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1

Seabra Gomes, Ricardo, Pedro de Araújo Gonçalves, Rui Campante Teles, and Manuel de Sousa Almeida. "Avaliação tardia (> 10 anos) da braquiterapia intracoronária com radiação beta para restenose difusa intrastent." Revista Portuguesa de Cardiologia 33, no. 10 (2014): 609–16. http://dx.doi.org/10.1016/j.repc.2014.02.027.

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2

H, Gutiérrez-Leonar, Aguilar-Oliva R, Galván-Vargas CG, et al. "Angiographic evaluation of intrastent restenosis in patients treated with bioabsorbable stent, medicated stent and medicated balloon." Revista de Sanidad Militar 71, no. 1 (2017): 61–68. http://dx.doi.org/10.56443/rsm.v71i1.79.

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BACKGROUND: Coronary stent restenosis is a neointimal hyperplasia, which leads to the obstruction of the previously treated lesion. Its incidence is around 10%. The treatment is a new intervention with balloon angioplasty and implantation of a new stent to reestablish blood flow. OBJECTIVE: To determine if there is a difference between the different treatment strategies against intrastent restenosis such as the bioabsorbable endoprosthesis, drug-eluting stent and drug-eluting balloon, evaluated by angiography after 12 months of being treated an intrastent stenosis. MATERIALS AND METHODS: Obser
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3

Setacci, Carlo, Emiliano Chisci, Francesco Setacci, Francesca Iacoponi, and Gianmarco de Donato. "Grading Carotid Intrastent Restenosis." Stroke 39, no. 4 (2008): 1189–96. http://dx.doi.org/10.1161/strokeaha.107.497487.

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4

Bajeu, Ioan-Teodor, Adelina-Gabriela Niculescu, Alexandru Scafa-Udriște, and Ecaterina Andronescu. "Intrastent Restenosis: A Comprehensive Review." International Journal of Molecular Sciences 25, no. 3 (2024): 1715. http://dx.doi.org/10.3390/ijms25031715.

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The primary objective of this paper is to delineate and elucidate the contemporary advancements, developments, and prevailing trajectories concerning intrastent restenosis (ISR). We aim to provide a thorough overview of the most recent developments in this area, covering various aspects such as pathophysiological insights, therapeutic approaches, and new strategies for tackling the complex challenges of ISR in modern clinical settings. The authors have undertaken a study to address a relatively new medical challenge, recognizing its significant impact on the morbidity and mortality of individu
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5

Millisani, Hayla Iqda, Indra Prasetya, and Mohammad Saifur Rohman. "Correlation between HbA1c levels and intrastent restenosis incidence in patients with diabetes mellitus after percutaneous coronary intervention at Dr. Saiful Anwar General Hospital." Heart Science Journal 5, no. 4 (2024): 60–64. http://dx.doi.org/10.21776/ub.hsj.2024.005.04.10.

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Correlation between HbA1c levels and intrastent restenosis incidence in patients with diabetes mellitus after percutaneous coronary intervention at Dr. Saiful Anwar General Hospital Keyword: diabetes mellitus, HbA1c, in-stent restenosis, percutaneous coronary intervention
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Freitas Jr, João Orávio de, Sérgio Luis Berti, José Geraldo Bonfá, Maria Sílvia Martins Speranza, Pércio Primo Gandolphi, and Hércules Lisboa Bongiovani. "Cutting balloon angioplasty for intrastent restenosis treatment." Arquivos Brasileiros de Cardiologia 72, no. 5 (1999): 618–20. http://dx.doi.org/10.1590/s0066-782x1999000500009.

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7

Chow, Wing-Hing, and T. F. Chan. "Pullback atherectomy for the treatment of intrastent restenosis." Catheterization and Cardiovascular Diagnosis 41, no. 1 (1997): 94–95. http://dx.doi.org/10.1002/(sici)1097-0304(199705)41:1<94::aid-ccd21>3.0.co;2-p.

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8

Setacci, C., E. Chisci, and F. Setacci. "Grading Carotid Intrastent Restenosis: A Six-Year Follow-Up Study." Journal of Vascular Surgery 48, no. 1 (2008): 247. http://dx.doi.org/10.1016/j.jvs.2008.05.052.

