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Dissertations / Theses on the topic 'Respiratory agents'

Author: Grafiati

Published: 4 June 2021

Last updated: 29 July 2024

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1

Marques, Gonçalo Nogueira. "Clinical approach to respiratory mucormycosis in a bottlenose dolphin (Tursiops truncatus) calf under human care." Master's thesis, Universidade de Lisboa, Faculdade de Medicina Veterinária, 2019. http://hdl.handle.net/10400.5/19336.

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Dissertação de Mestrado Integrado em Medicina Veterinária<br>Several fungi are described to cause invasive infections in dolphins, the respiratory system being a common site of involvement. Mucormycosis is considered one of the most devastating fungal infections in dolphins, associated with an elevated mortality rate, where hyphae are capable of invading blood vessels, producing tissue infarction and necrosis. A one-year-old male bottlenose dolphin (Tursiops truncatus) calf presented with a history of recurrent episodes of leukocytosis and occasional respiratory signs. During a routine faecal

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2

Tischer, Christina, Jan-Paul Zock, Maria Valkonen, Gert Doekes, Stefano Guerra, Dick Heederik, Deborah Jarvis, et al. "Predictors of microbial agents in dust and respiratory health in the Ecrhs." BioMed Central Ltd, 2015. http://hdl.handle.net/10150/610304.

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BACKGROUND: Dampness and mould exposure have been repeatedly associated with respiratory health. However, less is known about the specific agents provoking or arresting health effects in adult populations. We aimed to assess predictors of microbial agents in mattress dust throughout Europe and to investigate associations between microbial exposures, home characteristics and respiratory health. METHODS: Seven different fungal and bacterial parameters were assessed in mattress dust from 956 adult ECRHS II participants in addition to interview based home characteristics. Associations between micr

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3

FlorÃncio, Caroline Mary Gurgel Dias. "Nosocomial infection Childhood:he importance of respiratory viruses as agents of these diseases." Universidade Federal do CearÃ, 2014. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=12835.

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CoordenaÃÃo de AperfeÃoamento de Pessoal de NÃvel Superior<br>Nosocomial infections (NI) are a serious public health problem. Knowledge about the etiology of NI is important for the development of control measures, prevention and treatment. Viruses are important etiologic agent of NI has been studied in populations considered at risk as premature, heart disease, lung disease, and immunosuppressed. Respiratory hospital infection (RHI) generate discomfort to patients, postponing medical interventions, postoperative complications, use more drugs and, in some cases, intensive care, may progress to

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4

Du, Lanying. "Functional study of the spike protein of severe acute respiratory syndrome coronavirus." Click to view the E-thesis via HKUTO, 2007. http://sunzi.lib.hku.hk/hkuto/record/B38602362.

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5

Du, Lanying, and 杜蘭英. "Functional study of the spike protein of severe acute respiratory syndrome coronavirus." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B38602362.

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6

Zhang, Ke, та 张科. "Evaluation of anti-human respiratory syncytial virus effects of short interfering RNAs and β-defensin-4". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/209570.

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The human respiratory syncytial virus (hRSV) infection is a global public health burden in children aged under 2 years and immunocompromised or elderly adults. The choice for prophylaxis and therapy of hRSV infection was constrained to Palivizumab and Ribavirin. Therefore, this study aimed to develop effective anti-hRSV infection agents, such as short interfering RNA (siRNA) and β-defensin-4 (β-D-4). Since there still is no compatible animal model to evaluate antiviral effect of anti-hRSV agents, we first attempted to establish suitable animal model. A clinical isolate of hRSV (KI-RSV-W) wa

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7

Sethi, Sumanjit Kaur. "Rhinovirus infection of airway epithelial cells : focus on the major group receptor, intercellular adhesion molecule-1 (ICAM-1), and its regulation." Thesis, Keele University, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.242449.

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8

Yang, Li. "Studies on the effects of pharmacological agents on endotoxin induced pulmonary injury." Thesis, University of Hawaii at Manoa, 2003. http://proquest.umi.com/pqdweb?index=2&did=764805101&SrchMode=2&sid=10&Fmt=2&VInst=PROD&VType=PQD&RQT=309&VName=PQD&TS=1233179468&clientId=23440.

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9

Pham, Nhu-An. "Generation of oxidative stress by the respiratory chain following treatment with DNA damaging agents." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0003/MQ46064.pdf.

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10

Sans, Serramitjana Eulàlia. "Nanoencapsulated antimicrobials to fight Pseudomonas aeruginosa respiratory infections in cystic fibrosis patients: a promising strategy." Doctoral thesis, Universitat de Barcelona, 2017. http://hdl.handle.net/10803/461914.

