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1

He, Zhong Hai, and Guang Shuai Zhu. "Adjustable Respiratory Mechanical Parameters Lung System for Medical Patient Simulator." Applied Mechanics and Materials 44-47 (December 2010): 4115–19. http://dx.doi.org/10.4028/www.scientific.net/amm.44-47.4115.

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A lung simulator utilizing flow track to simulate spontaneous breathing is presented as an alternative to the existed lung system in the medical patient simulator. The hardware of simulator is similar and updated from Meka’s paper. The existing lung system can be divided into two main types. One is traditional bellows driven mechanical lung system, the other is bellow-less lung simulator driven by carinal pressure that to be controlled. Our lung simulator is upgraded from bellow-less simulator. The research focus on the flow pattern the lung simulator generated which can image the lung mechani
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2

PERRY, STEVEN F. "Functional Morphology of the Lungs of the Nile Crocodile, Crocodylus Niloticus: Non-Respiratory Parameters." Journal of Experimental Biology 134, no. 1 (1988): 99–117. http://dx.doi.org/10.1242/jeb.134.1.99.

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The complex, multicameral lungs of the Nile crocodile are characterized by rows of tubular chambers, which in cranial and ventral lung regions are broad and sac-like. The inner surface of the chambers is enhanced by cubicles (ediculae), the capillary-bearing walls of which are often perforated. Extrabronchial communication among chambers is infrequent. The ediculae end in a network of myoelastic trabeculae, which face the central lumen of the chambers. The trabecular epithelium is similar to that of mammalian bronchi and contains isolated endocrine-like cells basally, whereas the edicular epit
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Sudeep Kale, Mangala Deshpande, Pandurang Thatkar, Sandeep Chaudhari, and Manisha Deshpande. "Study on correlation of inspiratory pulmonary function parameters with anthropometric parameters and analysis of pattern of inspiratory parameters at various age points in Indian Children." International Journal of Research in Pharmaceutical Sciences 12, no. 3 (2021): 2062–68. http://dx.doi.org/10.26452/ijrps.v12i3.4813.

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The prevalence of lung diseases is increasing globally. Mortality, morbidity and respiratory disability are a growing health concern. The pulmonary function test is an accurate tool for detecting airway and lung abnormalities. Early diagnosis of respiratory disease is key to preventing mortality and morbidity. The current study has evaluated the relation of the anthropometric parameters and inspiratory parameters of pulmonary function test and also analyzed its behaviour over the growing age in Indian children. The current study included 2109 school-aged children aged 6 to 15. The height, weig
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Lykhatskyi, P. H., N. V. Ohinska, I. B. Getmanyuk, Z. M. Nebesna, and S. V. Trach Rosolovska. "Morphometric analysis of lungs parameters under conditions of simulated burn injury." Reports of Morphology 29, no. 1 (2023): 34–38. http://dx.doi.org/10.31393/morphology-journal-2023-29(1)-05.

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Thermal burns are one of the most traumatic and physically exhausting injuries. Among the many factors that are decisive for a burn injury, the relationship between the temperature of the damaging agent and the duration of exposure is important. The term of exposure and high temperature determine the depth of the lesion. During burns, hypoxic, hemodynamic and metabolic disorders occur, which lead to changes in the structures and functions of internal organs. There are various ways of developing the respiratory system disorders after a burn injury to the skin: direct thermal damage to the respi
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Al-Robaiy, Samiya, Bettina Weber, Andreas Simm, et al. "The receptor for advanced glycation end-products supports lung tissue biomechanics." American Journal of Physiology-Lung Cellular and Molecular Physiology 305, no. 7 (2013): L491—L500. http://dx.doi.org/10.1152/ajplung.00090.2013.

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The receptor for advanced glycation end-products (RAGE) and its soluble forms are predominantly expressed in lung but its physiological importance in this organ is not yet fully understood. Since RAGE acts as a cell adhesion molecule, we postulated its physiological importance in the respiratory mechanics. Respiratory function in a buffer-perfused isolated lung system and biochemical parameters of the lung were studied in young, adult, and old RAGE knockout (RAGE-KO) mice and wild-type (WT) mice. Lungs from RAGE-KO mice showed a significant increase in the dynamic lung compliance and a decreas
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Svitlytska, O., O. Fedorova, S. Ustinova, T. Kiknadze, and O. Kucherenko. "EVALUATION OF EXTERNAL RESPIRATORY PARAMETERS USING BODYPLETHISMOGRAPHY IN PATIENTS WITH OBESITY." Znanstvena misel journal, no. 86 (January 27, 2024): 25–28. https://doi.org/10.5281/zenodo.10575790.

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<strong>Objective.</strong> To evaluate the parameters of bodyplethysmography in obese patients. <strong>Materials and methods.</strong> 52 patients were examined, who were divided into groups: Group I - practically healthy persons - 10, Group II - patients with excess body weight - 11, Group III - 31 obese patients. There were assessed: Body mass index (BMI) and lung function by bodyplethysmography. <strong>Results.</strong> In obese patients, there was an increase in the effective specific resistance of the airways (sReff), the total specific resistance of the airways (Rtot), a decrease in t
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7

Jayasekera, Shehan, Edward Hensel, and Risa Robinson. "Feasibility of Using the Hexoskin Smart Garment for Natural Environment Observation of Respiration Topography." International Journal of Environmental Research and Public Health 18, no. 13 (2021): 7012. http://dx.doi.org/10.3390/ijerph18137012.

