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Dissertations / Theses on the topic 'Respiratory parameters of lung'

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Published: 28 June 2021
Last updated: 29 July 2025

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1

Ganzert, Steven [Verfasser]. "Data Analysis in respiratory physiology : Model detection, parameter extraction and prediction methods for lung protective ventilation / Steven Ganzert." Mainz : Universitätsbibliothek Mainz, 2016. http://d-nb.info/110017768X/34.

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2

Radicioni, Erika. "L'efficacia della fisioterapia respiratoria sui parametri polmonari e funzionali nei pazienti con Spondilite Anchilosante: revisione della letteratura." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2020. http://amslaurea.unibo.it/21951/.

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Background: la spondilite anchilosante (SA) è una patologia infiammatoria sistemica cronica ad evoluzione progressiva ed anchilosante che colpisce principalmente le articolazioni sacro-iliache e lo scheletro assiale. Sono frequenti manifestazioni extra-articolari a livello polmonare, con quadri respiratori restrittivi e ridotta capacità funzionale. Il trattamento convenzionale prevede esercizi di mantenimento del ROM e allungamento muscolare. Ad oggi non sono presenti studi a sufficienza sul miglioramento della funzione polmonare e della capacità di esercizio in questi pazienti. Obiettivo: v
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3

Chacón-Chaves, Ronald Alfredo. "Respiratory function after lung transplantation." Thesis, University of Newcastle upon Tyne, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.247836.

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4

Heeley, Emma Louise. "Lung surfactant and secretory phospholipase A←2 in inflammatory lung disorders." Thesis, University of Southampton, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.323970.

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5

Collier, Clare Georgina. "Factors affecting lung clearance kinetics." Thesis, Open University, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.253714.

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6

Ward, Katie. "Respiratory impairment in stroke patients : lung function, respiratory muscles, voluntary and reflex cough." Thesis, King's College London (University of London), 2012. https://kclpure.kcl.ac.uk/portal/en/theses/respiratory-impairment-in-stroke-patients(25ebe631-2023-4477-89fc-2e3162303e95).html.

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Stroke is a major public health problem and stroke patients suffer much mortality and morbidity due to chest infections, especially in the acute period. Chest infections are associated with respiratory muscle weakness and poor cough. We studied ischaemic hemispheric stroke patients within two weeks of their first-ever stroke to investigate their respiratory physiology, volitional and non-volitional respiratory muscle strength and voluntary and reflex cough function. -- Patients were weak on voluntary but not involuntary tests of expiratory muscle function. They were also impaired on tests of b
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7

Barry, Simon Mark Elliot. "Lymphocyte responses to respiratory pathogens in the lung." Thesis, University College London (University of London), 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.409576.

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8

Rocksʹen, David. "Acute lung injury : study of pathogenesis and therapeutic interventions /." Umeå : Univ, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-161.

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9

Bedford, Laura Elizabeth. "The emotional impact of screening for lung cancer." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/47077/.

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Lung cancer is the most commonly diagnosed cancer and the most common cause of cancer related death worldwide. Population-based lung cancer screening programmes have been initiated in the USA and could soon be implemented in other countries. The overarching purpose of this thesis was to explore the emotional impact of lung cancer screening. The research was conducted as part of a clinical trial that was investigating the effectiveness of a blood autoantibody test, EarlyCDT®-Lung, in identifying individuals at the risk of lung cancer. A systematic review was conducted that aimed to identify fac
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10

Hale, Tudor. "Lung gas mixing efficiency in exercise." Thesis, University of Surrey, 1987. http://epubs.surrey.ac.uk/842928/.

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The aim of this thesis was to examine the effects of exercise on gas mixing in the lung during exercise. There were four major stages. Firstly, the existing equipment used with resting subjects was applied to the exercising subject and was found to be inappropriate. Secondly, an in-line system of measuring flow and gas concentration was devised. Thirdly this system was validated with the aid of a physical model and resting subjects. Finally, nitrogen wash-out data were collected from 24 subjects at rest and during progressive exercise at three standard exercise intensities. The dynamic respons
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11

Hulse, Elspeth Joy. "Respiratory complications of organophosphorus pesticide poisoning." Thesis, University of Edinburgh, 2016. http://hdl.handle.net/1842/25881.