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P. aeruginosa is one of the major opportunistic pathogen colonizing the respiratory tract of cystic fibrosis (CF) patients and causing chronic airways infection. Once P.aeruginosa established chronically in the CF lung, bacterial density increases and the microorganism switches to a mucoid form and to a stable biofilm mode of growth in which susceptibility to antimicrobials decreases. The high resistance of P.aeruginosa to multiple antimicrobials led to scenarios in which almost no treatment options are available. In this regard, the research on the introduction of less toxic antimicrobials as

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11

Falcone, Pin Bruno Nicolás. "Physicochemical properties of inhalation drugs." Thesis, University of Cambridge, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.648175.

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12

Hiriote, Wanwarang. "Mechanisms of resistance for human respiratory syncytial virus isolates against anti-fusion agents in tissue culture." Thesis, University of Newcastle Upon Tyne, 2012. http://hdl.handle.net/10443/1683.

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Human respiratory syncytial viruses (hRSV) are a major cause of lower respiratory tract disease on primary infection of infants and children. There is no effective vaccine against the virus, but high risk infants can be protected by administration of palivizumab (PZ), a humanised anti-fusion glycoprotein. In previous studies, hRSV isolated from the naso-pharyngeal secretions of infected infants were found to be dominated by slow growing variants which were largely refractory to neutralization by PZ. On further passage in tissue culture, the slow growing variants were replaced by fast growing,

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13

Webster, Richard Ian School of Women &amp Children's Health UNSW. "Respiratory function as a measure of muscle strength in young boys with Duchenne Muscular Dystrophy." Awarded by:University of New South Wales. School of Women and Children's Health, 2003. http://handle.unsw.edu.au/1959.4/19206.

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AIMS: To evaluate the use of Manual Muscle Strength Tests (MMST), Timed Functional Tests (TFT) and Respiratory Function Tests (RFT) as measures of muscle strength in young boys with Duchenne Muscular Dystrophy (DMD) and specifically to evaluate the use of Peak Expiratory Flow (PEF). BACKGROUND: There is a need to measure the effect of treatments that potentially increase muscle strength in DMD. PEF may have advantages over Vital Capacity (VC) as a measure of respiratory function in young boys with DMD. METHODS: 17 boys with DMD (aged 5-10 years) were assessed regularly over one year. Assessmen

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14

Dowling, Ruth Brigid. "The influence of pharmacological agents on Pseudomonas aeruginosa and Haemophilus influenzae infection of the respiratory mucosa in vitro." Thesis, Imperial College London, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.300382.

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15

Machado, de Carvalho Liliana Sofia. "Study of the expression and regulation of the autocrine loop components of the cyclooxygenase pathway and their implication in aspirin exacerbated respiratory disease." Doctoral thesis, Universitat de Barcelona, 2015. http://hdl.handle.net/10803/396213.

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Aspirin exacerbated respiratory disease (AERD) is a clinical syndrome characterized by the combination of nasal polyps (NPs), chronic hypertrophic eosinophilic sinusitis, asthma and severity to any medication that inhibits cyclooxygenase (COX)-1 enzymes, namely aspirin and other non-steroidal anti-inflammatory drugs. AERD is characterized by intense inflammation of the respiratory mucosa, with large number of activated tissue eosinophils, mast cells, monocytes, and neutrophils. The persistent inflammation likely contributes to the recurrent development of severe nasal polyposis. The pathoge

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Saiki-Macedo, Stephanie, Jorge Valverde-Ezeta, Angela Cornejo-Tapia, Maria Esther Castillo, Verónica Petrozzi-Helasvuo, Miguel Angel Aguilar-Luis, Valle Luis J. Del, et al. "Identfication of viral and bacterial etiologic agents of the pertussis-like syndrome in children under 5 years old hospitalized." BioMed Central Ltd, 2019. http://hdl.handle.net/10757/652471.

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Background: Acute respiratory infections (ARIs) represent an important cause of morbidity and mortality in children, remaining a major public health concern, especially affecting children under 5 years old from low-income countries. Unfortunately, information regarding their epidemiology is still limited in Peru. Methods: A secondary data analysis was performed from a previous cross-sectional study conducted in children with a probable diagnosis of Pertussis from January 2010 to July 2012. All samples were analyzed via Polymerase Chain Reaction (PCR) for the following etiologies: Influenza-A,

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17

Johns, Rachel Elizabeth. "Delivery of anti-inflammatory nucleic acid therapeutics using smart polymeric carriers /." Thesis, Connect to this title online; UW restricted, 2007. http://hdl.handle.net/1773/8080.