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Background: Limited research has been done to measure ambulatory respiratory behavior, in particular those associated with tobacco use, in the natural environment due to a lack of monitoring techniques. Respiratory topography parameters provide useful information for modeling particle deposition in the lung and assessing exposure risk and health effects associated with tobacco use. Commercially available Wearable Respiratory Monitors (WRM), such as the Hexoskin Smart Garment, have embedded sensors that measure chest motion and may be adapted for measuring ambulatory lung volume. Methods: Self-
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8

Kulkarni, Apoorva S., and Sheela N. "Methods to Evaluate Airway Resistance and Lung Compliance During Mechanical Ventilation: A Comparative Study." International Journal of Innovative Science and Research Technology 5, no. 7 (2020): 947–51. http://dx.doi.org/10.38124/ijisrt20jul666.

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Mechanical ventilation is a lifesaving activity that is used in critical care management. In such case, monitoring of airway resistance(Raw) and lung compliance(CL) play a major role for diagnosing the lung condition, setting the ventilator parameters, can act as a decision parameter for weaning the patient from the ventilator. Several methods have been described for estimating these respiratory parameters. In this work, a study is conducted to compare two different methods used to calculate airway resistance and lung compliance during mechanical ventilation. Michigan Adult/Infant lung simulat
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9

Lehtimäki, Lauri, Tuomas Karvonen, and Marieann Högman. "Clinical Values of Nitric Oxide Parameters from the Respiratory System." Current Medicinal Chemistry 27, no. 42 (2020): 7189–99. http://dx.doi.org/10.2174/0929867327666200603141847.

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Background: Fractional exhaled nitric oxide (FENO) concentration reliably reflects central airway inflammation, but it is not sensitive to changes in the NO dynamics in the lung periphery. By measuring FENO at several different flow rates one can estimate alveolar NO concentration (CANO), bronchial NO flux (JawNO), bronchial wall NO concentration (CawNO) and the bronchial diffusivity of NO (DawNO). Objective: We aimed to describe the current knowledge and clinical relevance of NO parameters in different pulmonary diseases. Methods: We conducted a systematic literature search to identify public
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10

Chernyak, A. V., M. Kh Mustafina, Zh K. Naumenko, E. N. Kalmanova, and K. A. Zykov. "Dynamics of functional changes in the respiratory system after COVID-19-associated lung injury at one year after hospital discharge." PULMONOLOGIYA 33, no. 5 (2023): 611–21. http://dx.doi.org/10.18093/0869-0189-2023-33-5-611-621.

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Morphological examination reveals microcirculation disorders in combination with small areas of lung damage in the long term after COVID-19. Therefore, the function of the respiratory system should be assessed after COVID-19. Aim of this study was to evaluate the dynamics of respiratory dysfunction in patients with COVID-19-associated lung injury using a complex examination of lung function (spirometry, body plethysmography, and lung diffusion testing) one year after hospital discharge. Methods. 60 patients (38 men/22 women, aged 39 to 80 years) with a diagnosis of “COVID-19-associated interst
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Horalskyi, L., N. Hlukhova, and I. Sokulskyi. "Morphological traits of rabbit lung." Scientific Horizons 93, no. 8 (2020): 180–88. http://dx.doi.org/10.33249/2663-2144-2020-93-8-180-188.

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In the article, following the results of complex methods (anatomic, histologic, organometric, histometric and statistical) researches are shown the features of morphological structure and morphometric parameters of the lungs of mature rabbits. It was found out, that macro- and microscopic architecture of rabbit lungs has similar histoarchitectonics, inherent in other species of farm animals of the class "mammals" and the characteristic features of morphological structures. Lungs in clinically healthy rabbits structurally reflect the shape of thoracic cavity and gradually expand ventrally. Subs
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12

Povodator, Arkadi, Vladimir Tsepelev, and Natali Kulikova. "Respiratory Parameters-Based Approach to Assessing Dust Loading." Key Engineering Materials 660 (August 2015): 305–8. http://dx.doi.org/10.4028/www.scientific.net/kem.660.305.

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The idea of assessing the respiratory organs’ protection means has been considered, that takes into account the dust penetration coefficient and dynamics of the worker’s cardio respiratory parameters under working conditions. The individual samplers’ speed is proposed to be controlled by means of the lung ventilation while dust loading inside and outside the individual protection means is to be determined. This enables assessing them by a conventional performance factor taking into account cardio respiratory parameters as well.
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13

Trivedi, Deepshikha, and Arijit Kumar Das. "Effect of Intercostal Stretch and Breathing Control Exercise on Lung Function among Healthy Young Females." International Journal of Health Sciences and Research 12, no. 2 (2022): 64–70. http://dx.doi.org/10.52403/ijhsr.20220208.

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Introduction: Intercostal (IC) muscles help in upward and outward movement of the ribs which results in increase in antero-posterior diameter of the thoracic cavity. The use of manual stretching procedure is prevalent in respiratory physiotherapy to improve pulmonary functions. Objective: To determine the effect of Intercostal (IC) stretch and breathing control in improving the lung function parameters (Forced Expiratory Volume) in the first second (FEV1), Forced Vital Capacity (FVC) and FEV1/FVC % and respiratory rate among healthy young females. Methodology: Thirty healthy female subjects, a
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14

Bates, J. H., K. A. Brown, and T. Kochi. "Respiratory mechanics in the normal dog determined by expiratory flow interruption." Journal of Applied Physiology 67, no. 6 (1989): 2276–85. http://dx.doi.org/10.1152/jappl.1989.67.6.2276.