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Of the 800,000 suicides recorded globally every year, over a third are due to pesticide ingestion, the majority of which occur in rural Asia with organophosphorus (OP) compounds. These anticholinesterase pesticides cause an acute cholinergic syndrome characterised by decreased consciousness, excessive airway secretions and respiratory failure. A combination of these clinical features is the most common cause of death. Up to 30% of OP pesticide poisoned patients are admitted to the Intensive Care Unit (ICU) for tracheal intubation and lung ventilation, but up to half die. It is not understood w
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12

Jiménez, Luis Albert. "Signalling mechanisms induced by particulate matter in lung cells." Thesis, Edinburgh Napier University, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.250084.

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13

Al-Ahmad, Abdullmohsen Mohammed. "Airway pressure release ventilation mode in lung injury." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/44246/.

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Airway pressure release ventilation (APRV) is a promising, unconventional mode of ventilation for the treatment of various respiratory diseases, including acute respiratory distress syndrome (ARDS). However, despite increasing global use and reported advantages of APRV over other modes, definitive conclusions cannot be drawn due to several concerns. First, the major confusion between APRV and other, similar modes, such as bi-phasic positive airway pressure (BIPAP). Second, clinical and methodological heterogeneity among published studies of APRV are understandably extensive, which contributes
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14

Smith, Emilee. "Lung function in healthy South African adult females." Master's thesis, University of Cape Town, 2015. http://hdl.handle.net/11427/15740.

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Background: Accurate and appropriate spirometry reference values allow for early detection of respiratory illness and perform an important role in monitoring lung health. There is, in general, a scarcity of data from Africa, and the Global Lung Initiative (GLI) has published global reference equations but models did not include data from African studies. The aim of this study was to investigate lung function in a group of healthy South African females and the applicability of the GLI reference equations. Methodology: Maternal lung function testing was undertaken at 6 to 10 weeks post-partum as
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15

Ólafsdóttir, Inga Sif. "Inflammatory Markers, Respiratory Diseases, Lung Function and Associated Gender Differences." Doctoral thesis, Uppsala universitet, Lungmedicin och allergologi, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-160226.

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Systemic inflammation is associated with impaired lung function. Inflammation is part of asthma and chronic obstructive pulmonary disease (COPD), but the local and systemic inflammatory pattern differs. The overall aim was to evaluate systemic inflammatory markers in obstructive lung diseases and more specifically: To determine if CRP is related to respiratory symptoms, asthma, atopy and bronchial responsiveness (paper I), in a population sample from three countries (paper I and II); to evaluate if CRP is related to COPD, lung function and rate of lung function decline (paper II); to investiga
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16

McClelland, James Robert. "Registration based respiratory motion models for use in lung radiotherapy." Thesis, University College London (University of London), 2008. http://discovery.ucl.ac.uk/1444228/.

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Respiratory motion is a major factor contributing to errors and uncertainties in Radiotherapy (RT) treatment of lung tumours. Knowledge of this motion may improve the planning and delivery of RT treatment for lung cancer patients. This thesis develops and evaluates methods of building patient specific respiratory motion models. These relate the internal motion to respiratory parameters derived from an external surrogate signal that can be measured during data acquisition and treatment delivery. The models offer a number of advantages over current methods of imaging and analysing respiratory mo
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17

Jordan, Simon James. "The pathogenesis of lung injury following cardiothoracic surgery." Thesis, Imperial College London, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.249727.

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18

Messaggi-Sartor, Monique 1984. "Respiratory muscle dysfunction in respiratory and non-respiratory diseases : clinical and therapeutic approaches." Doctoral thesis, Universitat Pompeu Fabra, 2017. http://hdl.handle.net/10803/565809.