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9

Moneta, G. L. "Grading Carotid Intrastent Restenosis: A 6-Year Follow-Up Study." Yearbook of Vascular Surgery 2009 (January 2009): 55–56. http://dx.doi.org/10.1016/s0749-4041(08)79015-8.

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10

Choho, Zakaria, Tanae El Ghali, Walid Ben Brahim, Fatima Azzahra Benmessaoud, and Latifa Oukerraj. "CORONARY IN-STENT RESTENOSIS: A LITERATURE REVIEW." International Journal of Advanced Research 11, no. 09 (2023): 1440–48. http://dx.doi.org/10.21474/ijar01/17667.

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Intrastent restenosis is a narrowing of the lumen of a coronary vessel previously treated with angioplasty It is the result of two histopathological processes: vascular remodeling and neointimal hyperplasia due to smooth muscle migration and proliferation, with the latter mechanism predominating. It manifests clinically with symptoms of ischemia and angiographic findings showing at least a 50% reduction in the lumen of a vessel previously treated with balloon angioplasty or a stent. Second generation drug eluting stents or drug eluting balloons are recommended for treatment, depending on the t
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11

Schiele, F. "Assessment of Balloon Angioplasty in Intrastent Restenosis With Intra Coronary Ultrasound." Journal of the American College of Cardiology 31, no. 2 (1998): 495A—496A. http://dx.doi.org/10.1016/s0735-1097(97)88158-2.

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12

Schiele, F., N. Meneveau, A. Vuillemenot, et al. "Assessment of balloon angioplasty in intrastent restenosis with intra coronary ultrasound." Journal of the American College of Cardiology 31 (February 1998): 495–96. http://dx.doi.org/10.1016/s0735-1097(98)80509-3.

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13

Montelione, Nunzio, Francesco Stilo, Pasqualino Sirignano, et al. "IP117. Symptomatic Intrastent Carotid Restenosis: A Double-Center Experience With Carotid Bypass." Journal of Vascular Surgery 65, no. 6 (2017): 86S—87S. http://dx.doi.org/10.1016/j.jvs.2017.03.162.

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14

Robertson, Cameron, Ramon L. Varcoe, Stephen Black, and Shannon D. Thomas. "Histopathology of Iliocaval Venous In-Stent Restenosis Treated With Directional Atherectomy." Journal of Endovascular Therapy 26, no. 5 (2019): 742–46. http://dx.doi.org/10.1177/1526602819857240.

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Purpose: To report the use of directional atherectomy to treat venous in-stent restenosis (ISR) and subsequent histopathological analysis of retrieved intrastent tissue. Case Report: A 55-year-old man presented with recurrent symptoms of venous congestion following iliofemoral stenting. The stents were found to be occluded on imaging. Directional atherectomy was used to recanalize the iliofemoral venous stents, which provided significant symptom relief. Tissue retrieved from within the stent demonstrated patterns of cellular components similar to arterial ISR. At 6-month follow-up, the stents
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15

Albuquerque, Felipe C., Elad I. Levy, Aquilla S. Turk, et al. "ANGIOGRAPHIC PATTERNS OF WINGSPAN IN-STENT RESTENOSIS." Neurosurgery 63, no. 1 (2008): 23–28. http://dx.doi.org/10.1227/01.neu.0000335067.53190.a2.

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ABSTRACT OBJECTIVE A classification system developed to characterize in-stent restenosis (ISR) after coronary percutaneous transluminal angioplasty with stenting was modified and applied to describe the appearance and distribution of ISR occurring after Wingspan (Boston Scientific, Fremont, CA) intracranial percutaneous transluminal angioplasty with stenting. METHODS A prospective, intention-to-treat, multicenter registry of Wingspan treatment for symptomatic intracranial atherosclerotic disease was maintained. Clinical and angiographic follow-up results were recorded. ISR was defined as great
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16

Garriboli, Luca, Tommaso Miccoli, Gianguido Pruner, and Antonio Maria Jannello. "PTA and Stenting of Femoropopliteal Trunk With Cordis Smartflex Stent System: A Single-Center Experience." Vascular and Endovascular Surgery 54, no. 1 (2019): 17–24. http://dx.doi.org/10.1177/1538574419875551.