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18

Amalfi, Liliam Machado. "Perfil microbiologico de pacientes com fibrose cistica." [s.n.], 2007. http://repositorio.unicamp.br/jspui/handle/REPOSIP/308366.

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Orientador: Antonio Fernando Ribeiro<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas<br>Made available in DSpace on 2018-08-11T18:35:30Z (GMT). No. of bitstreams: 1 Amalfi_LiliamMachado_M.pdf: 5120878 bytes, checksum: c21489142714302bf486eaaa938cf04c (MD5) Previous issue date: 2007<br>Resumo: Considerando que a fibrose cística é a mais importante doença hereditária, potencialmente letal, incidente na raça branca, que a infecção pulmonar é reconhecida por ter o maior papel na morbimortalidade levando à morte prematura em 90% dos pacientes, e que a

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19

Smith, Johan. "A comparison of synthetic surfactants : evaluation of a novel surfactant (1,2-dipalmitoyl-sn-phosphatidycholine and trehalose [C12H22O11]) and comparison with other synthetic formulations." Thesis, Stellenbosch : Stellenbosch University, 2002. http://hdl.handle.net/10019.1/52624.

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In title 12, 22, 11 are in subscript.<br>Thesis (PhD)--Stellenbosch University, 2002.<br>ENGLISH ABSTRACT: The aim of this study was to test a synthetic protein-free surfactant preparation, LPM-l, with the same chemical composition as commercially available Exosurf (Glaxo Wellcome), but containing in addition, a sugar, trehalose (TRE). Towards this end, a study was designed to firstly test the hypothesis that the true difference in acute physiological effects between a mixture of oppe, tyloxapol, hexadecanol and trehalose (LPM-l), and Exosurf, (Oppe, tyloxapol and hexadecanol) is zero, i

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20

Wang, Wei. "Establishment of Highly Sensitive Monitoring System of Causative Agents in Acute Respiratory Infection in Children and Emergence of New Variants and of Epidemics in Shanghai, China." Paris 7, 2010. http://www.theses.fr/2010PA077248.

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Les infections aiguës des voies respiratoire inférieures (ALRI) sont un problème persistant et dominant de santé publique. De nombreux virus peuvent causer une ALRI, y compris le virus respiratoire syncitial, le virus de la grippe, le virus parainfluenza, le rhinovirus, l'enterovirus, l'adénovirus et le coronavirus. Depuis l'épidémie de SRAS en 2004 et les épidémies récentes de grippe aviaire H5N1 hautement pathogène, la transmission des virus zoonotiques à l'homme pose un problème majeur de santé publique, car les contacts rapprochés entre l'animal et l'homme ou entre les hommes faciliteraien

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21

Wang, Jianpu. "Pathophysiology and treatment of chlorine gas-induced lung injury : an experimental study in pigs /." Linköping : Univ, 2004. http://www.bibl.liu.se/liupubl/disp/disp2004/med877s.pdf.

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22

Sandek, Karin. "Ventilation-perfusion relationships and respiratory drive in chronic obstructive pulmonary disease : with special reference to hypoxaemia, sleep quality and treatment with inhaled corticosteroid /." Stockholm, 2002. http://diss.kib.ki.se/2002/91-628-5274-4.

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23

Song, Zehua. "Agents antimicrobiens ciblant le complexe III de la chaine respiratoire mitochondriale : Etudes des déterminants structuraux de la sensibilité différentielle et du développement de la résistance, en utilisant la levure comme organisme modèle." Thesis, Université Paris-Saclay (ComUE), 2016. http://www.theses.fr/2016SACLS281/document.

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Le complexe bc₁ de la chaîne respiratoire mitochondriale est une bonne cible thérapeutique pour traiter le paludisme car cette enzyme est essentielle au parasite. Ses deux sites actifs, Qo et Qi, formés par le cytochrome b, ne sont pas totalement conservés entre les espèces, facilitant la découverte d’inhibiteurs à affinité différentielle, ce qui est important dans le développement de médicaments. L’atovaquone est le seul antipaludique ciblant le complexe bc₁ utilisé en médecine. L’émergence de résistance rend urgente l’étude de nouveaux inhibiteurs. Les ELQs (Endochin-like Quinolones) sont un

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24

Muchão, Fabio Pereira. "Avaliação da eficácia e segurança de doses crescentes de salbutamol, administrado através de inalador dosimetrado, em crianças e adolescentes com crise de asma." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/5/5141/tde-06022017-151909/.