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We recently proposed an eight-parameter model of the respiratory system to account for its mechanical behavior when flow is interrupted during passive expiration. The model consists of two four-parameter submodels representing the lungs and the chest wall, respectively. The lung submodel consists of an airways resistance together with elements embodying the viscoelastic properties of the lung tissues. The chest wall submodel has similar structure. We estimated the parameters of the model from data obtained in four normal, anesthetized, paralyzed, tracheostomized mongrel dogs. This model explai
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15

Bates, Jason H. T., Charles G. Irvin, Ramon Farré, and Zoltán Hantos. "Oscillation Mechanics of the Respiratory System." Comprehensive Physiology 1, no. 3 (2011): 1233–72. https://doi.org/10.1002/j.2040-4603.2011.tb00366.x.

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AbstractThe mechanical impedance of the respiratory system defines the pressure profile required to drive a unit of oscillatory flow into the lungs. Impedance is a function of oscillation frequency, and is measured using the forced oscillation technique. Digital signal processing methods, most notably the Fourier transform, are used to calculate impedance from measured oscillatory pressures and flows. Impedance is a complex function of frequency, having both real and imaginary parts that vary with frequency in ways that can be used empirically to distinguish normal lung function from a variety
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16

Min, Ji Young, Sung Woo Hyung, Joon Pyo Jeon, Mee Young Chung, Chang Jae Kim, and Yoon Hee Kim. "A stepwise lung recruitment maneuver using I-gel can improve respiratory parameters: A prospective observational study." Medicine 103, no. 26 (2024): e38718. http://dx.doi.org/10.1097/md.0000000000038718.

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I-gel has been used in various clinical situations. The study investigated alterations in respiratory parameters following a stepwise lung recruitment maneuver (LRM) using the i-gel. The research involved 60 patients classified as American Society of Anesthesiologists class I-II, aged 30 to 75 years, undergoing elective urologic surgery. Various respiratory parameters, including lung compliance, airway resistance, leak volume, airway pressure, and oxygen reserve index, were recorded at different time points: before LRM, immediately after LRM, and at 5, 15, and 30 minutes after LRM, as well as
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17

Kiryukhina, L. D., V. V. Sysoeva, E. V. Kokorina, and P. K. Yablonsky. "THE CORRELATION BETWEEN IMPULSE OSCILLOMETRY PARAMETERS AND RESPIRATORY MUSCLE STRENGTH IN PULMONARY TB PATIENTS." Вестник ЦНИИТ 9, no. 2 (2025): 44–57. https://doi.org/10.57014/2587-6678-2025-9-2-44-57.

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Little information is available about respiratory muscle (RM) function in pulmonary TB patients. Aim: to study the correlation between the parameters of impulse oscillometry (IOS) and RM strength in pulmonary TB patients. TMaterials and methods. The study enrolled 214 patients with confirmed pulmonary TB. We performed measurements of maximal occlusive inspiratory (PImax) and expiratory (PEmax) mouth pressures, IOS test, spirometry, body plethysmography, and lung diffusion testing.The Spearman correlation was established. Results. PImax witnessed moderate correlation, mostly with lung elastic p
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18

Yin, Yize, Chaohui Mu, Jiahui Wang, et al. "CXCL17 Attenuates Diesel Exhaust Emissions Exposure-Induced Lung Damage by Regulating Macrophage Function." Toxics 11, no. 8 (2023): 646. http://dx.doi.org/10.3390/toxics11080646.

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Exposure to diesel exhaust emissions (DEE) is strongly linked to innate immune injury and lung injury, but the role of macrophage chemoattractant CXCL17 in the lung damage caused by DEE exposure remains unclear. In this study, whole-body plethysmography (WBP), inflammatory cell differential count, and histopathological analysis were performed to assess respiratory parameters, airway inflammation, and airway injury in C57BL/6 male mice exposed to DEE for 3 months. qRT-PCR, IHC (immunohistochemistry), and ELISA were performed to measure the CXCL17 expression in airway epithelium or BALF (broncho
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19

Torregiani, Chiara, Chiara Veneroni, Paola Confalonieri, et al. "Monitoring respiratory mechanics by oscillometry in COVID-19 patients receiving non-invasive respiratory support." PLOS ONE 17, no. 3 (2022): e0265202. http://dx.doi.org/10.1371/journal.pone.0265202.

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Background Non-invasive ventilation (NIV) has been increasingly used in COVID-19 patients. The limited physiological monitoring and the unavailability of respiratory mechanic measures, usually obtainable during invasive ventilation, is a limitation of NIV for ARDS and COVID-19 patients management. Objectives This pilot study was aimed to evaluate the feasibility of non-invasively monitoring respiratory mechanics by oscillometry in COVID-19 patients with moderate-severe acute respiratory distress syndrome (ARDS) receiving NIV. Method 15 COVID-19 patients affected by moderate-severe ARDS at the
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Subramanian, N. Siva, B. Mahalakshmi, Darji Deep Chiragkumar, Chirag Rohitbhai Sathwara, Shylaja Kailash Attur, and Kailash Attur. "Effectiveness of Balloon Blowing on Respiratory Parameters among Children with Lower Respiratory Tract Infection: A Quasi-Experimental Study." Journal of Pharmacy and Bioallied Sciences 17, Suppl 2 (2025): S1239—S1241. https://doi.org/10.4103/jpbs.jpbs_1978_24.

