Academic literature on the topic 'Respiratory therapy'

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Journal articles on the topic "Respiratory therapy"

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Krylov, Krylov V. V., Petrikov S. S. Petrikov, Solodov A. A. Solodov, Mekhia Mekhia E. D. Mekhia, and Malyavin A. G. Malyavin. "Respiratory rehabilitation: modern methods of separation of the patient from the respirator." Therapy 5_2019 (October 11, 2019): 104–10. http://dx.doi.org/10.18565/therapy.2019.5.104-110.

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Krylov, Krylov V. V., Petrikov S. S. Petrikov, Solodov A. A. Solodov, Mekhia Mekhia E. D. Mekhia, and Malyavin A. G. Malyavin. "Respiratory rehabilitation: modern methods of separation of the patient from the respirator." Therapy 5_2019 (October 11, 2019): 104–11. http://dx.doi.org/10.18565/therapy.2019.5.104-111.

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&NA;. "RESPIRATORY THERAPY." American Journal of Nursing 96, no. 1 (January 1996): 10. http://dx.doi.org/10.1097/00000446-199601000-00005.

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Peck, Michael Mc. "Respiratory Therapy." Journal of Aerosol Medicine 5, no. 2 (January 1992): 123. http://dx.doi.org/10.1089/jam.1992.5.123.

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MATHEWS, PAUL J. "RESPIRATORY THERAPY." Nursing 19, no. 4 (April 1989): 98–101. http://dx.doi.org/10.1097/00152193-198904000-00040.

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Vengerov, Vengerov Yu Ya, Kulagina M. G. Kulagina, and Nagibina M. V. Nagibina. "Acute respiratory infection." Therapy 4_2021 (May 3, 2021): 95–100. http://dx.doi.org/10.18565/therapy.2021.4.95-100.

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Carswell, F. "Pediatric Respiratory Therapy." Archives of Disease in Childhood 61, no. 11 (November 1, 1986): 1149. http://dx.doi.org/10.1136/adc.61.11.1149-a.

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Conway, Mary Ellen, Tim Pontius, and David Abalos. "Home respiratory therapy." Case Manager 8, no. 5 (September 1997): 65–67. http://dx.doi.org/10.1016/s1061-9259(97)80019-7.

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Fields, Alan I. "PEDIATRIC RESPIRATORY THERAPY." Chest 91, no. 2 (February 1987): 18. http://dx.doi.org/10.1016/s0012-3692(16)47292-2.

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McPherson, S. P., and C. B. Spearman. "Respiratory Therapy Equipment." Journal of Clinical Engineering 12, no. 3 (May 1987): 174. http://dx.doi.org/10.1097/00004669-198705000-00005.

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Dissertations / Theses on the topic "Respiratory therapy"

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Wijesinghe, Meme. "Oxygen therapy in respiratory disorders." Thesis, Queen Mary, University of London, 2012. http://qmro.qmul.ac.uk/xmlui/handle/123456789/2511.

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Oxygen therapy remains a cornerstone of medical practice and is generally regarded as being safe. However, there is a lack of clinical evidence to support the routine use of oxygen therapy, and in certain conditions, injudicious oxygen may cause harm. In this thesis, I will present two audits and three randomised controlled trials of oxygen therapy. Methods  A prospective audit of the prescription and use of oxygen therapy before and after the introduction of an oxygen prescription section on a drug chart  A retrospective audit of ambulance oxygen administration, in patients with acute exacerbations of chronic obstructive pulmonary disease (AECOPD)  Two randomised controlled trials of high flow versus titrated oxygen in 150 patients with community acquired pneumonia and 106 patients with acute severe asthma  A randomised controlled trial of 24 subjects with obesity hypoventilation syndrome (OHS) comparing 100% oxygen with air Results  Oxygen prescription is suboptimal in hospital inpatients. Whilst an oxygen prescription section improved prescription, this intervention did not improve clinical practice  Over 70% of patients presenting with AECOPD received high flow oxygen prior to presentation to the emergency department. The risk of adverse outcomes increased progressively with increased PaO2  High concentration oxygen leads to a rise in PaCO2 compared to titrated oxygen, when administered to patients presenting with asthma or pneumonia  Breathing 100% oxygen leads to a rise in PaCO2 in patients with OHS Conclusion This series of studies has shown that further measures are warranted to ensure the safe practice of oxygen therapy in the pre-hospital and hospital setting. In addition, the findings suggest that the potential for high concentration oxygen therapy to increase PaCO2 is not limited to COPD but may occur in other respiratory conditions in which abnormal gas exchange or respiratory drive are present.
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Bradley, Kimberley Anne. "Respiratory therapy for speech in multiple sclerosis." Thesis, University College London (University of London), 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.264909.