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INTRODUÇÃO: A dosagem ideal de salbutamol através de inaladores dosimetrados para o tratamento da asma aguda na infância não está bem estabelecida. Este estudo visou comparar dois regimes de dosagem de salbutamol via inalador dosimetrado com espaçador em crianças com crises moderadas ou graves de asma. As hipóteses deste estudo foram: I. Pacientes em vigência de crises de sibilância moderadas ou graves necessitam doses de salbutamol maiores que as até recentemente recomendadas pelo Global Initiative for Asthma (GINA). II. Doses maiores de salbutamol são seguras para crianças com idade igual ou

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André, Malin. "Rules of thumb and management of common infections in general practice /." Linköping : Univ, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-5183.

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26

Martini, Matheus Cavalheiro 1983. "Avaliação in vitro da atividade antiviral de extratos de plantas frente ao metapneumovirus aviário (AMPV) e vírus respiratório sincicial bovino (BRSV)." [s.n.], 2010. http://repositorio.unicamp.br/jspui/handle/REPOSIP/317444.

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Orientadores: Clarice Weis Arns, Luciana Konecny Kohn<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-08-16T18:01:14Z (GMT). No. of bitstreams: 1 Martini_MatheusCavalheiro_M.pdf: 571995 bytes, checksum: 52ec8a0bed8fa3efd4434ec2a2e6a100 (MD5) Previous issue date: 2010<br>Resumo: Para avaliar a atividade antiviral dos extratos de plantas brasileiras foram eleitos o Metapneumovirus aviário (aMPV) e o vírus Respiratório sincicial bovino (BRSV) pertences à família Paramyxoviridae, subfamília Pneumovirinae, gêneros Metapneumo

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Naves, Kattia Cristina. "Análise crítica do tratamento instituído a crianças com infecção por vírus sincicial respiratório em um hospital público." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/5/5141/tde-14082018-102623/.

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Introdução: A bronquiolite aguda é a principal causa de internação de lactentes menores de um ano de idade e tem como principal agente etiológico o vírus sincicial respiratório. As principais diretrizes baseadas em evidências recomendam o tratamento de suporte com hidratação e oxigenoterapia, quando necessário e não indicam o uso rotineiro de corticosteroides, broncodilatadores e antibióticos. No entanto, estudos anteriores mostraram que o uso inadvertido dessas medicações é frequente na prática clínica. Objetivo: Analisar o tratamento aplicado a lactentes com bronquiolite viral aguda em um ho

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28

Borko, Milanović. "Uticaj šestomesečne inhalatorne kortikosteroidne terapije na vrednosti interleukina-33 u serumu kod dece sa alergijskom astmom." Phd thesis, Univerzitet u Novom Sadu, Medicinski fakultet u Novom Sadu, 2019. https://www.cris.uns.ac.rs/record.jsf?recordId=108237&source=NDLTD&language=en.

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Uvod: Interleukin 33 (IL-33) ima značajnu ulogu u inflamatornim i autoimunskim oboljenjima, ali se sve vi&scaron;e proučava njegov značaj u imunopatogenezi različitih alergijskih oboljenja, uključujući i alergijsku astmu (AA). Cilj: Ispitivanje vrednosti IL-33 u serumu pacijenata sa AA pre i posle &scaron;estomesečne inhalatorne kortikosteroidne terapije (ICS Th) i povezanosti dobijenih vrednosti IL-33 sa određenim kliničkim i laboratorijskim karakteristikama ovih pacijenata. Metode: Vrednost IL-33 u serumu određena je kod 61 pacijenta sa AA pre započinjanja i posle sprovedne &scaron;estomeseč

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29

Freddi, Norberto Antonio. ""Avaliação dos efeitos da adição do polietilenoglicol ao surfactante pulmonar exógeno na função pulmonar, em um modelo experimental de síndrome de desconforto respiratório tipo agudo"." Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/5/5141/tde-20042006-111715/.

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O surfactante pulmonar é uma substância fundamental na mecânica pulmonar, com atividade biofísica e de proteção alveolar por reduzir a tensão superficial e impedir o seu colabamento.Na síndrome do desconforto respiratório tipo agudo(SDRA) ocorre uma diminuição quantitativa e disfunção qualitativa do surfactante com agravamento do quadro clínico.Estudamos, em um modelo experimental de SDRA em coelho adulto, os efeitos da adição de polietilenoglicol ao surfactante pulmonar exógeno quanto à melhora da complacência pulmonar,pressão ventilatória,índice de oxigenação,diferença alvéolo-arterial de ox

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Kang, Li. "Marketing strategy of establishing a brand of cold & flu medicine in China OTC market." Thesis, University of Macau, 2001. http://umaclib3.umac.mo/record=b1636651.