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ABSTRACT Introduction: Lower respiratory tract infections (LRTIs) are common cause of morbidity among children. Noninvasive interventions like balloon-blowing exercises have been explored for their potential to improve respiratory function. Materials and Methods: A quasi-experimental, non-equivalent control group design was used for children with LRTIs. The experimental group (n = 30) practiced balloon blowing exercises for 10 min daily over a period of two weeks, while control group (n = 30) received standard care. Respiratory parameters, including respiratory rate, oxygen saturation, and lun
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HORALSKYI, LEONID, NATALIIA HLUKHOVA, IHOR SOKULSKYI, and NATALIIA KOLESNIK. "MORPHOLOGICAL FEATURES AND MORPHOMETRIC PARAMETERS OF THE LUNGS OF SEXUALLY MATURE HORSES (EQUUS FERUS CABALLUS L., 1758)." Ukrainian journal of veterinary sciences 13, no. 1 (2022): 25–33. http://dx.doi.org/10.31548/ujvs.13(1).2022.25-33.

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The lungs, which form part of the respiratory apparatus, provide gas exchange between the environment and the tissues of the human and animal body. Therefore, lung diseases are one of the most pressing issues for modern humane and veterinary medicine. This problem is caused by the progressive growth of diseases in mammals such as bronchial asthma, bronchitis, bronchopneumonia, pneumonia, coronavirus infections, etc. Therefore, to effectively solve this issue in terms of prevention, effective treatment, and prompt differential diagnosis of respiratory diseases, an essential area in morphology i
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Dechman, G., J. Sato, and JH Bates. "Effect of pleural effusion on respiratory mechanics, and the influence of deep inflation, in dogs." European Respiratory Journal 6, no. 2 (1993): 219–24. http://dx.doi.org/10.1183/09031936.93.06020219.

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We wished to study how pleural effusion affects dynamic mechanics of the lung and the chest wall. We also determined if these changes could be reversed by deep lung inflations. Pleural effusion was produced by saline infusion into the pleural space. During the infusion and over the following 2 hours, dynamic elastance and resistance of the lungs, the chest wall and the whole respiratory system were recorded. Dynamic elastance and resistance of the lung increased significantly during fluid loading and were partially, and only transiently, reversed by deep inflations. Dynamic elastance and resis
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Vlasov, A. P., V. A. Trofimov, T. I. Vlasova, et al. "Pulmonary distress syndrome in urgent surgery: A concept, pathogenesis, and fundamentals of treatment." Pirogov Russian Journal of Surgery, no. 2 (February 7, 2025): 77. https://doi.org/10.17116/hirurgia202502177.

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Objective. To study several non-respiratory lung functions in conjunction with the respiratory component in acute abdominal diseases with different natures of the inflammatory process; to identify the key mechanisms of organ damage; and, based on the data, establish a new syndrome in urgent surgery—pulmonary distress syndrome—and evaluate the effectiveness of Remaxol in its treatment. Material and methods. Chronic experiments have been done on dogs. Under anesthesia, progressive acute peritonitis was simulated in the first group (24) (the first subgroup (12) received infusion therapy, the seco
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Chacón-Lozsán, Francisco, and Peter Tamasi. "Comparing lung mechanics of patients with COVID related respiratory distress syndrome versus non-COVID acute respiratory distress syndrome: a retrospective observational study." Journal of Mechanical Ventilation 3, no. 4 (2022): 151–57. https://doi.org/10.53097/JMV.10062.

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<strong>Abstract</strong> <strong>Background</strong> Most patients admitted to the intensive care unit with coronavirus disease (COVID-19) develop severe respiratory failure. Understanding lung mechanics helps to guide protective mechanical ventilation, improve oxygenation, and reduce the ventilator induce lung injury. This study aims to describe lung mechanics characteristics of patients with COVID -19 related acute respiratory distress syndrome (CARDS) and to compare them with non-COVID-19 associated ARDS.&nbsp; <strong>Methods</strong> We performed a retrospective observational study of lu
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Antonis, Adriaan F. G., Remco S. Schrijver, Franz Daus, et al. "Vaccine-Induced Immunopathology during Bovine Respiratory Syncytial Virus Infection: Exploring the Parameters of Pathogenesis." Journal of Virology 77, no. 22 (2003): 12067–73. http://dx.doi.org/10.1128/jvi.77.22.12067-12073.2003.

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ABSTRACT The bovine and human respiratory syncytial viruses cause severe lower respiratory tract infections. Effective vaccines against the respiratory syncytial viruses have been lacking since vaccine failures in the 1960s and 1970s. In this report, we describe a bovine respiratory syncytial virus (bRSV) challenge model in which both classical bRSV respiratory infection and vaccine-enhanced immune pathology were reproduced. The classical, formalin-inactivated (FI) bRSV vaccine that has been associated with vaccine failure was efficient in inducing high antibody titers and reducing viral loads
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Canham, Lydia, Carolin Steinack, René Hage, et al. "Coronavirus infection and chronic lung allograft dysfunction: a retrospective cohort study." Swiss Medical Weekly 155, no. 7 (2025): 3568. https://doi.org/10.57187/s.3568.