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Else, Liana. "Lived experiences of professional nurses caring for mechanically ventilated patients." Thesis, Nelson Mandela Metropolitan University, 2015. http://hdl.handle.net/10948/8295.

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Critical care nursing is a speciality that continues to evolve and transform. Critical care nurses of the 21st century routinely care for the complex, critically ill patient, integrating sophisticated technology with the accompanying psychosocial challenges and the ethical conflicts associated with critical illness – while, at the same time, addressing the needs and concerns of the family. Providing nursing care in such a dynamic and fast-track unit can pose various challenges for the critical care nurse. Professional nurses are the backbone of any health-care system. The quality of nursing directly affects the patients’ outcomes, and nursing care must therefore be rendered meticulously. Mechanical ventilator support is routinely needed for critically ill adults in these care units and is also a common therapy in sub-acute and long-term care settings. The care of the mechanically ventilated patient is the core of a professional nurse`s practice in the critical care unit. The mechanically ventilated patient presents many challenges for the professional nurse, while the critical care unit poses as a stressful environment for the professional nurse as well as the patient. The objectives of this study therefore were to explore and describe the lived experiences of professional nurses while caring for mechanically ventilated patients, and to develop recommendations to support professional nurses while caring for mechanically ventilated patients. A qualitative, explorative, descriptive and contextual research design was utilised. Data was collected by means of semi-structured interviews and analysed according to the framework provided by Tesch. Purposive sampling was used to select a sample of professional nurses working in a critical care environment. Guba’s model was utilised to verify data and to ensure trustworthiness of the study. Ethical principles were adhered to throughout this research study. With the analysed data, recommendations were to support professional nurses while caring for mechanically ventilated.
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Perrin, Kyle Gareth. "High concentration oxygen therapy in acute respiratory disease." Thesis, University of Canterbury. Health Sciences Centre, 2010. http://hdl.handle.net/10092/5079.

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Uncontrolled oxygen is often administered to breathless patients regardless of whether hypoxaemia is present. In acute exacerbations of Chronic Obstructive Pulmonary Disease (AECOPD) this may result in carbon dioxide (CO2) retention and worsening respiratory failure in some patients. In AECOPD the main mechanism is the release of hypoxic pulmonary vasoconstriction and an increase in the physiological dead space to tidal volume ratio (VD/VT). Acute asthma and pneumonia have features in common with AECOPD, namely significant ventilation – perfusion mismatch; and there is the potential for CO2 retention to occur if uncontrolled high concentration oxygen is given. There have been no randomised controlled trials of oxygen therapy in pneumonia and only one in asthma. The potential mechanisms of any change in arterial CO2 that may occur with oxygen therapy in respiratory disorders other than COPD remain uncertain. This thesis presents work from three clinical studies. In two randomised controlled trials, high concentration oxygen was compared to titrated oxygen therapy in patients with either acute severe asthma and suspected community acquired pneumonia. Oxygen was administered for one hour in conjunction with standard medical treatment. Transcutaneous CO2 (PtCO2) was continuously monitored and the number of patients with pre-specified increases in PtCO2 were calculated. The proportion of patients with a rise in PtCO2 4 mmHg was significantly higher in the high concentration oxygen groups of both studies. In the pneumonia study 36/72 (50.0%) vs 11/75 (14.7%) met this endpoint, with a relative risk of 3.4 (95% CI 1.9 to 6.2; P <0.001), and in the asthma study 22/50 (44%) vs 10/53 (18.9%) met this endpoint, with a relative risk of 2.3 (95% CI 1.2 to 4.3; P=0.009). Similarly, a rise in PtCO2 8 mmHg was more common with high concentration oxygen. In the pneumonia study 11/72 (15.3%) vs 2/75 (2.7%) of patients met this endpoint, with a relative risk of 5.7 (95% CI 1.3 to 25.0; P=0.007), and 10/50 (20%) vs 3/53 (5.7%) of asthma patients met this endpoint, with a relative risk of 3.6 (95% CI 1.1 to 12.3; P=0.03). A third study measured the physiological response to 20 minutes of 100% oxygen in chronic severe asthma, with comparison to a group of negative controls (normal subjects) and positive controls (COPD patients). There was a significant rise in PtCO2 of similar magnitude in the asthma and COPD groups compared with the normal controls. The mechanism of the PtCO2 rise was similar in asthma and COPD, with an increase in VD/VT but no change in minute ventilation. These studies demonstrate than uncontrolled high concentration oxygen has the potential to cause CO2 retention in respiratory diseases other than COPD, and that in asthma the mechanism of hypercapnia is similar to that in AECOPD. In acute asthma and community-acquired pneumonia oxygen should be administered only to those patients with evidence of arterial hypoxaemia in a dose that relieves hypoxaemia without causing hyperoxia, thereby achieving the benefits of oxygen therapy while reducing the potential for harm.
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Alfadhel, Munerah. "Phage-based therapy for nasal and respiratory infections." Thesis, University of Strathclyde, 2013. http://oleg.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=23059.