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Domínguez, Fandos David. "Estudio de los efectos de agentes anticolinérgicos y de inhibidores de fosfodiesterasa-5 sobre la estructura pulmonar en un modelo experimental de enfermedad pulmonar obstructiva crónica inducido por humo de tabaco en el cobayo." Doctoral thesis, Universitat de Barcelona, 2015. http://hdl.handle.net/10803/293379.

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La enfermedad pulmonar obstructiva crónica (EPOC) es una patología prevenible caracterizada por una limitación al flujo aéreo progresiva y no completamente reversible, disnea, producción de esputo y tos crónica. La obstrucción al flujo aéreo se asocia a un proceso inflamatorio crónico en la vía aérea y el parénquima pulmonar en respuesta a partículas nocivas o gases inhalados, en particular al humo de cigarrillo (HC) (Figura. Esta respuesta inflamatoria crónica puede inducir la destrucción del parénquima pulmonar o enfisema y alteraciones estructurales de la vía aérea pequeña al alterar los

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Silva, Maristela Prado e. "Efeitos da imunossupressão sobre a depuração mucociliar de ratos: comparação entre dois esquemas de terapia tríplice." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/5/5156/tde-20062016-093503/.

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INTRODUÇÃO: O transplante de pulmão é parte fundamental no tratamento das doenças terminais do pulmão, constituindo uma modalidade terapêutica eficaz para pacientes com doença pulmonar incapacitante, progressiva e em estágio final. No entanto, as drogas imunossupressoras usadas para evitar a rejeição do enxerto podem causar efeitos colaterais em diversos tecidos. O sistema mucociliar, presente nas vias aéreas, é um dos principais mecanismos de defesa do trato respiratório e pode ser alterado por ação das drogas imunossupressoras. Desta forma, o objetivo deste estudo foi avaliar o sistema mucoc

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Reginatto, Renato de Matteo. "Um ensaio teórico sobre a geografia da saúde e a questão do ar como agentes de influência na soberania nacional /." Rio Claro : [s.n.], 2009. http://hdl.handle.net/11449/95632.

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Orientador: Sandra Elisa Contir Pitton<br>Banca: Ari Menardi Junior<br>Banca: Lucy Marion Calderini Philadelpho Machado<br>Resumo: O trabalho científico em questão buscou de um modo claro, unir todas as nuances relevantes ao tema proposto, mesclando Geografia, Medicina e Direito, numa redação coesa e enriquecida com dados estatísticos e muita discussão teórica. Inicialmente, discutiu-se questões preliminares da Geografia da Saúde, pontuando observações terminológicas e metodológicas, consagrando assim uma ruptura institucional com antigas formas de produção científica. Num segundo plano, desta

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Souvestre, Marie. "Étude du statut sanitaire des élevages avicoles familiaux et de loisir et évaluation de leur rôle à l'interface avec les élevages avicoles commerciaux en France." Thesis, Toulouse 3, 2021. http://www.theses.fr/2021TOU30069.

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Les élevages avicoles familiaux tels que les basses-cours rurales, les poulaillers urbains et les élevages de volailles de loisir sont un secteur important de la production avicole française. Estimés à 2,5 millions de propriétaires à ce jour, ces élevages sont suspectés de pouvoir transmettre des agents pathogènes aux élevages avicoles commerciaux. Dans cette étude, nous avons étudié le rôle des élevages avicoles familiaux dans la circulation et la transmission d'agents pathogènes aux élevages avicoles commerciaux. Afin de mieux caractériser les acteurs de la filière avicole familiale, une enq

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Martinelli, M. "SORVEGLIANZA DELLE INFEZIONI RESPIRATORIE ACUTE (ARI): APPROCCI INNOVATIVI PER L'IDENTIFICAZIONE E LA CARATTERIZZAZIONE DEGLI AGENTI VIRALI COINVOLTI." Doctoral thesis, Università degli Studi di Milano, 2014. http://hdl.handle.net/2434/232585.