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Introduction: The aim of this study is to describe our experience in the treatment of femoropopliteal occlusive disease with percutaneous transluminal angioplasty (PTA) followed by stenting with S.M.A.R.T. Flex vascular stent system. Materials and Methods: From June 2014 to October 2018, 80 patients were treated at our Institution for intermittent claudication, critical, or acute limb ischemia due to total occlusion or long diffused lesions of the femoropopliteal segment. Main study end points are primary patency, target lesion revascularization, and stent fractures; secondary end points are m
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17

Pascual Andréu, Juan Carlos. "Prevención secundaria de restenosis Intrastent: Transición de cuidados de enfermería al alta hospitalaria." Publicación Científica de la Asociación Española en Enfermería en Cardiología XXX, no. 90 (2023): 40–49. http://dx.doi.org/10.59322//90.4049.lc5.

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A pesar de los avances en el diseño de stent para el tratamiento percutáneo de la enfermedad coronarias severa, aún no se ha logrado la combinación de fármacos, plataformas y recubrimientos que permitan eliminar por completo la reestenosis del stent a largo plazo, precisando un tratamiento de doble antiagregante plaquetario como medida preventiva en la aparición de un nuevo evento coronario, que no es tan infrecuente, ni tan benigno. Junto con el desarrollo de medidas como elección del stent, emplear técnicas minuciosas adaptadas al tipo de lesión y tratamiento antitrombótico ajustado a las ci
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18

Pascual Andréu, Juan Carlos. "Prevención secundaria de restenosis Intrastent: Transición de cuidados de enfermería al alta hospitalaria." Publicación Científica de la Asociación Española en Enfermería en Cardiología XXX, no. 90 (2023): 40–49. http://dx.doi.org/10.59322/90.4049.lc5.

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A pesar de los avances en el diseño de stent para el tratamiento percutáneo de la enfermedad coronarias severa, aún no se ha logrado la combinación de fármacos, plataformas y recubrimientos que permitan eliminar por completo la reestenosis del stent a largo plazo, precisando un tratamiento de doble antiagregante plaquetario como medida preventiva en la aparición de un nuevo evento coronario, que no es tan infrecuente, ni tan benigno. Junto con el desarrollo de medidas como elección del stent, emplear técnicas minuciosas adaptadas al tipo de lesión y tratamiento antitrombótico ajustado a las ci
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19

McMahon, C. J. "Intrastent sonotherapy in pulmonary vein restenosis: a new treatment for a recalcitrant problem." Heart 89, no. 2 (2003): 6e—6. http://dx.doi.org/10.1136/heart.89.2.e6.

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20

Mitomo, Satoru, Francesco Giannini, Luciano Candilio, et al. "Intrastent Hematoma After Pre-Dilatation for 17-Month Restenosis of Polytetrafluoroethylene-Covered Stent." JACC: Cardiovascular Interventions 10, no. 23 (2017): e213-e215. http://dx.doi.org/10.1016/j.jcin.2017.08.046.

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21

Carpinella, G., D. D‘Andrea, F. Furbatto, R. Moscato, F. Serino, and C. Mauro. "P305 MULTIVESSEL SUBACUTE STENT THROMBOSIS." European Heart Journal Supplements 25, Supplement_D (2023): D160—D161. http://dx.doi.org/10.1093/eurheartjsupp/suad111.379.

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Abstract The presence of comorbidities such as psychiatric pathologies negatively influences the prognosis of patients with acute cardiovascular events. A 62–year–old male patient suffering from arterial hypertension, dyslipidemia, ischemic heart disease, treated 3 years earlier with PCI of LAD, Cx e RCA (EF 45%), and schizophrenia, is hospitalized with a diagnosis of NSTEMI. Coronary angiography shows: eccentric stenosis 70% proximal to the pre–existing stent in the middle LAD; Intrastent occlusion of the middle circumflex branch with omocoronary rehabilitation and ulcerated critical plaque i
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22

Napoli, M., R. Prudenzano, E. Sozzo, et al. "Lo stenting nelle stenosi delle fistole arterovenose distali: esperienze preliminari." Giornale di Clinica Nefrologica e Dialisi 24, no. 1 (2018): 40–45. http://dx.doi.org/10.33393/gcnd.2012.1114.