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The adoption of therapy based on bacteriophage for the reduction of harboured pathogens is limited by a lack of understanding regarding their formulation as medicines. The product must able to efficiently deliver phage without deterioration and since oral delivery results in the destruction of the lytic activity, a nasal delivery system was investigated. This thesis first describes the formulation of lyophilised nasal inserts carrying a bacteriophage selective for S. aureus, for the eradication of MRSA resident in the nose. Lyophilization of bacteriophages in 1 mL of 1-2% (w/v) hydroxypropyl methylcellulose (HPMC) with or without the addition of 1% (w/v) mannitol yielded nasal inserts composed of a highly porous leaflet-like matrix. The bacteriophage titre fell following lyophilization to 108 pfu per insert, then reduced 100- to 1000-fold over 6 to 12 months storage at 4 oC. The second part of this thesis presented a new phage bioprocess method which involved co-precipitation of a n aqueous mixture of phage and a crystallisable carrier (glutamine or glycine) is described. Inclusion of albumin or trehalose at 5% w/w during co-precipitation provided additional stabilization of the phage. In the third part of this thesis, a lipid vehicle (LamellasomesTM) as a carrier in pulmonary delivery for antibiotics and/or bacteriophage was characterised. We further investigated the potential for co-formulation of antibiotics or bacteriophage by dispersion into LMS and nebulization of aerosolized droplets. Patients with cystic fibrosis (CF) may harbour antibiotic-resistant, mucoid strains of Pseudomonas aeruginosa in the lung. Bacteriophages were carried with the bulk fraction, rather than being selectively carried in larger or smaller aerosols. Dilution of colistin or tobramycin into LMS increased the nebulized drug fraction deposited into stages 2-5. This suggests that the surface activity of the LMS facilitates the generation of smaller aerosol droplets during nebulization. In conclusion, the work reported in this thesis suggests that bacteriophages can be formulated in a stable preparation and therefore have a potential as an alternative therapeutic agent for treatment of resistant bacterial infection on mucous surfaces.
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Slater, Mariel. "Predicting response to Azithromycin therapy in asthma." Thesis, University of Nottingham, 2015. http://eprints.nottingham.ac.uk/14428/.