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Surveillance of acute respiratory infections (ARI): innovative approaches for the identification and characterization of viral agents Introduction. Acute respiratory infections (ARI) are ubiquitous, air-borne transmitted and highly contagious infections, characterized by typical epidemic pattern. Though ARI causative agents may be bacterial or viral, viruses are by far the most common causes of ARI. In recent years, the global epidemiological scenario has been enlivened by the identification and emergence of many airborne pathogens (such as influenza viruses A/H5N1, A/H7N7, A/H7N9, corona

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Martínez, Antón Mª Asunción. "Mucus Hypersecretion, MUC genes and Mucins in Inflammatory Nasosinusal Diseases. Regulation by Proinflammatory and Antiinflammatory Agents." Doctoral thesis, Universitat de Barcelona, 2008. http://hdl.handle.net/10803/2255.

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The overall objectives of this thesis are: one, characterize the expression of mucin at baseline human nasal mucosa in healthy and inflamed (nasal polyps), and two, to analyze the expression of mucin and the regulation exerted by glucocorticoids on it in patients with nasal polyposis ( "in vivo") and a respiratory cell line (in vitro).<br><i>D'entre totes les estructures que composen el tracte respiratori, el nas, a través de la mucosa nasal, és l'òrgan encarregat de la preparació del moc inhalat mitjançant la filtració, l'escalfament i la humidificació d'aquest abans que arribi als pulmons, e

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Reginatto, Renato de Matteo [UNESP]. "Um ensaio teórico sobre a geografia da saúde e q questão do ar como agentes de influência na soberania nacional." Universidade Estadual Paulista (UNESP), 2009. http://hdl.handle.net/11449/95632.

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Made available in DSpace on 2014-06-11T19:27:51Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-10-23Bitstream added on 2014-06-13T20:36:22Z : No. of bitstreams: 1 reginatto_rm_me_rcla.pdf: 6179266 bytes, checksum: b72d6385da3f3404c5162e241fe85718 (MD5)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>O trabalho científico em questão buscou de um modo claro, unir todas as nuances relevantes ao tema proposto, mesclando Geografia, Medicina e Direito, numa redação coesa e enriquecida com dados estatísticos e muita discussão teórica. Inicialmente, discutiu-se ques

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Dunn, Melinda Carol Cox. "Inhibition of Respiratory Syncytial Virus In Vitro and In Vivo by the Experimental Immunosuppressive Agent Leflunomide." The Ohio State University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=osu1269449453.

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Parisey, Nicolas. "Modélisation et simulation multi-agents de phénomènes d'oxydo-réduction : application au complexe III de la chaîne respiratoire." Bordeaux 2, 2007. http://www.theses.fr/2007BOR21451.

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Les mouvements de larges sous-unités protéiques sont très importants dans la liaison des substrats et les propriétés catalytiques des enzymes. Le but de notre étude a été de combiner la modélisation des réactions d'oxydo-réduction et les changements de conformations des complexes enzymatiques redox afin de décrire la dynamique réactionnelle de ces complexes. Nous avons réutilisé des algorythmes précédemment décrits dans la littérature afin de déterminer les changements conformationnels au sein des complexes redox. Nous avons ensuite développé un Système Multi-Agent permettant la simulation des

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Segalés, Coma Joaquim. "Síndrome respiratorio y reproductivo porcino: interacción con el agente causal de la enfermedad de Glässer." Doctoral thesis, Universitat Autònoma de Barcelona, 1996. http://hdl.handle.net/10803/5610.

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EN EL PRESENTE TRABAJO SE DESCRIBEN LOS EXPERIMENTOS REALIZADOS CON EL OBJETO DE DEMOSTRAR LA EXISTENCIA O NO DE UNA ASOCIACION ENTRE EL PRRSV Y H. PARASUIS. PARA ELLO SE HAN REALIZADO ESTUDIOS TANTO IN VIVO COMO IN VITRO, HACIENDO HINCAPIE EN LOS ESTUDIOS PATOLOGICOS Y DE PATOGENIA EN LOS PRIMEROS, Y ULTRAESTRUCTURALES Y FUNCIONALES EN LOS SEGUNDOS. SE REALIZARON 3 EXPERIMENTOS CON ANIMALES CON EL OBJETO DE DILUCIDAR SI LA PRESENCIA PEVIA DE PRRSV PROVOCABA UN AUMENTO EN LA PREVALENCIA DE POLISEROSITIS FIBRINOSA EN LOS ANIMALES INOCULADOS POSTERIORMENTE CON H. PARASUIS (EXPERIMENTOS 1 Y 3), Y

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Roux, Xavier Pierre Marie. "Développement d'un vaccin contre le virus respiratoire syncytial, agent de la bronchite du nouveau- né : analyse des réponses immunitaires au niveau du tractus respiratoire." Versailles-St Quentin en Yvelines, 2007. http://www.theses.fr/2007VERS0007.