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INTRODUCTION: Long-term survival in lung transplant recipients is limited by chronic lung allograft dysfunction, which can be triggered by respiratory tract infections. STUDY AIMS: We investigated the incidence of chronic lung allograft dysfunction in a cohort of lung transplant recipients over 10 years, focusing on its association with human coronavirus (HCoV) respiratory tract infections and all-cause mortality. METHODS: This 10-year retrospective cohort included 259 lung transplant recipients between 2010 and 2020. Nasopharyngeal swab samples were analysed during regular outpatient visits a
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Gatera, Vesara Ardhe, Rizky Abdulah, Ida Musfiroh, Raden Tina Dewi Judistiani, and Budi Setiabudiawan. "Updates on the Status of Vitamin D as a Risk Factor for Respiratory Distress Syndrome." Advances in Pharmacological Sciences 2018 (September 30, 2018): 1–6. http://dx.doi.org/10.1155/2018/8494816.

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To update the guidelines regarding vitamin D status in respiratory distress syndrome, we reviewed recent human and animal studies on the benefits of vitamin D in respiratory distress. We searched PubMed and ProQuest for studies on the use of vitamin D from 2009 to 2017. The common parameters in these studies included the use of lung tissue, phospholipids, blood, and plasma to assess the effects of vitamin D on respiratory syndrome. The metabolized form of vitamin D used in these studies was 1,25(OH)2D3 in animal studies and 25(OH)D in human studies. Vitamin D supplementation decreases the risk
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Brocklehurst, Robert J., Emma R. Schachner, Jonathan R. Codd, and William I. Sellers. "Respiratory evolution in archosaurs." Philosophical Transactions of the Royal Society B: Biological Sciences 375, no. 1793 (2020): 20190140. http://dx.doi.org/10.1098/rstb.2019.0140.

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The Archosauria are a highly successful group of vertebrates, and their evolution is marked by the appearance of diverse respiratory and metabolic strategies. This review examines respiratory function in living and fossil archosaurs, focusing on the anatomy and biomechanics of the respiratory system, and their physiological consequences. The first archosaurs shared a heterogeneously partitioned parabronchial lung with unidirectional air flow; from this common ancestral lung morphology, we trace the diverging respiratory designs of bird- and crocodilian-line archosaurs. We review the latest evi
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Revinskaya, I. I. "Mathematical Model for Estimation of Volume Respiratory Parameters." Doklady BGUIR 21, no. 1 (2023): 19–25. http://dx.doi.org/10.35596/1729-7648-2023-21-1-19-25.

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A mathematical model of the biomechanics of human respiration has been developed. To verify the proposed mathematical model, it is suggested to use a photo-optical method for recording the biomechanics of the chest and abdomen together with spirometry. Pilot studies were carried out among 10 men aged 20–22. The body mass index of the subjects ranged from 19.3 to 21.5 kg/m², height – from 169 to 182 cm, weight – from 55 to 70 kg. Correlation-regression analysis of the results showed a strong relationship between biomechanical movements of the chest and abdominal walls and changes in the diamete
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Stamenovic, D., K. R. Lutchen, and G. M. Barnas. "Alternative model of respiratory tissue viscoplasticity." Journal of Applied Physiology 75, no. 3 (1993): 1062–69. http://dx.doi.org/10.1152/jappl.1993.75.3.1062.

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Respiratory tissue impedance exhibits both tidal volume and frequency dependences in the ranges of normal breathing. Hildebrandt argued that these indicate tissue viscoplasticity and offered a model in support of his argument consisting of viscoelastic and plastoelastic compartments, both mechanically in parallel (J. Appl. Physiol. 28: 365–372, 1970). Although the model appears to be qualitatively consistent with oscillatory behavior of a wide variety of respiratory tissues, it yields only moderately good quantitative correspondences despite a relatively large number of parameters, eight. One
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Brygin, P. A., S. V. Zhuravel, D. A. Troitskiy, and I. I. Utkina. "Predictors of extracorporeal membrane oxygenation efficacy in patients with acute respiratory failure." Transplantologiya. The Russian Journal of Transplantation 12, no. 3 (2020): 220–30. http://dx.doi.org/10.23873/2074-0506-2020-12-3-220-230.

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The purpose of this article is to describe the problem of predicting the lung function recovery in patients with extracorporeal membrane oxygenation for acute respiratory distress syndrome. Data from CESAR and EOLIA clinical trials on the efficacy of extracorporeal membrane oxygenation in patients with acute respiratory distress syndrome have been reviewed and some controversial results discussed. The prognostic PRESERVE and RESP scores developed as prognostic tools on the basis of the results of these studies, are presented, the limitations of their applicability in various forms of acute res
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Mostovoi, A. V., S. S. Mezhinsky, A. L. Karpova, D. Yu Ovsyannikov, V. V. Gorev, and A. N. Nikolishin. "MECHANICAL VENTILATION WITH A TARGET TIDAL VOLUME IN NEWBORNS AND CHILDREN WITH VARIOUS LUNG DISEASES AT EARLY AGES: PROTOCOL FOR PREPARATION OF THE RESPIRATORY EQUIPMENT AND VENTILATIVE CONTROL." Pediatria. Journal named after G.N. Speransky 101, no. 1 (2022): 148–54. http://dx.doi.org/10.24110/0031-403x-2022-101-1-148-154.

