin-resistant (MRSA) and multidrug-resistant (MDR) Staphylococcus aureus, and the serotype (ST) 398 have been associated with human and livestock infections, being also detected in retail meat. The aim of this study was to determine the prevalence and molecular types of S. aureus strains from animals, retail raw meat, deli meat, and humans, determining the genetic similarity between the strains. A two-step selective enrichment followed by selective plating were used to isolate S. aureus from animals (n=167), retail raw meat (n=145), and deli meat (n=46). In addition, S. aureus from hea
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27

Luna, Ruth Ann. "The Clinical Utility of Molecular Typing of Multiply-resistant Pseudomonas aeruginosa in Children with Cystic Fibrosis." VCU Scholars Compass, 2010. http://scholarscompass.vcu.edu/etd/2060.

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Chronic infection with P. aeruginosa is expected in patients with cystic fibrosis (CF), but the ability to delay, prevent, or better manage infection with multiply-resistant P. aeruginosa (MRPA) can potentially increase quality of life and extend survival. The Texas Children’s Hospital CF Care Center has identified an endemic MRPA strain (dominant clone), and this study aimed to identify risk factors for acquisition of the clone as well as determine differences in patient outcome associated with subsequent infection with the clone. The study included 71 patients with CF with documented MRPA i
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28

Azevedo, Angela Palamin. "Prevalência e características de Salmonella spp em carne bovina brasileira para exportação: contribuição para uma avaliação de risco." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/9/9131/tde-04052016-172852/.

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O Brasil consolidou-se como o principal produtor e exportador mundial de carne bovina. Estudos microbiológicos, geralmente realizados com amostras de carne coletadas no comércio e não na cadeia produtiva de carne, resultam numa insuficiência de dados a respeito das características fenotípicas e genotípicas das bactérias patogênicas de relevância nos produtos destinados à exportação. Objetivando determinar a prevalência e características de Salmonella spp em carne bovina para exportação, realizou-se a coleta de amostras de superfícies de 200 bovinos adultos, provenientes de 12 fazendas, abatido
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Templer, Stefanie Petra. "Antibiotic resistant enterococci from food and clinical samples : microbiological characterization, molecular typing and genetic relation of strains /." [S.l.] : [s.n.], 2006. http://www.zb.unibe.ch/download/eldiss/06templer_sp.pdf.

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Rodrigues, Marjory Xavier. "Molecular characterization of bacterial isolates and microbiome: study of mastitic milk, bulk tank milk, and cheese processing plants." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/11/11141/tde-30092016-185025/.

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The present study aimed to evaluate bacterial isolates and the microbiome of dairies. The specific aims were: to characterize Staphylococcus spp. isolated from mastitic milk, to evaluate the presence of Lactococcus in mastitic milk as a potential causative agent of mastitis, to evaluate the association between microbiome and milk quality parameters, and to characterize Staphylococcus spp. isolated from production lines of Minas Frescal cheese. The detection of genes encoding virulence factors (enterotoxins (sea, seb, sec, sed, see, seg, seh, sei, selj, selk, sell, selm, seln, selo, selp, seIq,
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Locke, Tiffany. "Methicillin-resistant Staphylococcus Aureus in Canadian Hospitals from 1995 to 2007: A Comparison of Adult and Pediatric Inpatients." Thèse, Université d'Ottawa / University of Ottawa, 2013. http://hdl.handle.net/10393/26110.

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The literature directly comparing the epidemiology of MRSA among adult and pediatric hospitalized patients is strikingly minimal. The objective of this thesis was to identify any differences between these two patient groups. The Canadian Nosocomial Infections Surveillance Program MRSA data (1995 to 2007: n=1,262 pediatric and 35,907 adult cases) were used to compare MRSA clinical and molecular characteristics and rates. Hospital characteristics were modeled using repeated measures Poisson regressions. The molecular and epidemiological characteristics of MRSA differed significantly between adu
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Müller, Stefanie [Verfasser]. "Molecular and functional typing of isolates of the Acinetobacter calcoaceticus-Acinetobacter baumannii complex with emphasis on multi-drug resistant Acinetobacter baumannii / Stefanie Müller." Berlin : Freie Universität Berlin, 2018. http://d-nb.info/115376976X/34.

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Dias, Diana Salvador de Sá. "Molecular characterization of antibiotic resistant clinical isolates." Master's thesis, Universidade de Aveiro, 2017. http://hdl.handle.net/10773/22609.