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The respiratory syncytial virus is the main causative agent of bronchiolitis during infancy. During my thesis, I have evaluated in mice a novel subunit vaccine based on the nasal delivery of the viral nucleoprotein (N SRS). Adult responses primed by N SRS immunization were protective against an experimental viral challenge. However, when administered to neonates, this vaccine caused an immunopathologic Th2 immune response characterized by lung eosinophilia. In order to decipher the mechanisms leading to lung immunity in neonates, I have compared the activation and polarization of neonatal vers

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Capelozzi, Marco Antonio. ""Determinantes funcionais e morfológicos de ação de droga sobre os pulmões utilizando um modelo experimental em cobaias sob uso do cloridrato de fluoxetina"." Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/5/5144/tde-29092005-155733/.

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Muito se tem pesquisado sobre os efeitos adversos dos antidepressivos tricíclicos (p.e. imipramina) sobre o sistema respiratório, embora pouco ou quase nada se encontre com relação a tal aspecto na literatura médica sobre a fluoxetina (Prozac®) um inibidor seletivo da recaptação de serotonina, até porque esta droga começou a ser utilizada somente há cerca de quinze anos. Ambas substâncias (fluoxetina e imipramina, ou seus congêneres) agem basicamente sobre quadros depressivos, fóbicos e obsessivo-compulsivos, obesidade, anorexia, e outras indicações de várias naturezas, indo desde a ansiedade

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Saiki, Macedo Stephanie Alejandra, and Ezeta Jorge Valverde. "Identification of viral and bacterial etiologic agents of the Pertussis-like syndrome in children under 5 years old hospitalized." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2018. http://hdl.handle.net/10757/624878.

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Objective: To study the presence of 8 respiratory viruses (Influenza-A, Influenza-B, RSV-A, RSV-B, Adenovirus, Parainfluenza-1, Parainfluenza-2 and Parainfluenza-3) and atypical bacteria (Mycoplasma pneumonia and Chlamydia pneumonia) in samples from Peruvian children under 5 years-old previously analyzed for Bordetella. Pertussis. Methods: A secondary data analysis was performed from a previous cross-sectional study conducted in children with a probable diagnosis of Pertussis from January 2010 to July 2012. All samples were analyzed via Polymerase Chain Reaction (PCR) for the following etiolog

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Vallières, Cindy. "Agents antimicrobiens ciblant le complexe III de la chaîne respiratoire mitochondriale : caractérisation de nouveaux inhibiteurs et étude du développement des résistances." Phd thesis, Université Paris Sud - Paris XI, 2012. http://tel.archives-ouvertes.fr/tel-00840029.

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Des inhibiteurs du complexe bc1 de la chaîne respiratoire mitochondriale ont été développés comme agents antimicrobiens pour lutter contre des pathogènes de l'Homme et de plantes. Ces drogues ciblent les poches catalytiques Qo et Qi formées par le cytochrome b. La comparaison de séquences de cette protéine montre que les sites Qo et Qi sont bien conservés entre les organismes mais qu'il existe toutefois des variations qui pourraient expliquer leur différence de sensibilité aux drogues. A l'aide du modèle levure S. cerevisiae, nous avons étudié les déterminants de la résistance/sensibilité natu

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Paiva, Ramon Evangelista dos Anjos. "A busca de sintom?ticos respirat?rios de tuberculose na pr?tica e perspectiva do agente comunit?rio de sa?de nos distritos sanit?rios de Natal." Universidade Federal do Rio Grande do Norte, 2010. http://repositorio.ufrn.br:8080/jspui/handle/123456789/14722.

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Made available in DSpace on 2014-12-17T14:46:47Z (GMT). No. of bitstreams: 1 RamonEAP_DISSERT.pdf: 1410551 bytes, checksum: dfe074204e595b296e1933aa794efa40 (MD5) Previous issue date: 2010-09-24<br>Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico<br>The objective of this work - which is characterized analyze the search for symptomatic tuberculosis in practice and perspective of the Community Health Agent (ACS) in the districts of Natal. Methods: This is a cross-sectional study. The study population was 646 professionals, and conducted a probabilistic random sampling, stratified

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Canello, Vinícius Athaydes. "Marcadores do equilíbrio oxidativo e celularidade do lavado broncoalveolar de equinos mantidos em baias com dois tipos de cama e a pasto e identificação de agentes fúngicos das camas e do feno /." Jaboticabal, 2017. http://hdl.handle.net/11449/149864.