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One of the leading trends in modern medicine is the principle of prevention, which consists in preventing the formation of diseases and complications of therapy. The main damaging factor during respiratory support in patients with inhomogeneous lung tissue injury is tidal volume (TV). With traditional pressure controlled mechanical ventilation (PCMV), controlling the TV delivered to the child is difficult due to the variable mechanical properties of the lung tissue. PCMV algorithms with targeted TV, used in neonatology and in young children, make it possible to adjust the parameters of endotra
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Seybold, Benjamin, Anna M. Deutsch, Barbara Luise Deutsch, et al. "Differential Effects of Intra-Abdominal Hypertension and ARDS on Respiratory Mechanics in a Porcine Model." Medicina 60, no. 6 (2024): 843. http://dx.doi.org/10.3390/medicina60060843.

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Background and Objectives: Intra-abdominal hypertension (IAH) and acute respiratory distress syndrome (ARDS) are common concerns in intensive care unit patients with acute respiratory failure (ARF). Although both conditions lead to impairment of global respiratory parameters, their underlying mechanisms differ substantially. Therefore, a separate assessment of the different respiratory compartments should reveal differences in respiratory mechanics. Materials and Methods: We prospectively investigated alterations in lung and chest wall mechanics in 18 mechanically ventilated pigs exposed to va
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Lee, Jung Ae, Chul Yong Kim, Dae Sik Yang, et al. "Four-Dimensional Computed Tomography Based Respiratory-Gated Radiotherapy with Respiratory Guidance System: Analysis of Respiratory Signals and Dosimetric Comparison." BioMed Research International 2014 (2014): 1–10. http://dx.doi.org/10.1155/2014/306021.

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Purpose. To investigate the effectiveness of respiratory guidance system in 4-dimensional computed tomography (4DCT) based respiratory-gated radiation therapy (RGRT) by comparing respiratory signals and dosimetric analysis of treatment plans.Methods. The respiratory amplitude and period of the free, the audio device-guided, and the complex system-guided breathing were evaluated in eleven patients with lung or liver cancers. The dosimetric parameters were assessed by comparing free breathing CT plan and 4DCT-based 30–70% maximal intensity projection (MIP) plan.Results. The use of complex system
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35

Lindsey, Ashley S., Lydia M. Sullivan, Nicole A. Housley, et al. "Analysis of pulmonary vascular injury and repair during Pseudomonas aeruginosa infection-induced pneumonia and acute respiratory distress syndrome." Pulmonary Circulation 9, no. 1 (2019): 204589401982694. http://dx.doi.org/10.1177/2045894019826941.

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Herein we describe lung vascular injury and repair using a rodent model of Pseudomonas aeruginosa pneumonia-induced acute respiratory distress syndrome (ARDS) during: 1) the exudative phase (48-hour survivors) and 2) the reparative/fibro-proliferative phase (1-week survivors). Pneumonia was induced by intratracheal instillation of P. aeruginosa strain PA103, and lung morphology and pulmonary vascular function were determined subsequently. Pulmonary vascular function was assessed in mechanically ventilated animals in vivo (air dead space, PaO2, and lung mechanics) and lung permeability was dete
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36

Postolache, Paraschiva, Mihaela Moscalu, Alina Croitoru, and Gabriela Jimborean. "Functional and Nonfunctional Parameters in Patients with Occupational Lung Diseases." Materiale Plastice 54, no. 3 (2017): 535–38. http://dx.doi.org/10.37358/mp.17.3.4889.

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Patients with occupational lung diseases (OLD) may present respiratory functional impairment, exertional dyspnea and decreased exercise tolerance. These factors lead to reduced daily physical activity, social isolation, decreased quality of life (QoL) and depression. Assessment of respiratory functional status in patients with OLD in correlation with the presence of anxiety and depression and the quality of life in patients with OLD, as extrapulmonary comorbidities. In patients with diagnosed OLD, the following parameters were evaluated: pulmonary function tests (FEV1, FVC), anxiety and depres
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Bayat, Sam, Jim Wild, and Tilo Winkler. "Lung functional imaging." Breathe 19, no. 3 (2023): 220272. http://dx.doi.org/10.1183/20734735.0272-2022.

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Pulmonary functional imaging modalities such as computed tomography, magnetic resonance imaging and nuclear imaging can quantitatively assess regional lung functional parameters and their distributions. These include ventilation, perfusion, gas exchange at the microvascular level and biomechanical properties, among other variables. This review describes the rationale, strengths and limitations of the various imaging modalities employed for lung functional imaging. It also aims to explain some of the most commonly measured parameters of regional lung function. A brief review of evidence on the
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Chacón-Lozsán, Francisco, and Péter Tamási. "Comparing lung mechanics of patients with COVID related respiratory distress syndrome versus non-COVID acute respiratory distress syndrome: a retrospective observational study." Journal of Mechanical Ventilation 3, no. 4 (2022): 151–57. http://dx.doi.org/10.53097/jmv.10062.