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L'angioplastica percutanea transluminale (PTA) è un efficace trattamento per la correzione delle stenosi delle fistole arterovenose (AFV). Un limite della PTA è l'alta frequenza di recidiva. In teoria lo stenting, prevenendo la restenosi, potrebbe rappresentare la risposta al problema. In letteratura sono limitate tuttavia le esperienze con lo stenting nelle AVF. In questo studio riportiamo la nostra esperienza preliminare in proposito che ha interessato 6 pazienti. Dall'aprile 2008 al dicembre 2011 sono stati posizionati 6 stent su 122 PTA eseguite. Sono stati utilizzati stent me-tallici auto
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23

Alfonso, Fernando, José M. Augé, Javier Zueco, et al. "Long-Term Results (Three to Five Years) of the Restenosis Intrastent: Balloon Angioplasty Versus Elective Stenting (RIBS) Randomized Study." Journal of the American College of Cardiology 46, no. 5 (2005): 756–60. http://dx.doi.org/10.1016/j.jacc.2005.05.050.

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24

Alfonso, F., J. M. Augé, and J. Zueco. "Long-Term Results (Three to Five Years) of the Restenosis Intrastent: Balloon Angioplasty Versus Elective Stenting (RIBS) Randomized Study." ACC Current Journal Review 14, no. 12 (2005): 29–30. http://dx.doi.org/10.1016/j.accreview.2005.11.051.

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25

De Filippo, Ovidio, Matteo Bianco, Matteo Tebaldi, et al. "Angiographic control versus ischaemia-driven management of patients undergoing percutaneous revascularisation of the unprotected left main coronary artery with second-generation drug-eluting stents: rationale and design of the PULSE trial." Open Heart 7, no. 2 (2020): e001253. http://dx.doi.org/10.1136/openhrt-2020-001253.

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BackgroundThe role of planned angiographic control (PAC) over a conservative management driven by symptoms and ischaemia following percutaneous coronary intervention (PCI) of the unprotected left main (ULM) with second-generation drug-eluting stents remains controversial. PAC may timely detect intrastent restenosis, but it is still unclear if this translated into improved prognosis.Methods and analysisPULSE is a prospective, multicentre, open-label, randomised controlled trial. Consecutive patients treated with PCI on ULM will be included, and after the index revascularisation patients will be
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Hikita, Hiroyuki, Shunsuke Kuroda, Naohiko Kawaguchi, et al. "Differential Characteristics of Inflammatory Responses to Stent Implantation Between De Novo and Intrastent Restenosis Lesion in Patients With Stable Angina." Angiology 63, no. 2 (2011): 92–95. http://dx.doi.org/10.1177/0003319711408284.

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Gomez-Recio, Manuel, Cesar Moris, Luis Insa, et al. "1121-54 Implications of the “watermelon seeding” phenomenon during coronary interventions for in-stent restenosis insights from the restenosis intrastent balloon angioplasty versus elective stenting (RIBS) randomized trial." Journal of the American College of Cardiology 43, no. 5 (2004): A78. http://dx.doi.org/10.1016/s0735-1097(04)90325-7.

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28

Tocci, G., R. Coluccia, A. Modestino, et al. "12.24 Coronary Intrastent Restenosis and Blood Pressure Levels: Retrospective Analysis of a Large Cohort of Patients with Coronary Single Vessel Disease." High Blood Pressure & Cardiovascular Prevention 15, no. 3 (2008): 333. http://dx.doi.org/10.1007/bf03263745.

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Tocci, G., A. Modestino, R. Coluccia, et al. "CORONARY INTRASTENT RESTENOSIS AND BLOOD PRESSURE LEVELS: RETROSPECTIVE ANALYSIS OF A LARGE COHORT OF PATIENTS WITH CORONARY SINGLE VESSEL DISEASE: 1C.06." Journal of Hypertension 28 (June 2010): e8. http://dx.doi.org/10.1097/01.hjh.0000378255.81414.b5.

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Gherasie, Flavius-Alexandru, Chioncel Valentin, and Stefan-Sebastian Busnatu. "Is There an Advantage of Ultrathin-Strut Drug-Eluting Stents over Second- and Third-Generation Drug-Eluting Stents?" Journal of Personalized Medicine 13, no. 5 (2023): 753. http://dx.doi.org/10.3390/jpm13050753.