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Orientador: José Corrêa de Lacerda Neto<br>Banca: Raquel Micarelli Albernaz<br>Banca: Gustavo Garkalns de Souza Oliveira<br>Banca: Kamila Gravena<br>Banca: Daniela Gomes da Silva<br>Resumo: O grande desafio do sistema de defesa respiratório é a manutenção dos animais em baias. Pois, devido a diversos fatores, acaba por aumentar as chances do desenvolvimento de afecções respiratórias e a qualidade do material utilizado como cama é fator agravante. Diante disto, três grupos com 5 equinos cada foram submetidos a 45 dias sob o mesmo manejo, sendo dois grupos estabulados com diferentes tipos de cam

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Canello, Vinícius Athaydes [UNESP]. "Marcadores do equilíbrio oxidativo e celularidade do lavado broncoalveolar de equinos mantidos em baias com dois tipos de cama e a pasto e identificação de agentes fúngicos das camas e do feno." Universidade Estadual Paulista (UNESP), 2017. http://hdl.handle.net/11449/149864.

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Submitted by VINÍCIUS ATHAYDES CANELLO null (vinaocanello@hotmail.com) on 2017-03-16T11:28:58Z No. of bitstreams: 1 Tese Versão Final.pdf: 4376586 bytes, checksum: 13d4cc1c29f43d7c4deb2102a7b48543 (MD5)<br>Approved for entry into archive by Juliano Benedito Ferreira (julianoferreira@reitoria.unesp.br) on 2017-03-22T16:42:38Z (GMT) No. of bitstreams: 1 canello_va_dr_jabo.pdf: 4376586 bytes, checksum: 13d4cc1c29f43d7c4deb2102a7b48543 (MD5)<br>Made available in DSpace on 2017-03-22T16:42:38Z (GMT). No. of bitstreams: 1 canello_va_dr_jabo.pdf: 4376586 bytes, checksum: 13d4cc1c29f43d7c4deb2102a

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Pasquier, Christophe. "Influence de la composition des exopolysaccharides de Pseudomonas aeruginosa sur l'adhésion de cet agent aux cellules de l'épithélium respiratoire et sur les fonctions effectrices des macrophages." Toulouse 3, 1997. http://www.theses.fr/1997TOU30086.

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L'apparition de souches muqueuses de pseudomonas aeruginosa, par production d'exopolysaccharides, est responsable du passage a la chronicite des infections a p. Aeruginosa et de l'echec therapeutique. La composition de ces exopolysaccharides, riches en alginate, est heterogene et pourrait expliquer les differences de comportement des souches productrices vis-a-vis des reponses de l'hote. Pour aborder ce probleme, nous avons choisi d'etudier le role de la composition chimique de ces exopolysaccharides a deux niveaux : (1) l'adhesion de p. Aeruginosa aux cellules de l'epithelium respiratoire et

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Blanco, Vich Isabel. "Estudio de los efectos de los agentes vasodilatadores sobre el intercambio de gases y la hemodinámica pulmonar, en las enfermedades respiratorias crónicas." Doctoral thesis, Universitat de Barcelona, 2011. http://hdl.handle.net/10803/31995.

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La hipertensión pulmonar (HP) es una de las complicaciones más relevantes de las enfermedades respiratorias crónicas, especialmente en la historia natural de la enfermedad pulmonar obstructiva crónica (EPOC) y en las enfermedades pulmonares intersticiales difusas (EPID), más concretamente en la fibrosis pulmonar idiopática (FPI). Es bien conocido que su presencia se asocia a una supervivencia menor y a una mayor utilización de recursos sanitarios. La prevalencia de HP en las enfermedades respiratorias no es insignificante, se estima entorno el 50% o incluso en un porcentaje mayor en los pacien

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Valdivia, Rozas Christian Benito. "Infecciones respiratorias bajas por agentes virales : aspectos clínico, epidemiológicos y evolución en el servicio de pediatría del Hospital Nacional Daniel Alcides Carrión-Callao 2006-2007." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2010. https://hdl.handle.net/20.500.12672/15240.

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Estudia los aspectos clínico-epidemiológicos de las infecciones respiratorias bajas por agentes virales en el Servicio de Pediatría del Hospital Nacional Daniel Alcides Carrión-Callao, en el periodo 2006-2007. Las infecciones respiratorias agudas bajas (IRAB) representan un problema prioritario de salud a nivel mundial, consideradas como las de más alta prevalencia, tienen un gran impacto en las tasas de morbimortalidad infantil. A nivel internacional existen numerosos estudios epidemiológicos referentes a etiología y estacionalidad en IRA, con escasos estudios en países en vías de desarrollo

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