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Background Most patients admitted to the intensive care unit with coronavirus disease (COVID-19) develop severe respiratory failure. Understanding lung mechanics helps to guide protective mechanical ventilation, improve oxygenation, and reduce the ventilator induce lung injury. This study aims to describe lung mechanics characteristics of patients with COVID -19 related acute respiratory distress syndrome (CARDS) and to compare them with non-COVID-19 associated ARDS. Methods We performed a retrospective observational study of lung mechanics: plateau pressure (Pplat), Driving pressure (DP), Mec
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Gauchan, Eva, Ganesh BK, and Deepak Prasad Koirala. "Variation in spirometry parameters in children with and without recurrent respiratory problems." Journal of Kathmandu Medical College 9, no. 3 (2020): 130–36. http://dx.doi.org/10.3126/jkmc.v9i3.36413.

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Background: Children having recurrent episodes of respiratory symptoms account for a major source of hospitalization. These children have increased morbidities and if not identified in time can have impaired lung function as adults. &#x0D; Objectives: The aim of our study was to compare the spirometry parameters and bronchodilator reversibility in children with and without recurrent respiratory problems.&#x0D; Methodology: This was a prospective observational study conducted in the Pediatric department of Manipal Teaching Hospital comparing 35 children with recurrent respiratory problems and 3
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Bakhtiar, Arief, and Wirya Sastra Amran. "Faal Paru Statis." Jurnal Respirasi 2, no. 3 (2019): 91. http://dx.doi.org/10.20473/jr.v2-i.3.2016.91-98.

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Respiration or breathing is the body’s attempt to meet the needs of O2 in the metabolic process and emit CO2 as a result of intermediary metabolism by lung and respiratory organs together so that the resulting cardiovascular oxygen rich blood. Respiration has three phases: ventilation, diffusion, perfusion. The situation is said to somebody normal lung function if the work process of ventilation, diffusion, perfusion, and the relationship between ventilation to perfusion of the person is in a relaxed state resulted in the partial pressure of arterial blood gas (PaO2 and PaCO2) were normal. Exa
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41

Mezhinsky, S. S., A. V. Mostovoy, A. L. Karpova, V. V. Gorev, D. Yu Ovsyannikov, and A. L. Zaplatnikov. "Respiratory support in children with severe bronchopulmonary dysplasia. A bibliographical review." Pediatria. Journal named after G.N. Speransky 103, no. 1 (2024): 146–52. http://dx.doi.org/10.24110/0031-403x-2024-103-1-146-152.

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Bronchopulmonary dysplasia (BPD) is a chronic lung disease of multifactorial etiology characterized by the formation of respiratory failure and regressing as the child grows. With a severe form of BPD, adequate and safe respiratory support is required for a long time. The mechanical properties of the lungs in these patients differ significantly from those in acute respiratory pathology, which should be taken into account when setting the parameters of the ventilator. Important task is to determine the optimal moment for the transition to a strategy of respiratory support for damaged lungs, whi
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Okrzymowska, Paulina, Monika Kurzaj, Wojciech Seidel, and Krystyna Rożek-Piechura. "Eight Weeks of Inspiratory Muscle Training Improves Pulmonary Function in Disabled Swimmers—A Randomized Trial." International Journal of Environmental Research and Public Health 16, no. 10 (2019): 1747. http://dx.doi.org/10.3390/ijerph16101747.

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Background: According to the literature, inspiratory muscle fatigue may increase after swimming training (ST). This study aimed to examine the efficacy of 8-week inspiratory muscular training (IMT) in disabled swimmers, combined with standard sports training, on selected parameters of lung ventilation and the function of respiratory muscles. Methods: A total of 16 disabled swimming division athletes from Wroclaw’s ‘Start’ Regional Sports Association qualified for the study. The subjects were randomly divided into two groups (ST and IMT). Both groups participated in swimming training for 8 week
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N.K., Abdrakhman, and Balabekova M.K. "EXTERNAL RESPIRATORY DISTURBANCES AFTER A PULMONARY PATHOLOGY." ИННОВАЦИОННЫЕ НАУЧНЫЕ ИССЛЕДОВАНИЯ 2023. 1-2(25) (February 5, 2023): 4–14. https://doi.org/10.5281/zenodo.7607832.

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The study was conducted among students who recovered from Covid-19 in the period from April 2020 to February 2022 in mild and moderate severity. Informed consent was obtained from all participants for voluntary participation in the study. The article presents the results of surveyed students who recovered from COVID-19 (41 people) in the summer period of 2020. Among the studied parameters in pre- and post-exercise tests, the most significant studies were noted for such parameters as: VC, FVC, FEV1, FEV1/VC, PEF, FEF25, FEF50, FEF75, MEF25-75. The analysis of the conducted studies showed that,
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Simonte, Rachele, Gianmaria Cammarota, Luigi Vetrugno, Edoardo De Robertis, Federico Longhini, and Savino Spadaro. "Advanced Respiratory Monitoring during Extracorporeal Membrane Oxygenation." Journal of Clinical Medicine 13, no. 9 (2024): 2541. http://dx.doi.org/10.3390/jcm13092541.