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In patients undergoing percutaneous coronary intervention, the second-generation drug-eluting stents (DES) are considered the gold standard of care for revascularization. By reducing neointimal hyperplasia, drug-eluting coronary stents decrease the need for repeat revascularizations compared with conventional coronary stents without an antiproliferative drug coating. It is important to note that early-generation DESs were associated with an increased risk of very late stent thrombosis, most likely due to delayed endothelialization or a delayed hypersensitivity reaction to the polymer. Studies
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Facci, G., A. Bottardi, G. Venturi, et al. "TO CUT OR NOT TO CUT: CUTTING BALLOON FOR LESION PREPARATION BEFORE DRUG COATED BALLOON ANGIOPLASTY." European Heart Journal Supplements 26, Supplement_2 (2024): ii45. http://dx.doi.org/10.1093/eurheartjsupp/suae036.102.

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Abstract Background There are limited data on the use of DCB in calcified lesions. In particular, evidence regarding the use of cutting balloon before DCB angioplasty is scarce. Methods We retrospectively analyzed our internal registry between May 2017 and May 2023 to retrieve intrastent restenosis angioplasty performed with DCB. We divided our population according to the use of cutting balloon as debulking technique before DCB. The objective of the study was to compare the two population in term of procedural success (primary endpoint defined as absence of flow–limiting dissection or residual
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LaDisa, John F., Lars E. Olson, Ismail Guler, et al. "Circumferential vascular deformation after stent implantation alters wall shear stress evaluated with time-dependent 3D computational fluid dynamics models." Journal of Applied Physiology 98, no. 3 (2005): 947–57. http://dx.doi.org/10.1152/japplphysiol.00872.2004.

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The success of vascular stents in the restoration of blood flow is limited by restenosis. Recent data generated from computational fluid dynamics (CFD) models suggest that stent geometry may cause local alterations in wall shear stress (WSS) that have been associated with neointimal hyperplasia and subsequent restenosis. However, previous CFD studies have ignored histological evidence of vascular straightening between circumferential stent struts. We tested the hypothesis that consideration of stent-induced vascular deformation may more accurately predict alterations in indexes of WSS that may
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33

Taghavi, Maxime, Adrien Lengelé, Marc Laureys, et al. "Antiphospholipid antibodies positivity as a potential risk factor for restenosis following arteriovenous fistula stenting in hemodialysis patients: a pilot study." Frontiers in Medicine 11 (January 3, 2025). https://doi.org/10.3389/fmed.2024.1497810.

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BackgroundThe arteriovenous fistula (AVF) is the preferred vascular access for hemodialysis. AVF stenosis is a common complication, often requiring balloon angioplasty. For recurrent stenosis, AVF stenting may be an option. Persistent antiphospholipid antibody (aPL) positivity is frequently observed in hemodialysis (HD) patients and is associated with AVF thrombosis and stenosis. This study aimed to evaluate AVF stent survival without stenosis in aPL-positive hemodialysis patients.MethodsA monocentric retrospective observational study was conducted on 35 patients who underwent AVF stenting bet
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34

Hong, Xu-Lin, Guo-Sheng Fu, Zhan-Lu Li, and Wen-Bin Zhang. "Intrastent haematoma after treatment with a drug-eluting balloon for in-stent restenosis: a case report." European Heart Journal - Case Reports 5, no. 8 (2021). http://dx.doi.org/10.1093/ehjcr/ytab295.

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Abstract Background Intrastent haematoma after dilatation of in-stent restenosis (ISR) is rarely reported and the optimal treatment for this condition remains unclear. Case summary We present the case of an 87-year-old man with in-stent subtotal occlusion of left circumflex. He experienced chest pain after drug-eluting balloon was released in the stent. Intravascular ultrasound revealed intrastent haematoma, which was not relieved with a cutting balloon but completely sealed by an Endeavor Resolute stent. Discussion Intrastent haematoma after dilatation of ISR is rare. Reimplantation of stent
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35

Basso, P., N. Locuratolo, F. Carrata, et al. "C56 THE IMPACT OF STATIN THERAPY ON THE PROGNOSIS OF PATIENTS DISCHARGED AFTER ACUTE CORONARY SYNDROME: A SUBANALYSIS OF THE APULIA PONTE ACS STUDY." European Heart Journal Supplements 24, Supplement_C (2022). http://dx.doi.org/10.1093/eurheartj/suac011.055.