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Macrolide antibiotics, including Azithromycin (AZM), can improve clinical symptoms in asthma regardless of infection status. Mechanisms underlying these beneficial effects are yet to be fully elucidated. Asthma is associated with a defective airway epithelium with reduced expression of structural proteins and aberrant repair responses. In vitro, AZM has shown anti-inflammatory and anti-viral actions, as well as enhancement of airway cell barrier integrity. Therefore, it was hypothesised that the beneficial effects of AZM in asthma may involve barrier reinforcement. The main aims were to determine the effects of AZM on airway epithelial function in vitro, in vivo and ex vivo. Primary normal human bronchial epithelial cells (HBEC) were differentiated in vitro through an air liquid interface. Severe asthma patients were administered 250mg daily AZM for 6 weeks, with clinical outcome measures and bronchoscopy pre- and post-AZM. Addition of AZM to HBEC in vitro enhanced the development of a differentiating epithelial barrier over 14 days, which was accompanied by reduced permeability, increased thickness, reduced mucin expression and suppressed endogenous release of MMP-9. Importantly, MMP-9 levels inversely correlated with barrier integrity, providing a putative mechanism. Clinical measures from 10 asthma patients were heterogeneous both pre- and post-AZM. Overall, symptoms, lung function and inflammation did not significantly alter and there was no association between clinical measures and the epithelial barrier of bronchial biopsies. The current findings suggest that AZM aids in HBEC barrier formation in vitro. This novel finding may relate to the beneficial effects of AZM reported in vivo e.g. through reducing susceptibility to damage and inflammation during re-epithelisation. This could not be confirmed in vivo due to the low number of samples obtained. The current findings add further evidence towards the beneficial non-antibacterial effects of AZM and may have implications for the prospective targeting of the epithelium for clinical benefit in asthma.
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Hixon, Sally J. "An investigation of the psychometric properties of a clinical simulation examination for respiratory care practitioners /." The Ohio State University, 1985. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487261919111437.

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McHenry, Kristen L. "New Faculty Mentoring in Respiratory Care." Digital Commons @ East Tennessee State University, 2018. https://dc.etsu.edu/etsu-works/5444.

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McHenry, Kristen L. "Respiratory Therapists as Physician Extenders: Perceptions of Practitioners and Educators." Digital Commons @ East Tennessee State University, 2015. https://dc.etsu.edu/etsu-works/2542.

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Donne, Adam. "Investigations into recurrent respiratory papillomatosis and the evaluation of current therapy." Thesis, University of Manchester, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.678786.

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Books on the topic "Respiratory therapy"

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B, Spearman Charles, ed. Respiratory therapy equipment. 3rd ed. St. Louis: C.V. Mosby Co., 1985.

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B, Spearman Charles, ed. Respiratory therapy equipment. 4th ed. St. Louis: Mosby, 1990.

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Corporation, Springhouse, ed. Respiratory drug therapy. Springhouse, Pa: Springhouse, 1995.

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D, Lough Marvin, Doershuk Carl F. 1930-, and Stern Robert C. 1938-, eds. Pediatric respiratory therapy. 3rd ed. Chicago: Year Book Medical Publishers, 1985.

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Jacob, Boe, O'Driscoll B. Ronan, and Dennis John H, eds. Practical handbook of nebulizer therapy. London: Martin Dunitz, 2004.

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Canada, Canada Health and Welfare. Respiratory therapy service: Guidelines. Ottawa: Health and Welfare Canada, 1987.

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1954-, Parsons Polly E., and Heffner John E, eds. Pulmonary/respiratory therapy secrets. Philadelphia: Hanley & Belfus, 1996.

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1954-, Parsons Polly E., and Heffner John E, eds. Pulmonary/respiratory therapy secrets. 3rd ed. Philadelphia: Mosby-Elsevier, 2006.

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Federal-Provincial Advisory Committee on Institutional and Medical Services (Canada). Subcommittee on Institutional Program Guidelines. Respiratory therapy service: Report. Ottawa: Health Services Directorate, Health Services and Promotion Branch, 1987.

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White, Gary C. Equipment theory for respiratory care. 3rd ed. Albany, N.Y: Delmar Publishers, 1999.

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Book chapters on the topic "Respiratory therapy"

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Iñiguez Osmer, Fernando, and Viviana Aguirre Camposano. "Inhalation Therapy." In Pediatric Respiratory Diseases, 633–42. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-26961-6_61.