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Respiratory muscle dysfunction is a clinical condition that may be present in both respiratory and non-respiratory diseases. This impairment of muscle function can have a negative effect on clinical outcomes, contributing to a further worsening of the patient’s clinical condition. This doctoral thesis has been directed by the ‘Rehabilitation Research Group’ (RERG) in collaboration with the Muscle Wasting and Cachexia in Chronic Respiratory Diseases and Lung Cancer Group (Lung Cancer and Muscle Research Group) of the Institut Hospital del Mar d’Investigacions Mèdiques (IMIM) in Barcelona. Muscl
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19

Backman, Helena. "Lung function and prevalence trends in asthma and COPD : the Obstructive Lung Disease in Northern Sweden Thesis XVI." Doctoral thesis, Umeå universitet, Yrkes- och miljömedicin, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-118026.

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Background Asthma and chronic obstructive pulmonary disease (COPD) are common obstructive airway diseases with a substantial burden in terms of morbidity, mortality and costs. Smoking is the single most important risk factor for COPD, and is associated with incident asthma. It is important to know if the prevalence of asthma and COPD is increasing or decreasing in the population in order to effectively allocate health care resources. The definitions of these diseases have varied over time which makes it difficult to measure changes in prevalence. The preferred method is to estimate the prevale
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20

DeDonder, Keith David. "Lung auscultation as a predictor of lung lesions and bovine respiratory disease outcome in feed yard cattle." Thesis, Manhattan, Kan. : Kansas State University, 2008. http://hdl.handle.net/2097/789.

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21

Wang, Jiali. "Motion Correction Algorithm of Lung Tumors for Respiratory Gated PET Images." FIU Digital Commons, 2009. http://digitalcommons.fiu.edu/etd/96.

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Respiratory gating in lung PET imaging to compensate for respiratory motion artifacts is a current research issue with broad potential impact on quantitation, diagnosis and clinical management of lung tumors. However, PET images collected at discrete bins can be significantly affected by noise as there are lower activity counts in each gated bin unless the total PET acquisition time is prolonged, so that gating methods should be combined with imaging-based motion correction and registration methods. The aim of this study was to develop and validate a fast and practical solution to the problem
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22

Sehlin, Maria. "Resistance breathing with PEP and CPAP : effects on respiratory parameters." Doctoral thesis, Umeå universitet, Anestesiologi och intensivvård, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-94650.

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Background: Positive expiratory pressure (PEP) and continuous positive airway pressure (CPAP) are two forms of resistance breathing used in spontaneously breathing patients. With a threshold resistor or a flow resistor, both PEP and CPAP provide a positive (elevated) pressure level during the expiratory phase. With PEP, inspiratory pressure is negative, i.e. lower than ambient air pressure, as during a normal inspiration, but with CPAP, the inspiratory pressure is positive, i.e. higher than ambient air pressure. Methods: This thesis is based on four separate studies in which four different bre
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23

Johnson, Jo-Anne. "Investigating factors governing cell fate decisions in respiratory epithelium." Thesis, University of Cambridge, 2018. https://www.repository.cam.ac.uk/handle/1810/278966.

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The maintenance of the airway/respiratory epithelium during adult homeostasis and repair and its construction during embryonic development require tightly regulated cell fate decisions. This regulation takes the form of complex transcription factor and signalling cascades, much of which are unknown, particularly in human lung development. Multiciliogenesis describes the process of specification/differentiation of airway epithelial progenitors/stem cells into mature multiciliated cells (MCCs). Here, I have identified 2 novel transcription factors, Fank1 and Jazf1 which form part of the transcri
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24

Kotecha, Sailesh. "The role of cytokines in chronic lung disease of prematurity." Thesis, Imperial College London, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.244032.

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25

O'Dowd, Emma Louise. "Factors influencing the diagnosis and subsequent prognosis in patients with lung cancer." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/42768/.

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Background: The United Kingdom (UK) has poor lung cancer survival rates compared to other countries, and this is partly explained by differences in early mortality. In order to diagnose lung cancer at an earlier stage in the UK there is a pressing need to understand the management process from the recognition of symptoms by people with lung cancer, through the initial interactions with primary care to the referral to secondary care and the choice of the subsequent treatment plan. Objectives: The aim of this thesis is to use mixed methods to identify some of the factors which may affect the dia
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26

Lilburn, D. M. L. "Hyperpolarized noble gas magnetic resonance imaging of the ex vivo rodent lung." Thesis, University of Nottingham, 2015. http://eprints.nottingham.ac.uk/28827/.