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Advanced respiratory monitoring encompasses a diverse range of mini- or noninvasive tools used to evaluate various aspects of respiratory function in patients experiencing acute respiratory failure, including those requiring extracorporeal membrane oxygenation (ECMO) support. Among these techniques, key modalities include esophageal pressure measurement (including derived pressures), lung and respiratory muscle ultrasounds, electrical impedance tomography, the monitoring of diaphragm electrical activity, and assessment of flow index. These tools play a critical role in assessing essential para
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Otelea, Marina Ruxandra, Oana Cristina Arghir, Corina Zugravu, Eugenia Naghi, Sabina Antoniu, and Agripina Rascu. "Lung Function and Quality of Life in Workers with Chemical and Dust Exposure." Revista de Chimie 69, no. 2 (2018): 346–49. http://dx.doi.org/10.37358/rc.18.2.6104.

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Regarding the widely distribution of respiratory exposure hazards in occupational settings, workers have an increased risk for chronic lung diseases. For assessing the quality of life and lung function in workers exposed to chemicals and dust, St George�s Respiratory Questionnaire (SGRQ) and spirometry were performed among 40 patients, admitted in Occupational Clinic Department of Colentina Hospital, Bucharest, Romania, during February, 2017. SGRQ showed different predictors for patients according to their occupational exposure and total symptoms score correlated better with decreased spiromet
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Nileshbhai, Solanki, Nita Gosai, Leena Ramteke, and Vasantray Bhimani. "A comparative study of two lung ventilation versus one lung ventilation for video-assisted thoracoscopic esophagectomy in semiprone position (airway management for thoracoscopic esophagectomy)." Serbian Journal of Anesthesia and Intensive Therapy 46, no. 3-4 (2024): 53–59. http://dx.doi.org/10.5937/sjait2404053s.

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Thoracoscopic esophagectomy is a complex procedure used for the treatment of esophageal cancer in which One Lung Ventilation (OLV) anesthesia is often used with several disadvantages associated mainly with respiratory system. But nowadays, the Two Lung Ventilation (TLV) approach has become popular due to reduction in induction time of anesthesia and better perioperative outcomes. The aim was to compare intraoperative respiratory functions and perioperative surgical parameters between One Lung Ventilation and Two Lung Ventilation anesthesia. Methods: In this randomised, prospective, double-blin
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47

Ghaidaa A. Khalid, Mohammed I. Abdulmawjod, and Ali Al-Bayaty. "A Comprehensive Analysis of Respiratory Patterns and Physiological Parameters in Asthma, Bronchitis, and Croup." Electrical Engineering Technical Journal 1, no. 1 (2024): 35–49. http://dx.doi.org/10.51173/eetj.v1i1.3.

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Asthma is the most common misdiagnosed lung disease, especially for children aged 6 -15 years old. There was limited research done to isolate asthmatic symptoms from other common lung conditions, such as bronchitis and croup, as they often share very similar symptoms. This can cause the symptoms to worsen over time if the child is wrongly diagnosed. This study isolates asthma symptoms in children from other similar lung diseases and identifies a specific unique breathing pattern that isolates each other's lung disease. Within this study, asthma will be compared with bronchitis and croup. A ser
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48

Yogesh, Kacha, Nayak Yagnesh, Vegad Anup, Varu Maulik, Mehta Hemant, and J. Shah C. "EFFECTS OF WOOD DUST ON RESPIRATORY FUNCTIONS IN SAW MILL WORKERS." International Journal of Basic & Applied Physiology 3, no. 1 (2014): 99–105. https://doi.org/10.5281/zenodo.4476059.

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Background &amp; Objectives: Occupational pulmonary diseases are more widespread and more disabling than any other group of occupational disease. The lung with its extensive surface area, high blood flow and thin alveolar epithelium is an important site of contact with substance in environment. The inhalation of dust over periods of time leads to proliferation and fibrotic changes in lungs. The workers working in industries suffer from various types of air way diseases like pneumoconiosis, farmer&rsquo;s lung, chronic bronchitis, pulmonary fibrosis and asthma. So the present study was undertak
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Zayneev, M. M., N. I. Ziyatdinova, and T. L. Zefirov. "Peculiarities of the functional state of external respiration of primary school children during adaptation to different efforts." Kazan medical journal 93, no. 1 (2012): 89–92. http://dx.doi.org/10.17816/kmj2154.

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Aim. To study the peculiarities of external respiratory functioning in boys of 8, 9 and 10 years in various periods of the academic year at rest, after a dosed dynamic and static loads. Methods. Examined were 38 practically healthy boys with an average level of physical development. Observation was conducted in three age groups of boys: 8, 9 and 10 years. The functional state of the respiratory system was assessed by the magnitude of lung volumes and ventilation parameters. The test with an isometric load was performed in a sitting position by squeezing a dynamometer in the left hand with a fo
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Walter, Dal Negro Roberto, Turco Paola, and Povero Massimiliano. "Phenotyping lung function disorders in respiratory Long-COVID." British Journal of Multidisciplinary and Advanced Studies 4, no. 3 (2023): 71–83. http://dx.doi.org/10.37745/bjmas.2022.0219.

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Dyspnea is frequently complained for several weeks in Long-COVID, still being its underlying pathophysiology poorly investigated in the clinical setting. Aim: to investigate the lung functional pattern of Long-COVID patients and healthy controls (HC). Non-smokers aged ≥18years, discharged after COVID pneumonia were investigated, were classified as low dyspnea scorers (LDS) or high dyspnea scorers (HDS) if they were not complaining or otherwise still complaining dyspnea 12-16 weeks after discharge. A group of non-smoking HC was compared. Spirometric parameters; usual DLCO; simultaneous single-b
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