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Zamorano Wittwer, Alejandra, and Claudia Astudillo Maggio. "Oxygen Therapy." In Pediatric Respiratory Diseases, 675–81. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-26961-6_66.

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Bhatt, Jayesh, and Sarah Spencer. "Oxygen Therapy." In Children's Respiratory Nursing, 55–72. West Sussex, UK: John Wiley & Sons, Ltd,., 2013. http://dx.doi.org/10.1002/9781118702680.ch6.

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Silver, David A. "Respiratory Therapy Devices." In Practical Handbook of Thoracic Anesthesia, 209–19. Boston, MA: Springer US, 2011. http://dx.doi.org/10.1007/978-0-387-88493-6_12.

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Starkel, Julie L., Christina Stapke, Abigail Stanley-O’Malley, and Diana Noland. "Respiratory." In Integrative and Functional Medical Nutrition Therapy, 927–68. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-30730-1_51.

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Tsuchida, Takaaki, and Takehiro Izumo. "Photodynamic Therapy for Lung Cancer." In Respiratory Endoscopy, 229–41. Singapore: Springer Singapore, 2016. http://dx.doi.org/10.1007/978-981-287-916-5_29.

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Lehrer, Paul M. "Biofeedback Therapy for Asthma." In Functional Respiratory Disorders, 179–205. Totowa, NJ: Humana Press, 2012. http://dx.doi.org/10.1007/978-1-61779-857-3_10.

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Onishi, Hiroshi. "Respiratory Motion Management." In Stereotactic Body Radiation Therapy, 91–102. Tokyo: Springer Japan, 2015. http://dx.doi.org/10.1007/978-4-431-54883-6_7.

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Blair, E., G. Darby, G. Gough, E. Littler, D. Rowlands, and M. Tisdale. "Chemotherapy of respiratory virus infections." In Antiviral Therapy, 71–95. London: Garland Science, 2023. http://dx.doi.org/10.1201/9781003423744-4.

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Tin, Win. "Oxygen Therapy." In Manual of Neonatal Respiratory Care, 59–63. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-39839-6_6.

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Conference papers on the topic "Respiratory therapy"

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Hussain, Syed Fayyaz, Nur Najah Binti Mahmood, and Maheen Gill. "Confidence among respiratory and non-respiratory ward staff in administering oxygen therapy." In ERS International Congress 2017 abstracts. European Respiratory Society, 2017. http://dx.doi.org/10.1183/1393003.congress-2017.pa2591.

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Mngwengwe, Luleka, Masixole Y. Lugongolo, Saturnin S. Ombinda-Lemboumba, Yaseera Ismail, and Patience T. Mthunzi-Kufa. "The effect of low-level laser therapy on severe acute respiratory syndrome coronavirus-2 infected cells." In Mechanisms of Photobiomodulation Therapy XVII, edited by James D. Carroll, Ann Liebert, and Jeri-Anne Lyons. SPIE, 2024. http://dx.doi.org/10.1117/12.3002453.

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Mngwengwe, Luleka, Masixole Y. Lugongolo, Saturnin S. Ombinda-Lemboumba, Yaseera Ismail, and Patience T. Mthunzi-Kufa. "HEK293/ACE2 cells' response to severe acute respiratory syndrome coronavirus-2 infection and low-level-laser therapy under microscopy." In Mechanisms of Photobiomodulation Therapy XVII, edited by James D. Carroll, Ann Liebert, and Jeri-Anne Lyons. SPIE, 2024. http://dx.doi.org/10.1117/12.3002406.

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Nolasco, Santi, Raffaele Campisi, Pietro Impellizzeri, Stefano Alia, Nunzio Crimi, Carlo Vancheri, Francesco Blasi, Stefano Aliberti, and Claudia Crimi. "Impact of Long-term Home High-Flow Nasal Therapy on Mucus Plugs in Patients with Bronchiectasis." In Respiratory Failure and Mechanical Ventilation Conference 2024 abstracts. European Respiratory Society, 2024. http://dx.doi.org/10.1183/23120541.rfmv-2024.56.