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The work described within this thesis was conducted at the University of Nottingham between April 2011 and March 2014. Due to the inter-disciplinary nature of this work it was undertaken by the author in conjunction with the other scientists in the Translational Imaging group at the Sir Peter Mansfield Magnetic Resonance Centre, University of Nottingham and collaborators in both the Pulmonary Biology group, University of Nottingham and the Respiratory Pharmacology group, Imperial College London. Pulmonary hyperpolarized (hp) noble gas magnetic resonance imaging (MRI) has seen increasing develo
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27

Quinlan, Gregory John. "Oxidative damage to extracellular proteins and lipids during acute lung injury." Thesis, Imperial College London, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.281713.

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28

Aggarwal, Anjna. "Mediators and mechanisms of persistent pulmonary neutrophilia in acute lung injury." Thesis, Imperial College London, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.289880.

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29

Tompkins, David H. "Sox2 is a Master Regulator of Differentiation in Respiratory Epithelium." University of Cincinnati / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1307985600.

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30

Veeranki, Sreenivas P., Yan Cao, Shimin Zheng, Megan Quinn, and Liang Wang. "Two Faces in the Lung! Vitamin E and Respiratory and Atopic Diseases." Digital Commons @ East Tennessee State University, 2014. https://dc.etsu.edu/etsu-works/88.

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31

Aydin, Murat. "Aerosolisation and in-vitro deposition of an artificial lung surfactant." Thesis, University of Bath, 1999. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.341146.

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32

Villar, M. Tracey A. "Risk factors for impaired lung function in the elderly." Thesis, University of Southampton, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.339372.

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33

Nelson, Diane L. "Pulmonary Drug Delivery via Reverse Perfluorocarbon Emulsions: A Novel Method for Bacterial Respiratory Infections and Acute Respiratory Failure." Research Showcase @ CMU, 2018. http://repository.cmu.edu/dissertations/1147.

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Inhaled drug delivery is currently the gold standard for treating many respiratory diseases. However, improved treatments are needed for lung diseases like Cystic Fibrosis (CF) and Acute Respiratory Distress Syndrome (ARDS), where mucus or fluid build-up in the lung limits ventilation and, thus, delivery of inhaled drugs. Delivery is most needed in the diseased or damaged regions of the lung, but if an area is not ventilated, inhaled drug will simply not reach it. To overcome this, this research proposes delivering drugs to the lungs within a perfluorocarbon (PFC) liquid. The lungs will be fil
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34

Molter, Anna. "Air pollution exposure and respiratory health in childhood." Thesis, University of Manchester, 2012. https://www.research.manchester.ac.uk/portal/en/theses/air-pollution-exposure-and-respiratory-health-in-childhood(86388151-13d1-499d-be59-89d6d87e036f).html.

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Asthma is the most common chronic disease in children and the effects of air pollution exposure on asthma and respiratory health in children have been a growing concern over recent decades. Although a number of epidemiological studies have been carried out in this field, these have produced conflicting results. The aim of this study was to assess the effects of long term exposure to nitrogen dioxide (NO2) and particulate matter (PM10) on asthma prevalence and lung function in children. To achieve this, a novel exposure model was developed and evaluated, which allowed retrospective exposure ass
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35

Paudyal, Priyamvada. "Respiratory symptoms and lung function in relation to cotton dust and endotoxin exposure in textile workers in Nepal." Thesis, University of Aberdeen, 2011. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=166944.

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Background: Cotton workers are highly exposed to organic dust. Inhalation of cotton based particulate has been associated with various respiratory symptoms and impaired lung function. This study investigates the respiratory health profile of textile mill workers in Nepal in relation to dust and endotoxin exposure. Methods: This study was conducted in four sectors (garment, carpet, weaving and recycling) of the textile industry in Kathmandu, Nepal. A total of 938 individuals completed a health questionnaire and performed spirometry. A subset of 384 workers performed cross-shift spirometry. Pers
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36

Dundas, Isobel. "Simpler methods of assessing respiratory function and their application in infancy." Thesis, University College London (University of London), 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.322574.