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Mestrado em Biologia Molecular e Celular<br>A prevalência de isolados bacterianos, da família Enterobacteriaceae, resistentes a cefalosporinas de largo espectro, produtores de β-lactamases de largo espectro (ESBLs) e/ou AmpCs tem vindo a aumentar. Tem sido também reportada a coocorrência de genes que codificam para ESBLs e genes que conferem resistência a outras classes de antibióticos. Esta situação tem como consequências a limitação de opções terapêuticas e o insucesso da terapia, traduzindo-se em taxas de mortalidade e morbilidade mais elevadas. Este trabalho focou-se na caracterizaç
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Petersson, Ramona. "Molecular epidemiology of tuberculosis." Stockholm : Umeå universitet, 2009. http://diss.kib.ki.se/2009/978-91-7409-456-5/.

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Stephens, Alex J. "The development of rapid genotyping methods for methicillin-resistant Staphylococcus aureus." Queensland University of Technology, 2008. http://eprints.qut.edu.au/20172/.

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Methicillin-resistant Staphylococcus aureus (MRSA) is an important human pathogen that is endemic in hospitals all over the world. It has more recently emerged as a serious threat to the general public in the form of community-acquired MRSA. MRSA has been implicated in a wide variety of diseases, ranging from skin infections and food poisoning to more severe and potentially fatal conditions, including; endocarditis, septicaemia and necrotising pneumonia. Treatment of MRSA disease is complicated and can be unsuccessful due to the bacterium's remarkable ability to develop antibiotic resistance.
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Berglund, Carolina. "Molecular epidemiology of methicillin-resistant staphylococcus aureus : epidemiological aspects of MRSA and the dissemination in the community and in hospitals." Doctoral thesis, Örebro universitet, Hälsoakademin, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-2443.

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Methicillin-resistenta Staphylococcus aureus (MRSA) som bär på genen mecA, har förekommit och spridit sig över hela världen, främst i sjukhusmiljö, och orsakat utbrott av vårdrelaterade (så kallade nosokomiala) infektioner. Dessa infektioner kan inte behandlas med stafylokock-penicilliner och MRSA-bakterierna är ofta resistenta även mot flera andra grupper av antibiotika vilket medför att infektionerna ofta är påtagligt svårbehandlade. Under senare år har emellertid allt fler fall beskrivits av samhällsförvärvad MRSA infektion, det vill säga uppträdande av MRSA hos personer som tidigare ej har
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Santos, Sabrina Ferreira. "Caracterização e diversidade molecular do transposon Tn1546, carreador do gene vanA, responsável pela expressão de resistência à vancomicina, em amostras clínicas de diferentes espécies de Enterococcus." Universidade do Estado do Rio de Janeiro, 2014. http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=7598.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>Enterococcus resistentes à vancomicina (VRE) são reconhecidos como importantes patógenos causadores de infecções nosocomiais, configurando um grave problema de saúde pública, principalmente pela escassez de opção terapêutica eficaz. O fenótipo de resistência VanA é o mais frequente, sendo definido pela resistência a altos níveis de vancomicina e teicoplanina. VanA é caracterizado por um conjunto gênico (vanRSHAXYZ) localizado no elemento genético móvel denominado transposon Tn1546. A diversidade de Tn1546 resulta de alterações estr
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"Molecular typing and characterisation of MRSA in Hong Kong." 2004. http://library.cuhk.edu.hk/record=b5892095.

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Hung Ming Wai.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2004.<br>Includes bibliographical references (leaves 146-169).<br>Abstracts in English and Chinese.<br>Abstract --- p.I<br>Abstract (Chinese version) --- p.III<br>Acknowledgments --- p.V<br>Contents --- p.VI<br>List of Tables --- p.XII<br>List of Figures --- p.XIV<br>List of Abbreviations & Symbols --- p.XVII<br>Chapter Chapter 1 --- Introduction --- p.1<br>Chapter 1.1 --- Methicillin-resistant Staphylococcus aureus --- p.1<br>Chapter 1.1.1 --- Definition and Identification --- p.1<br>Chapter 1.1.2 --- Antibiotic re
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Hernandez, Charles Andrew. "Molecular Typing and Antimicrobial Resistance of Campylobacter Isolated During Commercial Broiler Production." Thesis, 2010. http://hdl.handle.net/1969.1/ETD-TAMU-2010-12-8643.