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Yarmolchy, Y. A., T. S. Chikova, E. V. Emelianenko, and M. N. Piatkevich. "APPLICATION OF RESPIRATORY GATING SYSTEMS FOR DIAGNOSIS AND TREATMENT OF ONCOLOGICAL DISEASES." In SAKHAROV READINGS 2022: ENVIRONMENTAL PROBLEMS OF THE XXI CENTURY. International Sakharov Environmental Institute of Belarusian State University, 2022. http://dx.doi.org/10.46646/sakh-2022-2-223-226.

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Respiratory gating systems are successfully used for the diagnosis and treatment of oncological diseases. Their use increases the accuracy of radiation therapy, which is especially important when delivering high doses to cancerous tumors, as is the case with stereotactic radiation therapy. The use of respiratory gating systems systems in cooperation with CT allows you to more accurately determine the position of the tumor and outline its boundaries, which reduces the error in further treatment with radiation therapy. Respiratory gating systems are used in the treatment of tumors of the left breast, since their use reduces the dose load on the heart.
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Pešek, Miloš, Lucie Zdrhova, Radka Bittenglova, Terezie Turkova-Sedlackova, Karel Balihar, and Peter W. Dettmar. "Extraesophageal reflux (EER)—diagnostics and therapy in respiratory patients." In ERS International Congress 2017 abstracts. European Respiratory Society, 2017. http://dx.doi.org/10.1183/1393003.congress-2017.pa740.

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Essay, P., C. Vicera, J. Mosier, and V. Subbian. "Analysis of Acute Respiratory Failure Patient Noninvasive Ventilation Therapy." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a1579.

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Garner, Nicola, Paul Deegan, Hassan Burhan, and Ida Ryland. "Ascertaining baseline knowledge of oxygen therapy and respiratory failure." In ERS International Congress 2016 abstracts. European Respiratory Society, 2016. http://dx.doi.org/10.1183/13993003.congress-2016.pa1624.

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Allwyn Gnanadas, A., S. Hamshavarthini, K. V. Rithanya, P. Kaviya, and S. Isabella. "Nebulizer Add-Ons: Innovative Features for Improved Respiratory Therapy." In 2023 7th International Conference on Electronics, Communication and Aerospace Technology (ICECA). IEEE, 2023. http://dx.doi.org/10.1109/iceca58529.2023.10395303.

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Shaaban, Lamia, Shereen Farghaly, Ashraf Zin El-Abdeen, Hanan Galal, and Entsar Mohammed. "Short-term systemic steroid therapy in chronic obstructive pulmonary disease patients with acute respiratory failure." In ERS Respiratory Failure and Mechanical Ventilation Conference 2020 abstracts. European Respiratory Society, 2020. http://dx.doi.org/10.1183/23120541.rfmvc-2020.42.

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Reports on the topic "Respiratory therapy"

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Kim, Jae G. Respiratory Challenges in Breast Cancer: Potential for Enhanced Diagnostics and Therapy. Fort Belvoir, VA: Defense Technical Information Center, July 2010. http://dx.doi.org/10.21236/ada542555.

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Sanguanwong, Natthawan, Nattawat Jantarangsi, Natthida Owattanapanich, and Vorakamol Phoophiboon. Effect of non-invasive ventilation and high flow nasal cannula on interstitial lung disease with acute respiratory failure: A systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, June 2022. http://dx.doi.org/10.37766/inplasy2022.6.0104.

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Review question / Objective: P: Interstitial lung disease patient who is suffering with acute respiratory failure. I: Non-invasive oxygen therapy either non-invasive ventilation (NIV) or high flow nasal cannula (HFNC). C: 1. Conventional oxygen therapy, 2. NIV vs HFNC. O: P/F ratio improvement, PaCO2 reduction, mortality, intubation rate. Condition being studied: The benefit of using either non-invasive ventilation or high flow nasal cannula on interstitial lung disease with acute respiratory failure.
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Byrne, Barry J. Advanced Gene Therapy for Treatment of Cardiomyopathy and Respiratory Insufficiency in Duchenne Muscular Dystrophy. Fort Belvoir, VA: Defense Technical Information Center, September 2014. http://dx.doi.org/10.21236/ada613171.