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37

Baker, Cathy Sue. "Rationale for surfactant replacement therapy in patients with acute lung injury." Thesis, Imperial College London, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.243281.

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38

Fox, Jane. "Utility of the precision cut lung slice model to investigate airway smooth muscle contraction." Thesis, University of Nottingham, 2011. http://eprints.nottingham.ac.uk/30380/.

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Asthma is characterised by airway remodelling and an increase in airway resistance. A greater understanding of the mechanisms involved in airway inflammation and airway hyper-responsiveness (AHR) may highlight therapeutic opportunities for asthma. This study initially aimed to optimise the preparation of precision cut lung slices (PCLS) in mouse and pig to investigate the influence of calcium (Ca2+) homeostasis on airway smooth muscle (ASM) contraction as a prelude to human studies. The PCLS technique was then applied to a murine model of allergic airway disease to explore the inflammatory pro
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39

Kirk, Megan. "Technology Aiding in Neonatal Lung Developmental Care." Digital Commons @ East Tennessee State University, 2020. https://dc.etsu.edu/honors/594.

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In this paper, old as well as new technological findings to decrease premature infant mortality are reviewed. This paper discusses fetal development throughout pregnancy from conception to full-term status as well as fetal lung development specifically from conception until full-term status. Several ideas to rapidly develop and mature fetal lungs are discussed such as mothers ingesting artificial surfactant supplements, either independently or coupled with antenatal corticosteroids, as well as intra-amniotic instillation prior to 28 weeks gestational. Drawbacks regarding these two are mentione
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40

Latzin, Philipp. "Lung development in health and disease : early-life risk factors and their impact on lung function, inflammation and respiratory symptoms /." [S.l.] : [s.n.], 2009. http://www.ub.unibe.ch/content/bibliotheken_sammlungen/sondersammlungen/dissen_bestellformular/index_ger.html.

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41

Marques, Alda Sofia Pires de Dias. "The use of computer aided lung sound analysis to characterise adventitious lung sounds : a potential outcome measure for respiratory therapy." Thesis, University of Southampton, 2008. https://eprints.soton.ac.uk/65639/.

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A barrier to assessing the effectiveness of respiratory physiotherapy has been insufficient accurate, reliable and sensitive outcome measures. Lung sounds provide useful, specific information for assessing and monitoring respiratory patients. However, standard auscultation techniques are too subjective to allow them to be used as an outcome measure. In this research, Computer Aided Lung Sound Analysis (CALSA) was used to assess whether adventitious lung sounds’ characteristics could be quantified clinically and used as a new objective, non-invasive, bedside clinical outcome measure for physiot
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42

Viret, Muriel. "Effect of hypoxia and reoxygenation on the lower respiratory compartment of the lung /." [S.l.] : [s.n.], 2009. http://opac.nebis.ch/cgi-bin/showAbstract.pl?sys=000288148.

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43

Sefic, Pasic Irmina. "The role of lung ultrasonography in the evaluation of neonatal respiratory distress syndrome." Doctoral thesis, Universitat Autònoma de Barcelona, 2019. http://hdl.handle.net/10803/669429.

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Objetivo de nuestro estudio fue evaluar la capacidad diagnóstica de la ecografía pulmonar en el diagnóstico del Síndrome del Distrés Respiratorio (SDR), así como en el seguimiento de la respuesta al tratamiento. La ecografía pulmonar se comparó con los rayos X como método estándar de diagnóstico y seguimiento de pacientes con SDR. La escala radiográfica de cuatro grados se comparó con perfiles de ultrasonido de tres grados. El segundo objetivo era hacer un cálculo de las dosis recibidas debido a la radiografía de tórax en niños incluidos en el estudio. También se compararon los hallazgos
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44

Pennycook, Alasdair Michael James. "The role of chemokines in lung disease induced by respiratory syncytial virus infection." Thesis, Imperial College London, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.271456.