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Campylobacter jejuni is a commensal microorganism of the poultry gastrointestinal tract. Broilers, layers, ducks, turkeys, and quails can be colonized by Campylobacter without illness occurring. The vast majority of human Campylobacter infections are recognized as being foodborne. For 2008, preliminary FoodNet data showed that the Campylobacter incidence of infection, 12.68 per 100,000 of the U.S. population, is the second highest, only behind Salmonella at 16.20 per 100,000. To further understand Campylobacter’s role as a foodborne pathogen, analysis at the molecular level is needed. Microbia
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Chiang, ChenWei, and 江禎偉. "Study of Antibiotic Resistance and Epidemiological Typing of Staphylococcus aureus Isolated from Bovine Mastitis in Taiwan." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/54830440482404842138.

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碩士<br>國立中興大學<br>獸醫學系<br>93<br>Mastitis is considered to be the most frequent and most costly production disease in dairy herds. Furthermore, Staphylococcus aureus has been reported as one of the major contagious pathogen of bovine mastitis. A total of 2,586 raw milk samples from 26 dairy farms were analyzed in this experiment from November 2002 to March 2005 in Taiwan. The distributions of different microorganisms that isolated from raw milk were as followed: S. aureus 3.44%, coagulase-negative staphylococci 16.90%, Streptococcus spp. 9.90%, and coliforms 4.87%. For 89 S. aureus strains, there
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"Molecular mechanisms of antimicrobial resistance and population dynamics of Neisseria gonorrhoeae in Saskatchewan (2003-2011)." Thesis, 2013. http://hdl.handle.net/10388/ETD-2013-09-1181.

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Gonorrhea is caused by the human pathogen Neisseria gonorrhoeae. More than 106 million new cases of N. gonorrhoeae infections occur each year worldwide. There is no vaccine available against gonococcal infections and treatment of gonorrhea with antibiotics is the only way to eradicate infection. The high prevalence of antibiotic resistance (AMR) in this microorganism makes the effective treatment of gonococcal infections increasingly problematic. The emergence of AMR, especially to extended spectrum cephalosporins (i.e. cefixime and ceftriaxone) which are the last possibilities for single dose
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Yuan-Ti and 李原地. "A Study of Healthcare-associated Methicillin-resistant Staphylococcus aureus Forecasting Models at a Tertiary Care Hospital in Central Taiwan- the Trends, Correlation of Antimicrobial Consumption and Resistance, Time Series Analysis, and Molecular Typing." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/70642800716720579773.

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博士<br>中山醫學大學<br>醫學研究所<br>99<br>Background: The importance of methicillin-resistant Staphylococcus aureus (MRSA) infection antimicrobial resistance has increased rapidly during the last 15 years and has become a global health issue. MRSA infections have an enormous impact on the mortality and morbidity in the hospital settings. Objectives: (1) Study 1: The objective of study 1 is to use the correlation between antimicrobial consumption and antimicrobial resistance and apply the forecasting models performed time series analysis to explain the relationship antimicrobial consumption, infection con
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Woksepp, Hanna. "Individualized treatment and control of bacterial infections." Doctoral thesis, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-60191.

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Infectious diseases cause substantial morbidity and mortality, exacerbated by increasing antibiotic resistance. In critically ill patients, recent studies indicate a substantial variability in β-lactam antibiotic levels when standardized dosing is applied. New methods for characterizing nosocomial outbreaks of bacterial infections are needed to limit transmission. The goals of this thesis were to investigate new strategies towards individualized treatment and control of bacterial infections.  In Paper I we confirmed high variability in β-lactam antibiotic levels among intensive care unit (ICU)
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Beaudry, Ferland Michael. "Étude sur le Staphylococcus aureus résistant à la méthicilline chez le porc à l'abattoir au Québec, Canada." Thèse, 2011. http://hdl.handle.net/1866/6267.

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Le Staphylococcus aureus résistant à la méthicilline (SARM) est un pathogène important qui a été identifié comme agent d‟infection chez les animaux d‟élevage et les travailleurs exposés à ces animaux. Au Canada, très peu d‟informations sont disponibles concernant les SARMs d‟origine porcine. L‟objectif de cette étude était de déterminer la prévalence des SARMs provenant de porcs à l‟abattoir, de caractériser leur résistance aux antibiotiques ainsi que d‟évaluer le niveau de séroconversion des porcs envers le S. aureus chez les animaux porteurs ou non du SARM. Un total de 107 isolats ont été id
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Βενιέρη, Δανάη. "Προσδιορισμός της ανθρώπινης ή μη προέλευσης του κολοβακτηριδίου που απομονώνεται από το υδάτινο περιβάλλον με καλλιεργητικές και μοριακές τεχνικές". 2005. http://nemertes.lis.upatras.gr/jspui/handle/10889/381.