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Kuzmin, Vyacheslav, Alexander Kulikov, Alexander Levit, Vladimir Rudnov, Alabai Sabitov, and Rustam Mukhametshin. Electron training course "Intensive therapy of acute respiratory failure in the conditions of a coronavirus pandemic". SIB-Expertise, December 2022. http://dx.doi.org/10.12731/er0653.15122022.

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Актуальность дополнительной профессиональной образовательной программы повышения квалификации врачей по теме «Интенсивная терапия острой дыхательной недостаточности в условиях коронавирусной пандемии» обусловлена необходимостью обучения специалистов здравоохранения навыкам своевременного выявления, диагностики и оказания медицинской помощи пациентам, инфицированным COVID-19
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Wang, Xiaoyu. Pediatric tuina in treating recurrent respiratory tract infection in children: a systematic review and meta‑analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, April 2023. http://dx.doi.org/10.37766/inplasy2023.4.0075.

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Review question / Objective: Is pediatric tuina an effective treatment for recurrent respiratory tract infection in children? Condition being studied: Recurrent respiratory tract infection (RRTI) is a common disease in children, which refers to the recurrence of upper and lower respiratory tract infections within a year, exceeding the prescribed number of times. It is more common in infants under 3 years old. The disease is easy to relapse and lasts for a long time, affecting the normal growth and development of children and physical and mental health, easily causing other diseases, leading to a variety of chronic wasting diseases, and damaging the function of organs and the immune system. Immunotherapy and nutritional therapy are commonly used in Western medicine. At present, the treatment of RRTI in children with traditional Chinese medicine has achieved a certain effect, and the treatment mainly includes internal treatment and external treatment. Tuina therapy is one of the common therapies for the treatment of RRTI in children with traditional Chinese medicine. Because of its advantages, there are many literature reports on tuina treatment of this disease, with a good total effective rate, but whether its therapeutic effect is higher than other therapies has not been determined as a whole. This study used the method of systematic review to collect the published clinical research literature on the treatment of RRTI in children at home and abroad for systematic review, so as to provide a reference for clinical research.
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Xing, Lei, Hongmin Guo, and Zhiqian Wang. Efficacy and safety of Suzi Jiangqi Decoction in patients with acute exacerbation of chronic obstructive pulmonary disease A protocol for systematic review and meta analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, August 2021. http://dx.doi.org/10.37766/inplasy2021.8.0035.

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Background: Chronic obstructive pulmonary disease (COPD) is characterized by chronic respiratory symptoms. The respiratory symptoms of patients with acute exacerbation of COPD (AECOPD) worsen rapidly. At present, traditional western medicine treatment can not effectively alleviate the symptoms and attack frequency of patients. Suzi Jiangqi decoction(SZJQ) has a good clinical effect in the treatment of AECOPD. Due to the lack of evidence-based medicine, it can not provide an effective systematic evaluation for the treatment of AECOPD with Suzi Jiangqi decoction. Therefore, it is necessary to provide high-quality evidence evaluation for the clinical efficacy and safety of Suzi Jiangqi Decoction in the treatment of AECOPD. Methods: Two researchers independently retrieved randomized controlled trial (RCT) and quasi-RCTs of SZJQ in the treatment of AECOPD from databases including PubMed, Web of science, the Cochrane Library, CBM, CNKI, Sinomed, VIP and WanFang.The included studies were evaluated for quality according to the RCT quality assessment method provided by Cochrane Reviewer's Handbook 5.3.Review Manager 5.3 software provided by the Cochrane collaboration was used for meta-analysis. Results: This study will provide systematic review on the efficacy and safety of SZJQ as adjuvant therapy in patients with AECOPD by rigorous quality assessment and reasonable data synthesis. Conclusions: This systematic review will provide the good evidence currently on SZJQ as adjuvant therapy in patients with AECOPD.
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Liu, Lu, Wenchuan Qi, Qian Zeng, Ziyang Zhou, Daohong Chen, Lei Gao, Bin He, Dingjun Cai, and Ling Zhao. Does acupuncture improve lung function in chronic obstructive pulmonary disease animal model?: a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, March 2022. http://dx.doi.org/10.37766/inplasy2022.3.0104.