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Abstract Background The administration of statin therapy in patients who suffered from acute coronary syndrome (ACS) is fundamental in order to avoid recurrences and adverse cardiovascular events. The long–term adherence and persistence on statin therapy is challenging. The aim of this study was to evaluate the prognostic impact of a dedicated follow–up outpatient program for patients who were discharged with the diagnosis of ACS on adherence and persistence on statin therapy. Methods This was a subanalysis of the PONTE ACS study. The PONTE ACS study is a prospective, longitudinal, cohort stud
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Souteyrand, Géraud, Thomas Mouyen, Benjamin Honton, et al. "Stent Underexpansion Is an Underestimated Cause of Intrastent Restenosis: Insights From RESTO Registry." Journal of the American Heart Association, October 25, 2024. http://dx.doi.org/10.1161/jaha.124.036065.

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Background Despite improvement in devices, in‐stent restenosis remains a frequent and challenging complication of percutaneous coronary interventions. Methods and Results The RESTO (Morphological Parameters of In‐Stent Restenosis Assessed and Identified by OCT [Optical Coherence Tomography]; study NCT04268875) was a prospective multicenter registry including patients presenting with coronary syndromes related to in‐stent restenosis. All patients underwent preintervention OCT analysis, which led to analysis of in‐stent restenosis phenotype, number of strut layers, and presence of stent underexp
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Nobile, Edoardo, Aurelio De Filippis, Simone Circhetta, et al. "526 ALAGILLE SYNDROME, A CASE REPORT." European Heart Journal Supplements 24, Supplement_K (2022). http://dx.doi.org/10.1093/eurheartjsupp/suac121.353.

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Abstract Alagille syndrome (AGS) is a dominantly inherited multisystem disorder caused by heterozygous mutations of genes that are components of the Notch signaling pathway. The main clinical manifestations of AGS are intrahepatic bile duct paucity, congenital heart defects involving primarily the pulmonary arteries, butterfly vertebrae, anterior chamber defects of the eye and facial dysmorphism. A male patient of 39 years old came to our observation due to the worsening of dyspnea, cyanosis, dizziness, heartbeat and asthenia for about two years. His cardiological history includes percutaneous
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38

Rabellino, Martín, Pedro N. Moltini, Vanesa G. Di Caro, José G. Chas, Vadim Kotowicz, and Ricardo D. García-Mónaco. "Resultado clínico del tratamiento endovascular con balón liberador de fármaco en el paciente claudicante con enfermedad femoropoplítea." Revista Argentina de Cardiología, June 10, 2025. https://doi.org/10.7775/rac.es.v86.i4.10539.

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Introducción: La restenosis continúa siendo el gran desafío de la terapia endovascular, por esa razón, se han desarrollado balones liberadores de fármaco (BLF) con la finalidad de reducir la restenosis. El objetivo de este trabajo es analizar los resultados de esta terapia. Material y métodos: Se realizó un análisis retrospectivo de 40 extremidades de pacientes claudicantes con lesiones femoropoplíteas tratados con BLF. Resultados: Se obtuvo el éxito técnico en las 40 (100%) extremidades tratadas con una media de seguimiento de 11,1 mes sin evidencia de complicaciones graves relacionadas con e
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39

Gundert, Timothy J., Alison L. Marsden, Weiguang Yang, and John F. LaDisa. "Optimization of Cardiovascular Stent Design Using Computational Fluid Dynamics." Journal of Biomechanical Engineering 134, no. 1 (2012). http://dx.doi.org/10.1115/1.4005542.

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Coronary stent design affects the spatial distribution of wall shear stress (WSS), which can influence the progression of endothelialization, neointimal hyperplasia, and restenosis. Previous computational fluid dynamics (CFD) studies have only examined a small number of possible geometries to identify stent designs that reduce alterations in near-wall hemodynamics. Based on a previously described framework for optimizing cardiovascular geometries, we developed a methodology that couples CFD and three-dimensional shape-optimization for use in stent design. The optimization procedure was fully-a
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40

Scicchitano, P., N. Locuratolo, A. Lillo, et al. "P209 THE FOLLOW–UP OF PATIENTS AFTER ACUTE CORONARY SYNDROME: THE APULIAN PONTE–ACS PROJECT." European Heart Journal Supplements 24, Supplement_C (2022). http://dx.doi.org/10.1093/eurheartj/suac012.201.