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45

Drysdale, Simon Bruce. "Diminished lung function, viral infections and chronic respiratory morbidity in prematurely born infants." Thesis, King's College London (University of London), 2014. http://kclpure.kcl.ac.uk/portal/en/theses/diminished-lung-function-viral-infections-and-chronic-respiratory-morbidity-in-prematurely-born-infants(eac3c59e-4db9-4531-823c-237d0cab1e94).html.

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Aims To assess the impact of RSV and other viral lower respiratory tract infections (LRTIs) on chronic respiratory morbidity in prematurely born infants and to investigate whether there were any functional or genetic predisposing factors. Methods One hundred and fifty three prematurely born infants were followed until one year corrected age with approximately half followed until two years of age. Lung function was measured at 36 weeks postmenstrual age (PMA) and one year corrected age. Blood or buccal swabs were taken for single nucleotide polymorphism (SNP) analysis. Following neonatal unit d
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46

Kang, Kingston. "ESTIMATING THE RESPIRATORY LUNG MOTION MODEL USING TENSOR DECOMPOSITION ON DISPLACEMENT VECTOR FIELD." VCU Scholars Compass, 2018. https://scholarscompass.vcu.edu/etd/5254.

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Modern big data often emerge as tensors. Standard statistical methods are inadequate to deal with datasets of large volume, high dimensionality, and complex structure. Therefore, it is important to develop algorithms such as low-rank tensor decomposition for data compression, dimensionality reduction, and approximation. With the advancement in technology, high-dimensional images are becoming ubiquitous in the medical field. In lung radiation therapy, the respiratory motion of the lung introduces variabilities during treatment as the tumor inside the lung is moving, which brings challenges to t
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47

Fulton, Ross Bane. "Regulation of virus-specific T cells in the lung during respiratory virus infections." Diss., University of Iowa, 2010. https://ir.uiowa.edu/etd/803.

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The respiratory system forms a major mucosal interface with the external environment. Consequently, the respiratory tract is constantly exposed to inhaled foreign antigens, commensal microorganisms, and potential pathogens. The respiratory system has evolved a complex regulatory network designed to prevent unnecessary inflammation to harmless antigens and to limit immune-mediated damage to the fragile lung epithelium in response to infection. The lung maintains a default anti-inflammatory state that is coordinated by the respiratory epithelium, alveolar macrophages, dendritic cells, and regula
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48

Wigenstam, Elisabeth. "Pathogenesis and treatment of chemical-induced lung injury." Doctoral thesis, Umeå universitet, Institutionen för folkhälsa och klinisk medicin, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-52738.

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Inhalation of chemical substances can cause irritation to airways and in high doses acute airway injury. When mice are exposed to the alkylating nitrogen mustard analogue melphalan they develop an acute airway inflammation with a rapid influx of neutrophils to the lungs. The acute phase is followed by long-term respiratory complications characterized by bronchitis, lung fibrosis, and airway hyperreactivity.      In this thesis, a mouse model for chemical airway inflammation was established and the effects on the lungs in a time span from 6 hours up to 3 months were investigated in order to stu
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Hipp, Jenny Christine. "EXAMINATION OF SPEECH AND RESPIRATORY PARAMETERS DURING MODERATE AND HIGH INTENSITY WORK." Miami University / OhioLINK, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=miami1133397318.

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50

Rich, Anna. "Validation of the National Lung Cancer Audit database and analysis of the information it contains." Thesis, University of Nottingham, 2012. http://eprints.nottingham.ac.uk/29747/.

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Introduction: Lung cancer is the commonest cause of cancer related death in men and women in England. In 2004 the National Lung Cancer Audit (NLCA) was created, as a national non-mandatory contemporary dataset of clinical features of individuals with lung cancer in part to identify variations in clinical practice and outcomes. The main aims of this dissertation are to determine the validity and representativeness of this dataset and then to investigate what factors influence access to surgery and chemotherapy and subsequent survival. In addition I have taken the opportunity afforded by this la
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