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Review question / Objective: Chronic obstructive pulmonary disease (COPD) is a common, preventable, and treatable disease characterized by persistent respiratory symptoms and progressive airflow obstruction documented on spirometry. Acupuncture, as a safe and economical non-pharmacology therapy, has pronounced therapeutic effects in COPD patients. Several systematic reviews draw the conclusion that acupuncture could improve patients’ quality of life, exercise capacity and dyspnoea, however, the results about lung function were inconclusive. Recently, increasing number of animal studies has been published to illustrate the effects of acupuncture in improving lung function in COPD animal model. However, the efficacy of acupuncture for experimentally induced COPD have not been systematically investigated yet. A systematic review of animal experiments can benefit future experimental designs, promote the conduct and report of basic researches and provide some guidance to translate the achievements of basic researches to clinical application in acupuncture for COPD. Therefore, we will conduct this systematic review and meta-analysis to evaluate effects of acupuncture on COPD animal model.
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Treadwell, Jonathan R., Mingche Wu, and Amy Y. Tsou. Management of Infantile Epilepsies. Agency for Healthcare Research and Quality (AHRQ), October 2022. http://dx.doi.org/10.23970/ahrqepccer252.

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Objectives. Uncontrolled seizures in children 1 to 36 months old have serious short-term health risks and may be associated with substantial developmental, behavioral, and psychological impairments. We evaluated the effectiveness, comparative effectiveness, and harms of pharmacologic, dietary, surgical, neuromodulation, and gene therapy treatments for infantile epilepsies. Data sources. We searched Embase®, MEDLINE®, PubMed®, the Cochrane Library, and gray literature for studies published from January 1, 1999, to August 19, 2021. Review methods. Using standard Evidence-based Practice Center methods, we refined the scope and applied a priori inclusion criteria to the >10,000 articles identified. We ordered full text of any pediatric epilepsy articles to determine if they reported any data on those age 1 month to <36 months. We extracted key information from each included study, rated risk of bias, and rated the strength of evidence. We summarized the studies and outcomes narratively. Results. Forty-one studies (44 articles) met inclusion criteria. For pharmacotherapy, levetiracetam may cause seizure freedom in some patients (strength of evidence [SOE]: low), but data on other medications (topiramate, lamotrigine, phenytoin, vigabatrin, rufinamide, stiripentol) were insufficient to permit conclusions. Both ketogenic diet and the modified Atkins diet may reduce seizure frequency (SOE: low for both). In addition, the ketogenic diet may cause seizure freedom in some infants (SOE: low) and may be more likely than the modified Atkins diet to reduce seizure frequency (SOE: low). Both hemispherectomy/hemispherotomy and non-hemispheric surgical procedures may cause seizure freedom in some infants (SOE: low for both), but the precise proportion is too variable to estimate. For three medications (levetiracetam, topiramate, and lamotrigine), adverse effects may rarely be severe enough to warrant discontinuation (SOE: low). For topiramate, non-severe adverse effects include loss of appetite and upper respiratory tract infection (SOE: moderate). Harms of diets were sparsely reported. For surgical interventions, surgical mortality is rare for functional hemispherectomy/hemispherotomy and non-hemispheric procedures (SOE: low), but evidence was insufficient to permit quantitative estimates of mortality or morbidity risk. Hydrocephalus requiring shunt placement after multilobar, lobar, or focal resection is uncommon (SOE: low). No studies assessed neuromodulation or gene therapy. Conclusions. Levetiracetam, ketogenic diet, modified Atkins diet, and surgery all appear to be effective for some infants. However, the strength of the evidence is low for all of these modalities due to lack of control groups, low patient enrollment, and inconsistent reporting. Future studies should compare different pharmacologic treatments and compare pharmacotherapy with dietary therapy. Critical outcomes underrepresented in the literature include quality of life, sleep outcomes, and long-term development.
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Heated, humidified high-flow oxygen therapy may be a useful alternative to other forms of respiratory support for preterm babies. National Institute for Health Research, December 2015. http://dx.doi.org/10.3310/signal-000159.

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