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Abstract Background Patients discharged after acute coronary syndrome (ACS) deserve a tight follow–up in order to optimize long–term pharmacological treatments and prevent the occurrence of adverse events. The aim of the PONTE–ACS Project was to evaluate the impact of a dedicated cooperative program between hospital and outpatient structures on the persistance on recommended therapies and long–term outcome occurrence in patients discharged after ACS. Materials and Methods This was a prospective, longitudina, cohort study. We enrolled patients who were discharged after ACS and/or after coronary
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Bai, Chaobo, Zhiying Chen, Xiaoqin Wu, et al. "Safety and efficacy comparison between OACs plus single antiplatelet and dual antiplatelet therapy in patients with cerebral venous sinus stenosis poststenting." BMC Neurology 22, no. 1 (2022). http://dx.doi.org/10.1186/s12883-022-02731-0.

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Abstract Background and purpose The present strategies regarding poststent management for cerebral venous sinus stenosis (CVSS) are inconsistent. Herein, we compared the safety and efficacy of oral anticoagulants (OACs) plus single antiplatelet therapy and dual antiplatelet therapy for CVSS poststenting. Methods A real-world observational study conducted from January 2009 through October 2019 enrolled patients who were diagnosed with CVSS and received stenting. Patients were divided into two groups according to the management they received poststenting. Group 1: OACs plus a single antiplatelet
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Padilla, Lucio, Jorge Tello y, and Pablo Lamelas. "Seguimiento extendido del bal�n liberador de paclitaxel Essential Pro para restenosis intrastent." REC: interventional cardiology, April 7, 2025. https://doi.org/10.24875/recic.m25000505.

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Boccuto, Fabiola, Laura Tammè, Claudio Iaconetti, et al. "738 Role of non-coding RNA uc.194 and uc.443+A in the intrastent restenosis." European Heart Journal Supplements 23, Supplement_G (2021). http://dx.doi.org/10.1093/eurheartj/suab138.

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Abstract Aims Vascular smooth muscle cells (VSMCs) play a key role in the vessel wall, being active partaker in vascular remodelling and influencing multiple pathophysiological phenomena, such as progression of atherosclerosis, in-stent restenosis and vascular reactivity. Recently antisense oligonucleotides have shown promising results as a therapeutic option. The aim of this study was to analyse the expression profile and function of T-UCRs in vascular smooth muscle cells (VSMCs)—both in vitro and in vivo—and to evaluate the effects of their inhibition by the use of specific antisense oligonu
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Oana, Stoia, Catrina Bianca, Puia Andreea, and Bitea Ioan Cornel. "Poster No. 030 Young patient with hyperhomocysteinemia and multiple atherosclerotic vascular lesions." Cardiovascular Research 118, Supplement_2 (2022). http://dx.doi.org/10.1093/cvr/cvac157.043.

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Abstract Background Hyperhomocysteinemia is usually defined as an elevation of plasma tHcy &amp;gt; 15 μmol/L with a prevalence ranging around 5–10% in the adult general population. In the last years, studies have demonstrated that moderate hyperhomocysteinemia is a frequent and independent risk factor for premature vascular disease in the coronary, cerebral, and peripheral arteries by impairing endothelium-dependent vasomotor responses in a way that increases risk for complications of atherosclerosis. Material and methods We present the case of a 45 years old man, without significant patholog
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Kimura, Shigeki, Yosuke Yamakami, Keisuke Kojima, et al. "Abstract 13746: Relationships between Neointimal Tissue Characteristics and Occurrence of Periprocedural Myocardial Infarction in Lesions with In-Stent Restenosis." Circulation 130, suppl_2 (2014). http://dx.doi.org/10.1161/circ.130.suppl_2.13746.

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Background: Recent studies have reported several types of neointimal tissues including neoatherosclerotic progression in stent restenosis. However, the influence of neointimal tissue characteristics on outcomes after percutaneous coronary intervention (PCI) for in-stent restenosis (ISR) remains unclear. Periprocedural myocardial infarction (PMI) is related to poor outcomes after PCI. We assessed relationships neointimal tissue characteristics and occurrence of PMI after PCI in ISR lesions. Methods: We investigated 45 ISR lesions in 45 stable angina pectoris (SAP) patients who underwent pre- an
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Gallicchio, Vito, Danilo Barbarisi, Pietro Armigliato, et al. "Outcomes Associated with the Use of the Auryon Peripheral Atherectomy System in a Hospital Setting: 1-Year Outcome." Cardiology and Cardiovascular Research 3, no. 1 (2025). https://doi.org/10.52106/2996-3885.1022.