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Η διατήρηση της μικροβιολογικής ποιότητας του υδάτινου περιβάλλοντος είναι υψίστης σημασίας δεδομένων των κινδύνων που ενέχονται για τη δημόσια υγεία. Η αξιολόγηση της μικροβιολογικής ποιότητας των υδάτων πραγματοποιείται με την ανίχνευση της κοπρανώδους μόλυνσης και με τον έλεγχο της παρουσίας και συγκέντρωσης συγκεκριμένων μικροοργανισμών – δεικτών, όπως είναι η Escherichia coli. Ωστόσο, η απλή ανίχνευση κοπρανώδους μόλυνσης δεν επαρκεί για την υπόδειξη τρόπων εξυγίανσης και αντιμετώπισης του εκάστοτε προβλήματος. Οι δύο κύριες ομάδες στις οποίες διακρίνεται η κοπρανώδης μόλυνση είναι η ανθρ
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Chien, Hsin-I., and 錢欣儀. "Molecular typing of Methicillin-Resistant Staphylococcus aureus specimens from Southern Taiwan." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/52887704341833095612.

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碩士<br>國立中山大學<br>生物科學系研究所<br>101<br>A majority of the methicillin-resistant Staphylococcus aureus (MRSA) was thought as Healthcare-associated MRSA (HA-MRSA), which has been recognized as main causative agent of nosocomial infection. Contrarily, the community-associated MRSA (CA-MRSA) was reported that frequently isolated from skin and soft tissues in a hospital environment. In addition, these MRSA isolates usually expressed PVL gene (Panton-valentine leukocidin, PVL). In this study, we have collected 320 bacterial isolates comprised of pre-identified MRSA isolates from the specimens of patients
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Kamudumuli, Pocha Samuel. "Molecular typing of drug-susceptible-, mono-resistant-, multi-drug resistant- (MDR) and extensively-drug resistant- (XDR) Mycobacterium tuberculosis strains in Johannesburg." Thesis, 2015. http://hdl.handle.net/10539/17422.

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Chang, Wan-Ting, and 張菀庭. "Molecular Typing and Phenotypes Characterization of Methicillin-Resistant Staphylococcus aureus From Patients With Empyema Thoracis." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/91568985542732608941.

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碩士<br>中山醫學大學<br>生化暨生物科技研究所<br>101<br>Background: Staphylococcus aureus (S.aureus) can cause many serious infections, such as bacteremia, skin and soft tissue infections, pneumonia, osteoarthritis, and sepsis ,with high mortality rate and complication rate. Methicillin-Resistant S. aureus( MRSA) was discovered in the 1960s, has 60-80% of S. aureus belonging to MRSA in Taiwan. Literature has reported on Community- associated (CA-MRSA) and Healthcare- associated MRSA (HA-MRSA) is significantly different between genotyping and phenotype, and MRSA has a few specific clones in particular endemic. Th
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Bernier-Lachance, Jocelyn. "Prevalence et caracterisation de Staphylococcus aureus resistant a la methicilline d'origine aviaire au Quebec." Thèse, 2015. http://hdl.handle.net/1866/13374.

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Le Staphylococcus aureus résistant à la méthicilline (SARM) est un enjeu majeur en santé publique. Il est responsable d’une grande variété d’infections. Les “Livestock Associated-MRSA” (LA-MRSA) sont des SARM ayant comme origine les animaux de production tels le porc ou la volaille. Ils constituent un risque de transmission à l’humain via la chaîne alimentaire. Les LA-MRSA peuvent former du biofilm ce qui augmente leur tolérance aux stress environnementaux. Le biofilm est partiellement régulé par le système Agr. Il n’existe aucune donnée sur les ‘LA-MRSA’ d’origine aviaire au Québec. Les objec
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Wang, Wei-Yao, and 王唯堯. "Molecular Typing and Phenotype Characterization of Methicillin-Resistant Staphylococcus aureus Isolates from Osteoarticular Tissue and Blood in Taiwan." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/44661085299997485886.

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博士<br>國防醫學院<br>醫學科學研究所<br>100<br>Background: Staphylococcus aureus causes a variety of severe infections such as bacteremia, skin and soft tissue infection, pneumonia, osteoarticular infections, and sepsis. Methicillin-resistant S. aureus (MRSA) emerged since 1960s and accounted for 60-80% of S. aureus in Taiwan. Differences existed in molecular and phenotypic characters have been identified between community-associated MRSA (CA-MRSA) and hospital-associated MRSA (HA-MRSA). Limited MRSA clones were found to circulate worldwide and in certain geographic areas. The goals of this study were to de
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