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Background: Although endovascular approaches are the primary treatment for stenosis or occlusion of lower extremity arteries, major dissections and embolic events are the main risks. Therefore, there is a need to experiment with new technologies that not only limit these risks but also achieve the targeted clinical outcomes. Methods: The Auryon (AngioDynamics) atherectomy system uses a 355nm wavelength laser platform that enables the use of longer wavelengths and shorter pulses to produce a groundbreaking delivery of short UV laser pulse combined with dedicated optical catheters. This study ev
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Bettella, N., M. Previtero, A. Ruocco, D. Muraru, S. Iliceto, and L. P. Badano. "P167 The burden of post-actinic heart disease: a case of severe valvular and coronary artery disease in a cancer survivor." European Heart Journal - Cardiovascular Imaging 21, Supplement_1 (2020). http://dx.doi.org/10.1093/ehjci/jez319.041.

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Abstract Background A 47-year old female complaining of exertional dyspnoea (NYHA class III) was admitted at our Cardiology department. She had a history of nodular sclerosis Hodgkin lymphoma (HL), treated with chemo- and radiotherapy, and complicated by post-actinic pneumopathy and cardiopathy. At the age of 39, she had undergone coronary artery bypass grafting with left internal mammal artery (LIMA) to left anterior descendent artery and saphenous vein to obtuse marginal branch, and aortic valve replacement with a mechanical prosthesis due to severe aortic stenosis. Some years later, she had
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Cacciapuoti, Fulvio, Ciro Mauro, Davide D’Andrea, Valentina Capone, Carlo Liguori, and Federico Cacciapuoti. "Epicardial adipose tissue and residual cardiovascular risk: a comprehensive case analysis and therapeutic insights with Liraglutide." Journal of Cardiovascular Medicine, June 21, 2024. http://dx.doi.org/10.2459/jcm.0000000000001652.

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Introduction The role of epicardial adipose tissue (EAT) in cardiovascular health has undergone a paradigm shift in recent years, evolving from a passive reservoir into a dynamic contributor to cardiovascular risk. This case critically examines the multifaceted functions of EAT, explores its implications for cardiovascular risk, and discusses the potential benefits of the GLP-1 receptor agonist Liraglutide in mitigating its effects. Case presentation We present the case of a 62-year-old male patient who is obese, hypertensive, and has a history of chronic coronary syndrome. He was admitted to
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Micillo, M., M. Cocco, A. Cossu, et al. "P417 ASSESSMENT OF RESIDUAL CARDIOVASCULAR RISK AFTER STENTING: THE ROLE OF IMAGING." European Heart Journal Supplements 24, Supplement_C (2022). http://dx.doi.org/10.1093/eurheartj/suac012.402.

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Abstract Background Reduction of residual risk after myocardial infarction (MI) represents the main goal in secondary prevention. Imaging may provide additional evidence beyond the monitoring of risk factors. Clinical Case In June 2019 a 29–year old man, Pakistani ethnicity, former smoker with family history of cardiovascular disease experienced a myocardial infarction without ST–segment elevation. Coronary angiography revealed a severe disease of circumflex branch (LCx) and of second obtuse marginal branch (OM2) treated with drug eluting stent (DES) implantation. A strong medical therapy was
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Rochira, Carla. "673 A CRACK AND A CLOT." European Heart Journal Supplements 24, Supplement_K (2022). http://dx.doi.org/10.1093/eurheartjsupp/suac121.539.

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Abstract A 74-year-old man with a history of ischaemic heart disease (multiple percutaneous coronary interventions (PCI)), broke his ankle. Therefore, he discontinued dual antiplatelet therapy (DAPT) -acetylsalicylic acid plus clopidogrel- and started enoxaparin sodium 4000 UI/day on medical advice. A few days later, he was admitted to the emergency department for refractory chest pain, vomit and syncope. Twelve-lead electrocardiogram (ECG) showed a sinus rhythm interrupted by frequent premature ventricular contractions in a pattern of trigeminy. The transthoracic echocardiogram revealed a mil
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